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School of Pharmacy : Tsvelikhovsky Dmitry


 Last updated December 2021 - School of Pharmacy

List of Publications

(1) Lahiani A, Haham-Geula D, Lankri D, Cornell-Kennon S, Schaefer EM, Tsvelikhovsky D, et al. Neurotropic activity and safety of methylene-cycloalkylacetate (MCA) derivative 3-(3-allyl-2-methylenecyclohexyl) propanoic acid. ACS Chem Neurosci 2020;11(17):2577-2589.

(2) Mostinski Y, Lankri D, Konovalov Y, Nataf R, Tsvelikhovsky D. Proline-promoted dehydroxylation of α-ketols. Chem Sci 2019;10(40):9345-9350.

(3) Lankri D, Haham D, Lahiani A, Lazarovici P, Tsvelikhovsky D. Methylene-Cycloalkylacetate (MCA) Scaffold-Based Compounds as Novel Neurotropic Agents. ACS Chem Neurosci 2018;9(4):691-698.

(4) Lankri D, Mostinski Y, Tsvelikhovsky D. Palladium-Catalyzed Cascade Assembly of Tricyclic Spiroethers from Diene-Alcohol Precursors. J Org Chem 2017;82(18):9452-9463.

(5) Mostinski Y, Noy G, Kumar R, Tsvelikhovsky D, Priel A. Tricyclic Spirolactones as Modular TRPV1 Synthetic Agonists. ACS Chem Neurosci 2017;8(8):1688-1696.

(6) Lankri D, Albarghouti G, Mahameed M, Tsvelikhovsky D. Multifaceted α-Enaminone: Adaptable Building Block for Synthesis of Heterocyclic Scaffolds Through Conceptually Distinct 1,2-, 1,3-, 1,4-, and C-O Bond Forming Annulations. J Org Chem 2017;82(14):7101-7113.

(7) Mostinski Y, Lankri D, Tsvelikhovsky D. Transition-Metal-Catalyzed Synthesis of Spirolactones. Synthesis 2017;49(11):2361-2373.

(8) Mostinski Y, Kotikalapudi R, Valerio V, Nataf R, Tsvelikhovsky D. Palladium-Catalyzed Cyclization of Free Hydroxyalkenoic Acids: Regio- and Chemoselective Access to Methylene Lactones. Adv Synth Catal 2017;359(7):1164-1169.

(9) Valerio V, Mostinski Y, Kotikalapudi R, Tsvelikhovsky D. Stereo- and Regioselective Synthesis of Tricyclic Spirolactones by Diastereoisomeric Differentiation of a Collective Key Precursor. Chem Eur J 2016;22(8):2640-2647.

(10) Albarghouti G, Kotikalapudi R, Lankri D, Valerio V, Tsvelikhovsky D. Cascade Pd(ii)-catalyzed Wacker lactonization-Heck reaction: Rapid assembly of spiranoid lactones. Chem Commun 2016;52(15):3095-3098.

(11) Mostinski Y, Valerio V, Lankri D, Tsvelikhovsky D. Synthesis of Tricyclic Spiranoid Lactones via I2/Sm(II)- and I2/Pd(0)-Mediated Cyclizations of a Common Cycloalkylmethylene Precursor. J Org Chem 2015;80(21):10464-10473.

(12) Tsvelikhovsky D, Buchwald SL. Erratum: Synthesis of heterocycles via Pd-ligand controlled cyclization of 2-chloro-N -(2-vinyl)aniline: Preparation of carbazoles, indoles, dibenzazepines, and acridines (Journal of the American Chemical Society (2010) 132 (14048-14051) DOI: 10.1021/ja107511g). J Am Chem Soc 2012;134(40):16917.

(13) Tsvelikhovsky D, Buchwald SL. Concise palladium-catalyzed synthesis of dibenzodiazepines and structural analogues. J Am Chem Soc 2011;133(36):14228-14231.

(14) Tsvelikhovsky D, Buchwald SL. Synthesis of heterocycles via Pd-ligand controlled cyclization of 2-chloro-N-(2-vinyl)aniline: Preparation of carbazoles, indoles, dibenzazepines, and acridines. J Am Chem Soc 2010;132(40):14048-14051.

(15) Baruch AR-, Tsvelikhovsky D, Schwarze M, Schomäcker R, Fanun M, Blum J. Dependence of the Heck coupling in aqueous microemulsion by supported palladium acetate on the surfactant and on the hydrophobicity of the support. J Mol Catal A Chem 2010;323(1-2):65-69.

(16) Tsvelikhovsky D, Popov I, Gutkin V, Rozin A, Shvartsman A, Blum J. On the involvement of palladium nanoparticles in the Heck and Suzuki reactions. Eur J Org Chem 2009(1):98-102.

(17) Tsvelikhovsky D, Pessing D, Avnir D, Blum J. Forcing a cis-product by matrix imprinting: Heck reaction catalyzed by palladium acetate entrapped within cis-imprinted sol-gel derived silicates. Adv Synth Catal 2008;350(18):2856-2858.

(18) Tsvelikhovsky D, Blum J. Three phase microemulsion/sol-gel system for aqueous C-C coupling of hydrophobic substrates. Eur J Org Chem 2008(14):2417-2422.

(19) Tsvelikhovsky D, Schumann H, Blum J. Cerium(IV)-promoted ethylation of Schiff bases by triethylaluminum. Synthesis 2006(11):1819-1822.

(20) Tsvelikhovsky D, Gelman D, Molander GA, Blum J. Lanthanide-promoted ethylation of schiff bases by triethylaluminum. Org Lett 2004;6(12):1995-1997.

(21) Gelman D, Tsvelikhovsky D, Molander GA, Blum J. Palladium-catalyzed cross-alkynylation of aryl bromides by sodium tetraalkynylaluminates. J Org Chem 2002;67(18):6287-6290.