Last updated September 2023 - School of Public Health
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Bar-Tana J. mTORC1 syndrome (TorS): unified paradigm for diabetes/metabolic syndrome. Trends in Endocrinology and Metabolism [Internet]. 2023;34(3):135–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147822908&doi=10.1016%252fj.tem.2023.01.001&partnerID=40&md5=346f9e9f7d16624af73f6008840963ce
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Bar-Tana J. TorS - Reframing a rational for type 2 diabetes treatment. Diabetes/Metabolism Research and Reviews [Internet]. 2023; Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85168684647&doi=10.1002%252fdmrr.3712&partnerID=40&md5=27e479a43d2ccec7a8423bbcbbb7fab5
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Aisen Y, Gatt ME, Hertz R, Smeir E, Bar-Tana J. Suppression of multiple myeloma by mitochondrial targeting. Scientific Reports [Internet]. 2021;11(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102521904&doi=10.1038%252fs41598-021-83829-2&partnerID=40&md5=b99bb2778776cbd0ad9ed0603c7c8c96
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Bar-Tana J. Insulin Resistance, Secretion and Clearance –Taming the Three Effector Encounter of Type 2 Diabetes. Frontiers in Endocrinology [Internet]. 2021;12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117086295&doi=10.3389%252ffendo.2021.741114&partnerID=40&md5=dce1bd693f915e377d7e499198e08c10
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Bar-Tana J. Type 2 diabetes – unmet need, unresolved pathogenesis, mTORC1-centric paradigm. Reviews in Endocrine and Metabolic Disorders [Internet]. 2020;21(4):613–29. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081538215&doi=10.1007%252fs11154-020-09545-w&partnerID=40&md5=0d98877b1c14f8d6d8928af16203af56
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Valitsky M, Hoffman A, Unterman T, Bar-Tana J. Insulin sensitizer prevents and ameliorates experimental type 1 diabetes. American Journal of Physiology - Endocrinology and Metabolism [Internet]. 2017;313(6):E672–80. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037034745&doi=10.1152%252fajpendo.00329.2016&partnerID=40&md5=5747c0976a3a3f6bb63b78dcf4deb576
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Atiq R, Hertz R, Eldad S, Smeir E, Bar-Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget [Internet]. 2016;7(14):18694–704. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84975526917&doi=10.18632%252foncotarget.7909&partnerID=40&md5=7edbf276dcbd7859021d55e0b413f699
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Gluschnaider U, Hertz R, Ohayon S, Smeir E, Smets M, Pikarsky E, et al. Long-chain fatty acid analogues suppress breast tumorigenesis and progression. Cancer Research [Internet]. 2014;74(23):6991–7002. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84917710704&doi=10.1158%252f0008-5472.CAN-14-0385&partnerID=40&md5=599544326dd7f92fd248242c119384ae
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Vainer GW, Saada A, Kania-Almog J, Amartely A, Bar-Tana J, Hertz R. PF-4708671 activates AMPK independently of p70S6K1 inhibition. PLoS ONE [Internet]. 2014;9(9). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929941964&doi=10.1371%252fjournal.pone.0107364&partnerID=40&md5=4f9f193786149cdd08213e2536015b3b
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Yehuda-Shnaidman E, Kalderon B, Bar-Tana J. Thyroid hormone, thyromimetics, and metabolic efficiency. Endocrine Reviews [Internet]. 2014;35(1):35–58. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84893579754&doi=10.1210%252fer.2013-1006&partnerID=40&md5=1fcae3f1fe2f86f6328a756d2222dca1
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Algamas-Dimantov A, Yehuda-Shnaidman E, Hertz R, Peri I, Bar-Tana J, Schwartz B. Prevention of diabetes-promoted colorectal cancer by (n-3) polyunsaturated fatty acids and (n-3) PUFA mimetic. Oncotarget [Internet]. 2014;5(20):9851–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930430618&doi=10.18632%252foncotarget.2453&partnerID=40&md5=3b6ba0fa67b4a80471e92e11fcad75f4
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Algamas-Dimantov A, Davidovsky D, Ben-Ari J, Kang JX, Peri I, Hertz R, et al. Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice. Journal of Lipid Research [Internet]. 2012;53(6):1056–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861452215&doi=10.1194%252fjlr.M021949&partnerID=40&md5=653b4d3970fd743e2c8c79b416d84d22
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Kalderon B, Azazmeh N, Azulay N, Vissler N, Valitsky M, Bar-Tana J. Suppression of adipose lipolysis by long-chain fatty acid analogs. Journal of Lipid Research [Internet]. 2012;53(5):868–78. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860281134&doi=10.1194%252fjlr.M022673&partnerID=40&md5=b2ee32e41303c4d9f4aea27e3a027c04
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Zatara G, Hertz R, Shaked M, Mayorek N, Morad E, Grad E, et al. Suppression of FoxO1 activity by long-chain fatty acyl analogs. Diabetes [Internet]. 2011;60(7):1872–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80052098833&doi=10.2337%252fdb11-0248&partnerID=40&md5=cda0c4093ccc23dfb645955f0f572c01
