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The Faculty of Medicine - Microbiology and Molecular Genetics: Rottem Shlomo


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Kornspan JD, Kosower NS, Vaisid T, Katzhandler J, Rottem S. Novel synthetic lipopeptides derived from Mycoplasma hyorhinis upregulate calpastatin in SH-SY5Y neuroblastoma cells and induce a neuroprotective effect against amyloid-β-peptide toxicity. FEMS Microbiol Lett 2021;367(10).

(2) Rottem S. Unique choline-containing phosphoglycolipids in Mycoplasma fermentans. Chem Phys Lipids 2016;194:94-100.

(3) Rottem S. Unique choline-containing phosphoglycolipids in Mycoplasma fermentans. Chem Phys Lipids 2015;191:61-67.

(4) Atalla H, Lysnyansky I, Raviv Y, Rottem S. Mycoplasma gallisepticum inactivated by targeting the hydrophobic domain of the membrane preserves surface lipoproteins and induces a strong immune response. PLoS ONE 2015;10(3).

(5) Kornspan JD, Tsur M, Tarshis M, Rottem S, Brenner T. Mycoplasma hyorhinis induces proinflammatory responses in mice lymphocytes. J Basic Microbiol 2015;55(5):679-684.

(6) Kornspan JD, Rottem S, Nir-Paz R. Cardiolipin synthetase is involved in antagonistic interaction (reverse CAMP phenomenon) of Mycoplasma species with Staphylococcus aureus beta-hemolysis. J Clin Microbiol 2014;52(5):1622-1628.

(7) Rechnitzer H, Rottem S, Herrmann R. Reconstitution of an active arginine deiminase pathway in mycoplasma pneumoniae M129. Infect Immun 2013;81(10):3742-3749.

(8) Kornspan JD, Ginsburg I, Rottem S. The oxidant scavenging capacity of the oral Mycoplasma salivarium. Arch Oral Biol 2013;58(10):1378-1384.

(9) Kornspan JD, Rottem S. Phospholipase A and glycerophosphodiesterase activities in the cell membrane of Mycoplasma hyorhinis. FEMS Microbiol Lett 2012;332(1):34-39.

(10) Elkind E, Vaisid T, Kornspan JD, Barnoy S, Rottem S, Kosower NS. Calpastatin upregulation in Mycoplasma hyorhinis-infected cells is promoted by the mycoplasma lipoproteins via the NF-κB pathway. Cell Microbiol 2012;14(6):840-851.

(11) Kornspan JD, Tarshis M, Rottem S. Adhesion and biofilm formation of Mycoplasma pneumoniae on an abiotic surface. Arch Microbiol 2011;193(11):833-836.

(12) Kornspan JD, Lysnyansky I, Kahan T, Herrmann R, Rottem S, Nir-Paz R. Genome analysis of a Mycoplasma hyorhinis strain derived from a primary human melanoma cell line. J Bacteriol 2011;193(17):4543-4544.

(13) Elkind E, Vaisid T, Kornspan JD, Barnoy S, Rottem S, Kosower NS. Neuroprotective effects of Mycoplasma hyorhinis against amyloid-β-peptide toxicity in SH-SY5Y human neuroblastoma cells are mediated by calpastatin upregulation in the mycoplasma-infected cells. Neurochem Int 2011;58(4):497-503.

(14) Rechnitzer H, Brzuszkiewicz E, Strittmatter A, Liesegang H, Lysnyansky I, Daniel R, et al. Genomic features and insights into the biology of Mycoplasma fermentans. Microbiology 2011;157(3):760-773.

(15) Kornspan JD, Tarshis M, Rottem S. Invasion of melanoma cells by Mycoplasma hyorhinis: Enhancement by protease treatment. Infect Immun 2010;78(2):611-617.

(16) Elkind E, Rechnitzer H, Vaisid T, Kornspan JD, Barnoy S, Rottem S, et al. Mycoplasma hyorhinis upregulates calpastatin and inhibits calpain-dependent proteolysis in SH-SY5Y neuroblastoma cells. FEMS Microbiol Lett 2010;304(1):62-68.

(17) Moussa A, Nir-Paz R, Rottem S. Binding of IgA by mycoplasma penetrans. Curr Microbiol 2009;58(4):360-365.

(18) Zeiman E, Tarshis M, Rottem S. Mycoplasma penetrans under nutritional stress: Influence on lipid and lipoprotein profiles and on the binding to and invasion of HeLa cells. FEMS Microbiol Lett 2008;287(2):243-249.

(19) Yavlovich A, Rechnitzer H, Rottem S. α-Enolase resides on the cell surface of Mycoplasma fermentans and binds plasminogen. Infect Immun 2007;75(12):5716-5719.

(20) Yavlovich A, Rottem S. Binding of host extracellular matrix proteins to Mycoplasma fermentans and its effect on adherence to, and invasion of HeLa cells. FEMS Microbiol Lett 2007;266(2):158-162.

(21) Rechnitzer H, Rottem S. Reconstituted proteolipid vesicles prepared from Mycoplasma fermentans membranes are able to bind and fuse with Molt-3 cells. Curr Microbiol 2006;53(4):293-297.

(22) Yavlovich A, Kohen R, Ginsburg I, Rottem S. The reducing antioxidant capacity of Mycoplasma fermentans. FEMS Microbiol Lett 2006;259(2):195-200.

(23) Rosenbluh J, Hariton-Gazal E, Dagan A, Rottem S, Graessmann A, Loyter A. Translocation of histone proteins across lipid bilayers and mycoplasma membranes. J Mol Biol 2005;345(2):387-400.

