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The Faculty of Medicine - Biochemistry and Molecular Biology: Rahamimoff Hannah


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Rahamimoff H, Elbaz B, Valitsky M, Khatib M, Eskin-Schwartz M, Elmaz D. Immunosuppressive drugs, immunophilins, and functional expression of NCX isoforms. Adv Exp Med Biol 2013;961:275-287.

(2) Elbaz B, Valitsky M, Davidov G, Rahamimoff H. Cyclophilin A is involved in functional expression of the Na +-Ca2+ exchanger NCX1. Biochemistry 2010;49(35):7634-7642.

(3) Elbaz B, Alperovitch A, Gottesman MM, Kimchi-Sarfaty C, Rahamimoff H. Modulation of Na+-Ca2+ exchanger expression by immunosuppressive drugs is isoform-specific. Mol Pharmacol 2008;73(4):1254-1263.

(4) Rahamimoff H, Elbaz B, Alperovich A, Kimchi-Sarfaty C, Gottesman MM, Lichtenstein Y, et al. Cyclosporin A-dependent downregulation of the Na+/Ca 2+ exchanger expression. Ann New York Acad Sci 2007;1099:204-214.

(5) Rahamimoff H, Alperovitz A, Kimchi-Sarfaty C, Elbaz B, Kasir J. Can cyclosporin A (CsA) - Dependent down regulation of the Na +-Ca2+ exchanger provide an explanation for the drug related clinical complications? Auton Autacoid Pharmacol 2006;26(1):70.

(6) Kimchi-Sarfaty C, Kasir J, Ambudkar SV, Rahamimoff H. Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833. J Biol Chem 2002;277(4):2505-2510.

(7) Ren X, Kasir J, Rahamimoff H. Cysteine residues are important for functional expression of the Na+/Ca2+ exchanger NCX1 in HEK 293 cells. Ann New York Acad Sci 2002;976:89.

(8) Rahamimoff H, Ren X, Kimchi-Sarfaty C, Ambudkar S, Kasir J. NCX1 surface expression: A tool to identify structural elements of functional importance. Ann New York Acad Sci 2002;976:176-186.

(9) Ren X, Kasir J, Rahamimoff H. The Transport Activity of the Na+-Ca2+ Exchanger NCX1 Expressed in HEK 293 Cells is Sensitive to Covalent Modification of Intracellular Cysteine Residues by Sulfhydryl Reagents. J Biol Chem 2001;276(12):9572-9579.

(10) Kasir J, Ren X, Furman I, Rahamimoff H. Truncation of the C terminus of the rat brain Na+-Ca2+ exchanger RBE- 1 (NCX1.4) impairs surface expression of the protein. J Biol Chem 1999;274(35):24873-24880.

(11) Cook O, Low W, Rahamimoff H. Membrane topology of the rat brain Na+-Ca2+ exchanger. Biochim Biophys Acta Biomembr 1998;1371(1):40-52.

(12) Rahamimoff H, Low W, Cook O, Furman I, Kasir J, Vatashski R. The structural basis of Na+-Ca2+ exchange activity. Ann New York Acad Sci 1996;779:29-36.

(13) Furman I, Cook O, Kasir J, Low W, Rahamimoff H. The putative ammo-terminal signal peptide of the cloned rat brain Na+-Ca2+ exchanger gene (RBE-1) is not mandatory for functional expression. J Biol Chem 1995;270(32):19120-19127.

(14) Furman I, Cook O, Kasir J, Rahamimoff H. Cloning of two isoforms of the rat brain Na+Ca+ exchanger gene and their functional expression in HeLa cells. FEBS Lett 1993;319(1-2):105-109.

(15) Low W, Kasir J, Rahamimoff H. Cloning of the rat heart Na+ -Ca2+ exchanger and its functional expression in HeLa cells. FEBS Lett 1993;316(1):63-67.

(16) Low W, Brawarnick N, Rahamimoff H. The inhibitory effect of Mn2+ on the ATP-dependent Ca2+ pump in rat brain synaptic plasma membrane vesicles. Biochem Pharmacol 1991;42(8):1537-1543.

(17) Dahan D, Spanier R, Rahamimoff H. The modulation of rat brain Na+-Ca2+ exchange by K+. J Biol Chem 1991;266(4):2067-2075.

(18) Tessari M, Rahamimoff H. Na+-Ca2+ exchange activity in synaptic plasma membranes derived from the electric organ of Torpedo ocellata. Biochim Biophys Acta Biomembr 1991;1066(2):208-218.

(19) RAHAMIMOFF H, DAHAN D, FURMAN I, SPANIER R, TESSARI M. Molecular and Mechanistic Heterogeneity of the Na+ ‐ Ca2+ Exchanger. Ann New York Acad Sci 1991;639(1):210-221.

(20) Furman I, Rahamimoff H. The expression of rat brain synaptic plasma membrane Na+-Ca2+ exchange activity in Xenopus oocytes. Brain Res 1990;532(1-2):41-46.

(21) Hermoni-Levine M, Rahamimoff H. Role of the Phospholipid Environment in Modulating the Activity of the Rat Brain Synaptic Plasma Membrane Ca2+-ATPase. Biochemistry 1990;29(20):4940-4950.

(22) Rahamimoff H. Na+–Ca2+ exchanger: The elusive protein. Curr Top Cell Regul 1990;31(C):241-271.

(23) Barzilai A, Spanier R, Rahamimoff H. Immunological identification of the synaptic plasma membrane Na+-Ca2+ exchanger. J Biol Chem 1987;262(21):10315-10320.