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Samovski D, Kalderon B, Yehuda-Shnaidman E, Bar-Tana J. Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo. Journal of Biological Chemistry [Internet]. 2010;285(10):6879–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77951245187&doi=10.1074%252fjbc.M109.080416&partnerID=40&md5=195a88c74be2701e68af2ef93632b937
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Yehuda-Shnaidman E, Kalderon B, Azazmeh N, Bar-Tana J. Gating of the mitochondrial permeability transition pore by thyroid hormone. FASEB Journal [Internet]. 2010;24(1):93–104. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-75149122418&doi=10.1096%252ffj.09-133538&partnerID=40&md5=330609a48b39ca129ae2a15f96dc4662
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Schwartz B, Algamas-Dimantav A, Hertz R, Natal J, Kerman A, Peri I, et al. Inhibition of colorectal cancer by targeting hepatocyte nuclear factor-4α. International Journal of Cancer [Internet]. 2009;124(5):1081–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-58749099293&doi=10.1002%252fijc.24041&partnerID=40&md5=3e1b9b16a87066ff919ac02c34e7cd13
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Za’tara G, Bar-Tana J, Kalderon B, Suter M, Morad E, Samovski D, et al. AMPK activation by long chain fatty acyl analogs. Biochemical Pharmacology [Internet]. 2008;76(10):1263–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-54249111313&doi=10.1016%252fj.bcp.2008.08.028&partnerID=40&md5=b0559b5918d161c2f87546d99baad498
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Shabalina IG, Backlund EC, Bar-Tana J, Cannon B, Nedergaard J. Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism. Biochimica et Biophysica Acta - Bioenergetics [Internet]. 2008;1777(7–8):642–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-50949102396&doi=10.1016%252fj.bbabio.2008.04.038&partnerID=40&md5=9bd1bdf2e117b82ecf8da093da458ce7
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Las G, Mayorek N, Dickstein K, Bar-Tana J. Modulation of insulin secretion by fatty acyl analogs. Diabetes [Internet]. 2006;55(12):3478–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845542196&doi=10.2337%252fdb06-0687&partnerID=40&md5=ed3552a68af226275b56ff6d5b431b9c
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Sheena V, Hertz R, Berman I, Nousbeck J, Bar-Tana J. Transcriptional suppression of human microsomal triglyceride transfer protein by hypolipidemic insulin sensitizers. Biochemical Pharmacology [Internet]. 2005;70(11):1548–59. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-27544465167&doi=10.1016%252fj.bcp.2005.09.004&partnerID=40&md5=0738b6788f8561ca9c3078c9fc1248aa
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Hertz R, Kalderon B, Byk T, Berman I, Za’Tara G, Mayer R, et al. Thioesterase activity and acyl-CoA/fatty acid cross-talk of hepatocyte nuclear factor-4α. Journal of Biological Chemistry [Internet]. 2005;280(26):24451–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-21644454402&doi=10.1074%252fjbc.M500732200&partnerID=40&md5=38fb6f5ae98fe586cdba3c99d5124169
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Schroeder F, Huang H, Hostetler HA, Petrescu AD, Hertz R, Bar-Tana J, et al. Stability of fatty acyl-coenzyme A thioester ligands of hepatocyte nuclear factor-4α and peroxisome proliferator-activated receptor-α. Lipids [Internet]. 2005;40(6):559–68. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-22844452801&doi=10.1007%252fs11745-005-1416-y&partnerID=40&md5=559e72ea3d576c5a540a3fe0c9aaf15f
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Magenheim J, Hertz R, Berman I, Nousbeck J, Bar-Tana J. Negative autoregulation of HNF-4α gene expression by HNF-4α1. Biochemical Journal [Internet]. 2005;388(1):325–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-19544363541&doi=10.1042%252fBJ20041802&partnerID=40&md5=47ed0b26a0e0deff33bcf2decb6105b9
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Yehuda-Shnaidman E, Kalderon B, Bar-Tana J. Modulation of mitochondrial transition pore components by thyroid hormone. Endocrinology [Internet]. 2005;146(5):2462–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-17744371879&doi=10.1210%252fen.2004-1161&partnerID=40&md5=37b46835dfe162a440b90a6c476bba40
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Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB. Role of regulatory F-domain in hepatocyte nuclear factor-4α ligand specificity. Journal of Biological Chemistry [Internet]. 2005;280(17):16714–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-20444475700&doi=10.1074%252fjbc.M405906200&partnerID=40&md5=091dadf465bf52e4d3e59052e1f0af9b
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Sheena V, Hertz R, Nousbeck J, Berman I, Magenheim J, Bar-Tana J. Transcriptional regulation of human microsomal triglyceride transfer protein by hepatocyte nuclear factor-4α. Journal of Lipid Research [Internet]. 2005;46(2):328–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-13944249827&doi=10.1194%252fjlr.M400371-JLR200&partnerID=40&md5=bb63cd3b6934a97ddbdaca4a91e2683b
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Bronner M, Hertz R, Bar-Tana J. Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor α by AMP-activated protein kinase. Biochemical Journal [Internet]. 2004;384(2):295–305. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-10644297079&doi=10.1042%252fBJ20040955&partnerID=40&md5=9878b940f762a37d95377589b02c09f1
