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The Faculty of Medicine - Biochemistry and Molecular Biology: Yedgar Saul


 Last updated December 2021 - Biochemistry and Molecular Biology 

List of Publications

(1) Barshtein G, Zelig O, Gural A, Arbell D, Yedgar S. Determination of red blood cell adhesion to vascular endothelial cells: A critical role for blood plasma. Colloids Surf B Biointerfaces 2021.

(2) Arbell D, Bin-Nun A, Zugayar D, Eventov-Friedman S, Chepel N, Srebnik N, et al. Deformability of cord blood vs. newborns’ red blood cells: implication for blood transfusion. J Matern -Fetal Neonatal Med 2021.

(3) Barshtein G, Rasmusen TL, Zelig O, Arbell D, Yedgar S. Inter-donor variability in deformability of red blood cells in blood units. Transfus Med 2020;30(6):492-496.

(4) Barshtein G, Gural A, Zelig O, Arbell D, Yedgar S. Unit-to-unit variability in the deformability of red blood cells. Transfus Apheresis Sci 2020;59(5).

(5) Koshkaryev A, Livshits L, Pajic-Lijakovic I, Gural A, Barshtein G, Yedgar S. Non-oxidative band-3 clustering agents cause the externalization of phosphatidylserine on erythrocyte surfaces by a calcium-independent mechanism. Biochim Biophys Acta Biomembr 2020;1862(6).

(6) Barshtein G, Gural A, Zelig O, Arbell D, Yedgar S. Preparation of packed red blood cell units in the blood bank: Alteration in red blood cell deformability. Transfus Apheresis Sci 2020;59(3).

(7) McVey MJ, Kuebler WM, Orbach A, Arbell D, Zelig O, Barshtein G, et al. Reduced deformability of stored red blood cells is associated with generation of extracellular vesicles. Transfus Apheresis Sci 2020.

(8) Biran R, Hadayer N, Ramot Y, Zlotogorski A, Yedgar S, Barshtein G. Phototherapy decreases red blood cell deformability in patients with psoriasis. Clin Hemorheol Microcirc 2020;73(4):489-496.

(9) Yedgar S, Arbell D, Barshtein G. Hemodynamic Functionality of Stored Red Blood Cells: An Important Metric of Blood Unit Quality. Ann Thorac Surg 2019;108(5):1587-1588.

(10) Arbell D, Gertzulin M, Zelig O, Wexler TLR, Barshtein G, Yedgar S. Risk of red cell exposure to the water anomaly upon blood unit cold-storage. Am J Hematol 2018;93(12):E397-E398.

(11) Barshtein G, Arbell D, Yedgar S. Hemodynamic functionality of transfused red blood cells in the microcirculation of blood recipients. Front Physiol 2018;9(JAN).

(12) Barshtein G, Goldschmidt N, Pries AR, Zelig O, Arbell D, Yedgar S. Deformability of transfused red blood cells is a potent effector of transfusion-induced hemoglobin increment: A study with β-thalassemia major patients. Am J Hematol 2017;92(9):E559-E560.

(13) David M, Levy E, Feldman Y, Ben Ishai P, Zelig O, Yedgar S, et al. The dielectric spectroscopy of human red blood cells: The differentiation of old from fresh cells. Physiol Meas 2017;38(7):1335-1348.

(14) Orbach A, Zelig O, Yedgar S, Barshtein G. Biophysical and Biochemical Markers of Red Blood Cell Fragility. Transfus Med Hemotherapy 2017;44(3):183-187.

(15) Levy E, David M, Barshtein G, Yedgar S, Livshits L, Ben Ishai P, et al. Dielectric Response of Cytoplasmic Water and Its Connection to the Vitality of Human Red Blood Cells. II. the Influence of Storage. J Phys Chem B 2017;121(20):5273-5278.

(16) Harel-Dassa K, Yedgar S, Tropé CG, Davidson B, Reich R. Phospholipase D messenger RNA expression and clinical role in high-grade serous carcinoma. Hum Pathol 2017;62:115-121.

(17) Rivkin N, Chapnik E, Mildner A, Barshtein G, Porat Z, Kartvelishvily E, et al. Erythrocyte survival is controlled by microRNA-142. Haematologica 2017;102(4):676-685.

(18) Barshtein G, Pries AR, Goldschmidt N, Zukerman A, Orbach A, Zelig O, et al. Deformability of transfused red blood cells is a potent determinant of transfusion-induced change in recipient's blood flow. Microcirculation 2016;23(7):479-486.

