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School of Public Health: Friedlander Yechiel

Researchers / חוקרים

 Last updated June 2021 - School of Public Health

List of Publications

(1) Chang X, Gurung RL, Wang L, Jin A, Li Z, Wang R, et al. Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population. Commun Biolog 2021;4(1).

(2) Savitsky B, Manor O, Lawrence G, Friedlander Y, Siscovick DS, Hochner H. Environmental mismatch and obesity in humans: The Jerusalem Perinatal Family Follow-Up Study. Int J Obes 2021.

(3) Dior UP, Karavani G, Bursztyn M, Paltiel O, Calderon-Margalit R, Friedlander Y, et al. Birth Weight and Maternal Body Size as Determinants of Blood Pressure at Age 17: Results from the Jerusalem Perinatal Study Cohort. Matern Child Health J 2021;25(1):162-171.

(4) Chang X, Wang L, Guan SP, Kennedy BK, Liu J, Khor C-, et al. The association of genetically determined serum glycine with cardiovascular risk in East Asians. Nutr Metab Cardiovasc Dis 2021.

(5) Chang X, Dorajoo R, Sun Y, Wang L, Ong CN, Liu J, et al. Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population. Nutr J 2020;19(1).

(6) West RK, Livny A, Ravona-Springer R, Bendlin BB, Heymann A, Leroith D, et al. Higher BMI is associated with smaller regional brain volume in older adults with type 2 diabetes. Diabetologia 2020;63(11):2446-2451.

(7) Chang X, Dorajoo R, Han Y, Wang L, Liu J, Khor C-, et al. Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population. Mol Genetics Genom Med 2020;8(10).

(8) Granot-Hershkovitz E, Wu P, Karasik D, Peter I, Peloso GM, Levy D, et al. Searching for parent-of-origin effects on cardiometabolic traits in imprinted genomic regions. Eur J Hum Genet 2020;28(5):646-655.

(9) Weisband YL, Manor O, Friedlander Y, Hochner H, Paltiel O, Calderon-Margalit R. Interpregnancy and interbirth intervals and all-cause, cardiovascular-related and cancer-related maternal mortality: Findings from a large population-based cohort study. J Epidemiol Community Health 2020.

(10) de las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, et al. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Mol Psychiatry 2020.

(11) Dorajoo R, Chang X, Gurung RL, Li Z, Wang L, Wang R, et al. Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies. Nat Commun 2019;10(1).

(12) Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nat Commun 2019;10(1).

(13) Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, et al. Associations of autozygosity with a broad range of human phenotypes. Nat Commun 2019;10(1).

(14) Sung YJ, De Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet 2019;28(15):2615-2633.

(15) Huang T, Wang T, Heianza Y, Wiggs J, Sun D, Choi H-, et al. Fish and marine fatty acids intakes, the FADS genotypes and long-term weight gain: A prospective cohort study. BMJ Open 2019;9(7).

(16) Malaspina D, Kranz T, Kleinhaus K, Daboul S, Rothman K, Gilman C, et al. Short duration of marriage at conception as an independent risk factor for schizophrenia. Schizophr Res 2019;208:190-195.

(17) De Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, et al. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Am J Epidemiol 2019;188(6):1033-1054.

(18) Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, et al. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 2019;51(6):957-972.

(19) Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, et al. Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nat Genet 2019;51(4):636-648.

(20) Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X, White I, et al. Equalization of four cardiovascular risk algorithms after systematic recalibration: Individual-participant meta-analysis of 86 prospective studies. Eur Heart J 2019;40(7):621-631.

(21) Bar-Meir M, Friedlander Y, Calderon-Margalit R, Hochner H. Mode of delivery and offspring adiposity in late adolescence: The modifying role of maternal pre-pregnancy body size. PLoS ONE 2019;14(1).

(22) Granot-Hershkovitz E, Karasik D, Friedlander Y, Rodriguez-Murillo L, Dorajoo R, Liu J, et al. A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Eur J Hum Genet 2018;26(12):1848-1858.

(23) Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nat Commun 2018;9(1).

(24) Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS ONE 2018;13(6).

(25) Simons LA, Simons J, Friedlander Y, McCallum J. LDL-cholesterol Predicts a First CHD Event in Senior Citizens, Especially So in Those With Elevated Lipoprotein(a): Dubbo Study of the Elderly. Heart Lung Circul 2018;27(3):386-389.

(26) Chang X, Dorajoo R, Sun Y, Han Y, Wang L, Khor C-, et al. Gene-diet interaction effects on BMI levels in the Singapore Chinese population. Nutr J 2018;17(1).

(27) Huang JY, Siscovick DS, Hochner H, Friedlander Y, Enquobahrie DA. Maternal gestational weight gain and DNA methylation in young women: Application of life course mediation methods. Epigenomics 2017;9(12):1559-1571.

(28) Lawrence GM, Friedlander Y, Calderon-Margalit R, Enquobahrie DA, Huang JY, Tracy RP, et al. Associations of social environment, socioeconomic position and social mobility with immune response in young adults: The Jerusalem Perinatal Family Follow-Up Study. BMJ Open 2017;7(12).

(29) Han Y, Dorajoo R, Chang X, Wang L, Khor C-, Sim X, et al. Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. Sci Rep 2017;7(1).

(30) Wheeler E, Leong A, Liu C-, Hivert M-, Strawbridge RJ, Podmore C, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med 2017;14(9).

(31) Spracklen CN, Chen P, Kim YJ, Wang X, Cai H, Li S, et al. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet 2017;26(9):1770-1784.

(32) Chang X, Chin H-, Quek S-, Goh DYT, Dorajoo R, Friedlander Y, et al. The genetic variation rs6903956 in the novel androgen-dependent tissue factor pathway inhibitor regulating protein (ADTRP) gene is not associated with levels of plasma coagulation factors in the Singaporean Chinese. Thromb J 2017;15(1).

(33) Manor O, Eisenbach Z, Israeli A, Friedlander Y. Mortality differentials among women: The Israel longitudinal mortality study. Israel's Destiny: Fertility and Mortality in a Divided Society; 2017. p. 281-302.

(34) Kark JD, Shemi G, Friedlander Y, Martin O, Manor O, Blondheim SH. Does religious observance promote health? mortality in secular vs. Religious kibbutzim in Israel. Israel's Destiny: Fertility and Mortality in a Divided Society; 2017. p. 243-256.

(35) Chang X, Salim A, Dorajoo R, Han Y, Khor C-, Van Dam RM, et al. Utility of genetic and non-genetic risk factors in predicting coronary heart disease in Singaporean Chinese. Eur J Prev Cardiol 2017;24(2):153-160.

(36) Huang JY, Gavin AR, Richardson TS, Rowhani-Rahbar A, Siscovick DS, Hochner H, et al. Accounting for Life-Course Exposures in Epigenetic Biomarker Association Studies: Early Life Socioeconomic Position, Candidate Gene DNA Methylation, and Adult Cardiometabolic Risk. Am J Epidemiol 2016;184(7):520-531.

(37) Ke T, Dorajoo R, Han Y, Khor C-, van Dam RM, Yuan J-, et al. Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population. Ann Hum Genet 2016;80(5):282-293.

(38) Savitsky B, Manor O, Friedlander Y, Burger A, Lawrence G, Calderon-Margalit R, et al. Associations of socioeconomic position in childhood and young adulthood with cardiometabolic risk factors: The Jerusalem Perinatal Family Follow-Up Study. J Epidemiol Community Health 2016;71(1):43-51.

(39) Lawrence GM, Siscovick DS, Calderon-Margalit R, Enquobahrie DA, Granot-Hershkovitz E, Harlap S, et al. Cohort profile: The jerusalem perinatal family follow-up study. Int J Epidemiol 2016;45(2):343-352.

(40) Paltiel O, Tajuddin SM, Polanker Y, Yazdgerdi S, Manor O, Friedlander Y, et al. Grand multiparity and reproductive cancer in the Jerusalem Perinatal Study Cohort. Cancer Causes Control 2016;27(2):237-247.

(41) Schorr L, Burger A, Hochner H, Calderon R, Manor O, Friedlander Y, et al. Mortality, cancer incidence, and survival in parents after bereavement. Ann Epidemiol 2016;26(2):115-121.

