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The Faculty of Medicine - Microbiology and Molecular Genetics: Rokem Stefan

Researchers

 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Rokem JS. TCA Cycle Organic Acids Produced by Filamentous Fungi: The Building Blocks of the Future. Gd Chall Biol Biotechnol 2020:439-476.

(2) Backer R, Rokem JS, Ilangumaran G, Lamont J, Praslickova D, Ricci E, et al. Plant growth-promoting rhizobacteria: Context, mechanisms of action, and roadmap to commercialization of biostimulants for sustainable agriculture. Front Plant Sci 2018;871.

(3) Letnik I, Avrahami R, Port R, Greiner A, Zussman E, Rokem JS, et al. Biosorption of copper from aqueous environments by Micrococcus luteus in cell suspension and when encapsulated. Int Biodeterior Biodegrad 2017;116:64-72.

(4) Letnik I, Avrahami R, Rokem JS, Greiner A, Zussman E, Greenblatt C. Living Composites of Electrospun Yeast Cells for Bioremediation and Ethanol Production. Biomacromolecules 2015;16(10):3322-3328.

(5) Goldberg I, Rokem JS. Fumaric Acid Biosynthesis and Accumulation. Bioprocessing of Renewable Resources to Commodity Bioproducts; 2014. p. 409-434.

(6) Rokem JS, Vongsangnak W, Nielsen J. Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria. Biotechnol Bioeng 2011;108(11):2770-2775.

(7) Young M, Artsatbanov V, Beller HR, Chandra G, Chater KF, Dover LG, et al. Genome sequence of the fleming strain of Micrococcus luteus, a simple free-living actinobacterium. J Bacteriol 2010;192(3):841-860.

(8) Goldberg I, Rokem JS. Organic and Fatty Acid Production, Microbial. Encyclopedia of Microbiology; 2009. p. 421-442.

(9) Rokem JS, Lantz AE, Nielsen J. Systems biology of antibiotic production by microorganisms. Nat Prod Rep 2007;24(6):1262-1287.

(10) Goldberg I, Rokem JS, Pines O. Organic acids: Old metabolites, new themes. J Chem Technol Biotechnol 2006;81(10):1601-1611.

(11) Rubinstein A, Radai R, Friedman M, Fischer P, Rokem JS. The effect of intestinal bacteria adherence on drug diffusion through solid films under stationary conditions. Pharm Res 1997;14(4):503-507.

(12) Friedberg D, Peleg Y, Monsonego A, Maissi S, Battat E, Rokem JS, et al. The fumR gene encoding fumarase in the filamentous fungus Rhizopus oryzae: cloning, structure and expression. Gene 1995;163(1):139-144.

(13) Spivak IR, Rokem JS. Analyses of possible steady states for mixed culture grown on natural gas. Ecol Model 1995;80(2-3):257-278.

(14) Spivak IR, Rokem JS. Mathematical simulations of man-made microbial mixture grown on natural gas. Ecol Model 1994;74(3-4):287-304.

(15) Rubinstein A, Radai R, Ezra M, Pathak S, Rokem JS. In Vitro Evaluation of Calcium Pectinate: A Potential Colon-Specific Drug Delivery Carrier. Pharm Res 1993;10(2):258-263.

(16) Rubinstein A, Ezra M, Rokem JS. Adhesion of bacteria on pectin casted films. Microbios 1992;70(284-285):163-170.

(17) Rokem JS, Goldberg I. Oxidation pathways in methylotrophs. Biotechnology 1991;18:111-126.

(18) Neufeld RJ, Peleg Y, Rokem JS, Pines O, Goldberg I. l-Malic acid formation by immobilized Saccharomyces cerevisiae amplified for fumarase. Enzyme Microb Technol 1991;13(12):991-996.

(19) Battat E, Peleg Y, Bercovitz A, Rokem JS, Goldberg I. Optimization of L‐malic acid production by Aspergillus flavus in a stirred fermentor. Biotechnol Bioeng 1991;37(11):1108-1116.

(20) Rokem JS, Schön A, Söll D. Sequence of a tRNAGly from Streptomyces coelicolor. Nucleic Acids Res 1990;18(13):3988.

(21) Bar R, Rokem JS. Cyclodextrin-stimulated fermentation of prodigiosin by Serratiamarcescens. Biotechnol Lett 1990;12(6):447-448.

(22) Peleg Y, Rokem JS, Goldberg I. A simple plate-assay for the screening of l-malic acid producing microorganisms. FEMS Microbiol Lett 1990;67(3):233-236.

(23) Peleg Y, Rokem JS, Goldberg I, Pines O. Inducible overexpression of the FUM1 gene in Saccharomyces cerevisiae: Localization of fumarase and efficient fumaric acid bioconversion to L-malic acid. Appl Environ Microbiol 1990;56(9):2777-2783.