(24) Erdreich A, Rahamimoff H. The possible involvement of the phospholipid phase of membranes in mediating the effects of verapamil on Ca2+ transport. Biochem Pharmacol 1987;36(11):1775-1780.

(25) Barzilai A, Rahamimoff H. Stoichiometry of the Sodium-Calcium Exchanger in Nerve Terminals. Biochemistry 1987;26(19):6113-6118.

(26) Hermoni M, Barzilai A, Rahamimoff H. Modulation of the Na+-Ca+ antiport by its ionic environment: The effect of lithium. Isr J Med Sci 1987;23(1-2):44-48.

(27) Barzilai A, Rahamimoff H. Studies on the mechanism of action of purified and reconsititued Na+-Ca2+ exchanger from nerve terminals. J Basic Clin Physiol Pharmacol 1986;6(Supplement):7-14.

(28) Erdreich A, Rahamimoff H. The inhibition of Ca uptake in cardiac membrane vesicles by verapamil. Biochem Pharmacol 1984;33(14):2315-2323.

(29) Rahamimoff H, Spanier R. The asymmetric effect of lanthanides on Na+-gradient-dependent Ca2+ transport in synaptic plasma membrane vesicles. Biochim Biophys Acta Biomembr 1984;773(2):279-289.

(30) Papazian DM, Rahamimoff H, Goldin SM. Partial purification and functional identification of a calmodulin-activated, adenosine 5'-triphosphate-dependent calcium pump from synaptic plasma membranes. J Neurosci 1984;4(8):1933-1943.

(31) Barzilai A, Spanier R, Rahamimoff H. Isolation, purification, and reconstitution of the Na+ gradient-dependent Ca2+ transporter (Na+-Ca2+ exchanger) from brain synaptic plasma membranes. Proc Natl Acad Sci U S A 1984;81(20 I):6521-6525.

(32) Ramu A, Spanier R, Rahamimoff H, Fuks Z. Restoration of doxorubicin responsiveness in doxorubicin-resistant p388 murine leukaemia cells. Br J Cancer 1984;50(4):501-507.

(33) Chan SY, Hess EJ, Rahamimoff H, Goldin SM. Purification and immunological characterization of a calcium pump from bovine brain synaptosomal vesicles. J Neurosci 1984;4(6):1468-1478.

(34) Erdreich A, Spanier R, Rahamimoff H. The inhibition of Na-dependent Ca uptake by verapamil in synaptic plasma membrane vesicles. Eur J Pharmacol 1983;90(2-3):193-202.

(35) Barzilai A, Rahamimoff H. Inhibition of Ca2+-transport ATPase from synaptosomal vesicles by flavonoids. Biochim Biophys Acta Biomembr 1983;730(2):245-254.

(36) Goldin SM, Chan SY, Papazian DM, Hess EJ, Rahamimoff H. Purification and characterization of ATP-dependent calcium pumps from synaptosomes. Cold Spring Harb Symp Quant Biol 1983;48 Pt 1:287-295.

(37) Barzilai A, Rahamimoff H. Studies on the mechanism of action of quercetin and other flavones on calcium transport systems in nerve terminals. Isr J Med Sci 1982;18(6):2.

(38) Rahamimoff H, Abramovitz E, Papazian D, Goldin SM, Spanier R. Calcium transport systems in nerve terminals. Studies on membrane vesicles. J PHYSIOL 1980;76(5):487-495.

(39) Rahamimoff R, Lev-Tov A, Meiri H, Rahamimoff H, Nussinovitch I. Regulation of acetylcholine liberation from presynaptic nerve terminals. Monogr Neural Sci 1980;7:3-18.

(40) Rahamimoff H, Spanier R. Sodium-dependent calcium uptake in membrane vesicles derived from rat brain synaptosomes. FEBS Lett 1979;104(1):111-114.

(41) Papazian D, Rahamimoff H, Goldin SM. Reconstitution and purification by 'transport specificity fractionation' of an ATP-dependent calcium transport component from synaptosome-derived vesicles. Proc Natl Acad Sci U S A 1979;76(8):3708-3712.

(42) Binah O, Meiri U, Rahamimoff H. The effects of HgCl2 and mersalyl on mechanisms regulating intracellular calcium and transmitter release. Eur J Pharmacol 1978;51(4):453-457.

(43) Rahamimoff H, Abramovitz E. Ca transport and ATPase activity of synaptosomal vesicles from rat brain. FEBS Lett 1978;92(2):163-167.

(44) Rahamimoff H, Abramovitz E. Calcium transport in a vesicular membrane preparation from rat brain synaptosomes. FEBS Lett 1978;89(2):223-226.

(45) Rahamimoff R, Erulkar SD, Alnaes E, Meiri H, Rotshenker S, Rahamimoff H. Modulation of transmitter release by calcium ions and nerve impulses. Cold Spring Harb Symp Quant Biol 1976;40:107-116.

(46) Alnaes E, Meiri U, Rahamimoff H, Rahamimoff R. Proceedings: Possible role of mitochondria in transmitter release. J Physiol 1974;241(1):30P-31P.

(47) Rahamimoff H, Baksht E, Lapidot Y, de Groot N. The binding of Phe-tRNAPhe and gly2Phe-tRNAPhe to reticulocyte ribosomal peptidyl sites by a mechanism not involving translocation. FEBS Lett 1972;22(2):249-251.