(42) Goldberg M, Calderon-Margalit R, Paltiel O, Abu Ahmad W, Friedlander Y, Harlap S, et al. Socioeconomic disparities in breast cancer incidence and survival among parous women: Findings from a population-based cohort, 1964-2008. BMC Cancer 2015;15(1).

(43) Dorajoo R, Sun Y, Han Y, Ke T, Burger A, Chang X, et al. A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population. Genes Nutr 2015;10(6):1-11.

(44) Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, et al. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat Genet 2015;47(11):1282-1293.

(45) White IR, Rapsomaniki E, Wannamethee SG, Morris RW, Willeit J, Willeit P, et al. Covariate-adjusted measures of discrimination for survival data. Biom J 2015;57(4):592-613.

(46) Han Y, Dorajoo R, Ke T, Ayala B, Chang X, Khor C-, et al. Interaction effects between Paraoxonase 1 variants and cigarette smoking on risk of coronary heart disease in a Singaporean Chinese population. Atherosclerosis 2015;240(1):40-45.

(47) Kranz TM, Harroch S, Manor O, Lichtenberg P, Friedlander Y, Seandel M, et al. De novo mutations from sporadic schizophrenia cases highlight important signaling genes in an independent sample. Schizophr Res 2015;166(1-3):119-124.

(48) Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 2015;518(7538):197-206.

(49) Moore A, Hochner H, Sitlani CM, Williams MA, Hoofnagle AN, De Boer IH, et al. Plasma vitamin D is associated with fasting insulin and homeostatic model assessment of insulin resistance in young adult males, but not females, of the Jerusalem Perinatal Study. Public Health Nutr 2015;18(7):1324-1331.

(50) Cheng C-, Yamashiro K, Jia Chen L, Ahn J, Huang L, Huang L, et al. New loci and coding variants confer risk for age-related macular degeneration in East Asians. Nat Commun 2015;6.

(51) Hochner H, Allard C, Granot-Hershkovitz E, Chen J, Sitlani CM, Sazdovska S, et al. Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults. PLoS Genet 2015;11(10).

(52) Lemaitre RN, King IB, Kabagambe EK, Wu JHY, McKnight B, Manichaikul A, et al. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res 2015;56(1):176-184.

(53) Cheng C-, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, et al. Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians. Nat Commun 2015;6.

(54) Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, et al. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet 2014;23(25):6961-6972.

(55) Dior UP, Lawrence GM, Sitlani C, Enquobahrie D, Manor O, Siscovick DS, et al. Parental smoking during pregnancy and offspring cardio-metabolic risk factors at ages 17 and 32. Atherosclerosis 2014;235(2):430-437.

(56) Wander PL, Hochner H, Sitlani CM, Enquobahrie DA, Lumley T, Lawrence GM, et al. Maternal genetic variation accounts in part for the associations of maternal size during pregnancy with offspring cardiometabolic risk in adulthood. PLoS ONE 2014;9(3).

(57) Gotkine M, Friedlander Y, Hochner H. Triathletes are over-represented in a population of patients with ALS. Amyotrophic Lateral Scler Frontotemporal Degener 2014;15(7-8):534-536.

(58) Schwartz I, Gartsman I, Adler B, Friedlander Y, Manor O, Levine H, et al. The association between post-polio symptoms as measured by the Index of Post-Polio Sequelae and self-reported functional status. J Neurol Sci 2014;345(1):87-91.

(59) Lawrence GM, Shulman S, Friedlander Y, Sitlani CM, Burger A, Savitsky B, et al. Associations of maternal pre-pregnancy and gestational body size with offspring longitudinal change in BMI. Obesity 2014;22(4):1165-1171.

(60) Chen P, Takeuchi F, Lee J-, Li H, Wu J-, Liang J, et al. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. Diabetes 2014;63(7):2551-2562.

(61) Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, et al. The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: A pooled analysis. PLoS ONE 2013;8(7).

(62) Dorajoo R, Li R, Ikram MK, Liu J, Froguel P, Lee J, et al. Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore? PLoS ONE 2013;8(7).

(63) Tayebi N, Ke T, Foo JN, Friedlander Y, Liu J, Heng C-. Association of single nucleotide polymorphism rs6903956 on chromosome 6p24.1 with coronary artery disease and lipid levels in different ethnic groups of the Singaporean population. Clin Biochem 2013;46(9):755-759.

(64) Kleinhaus K, Harlap S, Perrin M, Manor O, Margalit-Calderon R, Opler M, et al. Prenatal stress and affective disorders in a population birth cohort. Bipolar Disord 2013;15(1):92-99.

(65) Dior UP, Hochner H, Friedlander Y, Calderon-Margalit R, Jaffe D, Burger A, et al. Association between number of children and mortality of mothers: Results of a 37-year follow-up study. Ann Epidemiol 2013;23(1):13-18.

(66) Wormser D, Di Angelantonio E, Kaptoge S, Wood AM, Gao P, Sun Q, et al. Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: Individual participant meta-analysis. Int J Epidemiol 2012;41(5):1419-1433.

(67) Simons LA, Simons J, Friedlander Y, Mccallum J. Childbearing history and late-life mortality: The Dubbo study of Australian elderly. Age Ageing 2012;41(4):523-528.

(68) Hochner H, Friedlander Y, Calderon-Margalit R, Meiner V, Sagy Y, Avgil-Tsadok M, et al. Associations of maternal prepregnancy body mass index and gestational weight gain with adult offspring cardiometabolic risk factors: The jerusalem perinatal family follow-up study. Circulation 2012;125(11):1381-1389.

(69) Rapsomaniki E, White IR, Wood AM, Thompson SG, Tipping RW, Ford CE, et al. A framework for quantifying net benefits of alternative prognostic models. Stat Med 2012;31(2):114-130.

(70) Toperoff G, Aran D, Kark JD, Rosenberg M, Dubnikov T, Nissan B, et al. Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood. Hum Mol Genet 2012;21(2):371-383.

(71) Avgil Tsadok M, Friedlander Y, Paltiel O, Manor O, Meiner V, Hochner H, et al. Obesity and blood pressure in 17-Year-old offspring of mothers with gestational diabetes: Insights from the jerusalem perinatal study. Exp Dia Res 2011;2011.

(72) Simons LA, Simons J, Friedlander Y, Mccallum J. Predictors of long-term mortality in the elderly: The Dubbo Study. Intern Med J 2011;41(7):555-560.

(73) Lemaitre RN, Tanaka T, Tang W, Manichaikul A, Foy M, Kabagambe EK, et al. Genetic loci associated with plasma phospholipid N-3 fatty acids: A Meta-Analysis of Genome-Wide association studies from the charge consortium. PLoS Genet 2011;7(7).

(74) Erez G, Tirosh A, Rudich A, Meiner V, Schwarzfuchs D, Sharon N, et al. Phenotypic and genetic variation in leptin as determinants of weight regain. Int J Obes 2011;35(6):785-792.

(75) Simons LA, Simons J, Friedlander Y, McCallum J. Is Prediction of Cardiovascular Disease and All-cause Mortality Genuinely Driven by the Metabolic Syndrome, and Independently from its Component Variables? The Dubbo Study. Heart Lung Circul 2011;20(4):214-219.

(76) Tsadok MA, Friedlander Y, Paltiel O, Manor O, Meiner V, Hochner H, et al. Obesity and blood pressure in 17-year-old offspring of mothers with gestational diabetes: insights from the Jerusalem Perinatal Study. Exp Diabetes Res 2011;2011:906154.

(77) Assimes TL, Hlm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, et al. Lack of Association between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies. J Am Coll Cardiol 2010;56(19):1552-1563.

(78) Friedlander Y, Li G, Fornage M, Williams OD, Lewis CE, Schreiner P, et al. Candidate Molecular Pathway Genes Related to Appetite Regulatory Neural Network, Adipocyte Homeostasis and Obesity: Results from the CARDIA Study. Ann Hum Genet 2010;74(5):387-398.

(79) Lemaitre RN, King IB, Sotoodehnia N, Knopp RH, Mozaffarian D, McKnight B, et al. Endogenous red blood cell membrane fatty acids and sudden cardiac arrest. Metab Clin Exp 2010;59(7):1029-1034.

(80) Calderon-Margalit R, Schwartz SM, Wellons MF, Lewis CE, Daviglus ML, Schreiner PJ, et al. Prospective association of serum androgens and sex hormone-binding globulin with subclinical cardiovascular disease in young adult women: The "coronary artery risk development in young adults" women's study. J Clin Endocrinol Metab 2010;95(9):4424-4431.

