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The Faculty of Medicine - Microbiology and Molecular Genetics: Ben-Yehuda Sigal


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Baidya AK, Rosenshine I, Ben-Yehuda S. Donor-delivered cell wall hydrolases facilitate nanotube penetration into recipient bacteria. Nat Commun 2020;11(1).

(2) Hashuel R, Ben-Yehuda S. Aging of a bacterial colony enforces the evolvement of nondifferentiating mutants. mBio 2019;10(5).

(3) Torres R, Carrasco B, Gándara C, Baidya AK, Ben-Yehuda S, Alonso JC. Bacillus subtilis DisA regulates RecA-mediated DNA strand exchange. Nucleic Acids Res 2019;47(10):5141-5154.

(4) Habusha M, Tzipilevich E, Fiyaksel O, Ben-Yehuda S. A mutant bacteriophage evolved to infect resistant bacteria gained a broader host range. Mol Microbiol 2019;111(6):1463-1475.

(5) Pal RR, Baidya AK, Mamou G, Bhattacharya S, Socol Y, Kobi S, et al. Pathogenic E. coli Extracts Nutrients from Infected Host Cells Utilizing Injectisome Components. Cell 2019;177(3):683-696.e18.

(6) Bhattacharya S, Baidya AK, Pal RR, Mamou G, Gatt YE, Margalit H, et al. A Ubiquitous Platform for Bacterial Nanotube Biogenesis. Cell Rep 2019;27(2):334-342.e10.

(7) Zhou B, Semanjski M, Orlovetskie N, Bhattacharya S, Alon S, Argaman L, et al. Arginine dephosphorylation propels spore germination in bacteria. Proc Natl Acad Sci U S A 2019;116(28):14228-14237.

(8) Baidya AK, Bhattacharya S, Dubey GP, Mamou G, Ben-Yehuda S. Bacterial nanotubes: a conduit for intercellular molecular trade. Curr Opin Microbiol 2018;42:1-6.

(9) Stempler O, Baidya AK, Bhattacharya S, Malli Mohan GB, Tzipilevich E, Sinai L, et al. Interspecies nutrient extraction and toxin delivery between bacteria. Nat Commun 2017;8(1).

(10) Singer E, Silas YBH, Ben-Yehuda S, Pines O. Bacterial fumarase and L-malic acid are evolutionary ancient components of the DNA damage response. eLife 2017;6.

(11) Mamou G, Fiyaksel O, Sinai L, Ben-Yehuda S. Deficiency in lipoteichoic acid synthesis causes a failure in executing the colony developmental program in Bacillus subtilis. Front Microbiol 2017;8(OCT).

(12) Tzipilevich E, Habusha M, Ben-Yehuda S. Acquisition of Phage Sensitivity by Bacteria through Exchange of Phage Receptors. Cell 2017;168(1-2):186-199.e12.

(13) Mamou G, Malli Mohan GB, Rouvinski A, Rosenberg A, Ben-Yehuda S. Early Developmental Program Shapes Colony Morphology in Bacteria. Cell Rep 2016;14(8):1850-1857.

(14) Dubey GP, Malli Mohan GB, Dubrovsky A, Amen T, Tsipshtein S, Rouvinski A, et al. Architecture and Characteristics of Bacterial Nanotubes. Dev Cell 2016;36(4):453-461.

(15) Sinai L, Ben-Yehuda S. Commentary: Changes in Bacillus spore small molecules, rRNA, germination, and outgrowth after extended sublethal exposure to various temperatures: Evidence that protein synthesis is not essential for spore germination. Front Microbiol 2016;7(DEC).

(16) Rosenberg A, Soufi B, Ravikumar V, Soares NC, Krug K, Smith Y, et al. Phosphoproteome dynamics mediate revival of bacterial spores. BMC Biol 2015;13(1).

(17) Elbaz M, Ben-Yehuda S. Following the fate of bacterial cells experiencing sudden chromosome loss. mBio 2015;6(3):1-11.

(18) Sinai L, Rosenberg A, Smith Y, Segev E, Ben-Yehuda S. The molecular timeline of a reviving bacterial spore. Mol Cell 2015;57(4):695-707.

(19) Balasubramaniam S, Ben-Yehuda S, Pautot S, Jesorka A, Lio' P, Koucheryavy Y. A review of experimental opportunities for molecular communication. Nano Commun Netw 2013;4(2):43-52.

(20) Segev E, Rosenberg A, Mamou G, Sinai L, Ben-Yehuda S. Molecular kinetics of reviving bacterial spores. J Bacteriol 2013;195(9):1875-1882.

(21) Garti-levi S, Eswara A, Smith Y, Fujita M, Ben-Yehuda S. Novel modulators controlling entry into sporulation in Bacillus subtilis. J Bacteriol 2013;195(7):1475-1483.

(22) Wexselblatt E, Oppenheimer-Shaanan Y, Kaspy I, London N, Schueler-Furman O, Yavin E, et al. Relacin, a Novel Antibacterial Agent Targeting the Stringent Response. PLoS Pathog 2012;8(9).

