School of Pharmacy : Mechoulam Raphael

1.

Shahen-Zoabi S, Smoum R, Bingor A, Grad E, Nemirovski A, Shekh-Ahmad T, et al. N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice. Translational Psychiatry [Internet]. 2023;13(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85166047559&doi=10.1038%252fs41398-023-02574-4&partnerID=40&md5=cd89b17bb32b6271ad249c511e9f49c1

2.

Colodete DAE, Silva NR, Pedrazzi JFC, Fogaça MV, Cortez I, Del-Bel EA, et al. Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556. Behavioural Pharmacology [Internet]. 2023;34(4):213–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159739635&doi=10.1097%252fFBP.0000000000000727&partnerID=40&md5=e534e6fd4bbacf9965cb0f4aeac03bf5

3.

Lavi Y, Kogan NM, Topping LM, Liu C, McCann FE, Williams RO, et al. Novel Synthesis of C-Methylated Phytocannabinoids Bearing Anti-inflammatory Properties. Journal of Medicinal Chemistry [Internet]. 2023;66(8):5536–49. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85154041245&doi=10.1021%252facs.jmedchem.2c01988&partnerID=40&md5=2852710b1f1333a4404dc1f5a11dc00f

4.

Hen-Shoval D, Moshe L, Indig-Naimer T, Mechoulam R, Shoval G, Zalsman G, et al. Cannabinoid Receptor 2 Blockade Prevents Anti-Depressive-like Effect of Cannabidiol Acid Methyl Ester in Female WKY Rats. International Journal of Molecular Sciences [Internet]. 2023;24(4). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149030428&doi=10.3390%252fijms24043828&partnerID=40&md5=7aa4fb1e3e657c92b8bc7b955099623e

5.

Mechoulam R. A Delightful Trip Along the Pathway of Cannabinoid and Endocannabinoid Chemistry and Pharmacology. Annual Review of Pharmacology and Toxicology [Internet]. 2023;63:1–13. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147045307&doi=10.1146%252fannurev-pharmtox-051921-083709&partnerID=40&md5=bd8b094f2a555d2a6c5932bce4e37fe4

6.

Kogan NM, Begmatova D, Vinnikova L, Malitsky S, Itkin M, Sharon E, et al. Endocannabinoid basis of personality—Insights from animal model of social behavior. Frontiers in Pharmacology [Internet]. 2023;14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85169559608&doi=10.3389%252ffphar.2023.1234332&partnerID=40&md5=2e14d15a733aecdede5c046bb694cdfe

7.

Linher-Melville K, Mechoulam R, Singh G. Cannabidiolic acid (CBDA), features and profiles: Anti-hyperalgesic effects [Internet]. Medicinal Usage of Cannabis and Cannabinoids. 2023. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85166033201&doi=10.1016%252fB978-0-323-90036-2.00005-3&partnerID=40&md5=da17953d258541bf419df7c2b83a4381

8.

Carmon I, Zecharyahu L, Elayyan J, Meka SRK, Reich E, Kandel L, et al. HU308 Mitigates Osteoarthritis by Stimulating Sox9-Related Networks of Carbohydrate Metabolism. Journal of Bone and Mineral Research [Internet]. 2023;38(1):154–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85142856283&doi=10.1002%252fjbmr.4741&partnerID=40&md5=f1e2041c20a14024572e8e8142b82467

9.

Carmon I, Smoum R, Farhat E, Reich E, Kandel L, Yekhtin Z, et al. A Fenchone Derivative Effectively Abrogates Joint Damage Following Post-Traumatic Osteoarthritis in Lewis Rats. Cells [Internet]. 2022;11(24). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144565505&doi=10.3390%252fcells11244084&partnerID=40&md5=495c08f4849f525f527b06c27b197cda

10.

Souza JDS, Zuardi AW, Guimarães FS, Osório FDL, Loureiro SR, Campos AC, et al. Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic. Frontiers in Pharmacology [Internet]. 2022;13. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140039774&doi=10.3389%252ffphar.2022.856846&partnerID=40&md5=1c6e90ec34405f90c621d8e7bea9a245

11.

Crippa JAS, Pacheco JC, Zuardi AW, Guimarães FS, Campos AC, Osório FDL, et al. Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Cannabis and Cannabinoid Research [Internet]. 2022;7(5):658–69. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141604677&doi=10.1089%252fcan.2021.0093&partnerID=40&md5=cdda50992ecf9f16b5b2b77a0e9a7897

12.

Cortez IL, Silva NR, Rodrigues NS, Pedrazzi JFC, Del Bel EA, Mechoulam R, et al. HU-910, a CB2 receptor agonist, reverses behavioral changes in pharmacological rodent models for schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry [Internet]. 2022;117. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127472688&doi=10.1016%252fj.pnpbp.2022.110553&partnerID=40&md5=6d2ceef41d50eb1f8b6fd23f89d567b4

13.

Sionov RV, Banerjee S, Bogomolov S, Smoum R, Mechoulam R, Steinberg D. Targeting the Achilles’ Heel of Multidrug-Resistant Staphylococcus aureus by the Endocannabinoid Anandamide. International Journal of Molecular Sciences [Internet]. 2022;23(14). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85135099855&doi=10.3390%252fijms23147798&partnerID=40&md5=a3140553412957d3937806920dc030be

14.

Golan H, Mechoulam R, Smoum R, Cohen-Zada E, Pri-Chen S, Wiener S, et al. Anti-Tumorigenic Effect of a Novel Derivative of 2-Hydroxyoleic Acid and the Endocannabinoid Anandamide on Neuroblastoma Cells. Biomedicines [Internet]. 2022;10(7). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133606990&doi=10.3390%252fbiomedicines10071552&partnerID=40&md5=c81cf08459f0d545369f014f935fd4e0

15.

Bar-Lev Schleider L, Mechoulam R, Sikorin I, Naftali T, Novack V. Adherence, Safety, and Effectiveness of Medical Cannabis and Epidemiological Characteristics of the Patient Population: A Prospective Study. Frontiers in Medicine [Internet]. 2022;9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125253874&doi=10.3389%252ffmed.2022.827849&partnerID=40&md5=fb4e336313960bfc0e1732e026f03111

16.

Smoum R, Haj C, Hirsch S, Nemirovski A, Yekhtin Z, Bogoslavsky B, et al. Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential. Molecules [Internet]. 2022;27(4). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125198335&doi=10.3390%252fmolecules27041382&partnerID=40&md5=5e351bc05325348ae5ef41ac41d25069

17.

Rock EM, Limebeer CL, Smoum R, Mechoulam R, Parker LA. Effect of oleoyl glycine and oleoyl alanine on lithium chloride induced nausea in rats and vomiting in shrews. Psychopharmacology [Internet]. 2022;239(2):377–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117471784&doi=10.1007%252fs00213-021-06005-4&partnerID=40&md5=6a80a91052bc15f4ee5e5892423092c6

18.

Silva NR, Gomes FIF, Lopes AHP, Cortez IL, dos Santos JC, Silva CEA, et al. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics [Internet]. 2022;19(1):434–49. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121135246&doi=10.1007%252fs13311-021-01164-w&partnerID=40&md5=e632373f65e7235c83194ff034c6564c

19.

Murillo-Rodríguez E, Millán-Aldaco D, Arankowsky-Sandoval G, Yamamoto T, Pertwee RG, Parker L, et al. Assessing the treatment of cannabidiolic acid methyl ester: a stable synthetic analogue of cannabidiolic acid on c-Fos and NeuN expression in the hypothalamus of rats. Journal of Cannabis Research [Internet]. 2021;3(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147136768&doi=10.1186%252fs42238-021-00081-1&partnerID=40&md5=6d3cd4975e9929025c5cefcbc1194812

20.

Banerjee S, Sionov RV, Feldman M, Smoum R, Mechoulam R, Steinberg D. Anandamide alters the membrane properties, halts the cell division and prevents drug efflux in multidrug resistant Staphylococcus aureus. Scientific Reports [Internet]. 2021;11(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104662667&doi=10.1038%252fs41598-021-88099-6&partnerID=40&md5=80946108a375670d3d54a78d51557dfe

21.

Ayoub SM, Piscitelli F, Silvestri C, Limebeer CL, Rock EM, Smoum R, et al. Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators. Frontiers in Pharmacology [Internet]. 2021;12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116030959&doi=10.3389%252ffphar.2021.706703&partnerID=40&md5=fc6e1bd2b4991714142363fbb865d6d1

22.

Crippa JAS, Zuardi AW, Guimarães FS, Campos AC, De Lima Osório F, Loureiro SR, et al. Efficacy and Safety of Cannabidiol plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout among Frontline Health Care Workers during the COVID-19 Pandemic: A Randomized Clinical Trial. JAMA Network Open [Internet]. 2021;4(8). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113161591&doi=10.1001%252fjamanetworkopen.2021.20603&partnerID=40&md5=ee83c238d7c4f5a07b8dab28e3ad83b1

23.

Rock EM, Limebeer CL, Pertwee RG, Mechoulam R, Parker LA. Therapeutic Potential of Cannabidiol, Cannabidiolic Acid, and Cannabidiolic Acid Methyl Ester as Treatments for Nausea and Vomiting. Cannabis and Cannabinoid Research [Internet]. 2021;6(4):266–74. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112325925&doi=10.1089%252fcan.2021.0041&partnerID=40&md5=2059c753f88a868e9b3f9358f7f31091

24.

Rock EM, Limebeer CL, Sullivan MT, DeVuono MV, Lichtman AH, Di Marzo V, et al. N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine. Frontiers in Synaptic Neuroscience [Internet]. 2021;13. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102945086&doi=10.3389%252ffnsyn.2021.620145&partnerID=40&md5=f7371babd1bdb9dc7ac77cc5eb6e6fbd

25.

Kogan NM, Peters M, Mechoulam R. Cannabinoid quinones—a review and novel observations. Molecules [Internet]. 2021;26(6). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103862464&doi=10.3390%252fmolecules26061761&partnerID=40&md5=a6d3145a4f8c101abb2f4a9dd95b1f29

26.

Feldman M, Sionov RV, Mechoulam R, Steinberg D. Anti-biofilm activity of cannabidiol against candida albicans. Microorganisms [Internet]. 2021;9(2):1–17. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100928444&doi=10.3390%252fmicroorganisms9020441&partnerID=40&md5=5fc397041c72e371cff73961fb5d41d8

27.

Di Bartolomeo M, Stark T, Maurel OM, Iannotti FA, Kuchar M, Ruda-Kucerova J, et al. Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats. Pharmacological Research [Internet]. 2021;164. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099693901&doi=10.1016%252fj.phrs.2020.105357&partnerID=40&md5=5dc344b78b84ddba30a8f6130fd752ad

28.

Mechoulam R. Foreword. Advances in Experimental Medicine and Biology [Internet]. 2021;1264:ix–xi. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097980294&partnerID=40&md5=0ccbf8ac0d8ccb3bb63d4545dc245dce

29.

Sionov RV, Feldman M, Smoum R, Mechoulam R, Steinberg D. Anandamide prevents the adhesion of filamentous Candida albicans to cervical epithelial cells. Scientific Reports [Internet]. 2020;10(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089363671&doi=10.1038%252fs41598-020-70650-6&partnerID=40&md5=7c9e43a9748c6ae6629f347a99443e62

30.

Ayoub SM, Smoum R, Farag M, Atwal H, Collins SA, Rock EM, et al. Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats. Psychopharmacology [Internet]. 2020;237(9):2753–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086590269&doi=10.1007%252fs00213-020-05570-4&partnerID=40&md5=1b55b5a41c56e2b931381a2b7d73c9ea

31.

Rock EM, Sullivan MT, Collins SA, Goodman H, Limebeer CL, Mechoulam R, et al. Evaluation of repeated or acute treatment with cannabidiol (CBD), cannabidiolic acid (CBDA) or CBDA methyl ester (HU-580) on nausea and/or vomiting in rats and shrews. Psychopharmacology [Internet]. 2020;237(9):2621–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085926873&doi=10.1007%252fs00213-020-05559-z&partnerID=40&md5=2b7cec001038971c0419f228c73dc2ce

32.

Stark T, Di Bartolomeo M, Di Marco R, Drazanova E, Platania CBM, Iannotti FA, et al. Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. Biochemical Pharmacology [Internet]. 2020;177. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085088230&doi=10.1016%252fj.bcp.2020.114004&partnerID=40&md5=aea355817395d1786720c114846e59ce

33.

Zhu YF, Linher-Melville K, Niazmand MJ, Sharma M, Shahid A, Zhu KL, et al. An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain. British Journal of Pharmacology [Internet]. 2020;177(12):2712–25. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081242816&doi=10.1111%252fbph.14997&partnerID=40&md5=c95c6bf9c35fa656a8446bd38bcf23f9

34.

Piscitelli F, Guida F, Luongo L, Iannotti FA, Boccella S, Verde R, et al. Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury. ACS Chemical Neuroscience [Internet]. 2020;11(8):1117–28. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083544901&doi=10.1021%252facschemneuro.9b00633&partnerID=40&md5=4f700593b9bf9a6e734ba2c2c918c7d7

35.

Murillo-Rodríguez E, Arankowsky-Sandoval G, Pertwee RG, Parker L, Mechoulam R. Sleep and neurochemical modulation by cannabidiolic acid methyl ester in rats. Brain Research Bulletin [Internet]. 2020;155:166–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076546426&doi=10.1016%252fj.brainresbull.2019.12.006&partnerID=40&md5=8f827269281da73b0fba157d25bc2d75

36.

Rock EM, Ayoub SM, Limebeer CL, Gene A, Wills KL, DeVuono MV, et al. Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine. Psychopharmacology [Internet]. 2020;237(2):375–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075116189&doi=10.1007%252fs00213-019-05373-2&partnerID=40&md5=19df02718bbe5bf48d846c79bd1855f3

37.

Pacher P, Kogan NM, Mechoulam R. Beyond THC and endocannabinoids. Annual Review of Pharmacology and Toxicology [Internet]. 2020;60:637–59. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077762106&doi=10.1146%252fannurev-pharmtox-010818-021441&partnerID=40&md5=b51caa875fe1231ff2bc769eafd27503

38.

Feldman M, Sionov R, Smoum R, Mechoulam R, Ginsburg I, Steinberg D. Comparative Evaluation of Combinatory Interaction between Endocannabinoid System Compounds and Poly-L-lysine against Streptococcus mutans Growth and Biofilm Formation. BioMed Research International [Internet]. 2020;2020. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079384956&doi=10.1155%252f2020%252f7258380&partnerID=40&md5=6633ccad493471e8ea50b5e2ef5cb2be

39.

Bar-Lev Schleider L, Mechoulam R, Saban N, Meiri G, Novack V. Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy. Scientific Reports [Internet]. 2019;9(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060152498&doi=10.1038%252fs41598-018-37570-y&partnerID=40&md5=5e10f028085ee7b04bc4a3bc11941bdb

40.

Baraghithy S, Smoum R, Attar-Namdar M, Mechoulam R, Bab I, Tam J. Hu-671, a novel oleoyl serine derivative, exhibits enhanced efficacy in reversing ovariectomy-induced osteoporosis and bone marrow adiposity. Molecules [Internet]. 2019;24(20). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073635290&doi=10.3390%252fmolecules24203719&partnerID=40&md5=111b4e8e5fa4e83e1a3c26e75eb55dc4

41.

Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, et al. Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats. Psychopharmacology [Internet]. 2019;236(9):2623–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064538470&doi=10.1007%252fs00213-019-05237-9&partnerID=40&md5=a1c942199e2a0a149aed4a83bd97f645

42.

Friedman L, Smoum R, Feldman M, Mechoulam R, Steinberg D. Does the Endocannabinoid Anandamide Affect Bacterial Quorum Sensing, Vitality, and Motility? Cannabis and Cannabinoid Research [Internet]. 2019;4(2):102–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067611419&doi=10.1089%252fcan.2018.0055&partnerID=40&md5=cec0eb3f820cc9edab9fe24bf0010d3d

43.

Magid L, Heymann S, Elgali M, Avram L, Cohen Y, Liraz-Zaltsman S, et al. Role of CB2 Receptor in the Recovery of Mice after Traumatic Brain Injury. Journal of Neurotrauma [Internet]. 2019;36(11):1836–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066734410&doi=10.1089%252fneu.2018.6063&partnerID=40&md5=8920fe80310af10271c28fba22009ca5

44.

Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D’Aniello E, et al. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology [Internet]. 2019;148:320–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054609363&doi=10.1016%252fj.neuropharm.2018.03.020&partnerID=40&md5=c35d103f5d5398473602cef25a84a75e

45.

Shbiro L, Hen-Shoval D, Hazut N, Rapps K, Dar S, Zalsman G, et al. Effects of cannabidiol in males and females in two different rat models of depression. Physiology and Behavior [Internet]. 2019;201:59–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058631072&doi=10.1016%252fj.physbeh.2018.12.019&partnerID=40&md5=daf65649f02e1ef2cd2af6f44a4df61b

46.

Stark T, Ruda-Kucerova J, Iannotti FA, D’Addario C, Di Marco R, Pekarik V, et al. Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. Neuropharmacology [Internet]. 2019;146:212–21. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058120018&doi=10.1016%252fj.neuropharm.2018.11.035&partnerID=40&md5=053a43ac683d74184d49576dee69df7c

47.

Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Morales-Lara D, Mechoulam R, Drucker-Colín R. Cannabidiol partially blocks the excessive sleepiness in hypocretin-deficient rats: Preliminary data. CNS and Neurological Disorders - Drug Targets [Internet]. 2019;18(9):705–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078547731&doi=10.2174%252f1871527318666191021143300&partnerID=40&md5=060f430f0edf4c585e19ec187417280e

48.

Linares IM, Zuardi AW, Pereira LC, Queiroz RH, Mechoulam R, Guimarães FS, et al. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Revista Brasileira de Psiquiatria [Internet]. 2019;41(1):9–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061284697&doi=10.1590%252f1516-4446-2017-0015&partnerID=40&md5=5d8c65b1fd8a0d1b9c276a054589fabc

49.

Baraghithy S, Smoum R, Drori A, Hadar R, Gammal A, Hirsch S, et al. Magel2 Modulates Bone Remodeling and Mass in Prader-Willi Syndrome by Affecting Oleoyl Serine Levels and Activity. Journal of Bone and Mineral Research [Internet]. 2019;34(1):93–105. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055261214&doi=10.1002%252fjbmr.3591&partnerID=40&md5=73b09e7acf74311a63ae1fd6a5d8fb6e

50.

Feldman M, Smoum R, Mechoulam R, Steinberg D. Antimicrobial potential of endocannabinoid and endocannabinoid-like compounds against methicillin-resistant Staphylococcus aureus. Scientific Reports [Internet]. 2018;8(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057979493&doi=10.1038%252fs41598-018-35793-7&partnerID=40&md5=1566eee5fb916da084cbc6d10f44aba1

51.

Chiurchiù V, Leuti A, Smoum R, Mechoulam R, Maccarrone M. Bioactive lipids ALIAmides differentially modulate inflammatory responses of distinct subsets of primary human T lymphocytes. FASEB Journal [Internet]. 2018;32(10):5716–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052874071&doi=10.1096%252ffj.201800107R&partnerID=40&md5=b8c371a158f09e98b9bd5e80b3be9bda

52.

Hen-Shoval D, Amar S, Shbiro L, Smoum R, Haj CG, Mechoulam R, et al. Acute oral cannabidiolic acid methyl ester reduces depression-like behavior in two genetic animal models of depression. Behavioural Brain Research [Internet]. 2018;351:1–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047846392&doi=10.1016%252fj.bbr.2018.05.027&partnerID=40&md5=fcbdd3c9fdddcd721dd43b72edf108f9

53.