(81) Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J, et al. Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol 2010;39(5):1345-1359.

(82) Sarwar N, Gao P, Kondapally Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies. Lancet 2010;375(9733):2215-2222.

(83) Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis. Lancet 2010;375(9709):132-140.

(84) Simons LA, Simons J, Friedlander Y, McCallum J. A Comparison of Risk Factors for Coronary Heart Disease and Ischaemic Stroke: The Dubbo Study of Australian Elderly. Heart Lung Circul 2009;18(5):330-333.

(85) Tipping RW, Ford CE, Simpson LM, Walldius G, Jungner I, Folsom AR, et al. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA 2009;302(4):412-423.

(86) Friedlander Y, Meiner V, Sharon N, Siscovick DS, Miserez AR. Leptin, insulin, and obesity-related phenotypes: Genetic influences on levels and longitudinal changes. Obesity 2009;17(7):1458-1460.

(87) Harlap S, Perrin MC, Deutsch L, Kleinhaus K, Fennig S, Nahon D, et al. Schizophrenia and birthplace of paternal and maternal grandfather in the Jerusalem perinatal cohort prospective study. Schizophr Res 2009;111(1-3):23-31.

(88) Calderon-Margalit R, Friedlander Y, Yanetz R, Kleinhaus K, Perrin MC, Manor O, et al. Cancer risk after exposure to treatments for ovulation induction. Am J Epidemiol 2009;169(3):365-375.

(89) Friedlander Y, Manor O, Paltiel O, Meiner V, Sharon N, Calderon R, et al. Birth Weight of Offspring, Maternal Pre-pregnancy Characteristics, and Mortality of Mothers: The Jerusalem Perinatal Study Cohort. Ann Epidemiol 2009;19(2):112-117.

(90) Dresner-Pollak R, Kinnar T, Friedlander Y, Sharon N, Rosenmann H, Pollak A. Estrogen receptor beta gene variant is associated with vascular dementia in elderly women. Genet Test Mol Biomarkers 2009;13(3):339-342.

(91) Calderon-Margalit R, Friedlander Y, Yanetz R, Deutsch L, Perrin MC, Kleinhaus K, et al. Preeclampsia and subsequent risk of cancer: update from the Jerusalem Perinatal Study. Am J Obstet Gynecol 2009;200(1):63.e1-63.e5.

(92) Durst R, Neumark Y, Meiner V, Friedlander Y, Sharon N, Polak A, et al. Increased risk for atherosclerosis of various macrophage scavenger receptor 1 alleles. Genet Test Mol Biomarkers 2009;13(5):583-587.

(93) Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009;41(3):334-341.

(94) Paltiel O, Yanetz R, Calderon-Margalit R, Manor O, Sharon N, Harlap S, et al. Very high birth weight of offspring is associated with an increased risk of leukemia in their mothers: Results of a population-based cohort study. Leuk Res 2008;32(11):1709-1714.

(95) Meiner V, Friedlander Y, Milo H, Sharon N, Ben-Avi L, Shpitzen S, et al. Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction. Ann Hum Genet 2008;72(6):732-741.

(96) Simons LA, Simons J, Friedlander Y, McCallum J. Usefulness of Fasting Plasma Glucose to Predict Mortality or Coronary Heart Disease in Persons ≥60 Years of Age Without Diabetes Mellitus or in Those With Undiagnosed Diabetes Mellitus (from The Dubbo Study). Am J Cardiol 2008;102(7):831-834.

(97) Kleinhaus K, Harlap S, Perrin MC, Manor O, Calderon-Margalit R, Friedlander Y, et al. Twin pregnancy and the risk of schizophrenia. Schizophr Res 2008;105(1-3):197-200.

(98) Malaspina D, Corcoran C, Kleinhaus KR, Perrin MC, Fennig S, Nahon D, et al. Acute maternal stress in pregnancy and schizophrenia in offspring: A cohort prospective study. BMC Psychiatry 2008;8.

(99) Harlap S, Kleinhaus K, Perrin MC, Calderon-Margalit R, Paltiel O, Deutsch L, et al. Consanguinity and birth defects in the jerusalem perinatal study cohort. Hum Hered 2008;66(3):180-189.

(100) Lemaitre RN, Siscovick DS, Berry EM, Kark JD, Friedlander Y. Familial aggregation of red blood cell membrane fatty acid composition: the Kibbutzim Family Study. Metab Clin Exp 2008;57(5):662-668.

(101) Perrin MC, Terry MB, Kleinhaus K, Deutsch L, Yanetz R, Tiram E, et al. Gestational diabetes and the risk of breast cancer among women in the Jerusalem perinatal study. Breast Cancer Res Treat 2008;108(1):129-135.

(102) Friedlander Y, Schwartz SM, Durst R, Meiner V, Robertson AS, Erez G, et al. SREBP-2 and SCAP isoforms and risk of early onset myocardial infarction. Atherosclerosis 2008;196(2):896-904.

(103) Kleinhaus K, Perrin MC, Manor O, Friedlander Y, Calderon-Margalit R, Harlap S, et al. Paternal age and twinning in the Jerusalem Perinatal Study. Eur J Obstet Gynecol Reprod Biol 2008;141(2):119-122.

(104) Weiss-Salz I, Harlap S, Friedlander Y, Kaduri L, Levy-Lahad E, Yanetz R, et al. Ethnic ancestry and increased paternal age are risk factors for breast cancer before the age of 40 years. Eur J Cancer Prev 2007;16(6):549-554.

(105) Friedlander Y, Paltiel O, Manor O, Deutsch L, Yanetz R, Calderon-Margalit R, et al. Birthweight of Offspring and Mortality of Parents: The Jerusalem Perinatal Study Cohort. Ann Epidemiol 2007;17(11):914-922.

(106) Perrin MC, Terry MB, Kleinhaus K, Deutsch L, Yanetz R, Tiram E, et al. Gestational diabetes as a risk factor for pancreatic cancer: A prospective cohort study. BMC Med 2007;5.

(107) Harlap S, Friedlander Y, Barchana M, Calderon R, Deutsch L, Kleinhaus KR, et al. Late fetal death in offspring and subsequent incidence of prostate cancer in fathers: The Jerusalem perinatal study cohort. Prostate 2007;67(9):989-998.

(108) Harlap S, Calderon-Margalit R, Perrin MC, Kleinhaus KR, Friedlander Y. Response: Re: Prostate cancer in fathers with fewer male offspring: The Jerusalem perinatal study cohort [8]. J Natl Cancer Inst 2007;99(11):903-904.

(109) Calderon-Margalit R, Friedlander Y, Yanetz R, Deutsch L, Manor O, Harlap S, et al. Late stillbirths and long-term mortality of mothers. Obstet Gynecol 2007;109(6):1301-1308.

(110) Harlap S, Davies AM, Deutsch L, Calderon-Margalit R, Manor O, Paltiel O, et al. The Jerusalem Perinatal Study cohort, 1964-2005: Methods and a review of the main results. Paediatr Perinat Epidemiol 2007;21(3):256-273.

(111) Simons LA, Simons J, Friedlander Y, McCallum J. Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? The Dubbo Study. Med J Aust 2007;186(8):400-403.

(112) Paltiel O, Friedlander Y, Deutsch L, Yanetz R, Calderon-Margalit R, Tiram E, et al. The interval between cancer diagnosis among mothers and offspring in a population-based cohort. Fam Cancer 2007;6(1):121-129.

(113) McCallum J, Simons LA, Simons J, Friedlander Y. Delaying dementia and nursing home placement: The Dubbo study of elderly Australians over a 14-year follow-up. Ann New York Acad Sci 2007;1114:121-129.

(114) Samuels-Kalow ME, Funai EF, Buhimschi C, Norwitz E, Perrin M, Calderon-Margalit R, et al. Prepregnancy body mass index, hypertensive disorders of pregnancy, and long-term maternal mortality. Am J Obstet Gynecol 2007;197(5):490.e1-490.e6.

(115) Harlap S, Paltiel O, Friedlander Y, Ronit C-, Deutsch L, Kleinhaus KR, et al. Prostate cancer in fathers with fewer male offspring: The jerusalem perinatal study cohort. J Natl Cancer Inst 2007;99(1):77-81.