(19) Cahn A, Livshits L, Srulevich A, Raz I, Yedgar S, Barshtein G. Diabetic foot disease is associated with reduced erythrocyte deformability. Int Wound J 2016;13(4):500-504.

(20) Barshtein G, Livshits L, Shvartsman LD, Shlomai NO, Yedgar S, Arbell D. Polystyrene Nanoparticles Activate Erythrocyte Aggregation and Adhesion to Endothelial Cells. Cell Biochem Biophys 2016;74(1):19-27.

(21) Mruwat R, Kivity S, Landsberg R, Yedgar S, Langier S. Phospholipase A2-dependent release of inflammatory cytokines by superantigen-stimulated nasal polyps of patients with chronic rhinosinusitis. Am J Rhinol and Allergy 2015;29(5):e122-e128.

(22) Barshtein G, Gural A, Manny N, Zelig O, Yedgar S, Arbell D. Storage-induced damage to red blood cell mechanical properties can be only partially reversed by rejuvenation. Transfus Med Hemotherapy 2014;41(3):197-204.

(23) Mruwat R, Yedgar S, Lavon I, Ariel A, Krimsky M, Shoseyov D. Phospholipase A2 in experimental allergic bronchitis: A lesson from mouse and rat models. PLoS ONE 2013;8(10).

(24) Mruwat R, Cohen Y, Yedgar S. Phospholipase A2 inhibition as potential therapy for inflammatory skin diseases. Immunother 2013;5(4):315-317.

(25) Matot I, Katz M, Pappo O, Zelig O, Corchia N, Yedgar S, et al. Resuscitation with aged blood exacerbates liver injury in a hemorrhagic rat model. Crit Care Med 2013;41(3):842-849.

(26) Livshits L, Srulevich A, Raz I, Cahn A, Barshtein G, Yedgar S, et al. Effect of short-term hyperglycemia on protein kinase C alpha activation in human erythrocytes. Rev Diabetic Stud 2012;9(2-3):1-23.

(27) Dan P, Rosenblat G, Yedgar S. Phospholipase A2 activities in skin physiology and pathology. Eur J Pharmacol 2012;691(1-3):1-8.

(28) Arbel Y, Banai S, Benhorin J, Finkelstein A, Herz I, Halkin A, et al. Erythrocyte aggregation as a cause of slow flow in patients of acute coronary syndromes. Int J Cardiol 2012;154(3):322-327.

(29) Livshits L, Srulevich A, Raz I, Cahn A, Barshtein G, Yedgar S, et al. Effect of short-term hyperglycemia on protein kinase C alpha activation in human erythrocytes. Rev Diabet Stud 2012;9(2-3):94-103.

(30) Otuki MF, Schwob O, Silveira Prudente A, Zaltsman I, Meretski S, Segal J, et al. Attenuation of experimental TPA-induced dermatitis by acetylenic acetogenins is associated with inhibition of PLA 2 activity. Eur J Pharmacol 2011;672(1-3):175-179.

(31) Barshtein G, Arbell D, Yedgar S. Hemolytic effect of polymeric nanoparticles: Role of albumin. IEEE Trans Nanobiosci 2011;10(4):259-261.

(32) Barshtein G, Manny N, Yedgar S. Circulatory Risk in the Transfusion of Red Blood Cells With Impaired Flow Properties Induced by Storage. Transfus Med Rev 2011;25(1):24-35.

(33) Schlager A, Zamir G, Barshtein G, Yedgar S, Arbell D. Plasma Factor in Red Blood Cells Adhesion to Endothelial Cells: Humans and Rats. Cell Biochem Biophys 2010;58(3):157-161.

(34) Koshkaryev A, Barshtein G, Yedgar S. Vitamin E induces phosphatidylserine externalization and red cell adhesion to endothelial cells. Cell Biochem Biophys 2010;56(2):109-114.

(35) Koshkaryev A, Zelig O, Manny N, Yedgar S, Barshtein G. Rejuvenation treatment of stored red blood cells reverses storage-induced adhesion to vascular endothelial cells. Transfusion 2009;49(10):2136-2143.

(36) Maharshak N, Arbel Y, Shapira I, Berliner S, Ben-Ami R, Yedgar S, et al. Increased strength of erythrocyte aggregates in blood of patients with inflammatory bowel disease. Inflammatory Bowel Dis 2009;15(5):707-713.

