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The Faculty of Medicine - Medical Neurobiology: Yanai Joseph

Researchers

Last updated December 2021 - Medical Neurobiology

List of Publications

(1) Rimawi I, Ornoy A, Yanai J. Paternal and/or maternal preconception-induced neurobehavioral teratogenicity in animal and human models. Brain Res Bull 2021;174:103-121.

(2) Kozhuhov A, Tfilin M, Turgeman G, Ornoy A, Yanai J, Abookasis D. Implementation of a six-around-one optical probe based on diffuse light spectroscopy for study of cerebral properties in a murine mouse model of autism spectrum disorder. Appl Opt 2020;59(23):6809-6816.

(3) Weinstein-Fudim L, Ergaz Z, Turgeman G, Yanai J, Szyf M, Ornoy A. Gender related changes in gene expression induced by valproic acid in a mouse model of autism and the correction by s-adenosyl methionine. Does it explain the gender differences in autistic like behavior? Int J Mol Sci 2019;20(21).

(4) Yanai J, Vigoda MJ, Ornoy A. Reversal of neurobehavioral teratogenicity in animal models and human: Three decades of progress. Brain Res Bull 2019;150:328-342.

(5) Ornoy A, Weinstein-Fudim L, Tfilin M, Ergaz Z, Yanai J, Szyf M, et al. S-adenosyl methionine prevents ASD like behaviors triggered by early postnatal valproic acid exposure in very young mice. Neurotoxicol Teratol 2019;71:64-74.

(6) Ornoy A, Koren G, Yanai J. Is post exposure prevention of teratogenic damage possible: Studies on diabetes, valproic acid, alcohol and anti folates in pregnancy: Animal studies with reflection to human. Reprod Toxicol 2018;80:92-104.

(7) Pinkas A, Turgeman G, Tayeb S, Yanai J. An avian model for ascertaining the mechanisms of organophosphate neuroteratogenicity and its therapy with mesenchymal stem cell transplantation. Neurotoxicol Teratol 2015;50:73-81.

(8) Hamisha KN, Tfilin M, Yanai J, Turgeman G. Mesenchymal Stem Cells Can Prevent Alterations in Behavior and Neurogenesis Induced by Aß25–35 Administration. J Mol Neurosci 2015;55(4):1006-1013.

(9) Abdul-Ghani S, Yanai J, Abdul-Ghani R, Pinkas A, Abdeen Z. The teratogenicity and behavioral teratogenicity of di(2-ethylhexyl) phthalate (DEHP) and di-butyl Phthalate (DBP) in a chick model. Neurotoxicol Teratol 2012;34(1):56-62.

(10) Turgeman G, Pinkas A, Slotkin TA, Tfilin M, Langford R, Yanai J. Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells. J Neurosci Res 2011;89(8):1185-1193.

(11) Dotan S, Pinkas A, Slotkin TA, Yanai J. An avian model for the reversal of neurobehavioral teratogenicity with neural stem cells. Neurotoxicol Teratol 2010;32(4):481-488.

(12) Pinkas A, Slotkin TA, Brick-Turin Y, Van der Zee EA, Yanai J. Neurobehavioral teratogenicity of perfluorinated alkyls in an avian model. Neurotoxicol Teratol 2010;32(2):182-186.

(13) Kazma M, Izrael M, Revel M, Chebath J, Yanai J. Survival, differentiation, and reversal of heroin neurobehavioral teratogenicity in mice by transplanted neural stem cells derived from embryonic stem cells. J Neurosci Res 2010;88(2):315-323.

(14) Yanai J, Brick-Turin Y, Dotan S, Langford R, Pinkas A, Slotkin TA. A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity. Neurotoxicol Teratol 2010;32(1):109-113.

(15) Billauer-Haimovitch H, Slotkin TA, Dotan S, Langford R, Pinkas A, Yanai J. Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation. Behav Brain Res 2009;205(2):499-504.

(16) Yanai J, Pinkas A, Seidler FJ, Ryde IT, Van der Zee EA, Slotkin TA. Neurobehavioral teratogenicity of sarin in an avian model. Neurotoxicol Teratol 2009;31(6):406-412.

(17) Slotkin TA, Seidler FJ, Ryde IT, Yanai J. Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model. Neurotoxicol Teratol 2008;30(5):433-439.

(18) Ben-Shaanan TL, Ben-Hur T, Yanai J. Transplantation of neural progenitors enhances production of endogenous cells in the impaired brain. Mol Psychiatry 2008;13(2):222-231.

(19) Katz S, Ben-Hur T, Ben-Shaanan TL, Yanai J. Reversal of heroin neurobehavioral teratogenicity by grafting of neural progenitors. J Neurochem 2008;104(1):38-49.