(116) Danesh J, Erqou S, Walker M, Thompson SG, Tipping R, Ford C, et al. The emerging risk factors collaboration: Analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol 2007;22(12):839-869.

(117) Durst R, Jansen A, Erez G, Bravdo R, Butbul E, Ben Avi L, et al. The discrete and combined effect of SREBP-2 and SCAP isoforms in the control of plasma lipids among familial hypercholesterolaemia patients. Atherosclerosis 2006;189(2):443-450.

(118) Friedlander Y, Kark JD, Sinnreich R, Tracy RP, Siscovick DS. Fibrinogen and CRP in Israeli families: Genetic and environmental sources of concentrations and longitudinal changes. Atherosclerosis 2006;189(1):169-177.

(119) Paltiel O, Laniado DE, Yanetz R, Deutsch L, Calderon-Margalit R, Harlap S, et al. The risk of cancer following hospitalization for infection in infancy: A population-based cohort study. Cancer Epidemiol Biomarkers Prev 2006;15(10):1964-1968.

(120) Kleinhaus K, Perrin M, Friedlander Y, Paltiel O, Malaspina D, Harlap S. Paternal age and spontaneous abortion. Obstet Gynecol 2006;108(2):369-377.

(121) Bercovich D, Friedlander Y, Korem S, Houminer A, Hoffman A, Kleinberg L, et al. The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia. Atherosclerosis 2006;185(1):97-107.

(122) Simons LA, Simons J, McCallum J, Friedlander Y. Lifestyle factors and risk of dementia: Dubbo study of the elderly. Med J Aust 2006;184(2):68-70.

(123) McCallum J, Simons LA, Simons J, Friedlander Y. Patterns and predictors of nursing home placement over 14 years: Dubbo study of elderly Australians. Australas J Ageing 2005;24(3):169-173.

(124) Rokach A, Pollak A, Rosen L, Friedlander Y, Blumenfeld A, Reznik L, et al. Estrogen Receptor Gene Polymorphisms Are Associated with the Angiographic Extent of Coronary Artery Disease. J Clin Endocrinol Metab 2005;90(12):6556-6560.

(125) Friedlander Y, Vatta M, Sotoodehnia N, Sinnreich R, Li H, Manor O, et al. Possible association of the human KCNE1 (minK) gene and QT interval in healthy subjects: Evidence from association and linkage analyses in Israeli families. Ann Hum Genet 2005;69(6):645-656.

(126) Simons LA, Simons J, McCallum J, Friedlander Y. Impact of smoking, diabetes and hypertension on survival time in the elderly: The Dubbo Study. Med J Aust 2005;182(5):219-222.

(127) Funai EF, Friedlander Y, Paltiel O, Tiram E, Xue X, Deutsch L, et al. Long-term mortality after preeclampsia. Epidemiology 2005;16(2):206-215.

(128) Funai EF, Paltiel OB, Malaspina D, Friedlander Y, Deutsch L, Harlap S. Risk factors for pre-eclampsia in nulliparous and parous women: The Jerusalem Perinatal Study. Paediatr Perinat Epidemiol 2005;19(1):59-68.

(129) Kim H, Friedlander Y, Longstreth Jr. WT, Edwards KL, Schwartz SM, Siscovick DS. Family history as a risk factor for stroke in young women. Am J Prev Med 2004;27(5):391-396.

(130) Manor O, Eisenbach Z, Friedlander Y, Kark JD. Educational differentials in mortality from cardiovascular disease among men and women: The Israel Longitudinal Mortality Study. Ann Epidemiol 2004;14(7):453-460.

(131) Paltiel O, Harlap S, Deutsch L, Knaanie A, Massalha S, Tiram E, et al. Birth weight and other risk factors for acute leukemia in the Jerusalem Perinatal Study cohort. Cancer Epidemiol Biomarkers Prev 2004;13(6):1057-1064.

(132) Paltiel O, Friedlander Y, Tiram E, Barchana M, Xue X, Harlap S. Cancer after pre-eclampsia: Follow up of the Jerusalem perinatal study cohort. Br Med J 2004;328(7445):919-921.

(133) Cohen T, Vardi-Saliternik R, Friedlander Y. Consanguinity, intracommunity and intercommunity marriages in a population sample of Israeli Jews. Ann Hum Biol 2004;31(1):38-48.

(134) Neumark YD, Friedlander Y, Durst R, Leitersdorf E, Jaffe D, Ramchandani VA, et al. Alcohol Dehydrogenase Polymorphisms Influence Alcohol-Elimination Rates in a Male Jewish Population. Alcohol Clin Exp Res 2004;28(1):10-14.

(135) Friedlander Y, Paltiel O, Deutsch L, Knaanie A, Massalha S, Tiram E, et al. Birthweight and relationship with infant, child and adult mortality in the Jerusalem perinatal study. Paediatr Perinat Epidemiol 2003;17(4):398-406.

(136) Miserez AR, Muller PY, Barella L, Barella S, Staehelin HB, Leitersdorf E, et al. Erratum: Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia (Atherosclerosis (2002) 164 (15-26) PII: S0021915001007626). Atherosclerosis 2003;167(2):371.

(137) Simons LA, Simons J, Friedlander Y, McCallum J, Palaniappan L. Risk functions for prediction of cardiovascular disease in elderly Australians: The Dubbo Study. Med J Aust 2003;178(3):113-116.

(138) Katz-Leurer M, Shochina M, Carmeli E, Friedlander Y. The Influence of Early Aerobic Training on the Functional Capacity in Patients with Cerebrovascular Accident at the Subacute Stage. Arch Phys Med Rehabil 2003;84(11):1609-1614.

(139) Friedlander Y, Kark JD, Sinnreich R, Basso F, Humphries SE. Combined segregation and linkage analysis of fibrinogen variability in Israeli families: Evidence for two quantitative-trait loci, one of which is linked to a functional variant (-58G > A) in the promoter of the α-fibrinogen gene. Ann Hum Genet 2003;67(3):228-241.

(140) Palaniappan L, Simons LA, Simons J, Friedlander Y, McCallum J. Comparison of usefulness of systolic, diastolic, and mean blood pressure and pulse pressure as predictors of cardiovascular death in patients ≥60 years of age (The Dubbo Study). Am J Cardiol 2002;90(12):1398-1401.

(141) Neumark Y, Friedlander Y. Training in survey and research methods within a Master of Public Health program. Public Health Rev 2002;30(1-4):217-229.

(142) Harlap S, Paltiel O, Deutsch L, Knaanie A, Masalha S, Tiram E, et al. Paternal age and preeclampsia. Epidemiology 2002;13(6):660-667.

(143) Neumark Y, Friedlander Y, Bar-Hamburger R. Family history and other characteristics of heroin-dependent Jewish males in Israel: Results of a case-control study. Isr Med Assoc J 2002;4(10):766-771.

(144) Vardi-Saliternik R, Friedlander Y, Cohen T. Consanguinity in a population sample of Israeli Muslim Arabs, Christian Arabs and Druze. Ann Hum Biol 2002;29(4):422-431.

(145) Miserez AR, Muller PY, Barella L, Barella S, Staehelin HB, Leitersdorf E, et al. Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia. Atherosclerosis 2002;164(1):15-26.

(146) Reiner AP, Rosendaal FR, Reitsma PH, Lemaitre RN, Pearce RM, Friedlander Y, et al. Factor V Leiden, prothrombin G20210A, and risk of sudden coronary death in apparently healthy persons. Am J Cardiol 2002;90(1):66-68.

(147) Friedlander Y, Siscovick DS, Arbogast P, Psaty BM, Weinmann S, Lemaitre RN, et al. Sudden death and myocardial infarction in first degree relatives as predictors of primary cardiac arrest. Atherosclerosis 2002;162(1):211-216.

(148) Simons LA, Simons J, Friedlander Y, McCallum J. Risk factors for acute myocardial infarction in the elderly (The Dubbo Study). Am J Cardiol 2002;89(1):69-72.

(149) Simons LA, Simons J, Friedlander Y, McCallum J. Cholesterol and other lipids predict coronary heart disease and ischaemic stroke in the elderly, but only in those below 70 years. Atherosclerosis 2001;159(1):201-208.

(150) Ligumsky M, Lysy J, Siguencia G, Friedlander Y. Effect of long-term, continuous versus alternate-day omeprazole therapy on serum gastrin in patients treated for reflux esophagitis. J Clin Gastroenterol 2001;33(1):32-35.

