Skip to Main Content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

The Faculty of Medicine - Biochemistry and Molecular Biology: Shaulian Eitan


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Zahavi T, Maimon A, Kushnir T, Lange R, Berger E, Kornspan D, et al. Ras-Erk signaling induces phosphorylation of human TLE1 and downregulates its repressor function. Oncogene 2017;36(26):3729-3739.

(2) Anzi S, Shaulian E. Jun proteins and AP-1 in tumorigenesis. Molecular Oncology: Causes of Cancer and Targets for Treatment; 2015. p. 319-327.

(3) Blumberg A, Sailaja BS, Kundaje A, Levin L, Dadon S, Shmorak S, et al. Transcription factors bind negatively selected sites within human mtDNA genes. Genome Biolog Evol 2014;6(10):2634-2646.

(4) Sionov RV, Netzer E, Shaulian E. Differential regulation of FBXW7 isoforms by various stress stimuli. Cell Cycle 2013;12(22):3547-3554.

(5) Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012;8(4):445-544.

(6) Baruch K, Gur-Arie L, Nadler C, Koby S, Yerushalmi G, Ben-Neriah Y, et al. Metalloprotease type III effectors that specifically cleave JNK and NF-κB. EMBO J 2011;30(1):221-231.

(7) Galli F, Rossi M, D'Alessandra Y, De Simone M, Lopardo T, Haupt Y, et al. MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation. J Cell Sci 2010;123(14):2423-2433.

(8) Shaulian E. AP-1 - The Jun proteins: Oncogenes or tumor suppressors in disguise? Cell Signal 2010;22(6):894-899.

(9) Yogev O, Shaulian E. Jun proteins inhibit autophagy and induce cell death. Autophagy 2010;6(4):566-567.

(10) Yogev O, Goldberg R, Anzi S, Yogev O, Shaulian E. Jun proteins are starvation-regulated inhibitors of autophagy. Cancer Res 2010;70(6):2318-2327.

(11) Yogev O, Yogev O, Singer E, Shaulian E, Goldberg M, Fox TD, et al. Fumarase: A mitochondrial metabolic enzyme and a cytosolic/nuclear component of the dna damage response. PloS Biol 2010;8(3).

(12) Finkin S, Aylon Y, Anzi S, Oren M, Shaulian E. Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy. Oncogene 2008;27(32):4411-4421.

(13) Anzi S, Finkin S, Shaulian E. Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV. Cell Signal 2008;20(5):862-871.

(14) Yogev O, Saadon K, Anzi S, Inoue K, Shaulian E. DNA damage-dependent translocation of B23 and p19ARF is regulated by the Jun N-terminal kinase pathway. Cancer Res 2008;68(5):1398-1406.

(15) Yogev O, Anzi S, Inoue K, Shaulian E. Induction of transcriptionally active Jun proteins regulates drug-induced senescence. J Biol Chem 2006;281(45):34475-34483.

(16) Shaulian E. Transcription Factors: AP-1. Encyclopedia of Respiratory Medicine, Four-Volume Set; 2006. p. 251-257.

(17) Lerdrup M, Holmberg C, Dietrich N, Shaulian E, Herdegen T, Jäättelä M, et al. Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis. Biochim Biophys Acta Mol Cell Res 2005;1745(1):29-37.

(18) Shaulian E, Karin M. AP-1 as a regulator of cell life and death. Nature Cell Biol 2002;4(5):E131-E136.

(19) Karin M, Shaulian E. AP-1: Linking hydrogen peroxide and oxidative stress to the control of cell proliferation and death. IUBMB Life 2001;52(1-2):17-24.

(20) Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene 2001;20(19 REV. ISS. 2):2390-2400.

(21) Shaulian E, Schreiber M, Piu F, Beeche M, Wagner EF, Karin M. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 2000;103(6):897-908.

(22) Shaulian E, Karin M. Stress-induced JNK activation is independent of Gadd45 induction. J Biol Chem 1999;274(42):29595-29598.

(23) Ratziu V, Lalazar A, Wong L, Dang Q, Collins C, Shaulian E, et al. Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis. Proc Natl Acad Sci U S A 1998;95(16):9500-9505.

(24) Hosokawa K, Aharoni D, Dantes A, Shaulian E, Schere-levy C, Atzmon R, et al. Modulation of Mdm2 expression and p53-induced apoptosis in immortalized human ovarian granulosa cells. Endocrinology 1998;139(11):4688-4700.

(25) Friedman SL, Shaulian E, Littlewood T, Resnitzky D, Oren M. Resistance to p53-mediated growth arrest and apoptosis in Hep 3B hepatoma cells. Oncogene 1997;15(1):63-70.

(26) Shaulian E, Resnitzky D, Shifman O, Blandino G, Amsterdam A, Yayon A, et al. Induction of Mdm2 and enhancement of cell survival by bFGF. Oncogene 1997;15(22):2717-2725.

(27) Haupt Y, Rowan S, Shaulian E, Vousden KH, Oren M. Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Genes Dev 1995;9(17):2170-2183.

(28) Shaulian E, Haviv I, Shaul Y, Oren M. Transcriptional repression by the C-terminal domain of p53. Oncogene 1995;10(4):671-680.

(29) Telerman A, Tuynder M, Dupressoir T, Robaye B, Sigaux F, Shaulian E, et al. A model for tumor suppression using H-1 parvovirus. Proc Natl Acad Sci U S A 1993;90(18):8702-8706.

(30) Shaulian E, Zauberman A, Milner J, Davies EA, Oren M. Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation. EMBO J 1993;12(7):2789-2797.

(31) Shaulian E, Zauberman A, Ginsberg D, Oren M. Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding. Mol Cell Biol 1992;12(12):5581-5592.