(20) Yanai J, Dotan S, Goz R, Pinkas A, Seidler FJ, Slotkin TA, et al. Exposure of developing chicks to perfluorooctanoic acid induces defects in prehatch and early posthatch development. J Toxicol Environ Health Part A Curr Iss 2008;71(2):131-133.

(21) Huleihel R, Yanai J. Disruption of the development of cholinergic-induced translocation/ activation of PKC isoforms after prenatal heroin exposure. Brain Res Bull 2006;69(2):174-181.

(22) Yanai J, Ben-Shaanan TL, Haimovitch H, Katz S, Kazma M. Mechanism-based approaches for the reversal of drug neurobehavioral teratogenicity. Ann New York Acad Sci 2006;1074:659-671.

(23) Wormser U, Izrael M, Van Der Zee EA, Brodsky B, Yanai J. A chick model for the mechanisms of mustard gas neurobehavioral teratogenicity. Neurotoxicol Teratol 2005;27(1):65-71.

(24) Beer A, Slotkin TA, Seidler FJ, Aldridge JE, Yanai J. Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital. Neuropsychopharmacology 2005;30(1):156-165.

(25) Izrael M, Van Der Zee EA, Slotkin TA, Yanai J. Cholinergic synaptic signaling mechanisms underlying behavioral teratogenicity: Effects of nicotine, chlorpyrifos, and heroin converge on protein kinase C translocation in the intermedial part of the hyperstriatum ventrale and on imprinting behavior in an avian model. J Neurosci Res 2004;78(4):499-507.

(26) Yaniv SP, Naor Z, Yanai J. Prenatal heroin exposure alters cholinergic receptor stimulated activation of the PKCβII and PKCγ isoforms. Brain Res Bull 2004;63(4):339-349.

(27) Vatury O, Barg J, Slotkin TA, Yanai J. Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure. Brain Res Bull 2004;63(1):25-32.

(28) Yanai J, Beer A, Huleihel R, Izrael M, Katz S, Levi Y, et al. Convergent effects on cell signaling mechanisms mediate the actions of different neurobehavioral teratogens: Alterations in cholinergic regulation of protein kinase C in chick and avian models. Ann New York Acad Sci 2004;1025:595-601.

(29) Slotkin TA, Seidler FJ, Yanai J. Heroin neuroteratogenicity: Delayed-onset deficits in catecholaminergic synaptic activity. Brain Res 2003;984(1-2):189-197.

(30) Yanai J, Huleihel R, Izrael M, Metsuyanim S, Shahak H, Vatury O, et al. Functional changes after prenatal opiate exposure related to opiate receptors' regulated alterations in cholinergic innervation. Int J Neuropsychopharmacol 2003;6(3):253-265.

(31) Shahak H, Slotkin TA, Yanai J. Alterations in PKCγ in the mouse hippocampus after prenatal exposure to heroin: A link from cell signaling to behavioral outcome. Dev Brain Res 2003;140(1):117-125.

(32) Yanai J, Vatury O, Slotkin TA. Cell signaling as a target and underlying mechanism for neurobehavioral teratogenesis. Ann New York Acad Sci 2002;965:473-478.

(33) Slotkin TA, Seidler FJ, Yanai J. Heroin neuroteratogenicity: Targeting adenylyl cyclase as an underlying biochemical mechanism. Dev Brain Res 2001;132(1):69-79.

(34) Golani I, Weizman A, Leschiner S, Spanier I, Eckstein N, Limor R, et al. Hormonal regulation of peripheral benzodiazepine receptor binding properties is mediated by subunit interaction. Biochemistry 2001;40(34):10213-10222.

(35) Steingart RA, Silverman WF, Barron S, Slotkin TA, Awad Y, Yanai J. Neural grafting reverses prenatal drug-induced alterations in hippocampal PKC and related behavioral deficits. Dev Brain Res 2000;125(1-2):9-19.

(36) Steingart RA, Abu-Roumi M, Newman ME, Silverman WF, Slotkin TA, Yanai J. Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: Cellular mechanisms and the reversal of deficits by neural grafts. Dev Brain Res 2000;122(2):125-133.

(37) Yanai J, Steingart RA, Snapir N, Gvaryahu G, Rozenboim I, Katz A. The relationship between neural alterations and behavioral deficits after prenatal exposure to heroin. Ann New York Acad Sci 2000;914:402-411.

(38) Langerman L, Steingart RA, Margolis A, Yanai J. A method of reducing the opioid withdrawal intensity using progressively increasing doses of naloxone. J Pharmacol Toxicol Methods 1999;42(3):115-119.