(37) Yedgar S, Kaul DK, Barshtein G. RBC adhesion to vascular endothelial cells: More potent than RBC aggregation in inducing circulatory disorders. Microcirculation 2008;15(7):581-583.

(38) Adar T, Ben-Ami R, Elstein D, Zimran P, Berliner S, Yedgar S, et al. Increased red blood cell aggregation in patients with Gaucher disease is non-inflammatory. Clin Hemorheol Microcirc 2008;40(2):113-118.

(39) Kaul DK, Koshkaryev A, Artmann G, Barshtein G, Yedgar S. Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance. Am J Physiol Heart Circ Physiol 2008;295(4):H1788-H1793.

(40) Gluck N, Schwob O, Krimsky M, Yedgar S. Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation. Am J Physiol Cell Physiol 2008;294(6):C1597-C1603.

(41) Arbell D, Orkin B, Bar-Oz B, Barshtein G, Yedgar S. Premature red blood cells have decreased aggregation and enhanced aggregability. J Physiol Sci 2008;58(3):161-165.

(42) Ramot Y, Koshkaryev A, Goldfarb A, Yedgar S, Barshtein G. Phenylhydrazine as a partial model for β-thalassaemia red blood cell hemodynamic properties. Br J Haematol 2008;140(6):692-700.

(43) Dan P, Dagan A, Krimsky M, Pruzanski W, Vadas P, Yedgar S. Inhibition of type I and type II phospholipase A2 by phosphatidyl-ethanolamine linked to polymeric carriers (Biochemistry (1998) 37, 17, (6199-6204)). Biochemistry 2008;47(2):857.

(44) Gorovetz M, Schwob O, Krimsky M, Yedgar S, Reich R. MMP production in human fibrosarcoma cells and their invasiveness are regulated by group IB secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2. Front Biosci 2008;13(5):1917-1925.

(45) Relevy H, Koshkaryev A, Manny N, Yedgar S, Barshtein G. Blood banking-induced alteration of red blood cell flow properties. Transfusion 2008;48(1):136-146.

(46) Yedgar S, Krimsky M, Cohen Y, Flower RJ. Treatment of inflammatory diseases by selective eicosanoid inhibition: a double-edged sword? Trends Pharmacol Sci 2007;28(9):459-464.

(47) Barshtein G, Ben-Ami R, Yedgar S. Role of red blood cell flow behavior in hemodynamics and hemostasis. Exp Rev Cardiovasc Ther 2007;5(4):743-752.

(48) Ingber A, Cohen Y, Krimsky M, Yedgar S. A novel treatment of contact dermatitis by topical application of phospholipase A2 inhibitor: A double-blind placebo-controlled pilot study. Int J Immunopathol Pharmacol 2007;20(1):191-195.

(49) Yedgar S, Cohen Y, Shoseyov D. Control of phospholipase A2 activities for the treatment of inflammatory conditions. Biochim Biophys Acta Mol Cell Biol Lipids 2006;1761(11):1373-1382.

(50) Adar T, Ben-Ami R, Elstein D, Zimran A, Berliner S, Yedgar S, et al. Aggregation of red blood cells in patients with Gaucher disease. Br J Haematol 2006;134(4):432-437.

(51) Schechner V, Ben-Ami R, Hershcovici T, Yedgar S, Beigel Y, Shapira I, et al. Plasma dependent reduction in red blood cell aggregation after dextran sulfate low-density lipoprotein apheresis - Implications for rheological studies. Ther Apheresis Dial 2005;9(5):379-384.

(52) Shoseyov D, Bibi H, Offer S, Schwob O, Krimsky M, Kleiman M, et al. Treatment of ovalbumin-induced experimental allergic bronchitis in rats by inhaled inhibitor of secretory phospholipase A2. Thorax 2005;60(9):747-753.

(53) Nyska M, Shabat S, Long PH, Howard C, Ezov N, Levin-Harrus T, et al. Disseminated thrombosis-induced growth plate necrosis in rat: A unique model for growth plate arrest. J Pediatr Orthop 2005;25(3):346-350.

(54) Offer S, Yedgar S, Schwob O, Krimsky M, Bibi H, Eliraz A, et al. Negative feedback between secretory and cytosolic phospholipase A 2 and their opposing roles in ovalbumin-induced bronchoconstriction in rats. Am J Physiol Lung Cell Mol Physiol 2005;288(3 32-3):L523-L529.

(55) Samocha-Bonet D, Ben-Ami R, Shapira I, Shenkerman G, Abu-Abeid S, Stern N, et al. Flow-resistant red blood cell aggregation in morbid obesity. Int J Obes 2004;28(12):1528-1534.