Bar-Lev Schleider L, Mechoulam R, Lederman V, Hilou M, Lencovsky O, Betzalel O, et al. Prospective analysis of safety and efficacy of medical cannabis in large unselected population of patients with cancer. European Journal of Internal Medicine [Internet]. 2018;49:37–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042382685&doi=10.1016%252fj.ejim.2018.01.023&partnerID=40&md5=5de51d807305bc69098de93371ecd4a8

54.

Abuhasira R, Schleider LBL, Mechoulam R, Novack V. Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly. European Journal of Internal Medicine [Internet]. 2018;49:44–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041573337&doi=10.1016%252fj.ejim.2018.01.019&partnerID=40&md5=6b82e23b588878d481ca13da0b687a9e

55.

Pertwee RG, Rock EM, Guenther K, Limebeer CL, Stevenson LA, Haj C, et al. Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats. British Journal of Pharmacology [Internet]. 2018;175(1):100–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037366203&doi=10.1111%252fbph.14073&partnerID=40&md5=b4c68d1cb5339713921ac5fa7da5afef

56.

Večeřa J, Bártová E, Krejčí J, Legartová S, Komůrková D, Rudá-Kučerová J, et al. HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals. Journal of Cellular Physiology [Internet]. 2018;233(1):530–48. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018336186&doi=10.1002%252fjcp.25914&partnerID=40&md5=b35ca11a46e19b2f257bdb6194eec7d0

57.

Wang Y, Mukhopadhyay P, Cao Z, Wang H, Feng D, Haskó G, et al. Cannabidiol attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury. Scientific Reports [Internet]. 2017;7(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029859484&doi=10.1038%252fs41598-017-10924-8&partnerID=40&md5=eb3ae442f74b8c148279dd63038423d2

58.

Silva NR, Gomes FV, Fonseca MD, Mechoulam R, Breuer A, Cunha TM, et al. Antinociceptive effects of HUF-101, a fluorinated cannabidiol derivative. Progress in Neuro-Psychopharmacology and Biological Psychiatry [Internet]. 2017;79:369–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85024927418&doi=10.1016%252fj.pnpbp.2017.07.012&partnerID=40&md5=67abee532daa7784ccfc1517b5803eac

59.

Rock EM, Limebeer CL, Petrie GN, Williams LA, Mechoulam R, Parker LA. Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats. Psychopharmacology [Internet]. 2017;234(14):2207–17. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018461372&doi=10.1007%252fs00213-017-4626-5&partnerID=40&md5=bf2e43a14c240f2458e33a253885acef

60.

Mechoulam R. Foreword [Internet]. Cannabis sativa L. - Botany and Biotechnology. 2017. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033570799&doi=10.1007%252f978-3-319-54564-6&partnerID=40&md5=e523d4bbedfc212bd8119cae256f155e

61.

Mechoulam R. Cannabis and epilepsy. Epilepsy and Behavior [Internet]. 2017;70:278–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013127794&doi=10.1016%252fj.yebeh.2017.01.014&partnerID=40&md5=95358d9ab6466278c4ae09d4344771d3

62.

Rock EM, Boulet N, Limebeer CL, Mechoulam R, Parker LA. Cannabinoid 2 (CB2) receptor agonism reduces lithium chloride-induced vomiting in Suncus murinus and nausea-induced conditioned gaping in rats. European Journal of Pharmacology [Internet]. 2016;786:94–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973496628&doi=10.1016%252fj.ejphar.2016.06.001&partnerID=40&md5=794b29ae8f5f284174e7fc9210b74ea3

63.

Breuer A, Haj CG, Fogaça MV, Gomes FV, Silva NR, Pedrazzi JF, et al. Fluorinated cannabidiol derivatives: Enhancement of activity in mice models predictive of anxiolytic, antidepressant and antipsychotic effects. PLoS ONE [Internet]. 2016;11(7). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978636526&doi=10.1371%252fjournal.pone.0158779&partnerID=40&md5=c280ad1c2b06e00001c61023e24e162e

64.

Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z. Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - Studies in BV-2 microglia and encephalitogenic T cells. Journal of Basic and Clinical Physiology and Pharmacology [Internet]. 2016;27(3):289–96. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969796352&doi=10.1515%252fjbcpp-2015-0071&partnerID=40&md5=80807b0dd697f93b78426f1e0c520167

65.

Mann A, Cohen-Yeshurun A, Trembovler V, Mechoulam R, Shohami E. Are the endocannabinoid-like compounds N-acyl aminoacids neuroprotective after traumatic brain injury? Journal of Basic and Clinical Physiology and Pharmacology [Internet]. 2016;27(3):209–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969765402&doi=10.1515%252fjbcpp-2015-0092&partnerID=40&md5=fed739815443202015f72574d373944d

66.

Mechoulam R. Cannabis - The Israeli perspective. Journal of Basic and Clinical Physiology and Pharmacology [Internet]. 2016;27(3):181–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969751540&doi=10.1515%252fjbcpp-2015-0091&partnerID=40&md5=591de62592af3129ec1b8fc583906909

67.

Maslov LN, Khaliulin I, Zhang Y, Krylatov AV, Naryzhnaya NV, Mechoulam R, et al. Prospects for Creation of Cardioprotective Drugs Based on Cannabinoid Receptor Agonists. Journal of Cardiovascular Pharmacology and Therapeutics [Internet]. 2016;21(3):262–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84963657265&doi=10.1177%252f1074248415612593&partnerID=40&md5=63fbe3d766aba362211ad563b9de56d9

68.

Shoval G, Shbiro L, Hershkovitz L, Hazut N, Zalsman G, Mechoulam R, et al. Prohedonic effect of cannabidiol in a rat model of depression. Neuropsychobiology [Internet]. 2016;73(2):123–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969130031&doi=10.1159%252f000443890&partnerID=40&md5=e094588571e5f8b8677da32a33878c0b

69.

Lee WS, Erdelyi K, Matyas C, Mukhopadhyay P, Varga ZV, Liaudet L, et al. Cannabidiol limits T cell–mediated chronic autoimmune myocarditis: Implications to autoimmune disorders and organ transplantation. Molecular Medicine [Internet]. 2016;22:136–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84987630537&doi=10.2119%252fmolmed.2016.00007&partnerID=40&md5=fe938e17b18ba6008acce171d6082488

70.

Fisher T, Golan H, Schiby G, Prichen S, Smoum R, Moshe I, et al. In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma. Current Oncology [Internet]. 2016;23:S15–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84961647327&doi=10.3747%252fco.23.2893&partnerID=40&md5=d5f3ef30f5a2a4d526b431c800607ce8

71.

Kozela E, Haj C, Hanuš L, Chourasia M, Shurki A, Juknat A, et al. HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells. Chemical Biology and Drug Design [Internet]. 2016;87(1):143–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955680446&doi=10.1111%252fcbdd.12637&partnerID=40&md5=9977249d43d1b61a71d7ada87a82eaf1

72.

Kogan NM, Melamed E, Wasserman E, Raphael B, Breuer A, Stok KS, et al. Cannabidiol, a major non-psychotropic cannabis constituent enhances fracture healing and stimulates lysyl hydroxylase activity in osteoblasts. Journal of Bone and Mineral Research [Internet]. 2015;30(10):1905–13. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84942196009&doi=10.1002%252fjbmr.2513&partnerID=40&md5=59e016adac97153283ffbaa76bb3b8ea

73.

Haj CG, Sumariwalla PF, Hanuš L, Kogan NM, Yektin Z, Mechoulam R, et al. HU-444, a novel, potent anti-inflammatory, nonpsychotropic cannabinoid. Journal of Pharmacology and Experimental Therapeutics [Internet]. 2015;355(1):66–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941695739&doi=10.1124%252fjpet.115.226100&partnerID=40&md5=9a925241d30d963be06ad50c77cdfcdf

74.

Yeshurun M, Shpilberg O, Herscovici C, Shargian L, Dreyer J, Peck A, et al. Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study. Biology of Blood and Marrow Transplantation [Internet]. 2015;21(10):1770–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941315324&doi=10.1016%252fj.bbmt.2015.05.018&partnerID=40&md5=befa8da830da855e667483ac2ac04e70

75.

Soni D, Smoum R, Breuer A, Mechoulam R, Steinberg D. Effect of the synthetic cannabinoid HU-210 on quorum sensing and on the production of quorum sensing-mediated virulence factors by Vibrio harveyi. BMC Microbiology [Internet]. 2015;15(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938918291&doi=10.1186%252fs12866-015-0499-0&partnerID=40&md5=6191014017dcc88e3088ab33136c64a3

76.

Smoum R, Baraghithy S, Chourasia M, Breuer A, Mussai N, Attar-Namdar M, et al. CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2015;112(28):8774–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937046436&doi=10.1073%252fpnas.1503395112&partnerID=40&md5=b640a9f8759808ea72cc274ad2252598

77.

Mann A, Smoum R, Trembovler V, Alexandrovich A, Breuer A, Mechoulam R, et al. Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury. Journal of Neuroimmune Pharmacology [Internet]. 2015;10(2):356–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84931009191&doi=10.1007%252fs11481-015-9595-z&partnerID=40&md5=6c5507d5172409d93d9c6bbd4c1657d4

78.

Maccarrone M, Bab I, Bíró T, Cabral GA, Dey SK, Di Marzo V, et al. Endocannabinoid signaling at the periphery: 50 years after THC. Trends in Pharmacological Sciences [Internet]. 2015;36(5):277–96. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939990598&doi=10.1016%252fj.tips.2015.02.008&partnerID=40&md5=dc093b27826aaf68fd053e1c74e98017

79.

Sticht MA, Jacklin DL, Mechoulam R, Parker LA, Winters BD. Intraperirhinal cortex administration of the synthetic cannabinoid, HU210, disrupts object recognition memory in rats. NeuroReport [Internet]. 2015;26(5):258–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84924981967&doi=10.1097%252fWNR.0000000000000338&partnerID=40&md5=2401ad05a7cdd60f3b3ea503c2ce1b3e

80.

Hao E, Mukhopadhyay P, Cao Z, Erdélyi K, Holovac E, Liaudet L, et al. Cannabidiol protects against doxorubicin-induced cardiomyopathy by modulating mitochondrial function and biogenesis. Molecular Medicine [Internet]. 2015;21:38–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930678410&doi=10.2119%252fmolmed.2014.00261&partnerID=40&md5=474844bd085a85e49d6cf1dc51781edd

81.

Mechoulam R. The Endocannabinoid System: A Look Back and Ahead. Handbook of experimental pharmacology [Internet]. 2015;231:vii–ix. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953342818&partnerID=40&md5=1f715541ffc6d3d51c4d7793fdb75a70

82.

Di Marzo V, Piscitelli F, Mechoulam R. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handbook of Experimental Pharmacology [Internet]. 2015;203:75–104. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84924037328&doi=10.1007%252f978-3-642-17214-4_4&partnerID=40&md5=72d3b4e0f9b279c24223febe3e494df6

83.

Wasserman E, Tam J, Mechoulam R, Zimmer A, Maor G, Bab I. CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Δ9-tetrahydrocannabinol. Annals of the New York Academy of Sciences [Internet]. 2015;1335(1):110–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920431944&doi=10.1111%252fnyas.12642&partnerID=40&md5=467128e8774d47cc9676d24b194dfb66

84.

Mechoulam R, Hanuš LO, Pertwee R, Howlett AC. Early phytocannabinoid chemistry to endocannabinoids and beyond. Nature Reviews Neuroscience [Internet]. 2014;15(11):757–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908133711&doi=10.1038%252fnrn3811&partnerID=40&md5=41e6ee6fe80741a3815509edc40fc5c1

85.

Mechoulam R. Looking ahead after 50 years of research on cannabinoids [Internet]. Cannabinoids. 2014. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84947567839&doi=10.1002%252f9781118451281.ch1&partnerID=40&md5=33220945fe93fc1f80014cd5cfef63a8

86.

Mechoulam R. Foreword [Internet]. The Handbook of Cannabis Therapeutics: From Bench to Bedside. 2014. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118338287&doi=10.1300%252f5741_c&partnerID=40&md5=92dca4630815ba683aa597a52e8c7e53

87.

Hanuš L, Shohami E, Bab I, Mechoulam R. N-Acyl amino acids and their impact on biological processes. BioFactors [Internet]. 2014;40(4):381–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84906791330&doi=10.1002%252fbiof.1166&partnerID=40&md5=19371391d979d2d5b0772e4340051ac7

88.

Roitman P, Mechoulam R, Cooper-Kazaz R, Shalev A. Preliminary, open-label, pilot study of add-on oral Δ9- tetrahydrocannabinol in chronic post-traumatic stress disorder. Clinical Drug Investigation [Internet]. 2014;34(8):587–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904573718&doi=10.1007%252fs40261-014-0212-3&partnerID=40&md5=44bb1b8497ebc03e9a5645f2f4cce097

89.

Kaminitz A, Barzilay R, Segal H, Taler M, Offen D, Gil-Ad I, et al. Dominant negative DISC1 mutant mice display specific social behaviour deficits and aberration in BDNF and cannabinoid receptor expression. World Journal of Biological Psychiatry [Internet]. 2014;15(1):76–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84892398426&doi=10.3109%252f15622975.2013.841993&partnerID=40&md5=99d979ab0f6729e3bea9e6479a7a146f

90.

Maslov LN, Lishmanov YuB, Oeltgen P, Pei JM, Krylatov AV, Barzakh EI, et al. Effects of preconditioning on coronary perfusion in cardiac ischemia and reperfusion. Neuroscience and Behavioral Physiology [Internet]. 2013;43(9):1039–48. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890439127&doi=10.1007%252fs11055-013-9848-3&partnerID=40&md5=a7c00edcbffc7fb076afdc455f383eff

91.

Maslov LN, Headrick JP, Mechoulam R, Krylatov AV, Lishmanov AYu, Barzakh EI, et al. The role of receptor transactivation in the cardioprotective effects of preconditioning and postconditioning. Neuroscience and Behavioral Physiology [Internet]. 2013;43(9):1015–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890434394&doi=10.1007%252fs11055-013-9844-7&partnerID=40&md5=1ffe72cd9343d3e3a31cd15e3e7fc523

92.

Mechoulam R, Shohami E. HU-211: A cannabinoid neuroprotective agent [Internet]. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential. 2013. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071748701&partnerID=40&md5=ed08fbe23d63b783b883a91417f4dd49

93.

Cohen-Yeshurun A, Willner D, Trembovler V, Alexandrovich A, Mechoulam R, Shohami E, et al. N-arachidonoyl-L-serine (AraS) possesses proneurogenic properties in vitro and in vivo after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism [Internet]. 2013;33(8):1242–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881142050&doi=10.1038%252fjcbfm.2013.75&partnerID=40&md5=fdda3b09e7efa6bc2309ff4e37e527f1

94.

Fernández-Ruiz J, Sagredo O, Pazos MR, García C, Pertwee R, Mechoulam R, et al. Cannabidiol for neurodegenerative disorders: Important new clinical applications for this phytocannabinoid? British Journal of Clinical Pharmacology [Internet]. 2013;75(2):323–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872256489&doi=10.1111%252fj.1365-2125.2012.04341.x&partnerID=40&md5=4dd5b3885ef8e897187897c6c87fbbf2

95.

Mechoulam R, Parker L. Towards a better cannabis drug. British Journal of Pharmacology [Internet]. 2013;170(7):1363–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84887813580&doi=10.1111%252fbph.12400&partnerID=40&md5=b638b88ab390df45adb3bd502b24daca

96.

Espejo-Porras F, Fernández-Ruiz J, Pertwee RG, Mechoulam R, García C. Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors. Neuropharmacology [Internet]. 2013;75:155–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84883026511&doi=10.1016%252fj.neuropharm.2013.07.024&partnerID=40&md5=47cbf119298af2a486244c76e4e805e5

97.

Mechoulam R, Parker LA. The endocannabinoid system and the brain. Annual Review of Psychology [Internet]. 2013;64:21–47. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872156419&doi=10.1146%252fannurev-psych-113011-143739&partnerID=40&md5=d6aa2c681751c29028d582991b25784a

98.

Limebeer CL, Rock EM, Mechoulam R, Parker LA. The anti-nausea effects of CB1 agonists are mediated by an action at the visceral insular cortex. British Journal of Pharmacology [Internet]. 2012;167(5):1126–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84867317282&doi=10.1111%252fj.1476-5381.2012.02066.x&partnerID=40&md5=d762152642dda635342437479b995c4e

99.

Mecha M, Torrao AS, Mestre L, Carrillo-Salinas FJ, Mechoulam R, Guaza C. Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress. Cell Death and Disease [Internet]. 2012;3(6):e331. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863468579&doi=10.1038%252fcddis.2012.71&partnerID=40&md5=bd82792f0389265314ed49bf2854a469

100.

Sticht MA, Long JZ, Rock EM, Limebeer CL, Mechoulam R, Cravatt BF, et al. Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats. British Journal of Pharmacology [Internet]. 2012;165(8):2425–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859067302&doi=10.1111%252fj.1476-5381.2011.01407.x&partnerID=40&md5=83332c3fcad4ef06931bf9843ac65743

101.

Horváth B, Magid L, Mukhopadhyay P, Bátkai S, Rajesh M, Park O, et al. A new cannabinoid CB 2receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. British Journal of Pharmacology [Internet]. 2012;165(8):2462–78. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859029863&doi=10.1111%252fj.1476-5381.2011.01381.x&partnerID=40&md5=24e2340c3a449f46b8da1a7090828d0b

102.

Rock EM, Bolognini D, Limebeer CL, Cascio MG, Anavi-Goffer S, Fletcher PJ, et al. Cannabidiol, a nonpsychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT 1A somatodendritic autoreceptors in the dorsal raphe nucleus. British Journal of Pharmacology [Internet]. 2012;165(8):2620–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-83255165010&doi=10.1111%252fj.1476-5381.2011.01621.x&partnerID=40&md5=90439dc045179e56ca548db5ba48e5f4

103.

Maslov LN, Headrick JP, Mechoulam R, Krylatov AV, Lishmanov AI, Barzakh EI, et al. [Role of receptor transactivation in the cardioprotective effects of preconditioning and postconditioning]. Rossiǐskii fiziologicheskiǐ zhurnal imeni IM Sechenova / Rossiǐskaia akademiia nauk [Internet]. 2012;98(3):305–17. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864394576&partnerID=40&md5=f94bc6683a05e0013981df2b63177e4c

104.

Mechoulam R. Cannabis - A valuable drug that deserves better treatment. Mayo Clinic Proceedings [Internet]. 2012;87(2):107–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856682293&doi=10.1016%252fj.mayocp.2011.12.002&partnerID=40&md5=7ee61d4b521478a761f2e5daeeec0d36

105.

Brown I, Wahle KWJ, Cascio MG, Smoum-Jaouni R, Mechoulam R, Pertwee RG, et al. Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. Prostaglandins Leukotrienes and Essential Fatty Acids [Internet]. 2011;85(6):305–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80055068558&doi=10.1016%252fj.plefa.2011.09.007&partnerID=40&md5=039c52f2c3fac17f8b700a55581a7899

106.

Shohami E, Cohen-Yeshurun A, Magid L, Algali M, Mechoulam R. Endocannabinoids and traumatic brain injury. British Journal of Pharmacology [Internet]. 2011;163(7):1402–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960333360&doi=10.1111%252fj.1476-5381.2011.01343.x&partnerID=40&md5=c6b91eb886f732c1e58575286a9ecdd0

107.

Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gõmez-Cañas M, Valdeolivas S, et al. Prospects for cannabinoid therapies in basal ganglia disorders. British Journal of Pharmacology [Internet]. 2011;163(7):1365–78. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960317325&doi=10.1111%252fj.1476-5381.2011.01365.x&partnerID=40&md5=e6c64226d3a4e9a2b7cf898c662033ef

108.

Bab I, Smoum R, Bradshaw H, Mechoulam R. Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family. British Journal of Pharmacology [Internet]. 2011;163(7):1441–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960313458&doi=10.1111%252fj.1476-5381.2011.01474.x&partnerID=40&md5=e057e78e52fb0d5f417a9bf271c0abfd

109.

Rock EM, Limebeer CL, Mechoulam R, Piomelli D, Parker LA. Erratum: The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat (Psychopharmacology DOI: 10.1007/s00213-007-0970-1). Psychopharmacology [Internet]. 2011;216(1):149. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960011512&doi=10.1007%252fs00213-011-2332-2&partnerID=40&md5=14390d4944dc9451f1745f4860f39d44

110.

Rock EM, Goodwin JM, Limebeer CL, Breuer A, Pertwee RG, Mechoulam R, et al. Interaction between non-psychotropic cannabinoids in marihuana: Effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. Psychopharmacology [Internet]. 2011;215(3):505–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80052341043&doi=10.1007%252fs00213-010-2157-4&partnerID=40&md5=fbdb8972adb806cb6fa5c7eaba3d83d4

111.

Martín-Moreno AM, Reigada D, Ramírez BG, Mechoulam R, Innamorato N, Cuadrado A, et al. Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: Relevance to alzheimer’s disease. Molecular Pharmacology [Internet]. 2011;79(6):964–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79956293339&doi=10.1124%252fmol.111.071290&partnerID=40&md5=a2c1da9af8e965d22122c33836c5ddb4

112.

Lourbopoulos A, Grigoriadis N, Lagoudaki R, Touloumi O, Polyzoidou E, Mavromatis I, et al. Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis. Brain Research [Internet]. 2011;1390:126–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955610081&doi=10.1016%252fj.brainres.2011.03.020&partnerID=40&md5=59b53bd2c3f07abc17cc8a11c5e52c10

113.

Mukhopadhyay P, Rajesh M, Horváth B, Bátkai S, Park O, Tanchian G, et al. Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. Free Radical Biology and Medicine [Internet]. 2011;50(10):1368–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955475920&doi=10.1016%252fj.freeradbiomed.2011.02.021&partnerID=40&md5=833d71b8daa9abd01c3aab77b8ff39de

114.

Avraham Y, Grigoriadis NC, Poutahidis T, Vorobiev L, Magen I, Ilan Y, et al. Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. British Journal of Pharmacology [Internet]. 2011;162(7):1650–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952378224&doi=10.1111%252fj.1476-5381.2010.01179.x&partnerID=40&md5=163a9170c1347954538443391126fd8b

115.

Pacher P, Mechoulam R. Is lipid signaling through cannabinoid 2 receptors part of a protective system? Progress in Lipid Research [Internet]. 2011;50(2):193–211. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952198989&doi=10.1016%252fj.plipres.2011.01.001&partnerID=40&md5=1ecfaf0cbeba4e4dcd06b3dfc260dca1

116.

Murillo-Rodríguez E, Palomero-Rivero M, Millán-Aldaco D, Mechoulam R, Drucker-Colín R. Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. Life Sciences [Internet]. 2011;88(11–12):504–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952438369&doi=10.1016%252fj.lfs.2011.01.013&partnerID=40&md5=6d83498670fed988fbec212d3c4aca4b

117.

Ofek O, Attar-Namdar M, Kram V, Dvir-Ginzberg M, Mechoulam R, Zimmer A, et al. CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts. Journal of Bone and Mineral Research [Internet]. 2011;26(2):308–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79251500011&doi=10.1002%252fjbmr.228&partnerID=40&md5=4c42575d0723c2a269c1d69194760cee

118.

Cohen-Yeshurun A, Trembovler V, Alexandrovich A, Ryberg E, Greasley PJ, Mechoulam R, et al. N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis. Journal of Cerebral Blood Flow and Metabolism [Internet]. 2011;31(8):1768–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027934703&doi=10.1038%252fjcbfm.2011.53&partnerID=40&md5=7f6e3b74d2c686be3f7a018d286c1691

119.

Mechoulam R, Hanus L. Other cannabinoids [Internet]. Marijuana and Madness: Second Edition. 2011. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923533639&doi=10.1017%252fCBO9780511706080.003&partnerID=40&md5=59e03dea5892874a06971cfa70b14a14

120.

Di Marzo V, Piscitelli F, Mechoulam R. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handbook of Experimental Pharmacology [Internet]. 2011;203:75–104. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79955632246&doi=10.1007%252f978-3-642-17214-4_4&partnerID=40&md5=c1738af9dd79f50fa5dc244e4a3a776f

121.

Rajesh M, Mukhopadhyay P, Btkai S, Patel V, Saito K, Matsumoto S, et al. Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. Journal of the American College of Cardiology [Internet]. 2010;56(25):2115–25. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649984380&doi=10.1016%252fj.jacc.2010.07.033&partnerID=40&md5=8935055e960adb1b7cbb948c87dea564

122.

Pertwee RG, Howlett AC, Abood ME, Alexander SPH, Di Marzo V, Elphick MR, et al. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB1 and CB2. Pharmacological Reviews [Internet]. 2010;62(4):588–631. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650120798&doi=10.1124%252fpr.110.003004&partnerID=40&md5=914ee575bef66b466af7627f4aedc095

123.

Smoum R, Bar A, Tan B, Milman G, Attar-Namdar M, Ofek O, et al. Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(41):17710–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78049275914&doi=10.1073%252fpnas.0912479107&partnerID=40&md5=37e089a4c2100ccd264a581ede4c4d0a

124.

Pope C, Mechoulam R, Parsons L. Endocannabinoid signaling in neurotoxicity and neuroprotection. NeuroToxicology [Internet]. 2010;31(5):562–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956228507&doi=10.1016%252fj.neuro.2009.12.002&partnerID=40&md5=7d6383ff8f1576e9a995f13fdeacc6bc

125.

Brown I, Cascio MG, Wahle KW, Smoum R, Mechoulam R, Ross RA, et al. Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. Carcinogenesis [Internet]. 2010;31(9):1584–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956278506&doi=10.1093%252fcarcin%252fbgq151&partnerID=40&md5=920f208ff07ef279bc13bfdf3bcc0b07

126.

Mechoulam R. Endocannabinoids and psychiatric disorders: The road ahead [Endocanabinoides e transtornos psiquiátricos: A estrada à frente]. Revista Brasileira de Psiquiatria [Internet]. 2010;32(SUPPL. 1):S5–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952198851&partnerID=40&md5=6826f41ddbe90d72f10e37dc48d4e0c4

127.

Hanuš LO, Mechoulam R. Novel natural and synthetic ligands of the endocannabinoid system. Current Medicinal Chemistry [Internet]. 2010;17(14):1341–59. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950633627&doi=10.2174%252f092986710790980096&partnerID=40&md5=f1b9068b6096c98b53f0ee9432eee7a5

128.

Magen I, Avraham Y, Ackerman Z, Vorobiev L, Mechoulam R, Berry EM. Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT 1A receptor activation. British Journal of Pharmacology [Internet]. 2010;159(4):950–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77249134168&doi=10.1111%252fj.1476-5381.2009.00589.x&partnerID=40&md5=76e7aae62e9ff9b0a528958b196ef7e2

129.

Moussaieff A, Mechoulam R. Boswellia resin: From religious ceremonies to medical uses; a review of in-vitro, in-vivo and clinical trials. Journal of Pharmacy and Pharmacology [Internet]. 2009;61(10):1281–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-74949117177&doi=10.1211%252fjpp%252f61.10.0003&partnerID=40&md5=f63dcd3674188dde58a414f16569d94a

130.

Avraham Y, Grigoriadis NC, Magen I, Poutahidis T, Vorobiav L, Zolotarev O, et al. Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice. British Journal of Pharmacology [Internet]. 2009;158(3):896–906. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350047068&doi=10.1111%252fj.1476-5381.2009.00368.x&partnerID=40&md5=a918c576958b720f556763bdc3956e9b

131.

Magen I, Avraham Y, Ackerman Z, Vorobiev L, Mechoulam R, Berry EM. Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. Journal of Hepatology [Internet]. 2009;51(3):528–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-68049129534&doi=10.1016%252fj.jhep.2009.04.021&partnerID=40&md5=8f41454570485560b2a464ce25afa0a3

132.

Sagredo O, González S, Aroyo I, Pazos MR, Benito C, Lastres-Becker I, et al. Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington’s disease. GLIA [Internet]. 2009;57(11):1154–67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-69649091696&doi=10.1002%252fglia.20838&partnerID=40&md5=d43a3a4f2e7ba21b3e48eadabc0468f1

133.

Avraham Y, Zolotarev O, Grigoriadis NC, Pautahidis T, Magen I, Vorobiav L, et al. Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice (American Journal of Gastroenterology (2009) 103, (3047-3056) DOI: 10.1111/j.1572-0241.2008.02155.x). American Journal of Gastroenterology [Internet]. 2009;104(3):801. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-61949226426&doi=10.1038%252fajg.2009.98&partnerID=40&md5=e1520af5ec2551b35b11d8bc953f908a

134.

Izzo AA, Borrelli F, Capasso R, Di Marzo V, Mechoulam R. Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends in Pharmacological Sciences [Internet]. 2009;30(10):515–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-70349189518&doi=10.1016%252fj.tips.2009.07.006&partnerID=40&md5=47fedd9031f98f2fc1e66c8c2e5918e8

135.

Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Mechoulam R, Drucker-Colín R. The Nonpsychoactive Cannabis Constituent Cannabidiol Is a Wake-Inducing Agent. Behavioral Neuroscience [Internet]. 2008;122(6):1378–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-57049154057&doi=10.1037%252fa0013278&partnerID=40&md5=820e0af81b24dd3481e4d578e53f5529

136.

Patinkin D, Milman G, Breuer A, Fride E, Mechoulam R. Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation. European Journal of Pharmacology [Internet]. 2008;595(1–3):1–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-52049093883&doi=10.1016%252fj.ejphar.2008.05.002&partnerID=40&md5=101148193e67cb35d1586da5b249eb35

137.

Galanti G, Fisher T, Kventsel I, Shoham J, Gallily R, Mechoulam R, et al. Δ9-Tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. Acta Oncologica [Internet]. 2008;47(6):1062–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-51449092478&doi=10.1080%252f02841860701678787&partnerID=40&md5=f4f08c8e0de357240143f749585b03ca

138.

Magen I, Avraham Y, Berry E, Mechoulam R. Endocannabinoids in liver disease and hepatic encephalopathy. Current Pharmaceutical Design [Internet]. 2008;14(23):2362–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-52949141093&doi=10.2174%252f138161208785740063&partnerID=40&md5=3bf6b1432146e0a79c004c6728b72f75

139.

Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, et al. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. FASEB Journal [Internet]. 2008;22(8):3024–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-48749095422&doi=10.1096%252ffj.07-101865&partnerID=40&md5=fffa6db6c89905a6f8383496b09eddb8

140.

Moussaieff A, Shein NA, Tsenter J, Grigoriadis S, Simeonidou C, Alexandrovich AG, et al. Incensole acetate: A novel neuroprotective agent isolated from Boswellia carterii. Journal of Cerebral Blood Flow and Metabolism [Internet]. 2008;28(7):1341–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-46049088322&doi=10.1038%252fjcbfm.2008.28&partnerID=40&md5=b915e9e392d0bcb046a7fa280f75c5a2

141.

Weinstein A, Brickner O, Lerman H, Greemland M, Bloch M, Lester H, et al. A study investigating the acute dose-response effects of 13 mg and 17 mg Δ 9- tetrahydrocannabinol on cognitive-motor skills, subjective and autonomic measures in regular users of marijuana. Journal of Psychopharmacology [Internet]. 2008;22(4):441–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-47249139115&doi=10.1177%252f0269881108088194&partnerID=40&md5=0d15b3c4752e19be29e0d5a51ab936df

142.

Palazuelos J, Davoust N, Julien B, Hatterer E, Aguado T, Mechoulam R, et al. The CB2 cannabinoid receptor controls myeloid progenitor trafficking: Involvement in the pathogenesis of an animal model of multiple sclerosis. Journal of Biological Chemistry [Internet]. 2008;283(19):13320–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-45149123400&doi=10.1074%252fjbc.M707960200&partnerID=40&md5=439474c1ddaddc2bff3e87caa52e0df9

143.

Ronen A, Gershon P, Drobiner H, Rabinovich A, Bar-Hamburger R, Mechoulam R, et al. Effects of THC on driving performance, physiological state and subjective feelings relative to alcohol. Accident Analysis and Prevention [Internet]. 2008;40(3):926–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-42749090485&doi=10.1016%252fj.aap.2007.10.011&partnerID=40&md5=9cf5e278ffa89cb72e898abba2b21346

144.

Bermúdez-Silva FJ, Suárez J, Baixeras E, Cobo N, Bautista D, Cuesta-Muñoz AL, et al. Presence of functional cannabinoid receptors in human endocrine pancreas. Diabetologia [Internet]. 2008;51(3):476–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-39049091518&doi=10.1007%252fs00125-007-0890-y&partnerID=40&md5=9e62ba7a2c07c8ac2f1643c98f18beab

145.

McHugh D, Tanner C, Mechoulam R, Pertwee RG, Ross RA. Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: Evidence for a site distinct from CB1 and CB 2. Molecular Pharmacology [Internet]. 2008;73(2):441–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38549130466&doi=10.1124%252fmol.107.041863&partnerID=40&md5=57608f80b3a8cb098a8fc1c74ab14f5e

146.

Avraham Y, Zolotarev O, Grigoriadis NC, Pautahidis T, Magen I, Vorobiav L, et al. Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice. American Journal of Gastroenterology [Internet]. 2008;103(12):3047–56. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-58149402426&doi=10.1111%252fj.1572-0241.2008.02155.x&partnerID=40&md5=f3410ac912421a60b871c6675857623e

147.

Rock EM, Limebeer CL, Mechoulam R, Piomelli D, Parker LA. The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat. Psychopharmacology [Internet]. 2008;196(3):389–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38949121027&doi=10.1007%252fs00213-007-0970-1&partnerID=40&md5=4abd37a0ae18c2de94e8dcd926896f79

148.

Weinstein A, Brickner O, Lerman H, Greemland M, Bloch M, Lester H, et al. Brain imaging study of the acute effects of Δ9- tetrahydrocannabinol (THC) on attention and motor coordination in regular users of marijuana. Psychopharmacology [Internet]. 2008;196(1):119–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38149092463&doi=10.1007%252fs00213-007-0940-7&partnerID=40&md5=27a5eeabd590c0819f52f18f56ab95f6

149.

Tam J, Trembovler V, Di Marzo V, Petrosino S, Leo G, Alexandrovich A, et al. The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. FASEB Journal [Internet]. 2008;22(1):285–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38049132712&doi=10.1096%252ffj.06-7957com&partnerID=40&md5=107c229abbe659481cdc46fe0960d31d

150.

Weiss L, Zeira M, Reich S, Slavin S, Raz I, Mechoulam R, et al. Cannabidiol arrests onset of autoimmune diabetes in NOD mice. Neuropharmacology [Internet]. 2008;54(1):244–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37349096614&doi=10.1016%252fj.neuropharm.2007.06.029&partnerID=40&md5=9dbf3de52077d8533b9ef43743488cf4

151.

Kogan NM, Mechoulam R. Cannabinoids in health and disease. Dialogues in Clinical Neuroscience [Internet]. 2007;9(4):413–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38849111946&partnerID=40&md5=c7b59946f823a6a241c8e3eddc528e7b

152.

Durst R, Danenberg H, Gallily R, Mechoulam R, Meir K, Grad E, et al. Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury. American Journal of Physiology - Heart and Circulatory Physiology [Internet]. 2007;293(6):H3602–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-36849091565&doi=10.1152%252fajpheart.00098.2007&partnerID=40&md5=36337844c0f92faddc0864e7c24d1f9e

153.

Moussaieff A, Shohami E, Kashman Y, Fride E, Schmitz ML, Renner F, et al. Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-κB activation. Molecular Pharmacology [Internet]. 2007;72(6):1657–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-36348955094&doi=10.1124%252fmol.107.038810&partnerID=40&md5=69a209dedd60fbd72838e541466ee20f

154.

Mechoulam R. Endocannabinoids: Functional roles and therapeutic opportunities [Gli endocannabinoidi: Ruoli funzionali e opportunità terapeutiche]. Giornale di Neuropsicofarmacologia [Internet]. 2007;29(4):99–101. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-51149121455&partnerID=40&md5=0fc9f6413749262a2805eb59a506ea35

155.

Mechoulam R, Peters M, Murillo-Rodriguez E, Hanuš LO. Cannabidiol - Recent advances. Chemistry and Biodiversity [Internet]. 2007;4(8):1678–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548515940&doi=10.1002%252fcbdv.200790147&partnerID=40&md5=6d537056e321d6637aec25b410f863cb

156.

Sagredo O, Ramos JA, Decio A, Mechoulam R, Fernández-Ruiz J. Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors. European Journal of Neuroscience [Internet]. 2007;26(4):843–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547984234&doi=10.1111%252fj.1460-9568.2007.05717.x&partnerID=40&md5=492d4120ef65fc540226477c4eebefc2

157.

Dagon Y, Avraham Y, Ilan Y, Mechoulam R, Berry EM. Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase. FASEB Journal [Internet]. 2007;21(10):2431–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547823575&doi=10.1096%252ffj.06-7705com&partnerID=40&md5=fa82c5aa53525430c525082685e261e1

158.

Kogan NM, Schlesinger M, Peters M, Marincheva G, Beeri R, Mechoulam R. A cannabinoid anticancer quinone, HU-331, is more potent and less cardiotoxic than doxorubicin: A comparative in vivo study. Journal of Pharmacology and Experimental Therapeutics [Internet]. 2007;322(2):646–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547092168&doi=10.1124%252fjpet.107.120865&partnerID=40&md5=511d8edac4efc162cd22f86d3e252ed4

159.

Dagon Y, Avraham Y, Link G, Zolotarev O, Mechoulam R, Berry EM. The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells. Neurobiology of Disease [Internet]. 2007;27(2):174–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34447632664&doi=10.1016%252fj.nbd.2007.04.017&partnerID=40&md5=0424ab4633b1be30ed190dd13134b0da

160.

Karsak M, Gaffal E, Date R, Wang-Eckhardt L, Rehnelt J, Petrosino S, et al. Attenuation of allergic contact dermatitis through the endocannabinoid system. Science [Internet]. 2007;316(5830):1494–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250209535&doi=10.1126%252fscience.1142265&partnerID=40&md5=2682d07402dee897f51bcc11b190be4a

161.

García-Arencibia M, González S, de Lago E, Ramos JA, Mechoulam R, Fernández-Ruiz J. Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson’s disease: Importance of antioxidant and cannabinoid receptor-independent properties. Brain Research [Internet]. 2007;1134(1):162–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846401540&doi=10.1016%252fj.brainres.2006.11.063&partnerID=40&md5=ee4000b4609e64da710eb9942286def7

162.