(39) Weiss S, Sawa GH, Abdeen Z, Yanai J. Substance abuse studies and prevention efforts among Arabs in the 1990s in Israel, Jordan and the Palestinian Authority - A literature review. Addiction 1999;94(2):177-198.

(40) Belcheva MM, Bohn LM, Ho MT, Johnson FE, Yanai J, Barron S, et al. Brain opioid receptor adaptation and expression after prenatal exposure to buprenorphine. Dev Brain Res 1998;111(1):35-42.

(41) Steingart RA, Barg J, Maslaton J, Nesher M, Yanai J. Pre- and postsynaptic alterations in the septohippocampal cholinergic innervations after prenatal exposure to drugs. Brain Res Bull 1998;46(3):203-209.

(42) Yanai J, Abu-Roumi M, Silverman WF, Steingart RA. Neural grafting as a tool for the study and reversal of neurobehavioral birth defects. Pharmacol Biochem Behav 1996;55(4):673-681.

(43) Schreiber S, Backer MM, Yanai J, Pick CG. The antinociceptive effect of fluvoxamine. Eur Neuropsychopharmacol 1996;6(4):281-284.

(44) Tsur I, Harmelin A, Dvir I, Yanai J. Meningoencephalitis and brain abscessation due to Escherichia coli in a 2 week old alpaca cria. Austr Vet J 1996;74(6):437-438.

(45) Abu-Roumi M, Newman ME, Yanai J. Inositol phosphate formation in mice prenatally exposed to drugs: Relation to muscarinic receptors and postreceptor effects. Brain Res Bull 1996;40(3):183-186.

(46) Zahalka EH, Yanai J, Rehavi M, Newman ME. Alterations in hippocampal hemicholinium-3 binding and related behavioural and biochemical changes after prenatal phenobarbitone exposure. Psychopharmacology 1995;122(1):44-50.

(47) Zamir I, Yanai J. GTPase activity in mouse hippocampus membranes following prenatal exposure to heroin and phenobarbital. Biochem Pharmacol 1995;50(1):127-130.

(48) Yanai J, Silverman WF, Shamir D. An avian model for the reversal of 6-hydroxydopamine induced rotating behaviour by neural grafting. Neurosci Lett 1995;187(3):153-156.

(49) Yanai J, Doetchman T, Laufer N, Maslaton J, Mor-Yosef S, Safran A, et al. Embryonic cultures but not embryos transplanted to the mouse's brain grow rapidly without immunosuppression. Int J Neurosci 1995;81(3-4):21-26.

(50) Yanai J, Pick CG. Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis. Brain Res Bull 1995;38(1):93-98.

(51) Yanai J, Shaanani R, Pick CG. Altered brain sensitivity to ethanol in mice after MPTP treatment. Alcohol 1995;12(2):127-130.

(52) Yanai J, Abu-Roum M, Barg J, Vogel Z, Steingart R. Behavioral deficits and related septohippocampal cholinergic alterations after prenatal exposure to heroin. Regul Pept 1994;53(SUPPL. 1):S279-S280.

(53) Yanai J, Weiss S. Drug abuse primary prevention Research and programs among jewish youth in Israel: A review. Drugs Educ Prev Policy 1994;1(1):49-58.

(54) Rogel-Fuchs Y, Zahalka EA, Yanai J. Reversal of early phenobarbital-induced cholinergic and related behavioral deficits by neuronal grafting. Brain Res Bull 1994;33(3):273-279.

(55) Shye S, Yanai J, Pick CG. Directional consistency: Determinant of learned maze performance of five mice strains. Behav Processes 1994;32(2):117-131.

(56) Pick CG, Weizman A, Fares F, Gavish M, Kanner BI, Yanai J. Hippocampal γ-aminobutyric acid and benzodiazepine receptors after early phenobarbital exposure. Dev Brain Res 1993;74(1):111-116.

(57) Zahalka EA, Seidler FJ, Lappi SE, Yanai J, Slotkin TA. Differential development of cholinergic nerve terminal markers in rat brain regions: implications for nerve terminal density, impulse activity and specific gene expression. Brain Res 1993;601(1-2):221-229.

(58) Yanai J, Rogel-Fuchs Y, Pick CG, Slotkin T, Seidler FJ, Zahalka EA, et al. Septohippocampal cholinergic changes after destruction of the A10-septal dopaminergic pathways. Neuropharmacology 1993;32(2):113-117.

(59) Pick CG, Weizman A, Fares F, Gavish M, Kanner BI, Yanai J. Erratum: Hippocampal γ-aminobutyric acid and benzodiazepine receptors after early phenobarbital exposure (Developmental Brain Research, 74 (1993) (111-116)). Dev Brain Res 1993;75(2):301.