(56) Berliner S, Ben-Ami R, Samocha-Bonet D, Abu-Abeid S, Schechner V, Beigel Y, et al. The degree of red blood cell aggregation on peripheral blood glass slides corresponds to inter-erythrocyte cohesive forces in laminar flow. Thromb Res 2004;114(1):37-44.

(57) Darville T, Yedgar S, Krimsky M, Andrews Jr. CW, Jungas T, Ojcius DM. Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-bound glycosaminoglycans. Microbes Infect 2004;6(4):369-376.

(58) Chen W, Li L, Zhu J, Liu J, Soria J, Soria C, et al. Control of angiogenesis by inhibitor of phospholipase A2. Chin Med Sci J 2004;19(1):6-12.

(59) Shabat S, Nyska A, Long PH, Goelman G, Abramovitch R, Ezov N, et al. Osteonecrosis in a Chemically Induced Rat Model of Human Hemolytic Disorders Associated with Thrombosis - A New Model for Avascular Necrosis of Bone. Calcif Tissue Int 2004;74(3):220-228.

(60) Barshtein G, Ponizovsky AM, Nechamkin Y, Ritsner M, Yedgar S, Bergelson LD. Aggregability of red blood cells of schizophrenia patients with negative syndrome is selectively enhanced. Schizophr Bull 2004;30(4):913-922.

(61) Pinto F, Brenner T, Dan P, Krimsky M, Yedgar S. Extracellular Phospholipase A2 Inhibitors Suppress Central Nervous System Inflammation. Glia 2003;44(3):275-282.

(62) Koshkaryev A, Yedgar S, Relevy H, Fibach E, Barshtein G. Acridine orange induces translocation of phosphatidylserine to red blood cell surface. Am J Physiol Cell Physiol 2003;285(3 54-3):C720-C722.

(63) Krimsky M, Yedgar S, Aptekar L, Schwob O, Goshen G, Gruzman A, et al. Amelioration of TNBS-induced colon inflammation in rats by phospholipase A2 inhibitor. Am J Physiol Gastrointest Liver Physiol 2003;285(3 48-3):G586-G592.

(64) Koshkaryev A, Barshtein G, Nyska A, Ezov N, Levin-Harrus T, Shabat S, et al. 2-Butoxyethanol enhances the adherence of red blood cells. Arch Toxicol 2003;77(8):465-469.

(65) Beck GC, Hermes WC, Yard BA, Kaszkin M, Von Zabern D, Schulte J, et al. Amelioration of endotoxin-induced sepsis in rats by membrane anchored lipid conjugates. Crit Care Med 2003;31(7):2015-2021.

(66) Nyska A, Moomaw CR, Ezov N, Shabat S, Levin-Harrus T, Nyska M, et al. Ocular expression of vascular cell adhesion molecule (VCAM-1) in 2-butoxyethanol-induced hemolysis and thrombosis in female rats. Exp Toxicol Pathol 2003;55(4):231-236.

(67) Ben-Ami R, Barshtein G, Mardi T, Deutch V, Elkayam O, Yedgar S, et al. A synergistic effect of albumin and fibrinogen on immunoglobulin-induced red blood cell aggregation. Am J Physiol Heart Circ Physiol 2003;285(6 54-6):H2663-H2669.

(68) Yedgar S, Krimsky M, Schwob O. Protection of cell membrane from exogenous PLA2 and related inflammatory stimuli by membrane-anchored lipid conjugates. Adv Exp Med Biol 2003;525:97-101.

(69) Gamzu R, Barshtein G, Tsipis F, Lessing JB, Berliner AS, Kupferminc MJ, et al. Pregnancy-induced hypertension is associated with elevation of aggregability of red blood cells. Clin Hemorheol Microcirc 2002;27(3-4):163-169.

(70) Yedgar S, Koshkaryev A, Barshtein G. The red blood cell in vascular occlusion. Pathophysiol Haemost Thromb 2002;32(5-6):263-268.

(71) Ezov N, Levin-Harrus T, Mittelman M, Redlich M, Shabat S, Ward SM, et al. A chemically induced rat model of hemolysis with disseminated thrombosis. Cardiovasc Toxicol 2002;2(3):181-193.

(72) Beck GC, Yard BA, Schulte J, Oberacker R, Van Ackern K, Van Der Woude FJ, et al. Inhibition of LPS-induced chemokine production in human lung endothelial cells by lipid conjugates anchored to the membrane. Br J Pharmacol 2002;135(7):1665-1674.

