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The Faculty of Medicine - Developmental Biology and Cancer Research: Ben-Sasson Shmuel (Muli)


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Lei R, Hou J, Chen Q, Yuan W, Cheng B, Sun Y, et al. Self-Assembling Myristoylated Human α-Defensin 5 as a Next-Generation Nanobiotics Potentiates Therapeutic Efficacy in Bacterial Infection. ACS Nano 2018;12(6):5284-5296.

(2) Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, et al. Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals. Dev Cell 2018;45(6):726-737.e3.

(3) Hou J, Chen Q, Wu X, Zhao D, Reuveni H, Licht T, et al. S1PR3 signaling drives bacterial killing and is required for survival in bacterial sepsis. Am J Respir Crit Care Med 2017;196(12):1559-1570.

(4) Ben-Yehuda Greenwald M, Frušić-Zlotkin M, Soroka Y, Ben-Sasson S, Bianco-Peled H, Kohen R. A novel role of topical iodine in skin: Activation of the Nrf2 pathway. Free Radic Biol Med 2017;104:238-248.

(5) Ben Yehuda Greenwald M, Frušić-Zlotkin M, Soroka Y, Ben Sasson S, Bitton R, Bianco-Peled H, et al. Curcumin Protects Skin against UVB-Induced Cytotoxicity via the Keap1-Nrf2 Pathway: The Use of a Microemulsion Delivery System. Oxidative Med Cell Longevity 2017;2017.

(6) Greenwald MB-, Ben-Sasson S, Bianco-Peled H, Kohen R. Skin redox balance maintenance: The need for an Nrf2-activator delivery system. Cosmetics 2016;3(1).

(7) Ben Yehuda Greenwald M, Anzi S, Ben Sasson S, Bianco-Peled H, Kohen R. Can nitroxides evoke the Keap1-Nrf2-ARE pathway in skin? Free Radic Biol Med 2014;77:258-269.

(8) Ben Yehuda Greenwald M, Ben Sasson S, Bianco-Peled H. A new method for encapsulating hydrophobic compounds within cationic polymeric nanoparticles. J Microencapsulation 2013;30(6):580-588.

(9) Leshem O, Madar S, Kogan-Sakin I, Kamer I, Goldstein I, Brosh R, et al. TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model. PLoS ONE 2011;6(7).

(10) Ben-Sasson SA, Grover NB. Erratum: Osmosis: A macroscopic phenomenon, a microscopic view (American Journal of Physiology - Advances in Physiology Education (2003) 27, (15-19)). Am J Physiol Adv Physiol Educ 2007;31(2):245.

(11) Riss J, Khanna C, Koo S, Chandramouli GVR, Yang HH, Hu Y, et al. Cancers as wounds that do not heal: Differences and similarities between renal regeneration/repair and renal cell carcinoma. Cancer Res 2006;66(14):7216-7224.

(12) Strehblow C, Sperker W, Hevesi A, Garamvölgyi R, Petrasi Z, Shirazi M, et al. Paradoxical effects of aurintricarboxylic acid and RG-13577: Acute thrombosis and in-stent stenosis in a passive-coated stent. J Endovasc Ther 2006;13(1):94-103.

(13) Goldenberg-Furmanov M, Stein I, Pikarsky E, Rubin H, Kasem S, Wygoda M, et al. Lyn Is a Target Gene for Prostate Cancer: Sequence-Based Inhibition Induces Regression of Human Tumor Xenografts. Cancer Res 2004;64(3):1058-1066.

(14) Niv MY, Rubin H, Cohen J, Tsirulnikov L, Licht T, Peretzman-Shemer A, et al. Sequence-based Design of Kinase Inhibitors Applicable for Therapeutics and Target Identification. J Biol Chem 2004;279(2):1242-1255.

(15) Anis Y, Leshem O, Reuveni H, Wexler I, Ben Sasson R, Yahalom B, et al. Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes. Diabetologia 2004;47(7):1232-1244.

(16) Licht T, Tsirulnikov L, Reuveni H, Yarnitzky T, Ben-Sasson SA. Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3). Blood 2003;102(6):2099-2107.

(17) Irony-Tur-Sinai M, Vlodavsky I, Ben-Sasson SA, Pinto F, Sicsic C, Brenner T. A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation. J Neurol Sci 2003;206(1):49-57.

(18) Ben-Sasson SA, Grover NB. Osmosis: A macroscopic phenomenon, a microscopic view. Am J Physiol Adv Physiol Educ 2003;27(1-4):15-19.