(24) Yavlovich A, Katzenell A, Tarshis M, Higazi AA-, Rottem S. Mycoplasma fermentans binds to and invades HeLa cells: Involvement of plasminogen and urokinase. Infect Immun 2004;72(9):5004-5011.

(25) Gazit R, Rechnitzer H, Achdout H, Katzenell A, Katz G, Markel G, et al. Recognition of Mycoplasma hyorhinis by CD99-Fc molecule. Eur J Immunol 2004;34(7):2032-2040.

(26) Yavlovich A, Tarshis M, Rottem S. Internalization and intracellular survival of Mycoplasma pneumoniae by non-phagocytic cells. FEMS Microbiol Lett 2004;233(2):241-246.

(27) Tarshis M, Yavlovich A, Katzenell A, Ginsburg I, Rottem S. Intracellular location and survival of Mycoplasma penetrans within HeLa cells. Curr Microbiol 2004;49(2):136-140.

(28) Rottem S. Interaction of mycoplasmas with host cells. Physiol Rev 2003;83(2):417-432.

(29) Rottem S. Choline-containing lipids in mycoplasmas. Microbes Infect 2002;4(9):963-968.

(30) Rottem S. Sterols and acylated proteins in mycoplasmas. Biochem Biophys Res Commun 2002;292(5):1289-1292.

(31) Ben-Menachem G, Byström T, Rechnitzer H, Rottem S, Rilfors L, Lindblom G. The physico-chemical characteristics of the phosphocholine-containing glycoglycerolipid MfGL-II govern the permeability properties of Mycoplasma fermentans. Eur J Biochem 2001;268(13):3694-3701.

(32) Ben-Menachem G, Mousa A, Brenner T, Pinto F, Zähringer U, Rottem S. Choline deficiency induced by Mycoplasma fermentans enhances apoptosis of rat astrocytes. FEMS Microbiol Lett 2001;201(2):157-162.

(33) Ben-Menachem G, Zähringer U, Rottem S. Erratum: The phospocholine motif in membranes of Mycoplasma fermentans strains (FEMS Microbiology Letters (2001) 199 (137-141) PII: S0378109701001732). FEMS Microbiol Lett 2001;201(1):119.

(34) Ben-Menachem G, Zähringer U, Rottem S. The phosphocholine motif in membranes of Mycoplasma fermentans strains. FEMS Microbiol Lett 2001;199(1):137-141.

(35) Yavlovich A, Higazi A-, Rottem S. Plasminogen binding and activation by Mycoplasma fermentans. Infect Immun 2001;69(4):1977-1982.

(36) Wagner F, Rottem S, Held H-, Uhlig S, Zähringer U. Ether lipids in the cell membrane of Mycoplasma fermentans. Eur J Biochem 2000;267(20):6276-6286.

(37) Rottem S, Yogev D. Mycoplasma interaction with eukaryotic cells. Subcell Biochem 2000;33:199-227.

(38) Rottem S, Naot Y. Subversion and exploitation of host cells by mycoplasmas. Trends Microbiol 1998;6(11):436-440.

(39) Ben-Menachem G, Rottem S, Tarshis M, Barash V, Brenner T. Mycoplasma fermentans glycolipid triggers inflammatory response in rat astrocytes. Brain Res 1998;803(1-2):34-38.

(40) Salman M, Borovsky Z, Rottem S. Mycoplasma penetrans infection of Molt-3 lymphocytes induces changes in the lipid composition of host cells. Microbiology 1998;144(12):3447-3454.

(41) Borovsky Z, Tarshis M, Zhang P, Rottem S. Protein kinase C activation and vacuolation in HeLa cells invaded by Mycoplasma penetrans. J Med Microbiol 1998;47(10):915-922.

(42) Zähringer U, Wagner F, Rietschel ET, Ben-Menachem G, Deutsch J, Rottem S. Primary structure of a new phosphocholine-containing glycoglycerolipid of Mycoplasma fermentans. J Biol Chem 1997;272(42):26262-26270.

(43) Ben-Menachem G, Wagner F, Zähringer U, Rietschel, Rottem S. Antibody response to MfGL-II, a phosphocholine-containing major lipid of Mycoplasma fermentans membranes. FEMS Microbiol Lett 1997;154(2):363-369.

(44) Sher T, Ehrlich Y, Rottem S. Mycoplasma in the spotlight of AIDS: Partial biochemical characterization of mycoplasma-derived components inducing TNFα secretion and blast transformation. Indian J Biochem Biophys 1997;34(1-2):6-10.

(45) Borovsky Z, Aner R, Rottem S. The 57-kilodalton phosphoprotein of Spiroplasma melliferum is autophosphorylated. Curr Microbiol 1997;34(1):33-37.

(46) Yan ZX, Andreev J, Rottem S, Meyer TF. Construction of a Mycoplasma penetrans expression library in E. coli using the two-phase expression system. Behring Inst Mitt 1997(98):99-102.

(47) Ben-Menachem G, Himmelreich R, Herrmann R, Aharonowitz Y, Rottem S. The thioredoxin reductase system of mycoplasmas. Microbiology 1997;143(6):1933-1940.

(48) Andreev J, Borovsky Z, Rosenshine I, Rottem S. Invasion of HeLa cells by Mycoplasma penetrans and the induction of tyrosine phosphorylation of a 145-kDa host cell protein. FEMS Microbiol Lett 1995;132(3):189-194.

(49) Salman M, Rottem S. The cell membrane of Mycoplasma penetrans: lipid composition and phospholipase A1 activity. Biochim Biophys Acta Biomembr 1995;1235(2):369-377.