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Bar-Tana J. Hypolipidemia induced by PPARα agonists: HNF-4α as an alternative to PPARα. Current Opinion in Investigational Drugs [Internet]. 2004;5(9):941–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-16644363226&partnerID=40&md5=5ad56e131e33c6e0cef0ef5093780b9d
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Petrescu AD, Payne HR, Boedecker A, Chao H, Hertz R, Bar-Tana J, et al. Physical and Functional Interaction of Acyl-CoA-binding Protein with Hepatocyte Nuclear Factor-4α. Journal of Biological Chemistry [Internet]. 2003;278(51):51813–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0347695020&doi=10.1074%252fjbc.M303858200&partnerID=40&md5=cb1ad8c6d261c7e5bdd287c52107883c
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Hertz R, Ben-Haim N, Petrescu AD, Kalderon B, Berman I, Eldad N, et al. Rescue of MODY-1 by agonist ligands of hepatocyte nuclear factor-4α. Journal of Biological Chemistry [Internet]. 2003;278(25):22578–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0038265502&doi=10.1074%252fjbc.M212138200&partnerID=40&md5=64e42c16b08a24cb29fe348978f03680
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Kalderon B, Mayorek N, Ben-Yaacov L, Bar-Tana J. Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo. American Journal of Physiology - Endocrinology and Metabolism [Internet]. 2003;284(4 47-4):E795–803. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037376373&doi=10.1152%252fajpendo.00368.2002&partnerID=40&md5=85b007eec7ba9027c89accd83ca6b409
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Kalderon B, Sheena V, Shachrur S, Hertz R, Bar-Tana J. Modulation by nutrients and drugs of liver acyl-CoAs analyzed by mass spectrometry. Journal of Lipid Research [Internet]. 2002;43(7):1125–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036317639&doi=10.1194%252fjlr.M200060-JLR200&partnerID=40&md5=18c1ba51aa75981dce442c90b9423f4e
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Bartoov-Shifman R, Hertz R, Wang H, Wollheim CB, Bar-Tana J, Walker MD. Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4α. Journal of Biological Chemistry [Internet]. 2002;277(29):25914–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037135622&doi=10.1074%252fjbc.M201582200&partnerID=40&md5=fdc314b6b139b2353822ed739fa0fc0c
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Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB. Ligand specificity and conformational dependence of the hepatic nuclear factor-4α (HNF-4α). Journal of Biological Chemistry [Internet]. 2002;277(27):23988–99. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037025344&doi=10.1074%252fjbc.M201241200&partnerID=40&md5=d3b0cd106d54073d0525460ce0438511
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Atkinson LL, Kelly SE, Russell JC, Bar-Tana J, Lopaschuk GD. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR:LA-cp rats. Diabetes [Internet]. 2002;51(5):1548–55. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036319122&doi=10.2337%252fdiabetes.51.5.1548&partnerID=40&md5=2a314f6979ef39272ffb9fcd4f9692ba
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Hertz R, Sheena V, Kalderon B, Berman I, Bar-Tana J. Suppression of hepatocyte nuclear factor-4α by acyl-CoA thioesters of hypolipidemic peroxisome proliferators. Biochemical Pharmacology [Internet]. 2001;61(9):1057–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035342271&doi=10.1016%2fS0006-2952%2801%2900578-0&partnerID=40&md5=7634c08b0936a35e19465ddd090e9954
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Bar-Tana J. Peroxisome proliferator-activated receptor gamma (PPARγ) activation and its consequences in humans. Toxicology Letters [Internet]. 2001;120(1–3):9–19. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035977861&doi=10.1016%2fS0378-4274%2801%2900302-2&partnerID=40&md5=713a1114cf33e760c54c03d29129f83a
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Hermesh O, Kalderon B, Berman B, Bar-Tana J. Mitochondrial protonophoric activity induced by a thyromimetic fatty acid analogue. Biochimica et Biophysica Acta - Bioenergetics [Internet]. 2000;1457(3):166–74. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034640041&doi=10.1016%2fS0005-2728%2800%2900097-9&partnerID=40&md5=0c999ac00252ac07b0ecf65e34fcd1bf
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Kalderon B, Mayorek N, Berry E, Zevit N, Bar-Tana J. Fatty acid cycling in the fasting rat. American Journal of Physiology - Endocrinology and Metabolism [Internet]. 2000;279(1 42-1):E221–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033863358&doi=10.1152%252fajpendo.2000.279.1.e221&partnerID=40&md5=6e84f19e5b0875925086bf30d3e12b9b
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Popa R, Salem L, Schwalb H, Merin G, Borman JB, Bar-Tana J. Protection by cyclosporin A from cardiac ischemia-reperfusion damage. Experimental and Clinical Cardiology [Internet]. 2000;5(2):77–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033656853&partnerID=40&md5=ba68b695feb33ee37efdf73797dd0d65