(60) Zahalka EA, Seidler FJ, Yanai J, Slotkin TA. Fetal nicotine exposure alters ontogeny of M1-receptors and their link to G-proteins. Neurotoxicol Teratol 1993;15(2):107-115.

(61) Pick CG, Cooperman M, Trombka D, Rogel-Fuchs Y, Yanai J. Hippocampal cholinergic alterations and related behavioral deficits after early exposure to ethanol. Int J Dev Neurosci 1993;11(3):379-385.

(62) Yanai J, Avraham Y, Levy S, Maslaton J, Pick CG, Rogel-Fuchs Y, et al. Alterations in septohippocampal cholinergic innervations and related behaviors after early exposure to heroin and phencyclidine. Dev Brain Res 1992;69(2):207-214.

(63) Yanai J, Shamir D, Silverman WF. Reversal of Rotating Behavior in the Domestic Fowl by Neural Grafting. J Neural Transplant Plast 1992;3(4):218-218.

(64) Yanai J, Pick CG, Rogel-Fuchs Y, Zahalka EA. Alterations in hippocampal cholinergic receptors and hippocampal behaviors after early exposure to nicotine. Brain Res Bull 1992;29(3-4):363-368.

(65) Zahalka EA, Seidler FJ, Lappi SE, Mccook EC, Yanai J, Slotkin TA. Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: Differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding. Neurotoxicol Teratol 1992;14(6):375-382.

(66) Rogel-Fuchs Y, Newman ME, Trombka D, Zahalka EA, Yanai J. Hippocampal cholinergic alterations and related behavioral deficits after early exposure to phenobarbital. Brain Res Bull 1992;29(1):1-6.

(67) Laviola G, Pick CG, Yanai J, Alleva E. Eight-arm maze performance, neophobia, and hippocampal cholinergic alterations after prenatal oxazepam in mice. Brain Res Bull 1992;29(5):609-616.

(68) Tal E, Nir I, Kalman R, Yanai J. Cyclohexyladenosine reduces MPTP induced tremor in dogs. Int J Neurosci 1990;55(2-4):125-128.

(69) Fares F, Weizman A, Pick CG, Yanai J, Gavish M. Effect of prenatal and neonatal chronic exposure to phenobarbital on central and peripheral benzodiazepine receptors. Brain Res 1990;506(1):115-119.

(70) Gaathon A, Tzur M, Fishman RHB, Yanai J. Thyroxin response to TRH in developing and adult mice. Neuroendocrinol Lett 1990;12(1):59-64.

(71) Yanai J, Fares F, Gavish M, Greenfeld Z, Katz Y, Marcovici BG, et al. Neural and behavioral alterations after early exposure to phenobarbital. Neurotoxicology 1989;10(3):543-554.

(72) Weizman A, Fares F, Pick CG, Yanai J, Gavish M. Chronic phenobarbital administration affects GABA and benzodiazepine receptors in the brain and periphery. Eur J Pharmacol 1989;169(2-3):235-240.

(73) Yanai J, Laxer U, Pick CG, Trombka D. Dopaminergic denervation reverses behavioral deficits induced by prenatal exposure to phenobarbital. Dev Brain Res 1989;48(2):255-261.

(74) Pick CG, Yanai J. Studies into the mechanisms of strain differences in hippocampus-related behaviors. Behav Genet 1989;19(2):315-325.

(75) H.B. Fishman R, Ornoy A, Yanai J. Correlated ultrastructural damage between cerebellum cells after early anticonvulsant treatment in mice. Int J Dev Neurosci 1989;7(1):15-26.

(76) Rosselli-Austin L, Yanai J. Neuromorphological changes in mouse olfactory bulb after neonatal exposure to phenobarbital. Neurotoxicol Teratol 1989;11(3):227-230.

(77) Yanai J, Guttman R, Stern E. Genotype-treatment interaction in response of mice to early barbiturate administration. Neonatology 1989;56(2):109-116.

(78) Kaspi A, Yanai J, Pick CG, Mann G. Entrapment of the distal suprascapular nerve - An anatomical study. Int Orthop 1988;12(4):273-275.

(79) Yanai J, Pick CG. Neuron transplantation reverses phenobarbital-induced behavioral birth defects in mice. Int J Dev Neurosci 1988;6(5):409-416.

(80) Yanai J, Pick CG. Studies on noradrenergic alterations in relation to early phenobarbital-induced behavioral changes. Int J Dev Neurosci 1987;5(4):337-344.