(50) Deutsch J, Salman M, Rottem S. An Unusual Polar Lipid from the Cell Membrane of Mycoplasma fermentans. Eur J Biochem 1995;227(3):897-902.

(51) Shirazi I, Tarshis M, Rottem S. An arginine/ornithine exchange system in Spiroplasma melliferum. Microbiology 1995;141(9):2323-2328.

(52) Salman M, Deutsch I, Tarshis M, Naot Y, Rottem S. Membrane lipids of Mycoplasma fermentans. FEMS Microbiol Lett 1994;123(3):255-260.

(53) Tarshis M, Katzenel A, Rottem S. Use of merocyanine 540 and Hoechst 33258 for the selective killing of contaminating mycoplasmas in cell cultures. J Immunol Methods 1994;168(2):245-252.

(54) Shirazi I, Rottem S. Volume regulation in spiroplasma floricola: Evidence that Na+ is extruded by a Na+/H+ antiporter. Microbiology 1994;140(8):1899-1907.

(55) Olson LD, Renshaw CA, Rottem S, Boal JH. Arginine utilization by Mycoplasma fermentans is not regulated by glucose metabolism: A 13C-NMR study. FEMS Microbiol Lett 1993;108(1):47-51.

(56) Rottem S, Barile MF. Beware of mycoplasmas. Trends Biotechnol 1993;11(4):143-151.

(57) Shirvan MH, Rottem S. Ion pumps and volume regulation in mycoplasma. Subcell Biochem 1993;20:261-292.

(58) Tarshis M, Salman M, Rottem S. Cholesterol is required for the fusion of single unilamellar vesicles with Mycoplasma capricolum. Biophys J 1993;64(3):709-715.

(59) Salman M, Shirazi I, Tarshis M, Rottem S. Fusion of Spiroplasma floricola cells with small unilamellar vesicles is dependent on the age of the culture. J Bacteriol 1993;175(20):6652-6658.

(60) Hoischen C, Dijkstra A, Rottem S, Reizer J, Saier Jr. MH. Presence of protein constituents of the gram-positive bacterial phosphotransferase regulatory system in Acholeplasma laidlawii. J Bacteriol 1993;175(20):6599-6604.

(61) Rottem S, Dimitrov DS, Franzoso G, Salman M, Blumenthal R, Tarshis M, et al. Mycoplasma fermentans (Incognitus Strain) Cells Are Able to Fuse with T Lymphocytes. Clin Infect Dis 1993;17:S305-S308.

(62) Franzoso G, Dimitrov DS, Blumenthal R, Barile MF, Rottem S. Fusion of Mycoplasma fermentans strain incognitus with T-lymphocytes. FEBS Lett 1992;303(2-3):251-254.

(63) Borovsky Z, Sinnreich M, Rottem S. Palmitoylation of membrane proteins in Spiroplasma floricola. Curr Microbiol 1992;24(2):67-71.

(64) Salman M, Tarshis M, Rottem S. Fusion-mediated transfer of plasmids into Spiroplasma floricola cells. J Bacteriol 1992;174(13):4410-4415.

(65) Gallily R, Salman M, Tarshis M, Rottem S. Mycoplasma fermentans (incognitus strain) induces TNFα and IL-1 production by human monocytes and murine macrophages. Immunol Lett 1992;34(1):27-30.

(66) Rasmussen OF, Shirvan MH, Margalit H, Christiansen C, Rottem S. Nucleotide sequence, organization and characterization of the atp genes and the encoded subunits of Mycoplasma gallisepticum ATPase. Biochem J 1992;285(3):881-888.

(67) Tarshis M, Salman M, Rottem S. Fusion of mycoplasmas: the formation of cell hybrids. FEMS Microbiol Lett 1991;82(1):67-71.

(68) Salman M, Tarshis M, Rottem S. Small unilamellar vesicles are able to fuse with Mycoplasma capricolum cells. Biochim Biophys Acta Biomembr 1991;1063(2):209-216.

(69) Sher T, Yamin A, Rottem S, Gallily R. In vitro induction of tumor necrosis factor α, tumor cytolysis, and blast transformation by Spiroplasma membranes. J Natl Cancer Inst 1990;82(13):1142-1145.

(70) Renbaum P, Abrahamove D, Fainsod A, Wilson GG, Rottem S, Razin A. Cloning, characterization, and expression in Escherichia coli of the gene coding for the CpG DNA methylase from Spiroplasma sp. strain MQ1(M Sssl). Nucleic Acids Res 1990;18(5):1145-1152.

(71) Sher T, Rottem S, Gallily R. Mycoplasma capricolum membranes induce tumor necrosis factor α by a mechanism different from that of lipopolysaccharide. Cancer Immunol Immunother 1990;31(2):86-92.

(72) Platt MW, Reizer J, Rottem S. A 57-kilodalton protein associated with Spiroplasma melliferum fibrils undergoes reversible phosphorylation. J Bacteriol 1990;172(5):2808-2811.

(73) Sher T, Yamin A, Matzliach M, Rottem S, Gallily R. Partial biochemical characterization of spiroplasma membrane component inducing tumor necrosis factor alpha. Anticancer Drugs 1990;1(1):83-87.

(74) Rottem S, Groover K, Habig WH, Barile MF, Hardegree MC. Transmembrane diffusion channels in Mycoplasma gallisepticum induced by tetanolysin. Infect Immun 1990;58(3):598-602.