Hanuš L, Mechoulam R. Plant and brain Cannabinoids: The chemistry of major new players in physiology [Internet]. Selected Topics in the Chemistry of Natural Products. 2007. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969165740&doi=10.1142%252f9789812790781_0003&partnerID=40&md5=e138c3382353b1247c20293a1cd22a55

163.

Mechoulam R, Shohami E. Endocannabinoids and traumatic brain injury. Molecular Neurobiology [Internet]. 2007;36(1):68–74. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38449086056&doi=10.1007%252fs12035-007-8008-6&partnerID=40&md5=67e30f8b074c08d5f14b673ee1b5c226

164.

Kogan NM, Schlesinger M, Priel E, Rabinowitz R, Berenshtein E, Chevion M, et al. HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor. Molecular Cancer Therapeutics [Internet]. 2007;6(1):173–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846840690&doi=10.1158%252f1535-7163.MCT-06-0039&partnerID=40&md5=1b8a722c54709e3c333daceb7bd8ea01

165.

Mccarron RM, Chen Y, Tomori T, Strasser A, Mechoulam R, Shohami E, et al. Endothelial-mediated regulation of cerebral microcirculation. Journal of Physiology and Pharmacology [Internet]. 2006;57(SUPPL. 11):133–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34147137204&partnerID=40&md5=1a7c6692813f2c5360d608eacf544364

166.

Palazuelos J, Aguado T, Egia A, Mechoulam R, Guzmán M, Galve-Roperh I. Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation. FASEB Journal [Internet]. 2006;20(13):E1773–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845603466&doi=10.1096%252ffj.06-6164fje&partnerID=40&md5=4f026a6e751e990d2f9bddabd79492cc

167.

Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Mechoulam R, Drucker-Colín R. Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. FEBS Letters [Internet]. 2006;580(18):4337–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746518572&doi=10.1016%252fj.febslet.2006.04.102&partnerID=40&md5=2950da7705966be3675198746fd36dfd

168.

Kogan NM, Blázquez C, Álvarez L, Gallily R, Schlesinger M, Guzmán M, et al. A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. Molecular Pharmacology [Internet]. 2006;70(1):51–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745250125&doi=10.1124%252fmol.105.021089&partnerID=40&md5=3f092530b27268ec801710e8f6f5f45b

169.

Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A, et al. The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. Neurobiology of Disease [Internet]. 2006;22(2):257–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646142292&doi=10.1016%252fj.nbd.2005.11.004&partnerID=40&md5=13ed19f00be1d56805c5727416c3d29e

170.

Mechoulam R, Berry EM, Avraham Y, Di Marzo V, Fride E. Endocannabinoids, feeding and suckling - From our perspective. International Journal of Obesity [Internet]. 2006;30(SUPPL. 1):S24–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33645507624&doi=10.1038%252fsj.ijo.0803274&partnerID=40&md5=d34339f0211892a03f303aa87aae4f7a

171.

Weiss L, Zeira M, Reich S, Har-Noy M, Mechoulam R, Slavin S, et al. Cannabidiol lowers incidence of diabetes in non-obese diabetic mice. Autoimmunity [Internet]. 2006;39(2):143–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646404921&doi=10.1080%252f08916930500356674&partnerID=40&md5=ab304743e2e59e1dbef484fb6032d27b

172.

Milman G, Maor Y, Abu-Lafi S, Horowitz M, Gallily R, Batkai S, et al. N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2006;103(7):2428–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33144473891&doi=10.1073%252fpnas.0510676103&partnerID=40&md5=6f7ef70501c4cb8749535d6d82f62a27

173.

Parker LA, Kwiatkowska M, Mechoulam R. Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting. Physiology and Behavior [Internet]. 2006;87(1):66–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-29144520207&doi=10.1016%252fj.physbeh.2005.08.045&partnerID=40&md5=39a032a3febd81c8f9dd64fe3da3d2bb

174.

Ofek O, Karsak M, Leclerc N, Fogel M, Frenkel B, Wright K, et al. Peripheral cannabinoid receptor, CB2, regulates bone mass. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2006;103(3):696–701. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-31444437185&doi=10.1073%252fpnas.0504187103&partnerID=40&md5=9a3dc56cc7633354e24bf1a0bcf6a73c

175.

Tam J, Ofek O, Fride E, Ledent C, Gabet Y, M̈uller R, et al. Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling. Molecular Pharmacology [Internet]. 2006;70(3):786–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33747598488&doi=10.1124%252fmol.106.026435&partnerID=40&md5=1748226775e4f466933b6e29cd7bfcbe

176.

Kogan NM, Mechoulam R. The chemistry of endocannabinoids. Journal of endocrinological investigation [Internet]. 2006;29(3 Suppl):3–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745502606&partnerID=40&md5=fac6bd1656ed8740782dd71b0b9304d6

177.

Avraham Y, Israeli E, Gabbay E, Okun A, Zolotarev O, Silberman I, et al. Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice. Neurobiology of Disease [Internet]. 2006;21(1):237–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-29144480571&doi=10.1016%252fj.nbd.2005.07.008&partnerID=40&md5=e8c49e4801f97f3882d3b0e1737c98d1

178.

Mechoulam R, Deutsch DG. Toward an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2005;102(49):17541–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-29144482542&doi=10.1073%252fpnas.0508644102&partnerID=40&md5=0b586362abe264f0a28d020aa02462e2

179.

Mechoulam R. Preface. Handbook of Experimental Pharmacology [Internet]. 2005;168:VII–VIII. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884484712&doi=10.1007%252fb137831&partnerID=40&md5=82f02538bdb548aad3ad5335d3f379df

180.

Mechoulam R. Plant cannabinoids: A neglected pharmacological treasure trove. British Journal of Pharmacology [Internet]. 2005;146(7):913–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-28444487445&doi=10.1038%252fsj.bjp.0706415&partnerID=40&md5=dd9ea481ea8571010dceb97dfae9adb7

181.

Moussaieff A, Fride E, Amar Z, Lev E, Steinberg D, Gallily R, et al. The Jerusalem Balsam: From the Franciscan Monastery in the old city of Jerusalem to Martindale 33. Journal of Ethnopharmacology [Internet]. 2005;101(1–3):16–26. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-24644511790&doi=10.1016%252fj.jep.2005.03.028&partnerID=40&md5=d5973e48e75aef36195890fb6655e7d5

182.

Unzicker C, Erberich H, Moldrich G, Woldt H, Bulla J, Mechoulam R, et al. Hippocampal cannabinoid-1 receptor upregulation upon endothelin-B receptor deficiency: A neuroprotective substitution effect? Neurochemical Research [Internet]. 2005;30(10):1305–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-28844435815&doi=10.1007%252fs11064-005-8802-3&partnerID=40&md5=107ceeb792cbf4b1742e4c59a2835abd

183.

Fride E, Suris R, Weidenfeld J, Mechoulam R. Differential response to acute and repeated stress in cannabinoid CB 1 receptor knockout newborn and adult mice. Behavioural Pharmacology [Internet]. 2005;16(5–6):431–40. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-26044434132&doi=10.1097%252f00008877-200509000-00016&partnerID=40&md5=5f66e4812f982e203c8b70b044e7ae7c

184.

Panikashvili D, Mechoulam R, Beni SM, Alexandrovich A, Shohami E. CB1 cannabinoid receptors are involved in neuroprotection via NF-κB inhibition. Journal of Cerebral Blood Flow and Metabolism [Internet]. 2005;25(4):477–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-17044364809&doi=10.1038%252fsj.jcbfm.9600047&partnerID=40&md5=67decf1e8d49264381cb5d73b8a5d29c

185.

Hanuš LO, Tchilibon S, Ponde DE, Breuer A, Fride E, Mechoulam R. Enantiomeric cannabidiol derivatives: Synthesis and binding to cannabinoid receptors. Organic and Biomolecular Chemistry [Internet]. 2005;3(6):1116–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-16244383829&doi=10.1039%252fb416943c&partnerID=40&md5=59d5067e0cf219aeebb2f9686754543a

186.

Avraham Y, Menachem AB, Okun A, Zlotarav O, Abel N, Mechoulam R, et al. Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice. Brain Research Bulletin [Internet]. 2005;65(2):117–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-14844328019&doi=10.1016%252fj.brainresbull.2004.12.002&partnerID=40&md5=747dc62ed99dc2004994276d3b4b5b9a

187.

Sarne Y, Mechoulam R. Cannabinoids: Between neuroprotection and neurotoxicity. Current Drug Targets: CNS and Neurological Disorders [Internet]. 2005;4(6):677–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-28944437048&doi=10.2174%252f156800705774933005&partnerID=40&md5=7b2bb1b3a0726f087e1ba8977c52b154

188.

Mechoulam R, Sumariwalla PF, Feldmann M, Gallily R. Cannabinoids in models of chronic inflammatory conditions. Phytochemistry Reviews [Internet]. 2005;4(1):11–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-23944434153&doi=10.1007%252fs11101-004-1534-1&partnerID=40&md5=a5c94c199659489202a99f6ec7121f72

189.

Maccarrone M, Fride E, Bisogno T, Bari M, Cascio MG, Battista N, et al. Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. Molecular Human Reproduction [Internet]. 2005;11(1):21–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-20044388537&doi=10.1093%252fmolehr%252fgah130&partnerID=40&md5=c7a8c20666f7b08ea9a2358e0be42ffa

190.

Pertwee RG, Thomas A, Stevenson LA, Maor Y, Mechoulam R. Evidence that (-)-7-hydroxy-4′-dimethylheptyl-cannabidiol activates a non-CB1, non-CB2, non-TRPV1 target in the mouse vas deferens. Neuropharmacology [Internet]. 2005;48(8 SPEC. ISS.):1139–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-19444386763&doi=10.1016%252fj.neuropharm.2005.01.010&partnerID=40&md5=6e9dc3c5f6787640dddd7ccefa5f58b4

191.

Makriyannis A, Mechoulam R, Piomelli D. Therapeutic opportunities through modulation of the endocannabinoid system. Neuropharmacology [Internet]. 2005;48(8 SPEC. ISS.):1068–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-19444372967&doi=10.1016%252fj.neuropharm.2005.03.012&partnerID=40&md5=4b26ce60081a1a7c2d8fbd26bfa05e5f

192.

Lastres-Becker I, Molina-Holgado F, Ramos JA, Mechoulam R, Fernández-Ruiz J. Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: Relevance to Parkinson’s disease. Neurobiology of Disease [Internet]. 2005;19(1–2):96–107. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-17444370570&doi=10.1016%252fj.nbd.2004.11.009&partnerID=40&md5=c6e6cdc58e74cb947a98a674a3063ad9

193.

Fride E, Feigin C, Ponde DE, Breuer A, Hanuš L, Arshavsky N, et al. (+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only. European Journal of Pharmacology [Internet]. 2004;506(2):179–88. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-9944240860&doi=10.1016%252fj.ejphar.2004.10.049&partnerID=40&md5=173934e41fe0a8226db3fd33ba84cb01

194.

Golech SA, McCarron RM, Chen Y, Bembry J, Lenz F, Mechoulam R, et al. Human brain endothelium: Coexpression and function of vanilloid and endocannabinoid receptors. Molecular Brain Research [Internet]. 2004;132(1):87–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-8844260491&doi=10.1016%252fj.molbrainres.2004.08.025&partnerID=40&md5=efeb1e36bcfd5b4b8f8b7f6fcd616e3f

195.

Navab R, Aingorn H, Fallavollita L, Sallon S, Mechoulam R, Ginsburg I, et al. PADMA-28, a traditional Tibetan herbal preparation, blocks cellular responses to bFGF and IGF-I. Inflammopharmacology [Internet]. 2004;12(4):373–89. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-21344457918&doi=10.1163%252f1568560043696227&partnerID=40&md5=a0fcc0d0332d36ccdab79f05e26b5f19

196.

Parker LA, Burton P, Sorge RE, Yakiwchuk C, Mechoulam R. Effect of low doses of Δ9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats. Psychopharmacology [Internet]. 2004;175(3):360–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-5444220592&doi=10.1007%252fs00213-004-1825-7&partnerID=40&md5=7409f0d1570981d033eff7fe22f14442

197.

Kogan NM, Rabinowitz R, Levi P, Gibson D, Sandor P, Schlesinger M, et al. Synthesis and antitumor activity of quinonoid derivatives of cannabinoids. Journal of Medicinal Chemistry [Internet]. 2004;47(15):3800–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3142618434&doi=10.1021%252fjm040042o&partnerID=40&md5=72c0dcd4667700cde4e5e69d4c434288

198.

Sumariwalla PF, Gallily R, Tchilibon S, Fride E, Mechoulam R, Feldmann M. A Novel Synthetic, Nonpsychoactive Cannabinoid Acid (HU-320) with Antiinflammatory Properties in Murine Collagen-Induced Arthritis. Arthritis and Rheumatism [Internet]. 2004;50(3):985–98. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-1542283741&doi=10.1002%252fart.20050&partnerID=40&md5=0f4495e5498196708bae92187d4e0713

199.

Mechoulam R. The promise of advances in the field of endocannabinoids. Neuroendocrinology letters [Internet]. 2004;25(1–2):11–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242807557&partnerID=40&md5=03a37bcf401fe0a0c09454b0f2285cd6

200.

Kwiatkowska M, Parker LA, Burton P, Mechoulam R. A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew). Psychopharmacology [Internet]. 2004;174(2):254–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3142697890&doi=10.1007%252fs00213-003-1739-9&partnerID=40&md5=7902cf1fad1cb110c3fb6b0d48f2d616

201.

Parker LA, Kwiatkowska M, Burton P, Mechoulam R. Effect of cannabinoids on lithium-induced vomiting in the Suncus murinus (house musk shrew). Psychopharmacology [Internet]. 2004;171(2):156–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-1642578318&doi=10.1007%252fs00213-003-1571-2&partnerID=40&md5=ba652d4af2c8d08052a93c21f2df00ef

202.

Burstein S, Zurier RB, Sumariwalla PF, Feldmann M, Gallily R, Mechoulam R, et al. Pain reduction and lack of psychotropic effects with ajulemic acid: Comment on the article by Sumariwalla et al [4] (multiple letters). Arthritis and Rheumatism [Internet]. 2004;50(12):4078–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-10444285327&doi=10.1002%252fart.20805&partnerID=40&md5=deb7891380544994bebb1efbf9ba593c

203.

Lodzki M, Godin B, Rakou L, Mechoulam R, Gallily R, Touitou E. Cannabidiol - Transdermal delivery and anti-inflammatory effect in a murine model. Journal of Controlled Release [Internet]. 2003;93(3):377–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0344009662&doi=10.1016%252fj.jconrel.2003.09.001&partnerID=40&md5=e5ede16bafb29db8d7b04b718b92803b

204.

Mechoulam R, Lichtman AH. Stout guards of the central nervous system. Science [Internet]. 2003;302(5642):65+67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141754171&doi=10.1126%252fscience.1091256&partnerID=40&md5=d6cc02d9cc0873406ba105b8fe2f874f

205.

Gallily R, Even-Chen T, Katzavian G, Lehmann D, Dagan A, Mechoulam R. γ-Irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. Leukemia and Lymphoma [Internet]. 2003;44(10):1767–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141758489&doi=10.1080%252f1042819031000103917&partnerID=40&md5=e366889fd1af7ba6978e1cf1e92534a3

206.

Hanuš L, Avraham Y, Ben-Shushan D, Zolotarev O, Berry EM, Mechoulam R. Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. Brain Research [Internet]. 2003;983(1–2):144–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0043162058&doi=10.1016%2fS0006-8993%2803%2903046-4&partnerID=40&md5=d92ecc6042354f3b6a6795c77c7e559e

207.

Gilgun-Sherki Y, Melamed E, Mechoulam R, Offen D. The CB1 cannabinoid receptor agonist, HU-210, reduces levodopa-induced rotations in 6-hydroxydopamine-lesioned rats. Pharmacology and Toxicology [Internet]. 2003;93(2):66–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0042530283&doi=10.1034%252fj.1600-0773.2003.930202.x&partnerID=40&md5=d6640d8577b80e6a1d100071335a5393

208.

Leker RR, Gai N, Mechoulam R, Ovadia H. Drug-induced hypothermia reduces ischemic damage: Effects of the cannabinoid HU-210. Stroke [Internet]. 2003;34(8):2000–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0041621495&doi=10.1161%252f01.STR.0000079817.68944.1E&partnerID=40&md5=afc3a18a79163ea4fcbb310e1b132ad1

209.

Mechoulam R, Parker L. Cannabis and alcohol - A close friendship. Trends in Pharmacological Sciences [Internet]. 2003;24(6):266–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037666070&doi=10.1016%2fS0165-6147%2803%2900107-X&partnerID=40&md5=c9eb94cb6d0929155f3428d5ef215d87

210.

Fride E, Foox A, Rosenberg E, Faigenboim M, Cohen V, Barda L, et al. Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: Evidence for a “CB3” receptor. European Journal of Pharmacology [Internet]. 2003;461(1):27–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037423029&doi=10.1016%2fS0014-2999%2803%2901295-0&partnerID=40&md5=c9ed22ec4478bc47d8e2c4cf614f4985

211.

Spatz M, McCarron RM, Shohami E, Panikashvili D, Chen Y, Golcch S, et al. Antioxidant properties of the vasoactive endocannabinoid, 2-arachidonoyl glycerol (2-AG). Acta Neurochirurgica, Supplementum [Internet]. 2003;(86):271–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950436388&doi=10.1007%252f978-3-7091-0651-8_59&partnerID=40&md5=192ba0767ee9d568e880739b295a052f

212.

Parker LA, Mechoulam R. Cannabinoid Agonists and Antagonists Modulate Lithium-induced Conditioned Gaping in Rats. Integrative Physiological and Behavioral Science [Internet]. 2003;38(2):133–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0141503153&doi=10.1007%252fbf02688831&partnerID=40&md5=f3bf9638791e2dd13a823ef64258d8ea

213.

Parker LA, Mechoulam R, Schlievert C, Abbott L, Fudge ML, Burton P. Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea. Psychopharmacology [Internet]. 2003;166(2):156–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037337169&doi=10.1007%252fs00213-002-1329-2&partnerID=40&md5=42ec0c12832e37ce601333d5fcb3c22e

214.

Mechoulam R, Hanuš L. Cannabidiol: An overview of some chemical and pharmacological aspects. Part I: Chemical aspects. Chemistry and Physics of Lipids [Internet]. 2002;121(1–2):35–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037207079&doi=10.1016%2fS0009-3084%2802%2900144-5&partnerID=40&md5=14ba5c904ca6388c4816bddc0e122389

215.

Laine K, Järvinen K, Mechoulam R, Breuer A, Järvinen T. Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid. Investigative Ophthalmology and Visual Science [Internet]. 2002;43(10):3216–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036784933&partnerID=40&md5=221e037cb4e54f539ac1fd2dd577856f

216.

Krylatov AV, Uzhachenko RV, Maslov LN, Bernatskaya NA, Makriyannis A, Mechoulam R, et al. Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: A possible mechanism. Bulletin of Experimental Biology and Medicine [Internet]. 2002;133(2):122–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036345306&doi=10.1023%252fA%253a1015574100494&partnerID=40&md5=483c716ad5d7c03015218e9c3464db83

217.

Ugdyzhekova DS, Krylatov AV, Bernatskaya NA, Maslov LN, Mechoulam R, Pertwee RG. Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis. Bulletin of Experimental Biology and Medicine [Internet]. 2002;133(2):125–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036342177&doi=10.1023%252fA%253a1015526217332&partnerID=40&md5=5a8ade9428ed4bdc9b09382b34e14983

218.

Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews [Internet]. 2002;54(2):161–202. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-18444376760&doi=10.1124%252fpr.54.2.161&partnerID=40&md5=77d8723946fc683fe082139ff64be04d

219.

Parker LA, Mechoulam R, Schlievert C. Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats. NeuroReport [Internet]. 2002;13(5):567–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037117750&doi=10.1097%252f00001756-200204160-00006&partnerID=40&md5=9f614ae6c7ab87258e7134aee0e89948

220.

Fezza F, Bisogno T, Minassi A, Appendino G, Mechoulam R, Di Marzo V. Noladin ether, a putative novel endocannabinoid: Inactivation mechanisms and a sensitive method for its quantification in rat tissues. FEBS Letters [Internet]. 2002;513(2–3):294–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037181180&doi=10.1016%2fS0014-5793%2802%2902341-4&partnerID=40&md5=8c8bed1032cb795c2d378ebde0c088c9

221.

Mechoulam R, Spatz M, Shohami E. Endocannabinoids and neuroprotection. Science’s STKE : signal transduction knowledge environment [Internet]. 2002;2002(129):RE5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037161476&doi=10.1126%252fstke.2002.129.re5&partnerID=40&md5=95d9639c38b13cee444c5e60c323e233

222.

Berry EM, Mechoulam R. Tetrahydrocannabinol and endocannabinoids in feeding and appetite. Pharmacology and Therapeutics [Internet]. 2002;95(2):185–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036669295&doi=10.1016%2fS0163-7258%2802%2900257-7&partnerID=40&md5=c34109f05d512ebbe20e3580db1e109a

223.

Krylatov AV, Bernatskaia NA, Maslov LN, Pertwee RG, Mechoulam R, Stefano GB, et al. Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors [Povyshenie ustoichivosti serdtsa k aritmogennym vozdeistviiam i umen’shenie zony ishemicheskogo nekroza miokarda pri aktivatsii kannabinoidnykh retseptorov.]. Rossiiskii fiziologicheskii zhurnal imeni IM Sechenova / Rossiiskaia akademiia nauk [Internet]. 2002;88(5):560–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036561668&partnerID=40&md5=572d7c16b9bdbe7e8bbee0fa104b4dd8

224.

Mechoulam R, Panikashvili D, Shohami E. Cannabinoids and brain injury: Therapeutic implications. Trends in Molecular Medicine [Internet]. 2002;8(2):58–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036156353&doi=10.1016%2fS1471-4914%2802%2902276-1&partnerID=40&md5=69f06fa881b51850ca991ed4a4bab005

225.

Mechoulam R. Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. Prostaglandins Leukotrienes and Essential Fatty Acids [Internet]. 2002;66(2–3):93–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036019381&doi=10.1054%252fplef.2001.0340&partnerID=40&md5=7d6de4c56b490a0e14c064a12bd46af0

226.

Panikashvili D, Simeonidou C, Ben-Shabat S, Hanuš L, Breuer A, Mechoulam R, et al. An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. Nature [Internet]. 2001;413(6855):527–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035807380&doi=10.1038%252f35097089&partnerID=40&md5=0413bea3242a71c89dc8fa6419bb8a4a

227.

Rubnov S, Kashman Y, Rabinowitz R, Schlesinger M, Mechoulam R. Suppressors of cancer cell proliferation from fig (Ficus carica) resin: Isolation and structure elucidation. Journal of Natural Products [Internet]. 2001;64(7):993–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034910124&doi=10.1021%252fnp000592z&partnerID=40&md5=1e1ed7d24728740464cdaa11051c00fd

228.

Fride E, Ginzburg Y, Breuer A, Bisogno T, Di Marzo V, Mechoulam R. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. European Journal of Pharmacology [Internet]. 2001;419(2–3):207–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035843790&doi=10.1016%2fS0014-2999%2801%2900953-0&partnerID=40&md5=da0e2b225315c99783dce9e007248c32

229.

Mechoulam R, Fride E. Physiology: A hunger for cannabinoids. Nature [Internet]. 2001;410(6830):763–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035848901&doi=10.1038%252f35071214&partnerID=40&md5=f83d25aedfb9c2c80b1309481c1060f5

230.

Hanus L, Abu-Lafi S, Fride E, Breuer A, Vogel Z, Shalev DE, et al. 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2001;98(7):3662–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035957425&doi=10.1073%252fpnas.061029898&partnerID=40&md5=4a755b7ea32ca42c31e63f925d21f540

231.

Crozier Willi G, Berger A, Di Marzo V, Bisogno T, De Petrocellis L, Fride E, et al. Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. Nestlé Nutrition workshop series Clinical & performance programme [Internet]. 2001;5:169–84; discussion 185-187. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035236042&doi=10.1159%252f000061850&partnerID=40&md5=12330e27124236415222b0a0457be8f0

232.

Mechoulam R, Hanuš L. The cannabinoids: An overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. Pain Research and Management [Internet]. 2001;6(2):67–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034891915&doi=10.1155%252f2001%252f183057&partnerID=40&md5=c6eea2f52a73f163df570d50df6989c3

233.

Bisogno T, Hanuš L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, et al. Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. British Journal of Pharmacology [Internet]. 2001;134(4):845–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034751335&doi=10.1038%252fsj.bjp.0704327&partnerID=40&md5=d2c988e068e9f72a74bc9763874f1df7

234.

Mechoulam R, Hanuš L. A historical overview of chemical research on cannabinoids. Chemistry and Physics of Lipids [Internet]. 2000;108(1–2):1–13. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033660254&doi=10.1016%2fS0009-3084%2800%2900184-5&partnerID=40&md5=fb9046772aff8fc6c2c846b7f2b3463c

235.

Tchilibon S, Mechoulam R. Synthesis of a primary metabolite of cannabidiol. Organic Letters [Internet]. 2000;2(21):3301–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034687196&doi=10.1021%252fol006369a&partnerID=40&md5=1e21dfcc9914828f99f9d13b9919b752

236.

Gallily R, Breuer A, Mechoulam R. 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-α production in murine macrophages, and in mice. European Journal of Pharmacology [Internet]. 2000;406(1):R5–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034613209&doi=10.1016%2fS0014-2999%2800%2900653-1&partnerID=40&md5=f0eb1cc0d0e5edf4ee46809c7d5aac68

237.

Chen Y, McCarron RM, Ohara Y, Bembry J, Azzam N, Lenz FA, et al. Human brain capillary endothelium: 2-Arachidonoglycerol (endocannabinoid) interacts with endothelin-1. Circulation Research [Internet]. 2000;87(4):323–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034682990&doi=10.1161%252f01.RES.87.4.323&partnerID=40&md5=a12a8e4806ff75c6c40e69b9415381b5

238.

Malfait AM, Gallily R, Sumariwalla PF, Malik AS, Andreakos E, Mechoulam R, et al. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2000;97(17):9561–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034662868&doi=10.1073%252fpnas.160105897&partnerID=40&md5=3f19e0747cdaf7a78ea5fa7823c3f040

239.

Hao S, Avraham Y, Mechoulam R, Berry EM. Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. European Journal of Pharmacology [Internet]. 2000;392(3):147–56. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034737597&doi=10.1016%2fS0014-2999%2800%2900059-5&partnerID=40&md5=f5d2a5e86828c24eddcc98baa23f7e12

240.

Ugdyzhekova DS, Davydova YG, Maimeskulova LA, Mechoulam R. Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine. Bulletin of Experimental Biology and Medicine [Internet]. 2000;130(11):1087–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035030755&doi=10.1023%252fA%253a1002899818918&partnerID=40&md5=20ebda2083f84b70ee3ceac9a44f39af

241.

Naveh N, Weissman C, Muchtar S, Benita S, Mechoulam R. A submicron emulsion of HU-211, a synthetic cannabinoid, reduces intraocular pressure in rabbits. Graefe’s Archive for Clinical and Experimental Ophthalmology [Internet]. 2000;238(4):334–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034018676&doi=10.1007%252fs004170050361&partnerID=40&md5=156f3cc88f9212f1e8e2c2603b506815

242.

Mechoulam R. Looking back at cannabis research. Current Pharmaceutical Design [Internet]. 2000;6(13):1313–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033847789&doi=10.2174%252f1381612003399509&partnerID=40&md5=01baaa8ff96e250e61c06712626e3a0e

243.

Shohami E, Mechoulam R. Dexanabinol (HU-211): A nonpsychotropic cannabinoid with neuroprotective properties. Drug Development Research [Internet]. 2000;50(3–4):211–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033819840&doi=10.1002%2f1098-2299%28200007%2f08%2950%3a3%2f4%3c211%3a%3aAID-DDR3%3e3.0.CO%3b2-G&partnerID=40&md5=91cd7c895a6de3756c7ba93e35765f57

244.

Mechoulam R. Recent advances in Cannabinoid research [Jungste fortschritte in der Cannabinoid-forschung]. Forschende Komplementarmedizin [Internet]. 1999;6(SUPPL. 3):16–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032742328&partnerID=40&md5=a36a6e8a006defd22e0cd8c899848e6a

245.

Hanuš L, Breuer A, Tchilibon S, Shiloah S, Goldenberg D, Horowitz M, et al. HU-308: A specific agonist for CB2, a peripheral cannabinoid receptor. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1999;96(25):14228–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-12944263838&doi=10.1073%252fpnas.96.25.14228&partnerID=40&md5=135fbe31b62f1b87d7278970c9a42e92

246.

Martin BR, Mechoulam R, Razdan RK. Discovery and characterization of endogenous cannabinoids. Life Sciences [Internet]. 1999;65(6–7):573–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033538561&doi=10.1016%2fS0024-3205%2899%2900281-7&partnerID=40&md5=f44288d64e611b549508954cc9d4d4f9

247.

Mechoulam R, Ben-Shabat S. From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: The ongoing story of cannabis. Natural Product Reports [Internet]. 1999;16(2):131–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033118863&doi=10.1039%252fa703973e&partnerID=40&md5=8d03263a37f4afa10c88731ff0d84aa9

248.

Ginsburg I, Sadovnik M, Sallon S, Milo-Goldzweig I, Mechoulam R, Breuer A, et al. PADMA-28, a traditional Tibetan herbal preparation inhibits the respiratory burst in human neutrophils, the killing of epithelial cells by mixtures of oxidants and pro-inflammatory agonists and peroxidation of lipids. Inflammopharmacology [Internet]. 1999;7(1):47–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033030005&doi=10.1007%252fs10787-999-0025-9&partnerID=40&md5=039924a5b6f5f1fa77933324a80596ba

249.

Mathews WB, Ravert HT, Scheffel U, Finley PA, Mechoulam R, Frost JJ, et al. Synthesis of [11C] HU-304*: A new radioligand for positron emission tomographic studies of cannabinoid receptors. Journal of Labelled Compounds and Radiopharmaceuticals [Internet]. 1999;42(SUPPL. 1):S467–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032789324&partnerID=40&md5=b0c93cb7e3fff464d7e1c5bab538145d

250.

Di Marzo V, Sepe N, De Petrocellis L, Berger A, Crozier G, Fride E, et al. Trick or treat from food endocannabinoids? [4] (multiple letters). Nature [Internet]. 1998;396(6712):636–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032542291&doi=10.1038%252f25270&partnerID=40&md5=556349c01128090b61849a8ebec052ca

251.

Mechoulam R, Fride E, Ben-Shabat S, Meiri U, Horowitz M. Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid. European Journal of Pharmacology [Internet]. 1998;362(1):R1–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032407065&doi=10.1016%2fS0014-2999%2898%2900777-8&partnerID=40&md5=bd5e38c77a71cb3cc260e28219e404f3

252.

Mechoulam R, Fride E, Di Marzo V. Endocannabinoids. European Journal of Pharmacology [Internet]. 1998;359(1):1–18. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032538527&doi=10.1016%2fS0014-2999%2898%2900649-9&partnerID=40&md5=26ba783fe320713653466e86378ff18a

253.

Ben-Shabat S, Fride E, Sheskin T, Tamiri T, Rhee MH, Vogel Z, et al. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. European Journal of Pharmacology [Internet]. 1998;353(1):23–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031830516&doi=10.1016%2fS0014-2999%2898%2900392-6&partnerID=40&md5=8f7c268667902bef74b53bef5adb3cfb

254.

Sulcova E, Mechoulam R, Fride E. Biphasic effects of anandamide. Pharmacology Biochemistry and Behavior [Internet]. 1998;59(2):347–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032005722&doi=10.1016%2fS0091-3057%2897%2900422-X&partnerID=40&md5=4fa4c191b803b52dc24279df35fab846

255.

Mechoulam R, Golan D. Comment on ‘Health aspects of cannabis: Revisited’ (Hollister). International Journal of Neuropsychopharmacology [Internet]. 1998;1(1):83–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018624595&doi=10.1017%252fS1461145798001126&partnerID=40&md5=e61f9cb2deafd78871d231aeee09c2e2

256.

Mechoulam R, Hanuš L, Fride E. 5 Towards cannabinoid drugs - revisited. Progress in Medicinal Chemistry [Internet]. 1998;35(C):199–243. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032227435&doi=10.1016%2fS0079-6468%2808%2970037-7&partnerID=40&md5=7cbc035a11b575df745e3ac84132a5da

257.

Gallily R, Yamin A, Waksmann Y, Ovadia H, Weidenfeld J, Bar-Joseph A, et al. Protection against septic shock and suppression of tumor necrosis factor α and nitric oxide production by dexanabinol (HU-211), a nonpsychotropic cannabinoid. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1997;283(2):918–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030730585&partnerID=40&md5=76e49a3afc1f4b959b1a1cbd81fcdc7b

258.

Bisogno T, Sepe N, De Petrocellis L, Mechoulam R, Di Marzo V. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. Biochemical and Biophysical Research Communications [Internet]. 1997;239(2):473–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031581072&doi=10.1006%252fbbrc.1997.7431&partnerID=40&md5=abf74a3a391a4efab02c5e58aa9d808a

259.

Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanuš L, et al. Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase. Journal of Medicinal Chemistry [Internet]. 1997;40(20):3228–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030756533&doi=10.1021%252fjm970126f&partnerID=40&md5=27c3d161b40478b592038c67785aae3c

260.

Sheskin T, Hanuš L, Slager J, Vogel Z, Mechoulam R. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. Journal of Medicinal Chemistry [Internet]. 1997;40(5):659–67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031051583&doi=10.1021%252fjm960752x&partnerID=40&md5=d616d92f91f5b7f60502c746393e3d24

261.

Shohami E, Gallily R, Mechoulam R, Bass R, Ben-Hur T. Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant. Journal of Neuroimmunology [Internet]. 1997;72(2):169–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031047431&doi=10.1016%2fS0165-5728%2896%2900181-6&partnerID=40&md5=85e7079949b9d33cb3c10d4558749d1b

262.

Mechoulam R. Todd’s achievement [6]. Nature [Internet]. 1997;386(6627):755. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030964104&doi=10.1038%252f386755c0&partnerID=40&md5=913275bcd447d1687d5231ca6db7f468

263.

Mechoulam R, Fride E, Hanuš L, Sheskin T, Bisogno T, Marzo VD, et al. Anandamide may mediate sleep induction [6]. Nature [Internet]. 1997;389(6646):25–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030885267&doi=10.1038%252f37891&partnerID=40&md5=98715464e5b08e91c25b6bd236f1c204

264.

Shohami E, Weidenfeld J, Ovadia H, Vogel Z, Hanuš L, Fride E, et al. Endogenous and synthetic cannabinoids: Recent advances. CNS Drug Reviews [Internet]. 1996;2(4):429–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-12644253801&doi=10.1111%252fj.1527-3458.1996.tb00310.x&partnerID=40&md5=dac662fc953e17399f5223daddbb5a9e

265.

Fride E, Mechoulam R. Ontogenetic development of the response to anandamide and Δ9-tetrahydrocannabinol in mice. Developmental Brain Research [Internet]. 1996;95(1):131–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030595002&doi=10.1016%2f0165-3806%2896%2900087-9&partnerID=40&md5=4e2dbf81c9cee048e9c2c56ff2a4fbb3

266.

Bayewitch M, Rhee MH, Avidor-Reiss T, Breuer A, Mechoulam R, Vogel Z. (-)-Δ9-Tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase. Journal of Biological Chemistry [Internet]. 1996;271(17):9902–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029664402&doi=10.1074%252fjbc.271.17.9902&partnerID=40&md5=698f486406a299250fd93bfc3e898e77

267.

Pop E, Soti F, Brewster ME, Barenholz Y, Korablyov V, Mechoulam R, et al. Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary heterocyclic nitrogen with increased water-solubility. Pharmaceutical Research [Internet]. 1996;13(3):469–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029880941&doi=10.1023%252fA%253a1016017331353&partnerID=40&md5=415e76e3db52717987c6529526e9bf60

268.

Pop E, Liu ZZ, Brewster ME, Barenholz Y, Korablyov V, Mechoulam R, et al. Derivatives of dexanabinol. I. Water-soluble salts of glycinate esters. Pharmaceutical Research [Internet]. 1996;13(1):62–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029868614&doi=10.1023%252fA%253a1016025216390&partnerID=40&md5=2bf907ec18e794a04f4898c1a2ab1956

269.

Mechoulam R, Ben Shabat S, Hanuš L, Fride E, Bayewitch M, Vogel Z. Endogenous cannabinoid ligands. Advances in Experimental Medicine and Biology [Internet]. 1996;402:95–100. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-10144253122&doi=10.1007%252f978-1-4613-0407-4_14&partnerID=40&md5=a4615d5fb6e65e79a64f59ca46e759da

270.

Mechoulam R, Ben Shabat S, Hanuš L, Fride E, Vogel Z, Bayewitch M, et al. Endogenous cannabinoid ligands - Chemical and biological studies. Journal of Lipid Mediators and Cell Signalling [Internet]. 1996;14(1–3):45–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030248907&doi=10.1016%2f0929-7855%2896%2901507-6&partnerID=40&md5=996595ba0a9d4e5fc7486888fc1d1196

271.

Wilson Jr. RG, Tahir SK, Mechoulam R, Zimmerman S, Zimmerman AM. Cannabinoid enantiomer action on the cytoarchitecture. Cell Biology International [Internet]. 1996;20(2):147–57. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029927507&doi=10.1006%252fcbir.1996.0019&partnerID=40&md5=ee34ed981eda8489b13334c73801413f

272.

Fride E, Mechoulam R. Developmental aspects of anandamide: Ontogeny of response and prenatal exposure. Psychoneuroendocrinology [Internet]. 1996;21(2):157–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029890308&doi=10.1016%2f0306-4530%2895%2900039-9&partnerID=40&md5=a5ae1587fb3e4416f5821a469e65daaa

273.

Barg J, Fride E, Hanus L, Levy R, Matus-Leibovitch N, Heldman E, et al. Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. European Journal of Pharmacology [Internet]. 1995;287(2):145–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028787448&doi=10.1016%2f0014-2999%2895%2900487-4&partnerID=40&md5=c584e65e4c5e15d845dcdc5c77231001

274.

Bayewitch M, Avidor-Reiss T, Levy R, Barg J, Mechoulam R, Vogel Z. The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling. FEBS Letters [Internet]. 1995;375(1–2):143–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028789427&doi=10.1016%2f0014-5793%2895%2901207-U&partnerID=40&md5=9a42ee58a03006f69bae1afdbd2b5a99

275.

Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochemical Pharmacology [Internet]. 1995;50(1):83–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029012014&doi=10.1016%2f0006-2952%2895%2900109-D&partnerID=40&md5=8c5cc503bac9f697fbb94bee8da104b8

276.