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Hertz R, Bar-Tana J. Peroxisome proliferator-activated receptor (PPAR) alpha activation and its consequences in humans. Toxicology Letters [Internet]. 1998;102–103:85–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032439396&doi=10.1016%2fS0378-4274%2898%2900290-2&partnerID=40&md5=062103e06e8c019e845e7a5d54bee076
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Bar-Tana J. Transcriptional modulation of hepatocyte nuclear factor 4a (HNF-4a) and/or peroxisome proliferator-activated receptor a (PPARa)-controlled genes by low molecular weight compounds. Expert Opinion on Therapeutic Targets [Internet]. 1998;2(1):141–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79961054075&doi=10.1517%252f14728222.2.1.141&partnerID=40&md5=0f17c41e77783acbf1c588d89a2a69db
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Russell JC, Shillabeer G, Bar-Tana J, Lau DCW, Richardson M, Wenzel LM, et al. Development of insulin resistance in the JCR:LA-cp rat: Role of triacylglycerols and effects of MEDICA 16. Diabetes [Internet]. 1998;47(5):770–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031894623&doi=10.2337%252fdiabetes.47.5.770&partnerID=40&md5=cc80e6f79aec179d8dcf88776dad7a19
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Hertz R, Magenheim J, Berman I, Bar-Tana J. Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α. Nature [Internet]. 1998;392(6675):512–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032473950&doi=10.1038%252f33185&partnerID=40&md5=85e86ba45318c8411e06a11112b889b6
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Hermesh O, Kalderon B, Bar-Tana J. Mitochondria uncoupling by a long chain fatty acyl analogue. Journal of Biological Chemistry [Internet]. 1998;273(7):3937–3742. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032512651&doi=10.1074%252fjbc.273.7.3937&partnerID=40&md5=f3d8557d1d62bf43c55d99892b7ab397
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Mayorek N, Kalderon B, Itach E, Bar-Tana J. Sensitization to insulin induced by β,β’-methyl-substituted hexadecanedioic acid (MEDICA 16) in obese Zucker rats in vivo. Diabetes [Internet]. 1997;46(12):1958–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030773514&doi=10.2337%252fdiab.46.12.1958&partnerID=40&md5=ea40f0b3d8a6d2a95d3888dc19a4b064
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Hertz R, Seckbach M, Zakin MM, Bar-Tana J. Transcriptional suppression of the transferrin gene by hypolipidemic peroxisome proliferators. Journal of Biological Chemistry [Internet]. 1996;271(1):218–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030058106&doi=10.1074%252fjbc.271.1.218&partnerID=40&md5=db7a3031117b4f18bd72644e3f369b3d
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Hertz R, Bishara-Shieban J, Bar-Tana J. Hypolipidemic Effect of Peroxisome Proliferators: Transcriptional Suppression of Apolipoprotein C-III. Annals of the New York Academy of Sciences [Internet]. 1996;804:731–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030469496&doi=10.1111%252fj.1749-6632.1996.tb18683.x&partnerID=40&md5=cff78718904180a8bdb671294a3de013
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Hertz R, Berman I, Keppler D, Bar-Tana J. Activation of gene transcription by prostacyclin analogues is mediated by the peroxisome-proliferators-activated receptor (PPAR). European Journal of Biochemistry [Internet]. 1996;235(1–2):242–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030069325&doi=10.1111%252fj.1432-1033.1996.00242.x&partnerID=40&md5=7db209329921853aae2175332dc3c702
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Hertz R, Nikodem V, Ben-Ishai A, Berman I, Bar-Tana J. Thyromimetic mode of action of peroxisome proliferators: Activation of “malic” enzyme gene transcription. Biochemical Journal [Internet]. 1996;319(1):241–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029839416&doi=10.1042%252fbj3190241&partnerID=40&md5=1180211b0162b41f1258453e48bd7781
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Brandes R, Arad R, Bar-Tana J. Inducers of adipose conversion activate transcription promoted by a peroxisome proliferators response element in 3T3-L1 cells. Biochemical Pharmacology [Internet]. 1995;50(11):1949–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029587176&doi=10.1016%2f0006-2952%2895%2902082-9&partnerID=40&md5=e7275441b3148f5d4387dc2828a90a74
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Kalderon B, Hermesh O, Bar-Tana J. Mitochondrial permeability transition is induced by in vivo thyroid hormone treatment. Endocrinology [Internet]. 1995;136(8):3552–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029129103&doi=10.1210%252fendo.136.8.7628392&partnerID=40&md5=19ee32ac16367a3f2716ff3963a71c08
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Russell JC, Amy RM, Graham SE, Dolphin PJ, Wood GO, Bar-Tana J. Inhibition of atherosclerosis and myocardial lesions in the JCR:LA-cp rat by β,β’-tetramethylhexadecanedioic acid (MEDICA 16). Arteriosclerosis, Thrombosis, and Vascular Biology [Internet]. 1995;15(7):918–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029016886&doi=10.1161%252f01.ATV.15.7.918&partnerID=40&md5=da3d60281b85616c9d8d10e15a8c6976