(73) Chen WM, Soria J, Soria C, Krimsky M, Yedgar S. Control of capillary formation by membrane-anchored extracellular inhibitor of phospholipase A2. FEBS Lett 2002;522(1-3):113-118.

(74) Yard BA, Yedgar S, Scheele M, Van Der Woude D, Beck G, Heidrich B, et al. Modulation of IFN-γ-induced immunogenicity by phosphatidylethanolamine-linked hyaluronic acid. Transplantation 2002;73(6):984-992.

(75) Ben-Ami R, Sheinman G, Yedgar S, Eldor A, Roth A, Berliner AS, et al. Thrombolytic therapy reduces red blood cell aggregation in plasma without affecting intrinsic aggregability. Thromb Res 2002;105(6):487-492.

(76) Ginsburg I, Sadovnic M, Yedgar S, Kohen R, Hrbac J. Hemolysis of human erythrocytes by hypochlorous acid is modulated by amino acids, antioxidants, oxidants, membrane-perforating agents and by divalent metals. Free Radic Res 2002;36(6):607-619.

(77) Ponizovsky AM, Modai I, Nechamkin Y, Barshtein G, Ritsner MS, Yedgar S, et al. Phospholipid patterns of erythrocytes in schizophrenia: Relationships to symptomatology. Schizophr Res 2001;52(1-2):121-126.

(78) Ami RB, Barshtein G, Zeltser D, Goldberg Y, Shapira I, Roth A, et al. Parameters of red blood cell aggregation as correlates of the inflammatory state. Am J Physiol Heart Circ Physiol 2001;280(5 49-5):H1982-H1988.

(79) Nitzan DW, Nitzan U, Dan P, Yedgar S. The role of hyaluronic acid in protecting surface-active phospholipids from lysis by exogenous phospholipase A2. Rheumatology (UK) 2001;40(3):336-340.

(80) Yedgar S, Lichtenberg D, Schnitzer E. Inhibition of phospholipase A2 as a therapeutic target. Biochim Biophys Acta Mol Cell Biol Lipids 2000;1488(1-2):182-187.

(81) Balsinde J, Balboa MA, Yedgar S, Dennis EA. Group V phospholipase A2-mediated oleic acid mobilization in lipopolysaccharide-stimulated P388D1 macrophages. J Biol Chem 2000;275(7):4783-4786.

(82) Schnitzer E, Dagan A, Krimsky M, Lichtenberg D, Pinchuk I, Shinar H, et al. Interaction of hyaluronic acid-linked phosphatidylethanolamine (HyPE) with LDL and its effect on the susceptibility of LDL lipids to oxidation. Chem Phys Lipids 2000;104(2):149-160.

(83) Barshtein G, Wajnblum D, Yedgar S. Kinetics of linear rouleaux formation studied by visual monitoring of red cell dynamic organization. Biophys J 2000;78(5):2470-2474.

(84) Krimsky M, Dagan A, Yedgar S, Aptekar L, Ligumsky M. Assessment Of Intestinal Permeability In Rats By Permeation Of Inulin-Fluorescein. J Basic Clin Physiol Pharmacol 2000;11(2):143-154.

(85) Yedgar S, Hovav T, Barshtein G. Red blood cell intercellular interactions in oxidative stress states. Clin Hemorheol Microcirc 1999;21(3-4):189-193.

(86) Hovav T, Goldfarb A, Artmann G, Yedgar S, Barshtein G. Enhanced adherence of β-thalassaemic erythrocytes to endothelial cells. Br J Haematol 1999;106(1):178-181.

(87) Hovav T, Yedgar S, Manny N, Barshtein G. Alteration of red cell aggregability and shape during blood storage. Transfusion 1999;39(3):277-281.

(88) Abu-Raya S, Bloch-Shilderman E, Shohami E, Trembovler V, Shai Y, Weidenfeld J, et al. Pardaxin, a new pharmacological tool to stimulate the arachidonic acid cascade in PC12 cells. J Pharmacol Exp Ther 1998;287(3):889-896.

(89) Taylor WF, Chen S, Barshtein G, Hyde DE, Yedgar S. Enhanced aggregability of human red blood cells by diving. Undersea Hyperbaric Med 1998;25(3):167-170.

(90) Schnitzer E, Pinchuk I, Fainaru M, Lichtenberg D, Yedgar S. LDL-associated phospholipase a does not protect LDL against lipid peroxidation in vitro. Free Radic Biol Med 1998;24(7-8):1294-1303.