Abrahamov A, Abrahamov A, Mechoulam R. An efficient new cannabinoid antiemetic in pediatric oncology. Life Sciences [Internet]. 1995;56(23–24):2097–102. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029031524&doi=10.1016%2f0024-3205%2895%2900194-B&partnerID=40&md5=44892a4275e6cf735d3c8c656290b10f

277.

Ovadia H, Wohlman A, Mechoulam R, Weidenfeld J. Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens. Neuropharmacology [Internet]. 1995;34(2):1725–175. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029107835&partnerID=40&md5=9fa0d63fb9860679404fa301c06cb09b

278.

Ovadia H, Wohlman A, Mechoulam R, Weidenfeld J. Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens. Neuropharmacology [Internet]. 1995;34(2):175–80. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028915458&doi=10.1016%2f0028-3908%2894%2900133-D&partnerID=40&md5=eddb974a89293a9a411ba887445b8b66

279.

Taura F, Morimoto S, Shoyama Y, Mechoulam R. First Direct Evidence for the Mechanism of Δ1-Tetrahydrocannabinolie Acid Biosynthesis. Journal of the American Chemical Society [Internet]. 1995;117(38):9766–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028886934&doi=10.1021%252fja00143a024&partnerID=40&md5=654ded99dbd69570f40e0f3f5206bc54

280.

Zuardi AW, Morais SL, Guimaraes FS, Mechoulam R. Antipsychotic effect of cannabidiol [3]. Journal of Clinical Psychiatry [Internet]. 1995;56(10):485–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028881791&partnerID=40&md5=939e53494a5af73a635ab73e2b158a1f

281.

Fride E, Barg J, Levy R, Saya D, Heldman E, Mechoulam R, et al. Low doses of anandamides inhibit pharmacological effects of Δ9- tetrahydrocannabinol. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1995;272(2):699–707. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028872268&partnerID=40&md5=fc2ef29e1497a1f98fc162d37c1a7d9f

282.

Glaser R, Adin I, Mechoulam R, Hanuš L. 2-Methyl- and 4-methyl-δ8-tetrahydrocannabinol: Correlation of spatial distinction with cannabinoid receptor binding. Heterocycles [Internet]. 1994;39(2):867–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001514541&doi=10.3987%2fCOM-94-S%28B%2986&partnerID=40&md5=ea6d521907b3880545a343022773bd3d

283.

Martin BR, Childers S, Howlett A, Mechoulam R, Pertwee R. Cannabinoid receptors: Pharmacology, second messenger systems and endogenous ligands. NIDA Research Monograph Series [Internet]. 1994;(140):55–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028679794&partnerID=40&md5=dece021eca65fe3e3a375870cbfe998e

284.

Vogel Z, Bayewitch M, Levy R, Matus-Leibovitch N, Hanus L, Ben-Shabat S, et al. Binding and functional studies with the peripheral and neuronal cannabinoid receptors. Regulatory Peptides [Internet]. 1994;54(1):313–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028110307&doi=10.1016%2f0167-0115%2894%2990515-0&partnerID=40&md5=c3e781b8ea382e12beb152b4b0071a35

285.

Mechoulam R, Hanuš L, Martin BR. Search for endogenous ligands of the cannabinoid receptor. Biochemical Pharmacology [Internet]. 1994;48(8):1537–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028032515&doi=10.1016%2f0006-2952%2894%2990197-X&partnerID=40&md5=784d9bd7e0966028acdf7e4384875b27

286.

Schuel H, Goldstein E, Mechoulam R, Zimmerman AM, Zimmerman S. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1994;91(16):7678–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027982533&doi=10.1073%252fpnas.91.16.7678&partnerID=40&md5=b989b1342ca6e463c05fdd2b5d34be53

287.

Pertwee R, Griffin G, Hanuš L, Mechoulam R. Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia. European Journal of Pharmacology [Internet]. 1994;259(2):115–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028226120&doi=10.1016%2f0014-2999%2894%2990499-5&partnerID=40&md5=581dee0e08652906bc3b2d151792fa47

288.

Abu-Lafi S, Sterin M, Levin S, Mechoulam R. Structural features affecting chiral discrimination of terpene derivatives, on a carbamated amylose stationary phase. Journal of Chromatography A [Internet]. 1994;664(2):159–67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028326234&doi=10.1016%2f0021-9673%2894%2987003-9&partnerID=40&md5=6f4b3bc04f744a2b064bc2b34bd1a6bd

289.

Rodríguez De Fonseca F, Martín Calderón JL, Mechoulam R, Navarro M. Repeated stimulation of D1 dopamine receptors enhances (-)-11-hydroxy-Δ8-tetrahydrocannabinol-dimethylheptyl-induced catalepsy in male rats. NeuroReport [Internet]. 1994;5(7):761–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028777964&doi=10.1097%252f00001756-199403000-00006&partnerID=40&md5=16ba7994eabb2ae59a5752c07334779e

290.

Mechoulam R. Cannabis chemistry, biochemistry, toxicology and therapeutic applications. Japanese Journal of Forensic Toxicology [Internet]. 1994;12(2):76–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028319239&partnerID=40&md5=d38616795400ccc8b90ffb79eaed2aa9

291.

Smith PB, Compton DR, Welch SP, Razdan RK, Mechoulam R, Martin BR. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1994;270(1):219–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028291118&partnerID=40&md5=d9ecfd7bef4dde709b8ba7c81b1ef457

292.

Weidenfeld J, Feldman S, Mechoulam R. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. Neuroendocrinology [Internet]. 1994;59(2):110–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028120958&doi=10.1159%252f000126646&partnerID=40&md5=fd548bbb1706084811b75218269ebe64

293.

Guimarães FS, Aguiar JC d., Mechoulam R, Breuer A. Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze. General Pharmacology [Internet]. 1994;25(1):161–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028089295&doi=10.1016%2f0306-3623%2894%2990027-2&partnerID=40&md5=b18b660535c2eca123b232b99483c37e

294.

Wirguin I, Mechoulam R, Breuer A, Schezen E, Weidenfeld J, Brenner T. Suppression of experimetal autoimmune encephalomyelitis by cannabinoids. Immunopharmacology [Internet]. 1994;28(3):209–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028080884&doi=10.1016%2f0162-3109%2894%2990056-6&partnerID=40&md5=a18e6587b3ae13a9c870dc684e436ddf

295.

Järbe TUC, Mechoulam R, Zahalka J. Discriminative stimulus- and open-field effects of the enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol in pigeons and gerbils. Pharmacology, Biochemistry and Behavior [Internet]. 1994;47(1):113–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027953165&doi=10.1016%2f0091-3057%2894%2990119-8&partnerID=40&md5=8658a5112ce0ff517d0f8756c2fd04c4

296.

Mechoulam R, Vogel Z, Barg J. CNS Cannabinoid Receptors: Role and Therapeutic Implications for CNS Disorders. CNS Drugs [Internet]. 1994;2(4):255–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000507883&doi=10.2165%252f00023210-199402040-00001&partnerID=40&md5=cd4ab9340d77ce2fbacc1f0206f7fd2b

297.

Jarbe TUC, Hiltunen AJ, Mathis DA, Hanus L, Breuer A, Mechoulam R. Discriminative stimulus effects and receptor binding of enantiomeric pairs of cannabinoids in rats and pigeons; A comparison. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1993;264(2):561–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027749691&partnerID=40&md5=11ac13a41300e6d87505bae97621e04c

298.

Levin S, Abu-Lafi S, Zahalka J, Mechoulam R. Resolution of chiral cannabinoids on amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase: Effects of structural features and mobile phase additives. Journal of Chromatography A [Internet]. 1993;654(1):53–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027432964&doi=10.1016%2f0021-9673%2893%2983064-Y&partnerID=40&md5=420edda2dd9152309da997a7871a3033

299.

Nadler V, Mechoulam R, Sokolovsky M. The non-psychotropic cannabinoid (+)-(3S,4S)-7-hydroxy-Δ6-tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates N-methyl-d-aspartate receptor-mediated neurotoxicity in primary cultures of rat forebrain. Neuroscience Letters [Internet]. 1993;162(1–2):43–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027381303&doi=10.1016%2f0304-3940%2893%2990555-Y&partnerID=40&md5=9a16745ba8899e4edc7ff74911a9e611

300.

Nadler V, Mechoulam R, Sokolovsky M. Blockade of 45Ca2+ influx through the N-methyl-d-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211. Brain Research [Internet]. 1993;622(1–2):79–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027329873&doi=10.1016%2f0006-8993%2893%2990804-V&partnerID=40&md5=40c9d1854721763dd6c6ca8997b61af6

301.

Fride E, Mechoulam R. Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent. European Journal of Pharmacology [Internet]. 1993;231(2):313–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027467421&doi=10.1016%2f0014-2999%2893%2990468-W&partnerID=40&md5=58452de2c63920f77d732926dc30a796

302.

Martin BR, Cabral G, Childers SR, Deadwyler S, Mechoulam R, Reggio P. International Cannabis Research Society Meeting Summary, Keystone, CO (June 19-20, 1992). Drug and Alcohol Dependence [Internet]. 1993;31(3):219–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027497894&doi=10.1016%2f0376-8716%2893%2990004-A&partnerID=40&md5=51a843fa0fb6f82b68f30115f484b105

303.

Hanuš L, Gopher A, Almog S, Mechoulam R. Two New Unsaturated Fatty Acid Ethanolamides in Brain That Bind to the Cannabinoid Receptor. Journal of Medicinal Chemistry [Internet]. 1993;36(20):3032–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027489995&doi=10.1021%252fjm00072a026&partnerID=40&md5=288086b792aed6454c8484000093e549

304.

Vogel Z, Barg J, Levy R, Saya D, Heldman E, Mechoulam R. Anandamide, a Brain Endogenous Compound, Interacts Specifically with Cannabinoid Receptors and Inhibits Adenylate Cyclase. Journal of Neurochemistry [Internet]. 1993;61(1):352–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027315816&doi=10.1111%252fj.1471-4159.1993.tb03576.x&partnerID=40&md5=6be8ee747eeed31e5caf0cdd6a40e632

305.

Shohami E, Novikov M, Mechoulam R. A Nonpsychotropic Cannabinoid, HU-211, Has Cerebroprotective Effects After Closed Head Injury in the Rat. Journal of Neurotrauma [Internet]. 1993;10(2):109–19. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027250138&doi=10.1089%252fneu.1993.10.109&partnerID=40&md5=a3228856b7d6be20f32a4431c42b0278

306.

Zlas J, Stark H, Seligman J, Levy R, Werker E, Breuer A, et al. Early medical use of cannabis [5]. Nature [Internet]. 1993;363(6426):215. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027231337&doi=10.1038%252f363215a0&partnerID=40&md5=6acc634c9b5de67a91c36c6cd1364789

307.

Burstein SH, Audette CA, Doyle SA, Breuer A, Devane WA, Colodner S, et al. Synthetic Nonpsychotropic Cannabinoids with Potent Antiinflammatory, Analgesic, and Leukocyte Antiadhesion Activities. Journal of Medicinal Chemistry [Internet]. 1992;35(17):3135–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026671288&doi=10.1021%252fjm00095a007&partnerID=40&md5=4981023af85eec414a10074209dbe0dd

308.

Devane WA, Breuer A, Sheskin T, Järbe TUC, Eisen MS, Mechoulam R, et al. A Novel Probe for the Cannabinoid Receptor. Journal of Medicinal Chemistry [Internet]. 1992;35(11):2065–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026715999&doi=10.1021%252fjm00089a018&partnerID=40&md5=db49a2b6d2bab81f3bd0ea7731454a74

309.

Devane WA, Hanuš L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science [Internet]. 1992;258(5090):1946–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027078685&doi=10.1126%252fscience.1470919&partnerID=40&md5=dc9c5517bc0458f9fa1d18dd6fd09b57

310.

Nathan I, Agam G, Mechoulam R, Dvilansky A, Livne AA. Effect of synthetic enantiomeric cannabinoids on platelet aggregation. Canadian Journal of Physiology and Pharmacology [Internet]. 1992;70(10):1305–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027078319&doi=10.1139%252fy92-182&partnerID=40&md5=614a4ec0e77a4554d7b7f2ba6fb8ed51

311.

Pertwee RG, Stevenson LA, Elrick DB, Mechoulam R, Corbett AD. Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea‐pig small intestine. British Journal of Pharmacology [Internet]. 1992;105(4):980–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026560734&doi=10.1111%252fj.1476-5381.1992.tb09088.x&partnerID=40&md5=263828ec37975775b327ce0f46f2ed14

312.

Harvey DJ, Samara E, Mechoulam R. Urinary metabolites of cannabidiol in dog, rat and man and their identification by gas chromatography-mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications [Internet]. 1991;562(1–2):299–322. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026087928&doi=10.1016%2f0378-4347%2891%2980587-3&partnerID=40&md5=f30d539750a68a604bdb4b1e38affbea

313.

Mechoulam R, Breuer A, Feigenbaum JJ, Devane WA. Nonpsychotropic synthetic cannabinoids as therapeutic agents. Farmaco [Internet]. 1991;46(SUPPL. 1):267–76. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026019269&partnerID=40&md5=a6009cc902981dcbd26e97de896e52d0

314.

Zimmerman AM, Titishov N, Mechoulam R, Zimmerman S. Effect of stereospecific cannabinoids on the immune system. Advances in Experimental Medicine and Biology [Internet]. 1991;288:71–80. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025995445&doi=10.1007%252f978-1-4684-5925-8_8&partnerID=40&md5=22b0306d20b8a96bd39abf25305457e5

315.

Zeltser R, Seltzer Z, Eisen A, Feigenbaum JJ, Mechoulam R. Suppression of neuropathic pain behavior in rats by a non-psychotropic synthetic cannabinoid with NMDA receptor-blocking properties. Pain [Internet]. 1991;47(1):95–103. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025948539&doi=10.1016%2f0304-3959%2891%2990016-Q&partnerID=40&md5=bdef6eab2067c20abb851e32a7ce5cce

316.

Mechoulam R, Devane WA, Breuer A, Zahalka J. A random walk through a cannabis field. Pharmacology, Biochemistry and Behavior [Internet]. 1991;40(3):461–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025841782&doi=10.1016%2f0091-3057%2891%2990347-5&partnerID=40&md5=20f48c91a75b341bef1ca401370d85b2

317.

Harvey DJ, Samara E, Mechoulam R. Comparative metabolism of cannabidiol in dog, rat and man. Pharmacology, Biochemistry and Behavior [Internet]. 1991;40(3):523–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025787997&doi=10.1016%2f0091-3057%2891%2990358-9&partnerID=40&md5=73225a8ffee57e56c2fbd18fd3ceaf7c

318.

Martin BR, Compton DR, Thomas BF, Prescott WR, Little PJ, Razdan RK, et al. Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs. Pharmacology, Biochemistry and Behavior [Internet]. 1991;40(3):471–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025787612&doi=10.1016%2f0091-3057%2891%2990349-7&partnerID=40&md5=739f5e930254456d6d24fde4f98af908

319.

Harvey DJ, Mechoulam R. Metabolites of cannabidiol identified in human urine. Xenobiotica [Internet]. 1990;20(3):303–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025257037&doi=10.3109%252f00498259009046849&partnerID=40&md5=784ddc289623a5f1b3c8d1dae26add63

320.

Mechoulam R, Breuer A, Järbe TUC, Hiltunen AJ, Glaser R. Cannabimimetic Activity of Novel Enantiomeric, Benzofuran Cannabinoids. Journal of Medicinal Chemistry [Internet]. 1990;33(3):1037–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025218666&doi=10.1021%252fjm00165a024&partnerID=40&md5=183c9d869df4b45922121ba28f63024f

321.

Howlett AC, Champion TM, Wilken GH, Mechoulam R. Stereochemical effects of 11-OH-Δ8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor. Neuropharmacology [Internet]. 1990;29(2):161–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025186592&doi=10.1016%2f0028-3908%2890%2990056-W&partnerID=40&md5=f99f8363d84a548899799ce76eddc106

322.

Mechoulam R, Lander N, University A, Zahalka J. Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative. Tetrahedron: Asymmetry [Internet]. 1990;1(5):315–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024986448&doi=10.1016%2fS0957-4166%2800%2986322-3&partnerID=40&md5=89cd7b31985bbf536f59b13b139fcf18

323.

Feigenbaum JJ, Bergmann F, Richmond SA, Mechoulam R, Nadler V, Kloog Y, et al. Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1989;86(23):9584–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024316874&doi=10.1073%252fpnas.86.23.9584&partnerID=40&md5=9274d251c377c4e6a6a2b7a567b4e29d

324.

Feigenbaum JJ, Richmond SA, Weissman Y, Mechoulam R. Inhibition of cisplatin-induced emesis in the pigeon by a non-psychotropic synthetic cannabinoid. European Journal of Pharmacology [Internet]. 1989;169(1):159–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024359059&doi=10.1016%2f0014-2999%2889%2990828-5&partnerID=40&md5=b8d47a284d5ef58a453681ea8bd914fc

325.

Mechoulam R. Alkaloids in Cannabis Sativa L. Alkaloids: Chemistry and Pharmacology [Internet]. 1989;34(C):77–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957051432&doi=10.1016%2fS0099-9598%2808%2960227-8&partnerID=40&md5=26886932730f2f88fb8cf96759e3097e

326.

Titishov N, Mechoulam R, Zimmerman AM. Stereospecific effects of (-)- and (+)-7-hydroxy-delta-6-tetrahydrocannabinol-dimethylheptyi on the immune system of mice. Pharmacology [Internet]. 1989;39(6):337–49. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024805923&doi=10.1159%252f000138621&partnerID=40&md5=25b7fbb2eba897b42a0da13e58e2de53

327.

Jarbe TUC, Hiltunen AJ, Mechoulam R. Stereospecificity of the discriminative stimulus functions of the dimethylheptyl homologs of 11-hydroxy-Δ8-tetrahydrocannabinol in rats and pigeons. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1989;250(3):1000–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024441853&partnerID=40&md5=1e68c401064f5315ecfe4a7dae373956

328.

Little PJ, Compton DR, Mechoulam R, Martin BR. Stereochemical effects of 11-OH-Δ8-THC-dimethylheptyl in mice and dogs. Pharmacology, Biochemistry and Behavior [Internet]. 1989;32(3):661–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024377764&doi=10.1016%2f0091-3057%2889%2990014-2&partnerID=40&md5=6266aef5a2813de36dd438e84a3cf09d

329.

Järbe TUC, Hiltunen AJ, Mechoulam R. Subjectively experienced cannabis effects in animals. Drug Development Research [Internet]. 1989;16(2–4):385–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024348222&doi=10.1002%252fddr.430160232&partnerID=40&md5=fa446045f7e447a62c09693c57f54df9

330.

Järbe TUC, Hiltunen AJ, Mechoulam R, Srebnik M, Breuer A. Separation of the discriminative stimulus effects of stereoisomers of Δ2- and Δ3-tetrahydrocannabinols in pigeons. European Journal of Pharmacology [Internet]. 1988;156(3):361–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023697956&doi=10.1016%2f0014-2999%2888%2990281-6&partnerID=40&md5=94a94d72b7997eef401254503658ae6e

331.

Mechoulam R, Feigenbaum JJ, Lander N, Segal M, Järbe TUC, Hiltunen AJ, et al. Enantiomeric cannabinoids: stereospecificity of psychotropic activity. Experientia [Internet]. 1988;44(9):762–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023791260&doi=10.1007%252fBF01959156&partnerID=40&md5=70bd7dfa07fe1f7e1fdcbbbd8e52ae0d

332.