(19) Shargal Y, Viola N, Nagler A, Merin G, Schmidt A, Buddecke E, et al. Inhibition of anastomotic intimal hyperplasia by a synthetic nonsulphated heparin-mimicking compound. Exp Clin Cardiol 2002;7(2-3):73-79.

(20) Benezra M, Ishai-Michaeli R, Ben-Sasson SA, Vlodavsky I. Structure-activity relationships of heparin-mimicking compounds in induction of bFGF release from extracellular matrix and inhibition of smooth muscle cell proliferation and heparanase activity. J Cell Physiol 2002;192(3):276-285.

(21) Strehblow C, Gyöngyösi M, Sperker W, Shirazi M, Windberger U, Pugatsch T, et al. Usefulness of intravascular ultrasound-guided histological measurements after stenting in porcine coronary artery. Coron Artery Dis 2002;13(5):291-294.

(22) Shih I-, Wang T-, Traverso G, Romans K, Hamilton SR, Ben-Sasson S, et al. Top-down morphogenesis of colorectal tumors. Proc Natl Acad Sci U S A 2001;98(5):2640-2645.

(23) Keshet E, Ben-Sasson SA. Anticancer drug targets: Approaching angiogenesis. J Clin Invest 1999;104(11):1497-1501.

(24) Weingärtner K, Ben-Sasson SA, Stewart R, Richie JP, Riedmiller H, Folkman J. Endothelial cell proliferation activity in benign prostatic hyperplasia and prostate cancer: An in vitro model for assessment. J Urol 1998;159(2):465-470.

(25) Katz A, Vlodavsky I, Davies M, Miao H-, Ben-Sasson SA, Darmon D, et al. Antiproliferative activity to glomerular mesangial cells and receptor binding of a heparin-mimicking polyaromatic anionic compound. J Am Soc Nephrol 1997;8(11):1688-1697.

(26) Miao H-, Ornitz DM, Aingorn E, Ben-Sasson SA, Vlodavsky I. Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound. J Clin Invest 1997;99(7):1565-1575.

(27) Nadir E, Margalit H, Gallily T, Ben-Sasson SA. Microsatellite spreading in the human genome: Evolutionary mechanisms and structural implications. Proc Natl Acad Sci U S A 1996;93(13):6470-6475.

(28) Ben-Sasson SA, Sherman Y, Gavrieli Y. Identification of Dying Cells—In Situ Staining. Methods Cell Biol 1995;46(C):29-39.

(29) Beller U, Haimovitch R, Ben-Sasson S. Periovulatory multifocal mesothelial proliferation: A possible association with malignant transformation. Int J Gynecol Cancer 1995;5(4):306-309.

(30) Beeri R, Symon Z, Brezis M, Ben-Sasson SA, Baehr PH, Rosen S, et al. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int 1995;47(6):1806-1810.

(31) Vlodavsky I, Miao H-, Atzmon R, Levi E, Zimmermann J, Bar-Shavit R, et al. Control of cell proliferation by heparan sulfate and heparin-binding growth factors. Thromb Haemost 1995;74(1):534-540.

(32) Margalit H, Nadir E, Ben-Sasson SA. A complete Alu element within the coding sequence of a central gene. Cell 1994;78(2):173-174.

(33) Benezra M, Ben-Sasson SA, Regan J, Chang M, Bar-Shavit R, Vlodavsky I. Antiproliferative activity to vascular smooth muscle cells and receptor binding of heparin-mimicking polyaromatic anionic compounds. Arterioscler Thromb Vasc Biol 1994;14(12):1992-1999.

(34) BEN‐SASSON SA, FINESTONE A, MOSKOWITZ M, MARON R, WEINNER M, LEICHTER I, et al. Extended duration of vertical position might impair bone metabolism. Eur J Clin Invest 1994;24(6):421-425.

(35) Davis DL, Ben-Sasson S, Antognini JF, Kassirer JP. Do Medical Journals Suppress Information? New Engl J Med 1993;328(7):510-511.

(36) Margalit H, Fischer N, Ben-Sasson SA. Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues. J Biol Chem 1993;268(26):19228-19231.

(37) Gabizon R, Meiner Z, Halimi M, Ben‐Sasson SA. Heparin‐like molecules bind differentially to prion‐proteins and change their intracellular metabolic fate. J Cell Physiol 1993;157(2):319-325.