(151) Friedlander Y, Arbogast P, Schwartz SM, Marcovina SM, Austin MA, Rosendaal FR, et al. Family history as a risk factor for early onset myocardial infarction in young women. Atherosclerosis 2001;156(1):201-207.

(152) Yehuda AB, Globerson A, Krichevsky S, Bar On H, Kidron M, Friedlander Y, et al. Ageing and the mismatch repair system. Mech Ageing Dev 2001;121(1-3):173-179.

(153) Shalev RS, Manor O, Kerem B, Ayali M, Badichi N, Friedlander Y, et al. Developmental dyscalculia is a familial learning disability. J Learn Disabil 2001;34(1):59-65.

(154) Dwolatzky T, Berezovski S, Friedmann R, Paz J, Clarfield AM, Stessman J, et al. A prospective comparison of the use of nasogastric and percutaneous endoscopic gastrostomy tubes for long-term enteral feeding in older people. Clin Nutr 2001;20(6):535-540.

(155) Durst R, Colombo R, Shpitzen S, Avi LB, Friedlander Y, Wexler R, et al. Recent origin and spread of a common lithuanian mutation, G197del LDLR, causing familial hypercholesterolemia: Positive selection is not always necessary to account for disease incidence among Ashkenazi Jews. Am J Hum Genet 2001;68(5):1172-1188.

(156) Pollak RD, Friedlander Y, Pollak A, Idelson M, Bejarano-Achache I, Blumenfeld A. Ethnic differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy Israeli populations. Genet Test 2000;4(3):309-311.

(157) Friedlander Y, Talmud PJ, Edwards KL, Humphries SE, Austin MA. Sib-pair linkage analysis of longitudinal changes in lipoprotein risk factors and lipase genes in women twins. J Lipid Res 2000;41(8):1302-1309.

(158) Friedlander Y, Leitersdorf E, Vecsler R, Funke H, Kark J. The contribution of candidate genes to the response of plasma lipids and lipoproteins to dietary challenge. Atherosclerosis 2000;152(1):239-248.

(159) Sinnreich R, Friedlander Y, Luria MH, Sapoznikov D, Kark J. Erratum: Inheritance of heart rate variability: The kibbutzim family study (Human Genetics (1999) 105 (654-661)). Hum Genet 2000;107(1):96.

(160) Simons LA, McCallum J, Friedlander Y, Ortiz M, Simons J. Moderate alcohol intake is associated with survival in the elderly: The Dubbo study. Med J Aust 2000;173(3):121-124.

(161) Simons LA, Simons J, McCallum J, Friedlander Y. Pet ownership is not associated with future health, a nine year prospective study in older Australians. Australas J Ageing 2000;19(3):139-142.

(162) Kark JD, Sinnreich R, Leitersdorf E, Friedlander Y, Shpitzen S, Luc G. Taq1B CETP polymorphism, plasma CETP, lipoproteins, apolipoproteins and sex differences in a Jewish population sample characterized by low HDL- cholesterol. Atherosclerosis 2000;151(2):509-518.

(163) Muszkat M, Ben Yehuda A, Schein MH, Friedlander Y, Naveh P, Greenbaum E, et al. Local and systemic immune response in community-dwelling elderly after intranasal or intramuscular immunization with inactivated influenza vaccine. J Med Virol 2000;61(1):100-106.

(164) Bar-On H, Kidron M, Friedlander Y, Ben-Yehuda A, Selhub J, Rosenberg IH, et al. Plasma total homocysteine levels in subjects with hyperinsulinemia. J Intern Med (GBR) 2000;247(2):287-294.

(165) Manor O, Israeli A, Friedlander Y, Eisenbach Z. Mortality differentials among women: The Israel Longitudinal Mortality Study. Soc Sci Med 2000;51(8):1175-1188.

(166) Simons LA, Friedlander Y, McCallum J, Simons J. Fasting plasma glucose in non-diabetic elderly women predicts increased all-causes mortality and coronary heart disease risk. Aust New Zealand J Med 2000;30(1):41-47.

(167) Simons LA, McCallum J, Friedlander Y, Simons J. Healthy ageing is associated with reduced and delayed disability. Age Ageing 2000;29(2):143-148.

(168) Rantala M, Rantala TT, Savolainen MJ, Friedlander Y, Kesäniemi YA. Apolipoprotein B gene polymorphisms and serum lipids: Meta-analysis of the role of genetic variation in responsiveness to diet. Am J Clin Nutr 2000;71(3):713-724.

(169) Friedlander Y, Kidron M, Caslake M, Lamb T, McConnell M, Bar-On H. Low density lipoprotein particle size and risk factors of insulin resistance syndrome. Atherosclerosis 2000;148(1):141-149.

(170) Shpichinetsky V, Raz I, Friedlander Y, Goldschmidt N, Wexler ID, Ben-Yehuda A, et al. The association between two common mutations C677T and A1298C in human methylenetetrahydrofolate reductase gene and the risk for diabetic nephropathy in type II diabetic patients. J Nutr 2000;130(10):2493-2497.

(171) Knoblauch H, Müller-Myhsok B, Busjahn A, Avi LB, Bähring S, Baron H, et al. A cholesterol-lowering gene maps to chromosome 13q. Am J Hum Genet 2000;66(1):157-166.

(172) Friedlander Y, Lapidos T, Sinnreich R, Kark JD. Genetic and environmental sources of QT interval variability in Israeli families: The kibbutz settlements family study. Clin Genet 1999;56(3):200-209.

(173) Liyou N, Davis D, James K, Simons L, Friedlander Y, Simons J, et al. The A1166C mutation in the angiotensin II type I receptor and hypertension in the elderly. Clin Exp Pharmacol Physiol 1999;26(7):525-526.

(174) Vardi R, Cohen T, Friedlander Y. Can we rely on family history? [4]. Am J Med Genet 1999;82(1):94.

(175) Cooper-Kazaz R, Friedlander Y, Steinberg A, Sonnenblick M. Longitudinal changes in attitudes of offspring concerning life- sustaining measures for their terminally ill parents. J Am Geriatr Soc 1999;47(11):1337-1341.

(176) Manor O, Eisenbach Z, Peritz E, Friedlander Y. Mortality differentials among Israeli men. Am J Public Health 1999;89(12):1807-1813.

(177) Sinnreich R, Friedlander Y, Luria MH, Sapoznikov D, Kark JD. Inheritance of heart rate variability: The kibbutzim family study. Hum Genet 1999;105(6):654-661.

(178) Friedlander Y, Kark JD, Sinnreich R, Edwards KL, Austin MA. Inheritance of LDL peak particle diameter: Results from a segregation analysis in Israeli families. Genet Epidemiol 1999;16(4):382-396.

(179) Friedman G, Goldschmidt N, Friedlander Y, Ben-Yehuda A, Selhub J, Babaey S, et al. A common mutation A1298C in human methylenetetrahydrofolate reductase gene: Association with plasma total homocysteine and folate concentrations. J Nutr 1999;129(9):1656-1661.

(180) Sinnreich R, Friedlander Y, Sapoznikov D, Kark JD. Familial aggregation of heart rate variability based on short recordings - The kibbutzim family study. Hum Genet 1998;103(1):34-40.

(181) Neumark YD, Friedlander Y. Familial resemblance of alcohol consumption levels in Jewish families. Alcohol Alcohol 1998;33(5):509-518.

(182) Shilo S, Berezovsky S, Friedlander Y, Sonnenblick M. Hypoglycemia in hospitalized nondiabetic older patients. J Am Geriatr Soc 1998;46(8):978-982.

(183) Simons LA, McCallum J, Friedlander Y, Simons J. Risk factors for ischemic stroke: Dubbo study of the elderly. Stroke 1998;29(7):1341-1346.

(184) Neumark YD, Friedlander Y, Thomasson HR, Li T-. Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: A pilot study. J Stud Alcohol 1998;59(2):133-139.

(185) Sinnreich R, Kark JD, Friedlander Y, Sapoznikov D, Luria MH. Five minute recordings of heart rate variability for population studies: Repeatability and age-sex characteristics. Heart 1998;80(2):156-162.

(186) Liyou N, Simons L, Friedlander Y, Simons J, McCallum J, O'Shaughnessy K, et al. Coronary artery disease is not associated with the E298→D variant of the constitutive, endothelial nitric oxide synthase gene [2]. Clin Genet 1998;54(6):528-529.