Samara E, Bialer M, Mechoulam R. Pharmacokinetics of cannabidiol in dogs. Drug Metabolism and Disposition [Internet]. 1988;16(3):469–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023877617&partnerID=40&md5=ae2d69ba6f0fba456e47631603ffca16

333.

Hollister LE, Gillespie HK, Mechoulam R, Srebnik M. Human pharmacology of 1S and 1R enantiomers of delta-3-tetrahydrocannabinol. Psychopharmacology [Internet]. 1987;92(4):505–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023191071&doi=10.1007%252fBF00176485&partnerID=40&md5=bd1c086a05b079cc04f3c2f1d852cf90

334.

Yocum LB, Denlinger DL, Katlic NE, Brueggemeier RW, Mechoulam R. A developmental profile of estrogen and androgen radioimmunoactive substances in the flesh fly, Sarcophaga crassipalpis. Insect Biochemistry [Internet]. 1987;17(8):1149–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-38249038031&doi=10.1016%2f0020-1790%2887%2990087-4&partnerID=40&md5=7aacb6d44bdc7ca42287e029399d0208

335.

Srebnik M, Mechoulam R, Yona I. Halogenation of phenols and phenyl ethers with potassium halides in the presence of 18-crown-6 on oxidation with m-chloroperbenzoic acid. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1987;1423–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049075682&doi=10.1039%252fp19870001423&partnerID=40&md5=f4ce47402de70ca25a8b7325a9c23e75

336.

Mechoulam R, Feigenbaum JJ. Towards cannabinoid drugs. Progress in Medicinal Chemistry [Internet]. 1987;24(C):159–207. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023529144&doi=10.1016%2fS0079-6468%2808%2970422-3&partnerID=40&md5=75e6f184bb84135681bc8323fb59563e

337.

Martin AR, Consroe P, Kane VV, Shah V, Singh V, Lander N, et al. Structure-anticonvulsant activity relationships of cannabidiol analogs. NIDA research monograph [Internet]. 1987;79:48–58. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023505006&partnerID=40&md5=4210770596bb4756d490a84242dba87e

338.

Consroe P, Mechoulam R. Anticonvulsant and neurotoxic effects of tetrahydrocannabinol stereoisomers. NIDA research monograph [Internet]. 1987;79:59–66. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023496402&partnerID=40&md5=5c00036785745d2716c90553ec9d5c2b

339.

Mechoulam R, Lander N, Srebnik M, Breuer A, Segal M, Feigenbaum JJ, et al. Stereochemical requirements for cannabimimetic activity. NIDA research monograph [Internet]. 1987;79:15–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023464470&partnerID=40&md5=60bf30e84ce4206b0057b4e859070524

340.

Burstein S, Hunter SA, Latham V, Mechoulam R, Melchior DL, Renzulli L, et al. Prostaglandins and cannabis XV. Comparison of enantiomeric cannabinoids in stimulating prostaglandin synthesis in fibroblasts. Life Sciences [Internet]. 1986;39(19):1813–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022918325&doi=10.1016%2f0024-3205%2886%2990101-3&partnerID=40&md5=a576428aa7a4e5fe6a7c457ef00a09b1

341.

Mechoulam R. Interview with Prof. Raphael mechoulam, codiscoverer of THC. Substance Use and Misuse [Internet]. 1986;21(4–5):579–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907116118&doi=10.3109%252f10826088609083542&partnerID=40&md5=b483dcf04a2b80da1250206019ae116e

342.

Järbe TUC, Hiltunen AJ, Lander N, Mechoulam R. Cannabimimetic activity (Δ1-THC cue) of cannabidiol monomethyl ether and two stereoisomeric hexahydrocannabinols in rats and pigeons. Pharmacology, Biochemistry and Behavior [Internet]. 1986;25(2):393–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022473089&doi=10.1016%2f0091-3057%2886%2990015-8&partnerID=40&md5=e76edab8d058375347f82a6566a168ad

343.

Baek SH, Srebnik M, Mechoulam R. Boron triflouride etherate on alimina - a modified Lewis acid reagent. An improved synthesis of cannabidiol. Tetrahedron Letters [Internet]. 1985;26(8):1083–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000849287&doi=10.1016%2fS0040-4039%2800%2998518-6&partnerID=40&md5=bbb43e5367bb07e04f85116e6a119cb1

344.

Mechoulam R, Brueggemeier RW, Denlinger DL. Estrogens in insects. Experientia [Internet]. 1984;40(9):942–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021674993&doi=10.1007%252fBF01946450&partnerID=40&md5=6317a8a353769da46ab5587c9bcc506e

345.

Srebnik M, Mechoulam R. A new easy method for the synthesis of cyclic halogenoethers and halogenolactones. Journal of the Chemical Society, Chemical Communications [Internet]. 1984;(16):1070–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049107306&doi=10.1039%252fC39840001070&partnerID=40&md5=d1ac00801d0d5fb24866a0a30cafd762

346.

Srebnik M, Mechoulam R. Reactions of cannabinoid tosylhydrazones. Stereochemical aspects. Tetrahedron [Internet]. 1984;40(19):3839–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021723081&doi=10.1016%2fS0040-4020%2801%2988815-3&partnerID=40&md5=7be8a9b1776e64674e1cdbcc7e5d3833

347.

Edery H, Porath G, Mechoulam R, Lander N, Srebnik M, Lewis N. Activity of novel aminocannabinoids in baboons. Journal of Medicinal Chemistry [Internet]. 1984;27(10):1370–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021178519&doi=10.1021%252fjm00376a029&partnerID=40&md5=63b2ac13c74e9d30c0f6680b7ea2320b

348.

Srebnik M, Lander N, Breuer A, Mechoulam R. Base-catalysed double-bond isomerizations of cannabinoids: Structural and stereochemical aspects. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1984;2881–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0002477476&doi=10.1039%252fp19840002881&partnerID=40&md5=94360ef0ee1d0181bed602e20ea73c6e

349.

Gez E, Biran S, Fuks Z, Edelstein E, Lander N, Mechoulam R. A marihuana component for nausea and vomiting induced by chemo- and radiotherapy. Harefuah [Internet]. 1983;105(10):306-308+348. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021045250&partnerID=40&md5=3c9b8beb4ee891a5e5ef6d5b8699290d

350.

Mechoulam R, Lander N, Dikstein S, Shalita B. Cannabinoid drugs. Archives of Toxicology [Internet]. 1983;53(Suppl. 6):104. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020636543&partnerID=40&md5=d3dbebe08c84ad153eafed2f877b61f1

351.

Srebnik M, Mechoulam R. A facile method for regiospecific hydroxylation of resorcinol diethers. Synthesis (Germany) [Internet]. 1983;1983(12):1046–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0002440352&doi=10.1055%252fs-1983-30624&partnerID=40&md5=4c73c661ddb7bef1266da673a92ed51b

352.

Consroe P, Benedito MAC, Leite JR, Carlini EA, Mechoulam R. Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice. European Journal of Pharmacology [Internet]. 1982;83(3–4):293–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019929137&doi=10.1016%2f0014-2999%2882%2990264-3&partnerID=40&md5=bf603cc509c7b5944f02965b65a4e39d

353.

Leite JR, Carlini EA, Lander N, Mechoulam R. Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology [Internet]. 1982;24(3):141–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020077838&doi=10.1159%252f000137588&partnerID=40&md5=43c0bd5e6cece7875947b0d6f9e7365e

354.

Zehavi U, Mechoulam R. O- and C-d-glucosyluronic acid derivatives of Δ1-tetrahydrocannabinol: Synthesis and differential behavior to β-glucuronidase. Carbohydrate Research [Internet]. 1981;98(1):143–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019747728&doi=10.1016%2fS0008-6215%2800%2987152-9&partnerID=40&md5=0d89a1942041d6057759e35d92a46863

355.

Järbe TUC, Swedberg MDB, Mechoulam R. A repeated tests procedure to assess onset and duration of the cue properties of (-)Δ9-THC, (-)Δ8-THC-DMH and (+)Δ8-THC. Psychopharmacology [Internet]. 1981;75(2):152–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019732247&doi=10.1007%252fBF00432178&partnerID=40&md5=2e8d3433a2e0a21eae3df05d5713ea72

356.

Bialer M, El‐On J, Yagen B, Mechoulam R. Antiparasitic structure‐activity relationships of congocidine derivatives. Journal of Pharmaceutical Sciences [Internet]. 1981;70(7):822–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019870538&doi=10.1002%252fjps.2600700735&partnerID=40&md5=6fdcd884181863044c8e4f021fffa51e

357.

MECHOULAM R. Current Status of Therapeutic Opportunities Based on Cannabinoid Research. An Overview. The Journal of Clinical Pharmacology [Internet]. 1981;21(1 S):2S-7S. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019604853&doi=10.1002%252fj.1552-4604.1981.tb02567.x&partnerID=40&md5=799ad822711f5c9fb83b3caf81eccefb

358.

Noam M, Tamir I, Breuer E, Mechoulam R. Conversion of ruscogenin into 1α- and 1β hydroxycholesterol derivatives. Structure elucidation by computer assisted analysis of their lanthanide-induced nmr shifts. Tetrahedron [Internet]. 1981;37(3):597–604. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000931594&doi=10.1016%2fS0040-4020%2801%2992435-4&partnerID=40&md5=d362881fc2746241f939a8b90104ddcd

359.

Bialer M, Yagen B, Mechoulam R, Becker Y. Structure-Activity Relationships of Pyrrole Amidine Antiviral Antibiotics. 2. Preparation of Mono-and Tripyrrole Derivatives of Congocidine. Journal of Medicinal Chemistry [Internet]. 1980;23(10):1144–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019186958&doi=10.1021%252fjm00184a018&partnerID=40&md5=50a6baf231926438d179e64dafb0da9f

360.

Mechoulam R, Lander N, Varkony TH, Kimmel I, Becker O, Ben-Zvi Z, et al. Stereochemical Requirements for Cannabinoid Activity. Journal of Medicinal Chemistry [Internet]. 1980;23(10):1068–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019167502&doi=10.1021%252fjm00184a002&partnerID=40&md5=b6995290aec41df3f483d0e33d6e33cc

361.

Revuelta AV, Cheney DL, Costa E, Lander N, Mechoulam R. Reduction of hippocampal acetylcholine turnover in rats treated with (-)-Δ8-tetrahydrocannabinol and its 1′,2′-dimethyl-heptyl homolog. Brain Research [Internet]. 1980;195(2):445–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018820525&doi=10.1016%2f0006-8993%2880%2990078-5&partnerID=40&md5=0bbc49cc2a9af4f18ab53958d3e4f459

362.

Tamir I, Mechoulam R, Meyer AY. Cannabidiol and Phenytoin: A Structural Comparison. Journal of Medicinal Chemistry [Internet]. 1980;23(2):220–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018913023&doi=10.1021%252fjm00176a022&partnerID=40&md5=a2ca6f5e97f5b99d8acba3228fcfc8bb

363.

Mechoulam R, Lander N, Tamir I, Ben‐Zvi Z, Kimmel Y. Base‐Catalyzed Conversion of an Equatorial into an Axial Methoxycarbonyl Group Due to a 1,5‐Long‐Range Substituent Effect. Angewandte Chemie International Edition in English [Internet]. 1980;19(7):543–543. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84985569580&doi=10.1002%252fanie.198005431&partnerID=40&md5=616414090ab78298631b39dc8f03f2fb

364.

Bialer M, Yagen B, Mechoulam R, Becker Y. Structure–activity relationships of pyrrole amidine antiviral antibiotics III: Preparation of distamycin and congocidine derivatives based on 2,5‐disubstituted pyrroles. Journal of Pharmaceutical Sciences [Internet]. 1980;69(11):1334–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019257423&doi=10.1002%252fjps.2600691125&partnerID=40&md5=757afa306a2e971df0a91b6d3dc386ad

365.

Bialer M, Yagen B, Mechoulam R. Structure elucidation of a condensation product of 4‐aminopyrrole derivatives and dicyclohexylcarbodiimide. Journal of Heterocyclic Chemistry [Internet]. 1980;17(8):1797–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019176806&doi=10.1002%252fjhet.5570170834&partnerID=40&md5=0515ac0a128d1b1638a44a381e2fcb5a

366.

Mechoulam R, Lander N. Cannabis: a possible source of new drugs. Pharmacy International [Internet]. 1980;1(1):19–21. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019153544&partnerID=40&md5=af15326ee80dd971b32b2cc441726ea4

367.

Cunha JM, Carlini EA, Pereira AE, Ramos OL, Pimentel C, Gagliardi R, et al. Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Pharmacology [Internet]. 1980;21(3):175–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018947105&doi=10.1159%252f000137430&partnerID=40&md5=7b05447d2f3cd6955f76f348166e4723

368.

Cordova T, Ayalon D, Lander N, Mechoulam R, Nir I, Puder M, et al. The ovulation blocking effect of cannabinoids: Structure-activity relationships. Psychoneuroendocrinology [Internet]. 1980;5(1):53–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018905179&doi=10.1016%2f0306-4530%2880%2990009-8&partnerID=40&md5=922c7b4a2b723df6fc3454f5c928e88c

369.

Ohlsson A, Agurell S, Leander K, Dahmén J, Edery H, Porath G, et al. Synthesis and psychotropic activity of side-chain hydroxylated Δ 6-tetrahydrocannabinol metabolites. Acta Pharmaceutica Suecica [Internet]. 1979;16(1):21–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018764929&partnerID=40&md5=4325a5ad95425445b777ddf98ae22e61

370.

Agurell S, Edward C, Halldin M, Leander K, Levy S, Lindgren JE, et al. Chemical synthesis and biological occurrence of carboxylic acid metabolites of Δ1(6)-tetrahydrocannabinol. Drug Metabolism and Disposition [Internet]. 1979;7(3):155–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018375421&partnerID=40&md5=a07e9fce7366b6335c601efbbd859f35

371.

Bialer M, Yagen B, Mechoulam R, Becker Y. Structure-Activity Relationships of Pyrrole Amidine Antiviral Antibiotics. 1. Modifications of the Alkylamidine Side Chain. Journal of Medicinal Chemistry [Internet]. 1979;22(11):1296–301. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018639797&doi=10.1021%252fjm00197a004&partnerID=40&md5=f7fe40581342d6f580c49705d1bc1d4a

372.

Rosell S, Björkroth U, Agurell S, Leander K, Ohlsson A, Martin B, et al. Relation between effects of cannabinoid derivatives on the twitch response of the isolated guinea-pig ileum and their psychotropic properties. Advances in the biosciences [Internet]. 1978;22–23:63–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018274893&partnerID=40&md5=f3d188e402065c2c41a0f503ba5561e9

373.

Mechoulam R, Carlini EA. Toward drugs derived from cannabis. Naturwissenschaften [Internet]. 1978;65(4):174–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018150536&doi=10.1007%252fBF00450585&partnerID=40&md5=29d8b23d0ac42bcb4a1b6652032628aa

374.

Levy S, Yagen B, Mechoulam R. Identification of a C-glucuronide of δ6- tetrahydrocannabinol as a mouse liver conjugate in vivo. Science [Internet]. 1978;200(4348):1391–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018275382&doi=10.1126%252fscience.200.4348.1391&partnerID=40&md5=88d4d7f4fdca49719eb63bc66135965b

375.

Bialer M, Yagen B, Mechoulam R. A total synthesis of distamycin a, an antiviral antibiotic. Tetrahedron [Internet]. 1978;34(15):2389–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000515208&doi=10.1016%2f0040-4020%2878%2989056-5&partnerID=40&md5=8e0235715d559845cae2fb5e241204e2

376.

McCallum NK, Gugelmann A, Brenninkmeijer CAM, Mechoulam R. Isotope effect studies on the dehydrogenation of Δ1-tetrahydrocannabinol in the rat. Experientia [Internet]. 1977;33(8):1012–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017706227&doi=10.1007%252fBF01945939&partnerID=40&md5=d6deee80257921354ab751b5a9e760b4

377.

Goldblum A, Mechoulam R. Sodium chromate oxidation of enol benzoates. Allylic oxidation versus a novel rearrangement. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1977;1889–98. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84918615518&doi=10.1039%252fP19770001889&partnerID=40&md5=23d4e5a4cd7f29d6bd4ec31c5f0c89b2

378.

Yagen B, Levy S, Mechoulam R, Ben-Zvi Z. Synthesis and Enzymatic Formation of a C-Glucuronide of Δ6-Tetrahydrocannabino. Journal of the American Chemical Society [Internet]. 1977;99(19):6444–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017697103&doi=10.1021%252fja00461a048&partnerID=40&md5=76cd40bb27161747f14dff2e2baff94b

379.

Lander N, Mechoulam R. Formation of ortho-menthenes by acid-catalysed ring opening of pin-2-ene derivatives. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1976;(5):484–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049105425&doi=10.1039%252fP19760000484&partnerID=40&md5=493a355073e69164ab6d72426d57fa13

380.

Mechoulam R. Medicines developed from hashish. Harefuah [Internet]. 1976;90(8):378–80. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017308840&partnerID=40&md5=9f20eff0227d6d449e57218937c3d6be

381.

Mechoulam R, Mccallum NK, Burstein S. Recent Advances in the Chemistry and Biochemistry of Cannabis. Chemical Reviews [Internet]. 1976;76(1):75–112. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017226099&doi=10.1021%252fcr60299a002&partnerID=40&md5=2f7830799f20f6029ff914cfdb5a7190

382.

Lander N, Ben-Zvi Z, Mechoulam R, Martin B, Nordqvist M, Agurell S. Total syntheses of cannabidiol and Δ1-tetrahydrocannabinol metabolites. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1976;(1):8–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016887564&doi=10.1039%252fp19760000008&partnerID=40&md5=cdd0214c994c618584bcc0e17f92a107

383.

Meyer AY, Pasternak R, Sterling J, Lander N, Mechoulam R. Spectral effects in cyclobutane derivatives. The bathochromic-hypochromic shifts in compounds related to verbenone. Tetrahedron [Internet]. 1976;32(22):2805–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0005092517&doi=10.1016%2f0040-4020%2876%2980127-5&partnerID=40&md5=17ae4f9ca2b85c8dd35319774d6deed0

384.

Carlini EA, Mechoulam R, Lander N. Anticonvulsant activity of four oxygenated cannabidiol derivatives. Research Communications in Chemical Pathology and Pharmacology [Internet]. 1975;12(1):1–15. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016769021&partnerID=40&md5=3bddc964f19bbb2d7b5227265107a87d

385.

Banerjee SP, Snyder SH, Mechoulam R. Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1975;194(1):74–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016699656&partnerID=40&md5=554539251e8a58541abad219eb8f42ca

386.

Houry S, Mechoulam R, Loev B. Benzoxocin and Benzoxonin Derivatives. Novel Groups of Terpenophenols with Central Nervous System Activity. A Correction. Journal of Medicinal Chemistry [Internet]. 1975;18(9):951–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016830819&doi=10.1021%252fjm00243a020&partnerID=40&md5=917111eb0b16b81178aa58430bc484e3

387.

Cais M, Dani S, Josephy Y, Modiano A, Gershon H, Mechoulam R. Studies of cannabinoid metabolites - a free radical immunoassay. FEBS Letters [Internet]. 1975;55(1–2):257–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016799476&doi=10.1016%2f0014-5793%2875%2981005-2&partnerID=40&md5=f4b7b276a95dedaae15a7c5cde8d896c

388.