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Hertz R, Bishara-Shieban J, Bar-Tana J. Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III. Journal of Biological Chemistry [Internet]. 1995;270(22):13470–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028998129&doi=10.1074%252fjbc.270.22.13470&partnerID=40&md5=7c6b7d52ca02dbb1f83c4ffc83e3eb58
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Jedlitschky G, Leier I, Böhme M, Buchholz U, Bar-Tana J, Keppler D. Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent atp-dependent transport across the canalicular membrane. Biochemical Pharmacology [Internet]. 1994;48(6):1113–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027935783&doi=10.1016%2f0006-2952%2894%2990147-3&partnerID=40&md5=72e90cafe4780800790ff23dc2a66715
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HERTZ R, BERMAN I, BAR‐TANA J. Transcriptional activation by amphipathic carboxylic peroxisomal proliferators is induced by the free acid rather than the acyl‐CoA derivative. European Journal of Biochemistry [Internet]. 1994;221(1):611–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028273806&doi=10.1111%252fj.1432-1033.1994.tb18773.x&partnerID=40&md5=3ec7a261502048ded4d048d8d21c88d2
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Frenkel B, Bishara-Shieban J, Bar-Tana J. The effect of β,β’-tetramethylhexadecanedioic acid (MEDICA 16) on plasma very-low-density lipoprotein metabolism in rats: Role of apolipoprotein C-III. Biochemical Journal [Internet]. 1994;298(2):409–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028218398&doi=10.1042%252fbj2980409&partnerID=40&md5=f670256c988fb0c06d3a062cf1eaca95
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Brandes R, Arad R, Gaathon A, Bar-Tana J. Induction of adipose conversion in 3T3-L1 cells is associated with an early phosphorylation of a protein partly homologous with mouse vimentin. FEBS Letters [Internet]. 1993;333(1–2):179–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027525274&doi=10.1016%2f0014-5793%2893%2980400-O&partnerID=40&md5=a1e2bcffa8846dee5f3105bb0af09b0b
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Mayorek N, Bar-Tana J. Hypocholesterolaemic effect of ββ-methyl-substituted hexadecanedioic acid (MEDICA 16) in the male hamster. Biochemical Journal [Internet]. 1993;289(3):911–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027400294&doi=10.1042%252fbj2890911&partnerID=40&md5=0986fabc705909ed4c50679dc0255634
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Hertz R, Kalderon B, Bar-Tana J. Thyromimetic effect of peroxisome proliferators. Biochimie [Internet]. 1993;75(3–4):257–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027215754&doi=10.1016%2f0300-9084%2893%2990085-7&partnerID=40&md5=c948e322cf9914c169546ea11acfa744
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Kalderon B, Hertz R, Bar-Tana J. Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver. Endocrinology [Internet]. 1992;131(1):400–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026778138&doi=10.1210%252fendo.131.1.1612021&partnerID=40&md5=4b62689df0e075884b84a6c9747751ac
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Kalderon B, Hertz R, Bar-Tana J. Tissue selective modulation of redox and phosphate potentials by β,β′-methyl-substituted hexadecanedioic acid. Endocrinology [Internet]. 1992;131(4):1629–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026713543&doi=10.1210%252fendo.131.4.1396307&partnerID=40&md5=07f43090cf67c674268f1d026296e200
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Kalderon B, Hertz R, Bar-Tana J. Erratum: Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver (Endocrinology (1992) 131 (400-407)). Endocrinology [Internet]. 1992;131(4):1962. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026666650&partnerID=40&md5=530196ea178e01b603a8f06af26000d3
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Hertz R, Bar-Tana J. Induction of peroxisomal β-oxidation genes by retinoic acid in cultured rat hepatocytes. Biochemical Journal [Internet]. 1992;281(1):41–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026545956&doi=10.1042%252fbj2810041&partnerID=40&md5=ef234323dee0496a233680737ba16697
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Brandes R, Arad R, Bar-Tana J. The induction of adipose conversion in 3T3-L1 cells is associated with early phosphorylation of a 60-kDa nuclear protein. FEBS Letters [Internet]. 1991;285(1):63–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025760651&doi=10.1016%2f0014-5793%2891%2980725-I&partnerID=40&md5=65255780f72b91f486b8f5d25fcaeeb8
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Hertz R, Aurbach R, Hashimoto T, Bar-Tana J. Thyromimetic effect of peroxisomal proliferators in rat liver. Biochemical Journal [Internet]. 1991;274(3):745–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026093207&doi=10.1042%252fbj2740745&partnerID=40&md5=636beafd8ef90cca3ee2c0d1f26c1045
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Russell JC, Dolphin PJ, Hameed M, Stewart B, Koeslag DG, Rose-Kahn G, et al. Hypolipidemic effect of β,β’-tetramethyl hexadecanedioic acid (MEDICA 16) in hyperlipidemic JCR:LA-corpulent rats. Arteriosclerosis and Thrombosis [Internet]. 1991;11(3):602–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025735665&doi=10.1161%252f01.atv.11.3.602&partnerID=40&md5=fedd25fea79f68770b8c38fb1757833b