(187) Friedlander Y, Siscovick DS, Weinmann S, Austin MA, Psaty BM, Lemaitre RN, et al. Family history as a risk factor for primary cardiac arrest. Circulation 1998;97(2):155-160.

(188) Friedman G, Ben-Yehuda A, Dabach Y, Ben-Naim M, Hollander G, Retter O, et al. Scavenger receptor activity and expression of apolipoprotein E mRNA in monocyte-derived macrophages of young and old healthy men. Atherosclerosis 1997;128(1):67-73.

(189) Simons LA, McCallum J, Simons J, Friedlander Y. Relationship of peak expiratory flow rate with mortality and ischaemic heart disease in elderly Australians. Med J Aust 1997;166(10):526-529.

(190) Friedlander Y, Austin MA, Newman B, Edwards K, Mayer-Davis EJ, King M-. Heritability of longitudinal changes in coronary-heart-disease risk factors in Women Twins. Am J Hum Genet 1997;60(6):1502-1512.

(191) Dann EJ, Friedlander Y, Leitersdorf E, Nagler A. The modulation of plasma lipids and lipoproteins during bone marrow transplantation is unrelated to exogenously administered recombinant human granulocyte-monocyte colony-stimulating factor (rHu GM-CSF). Med Oncol 1996;13(2):81-86.

(192) Friedlander Y, Leitersdorf E. Influence of apolipoprotein E genotypes on plasma lipid and lipoprotein concentrations: Results from a segregation analysis in pedigrees with molecularly defined familial hypercholesterolemia. Genet Epidemiol 1996;13(2):159-177.

(193) Kark JD, Carmel S, Sinnreich R, Goldberger N, Friedlander Y. Psychosocial factors among members of religious and secular kibbutzim. Isr J Med Sci 1996;32(3-4):185-194.

(194) Johnson AG, Simons LA, Friedlander Y, Simons J, Davis DR, MaCallum J. I/D polymorphism of the angiotensin-converting enzyme gene does not predict isolated systolic or systolic-diastolic hypertension in the elderly. J Hum Hypertens 1996;10(3):167-169.

(195) Friedlander Y. Genetic contributions to LDL-C, Apo-B and LDL-C/Apo-B ratio in a sample of Israeli offspring with a parental history of myocardial infarction. Clin Genet 1996;50(1):1-9.

(196) Simons LA, McCallum J, Friedlander Y, Simons J. Predictors of mortality in the prospective Dubbo study of Australian elderly. AUST NEW ZEALAND J MED 1996;26(1):40-48.

(197) Simons LA, McCallum J, Friedlander Y, Simons J. Alcohol intake and survival in the elderly: A 77 month follow-up in the Dubbo study. AUST NEW ZEALAND J MED 1996;26(5):662-670.

(198) Simons LA, McCallum J, Friedlander Y, Simons J. Diabetes, mortality and coronary heart disease in the prospective Dubbo study of Australian elderly. AUST NEW ZEALAND J MED 1996;26(1):66-74.

(199) Simons L, Simons J, Friedlander Y, McCallum J, Sjogren B. Chronic bronchitis and risk of coronary heart disease [14]. Lancet 1996;348(9038):1388-1389.

(200) Kark JD, Shemi G, Friedlander Y, Martin O, Manor O, Blondheim SH. Does religious observance promote health? Mortality in secular vs religious Kibbutzim in Israel. Am J Public Health 1996;86(3):341-346.

(201) Johnson AG, Simons LA, Friedlander Y, Simons J, Davis DR, MaCallum J. M235 → T polymorphism of the angiotensinogen gene predicts hypertension in the elderly. J Hypertens 1996;14(9):1061-1065.

(202) Eliav O, Schurr D, Pfister P, Friedlander Y, Leitersdorf E. High-dose fluvastatin and bezafibratecombination treatment for heterozygous familial hypercholesterolemia. Am J Cardiol 1995;76(1-2 SUPPL. 1):76A-79A.

(203) Friedlander Y. Sibling correlations of coronary heart disease risk factors in a sample of Israeli offspring with parental history of myocardial infarction. Atherosclerosis 1995;113(2):259-271.

(204) Friedlander Y, Leitersdorf E. Segregation analysis of plasma lipoprotein(a) levels in pedigrees with molecularly defined familial hypercholesterolemia. Genet Epidemiol 1995;12(2):129-143.

(205) Friedlander Y, Kark JD, Kidron M, Bar-On H. Univariate and bivariate admixture analyses of serum glucose and glycated hemoglobin distributions in a Jerusalem population sample. Hum Biol 1995;67(1):151-170.

(206) Simons LA, Friedlander Y, McCallum J, Simons J. Risk factors for coronary heart disease in the prospective Dubbo Study of Australian elderly. Atherosclerosis 1995;117(1):107-118.

(207) Friedlander Y, Elkana Y, Sinnreich R, Kark JD. Genetic and environmental sources of fibrinogen variability in Israeli families: The Kibbutzim family study. Am J Hum Genet 1995;56(5):1194-1206.

(208) Friedlander Y, Berry EM, Eisenberg S, Stein Y, Leitersdorf E. Plasma lipids and lipoproteins response to a dietary challenge: analysis of four candidate genes. Clin Genet 1995;47(1):1-12.

(209) Leitersdorf E, Safadi R, Meiner V, Reshef A, Björkhem I, Friedlander Y, et al. Cerebrotendinous xanthomatosis in the Israeli druze: Molecular genetics and phenotypic characteristics. Am J Hum Genet 1994;55(5):907-915.

(210) Sonnenblick M, Nesher G, Friedlander Y, Rubinow A. Giant cell arteritis in Jerusalem: A 12-year epidemiological study. Rheumatology (UK) 1994;33(10):938-941.

(211) Nesher G, Sonnenblick M, Friedlander Y. Analysis of steroid related complications and mortality in temporal arteritis: A 15-year survey of 43 patients. J Rheumatol 1994;21(7):1283-1286.

(212) McCallum J, Simons J, Simons L, Friedlander Y. Low serum cholesterol is not associated with depression in the elderly: data from an Australian community study. Aust New Zealand J Med 1994;24(5):561-564.

(213) Simons L, Simons J, Mccallum J, Friedlander Y. Serum lipids and depression. Lancet 1993;341(8851):1028.

(214) Friedlander Y, Dann EJ, Leitersdorf E. Absence of familial defective apolipoprotein B-100 in Israeli patients with dominantly inherited hypercholesterolemia and in offspring with parental history of myocardial infarction. Hum Genet 1993;91(3):299-300.

(215) Kark JD, Sandholzer C, Friedlander Y, Utermann G. Plasma Lp(a), apolipoprotein(a) isoforms and acute myocardial infarction in men and women: a case-control study in the Jerusalem population. Atherosclerosis 1993;98(2):139-151.

(216) Sonnenblick M, Friedlander Y, Rosin AJ. Diuretic-induced severe hyponatremia review and analysis of 129 reported patients. Chest 1993;103(2):601-606.

(217) Sonnenblick M, Friedlander Y, Steinberg A. Dissociation between the Wishes of Terminally Ill Parents and Decisions by Their Offspring. J Am Geriatr Soc 1993;41(6):599-604.

(218) Friedlander Y, Merom DL, Kark JD. A comparison of different matching designs in case‐control studies: An empirical example using continuous exposures, continuous confounders and incidence of myocardial infarction. Stat Med 1993;12(11):993-1004.

(219) Simons L, Friedlander Y, Simons J, McCallum J. Lipoprotein(a) is not associated with coronary heart disease in the elderly: cross-sectional data from the Dubbo study. Atherosclerosis 1993;99(1):87-95.

(220) Friedlander Y, Kaufmann NA, Cedar H, Kark JD. XbaI polymorphism of the apolipoprotein B gene and plasma lipid and lipoprotein response to dietary fat and cholesterol: a clinical trial. Clin Genet 1993;43(5):223-231.

(221) Johnson A, Simons L, Simons J, Friedlander Y, McCallum J. Non‐steroidal anti‐inflammatory drugs and hypertension in the elderly: a community‐based cross‐sectional study. Br J Clin Pharmacol 1993;35(5):455-459.