(91) Dan P, Dagan A, Krimsky M, Pruzanski W, Vadas P, Yedgar S. Inhibition of type I and type II phospholipase A2 by phosphatidyl- ethanolamine linked to polymeric carriers. Biochemistry 1998;37(17):6199-6204.

(92) Barshtein G, Tamir I, Yedgar S. Red blood cell rouleaux formation in dextran solution: Dependence on polymer conformation. Eur Biophys J 1998;27(2):177-181.

(93) Almagor A, Priev A, Barshtein G, Gavish B, Yedgar S. Reduction of protein volume and compressibility by macromolecular cosolvents: Dependence on the cosolvent molecular weight. Biochim Biophys Acta Protein Struct Mol Enzymol 1998;1382(1):151-156.

(94) Tuvia S, Almagor A, Bitler A, Levin S, Korenstein R, Yedgar S. Cell membrane fluctuations are regulated by medium macroviscosity: Evidence for a metabolic driving force. Proc Natl Acad Sci U S A 1997;94(10):5045-5049.

(95) Barshtein G, Bergelson L, Dagan A, Gratton E, Yedgar S. Membrane lipid order of human red blood cells is altered by physiological levels of hydrostatic pressure. Am J Physiol 1997;272(1 PART 2):H485-H492.

(96) Ben-Hur E, Barshtein G, Chen S, Yedgar S. Photodynamic Treatment of Red Blood Cell Concentrates for Virus Inactivation Enhances Red Blood Cell Aggregation: Protection with Antioxidants. Photochem Photobiol 1997;66(4):509-512.

(97) Barshtein G, Bergelson L, Dagan A, Gratton E, Yedgar S. Membrane lipid order of human red blood cells is altered by physiological levels of hydrostatic pressure. Am J Physiol Heart Circ Physiol 1997;272(1 41-1):H538-H543.

(98) Ginsburg I, Yedgar S, Varani J. Diethyldithiocarbamate and nitric oxide synergize with oxidants and with membrane-damaging agents to injure mammalian cells. Free Radic Res 1997;27(2):143-164.

(99) Dan P, Nitzan DW, Dagan A, Ginsburg I, Yedgar S. H2O2 renders cells accessible to lysis by exogenous phospholipase A2: A novel mechanism for cell damage in inflammatory processes. FEBS Lett 1996;383(1-2):75-78.

(100) Priev A, Almagor A, Yedgar S, Gavish B. Glycerol decreases the volume and compressibility of protein interior. Biochemistry 1996;35(7):2061-2066.

(101) Chen S, Eldor A, Barshtein G, Zhang S, Goldfarb A, Rachmilewitz E, et al. Enhanced aggregability of red blood cells of β-thalassemia major patients. Am J Physiol Heart Circ Physiol 1996;270(6 39-6):H1951-H1956.

(102) Barshtein G, Yedgar S, Bergelson L, Gratton E. Human Red Blood Cell Shape and Volume are Changed by Physiological levels of Hydrostatic Pressure. J Basic Clin Physiol Pharmacol 1996;7(4):321-330.

(103) Breuer R, Lossos IS, Or R, Krymsky M, Dagan A, Yedgar S. Abatement of bleomycin-induced pulmonary injury by cell-impermeable inhibitor of phospholipase A2. Life Sci 1995;57(16):PL237-PL240.

(104) Chen S, Gavish B, Zhang S, Mahler Y, Yedgar S. Monitoring of erythrocyte aggregate morphology under flow by computerized image analysis. Biorheology 1995;32(4):487-496.

(105) Yedgar S, Tetreau C, Gavish B, Lavalette D. Viscosity dependence of O2 escape from respiratory proteins as a function of cosolvent molecular weight. Biophys J 1995;68(2):665-670.

(106) Yedgar S, Dan P, Dagan A, Ginsburg I, Lossos IS, Breuer R. Control of inflammatory processes by cell-impermeable inhibitors of phospholipase A2. Agents Actions 1995;46(SUPPL.):77-84.

(107) Barshtein G, Almagor A, Yedgar S, Gavish B. Inhomogeneity of viscous aqueous solutions. Physical Review E 1995;52(1):555-557.

(108) Chen S, Gavish B, Barshtein G, Mahler Y, Yedgar S. Red blood cell aggregability is enhanced by physiological levels of hydrostatic pressure. Biochim Biophys Acta Biomembr 1994;1192(2):247-252.