(81) Pick CG, Statter M, Shachar DB, Youdim MBH, Yanai J. Normal zinc and iron concentrations in mice after early exposure to phenobarbital. Int J Dev Neurosci 1987;5(5-6):391-398.

(82) Fishman RHB, Feigenbaum JJ, Iser-Strenger C, Yanai J. Diethystilbesterol counteracts barbiturate narcosis and hypothermia in Male mice. Int J Neurosci 1987;32(3-4):845-852.

(83) Bergman A, Niv D, David MP, Yanai J. Barbiturate narcosis and estrogen levels in women. Gynecol Obstet Invest 1987;23(3):167-171.

(84) Bergman A, McCarthy TA, Ballard CA, Yanai J. Role of the Q-tip test in evaluating stress urinary incontinence. J REPROD MED OBSTET GYNECOL 1987;32(4):273-275.

(85) Yanai J, Pick CG, Weinstein D, McRae-Degueurce A. The use of brain tissue transplantation in neuroteratological studies. Neurotoxicology 1986;7(2):141-146.

(86) Iser-Strenger C, Yanai J. Alterations in mice dopamine characteristics after early exposure to phenobarbital. Dev Brain Res 1986;30(1):57-65.

(87) Iser-Strenger C, Yanai J. Alterations in mice dopamine receptor characteristics after early exposure to phenobarbital. Dev Brain Res 1986;30(1):57-65.

(88) Yanai J, Pick CG, Iser-Strenger C. Chronic treatment with haloperidol affect the response of the brain to pentobarbital. Neuropharmacology 1986;25(8):943-945.

(89) Yanai J. Implications of changes in apomorphine-induced hypothermia after prenatal exposure to phenobarbital. Alcohol Drug Res 1985;6(1):49-56.

(90) Yanai J, Sze PY, Iser C, Melamed E. Studies on brain monoamine neurotransmitters in mice after prenatal exposure to barbiturate. Pharmacol Biochem Behav 1985;23(2):215-219.

(91) Yanai J, Wanich A. Prenatal versus neonatal long-term effect of phenobarbital on mouse microsomal drug-oxidizing system. Neonatology 1985;48(5):269-273.

(92) Kleinberger N, Yanai J. Early phenobarbital-induced alterations in hippocampal acetylcholinesterase activity and behavior. Dev Brain Res 1985;22(1):113-123.

(93) Pick CG, Yanai J. Long term reduction in eight arm maze performance after early exposure to phenobarbital. Int J Dev Neurosci 1985;3(3):223-227.

(94) Feigenbaum JJ, Yanai J. Implications of dopamine agonist-induced hypothermia following increased density of dopamine receptors in the mouse. Neuropharmacology 1985;24(8):735-741.

(95) Yanai J, Waknin S. Comparison of the effects of barbiturate and ethanol given to neonates on the cerebellar morphology. Acta Anat 1985;123(3):145-147.

(96) Yanai J, Fishman RHB, Mittleman L. Ascorbic acid effect on ethanol sensitivity via possible dopaminergic mediation. SUBST ALCOHOL ACTIONS MISUSE 1984;5(4):169-174.

(97) Feigenbaum JJ, Yanai J. Normal and abnormal determinants of dopamine receptor ontogeny in the central nervous system. Prog Neurobiol 1984;23(3):191-225.

(98) Yanai J, Fishman RHB. Resistance to barbiturate is changed by developmental alteration of dopamine receptor sensitivity. Int J Dev Neurosci 1984;2(1):61-64.

(99) Pick CG, Yanai J. Long-term reduction in spontaneous alternations after early exposure to phenobarbital. Int J Dev Neurosci 1984;2(3):223-228.

(100) Feigenbaum JJ, Yanai J, Iser C, Klawans H. Effect of naloxone on dopamine uptake and release in vitro in the striatum. Neuropsychobiology 1984;11(2):94-97.

(101) Feigenbaum J, Yanai J. The role of dopaminergic mechanisms in mediating the central behavioral effects of morphine in rodents. Neuropsychobiology 1984;11(2):98-105.

(102) Yanai J. Genetic factors in drug neuroteratogenicity. SUBST ALCOHOL ACTIONS MISUSE 1983;4(1):19-30.

(103) Yanai J, Sze PY. Adrenal glucocorticoids as a required factor in barbitura-induced changes in functional tolerance and brainstem tryptophan hydroxylase. Brain Res 1983;269(2):297-302.

(104) Yanai J, Sze PY. Isolation reduces midbrain tryptophan hydroxylase activity in mice. Psychopharmacology 1983;80(3):284-285.