(222) Leitersdorf E, Eisenberg S, Eliav O, Friedlander Y, Berkman N, Dann EJ, et al. Genetic determinants of responsiveness to the HMG-CoA reductase inhibitor fluvastatin in patients with molecularly defined heterozygous familial hypercholesterolemia. Circulation 1993;87(4 SUPPL.):III35-III44.

(223) Simons LA, McCallum J, Simons J, Friedlander Y. Health status and lifestyle in elderly Hawaii Japanese and Australian men. Med J Aust 1992;157(3):188-190.

(224) Simons LA, Simons J, McCallum K, Friedlander Y. Dubbo Study of the elderly: hypertension and lipid levels. Atherosclerosis 1992;92(1):59-65.

(225) Simons LA, Tett S, Simons J, Lauchlan R, McCallum J, Friedlander Y, et al. Multiple medication use in the elderly: Use of prescription and non-prescription drugs in an Australian community setting. Med J Aust 1992;157(4):242+244-246.

(226) Berry EM, Eisenberg S, Friedlander Y, Harats D, Kaufmann NA, Norman Y, et al. Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins-the Jerusalem nutrition study. II. Monounsaturated fatty acids vs carbohydrates. Am J Clin Nutr 1992;56(2):394-403.

(227) Oppenheim A, Friedlander Y, Dann EJ, Berkman N, Schwarte SP, Leitersdorf E. Hypercholesterolemia in five Israeli Christian-Arab kindreds is caused by the "Lebanese" allele at the low density lipoprotein receptor gene locus and by an additional independent major factor. Hum Genet 1991;88(1):75-84.

(228) Brownstein Z, Friedlander Y, Peritz E, Cohen T. Estimated number of loci for autosomal recessive severe nerve deafness within the Israeli Jewish population, with implications for genetic counseling. Am J Med Genet 1991;41(3):306-312.

(229) Simons LA, Simons J, McCallum J, Powell I, Friedlander Y, Heller R. Dubbo study of the elderly: sociological and cardiovascular risk factors at entry. Aust New Zealand J Med 1991;21(5):701-709.

(230) Leitersdorf E, Friedlander Y, Bard J-, Fruchart J-, Eisenberg S, Stein Y. Diverse effect of ethnicity on plasma lipoprotein[a] levels in heterozygote patients with familial hypercholesterolemia. J Lipid Res 1991;32(9):1513-1519.

(231) Simons LA, Balasubramaniam S, Szanto A, Simons J, Friedlander Y, Hickie JB, et al. High density lipoproteins, genetic polymorphism for apo A‐I and coronary artery disease. Aust New Zealand J Med 1991;21(3):330-334.

(232) Berry EM, Eisenberg S, Haratz D, Friedlander Y, Norman Y, Kaufmann NA, et al. Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins - the Jerusalem nutrition study: High MUFAs vs high PUFAs. Am J Clin Nutr 1991;53(4):899-907.

(233) Simons LA, Friedlander Y, McCallum J, Simons J, Powell I, Heller R, et al. The Dubbo Study of the Health of Elderly: Correlates of Coronary Heart Disease at Study Entry. J Am Geriatr Soc 1991;39(6):584-590.

(234) Sonnenblick M, Carmon M, Rudenski B, Friedlander Y, Van Dijk JM. Septicemia in the elderly: Incidence, etiology and prognostic factors. Isr J Med Sci 1990;26(4):195-199.

(235) Friedlander Y, Adler B, Palti H. Trends in sibling correlations for height and weight: The effect of age changes (0-24 months) and spacing between siblings (0-10 years). Hum Biol 1989;61(2):271-285.

(236) Levav I, Friedlander Y, Kark JD, Peritz E. An Epidemiologic Study of Mortality among Bereaved Parents. New Engl J Med 1988;319(8):457-461.

(237) Friedlander Y, Kark JD, Stein Y. Family resemblance for serum uric acid in a Jerusalem sample of families. Hum Genet 1988;79(1):58-63.

(238) Friedlander Y, Kark JD, Stein Y. Biological and environmental sources of familial aggregation of blood pressure: The jerusalem lipid research clinic. Int J Epidemiol 1988;17(1):70-76.

(239) Sonnenblick M, Slotki IN, Friedlander Y, Kramer MR. Acute Renal Failure in the Elderly Treated by One‐Time Peritoneal Dialysis. J Am Geriatr Soc 1988;36(11):1039-1044.

(240) Simons LA, Friedlander Y, Simons J, Kark JD. Familial aggregation of coronary heart disease: partial mediation by high density lipoproteins? Atherosclerosis 1988;69(2-3):139-144.

(241) Friedlander Y, Kark JD, Kaufmann NA, Berry EM, Stein Y. Familial aggregation of body mass index in ethnically diverse families in Jerusalem. The Jerusalem Lipid Research Clinic. Int J Obes 1988;12(3):237-247.

(242) Bucher KD, Friedlander Y, Kaplan EB, Namboodiri KK, Kark JD, Eisenberg S, et al. Biological and cultural sources of familial resemblance in plasma lipids: A comparison between North America and Israel—the lipid research clinics program. Genet Epidemiol 1988;5(1):17-33.

(243) Gofin R, Kark JD, Friedlander Y, Lewis BS, Witt H, Stein Y, et al. Peripheral vascular disease in a middle-aged population sample. The Jerusalem Lipid Research Clinic Prevalence Study. Isr J Med Sci 1987;23(3):157-167.

(244) Friedlander Y, Kark JD. Letter to the editor. Int J Cardiol 1987;16(3):322-323.

(245) Friedlander Y, Kark JD. Complex segregation analysis of plasma lipid and lipoprotein variables in a Jerusalem sample of nuclear families. Hum Hered 1987;37(1):7-19.

(246) Friedlander Y, Kark JD, Bar‐On H. Family resemblance for fasting blood glucose: the Jerusalem Lipid Research Clinic. Clin Genet 1987;32(4):222-234.

(247) Friedlander Y, Kark JD, Stein Y. Religious observance and plasma lipids and lipoproteins among 17-year-old Jewish residents of Jerusalem. Prev Med 1987;16(1):70-79.

(248) Friedlander Y, Bucher KD, Namboodiri KK, Heiss G, Kark JD, Tyroler HA, et al. Parent-offspring aggregation of plasma lipids in selected populations in North America and Israel: The lipid research clinics prevalence study. Am J Epidemiol 1987;126(2):268-279.

(249) Zimmerman J, Eisenberg S, Kaufmann NA, Fainaru M, Oschry Y, Friedlander Y, et al. Effect of moderate isocaloric modification of dietary carbohydrate on high-density lipoprotein composition and apolipoprotein A-1 turnover in humans. Isr J Med Sci 1986;22(2):95-104.

(250) Friedlander Y. Letters to the editor. Int J Cardiol 1986;12(2):270-271.

(251) Friedlander Y, Kark JD, Stein Y. Complex segregation analysis of low levels of plasma high-density lipoprotein cholesterol in a sample of nuclear families in Jerusalem. Genet Epidemiol 1986;3(5):285-297.

(252) Friedlander Y, Kark JD, Stein Y. Heterogeneity in multifactorial inheritance of plasma lipids and lipoproteins in ethnically diverse families in Jerusalem. Genet Epidemiol 1986;3(2):95-112.

(253) Friedlander Y, Kark JD, Stein Y. Religious orthodoxy and myocardial infarction in Jerusalem - a case control study. Int J Cardiol 1986;10(1):33-41.

(254) Kark JD, Friedlander Y, Stein Y. Blood group and height in a multiethnic population. Hum Hered 1986;36(3):188-191.

(255) Friedlander Y, Kark JD, Stein Y. Biological and environmental sources of variation in plasma lipids and lipoproteins: The Jerusalem lipid research clinic1. Hum Hered 1986;36(3):143-153.

(256) Kaufmann NA, Dennis BH, Heiss G, Friedlander Y, Kark JD, Stein Y. Comparison of nutrient intakes of selected populations in the United States and Israel: The lipid research clinics prevalence study. Am J Clin Nutr 1986;43(4):604-620.

(257) Leitersdorf E, Gottehrer N, Fainaru M, Friedlander Y, Friedman G, Tzivom D, et al. Analysis of risk factors in 532 survivors of first myocardial infarction hospitalized in Jerusalem. Atherosclerosis 1986;59(1):75-93.