(109) Chen S, Barshtein G, Gavish B, Mahler Y, Yedgar S. Monitoring of red blood cell aggregability in a flow-chamber by computerized image analysis. Clin Hemorheol Microcirc 1994;14(4):497-508.

(110) Reisfeld N, Yedgar S. Inhibition of ldl-associated phospholipase a activity in human plasma by albumin. J Basic Clin Physiol Pharmacol 1994;5(2):107-116.

(111) Reisfeld N, Lichtenberg D, Dagan A, Yedgar S. Apolipoprotein B exhibits phospholipase A1 and phospholipase A2 activities. FEBS Lett 1993;315(3):267-270.

(112) Meyuhas D, Yedgar S, Rotenberg M, Reisfeld N, Lichtenberg D. The use of C6-NBD-PC for assaying phospholipase A2-activity: Scope and limitations. Biochim Biophys Acta Lipids Lipid Metab 1992;1124(3):223-232.

(113) Lidan D, Yedgar S, Aronson HB, Sohmer H. Influence of experimentally elevated blood viscosity on the auditory nerve-brainstem evoked response and threshold. Hear Res 1992;62(1):57-62.

(114) Goping G, Yedgar S, Pollard HB, Kuijpers GAJ. Flat embedding and immunolabelling of SW 1116 colon carcinoma cells in LR white: An improved technique in light and electron microscopy. Microsc Res Tech 1992;21(1):1-9.

(115) Almagor A, Yedgar S, Gavish B. Viscous cosolvent effect on the ultrasonic absorption of bovine serum albumin. Biophys J 1992;61(2):480-486.

(116) Yedgar S, Eidelman O, Malden E, Roberts D, Etcheberrigaray R, Goping G, et al. Cyclic AMP-independent secretion of mucin by SW1116 human colon carcinoma cells. Differential control by Ca2+ ionophore A23187 and arachidonic acid. Biochem J 1992;283(2):421-426.

(117) Bennett ER, Yedgar S, Lerer B, Ebstein RP. Phospholipase A2 activity in Epstein-Barr virus-transformed lymphoblast cells from schizophrenic patients. Biol Psychiatry 1991;29(11):1058-1062.

(118) Feitelson J, Yedgar S. The effect of the solvent viscosity on the migration of small molecules through the structure of myoglobin. Biorheology 1991;28(1-2):99-105.

(119) Almagor A, Yedgar S, Gavish B. Seventh International Congress of Biorheology, Nancy, France, 18-23 June 1989. Symposium: The role of fluid viscosity in cellular and biochemical processes. Solvent viscosity effects on protein dynamics studied by ultrasonic absorption. Biorheology 1990;27(3-4):605-610.

(120) Yedgar S, Vlodavsky I, Panet A, Reisfeld N, Eldor A. Interferon enhances phospholipase A2 activity in bovine aortic endothelial cells. Eicosanoids 1990;3(4):225-229.

(121) Etcheberrigaray R, Yedgar S, Rojas E, Pollard HB. Multiple potassium and chloride channels in the human colon carcinoma cell line SW1116. Mol Membr Biol 1990;9(3):215-225.

(122) Yedgar S, Reisfeld N. Seventh International Congress of Biorheology, Nancy, France, 18-23 June 1989. Symposium: The role of fluid viscosity in cellular and biochemical processes. Regulation of cell membrane function and secretion by extracellular fluid viscosity. Biorheology 1990;27(3-4):581-588.

(123) Ebstein RP, Bennett ER, Hadjez J, Silver H, Yedgar S, Lerer B. Cyclic AMP second messenger signal generation in EBV-transformed lymphoblastoid cells from schizophrenic patients. J Psychiatr Res 1990;24(2):121-127.

(124) Shohami E, Shapira Y, Yadid G, Reisfeld N, Yedgar S. Brain Phospholipase A2 Is Activated After Experimental Closed Head Injury in the Rat. J Neurochem 1989;53(5):1541-1546.

(125) BRENNER T, YEDGAR S, WEIDENFELD J, ABRAMSKY O. Phospholipase A2 Activity in Cultured Glial Cells Correlation with Appearance of Myelin Markers and Effects of Steroid Hormones. Ann New York Acad Sci 1988;540(1):403-404.

(126) Mayer M, Yedgar S, Hurwitz A, Palti Z, Finzi Z, Milwidsky A. Effect of viscous macromolecules on peritoneal plasminogen activator activity: A potential mechanism for their ability to reduce postoperative adhesion formation. Am J Obstet Gynecol 1988;159(4):957-963.