(105) Feigenbaum JJ, Yanai J, Klawans HL. The comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced increases in locomotor acitivity. J Neural Transmission 1983;57(1-2):27-37.

(106) Pick CG, Yanai J. Eight arm maze for mice. Int J Neurosci 1983;21(1-2):63-66.

(107) Fishman RHB, Feigenbaum JJ, Yanai J, Klawans HL. The relative importance of dopamine and norepinephrine in mediating locomotor activity. Prog Neurobiol 1983;20(1-2):55-88.

(108) Yanai J, Feigenbaum JJ, Bannet J. Supersensitivity of dopaminergic receptors diminishes sensitivity to ethanol narcosis. Res Commun Subst Abuse 1983;4(3):263-266.

(109) Feigenbaum J, Yanai J, Moon B, Klawans H. Effect of naloxone and morphine on dopamine agonist-induced stereotypy in rats and guinea pigs. Neuropharmacology 1983;22(12 PART 2):1369-1376.

(110) Yanai J, Feigenbaum JJ. Apomorphine may prevent death due to barbiturate overdose in mice. Res Commun Subst Abuse 1983;4(4):343-346.

(111) Feigenbaum JJ, Yanai J, Klawans HL. Possible dopamine agonist properties of quipazine maleate. Int J Neurosci 1983;18(3-4):205-210.

(112) Feigenbaum J, Yanai J. Differential catecholamine uptake inhibition as a possible mode of action of D-amphetamine induced locomotor activity. Res Commun Chem Pathol Pharmacol 1983;39(2):349-352.

(113) Weidenfeld J, Siegel RA, Yanai J. Effect of phenobarbital on in vitro aromatization of testosterone to estradiol by adult male mice brain. J Steroid Biochem 1983;18(2):201-203.

(114) Fishman RHB, Yanai J. Long-lasting effects of early barbiturates on central nervous system and behavior. Neurosci Biobehav Rev 1983;7(1):19-28.

(115) Fishman RHB, Ornoy A, Yanai J. Ultrastructural evidence of long-lasting cerebellar degeneration after early exposure to phenobarbital in mice. Exp Neurol 1983;79(1):212-222.

(116) Feigenbaum J, Yanai J, Klawans HL, Chatterton R. The combined effect of quipazine and haloperidol on plasma prolactin release. Int J Neurosci 1983;18(1-2):37-40.

(117) Yanai J, Bergman A, Feigenbaum JJ. Genetic factors influencing neurosensitivity to early phenobarbital administration in mice. Acta Anat 1983;115(1):40-46.

(118) Bergman A, Yanai J, Weiss J, Bell D, David MP. Acceleration of wound healing by topical application of honey. An animal model. Am J Surg 1983;145(3):374-376.

(119) Feigenbaum JJ, Yanai J, Moon BH, Klawans HL. Morphine may not produce true catalepsy. Int J Neurosci 1983;18(3-4):199-203.

(120) Feigenbaum JJ, Yanai J. Evidence for the involvement of central dopaminergic receptors the acute and chronic effects induced by barbiturates. Neuropsychobiology 1983;9(2-3):83-87.

(121) Sze PY, Feigenbaum JJ, Yanai J. Adrenal glucocorticoids as a required factor in the development of ethanol tolerance in mice. Neuropsychobiology 1983;9(4):207-210.

(122) Feigenbaum JJ, Moon BH, Catterton R, Yanai J, Klawans HL. Haloperidol-induced plasma prolactin release: Sensitivity, reliability, and comparison to haloperidol antagonism of dopamine agonist-induced stereotyped behavior in the rat. Psychopharmacology 1982;78(4):383-384.

(123) Yanai J, Feigenbaum JJ, Fishman RHB. Lessened sensitivity to apomorphine induced climbing behavior in mice following neonatal exposure to phenobarbital. Neurobehav Toxicol Teratol 1982;4(5):535-538.

(124) Feigenbaum JJ, Fishman RHB, Yanai J. Mechanisms of dopamine antagonism by morphine in rodents. SUBST ALCOHOL ACTIONS MISUSE 1982;3(6):307-324.

(125) Feigenbaum JJ, Yanai J, Klawans HL. The comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced locomotor activity. J Neural Transmission 1982;54(3-4):145-151.

(126) Feigenbaum J, Yanai J, Moon B, Klawans H. The effect of naloxone on D-amphetamine induced locomotor activity. Res Commun Subst Abuse 1982;3(3):379-382.

(127) Yanai J, Iser C, Feigenbaum JJ. Changes in striatal dopaminergic behavior after early exposure to barbiturate. Behav Genet 1982;12(6):603.