(24) Bercovitz A, Peleg Y, Battat E, Rokem JS, Goldberg I. Localization of pyruvate carboxylase in organic acid-producing Aspergillus strains. Appl Environ Microbiol 1990;56(6):1594-1597.

(25) Battat E, Rokem JS, Goldberg I. Growth of Dioscorea deltoidea at high sugar concentrations. Plant Cell Rep 1989;7(8):652-654.

(26) Geron M, Botershvili I, Rokem JS. Scanning electron microscopy of Serratia marcescens producing prodigiosin. Microbios 1988;54(1):41-44.

(27) Peleg Y, Koder S, Rokem JS, Chet I, Goldberg I. Phaseollin production in cell suspensions and whole plants of Phaseolus vulgaris. Plant Cell Tiss Organ Cult 1987;9(3):207-215.

(28) Rokem JS, Zomer E. Scale up of the production of xylitol dehydrogenase and alcohol dehydrogenase from Pachysolen tannophilus grown on xylose. Appl Microbiol Biotechnol 1987;26(3):231-233.

(29) Rokem JS, Weitzman P. Prodigiosin formation by Serratia marcescens in a chemostat. Enzyme Microb Technol 1987;9(3):153-155.

(30) Zomer E, Er-El Z, Rokem JS. Production of intracellular enzymes by enzymatic treatment of yeast. Enzyme Microb Technol 1987;9(5):281-284.

(31) Rokem JS, Klein D, Toder H, Zomer E. Degradation of fungal cell walls taking into consideration the polysaccharide composition. Enzyme Microb Technol 1986;8(10):588-592.

(32) Rokem JS, Goldberg I. SECONDARY METABOLITES FROM PLANT CELLS SUSPENSION CULTURES: METHODS FOR YIELD IMPROVEMENT. Advances in Biotechnological Processes; 1985. p. 241-274.

(33) Rokem JS, Tal B, Goldberg I. Methods for increasing diosgenin production by dioscorea cells in suspension cultures. J Nat Prod 1985;48(2):210-222.

(34) Rokem JS. Israel squeezed out [2]. Nature 1984;307(5950):408.

(35) Rokem JS, Schwarzberg J, Goldberg I. Autoclaved fungal mycelia increase diosgenin production in cell suspension cultures of Dioscorea deltoidea. Plant Cell Rep 1984;3(4):159-160.

(36) Tal B, Rokem JS, Gressel J, Goldberg I. The effect of chlorophyll-bleaching herbicides on growth, carotenoid and diosgenin levels in cell suspension cultures of Dioscorea deltoidea. Phytochemistry 1984;23(6):1333-1335.

(37) Tal B, Rokem JS, Goldberg I. Timing of diosgenin appearance in suspension cultures of Dioscorea deltoidea. Planta Med 1984;50(3):239-241.

(38) Tal B, Tamir I, Rokem JS, Goldberg I. Isolation and characterization of an intermediate steroid metabolite in diosgenin biosynthesis in suspension cultures of Dioscorea deltoidea cells. Biochem J 1984;219(2):619-624.

(39) Tal B, Rokem JS, Goldberg I. Factors affecting growth and product formation in plant cells grown in continuous culture. Plant Cell Rep 1983;2(4):219-222.

(40) Hurley H, Rokem JS. Some insights into the possible development of a biosynthetic pathway and biological function for anthramycin in Streptomyces refuineus. Folia Microbiol 1983;28(3):229-236.

(41) Hurley LH, Rokem JS. Biosynthesis of the antitumor antibiotic CC-1065 by streptomyces zelensis. J Antibiot 1983;36(4):383-390.

(42) Swenson DH, Li LH, Petzold GL, Dayton BD, Wallace TL, Lin AH, et al. Mechanism of Interaction of CC-1065 (NSC 298223) with DNA. Cancer Res 1982;42(7):2821-2828.

(43) Rokem JS, Hurley LH. Sensitivity and permeability of the anthramycin producing organism streptomyces refuineus to anthramycin and structurally related antibiotics. J Antibiot 1981;34(9):1171-1174.

(44) Hurley LH, Rokem JS, Petrusek RL. Proposed structures of the pyrrolo(1,4)benzodiazepine antibiotic-deoxyribonucleic acid adducts. Biochem Pharmacol 1980;29(9):1307-1310.

(45) Rokem JS, Goldberg I, Mateles RI. Growth of mixed cultures of bacteria on methanol. J Gen Microbiol 1980;116(1):225-232.

(46) Rokem JS, Reichler J, Goldberg I. Electron microscopy of methanol-utilizing bacteria. Antonie Van Leeuwenhoek 1978;44(2):123-127.

(47) Rokem (Rock) JS, Goldberg I, Mateles RI. Maintenance requirements for bacteria growing on C1‐compounds. Biotechnol Bioeng 1978;20(10):1557-1564.