(23) Rosenberg A, Sinai L, Smith Y, Ben-Yehuda S. Dynamic expression of the translational machinery during Bacillus subtilis life cycle at a single cell level. PLoS ONE 2012;7(7).

(24) Segev E, Smith Y, Ben-Yehuda S. RNA dynamics in aging bacterial spores. Cell 2012;148(1-2):139-149.

(25) Oppenheimer-Shaanan Y, Wexselblatt E, Katzhendler J, Yavin E, Ben-Yehuda S. C-di-AMP reports DNA integrity during sporulation in Bacillus subtilis. EMBO Rep 2011;12(6):594-601.

(26) Nevo-Dinur K, Nussbaum-Shochat A, Ben-Yehuda S, Amster-Choder O. Translation-independent localization of mRNA in E. coli. Science 2011;331(6020):1081-1084.

(27) Dubey GP, Ben-Yehuda S. Intercellular nanotubes mediate bacterial communication. Cell 2011;144(4):590-600.

(28) Elbaz M, Ben-Yehuda S. The metabolic enzyme mana reveals a link between cell wall integrity and chromosome morphology. PLoS Genet 2010;6(9).

(29) Meyerovich M, Mamou G, Ben-Yehuda S. Visualizing high error levels during gene expression in living bacterial cells. Proc Natl Acad Sci U S A 2010;107(25):11543-11548.

(30) Berlatzky IA, Rouvinski A, Ben-Yehuda S. Spatial organization of a replicating bacterial chromosome. Proc Natl Acad Sci U S A 2008;105(37):14136-14140.

(31) Garti-Levi S, Hazan R, Kain J, Fujita M, Ben-Yehuda S. The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis. Mol Microbiol 2008;69(4):1018-1028.

(32) Marquis KA, Burton BM, Nollmann M, Ptacin JL, Bustamante C, Ben-Yehuda S, et al. SpoIIIE strips proteins off the DNA during chromosome translocation. Genes Dev 2008;22(13):1786-1795.

(33) Hazan R, Ben-Yehuda S. Erratum: Resolving chromosome segregation in bacteria (Journal of Molecular Microbiology and Biotechnology (2006) 11, (126-139)). J Mol Microbiol Biotechnol 2007;12(3-4):273.

(34) Bejerano-Sagie M, Oppenheimer-Shaanan Y, Berlatzky I, Rouvinski A, Meyerovich M, Ben-Yehuda S. A Checkpoint Protein That Scans the Chromosome for Damage at the Start of Sporulation in Bacillus subtilis. Cell 2006;125(4):679-690.

(35) Carniol K, Ben-Yehuda S, King N, Losick R. Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis. J Bacteriol 2005;187(10):3511-3520.

(36) Ben-Yehuda S, Fujita M, Liu XS, Gorbatyuk B, Skoko D, Yan J, et al. Defining a centromere-like element in Bacillus subtilis by identifying the binding sites for the chromosome-anchoring protein RacA. Mol Cell 2005;17(6):773-782.

(37) Ben-Yehuda S, Rudner DZ, Losick R. Assembly of the SpoIIIE DNA Translocase Depends on Chromosome Trapping in Bacillus subtilis. Curr Biol 2003;13(24):2196-2200.

(38) Eichenberger P, Jensen ST, Conlon EM, Van Ooij C, Silvaggi J, González-Pastor J-, et al. The σE regulon and the identification of additional sporulation genes in Bacillus subtilis. J Mol Biol 2003;327(5):945-972.

(39) Ben-Yehuda S, Rudner DZ, Losick R. RacA, a bacterial protein that anchors chromosomes to the cell poles. Science 2003;299(5606):532-536.

(40) Ben-Yehuda S, Losick R. Asymmetric cell division in B. subtilis involves a spiral-like intermediate of the cytokinetic protein FtsZ. Cell 2002;109(2):257-266.

(41) Branda SS, González-Pastor JE, Ben-Yehuda S, Losick R, Kolter R. Fruiting body formation by Bacillus subtilis. Proc Natl Acad Sci U S A 2001;98(20):11621-11626.

(42) Ben-Yehuda S, Dix I, Russell CS, McGarvey M, Beggs JD, Kupiec M. Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 2000;156(4):1503-1517.

(43) Russell CS, Ben-Yehuda S, Dix I, Kupiec M, Beggs JD. Functional analyses of interacting factors involved in both pre-mRNA splicing and cell progression in Saccharomyces cerevisiae. RNA 2000;6(11):1565-1572.

(44) Ben-Yehuda S, Russell CS, Dix I, Beggs JD, Kupiec M. Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression. Genetics 2000;154(1):61-71.

(45) Boger-Nadjar E, Vaisman N, Ben-Yehuda S, Kassir Y, Kupiec M. Efficient initiation of S-phase in yeast requires Cdc40p, a protein involved in pre-mRNA splicing. Mol Gen Genet 1998;260(2-3):232-241.

(46) Vaisman N, Tsouladze A, Robzyk K, Ben-Yehuda S, Kupiec M, Kassir Y. The role of Saccharomyces cerevisiae Cdc40p in DNA replication and mitotic spindle formation and/or maintenance. Molec Gen Genet 1995;247(2):123-136.