(128) Yanai J, Woolf M, Feigenbaum JJ. Morphological alterations in the medial preoptic area after prenatal administration of phenobarbital. Acta Anat 1982;114(4):347-354.

(129) Feigenbaum J, Yanai J, Blass R. Possible DA agonist properties of naloxone. Int J Neurosci 1982;17(3):139-144.

(130) Weidenfeld J, Schiller H, Yanai J. Effect of early exposure to phenobarbital on in vitro aromatization of testosterone by neonatal male mice brain. Neuroendocrinol Lett 1982;4(6):355-359.

(131) Fishman RHB, Ornoy A, Yanai J. Ultrastructural evidence of cerebellar degeneration after early exposure to phenytoin and/or phenobarbital (Phb) in mice. Teratology 1982;26(3).

(132) Yanai J, Woolf M, Feigenbaum JJ. Autoradiographic study of phenobarbital's effect on development of the central nervous system. Exp Neurol 1982;78(2):437-449.

(133) Fishman RHB, Gaathon A, Yanai J. Early barbiturate treatment eliminates peak serum thyroxine levels in neonatal mice and produces ultrastructural damage in the brains of adults. Dev Brain Res 1982;5(2):202-205.

(134) Fishman RH, Batushansky, Ornoy A, Yanai J. Ultrastructural cerebellar degeneration in mice following early exposure to phenobarbital (PhB). Teratology 1982;25(1):15A-16A.

(135) Yanai J, Sze PY. Accelerated acquisition of ethanol tolerance in isolated mice. Neuropsychobiology 1982;8(3):135-139.

(136) Feigenbaum JJ, Yanai J, Blass RB. The role of dopamine and norepinephrine uptake inhibition in mediating the central effects of d-amphetamine in vivo. Res Commun Chem Pathol Pharmacol 1982;35(2):333-335.

(137) Feigenbaum JJ, Yanai J, Blass RB, Moon B, Klawans H. The effect of drugs altering striatal dopamine levels on apomorphine induced stereotypy. Pharmacol Biochem Behav 1982;16(2):235-240.

(138) Menashi M, Ornoy A, Yanai J. Transplacental effects of methylmercury chloride in mice with specific emphasis on the audiogenic seizure response. Dev Neurosci 1982;5(2-3):216-221.

(139) Bergman A, Feigenbaum JJ, Yanai J. Neuronal losses in mice following both prenatal and neonatal exposure to phenobarbital. Cells Tissues Organs 1982;114(2):185-192.

(140) Yanai J. Comparison of early barbiturate and ethanol effects on the CNS. SUBST ALCOHOL ACTIONS MISUSE 1981;2(2):79-91.

(141) Yanai J, Bergman A, Iser C. Barbiturate sensitivity of developing neurons in mice. Teratology 1981;24(2).

(142) Yanai J, Iser C. Stereologic study of Purkinje cells in mice after early exposure to phenobarbital. Exp Neurol 1981;74(3):707-716.

(143) Yanai J, Woolf M. Dendritic changes in Purkinje cells after early exposure to phenobarbital. Teratology 1981;23(2):70A-71A.

(144) Yanai J, Bergman A. Neuronal deficits after neonatal exposure to phenobarbital. Exp Neurol 1981;73(1):199-208.

(145) Yanai J, Bergman A, Shafer R, Yedwab G, Tabakoff B. Audiogenic seizures and neuronal deficits following early exposure to barbiturate. Dev Neurosci 1981;4(5):345-350.

(146) Belmaker RH, Bannet J, Brecher-Fride E, Yanai J, Ebstein RP. The effect of haloperidol feeding on dopamine receptor number in ten mouse strains. Clin Genet 1981;19(5):353-356.

(147) Kuprys R, Sridaran R, Yanai J. Hormonal status of mice treated prenatally with phenobarbital (PB). PHARMACOLOGIST 1981;23(3).

(148) Yanai J, Feigenbaum JJ. Lessened sensitivity to apomorphine induced hypothermia following prenatal exposure to phenobarbital. IRCS Med Sci 1981;9(10):965.

(149) Yanai J, Tabakoff B. Altered sensitivity to ethanol following prenatal exposure to barbiturate. Psychopharmacology 1980;68(3):301-303.

(150) Yanai J, Tabakoff B. Prenatal exposure to phenobarbital decreases brain sensitivity to ethanol. Drug Alcohol Depend 1980;6(1-2):49-50.

(151) Menashi M, Yanai J, Ornoy A. Barbiturate teratogenicity: An unsettled question. Isr J Med Sci 1980;16(7):558-559.

(152) Yanai J, Bergman B. Neuronal deficits following early exposure to phenobarbital. Teratology 1980;21(2).