(75) Lelong I, Shirvan MH, Rottem S. A cation/proton antiport activity in Acholeplasma laidlawii. FEMS Microbiol Lett 1989;59(1-2):71-76.

(76) Shirvan MH, Schuldiner S, Rottem S. Volume regulation in Mycoplasma gallisepticum: Evidence that Na+ is extruded via a primary Na+ pump. J Bacteriol 1989;171(8):4417-4424.

(77) Shirvan MH, Schuldiner S, Rottem S. Role of Na+ cycle in cell volume regulation of Mycoplasma gallisepticum. J Bacteriol 1989;171(8):4410-4416.

(78) Chandler DKF, Olson LD, Kenimer JG, Probst PG, Rottem S, Grabowski MW, et al. Biological activities of monoclonal antibodies to Mycoplasma pneumoniae membrane glycolipids. Infect Immun 1989;57(4):1131-1136.

(79) Platt MW, Rottem S. Phosvitin kinase activity in Acholeplasma axanthum. FEBS Lett 1988;242(1):97-100.

(80) Lelong I, Luu B, Mersel M, Rottem S. Effect of 7β-hydroxycholesterol on growth and membrane composition of Mycoplasma capricolum. FEBS Lett 1988;232(2):354-358.

(81) Pakala R, Laskov R, Rottem S, Bachrach U. Effect of mycoplasma on polyamine synthesis and levels in NIH 3T3 cells and in cells transformed by Rous sarcoma virus. FEMS Microbiol Lett 1988;49(3):357-361.

(82) Fischer M, Shirvan MH, Platt MW, Kirchhoff H, Rottem S. Characterization of membrane components of the flask-shaped mycoplasma Mycoplasma mobile. J Gen Microbiol 1988;134(8):2385-2392.

(83) Citovsky V, Rottem S, Nussbaum O, Laster Y, Rott R, Loyter A. Animal viruses are able to fuse with prokaryotic cells. Fusion between Sendai or influenza virions and Mycoplasma. J Biol Chem 1988;263(1):461-467.

(84) PLATT MW, ROTTEM S, MILNER Y, BARILE MF, PETERKOFSKY A, RE1ZER J. Protein phosphorylation in Mycoplasma gallisepticum. Eur J Biochem 1988;176(1):61-67.

(85) Cirillo VP, Katzenell A, Rottem S. Sealed vesicles prepared by fusing Mycoplasma gallisepticum membranes and preformed lipid vesicles. Isr J Med Sci 1987;23(5):380-383.

(86) Shirvan MH, Schuldiner S, Rottem S. Control of sodium fluxes in Mycoplasma gallisepticum. Isr J Med Sci 1987;23(5):384-388.

(87) Rosen G, Frankenburg S, Rottem S, Londner MV. Characterization of lipidous antigens derived from erythrocytes infected with Plasmodium berghei. Isr J Med Sci 1987;23(8):873-876.

(88) Rottem S, Shirvan MH, Barile MF, Zilberstein D. Immunochemical evidence for an active (F1-F0)-ATPase in mycoplasmas. Isr J Med Sci 1987;23(5):389-392.

(89) Hackett KJ, Ginsberg AS, Rottem S, Henegar RB, Whitcomb RF. A defined medium for a fastidious spiroplasma. Science 1987;237(4814):525-527.

(90) Hackett KJ, Lynn DE, Ginsberg AS, Rottem S, Henegar RB, Adams J, et al. Cell-assisted culture of fastidious spiroplasmas: initial analysis of growth factors. Isr J Med Sci 1987;23(6):667-670.

(91) Egan W, Barile M, Rottem S. 31P-NMR studies of Mycoplasma gallisepticum cells using a continuous perfusion technique. FEBS Lett 1986;204(2):373-376.

(92) Rottem S, Cirillo VP. Transport in mycoplasmas. Methods Enzymol 1986;125(C):259-264.

(93) Gross Z, Rottem S. Lipid interconversions in aging Mycoplasma capricolum cultures. J Bacteriol 1986;167(3):986-991.

(94) Romano N, Shirvan MH, Rottem S. Changes in membrane lipid composition of Mycoplasma capricolum affect the cell volume. J Bacteriol 1986;167(3):1089-1091.

(95) Efrati H, Wax Y, Rottem S. Cholesterol uptake capacity of Acholeplasma laidlawii is affected by the composition and content of membrane glycolipids. Arch Biochem Biophys 1986;248(1):282-288.

(96) Zilberstein D, Shirvan MH, Barile MF, Rottem S. The β-subunit of the F1F0-ATPase is conserved in mycoplasmas. J Biol Chem 1986;261(16):7109-7111.

(97) Rottem S, Adar L, Gross Z, Ne'eman Z, Davis PJ. Incorporation and modification of exogenous phosphatidylcholines by mycoplasmas. J Bacteriol 1986;167(1):299-304.

(98) Nur I, Bove JM, Saillard C, Rottem S, Whitcomb RM, Razin S. DNA probes in detection of spiroplasmas and mycoplasma-like organisms in plants and insects. FEMS Microbiol Lett 1986;35(2-3):157-162.

(99) Nur I, Szyf M, Razin A, Glaser G, Rottem S. Procaryotic and eucaryotic traits of DNA methylation in spiroplasmas (Mycoplasmas). J Bacteriol 1985;164(1):19-24.

(100) Davis PJ, Katznel A, Razin S, Rottem S. Spiroplasma membrane lipids. J Bacteriol 1985;161(1):118-122.

(101) Gross Z, Rottem S. The preservation of Mycoplasma capricolum cell intactness after phospholipase A2 treatment. Biochim Biophys Acta Biomembr 1984;778(2):372-378.