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Almagor M, Bar-Tana J. Retinoic acid inhibits the myristoylation of a membrane protein in HL-60 cells. Biochemical and Biophysical Research Communications [Internet]. 1990;172(2):877–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025026401&doi=10.1016%2f0006-291X%2890%2990757-E&partnerID=40&md5=7ac5aa0db59c406f063eaf98059dc8e4
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Brandes R, Arad R, Benvenisty N, Weil S, Bar-Tana J. The induction of adipose conversion by bezafibrate in 3T3-L1 cells. Synergism with dibutyryl-cAMP. BBA - Molecular Cell Research [Internet]. 1990;1054(2):219–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025111553&doi=10.1016%2f0167-4889%2890%2990244-8&partnerID=40&md5=3d7615908cdadad9d113cb3e30b56eee
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Rose-Kahn G, Bar-Tana J. Inhibition of rat liver acetyl-CoA carboxylase by β,β′-tetramethyl-substituted hexadecanedioic acid (MEDICA 16). Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1990;1042(2):259–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025141846&doi=10.1016%2f0005-2760%2890%2990018-S&partnerID=40&md5=9b9c107d26187c48b184271fbae53009
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Bar-tana J, Ben-shoshan S, Blum J, Migron Y, Hertz R, Bar-tana-rose khan G, et al. Synthesis and Hypolipidemic and Antidiabetogenic Activities of β,β,β’,β’-tetrasubstituted, Long-chain Dioic Acids. Journal of Medicinal Chemistry [Internet]. 1989;32(9):2072–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024433742&doi=10.1021%252fjm00129a010&partnerID=40&md5=b82a77e7891535f3760d731743691413
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Rosen G, Bar-Tana J. Fatty acyl coupled catalase. Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular [Internet]. 1989;994(3):264–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024546347&doi=10.1016%2f0167-4838%2889%2990303-8&partnerID=40&md5=a1ba13a780f73f8106951a32b115862e
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Mayorek N, Bar-Tana J. Lipid synthesis in permeabilized cultured rat hepatocytes. Journal of Biological Chemistry [Internet]. 1989;264(8):4450–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024506453&partnerID=40&md5=8f6d62e81b198af7bf333d6222392993
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MAYOREK N, GRINSTEIN I, BAR‐TANA J. Triacylglycerol synthesis in cultured rat hepatocytes: The rate‐limiting role of diacylglycerol acyltransferase. European Journal of Biochemistry [Internet]. 1989;182(2):395–400. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024351939&doi=10.1111%252fj.1432-1033.1989.tb14844.x&partnerID=40&md5=3d36469fef338a4f138e1b5f8c43b382
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Tzur R, Smith E, Bar-Tana J. Adipose reduction by β,β’-tetramethyl-substituted hexadecanedioic acid( MEDICA 16). International Journal of Obesity [Internet]. 1989;13(3):313–26. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024312851&partnerID=40&md5=91571e0e04b8326ff536cf27d215d3c3
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Hertz R, Bar-Tana J, Sujatta M, Pill J, Schmidt FH, Fahimi HD. The induction of liver peroxisomal proliferation by β,β′-methyl-substituted hexadecanedioic acid (MEDICA 16). Biochemical Pharmacology [Internet]. 1988;37(19):3571–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023714144&doi=10.1016%2f0006-2952%2888%2990387-5&partnerID=40&md5=a10c92682065672eeedde7960225951b
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Tzur R, Rose-Kahn G, Adler JH, Bar-Tana J. Hypolipidemic, antiobesity, and hypoglycemic-hypoinsulinemic effects of β,β’-methyl-substituted hexadecanedioic acid in sand rats. Diabetes [Internet]. 1988;37(12):1618–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024205501&doi=10.2337%252fdiab.37.12.1618&partnerID=40&md5=c2181a2642aed5a1dc6af3db696e83b5
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Bar-Tana J, Rose-Kahn G, Frenkel B, Shafer Z, Fainaru M. Hypolipidemic effect of β,β’-methyl-substituted hexadecanedioic acid (MEDICA 16) in normal and nephrotic rats. Journal of Lipid Research [Internet]. 1988;29(4):431–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023949437&partnerID=40&md5=268a75c67c2773619ff23fa8ea76beb9
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Frenkel B, Mayorek N, Hertz R, Bar-Tana J. The hypochylomicronemic effect of β,β’-methyl-substituted hexadecanedioic acid (MEDICA 16) is mediated by a decrease in apolipoprotein C-III. Journal of Biological Chemistry [Internet]. 1988;263(17):8491–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023937480&partnerID=40&md5=f77d6130945ce058e33836f744288b28
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Hertz R, Bar-Tana J. The acylation of proteins by xenobiotic amphipatic carboxylic acids in cultured rat hepatocytes. Biochemical Journal [Internet]. 1988;254(1):39–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023773044&doi=10.1042%252fbj2540039&partnerID=40&md5=34183b9e2beefad3e7882552b3c8bf81
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Brandes R, Hertz R, Arad R, Naishtat S, Weil S, Bar-Tana J. Adipocyte conversion of cultured 3T3-Ll preadipocytes by bezafibrate. Life Sciences [Internet]. 1987;40(10):935–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023137170&doi=10.1016%2f0024-3205%2887%2990312-2&partnerID=40&md5=202b7516fcdb5b986077688edeb3041d