(153) Bergman A, Rosselli-Austin L, Yedwab G, Yanai J. Neuronal deficits in mice following phenobarbital exposure during various periods in fetal development. Cells Tissues Organs 1980;108(3):370-373.

(154) Yanai J, Ginsburg BE. The relative contribution of pre- and neonatal ethanol administration to changes in mice behavior. Arch Int Pharmacodyn Ther 1979;241(2):235-244.

(155) Yanai J, Tabakoff B. Increased tolerance in mice following prenatal exposure to barbiturate. Psychopharmacology 1979;64(3):325-327.

(156) Yanai J. Delayed maturation of the male cerebral cortex in rats. Cells Tissues Organs 1979;104(3):335-339.

(157) Yanai J. Increased tolerance in mice following prenatal exposure to phenobarbital. Teratology 1979;19(2).

(158) Tabakoff B, Yanai J. Cortexolone antagonizes development of alcohol tolerance in mice. Psychopharmacology 1979;64(1):123-124.

(159) Yanai J. Strain and sex differences in the rat brain. Cells Tissues Organs 1979;103(2):150-158.

(160) Yanai J, Rosselli-Austin L, Tabakoff B. Neuronal deficits in mice following prenatal exposure to phenobarbital. Exp Neurol 1979;64(2):237-244.

(161) Mason ST, Corcoran ME, Tabakoff B, Yanai J, Ritzmann RF. Noradrenaline and seizures. Science 1979;203(4386):1265-1266.

(162) Yanai J, Rosselli-Austin L. Normal homing behavior in infant rats despite extensive olfactory bulb granule cell losses. Behav Biol 1978;24(4):539-544.

(163) Tabakoff B, Yanai J, Ritzmann RF. Brain noradrenergic systems as a prerequisite for developing tolerance to barbiturates. Science 1978;200(4340):449-451.

(164) Yanai J, Tabakoff B. Long lasting metabolic changes in mice following prenatal exposure to barbiturate. Isr J Med Sci 1978;14(9):1003.

(165) Tabakoff B, Yanai J, Ritzmann RF. Involvement of the noradrenergic (NE) systems in development of barbiturate tolerance. Behav Genet 1978;8(1):115-116.

(166) Yanai J, Ginsburg BE. A Developmental Study of Ethanol Effect on Behavior and Physical Development in Mice. Alcohol Clin Exp Res 1977;1(4):325-333.

(167) Tabakoff B, Ritzmann RF, Yanai J. Tolerance to sedative hypnotics, memory and noradrenergic (NE) systems. Fed Proc 1977;36(3).

(168) Yanai J, Ginsburg BE. Long term reduction of male agonistic behavior in mice following early exposure to ethanol. Psychopharmacology 1977;52(1):31-34.

(169) Sze PY, Yanai J, Ginsburg BE. Effects of early ethanol input on the activities of ethanol-metabolizing enzymes in mice. Biochem Pharmacol 1976;25(2):215-217.

(170) Yanai J, Ginsburg BE. Increased sensitivity to chronic ethanol in isolated mice. Psychopharmacology 1976;46(2):185-189.

(171) Yanai J, Ginsburg BE. Audiogenic seizures in mice whose parents drank alcohol. J Stud Alcohol 1976;37(11):1564-1571.

(172) Yanai J, Ginsburg BE. Long-term effects of early ethanol on predatory behavior in inbred mice. Physiol Psychol 1976;4(4):409-411.

(173) Yanai J, Ginsburg BE. Suppressant Effects of Alcohol on Audiogenic Seizures. Epilepsia 1975;16(3):491-496.

(174) Yanai J, Sze PY, Ginsburg BE. Effects of Aminergic Drugs and Glutamic Acid on Audiogenic Seizures Induced by Early Exposure to Ethanol. Epilepsia 1975;16(1):67-71.

(175) Sze PY, Yanai J, Ginsburg BE. Adrenal glucocorticoids as a required factor in the development of ethanol withdrawal seizures in mice. Brain Res 1974;80(1):155-159.

(176) Yanai J, McClearn GE. Assortative mating in mice. II. Strain differences in female mating preference, male preference, and the question of possible sexual selection. Behav Genet 1973;3(1):65-74.

(177) Yanai J, McClearn GE. Assortative mating in mice. III. Genetic determination of female mating preference. Behav Genet 1973;3(1):75-84.

(178) Yanai J, Mcclearn GE. Assortative mating in mice and the incest taboo. Nature 1972;238(5362):281-282.

(179) Yanai J, McClearn GE. Assortative mating in mice. I. Female mating preference. Behav Genet 1972;2(2-3):173-183.