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The Faculty of Medicine - Medical Neurobiology: Melamed Ze'ev


Last updated December 2021 - Medical Neurobiology

List of Publications

(1) Sidibé H, Khalfallah Y, Xiao S, Gómez NB, Fakim H, Tank EMH, et al. TDP-43 stabilizes G3BP1 mRNA: Relevance to amyotrophic lateral sclerosis/frontotemporal dementia. Brain 2021;144(11):3461-3476.

(2) Theunissen F, Anderton RS, Mastaglia FL, Flynn LL, Winter SJ, James I, et al. Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype. Front Aging Neurosci 2021;13.

(3) Glaich O, Parikh S, Bell RE, Mekahel K, Donyo M, Leader Y, et al. DNA methylation directs microRNA biogenesis in mammalian cells. Nat Commun 2019;10(1).

(4) Gasset-Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron 2019;102(2):339-357.e7.

(5) Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci 2019;22(2):180-190.

(6) Dror H, Donyo M, Atias N, Mekahel K, Melamed Z, Yannai S, et al. A network-based analysis of colon cancer Splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1. Genome Res 2016;26(4):541-553.

(7) Golan T, Messer AR, Amitai-Lange A, Melamed Z, Ohana R, Bell RE, et al. Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF. Mol Cell 2015;59(4):664-676.

(8) Melamed Z, Levy A, Ashwal-Fluss R, Lev-Maor G, Mekahel K, Atias N, et al. Alternative Splicing Regulates Biogenesis of miRNAs Located across Exon-Intron Junctions. Mol Cell 2013;50(6):869-881.

(9) Amit M, Sela N, Keren H, Melamed Z, Muler I, Shomron N, et al. Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene. BMC Mol Biol 2007;8.