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Hertz R, Bar-Tana J. Increased response to peroxisomal proliferators in starved rats. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1987;917(1):57–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023082847&doi=10.1016%2f0005-2760%2887%2990283-9&partnerID=40&md5=3cdc951b10b11bf1f5183d76e73a2ef4
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Hertz R, Bar-Tana J. Prevention of peroxisomal proliferation by carnitine palmitoyltransferase inhibitors in cultured rat hepatocytes and in vivo. Biochemical Journal [Internet]. 1987;245(2):387–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023263571&doi=10.1042%252fbj2450387&partnerID=40&md5=48bbdbeab97e31c55f38da2aa5e0953e
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Hertz R, Arnon J, Hoter A, Shouval D, Bar-Tana J. Clofibrate does not induce peroxisomal proliferation in human hepatoma cell lines PLC/PRF/5 and SK-HEP-1. Cancer Letters [Internet]. 1987;34(3):263–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023127206&doi=10.1016%2f0304-3835%2887%2990176-5&partnerID=40&md5=e199b5cd41c190f84fc7ed9554a9849d
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Migron Y, Blum J, Bar-Tana J. A facile synthesis of α,α,ω,ω-tetrahalo-α,ω-dicarboxylic esters. Tetrahedron [Internet]. 1987;43(2):361–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0013582405&doi=10.1016%2fS0040-4020%2801%2989964-6&partnerID=40&md5=0f0617638ee3f217f9ca588e01cd5510
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Brandes R, Arad R, Bar-Tana J. Adipose conversion of cultured rat primary preadipocytes by hypolipidemic drugs. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1986;877(2):314–21. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022486172&doi=10.1016%2f0005-2760%2886%2990309-7&partnerID=40&md5=b46b7948413508191a35fe5fe1b4e5ad
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Hertz R, Bar-Tana J. Reductive repression in Escherichia coli K-12 is mediated by oxygen radicals. Archives of Biochemistry and Biophysics [Internet]. 1986;250(1):54–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022794944&doi=10.1016%2f0003-9861%2886%2990701-0&partnerID=40&md5=f9e8626d7fb3c8f7625b9cafd14a64eb
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Bar-Tana J, Rose-Kahn G, Srebnik M. Inhibition of lipid synthesis by ββ’-tetramethyl-substituted, C14-C22, α,ω-dicarboxylic acids in the rat in vivo. Journal of Biological Chemistry [Internet]. 1985;260(14):8404–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022256692&partnerID=40&md5=a89d2172dc7c76ce2f025fceab268c6c
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Hertz R, Arnon J, Bar-Tana J. The effect of bezafibrate and long-chain fatty acids on peroxisomal activities in cultured rat hepatocytes. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1985;836(2):192–200. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022358190&doi=10.1016%2f0005-2760%2885%2990066-9&partnerID=40&md5=c412078b3e6ad89e7980ac5c03dbcc57
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Brandes R, Mayorek N, Berry E, Arad R, Bar-Tana J. The specificity of triacylglycerol synthesis for medium-chain fatty acids in rat and human adipose preparations. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1985;836(1):63–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022363481&doi=10.1016%2f0005-2760%2885%2990220-6&partnerID=40&md5=f6ffcbd90631d862c0295a1e6780553a
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Mayorek N, Bar-Tana J. Inhibition of diacylglycerol acyltransferase by 2-bromooctanoate in cultured rat hepatocytes. Journal of Biological Chemistry [Internet]. 1985;260(11):6528–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021853150&partnerID=40&md5=6e7366c4cd5aa00e43c6c9d4f15c4541
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Rose-Kahn G, Bar-Tana J. Inhibition of lipid synthesis by ββ’-tetramethyl-substituted, C14-C22, α,ω-dicarboxylic acids in cultured rat hepatocytes. Journal of Biological Chemistry [Internet]. 1985;260(14):8411–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021812755&partnerID=40&md5=a86d6b22afd4e45160d858e4c8830455
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Rosen G, Bar-Tana J. Sepharose-stearate as substrate for rat liver long-chain fatty acyl-CoA synthetase. Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular [Internet]. 1983;743(1):121–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021114082&doi=10.1016%2f0167-4838%2883%2990425-9&partnerID=40&md5=c8a436532caa87560b0a6fcf5ad9a28c
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Mayorek N, Bar Tana J. Medium chain fatty acids as specific substrates for diglyceride acyltransferase in cultured hepatocytes. Journal of Biological Chemistry [Internet]. 1983;258(11):6789–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020576551&partnerID=40&md5=7f815dbd0dfa620f4b1601efcbcee38d
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Hertz R, Bar-Tana J. Modulation of the 3′,5′-cyclic AMP content by the respiration rate in E. coli K-12. Archives of Biochemistry and Biophysics [Internet]. 1982;213(1):193–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020050273&doi=10.1016%2f0003-9861%2882%2990455-6&partnerID=40&md5=9b8ed2fc59a00dbcfac63168402fc6f2
