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The Faculty of Medicine - Developmental Biology and Cancer Research: Ben-Zvi Ayal


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Ben-Zvi A, Liebner S. Developmental regulation of barrier- and non-barrier blood vessels in the CNS. J Intern Med (GBR) 2021.

(2) Licht T, Sasson E, Bell B, Grunewald M, Kumar S, Kreisel T, et al. Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes. eLife 2020;9:1-20.

(3) Bar O, Gelb S, Atamny K, Anzi S, Ben-Zvi A. Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer. Fluids Barriers CNS 2020;17(1).

(4) Lax N, Fainstein N, Nishri Y, Ben-Zvi A, Ben-Hur T. Systemic microbial TLR2 agonists induce neurodegeneration in Alzheimer's disease mice. J Neuroinflamm 2020;17(1).

(5) Corem N, Anzi S, Gelb S, Ben-Zvi A. Leptin receptor deficiency induces early, transient and hyperglycaemia-independent blood-brain barrier dysfunction. Sci Rep 2019;9(1).

(6) Stock AD, Der E, Gelb S, Huang M, Weidenheim K, Ben-Zvi A, et al. Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus. JCI Insight 2019;4(11).

(7) Nitzan K, Benhamron S, Valitsky M, Kesner EE, Lichtenstein M, Ben-Zvi A, et al. Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimer's Disease Mice. J Alzheimers Dis 2019;72(2):587-604.

(8) Gelb S, Stock AD, Anzi S, Putterman C, Ben-Zvi A. Mechanisms of neuropsychiatric lupus: The relative roles of the blood-cerebrospinal fluid barrier versus blood-brain barrier. J Autoimmun 2018;91:34-44.

(9) Stock AD, Ben-Zvi A, Putterman C. Pathogenesis of neuropsychiatric lupus. Dubois' Lupus Erythematosus and Related Syndromes; 2018. p. 317-323.

(10) Stock AD, Gelb S, Pasternak O, Ben-Zvi A, Putterman C. The blood brain barrier and neuropsychiatric lupus: new perspectives in light of advances in understanding the neuroimmune interface. Autoimmun Rev 2017;16(6):612-619.

(11) Andreone BJ, Chow BW, Tata A, Lacoste B, Ben-Zvi A, Bullock K, et al. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron 2017;94(3):581-594.e5.

(12) Almasi S, Ben-Zvi A, Lacoste B, Gu C, Miller EL, Xu X. Joint volumetric extraction and enhancement of vasculature from low-SNR 3-D fluorescence microscopy images. Pattern Recogn 2017;63:710-718.

(13) Hagan N, Ben-Zvi A. The molecular, cellular, and morphological components of blood-brain barrier development during embryogenesis. Semin Cell Dev Biol 2015;38:7-15.

(14) Almasi S, Xu X, Ben-Zvi A, Lacoste B, Gu C, Miller EL. A novel method for identifying a graph-based representation of 3-D microvascular networks from fluorescence microscopy image stacks. Med Image Anal 2015;20(1):208-223.

(15) Licht T, Dor-Wollman T, Ben-Zvi A, Rothe G, Keshet E. Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity. J Clin Invest 2015;125(3):1319-1328.

(16) Lacoste B, Comin CH, Ben-Zvi A, Kaeser PS, Xu X, Costa LF, et al. Sensory-Related Neural Activity Regulates the Structure of Vascular Networks in the Cerebral Cortex. Neuron 2014;83(5):1117-1130.

(17) Tata A, Stoppel DC, Hong S, Ben-Zvi A, Xie T, Gu C. An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling. J Cell Biol 2014;205(4):573-590.

(18) Gazit R, Mandal PK, Ebina W, Ben-Zvi A, Nombela-Arrieta C, Silberstein LE, et al. Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J Exp Med 2014;211(7):1315-1331.

(19) Ben-Zvi A, Lacoste B, Kur E, Andreone BJ, Mayshar Y, Yan H, et al. Mfsd2a is critical for the formation and function of the blood-brain barrier. Nature 2014;509(7501):507-511.

(20) Ben-Zvi A, Sweetat S, Behar O. Elimination of Aberrant DRG Circuitries in Sema3A Mutant Mice Leads to Extensive Neuronal Deficits. PLoS ONE 2013;8(7).

(21) Ben-Zvi A, Manor O, Schachner M, Yaron A, Tessier-Lavigne M, Behar O. The semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development. J Neurosci 2008;28(47):12427-12432.

(22) Ben-Zvi A, Ben-Gigi L, Yagil Z, Lerman O, Behar O. Semaphorin3A regulates axon growth independently of growth cone repulsion via modulation of TrkA signaling. Cell Signal 2008;20(3):467-479.

(23) Ben-Zvi A, Ben-Gigi L, Klein H, Behar O. Modulation of semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning. J Neurosci 2007;27(47):13000-13011.

(24) Lerman O, Ben-Zvi A, Yagil Z, Behar O. Semaphorin3A accelerates neuronal polarity in vitro and in its absence the orientation of DRG neuronal polarity in vivo is distorted. Mol Cell Neurosci 2007;36(2):222-234.

(25) Ben-Zvi A, Yagil Z, Hagalili Y, Klein H, Lerman O, Behar O. Semaphorin 3A and neurotrophins: A balance between apoptosis and survival signaling in embryonic DRG neurons. J Neurochem 2006;96(2):585-597.