(102) Hastings Wilson T, Linker C, Rottem S. Volume regulation in Mycoplasma gallisepticum. Isr J Med Sci 1984;20(9):800-802.

(103) Rottem S, Davis PJ, Gross Z, Ne'eman Z. Uptake and transbilayer distribution of phosphatidylcholines in Mycoplasma gallisepticum and their effect on cell morphology. Isr J Med Sci 1984;20(9):812-816.

(104) Honigman A, Kronman C, Nur I, Greenberg N, Rottem S. Cloning of L-2 DNA in Escherichia coli pOL4 plasmid. Isr J Med Sci 1984;20(9):793-796.

(105) Nur I, Razin S, Rottem S. Bilirubin incorporation into spiroplasma membranes and methylation of spiroplasmal DNA. Isr J Med Sci 1984;20(10):1019-1021.

(106) Rottem S, Yagen B, Katznell A. Effect of trichothecenes on growth and intracellular pool size of Mycoplasma gallisepticum. FEBS Lett 1984;175(1):189-192.

(107) Davis PJ, Efrati H, Raxin S, Rottem S. Two cholesterol pools in Acholeplasma laidlawii membranes. FEBS Lett 1984;175(1):51-54.

(108) Rottem S, Greenberg N. Binding of MVL-2 virus a A. Laidlawii cells. Yale J Biol Med 1983;56(5-6):765-769.

(109) Rottem S, Shirvan MH, Gross Z. Phase separation, ion permeability, and the isolation of membranes from osmotically stable mycoplasmas. Yale J Biol Med 1983;56(5-6):405-411.

(110) Bittman R, Clejan S, Rottem S. Transbilayer distribution of sterols in mycoplasma membranes. Yale J Biol Med 1983;56(5-6):397-403.

(111) Loewenstein J, Rottem S, Gallily R. Induction of macrophage-mediated cytolysis of neoplastic cells by mycoplasmas. Cell Immunol 1983;77(2):290-297.

(112) Gatt S, Morag B, Rottem S. Lysophospholipase-catalyzed hydrolysis of lysophospholipids in Mycoplasma gallisepticum membranes. J Bacteriol 1982;151(3):1095-1101.

(113) Rottem S, Cole RM, Habig WH, Barile MF, Hardegree MC. Structural characteristics of tetanolysin and its binding to lipid vesicles. J Bacteriol 1982;152(2):888-892.

(114) Nicolau C, Rottem S. Expression of A β-lactamase activity in Mycoplasma capricolum transfected with the liposome-encapsulated E. coli pBR 322 plasmid. Biochem Biophys Res Commun 1982;108(3):982-986.

(115) Rottem S. Properties of mycoplasmal membranes: summary. Rev Infect Dis 1982;4:S97-S98.

(116) Rottem S. Transbilayer Distribution of Lipids in Microbial Membranes. Curr Top Membr Transp 1982;17(C):235-261.

(117) Razin S, Rottem S. Preface. Curr Top Membr Transp 1982;17(C):17.

(118) Rottem S, Greenberg N. Molecular organization and selective solubilization of lipids and proteins in the envelope of mycoplasmal virus l2. Rev Infect Dis 1982;4:S99-S104.

(119) Melchior DL, Rottem S. Physical state of membrane lipids of mycoplasma capricolum. Rev Infect Dis 1982;4:S35-S42.

(120) Rottem S, Verkleij AJ. Possible association of segregated lipid domains of Mycoplasma gallisepticum membranes with cell resistance to osmotic lysis. J Bacteriol 1982;149(1):338-345.

(121) MARKOWITZ O, GROSS Z, ROTTEM S. The Effect of Phospholipase A2. on Intact Cells and Isolated Membranes of Mycoplasma gallisepticum. Eur J Biochem 1982;129(1):185-189.

(122) GROSS Z, ROTTEM S, BITTMAN R. Phospholipid Interconversions in Mycoplasma capriculum. Eur J Biochem 1982;122(1):169-174.

(123) Rosenberg M, Rottem S, Rosenberg E. Cell surface hydrophobicity of smooth and rough Proteus mirabilis strains as determined by adherence to hydrocarbons. FEMS Microbiol Lett 1982;13(2):167-169.

(124) Shirvan MH, Gross Z, Ne'eman Z, Rottem S. Isolation of Mycoplasma gallisepticum membranes by a mild alkaline-induced lysis of nonenergized cells. Curr Microbiol 1982;7(6):367-370.

(125) Razin S, Efrati H, Kutner S, Rottem S. Cholesterol and phospholipid uptake by mycoplasmas. Rev Infect Dis 1982;4:S85-S92.

(126) Shirvan MH, Rottem S, Neeman Z, Bittman R. Isolation of mycoplasma membranes by dicyclohexylcarbodiimide-induced lysis. J Bacteriol 1982;149(3):1124-1128.

(127) Strehler BL, Abraham S, Bayreuther K, Bienenstock A, Binstock R, Birren J, et al. Hayflick-NIH settlement [3]. Science 1982;215(4530):240-242.

(128) Rottem S, Shinar D, Bittman R. Symmetrical distribution and rapid transbilayer movement of cholesterol in Mycoplasma gallisepticum membranes. Biochim Biophys Acta Biomembr 1981;649(3):572-580.

(129) Rottem S. Cholesterol is required to prevent crystallization of Mycoplasma arginini phospholipids at physiological temperature. FEBS Lett 1981;133(1):161-164.