Mechoulam R, Luchter K, Goldblum A. New method for the oxidation of monoketones to 1,3-diketones. Synthesis (Germany) [Internet]. 1974;1974(5):363–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016309761&doi=10.1055%252fs-1974-23324&partnerID=40&md5=35d5be3cf388d49f7d05f9e98f4c3634

389.

Houry S, Mechoulam R, Fowler PJ, Macko E, Loev B. Benzoxocin and Benzoxonin Derivatives. Novel Groups of Terpenophenols with Central Nervous System Activity. Journal of Medicinal Chemistry [Internet]. 1974;17(3):287–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015953460&doi=10.1021%252fjm00249a006&partnerID=40&md5=de683f60dafcea019589231c6c3575f7

390.

Shani A, Mechoulam R. Cannabielsoic acids. Isolation and synthesis by a novel oxidative cyclization. Tetrahedron [Internet]. 1974;30(15):2437–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016289538&doi=10.1016%2fS0040-4020%2801%2997114-5&partnerID=40&md5=2ea42050b104b26d46a4dfbf4935b98e

391.

Mechoulam R, Zvi ZB, Agurell S, Nilsson IM, Nilsson JLG, Edery H, et al. Δ6-Tetrahydrocannabinol-7-oic acid, a urinary Δ6-THC metabolite: Isolation and synthesis. Experientia [Internet]. 1973;29(10):1193–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015864009&doi=10.1007%252fBF01935065&partnerID=40&md5=a71831ad75987b94d9127f8cff8a0111

392.

Nilsson IM, Aqurell S, Nilsson JL, Ohlsson A, Lindgren JE, Mechoulam R. Metabolism of 7-hydroxy- 1(6)-tetrahydrocannabinol in the rabbit. Acta Pharmaceutica Suecica [Internet]. 1973;10(2):97–106. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015625261&partnerID=40&md5=d62ab6d3a51438253efdc16557bb5d5a

393.

Mechoulam R, Ben-Zvi Z, Varconi H, Samuelov Y. Cannabinoid rearrangements. Synthesis of Δ5-tetrahydrocannabinol. Tetrahedron [Internet]. 1973;29(11):1615–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015837107&doi=10.1016%2fS0040-4020%2801%2983406-2&partnerID=40&md5=cd52aac5f3f587d80984eda266b8ab2f

394.

Mechoulam R, Varconi H, Ben-Zvi Z, Edery H, Grunfeld Y. Synthesis and Biological Activity of Five Tetrahydrocannabinol Metabolites. Journal of the American Chemical Society [Internet]. 1972;94(22):7930–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015432732&doi=10.1021%252fja00777a049&partnerID=40&md5=3f699bcf44f7c55fe06e159f62913a8a

395.

Edery H, Grunfeld Y, Porath G, Ben-Zvi Z, Shani A, Mechoulam R. Structure-activity relationships in the tetrahydrocannabinol series. Modifications on the aromatic ring and it the side-chain. Arzneimittel-Forschung/Drug Research [Internet]. 1972;22(11):1995–2003. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015429949&partnerID=40&md5=9a3ea691995bb159f96181ccff54c900

396.

Mechoulam R, Braun P, Gaoni Y, Mechoulam R, Braun P, Gaoni Y, et al. Syntheses of Δ1-Tetrahydrocannabinol and Related Cannabinoids. Journal of the American Chemical Society [Internet]. 1972;94(17):6159–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015520848&doi=10.1021%252fja00772a038&partnerID=40&md5=2e2805f4f914466ea84d7ce226be0773

397.

Nilsson JL, Nilsson IM, Agurell S, Ben-Zvi Z, Mechoulam R. Synthesis of a potential urinary tetrahydrocannabinol metabolite. Acta Pharmaceutica Suecica [Internet]. 1972;9(3):215–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015356115&partnerID=40&md5=555d23616be02a8cf8cf4b75ee0ef66b

398.

Ben-Zvi Z, Mechoulam R, Edery H, Porath G. 6β-hydroxy-Δ1-tetrahydrocannabinol synthesis and biological activity. Science [Internet]. 1971;174(4012):951–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015241580&doi=10.1126%252fscience.174.4012.951&partnerID=40&md5=20a988d645720b8bc92412d368ce3aee

399.

Gaoni Y, Mechoulam R, Gaoni Y, Mechoulam R. The Isolation and Structure of Δ-Tetrahydrocannabinol and Other Neutral Cannabinoids from Hashish. Journal of the American Chemical Society [Internet]. 1971;93(1):217–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015221354&doi=10.1021%252fja00730a036&partnerID=40&md5=ccf2e765dd46083c14e02588a4d94609

400.

Edery H, Grunfeld Y, Ben‐Zvi Z, Mechoulam R. STRUCTURAL REQUIREMENTS FOR CANNABINOID ACTIVITY. Annals of the New York Academy of Sciences [Internet]. 1971;191(1):40–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001850107&doi=10.1111%252fj.1749-6632.1971.tb13985.x&partnerID=40&md5=474737942f829e85278953079dadb1dd

401.

Shani A, Mechoulam R. Photochemical reactions of cannabidiol. Cyclization to Δ1-tetrahydrocannabinol and other trans formations. Tetrahedron [Internet]. 1971;27(3):601–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000953496&doi=10.1016%2fS0040-4020%2801%2990728-8&partnerID=40&md5=f328cb5420cfb19ec6eebc84aabdcb92

402.

Eckstein B, Mechoulam R, Burstein SH. Identification of 5α-Androstane-3α, 17β-diol as a principal metabolite of pregnenolone in rat ovary at onset of puberty. Nature [Internet]. 1970;228(5274):866–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014966624&doi=10.1038%252f228866a0&partnerID=40&md5=4bea3b20426de1d0642ae728abb7147f

403.

Burstein SH, Menezes F, Williamson E, Mechoulam R. Metabolism of Δ1(6)-tetrahydro-cannabinol, an active marihuana constituent. Nature [Internet]. 1970;225(5227):87–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014930654&doi=10.1038%252f225087a0&partnerID=40&md5=d2aabd50a94f549520cf8d28835ad48f

404.

Ben-Zvi Z, Mechoulam R, Burstein S. Identification through Synthesis of an Active∆1(6)-Tetrahydrocannabinol Metabolite. Journal of the American Chemical Society [Internet]. 1970;92(11):3468–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014931142&doi=10.1021%252fja00714a043&partnerID=40&md5=e2c4987a2ea071aea91493637b431970

405.

Mechoulam R, Shani A, Edery H, Grunfeld Y. Chemical basis of hashish activity. Science [Internet]. 1970;169(3945):611–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014936107&doi=10.1126%252fscience.169.3945.611&partnerID=40&md5=5ce49d7839d291dcb2fd3c7a73e5b464

406.

Mechoulam R. Marihuana chemistry. Science [Internet]. 1970;168(3936):1159–66. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014933381&doi=10.1126%252fscience.168.3936.1159&partnerID=40&md5=64dbbaec95757961953be5e2583f36e9

407.

Ben-Zvi Z, Mechoulam R, Burstein SH. Synthesis of Δ1 and Δ1(6) tetrahydrocannabinol metabolites. Tetrahedron Letters [Internet]. 1970;11(51):4495–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014872243&doi=10.1016%2fS0040-4039%2801%2983959-9&partnerID=40&md5=f1e334f3e3745cd26f7f6a3849350763

408.

Shani A, Mechoulam R. A new type of cannabinoid. Synthesis of cannabielsoic acid A by a novel photo-oxidative cyclisation. Journal of the Chemical Society D: Chemical Communications [Internet]. 1970;(5):273–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0012262921&doi=10.1039%252fC29700000273&partnerID=40&md5=39f5f180cab9a79fb92f2158007c4399

409.

Mechoulam R, Ben-Zvi Z. Carboxylation of resorcinols with methylmagnesium carbonate. Synthesis of cannabinoid acids. Analytical Proceedings [Internet]. 1969;(7):343–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049125013&doi=10.1039%252fC29690000343&partnerID=40&md5=9243d337c00a639d9fc46898893ef1bb

410.

Yagen B, Mechoulam R. Stereospecific cyclizations and isomerizations of cannabichromene and related cannabinoids. Tetrahedron Letters [Internet]. 1969;10(60):5353–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014632753&doi=10.1016%2fS0040-4039%2801%2988962-0&partnerID=40&md5=e8a868fd5fa530c5a1b73b6b2131edbc

411.

Mechoulam R, Yagen B. Stereoselective cyclizations of cannabinoid 1,5 dienes. Tetrahedron Letters [Internet]. 1969;10(60):5349–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014625077&doi=10.1016%2fS0040-4039%2801%2988961-9&partnerID=40&md5=1c5941e23c887c35f5e99450ea500a50

412.

Mechoulam R, Ben-Zvi Z, Yagnitinsky B, Shani A. A new tetrahydrocannabinolic acid. Tetrahedron Letters [Internet]. 1969;10(28):2339–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014525511&doi=10.1016%2fS0040-4039%2801%2988158-2&partnerID=40&md5=7a47cb59e18c3b7ae7b6c721030e8cc3

413.

Bicher HI, Mechoulam R. Pharmacological effects of two active constituents of marihuana. Archives internationales de pharmacodynamie et de therapie [Internet]. 1968;172(1):24–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014259848&partnerID=40&md5=2752ec6fad92f13c47291edfc4d21eed

414.

Gaoni Y, Mechoulam R. The ISO‐Tetrahydrocannabinols. Israel Journal of Chemistry [Internet]. 1968;6(5):679–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84989993955&doi=10.1002%252fijch.196800086&partnerID=40&md5=a0f93184c7ad718620e4b216bb0533e8

415.

Mechoulam R. Tetrazolo Steroids. Israel Journal of Chemistry [Internet]. 1968;6(6):909–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845347354&doi=10.1002%252fijch.196800114&partnerID=40&md5=734ea14e9075e13448cad6ab225dc26b

416.

Mechoulam R, Yagnitinsky B, Gaoni Y. Stereoelectronic Factor in the Chloranil Dehydrogenation of Cannabinoids. Total Synthesis of dl-Cannabichromene. Journal of the American Chemical Society [Internet]. 1968;90(9):2418–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014428425&doi=10.1021%252fja01011a037&partnerID=40&md5=73879d22ca2f1025d8924f2727a2b7de

417.

Burstein S, Mechoulam R. Stereospecifically Labeled Δ1(6)-Tetrahydrocannabinol. Journal of the American Chemical Society [Internet]. 1968;90(9):2420–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014428415&doi=10.1021%252fja01011a038&partnerID=40&md5=fa33ab3ba8566c017d21714d9a7113f6

418.

Crombie L, Ponsford R, Shani A, Yagnitinsky B, Mechoulam R. Hashish components. Photochemical production of cannabicyclol from cannabichromene. Tetrahedron Letters [Internet]. 1968;9(55):5771–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014351938&doi=10.1016%2fS0040-4039%2800%2976346-5&partnerID=40&md5=d05d27c08e6e433301cbfb8beef31665

419.

Mechoulam R, Ben-Zvi Z, Gaoni Y. Hashish-XIII. On the nature of the beam test. Tetrahedron [Internet]. 1968;24(16):5615–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014314776&doi=10.1016%2f0040-4020%2868%2988159-1&partnerID=40&md5=ee445b4c7ce6a5473af0a91114ec2263

420.

Mechoulam R, Braun P, Gaoni Y. A Stereospecific Synthesis of (—)-Δ1- and (—)-Δ11(6)-Tetrahydrocannabinols. Journal of the American Chemical Society [Internet]. 1967;89(17):4552–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014208456&doi=10.1021%252fja00993a072&partnerID=40&md5=ce83e72b8026e370792e9a65ec66b2f1

421.

Mechoulam R, Gaoni Y. Recent advances in the chemistry of hashish. Fortschritte der Chemie organischer Naturstoffe Progress in the chemistry of organic natural products Progrès dans la chimie des substances organiques naturelles [Internet]. 1967;25:175–213. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014189130&doi=10.1007%252f978-3-7091-8164-5_6&partnerID=40&md5=1cf7ace37c5aa62dad39ecad7de541f6

422.

Mechoulam R, Gaoni Y. The absolute configuration of δ1-tetrahydrocannabinol, the major active constituent of hashish. Tetrahedron Letters [Internet]. 1967;8(12):1109–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014061503&doi=10.1016%2fS0040-4039%2800%2990646-4&partnerID=40&md5=0c1706565b9ac759fc225c168f1de3d6

423.

Mechoulam R, Hirshfeld A. The synthesis of zapotidine. Tetrahedron [Internet]. 1967;23(1):239–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014042771&doi=10.1016%2fS0040-4020%2801%2983305-6&partnerID=40&md5=4dc2de56081dbc1830926d5fb88d8329

424.

Gaoni Y, Mechoulam R. Cannabichromene, a new active principle in hashish. Chemical Communications (London) [Internet]. 1966;(1):20–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013220058&doi=10.1039%252fC19660000020&partnerID=40&md5=b096fe0778be52ced4ddee0ea5ac2397

425.

Gaoni Y, Mechoulam R. Concerning the Isomerization of Δ1-to A1(6)-TetrahydrocannabinoI. Journal of the American Chemical Society [Internet]. 1966;88(23):5673–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0012260213&doi=10.1021%252fja00975a071&partnerID=40&md5=500448b27f12b2972c6e2f6b401548a0

426.

Gaoni Y, Mechoulam R. Hashish-VII. The isomerization of cannabidiol to tetrahydrocannabinols. Tetrahedron [Internet]. 1966;22(4):1481–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001260384&doi=10.1016%2fS0040-4020%2801%2999446-3&partnerID=40&md5=2a310c758026630396147e2c4b623b38

427.

Mechoulam R, Gaoni Y. Erratum: A total synthesis of dl-Δ′-tetrahydrocannabinol, the active constituent of harnish (Journal of the American Chemical Society (1965) 87 (3274)). Journal of the American Chemical Society [Internet]. 1965;87(24):5811. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947484820&partnerID=40&md5=43c41911cbd29f70dfa332a020921e03

428.

Mechoulam R, Gaoni Y. A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish. Journal of the American Chemical Society [Internet]. 1965;87(14):3273–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001123407&doi=10.1021%252fja01092a065&partnerID=40&md5=9bb29ec93a14a9617e5e1c7222394e7d

429.

Budzikiewicz H, Alpin RT, Lightner DA, Djerassi C, Mechoulam R, Gaoni Y. Massenspektroskopie und IHRE anwendung auf strukturelle und stereochemische probleme-LXVIII. Massenspektroskopische untersuchung der inhaltstoffe von haschisch. Tetrahedron [Internet]. 1965;21(7):1881–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013786160&doi=10.1016%2fS0040-4020%2801%2998657-0&partnerID=40&md5=f34e88bcf3d2c3353cf17981ff9ad2b9

430.

Mechoulam R, Gaoni Y. Hashish-IV. The isolation and structure of cannabinolic cannabidiolic and cannabigerolic acids. Tetrahedron [Internet]. 1965;21(5):1223–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013779962&doi=10.1016%2f0040-4020%2865%2980064-3&partnerID=40&md5=3fca33fcd5cf9bb426ec90791b410e59

431.

Gaoni Y, Mechoulam R. The structure and synthesis of cannabigerol, a new hashish constituent. Proceedings of the Chemical Society [Internet]. 1964;(MARCH):82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-27444431791&partnerID=40&md5=fbd056a1d1b2d85c9d982a0d6cf24fac

432.

Gaoni Y, Mechoulam R. Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish. Journal of the American Chemical Society [Internet]. 1964;86(8):1646–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947489961&doi=10.1021%252fja01062a046&partnerID=40&md5=6f800ebfaf57467779f202224e291fec

433.

Sondheimer F, Mechoulam R, Sprecher M. The synthesis of 10-hydroxy-10α-testosterone. Tetrahedron [Internet]. 1964;20(11):2473–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013771371&doi=10.1016%2fS0040-4020%2801%2990827-0&partnerID=40&md5=cc7ea509eea7d9740093a341df1312be

434.

Mechoulam R, Gaoni Y. Pesticides. I. the structure of dihydronicotyrine. Recueil des Travaux Chimiques des Pays‐Bas [Internet]. 1963;82(12):1159–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982075823&doi=10.1002%252frecl.19630821203&partnerID=40&md5=dcb2222324e86e8c0e7486fa6becffb2

435.

Mechoulam R, Shvo Y. Hashish-I. The structure of Cannabidiol. Tetrahedron [Internet]. 1963;19(12):2073–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013768939&doi=10.1016%2f0040-4020%2863%2985022-X&partnerID=40&md5=c083a0c2caa88ea32355f5f2086c1c18

436.

Mechoulam R, Danieli N, Mazur Y. The structure and synthesis of oleuropeic acid. Tetrahedron Letters [Internet]. 1962;3(16):709–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-50549157399&doi=10.1016%2fS0040-4039%2800%2970937-3&partnerID=40&md5=eee63cbdfb33e6288414cbbef9a539a5

437.

Mechoulam R, Sondheimer F, Melera A, Kincl FA. The structure of zapotidine. Journal of the American Chemical Society [Internet]. 1961;83(8):2022–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0008301410&doi=10.1021%252fja01469a064&partnerID=40&md5=2104f2338e8a7b8416d79c61ce4b5077

438.

Sondheimer F, Mechoulam R, Sprecher M. 19-hydroxy-10-isotestosterone. Tetrahedron Letters [Internet]. 1960;1(43):38–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-50549155206&doi=10.1016%2fS0040-4039%2801%2999376-1&partnerID=40&md5=c3d2be9bc0a163669509f8e2e7fcddfa

439.

Sondheimer F, Burstein S, Mechoulam R. Syntheses in the Cardiac Aglycone Field. III.1 The Conversion of a 14α- to a 14β-Hydroxy Group in the Androstane Series. The Ultraviolet Spectra of Δ15-Androsten-17-ones. Journal of the American Chemical Society [Internet]. 1960;82(12):3209–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0002835031&doi=10.1021%252fja01497a055&partnerID=40&md5=4af960c7dfc99ab558fe183da79e5694

440.

Sondheimer F, Mechoulam R. The Diels-Alder reaction of steroidal 20-methylene-Δ16-pregnene derivatives with maleic anhydride. Journal of Organic Chemistry [Internet]. 1959;24(1):106–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947470646&partnerID=40&md5=90976a0b7c579524cc2018095823a36c

441.

Mechoulam R, Sondheimer F. The Wittig Reaction with Fluorenone. Formation of Cyclopropane Derivatives. Journal of the American Chemical Society [Internet]. 1958;80(16):4386–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0005298106&doi=10.1021%252fja01549a069&partnerID=40&md5=9ba283242e352061288cd838f8e06b41

442.

Sondheimer F, Mechoulam R. Further Aspects of the Wittig Reaction in the Steroid Series. 20-Dehydrocholesterol and 20-Isocholesterol. Journal of the American Chemical Society [Internet]. 1958;80(12):3087–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-5244250932&doi=10.1021%252fja01545a046&partnerID=40&md5=6c9ea863daa0e67bac793daa7a2a7de6

443.

Sondheimer F, Mechoulam R. Synthesis of Steroidal Methylene Compounds by the Wittig Reaction. Journal of the American Chemical Society [Internet]. 1957;79(18):5029–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021466338&doi=10.1021%252fja01575a054&partnerID=40&md5=71e307a263704b473f418806628bac21

444.

Cohen S, Kaluszyner A, Mechoulam R. On the Fluorination of DDT with Hydrogen Fluoride and Mercuric Oxide. Journal of the American Chemical Society [Internet]. 1957;79(22):5979–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947462075&doi=10.1021%252fja01579a036&partnerID=40&md5=634a8eb076cc6017b7e9e8a44cb1339c