(127) Halle D, Yedgar S. Mild pressure induces resistance of erythrocytes to hemolysis by snake venom phospholipase A2. Biophys J 1988;54(3):393-396.

(128) Yedgar S, Reisfeld N, Halle D, Yuli I. Medium Viscosity Regulates the Activity of Membrane-Bound and Soluble Phospholipase A2. Biochemistry 1987;26(12):3395-3401.

(129) Hovav E, Halle D, Yedgar S. Viscous macromolecules inhibit erythrocyte hemolysis induced by snake venom phospholipase A2. Biorheology 1987;24(4):377-384.

(130) Dagan A, Yedgar S. A facile method for direct determination of phospholipase A2 activity in intact cells. Biochem Int 1987;15(4):801-808.

(131) Yedgar S, Reisfeld-Granot N, Sela B-. Regulation of liver cell ganglioside composition by extracellular fluid viscosity. Lipids 1986;21(10):629-633.

(132) Yedgar S, Reisfeld N, Dagan A. Synthesis of cell-impermeable inhibitor of phospholipase A2. FEBS Lett 1986;200(1):165-168.

(133) Yedgar S, Sela B-. Alterations in gangliosides of rat liver cells in hyperlipidemic state. J Biochem 1985;98(3):673-680.

(134) Yedgar S, Eilam O, Shafrir E. Regulation of plasma lipid levels by plasma viscosity in nephrotic rats. Am J Physiol Endocrinol Metab 1985;11(1):E10-E14.

(135) Yedgar S, Cooper GV. Organization and structure of two mixed micellar phases of the sphingomyelin/Triton X-305 system. Arch Biochem Biophys 1985;240(1):191-200.

(136) Yedgar S, Carew TE, Pittman RC. Tissue sites of catabolism of albumin in rabbits. Am J Physiol Endocrinol Metab 1983;7(1):E101-E107.

(137) Yedgar S, Weinstein DB, Patsch W, Schonfeld G, Casanada FE, Steinberg D. Viscosity of culture medium as a regulator of synthesis and secretion of very low density lipoproteins by cultured hepatocytes. J Biol Chem 1982;257(5):2188-2192.

(138) Yedgar S, Cohen R, Gatt S, Barenholz Y. Hydrolysis of monomolecular layers of synthetic sphingomyelins by sphingomyelinase of staphylococcus aureus. Biochem J 1982;201(3):597-603.

(139) Mayer M, Yedgar S, Joffe M, Shafrir E. Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity. Nephron 1981;29(5-6):223-228.

(140) Yedgar S, Gatt S. Enzymic hydrolysis of sphingomyelin in the presence of bile salts. Biochem J 1980;185(3):749-754.

(141) Lichtenberg D, Yedgar S, Cooper G, Gatt S. Studies on the Molecular Packing of Mixed Dispersions of Triton X-100 and Sphingomyelin and Its Dependence on Temperature and Cloud Point. Biochemistry 1979;18(12):2574-2582.

(142) Gatt S, Dinur T, Yedgar S, Leibovitz-Ben Gershon Z. Effect of detergents on the utilization of sphingomyelin by brain sphingomyelinases. Adv Exp Med Biol 1978;101:487-500.

(143) Yedgar S, Gatt S. Effect of Triton X-100 on the Hydrolysis of Sphingomyelin by Sphingomyelinase of Rat Brain. Biochemistry 1976;15(12):2570-2573.

(144) Yedgar S, Gatt S. Proceedings: Kinetic aspects of the stimulation of enzymatic hydrolysis of sphingomyelin by triton x-100. Isr J Med Sci 1975;11(11):1172.

(145) Yedgar S, Barenholz Y, Cooper VG. Molecular weight, shape and structure of mixed micelles of Triton X-100 and sphingomyelin. Biochim Biophys Acta Biomembr 1974;363(1):98-111.

(146) Cooper VG, Yedgar S, Barenholz Y. Diffusion coefficients of mixed micelles of Triton X-100 and sphingomyelin and of sonicated sphingomyelin liposomes, measured by autocorrelation spectroscopy of Rayleigh scattered light. Biochim Biophys Acta Biomembr 1974;363(1):86-97.

(147) Yedgar S, Hertz R, Gatt S. Solubilization of sphingomyelin by triton X-100 effect of the method of mixing and the concentrations of detergent and lipid. Chem Phys Lipids 1974;13(4):404-414.