(130) Efrati H, Rottem S, Razin S. Lipid and protein membrane components associated with cholesterol uptake by mycoplasmas. Biochim Biophys Acta Biomembr 1981;641(2):386-394.

(131) MELCHIOR DL, ROTTEM S. The Organization of Cholesterol Esters in Membranes of Mycoplasma capricolum. Eur J Biochem 1981;117(1):147-153.

(132) Rottem S, Marcus M. Eliminating mycoplasmas from contaminated cell cultures. Isr J Med Sci 1981;17(7):569-571.

(133) Clejan S, Bittman R, Rottem S. Effects of Sterol Structure and Exogenous Lipids on the Transbilayer Distribution of Sterols in the Membrane of Mycoplasma capricolum. Biochemistry 1981;20(8):2200-2204.

(134) Rottem S, Linker C, Wilson TH. Proton motive force across the membrane of Mycoplasma gallisepticum and its possible role in cell volume regulation. J Bacteriol 1981;145(3):1299-1304.

(135) Bittman R, Blau L, Clejan S, Rottem S. Determination of Cholesterol Asymmetry by Rapid Kinetics of Filipin-Cholesterol Association: Effect of Modification in Lipids and Proteins. Biochemistry 1981;20(9):2425-2432.

(136) Marcus M, Lavi U, Nattenberg A, Rottem S, Markowitz O. Selective killing of mycoplasmas from contaminated mammalian cells in cell cultures. Nature 1980;285(5767):659-661.

(137) Bauminger ER, Cohen SG, Labenski De Kanter F, Levy A, Ofer S, Kessel M, et al. Iron storage in Mycoplasma capricolum. J Bacteriol 1980;141(1):378-381.

(138) Razin S, Kutner S, Efrati H, Rottem S. Phospholipid and cholesterol uptake by mycoplasma cells and membranes. Biochim Biophys Acta Biomembr 1980;598(3):628-640.

(139) Rottem S. Membrane lipids of mycoplasmas. Biochim Biophys Acta Biomembr 1980;604(1):65-90.

(140) Fishman Y, Rottem S, Citri N. Preferential suppression of normal exoenzyme formation by membrane-modifying agents. J Bacteriol 1980;141(3):1435-1438.

(141) Amar A, Kahane I, Rottem S, Razin S. Binding of lectins to membranes of mycoplasmas from aging cultures. Microbios 1979;24(96):93-102.

(142) Rottem S, Markowitz O. Unusual positional distribution of fatty acids in phosphatidylglycerol of sterol-requiring mycoplasmas. FEBS Lett 1979;107(2):379-382.

(143) Gross Z, Rottem S. Lipid distribution in Acholeplasma laidlawii membrane. A study using the lactoperoxidase-mediated iodination. Biochim Biophys Acta Biomembr 1979;555(3):547-552.

(144) Amar A, Rottem S, Razin S. Is the vertical disposition of mycoplasma membrane proteins affected by membrane fluidity? Biochim Biophys Acta Biomembr 1979;552(3):457-467.

(145) Rottem S, Markowitz O. Carotenoids act as reinforcers of the Acholeplasma laidlawii lipid bilayer. J Bacteriol 1979;140(3):944-948.

(146) DICKSON DPE, ROTTEM S. Mössbauer Spectroscopic Studies of Iron in Proteus mirabilis. Eur J Biochem 1979;101(1):291-295.

(147) Greenberg N, Rottem S. Composition and molecular organization of lipids and proteins in the envelope of mycoplasmavirus MVL2. J Virol 1979;32(3):717-726.

(148) Rottem S, Markowitz O. Membrane Lipids of Mycoplasma gallisepticum: A Disaturated Phosphatidylcholine and a Phosphatidylglycerol with an Unusual Positional Distribution of Fatty Acids. Biochemistry 1979;18(14):2930-2935.

(149) ROTTEM S, MARKOWITZ O, HASIN M, RAZIN S. Outer Membrane Proteins of Smooth and Rough Strains of Proteus mirabilis. Eur J Biochem 1979;97(1):141-146.

(150) Rottem S, Ulitzur S, Hasin M, Razin S. Susceptibility of phospholipids of Proteus mirabilis smooth and rough strains to endogenic phospholipase A activity. FEMS Microbiol Lett 1979;5(1):13-16.

(151) Bauminger ER, Cohen SG, Labenski de Kanter F, Levy A, Ofer S, Rottem S. EVIDENCE FOR THE OCCURRENCE OF A UNIVERSAL TYPE OF IRON STORAGE IN PROKARYOTIC CELLS: BACTERIA AND MYCOPLASMA. J Phys (Paris) Colloq 1979;41 Colloq C-1(1):491-492.

(152) Fishman Y, Rottem S, Citri N. Evidence linking penicillinase formation and secretion to lipid metabolism in Bacillus licheniformis. J Bacteriol 1978;134(2):434-439.

(153) Rottem S. The effect of lipid a on the fluidity and permeability propertes of phospholipid dispersions. FEBS Lett 1978;95(1):121-124.

(154) Nixdorff k, Martin HH, Rottem S, Razin S. EPR studies on model membranes of phospholipid and outer membrane proteins of Proteus mirabilis. FEBS Lett 1978;94(2):298-300.

(155) Amar A, Rottem S, Razin S. Disposition of membrane proteins as affected by changes in the electrochemical gradient across mycoplasma membranes. Biochem Biophys Res Commun 1978;84(2):306-312.

(156) Ofek I, Rottem S. Adherence of Proteus mirabilis S and R strains to human epithelial cells. FEMS Microbiol Lett 1978;4(4):229-232.