(38) Arad-Dann H, Beller U, Haimovitch R, Gavrieli Y, Ben-Sasson SA. Immunohistochemistry of phosphotyrosine residues: Identification of distinct intracellular patterns in epithelial and steroidogenic tissues. J Histochem Cytochem 1993;41(4):513-519.

(39) Regan JR, Bruno JG, Chang MN, Sabatino R, D'alisa R, Ben-Sasson SA, et al. Mimicry of Biological Macromolecules by Polyaromatic Anionic Compounds. J Bioact Compat Polym 1993;8(4):317-337.

(40) Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119(3):493-501.

(41) Ben-Sasson SA, Davis DL. The authors' reply. Cancer Causes Control 1992;3(6):582.

(42) Ben-Sasson SA, Davis DL. Neonatal exposure to protoporphyrin-activating lighting as a contributing cause of childhood acute lymphocytic leukemia. Cancer Causes Control 1992;3(4):383-387.

(43) Benezra M, Vlodavsky I, Ben-Sasson S. Reversal of Basic Fibroblast Growth Factor-mediated Autocrine Cell Transformation by Aromatic Anionic Compounds. Cancer Res 1992;52(20):5656-5662.

(44) Morecki S, Slavin S, Ben-Sasson SA. Selective abrogation of alloreactivity via priming in the presence of aphidicolin, a specific inhibitor of DNA polymerase. J Immunol 1989;143(3):838-843.

(45) Ben-Chetrit E, Eilat D, Ben-Sasson SA. Specific inhibition of the DNA-anti-DNA immune reaction by low molecular weight anionic compounds. Immunology 1988;65(3):479-485.

(46) Ben-Sasson SA, Cohen T, Voss R. Background allelic variants in normal hemopoietic cells and Bloom's syndrome erythrocytes and the possible implication of somatic crossingover. Cancer Genet Cytogenet 1985;15(3-4):237-242.

(47) Ben-Sasson SA, Henkart PA. Generation of selective microenvironment at the cell periphery through bulk-phase hydrophilic polymers. Biochim Biophys Acta Mol Cell Res 1983;763(2):99-106.

(48) Grover NB, Ben Sasson SA, Naaman J. Electrical sizing of particles in suspensions. V. High electric fields. Anal Quant Cytol 1982;4(4):302-308.

(49) Ben Sasson SA, Naaman J, Grover NB. Membrane changes induced by high electric fields. Evidence for sulfhydryl group involvement. Anal Quant Cytol 1982;4(4):309-314.

(50) Hamburger J, Ben-Sasson SA. Serobiological differentiation between antischistosomal (Schistosoma mansoni) antisera. Tropenmed Parasitol 1981;32(1):43-47.

(51) Ben-Sasson SA. Immunoglobulin differentiation is dictated by repeated recombination sequences within the V region prototype gene: A hypothesis. Proc Natl Acad Sci U S A 1979;76(9):4598-4602.

(52) Laufer N, Grover NB, Ben-Sasson S, Freund H. Effects of adenosine diphosphate, colchicine and temperature on size of human platelets. Thromb Haemost 1979;41(3):491-497.

(53) Ben Sasson SA, Henkart PA. Enhancement of weak mixed lymphocyte type reactions by hydrophilic polymers. J Immunol 1977;119(1):227-231.

(54) Ben-Sasson S, Shaviv R, Bentwich Z, Slavin S, Doljanski F. Osmotic behavior of normal and leukemic lymphocytes. Blood 1975;46(6):891-899.

(55) Doljanski F, Ben‐Sasson S, Reich M, Grover NB. Dynamic osmotic behavior of chick blood lymphocytes. J Cell Physiol 1974;84(2):215-223.

(56) Ben‐Sasson S, Patinkin D, Grover NB, Doljanski F. Electrical sizing of particles in suspensions IV. Lymphocytes. J Cell Physiol 1974;84(2):205-214.

(57) Grover NB, Naaman J, Ben-Sasson S, Doljanski F. Electrical Sizing of Particles in Suspensions: III. Rigid Spheroids and Red Blood Cells. Biophys J 1972;12(9):1099-1116.

(58) Grover NB, Naaman J, Ben-Sasson S, Doljanski F. Electrical Sizing of Particles in Suspensions: I. Theory. Biophys J 1969;9(11):1398-1414.

(59) Grover NB, Naaman J, Ben-Sasson S, Doljanski F, Nadav E. Electrical Sizing of Particles in Suspensions: II. Experiments with Rigid Spheres. Biophys J 1969;9(11):1415-1425.