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Brandes R, Arad R, Bar-Tana J. Translocation of long chain fatty acids into lecithin liposomes containing the long chain fatty acyl-CoA synthetase. FEBS Letters [Internet]. 1981;123(2):295–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019888807&doi=10.1016%2f0014-5793%2881%2980312-2&partnerID=40&md5=74d703ccc4fc63522a3557bae79130da
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Almagor M, Ron A, Bar‐Tana J. Chemotaxis in Tetrahymena thermophila. Cell Motility [Internet]. 1981;1(2):261–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019857709&doi=10.1002%252fcm.970010208&partnerID=40&md5=639819927e240eb134fcdf143b71e288
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Howlett BJ, Bar-Tana J. Polyprenyl p-hydroxybenzoate carboxylase in flagellation of Salmonella typhimurium. Journal of Bacteriology [Internet]. 1980;143(2):644–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018946746&partnerID=40&md5=fd7cb6c280f69e8735a063d35ceaf5fd
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Bar-Tana J, Howlett BJ, Hertz R. Ubiquinone synthetic pathway in flagellation of Salmonella typhimurium. Journal of Bacteriology [Internet]. 1980;143(2):637–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018944059&partnerID=40&md5=ae40c212601a2fbd6c638bc94293a440
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Rose G, Bar-Tana J, Shapiro B. Palmitoyl coenzyme a synthetase activation by uncomplexed ATP. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1979;573(1):126–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018802535&doi=10.1016%2f0005-2760%2879%2990179-6&partnerID=40&md5=593d2da1707963bb0f63afe1fdfe60c5
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Hertz R, Bar-Tana J. Anaerobic electron transport in anaerobic flagellum formation in Escherichia coli. Journal of Bacteriology [Internet]. 1977;132(3):1034–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017763648&partnerID=40&md5=1c31a444362fb4be5225ea032c1f991f
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Maes E, Bar-Tana J. Rat liver microsomal palmitoyl-CoA synthetase: Subunit structure. BBA - Enzymology [Internet]. 1977;480(2):527–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017581254&doi=10.1016%2f0005-2744%2877%2990049-3&partnerID=40&md5=88abcffc9868bcc483aca3585c34fd74
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Almagor M, Bar-Tana J, Ron A. Chemotaxis in Tetrahymena. Journal of Cell Biology [Internet]. 1977;75(2 II). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-18844465906&partnerID=40&md5=a14c2265493a9d144dd4fbacc09beb82
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Bar-Tana J, Rose G, Shapiro B. [15] Long-chain fatty acyl-CoA synthetase from rat liver microsomes. Methods in Enzymology [Internet]. 1975;35(C):117–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016420266&doi=10.1016%2f0076-6879%2875%2935146-X&partnerID=40&md5=fce422d1ec4a94d717a40363ac4ab071
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Rose IA, O’Connell EL, Litwin S, Bar Tana J. Determination of the rate of hexokinase glucose dissociation by the isotope trapping method. Journal of Biological Chemistry [Internet]. 1974;249(16):5163–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0016301992&partnerID=40&md5=59ad9772324373fbddb3b3a2e6bcdddd
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Bar Tana J, Cleland WW. Rabbit muscle phosphofructokinase. II. Product and dead end inhibition. Journal of Biological Chemistry [Internet]. 1974;249(4):1271–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015966395&partnerID=40&md5=e00bdbbcd6231950fb5aa303b0b98e0a
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Bar Tana J, Cleland WW. Rabbit muscle phosphofructokinase. I. Anomeric specificity; initial velocity kinetics. Journal of Biological Chemistry [Internet]. 1974;249(4):1263–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015953849&partnerID=40&md5=530de5e97f82d38321da32665b701eb5
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Bar Tana J, Rose G, Shapiro B. Palmitoyl coenzyme A synthetase. Isolation of an enzyme bound intermediate. Biochemical Journal [Internet]. 1973;135(3):411–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015802872&doi=10.1042%252fbj1350411&partnerID=40&md5=9b269449c1e9454c782975aa71153237
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Bar-Tana J, Rose G. Rat liver microsomal palmitoyl-coenzyme A synthetase. Structural properties. The Biochemical journal [Internet]. 1973;131(3):443–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015598714&doi=10.1042%252fbj1310443&partnerID=40&md5=bfc0ed4a6c960c899c4e6cb69bbeeb03
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Bar-Tana J, Rose G, Brandes R, Shapiro B. Palmitoyl-coenzyme A synthetase. Mechanism of reaction. The Biochemical journal [Internet]. 1973;131(2):199–209. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0015580995&doi=10.1042%252fbj1310199&partnerID=40&md5=f5aba2ad6dbd75940a808fbdcbce5266
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