(157) Razin S, Rottem S. Cholesterol in membranes: Studies with mycoplasmas. Trends Biochem Sci 1978;3(1):51-55.

(158) Clejan S, Bittman R, Rottem S. Uptake, Transbilayer Distribution, and Movement of Cholesterol in Growing Mycoplasma capricolum Cells. Biochemistry 1978;17(22):4579-4583.

(159) ROTTEM S, MARKOWITZ O, RAZIN S. Thermal Regulation of the Fatty Acid Composition of Lipopolysaccharides and Phospholipids of Proteus mirabilis. Eur J Biochem 1978;85(2):445-450.

(160) ROTTEM S, MARKOWITZ O, RAZIN S. Cerulenin‐Induced Changes in the Lipopolysaccharide Content and Phospholipid Composition of Proteus mirabilis. Eur J Biochem 1978;85(2):451-456.

(161) Rottem S, Slutzky GM, Bittman R. Cholesterol Distribution and Movement in the Mycoplasma gallisepticum Cell Membrane. Biochemistry 1978;17(14):2723-2726.

(162) Clark MF, Flegg CL, Bar‐Joseph M, Rottem S. The Detection of Spiroplasma citri by Enzyme‐linked Immunosorbent Assay (ELISA). J Phytopathol 1978;92(4):332-337.

(163) Rottem S, Leive L. Effect of variations in lipopolysaccharide on the fluidity of the outer membrane of Escherichia coli. J Biol Chem 1977;252(6):2077-2081.

(164) Fishman Y, Citri N, Rottem S. Formation of penicillinase in cultures of Bacillus licheniformis treated with cerulenin. Isr J Med Sci 1977;13(9):958.

(165) Rottem S, Trotter SL, Barile MF. Membrane bound thioesterase activity in mycoplasmas. J Bacteriol 1977;129(2):707-713.

(166) Rottem S, Hardegree MC, Grabowski MW, Fornwald R, Barile MF. Interaction between tetanolysin and mycoplasma cell membrane. Biochim Biophys Acta Biomembr 1976;455(3):876-888.

(167) Grabowski MW, Rottem S, Barile MF. Cholesterol requirement of mycoplasmas as determined by a microtiter test using polyene antibiotics. J Clin Microbiol 1976;3(2):110-112.

(168) Bittman R, Rottem S. Distribution of cholesterol between the outer and inner halves of the lipid bilayer of mycoplasma cell membranes. Biochem Biophys Res Commun 1976;71(1):318-324.

(169) Hasin M, Razin S, Rottem S. The outer membrane of Proteus mirabilis III. Specific labeling and enzymic hydrolysis of the protein and phospholipid components of the outer and cytoplasmic membranes. Biochim Biophys Acta Biomembr 1976;433(2):229-239.

(170) Razin S, Marknowitz O, Hasin M, Rottem S. The outer membrane of Proteus mirabilis IV. Solubilization and fractionation of the outer and cytoplasmic membrane components. Biochim Biophys Acta Biomembr 1976;433(2):240-251.

(171) Schroit AJ, Rottem S, Gallily R. Motion of spin-labeled fatty acids in murine macrophages relation to cellular phagocytic activity. Biochim Biophys Acta Biomembr 1976;426(3):499-512.

(172) Amar A, Rottem S, Kahane I, Razin S. Characterization of the mycoplasma membrane proteins. VI. Composition and disposition of proteins in membranes from aging Mycoplasma hominis cultures. Biochim Biophys Acta Biomembr 1976;426(2):258-270.

(173) Rottem S, Barile MF. Effect of cerulenin on growth and lipid metabolism of mycoplasmas. Antimicrob Agents Chemother 1976;9(2):301-307.

(174) Romano N, Rottem S, Razin S. Biosynthesis of saturated and unsaturated fatty acids by a T strain mycoplasma (Ureaplasma). J Bacteriol 1976;128(1):170-173.

(175) Amar A, Rottem S, Kahane I, Razin S. Proceedings: Effects of the culture age on the composition and properties of Mycoplasma membranes. Isr J Med Sci 1975;11(11):1194.

(176) Rottem S. Heterogeneity in the physical state of the exterior and interior regions of mycoplasma membrane lipids. Biochem Biophys Res Commun 1975;64(1):7-12.

(177) Rottem S, Hasin M, Razin S. The outer membrane of Proteus mirabilis II. The extractable lipid fraction and electron-paramagnetic resonance analysis of the outer and cytoplasmic membranes. Biochim Biophys Acta Biomembr 1975;375(3):395-405.

(178) Hasin M, Rottem S, Razin S. The outer membrane of Proteus mirabilis I. Isolation and characterization of the outer and cytoplasmic membrane fractions. Biochim Biophys Acta Biomembr 1975;375(3):381-394.

(179) Rottem S, Greenberg AS. Changes in composition, biosynthesis, and physical state of membrane lipids occurring upon aging of Mycoplasma hominis cultures. J Bacteriol 1975;121(2):631-639.

(180) Raccach M, Rottem S, Razin S. Survival of frozen mycoplasmas. Appl Microbiol 1975;30(2):167-171.

(181) Amar A, Rottem S, Razin S. Characterization of the mycoplasma membrane proteins IV. Disposition of proteins in the membrane. Biochim Biophys Acta Biomembr 1974;352(2):228-244.

(182) Razin S, Rottem S. [42] Isolation, Solubilization, and Reconstitution of Mycoplasma Membranes. Methods Enzymol 1974;32(C):459-468.