(258) Eisenberg S, Heiss G, Friedlander Y, Rifkind B, Segal P, Williams OD, et al. Comparison of plasma lipids, lipoproteins and dyslipoproteinemia in Israel and the United States. The lipid research clinics program prevalence study. Atherosclerosis 1986;59(1):63-74.

(259) Gofin R, Lewis BS, Kark JD, Witt H, Friedlander Y, Kimchi A, et al. Treadmill exercise testing in a middle-aged Jerusalem population sample. The Jerusalem lipid research clinic prevalence study. Isr J Med Sci 1985;21(7):584-594.

(260) Kark JD, Friedlander Y, Kaufmann NA, Stein Y. Coffee, tea, and plasma cholesterol: The Jerusalem Lipid Research Clinic prevalence study. Brit Med J 1985;291(6497):699-704.

(261) Friedlander Y, Kark JD, Stein Y. Variability of plasma lipids and lipoproteins: the Jerusalem Lipid Research Clinic Study. Clin Chem 1985;31(7):1121-1126.

(262) Friedlander Y, Kark JD, Stein Y. Family history of myocardial infarction as an independent risk factor for coronary heart disease. Br Heart J 1985;53(4):382-387.

(263) Slater PE, Kaufmann NA, Friedlander Y, Stein Y. Effects of smoking and physical activity on serum uric acid in a jerusalem population sample. Ann Hum Biol 1985;12(2):179-184.

(264) Friedlander Y, Kark JD, Kaufmann NA, Stein Y. Coronary heart disease risk factors among religious groupings in a Jewish population sample in Jerusalem. Am J Clin Nutr 1985;42(3):511-521.

(265) Friedlander Y, Kark JD, Fainaru M, Gotsman M, Stein Y. Aggregation of plasma lipids and lipoproteins in families with and without coronary heart disease. Atherosclerosis 1985;57(2-3):235-247.

(266) Kark JD, Friedlander Y. ABO and Rh blood groups and blood pressures in Jerusalem 17 year olds. Hum Biol 1984;56(4):759-769.

(267) Slater PE, Kark JD, Friedlander Y, Kaufmann NA. Determinants of thyroid hormone and thyroid-lipid interrelationships in Jerusalem. Isr J Med Sci 1984;20(12):1158-1163.

(268) Levene C, Steinberg AG, Friedlander Y, Brautbar C, Cohen T. Genetic polymorphisms among Bukharan and Georgian Jews in Israel. Am J Med Genet 1984;19(4):623-641.

(269) Friedlander Y, Kark JD. Familial aggregation of blood pressure in a Jewish population sample in Jerusalem among ethnic and religious groupings. Soc Biol 1984;31(1-2):75-90.

(270) Levene C, Medalie JH, Friedlander Y, Cohen T. The distribution of ABO, MNSs, Rhesus, Kell, Duffy and Kidd blood groups of jews originating from 20 countries. Isr J Med Sci 1984;20(6):509-518.

(271) Kark JD, Troya G, Friedlander Y, Slater PE, Stein Y. Validity of maternal reporting of breast feeding history and the association with blood lipids in 17 year olds in Jerusalem. J Epidemiol Community Health 1984;38(3):218-225.

(272) Friedlander Y, Kark JD, Cohen T, Kaufmann NA, Eisenberg S, Stein Y. Admixture analysis of plasma cholesterol levels in a jewish population sample in Jerusalem. Hum Hered 1984;34(2):82-95.

(273) Zimmerman J, Kaufmann NA, Fainaru M, Eisenberg S, Oschry Y, Friedlander Y, et al. Effect of weight loss in moderate obesity on plasma lipoprotein and apolipoprotein levels and on high density lipoprotein composition. Arteriosclerosis 1984;4(2):115-123.

(274) Flugelman MY, Hasin Y, Tur‐Caspa I, Friedlander Y, Gotsman MS. Prediction of in‐hospital ventricular fibrillation from admission data in acute myocardial infarction. Clin Cardiol 1983;6(4):156-162.

(275) Friedlander Y, Kark JD, Cohen T, Eisenberg S, Stein Y. Admixture analysis of high density lipoprotein cholesterol distribution in a Jerusalem population sample. Clin Genet 1983;24(2):117-127.

(276) Gofin R, Kark JD, Friedlander Y. Cigarette smoking, blood pressure and pulse rate in the Jerusalem Lipid Research Clinic Prevalence Study. Isr J Med Sci 1982;18(12):1217-1222.

(277) Friedlander Y, Kark JD, Eisenberg S, Stein Y. Calculation of LDL-cholesterol from total cholesterol, triglyceride and HDL-cholesterol: A comparison of methods in the Jerusalem Lipid Research Clinic Prevalence Study. Isr J Med Sci 1982;18(12):1242-1252.

(278) Gofin J, Kark JD, Halfon ST, Friedlander Y, Stein Y. Cigarette smoking and its relation to anthropometric characteristics and biochemical variables in Jerusalem 17-year-olds and adults. Isr J Med Sci 1982;18(12):1233-1241.

(279) Halfon ST, Kark JD, Baras M, Friedlander Y, Eisenberg S. Smoking, lipids and lipoproteins in Jerusalem 17-year-olds. Isr J Med Sci 1982;18(11):1150-1157.

(280) Friedlander Y, Cohen T, Stenhouse N, Davies AM, Stein Y. Familial aggregation of total cholesterol, triglyceride and high-density lipoprotein-cholesterol in an Israeli population sample. Isr J Med Sci 1982;18(11):1137-1143.

(281) Slater PE, Kark JD, Friedlander Y, Kaufmann NA, Fainaru M, Eisenberg S. Correlates of biochemical variables in the Jerusalem Lipid Research Clinic population. Isr J Med Sci 1982;18(12):1223-1232.

(282) Kaufmann NA, Kark JD, Friedlander Y, Dennis BH, McClish D, Stein Y. Nutrient intake in Jerusalem. Effects of origin, social class and education. Isr J Med Sci 1982;18(12):1198-1209.

(283) Slater PE, Kark JD, Friedlander Y, Kaufmann NA, Eisenberg S, Stein Y. Reported physical activity and blood lipids in Jerusalem adults. Isr J Med Sci 1982;18(11):1144-1149.

(284) Harlap S, Baras M, Friedlander Y, Kaufmann NA, Eisenberg S, Davies AM, et al. Contributions of different lipoprotein fractions to variations in total cholesterol between Israeli origin groups and social classes. Isr J Med Sci 1982;18(11):1131-1136.

(285) Kaufmann NA, Friedlander Y, Halfon ST, Slater PE, Dennis BH, McClish D, et al. Nutrient intake in Jerusalem - consumption in 17-year-olds. Isr J Med Sci 1982;18(12):1167-1182.

(286) Kaufmann NA, Friedlander Y, Halfon ST, Slater PE, Dennis BH, McClish D, et al. Nutrient intake in Jerusalem. Consumption in adults. Isr J Med Sci 1982;18(12):1183-1197.

(287) Slater PE, Friedlander Y, Baras M, Harlap S, Halfon ST, Kaufmann NA, et al. The Jerusalem Lipid Research Clinic: Sampling, response and selected methodological issues. Isr J Med Sci 1982;18(11):1106-1112.

(288) Karlin S, Carmelli D, Friedlander Y, Williams PT, Cohen T, Stein Y. Association arrays for comparing familial total cholesterol, high density lipoprotein cholesterol, and triglyceride similarity in the israeli population by country of origin. Am J Epidemiol 1982;116(6):1022-1032.

(289) Eisenberg S, Ehrenfeld M, Friedman G, Friedlander Y. Risk factors for coronary artery disease in patients with acute myocardial infarction. Effects of age, sex and ethnicity. Isr J Med Sci 1981;17(5):309-317.

(290) Cohen T, Levene C, Yodfat Y, Fidel J, Friedlander Y, Steinberg AG, et al. Genetic studies on Cochin Jews in Israel: 1. Population data, blood groups, isoenzymes, and HLA determinants. Am J Med Genet 1980;6(1):61-73.

(291) Halfon ST, Friedlander Y, Halperin G, Harlap S, Dennis BH, Moore MH, et al. Plasma high-density lipoprotein cholesterol, total cholesterol and triglyceride levels in 17-year-old Jewish residents of Jerusalem: a preliminary report. The Lipid Research Clinics Program Prevalence Study. Circulation 1980;62(4 Pt 2):IV93-98.