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The Faculty of Medicine - Biochemistry and Molecular Biology: Nissim Lior

Researchers

 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Wu M-, Nissim L, Stupp D, Pery E, Binder-Nissim A, Weisinger K, et al. A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS). Nat Commun 2019;10(1).

(2) Lee G, Atia L, Lan B, Sharma Y, Nissim L, Wu M-, et al. Contact guidance and collective migration in the advancing epithelial monolayer. Connect Tissue Res 2018;59(4):309-315.

(3) Nissim L, Wu M-, Pery E, Binder-Nissim A, Suzuki HI, Stupp D, et al. Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy. Cell 2017;171(5):1138-1150.e15.

(4) Morel M, Shtrahman R, Rotter V, Nissim L, Bar-Ziv RH. Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by Synthetic circuits. Proc Natl Acad Sci U S A 2016;113(29):8133-8138.

(5) Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK. Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells. Mol Cell 2014;54(4):698-710.

(6) Nissim L, Bar-Ziv RH. A tunable dual-promoter integrator for targeting of cancer cells. Mol Syst Biol 2010;6.

(7) Nissim L, Beatus T, Bar-Ziv R. An autonomous system for identifying and governing a cell's state in yeast. Phys Biol 2007;4(3):154-163.

(8) Matas D, Milyavsky M, Shats I, Nissim L, Goldfinger N, Rotter V. p53 is a regulator of macrophage differentiation. Cell Death Differ 2004;11(4):458-467.

(9) Peller S, Frenkel J, Lapidot T, Kahn J, Rahimi-Levene N, Yona R, et al. The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts. Oncogene 2003;22(30):4648-4655.