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The Faculty of Medicine - Biochemistry and Molecular Biology: Salton Maayan

Researchers

 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Petasny M, Bentata M, Pawellek A, Baker M, Kay G, Salton M. Splicing to Keep Cycling: The Importance of Pre-mRNA Splicing during the Cell Cycle. Trends Genet 2021;37(3):266-278.

(2) Drori A, Gammal A, Azar S, Hinden L, Hadar R, Wesley D, et al. Cb1r regulates soluble leptin receptor levels via chop, contributing to hepatic leptin resistance. eLife 2020;9:1-26.

(3) Raguz N, Heim A, Engal E, Wesche J, Merl-Pham J, Hauck SM, et al. JMJD6 regulates splicing of its own gene resulting in alternatively spliced isoforms with different nuclear targets. Int J Mol Sci 2020;21(18):1-15.

(4) Ben-Ami R, Klochendler A, Seidel M, Sido T, Gurel-Gurevich O, Yassour M, et al. Large-scale implementation of pooled RNA extraction and RT-PCR for SARS-CoV-2 detection. Clin Microbiol Infect 2020;26(9):1248-1253.

(5) Bentata M, Morgenstern G, Nevo Y, Kay G, Mizrahi AG, Temper M, et al. Splicing factor transcript abundance in saliva as a diagnostic tool for breast cancer. Genes 2020;11(8):1-12.

(6) Siam A, Baker M, Amit L, Regev G, Rabner A, Najar RA, et al. Regulation of alternative splicing by p300-mediated acetylation of splicing factors. RNA 2019;27(5):813-824.

(7) Wesche J, Kühn S, Kessler BM, Salton M, Wolf A. Protein arginine methylation: a prominent modification and its demethylation. Cell Mol Life Sci 2017;74(18):3305-3315.

(8) Salton M, Misteli T. Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy. Trends Mol Med 2016;22(1):28-37.

(9) Salton M, Kasprzak WK, Voss T, Shapiro BA, Poulikakos PI, Misteli T. Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing. Nat Commun 2015;6.

(10) Salton M, Voss TC, Misteli T. Identification by high-throughput imaging of the histone methyltransferase EHMT2 AS an epigenetic regulator of VEGFA alternative splicing. Nucleic Acids Res 2014;42(22):13662-13672.

(11) Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature 2011;480(7377):387-390.

(12) Salton M, Elkon R, Borodina T, Davydov A, Yaspo M-, Halperin E, et al. Matrin 3 binds and stabilizes mRNA. PLoS ONE 2011;6(8).

(13) Salton M, Lerenthal Y, Wang S-, Chen DJ, Shiloh Y. Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response. Cell Cycle 2010;9(8):1568-1576.