(183) Razin S, Hasin M, Ne'eman Z, Rottem S. Isolation, chemical composition, and ultrastructural features of the cell membrane of the mycoplasma like organism Spiroplasma citri. J Bacteriol 1973;116(3):1421-1435.

(184) Rottem S, Hasin M, Razin S. Differences in susceptibility to phospholipase C of free and membrane-bound phospholipids of Mycoplasma hominis. Biochim Biophys Acta Biomembr 1973;323(4):520-531.

(185) Rottem S, Yashouv J, Ne'eman Z, Razin S. Cholesterol in mycoplasma membranes. Composition, ultrastructure and biological properties of membranes from Mycoplasma mycoides var. capri cells adapted to grow with low cholesterol concentrations. Biochim Biophys Acta Biomembr 1973;323(4):495-508.

(186) Rottem S, Cirillo VP, De Kruyff B, Shinitzky M, Razin S. Cholesterol in mycoplasm membranes. Correlation of enzymic and transport activities with physical state of lipids in membranes of Mycoplasma mycoides var. capri adapted to grow with low cholesterol concentrations. Biochim Biophys Acta Biomembr 1973;323(4):509-519.

(187) Rottem S, Hasin M, Razin S. Binding of proteins to mycoplasma membranes. Biochim Biophys Acta Biomembr 1973;298(4):876-886.

(188) Rottem S, Samuni A. Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma membranes. Biochim Biophys Acta Biomembr 1973;298(1):32-38.

(189) Rottem S, Razin S. Membrane lipids of Mycoplasma hominis. J Bacteriol 1973;113(2):565-571.

(190) Rottem S, Muhsam-Peled O, Razin S. Acyl carrier protein in mycoplasmas. J Bacteriol 1973;113(2):586-591.

(191) Rottem S, Hayflick L. Circular dichroism analysis of native and reaggregated mycoplasma membranes. Can J Biochem 1973;51(5):632-636.

(192) Razin S, Rottem S, Hasin M, Gershfeld NL. BINDING OF EXOGENOUS PROTEINS AND LIPIDS TO MYCOPLASMA MEMBRANES. Ann New York Acad Sci 1973;225(1):28-37.

(193) Rottem S, Razin S. Isolation of mycoplasma membranes by digitonin. J Bacteriol 1972;110(2):699-705.

(194) Bredt W, Maniloff J, Das J, Quinlan D, Biberfeld G, Biberfeld P, et al. International mycoplasma symposium 6/7th September 1971 in Mainz Summaries of the papers. Med Microbiol Immunol 1972;157(2):169-180.

(195) Rottem S. Differentiation of sterol-requiring from sterol-nonrequiring mycoplasmas by amphotericin B. Appl Microbiol 1972;23(3):659-660.

(196) Rottem S, Kalkstein A, Citri N. Incorporation of penicillinase into reaggregated mycoplasma membranes. Biochim Biophys Acta Biomembr 1971;241(2):593-599.

(197) Rottem S, Pfendt EA, Hayflick L. Sterol requirements of T-strain mycoplasmas. J Bacteriol 1971;105(1):323-330.

(198) Rottem S, Hubbell WL, Hayflick L, McConnell HM. Motion of fatty acid spin labels in the plasma membrane of mycoplasma. Biochim Biophys Acta Biomembr 1970;219(1):104-113.

(199) Panos C, Rottem S. Incorporation and Elongation of Fatty Acid Isomers by Mycoplasma Laidlawii A. Biochemistry 1970;9(2):407-412.

(200) Rottem S, Panos C. The Synthesis of Long-Chain Fatty Acids by a Cell-Free System from Mycoplasma laidlawii A. Biochemistry 1970;9(1):57-63.

(201) Rottem S, Panos C. The effect of long chain fatty acid isomers on growth, fatty acid composition and osmotic fragility of Mycoplasma laidlawii A. J Gen Microbiol 1969;59(3):317-328.

(202) Rottem S, Razin S. Sugar transport in Mycoplasma gallisepticum. J Bacteriol 1969;97(2):787-792.

(203) Razin S, Gottfried L, Rottem S. Amino acid transport in Mycoplasma. J Bacteriol 1968;95(5):1685-1691.

(204) Rottem S, Gottfried L, Razin S. Carotenoids as protectors against photodynamic inactivation of the adenosine triphosphatase of Mycoplasma laidlawii membranes. Biochem J 1968;109(4):707-708.

(205) Rottem S, Stein O, Razin S. Reassembly of Mycoplasma membranes disaggregated by detergents. Arch Biochem Biophys 1968;125(1):46-56.

(206) Razin S, Rottem S. Identification of Mycoplasma and other microorganisms by polyacrylamide-gel electrophoresis of cell proteins. J Bacteriol 1967;94(6):1807-1810.

(207) Rottem S, Razin S. Electrophoretic patterns of membrane proteins of Mycoplasma. J Bacteriol 1967;94(2):359-364.

(208) Razin S, Rottem S. Role of carotenoids and cholesterol in the growth of Mycoplasma laidlawii. J Bacteriol 1967;93(3):1181-1182.

(209) Rodwell AW, Razin S, Rottem S, Argaman M. Association of protein and lipid in Mycoplasma laidlawii membranes disaggregated by detergents. Arch Biochem Biophys 1967;122(3):621-628.

(210) Rottem S, Razin S. Adenosine triphosphatase activity of mycoplasma membranes. J Bacteriol 1966;92(3):714-722.

(211) ROTTEM S, RAZIN S. LIPASE ACTIVITY OF MYCOPLASMA. J Gen Microbiol 1964;37:123-134.