Skip to Main Content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

School of Pharmacy : Arien-Zakay Hadar

Researchers

 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Chiu W-, Kovacheva L, Musgrove RE, Arien-Zakay H, Koprich JB, Brotchie JM, et al. α-Synuclein–induced Kv4 channelopathy in mouse vagal motoneurons drives nonmotor parkinsonian symptoms. Sci Adv 2021;7(11).

(2) Lahiani A, Zahavi E, Netzer N, Ofir R, Pinzur L, Raveh S, et al. Human PLacental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF. Biochim Biophys Acta Mol Cell Res 2015;1853(2):422-430.

(3) Arien-Zakay H, Gincberg G, Nagler A, Cohen G, Liraz-Zaltsman S, Trembovler V, et al. Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury. J Neurotrauma 2014;31(16):1405-1416.

(4) Bercu MM, Arien-Zakay H, Stoler D, Lecht S, Lelkes PI, Samuel S, et al. Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs. J Mol Neurosci 2013;51(2):249-261.

(5) Gincberg G, Arien-Zakay H, Lazarovici P, Lelkes PI. Neural stem cells: Therapeutic potential for neurodegenerative diseases. Br Med Bull 2012;104(1):7-19.

(6) Ettinger K, Lecht S, Arien-Zakay H, Cohen G, Aga-Mizrachi S, Yanay N, et al. Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model. Cell Signal 2012;24(12):2378-2388.

(7) Cohen G, Lecht S, Arien-Zakay H, Ettinger K, Amsalem O, Oron-Herman M, et al. Bio-Imaging of Colorectal Cancer Models Using Near Infrared Labeled Epidermal Growth Factor. PLoS ONE 2012;7(11).

(8) Lazarovici P, Cohen G, Arien-Zakay H, Chen J, Zhang C, Chopp M, et al. Multimodal neuroprotection induced by PACAP38 in Oxygen-glucose deprivation and middle cerebral artery occlusion stroke models. J Mol Neurosci 2012;48(3):526-540.

(9) Lecht S, Rotfeld E, Arien-Zakay H, Tabakman R, Matzner H, Yaka R, et al. Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal. Int J Dev Neurosci 2012;30(6):465-469.

(10) Momic T, Arlinghaus FT, Arien-Zakay H, Katzhendler J, Eble JA, Marcinkiewicz C, et al. Pharmacological aspects of Vipera xantina palestinae venom. Toxins 2011;3(11):1420-1432.

(11) Arien-Zakay H, Lecht S, Nagler A, Lazarovici P. Neuroprotection by human umbilical cord blood-derived progenitors in ischemic brain injuries. Arch Ital Biol 2011;149(2):233-245.

(12) Arien-Zakay H, Lecht S, Nagler A, Lazarovici P. Human umbilical cord blood stem cells: Rational for use as a neuroprotectant in ischemic brain disease. Int J Mol Sci 2010;11(9):3513-3528.

(13) Lecht S, Arien-Zakay H, Wagenstein Y, Inoue S, Marcinkiewicz C, Lelkes PI, et al. Transient signaling of Erk1/2, Akt and PLCγ induced by nerve growth factor in brain capillary endothelial cells. Vasc Pharmacol 2010;53(3-4):107-114.

(14) Arien-Zakay H, Lazarovici P, Nagler A. Tissue regeneration potential in human umbilical cord blood. Best Pract Res Clin Haematol 2010;23(2):291-303.

(15) Lecht S, Arien-Zakay H, Kohan M, Lelkes PI, Lazarovici P. Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells. Mol Cell Biochem 2010;339(1-2):201-213.

(16) Lecht S, Arien-Zakay H, Marcinkiewicz C, Lelkes PI, Lazarovici P. Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of erk phosphorylation. J Mol Neurosci 2010;41(1):183-192.

(17) Lecht S, Foerster C, Arien-Zakay H, Marcinkiewicz C, Lazarovici P, Lelkes PI. Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2. In Vitro Cell Dev Biol Anim 2010;46(5):469-476.

(18) Arien-Zakay H, Lecht S, Perets A, Roszell B, Lelkes PI, Lazarovici P. Quantitative assessment of neuronal differentiation in three-dimensional collagen gels using enhanced green fluorescence protein expressing PC12 pheochromocytoma cells. J Mol Neurosci 2009;37(3):225-237.

(19) Arien-Zakay H, Lecht S, Bercu MM, Tabakman R, Kohen R, Galski H, et al. Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors. Exp Neurol 2009;216(1):83-94.

(20) Arien-Zakay H, Lecht S, Bercu MM, Amariglio N, Rechavi G, Galski H, et al. Interferon-γ-induced neuronal differentiation of human umbilical cord blood-derived progenitors. Leukemia 2009;23(10):1790-1800.

(21) Arien-Zakay H, Nagler A, Galski H, Lazarovici P. Neuronal conditioning medium and nerve growth factor induce neuronal differentiation of collagen-adherent progenitors derived from human umbilical cord blood. J Mol Neurosci 2007;32(3):179-191.

(22) Tabakman R, Jiang H, Shahar I, Arien-Zakay H, Levine RA, Lazarovici P. Neuroprotection by NGF in the PC12 in vitro OGD model: Involvement of mitogen-activated protein kinases and gene expression. Ann New York Acad Sci 2005;1053:84-96.

(23) Tabakman R, Lecht S, Sephanova S, Arien-Zakay H, Lazarovici P. Interactions between the cells of the immune and nervous system: Neurotrophins as neuroprotection mediators in CNS injury. Prog Brain Res 2004;146:385-401.

(24) Arien H, Wiser O, Arkin IT, Leonov H, Atlas D. Syntaxin 1A modulates the voltage-gated L-type calcium channel (Cavl.2) in a cooperative manner. J Biol Chem 2003;278(31):29231-29239.