1.            Shaul, D. et al. Real-time influence of intracellular acidification and Na+/H+ exchanger inhibition on in-cell pyruvate metabolism in the perfused mouse heart: A 31P-NMR and hyperpolarized 13C-NMR study. NMR Biomed. 36, (2023).

2.            Rooney, C. H. E. et al. Directly Bound Deuterons Increase X-Nuclei Hyperpolarization using Dynamic Nuclear Polarization. ChemPhysChem 24, (2023).

3.            Shaul, D. et al. Investigating Cardiac Metabolism in the Isolated Perfused Mouse Heart with Hyperpolarized [1-13C]Pyruvate and13C/31P NMR Spectroscopy. J. Vis. Exp. 2023, (2023).

4.            Gamliel, A., Shaul, D., Gomori, J. M. & Katz-Brull, R. Signal enhancement of hyperpolarized 15N sites in solution—increase in solid-state polarization at 3.35 T and prolongation of relaxation in deuterated water mixtures. NMR Biomed. 35, (2022).

5.            Shaul, D. et al. Accumulation of 3-aminopropylphosphonate in the ex vivo brain observed by phosphorus-31 nuclear magnetic resonance. NMR Biomed. 35, (2022).

6.            Katz-Brull, R. Tolerance of Rodents to an Intravenous Bolus Injection of Sodium Nitrate in a High Concentration. Biology (Basel). 11, (2022).

7.            Grieb, B. et al. Curbing action potential generation or ATP-synthase leads to a decrease in in-cell pyruvate dehydrogenase activity in rat cerebrum slices. Sci. Rep. 11, (2021).

8.            Sapir, G., Steinberg, D. J., Aqeilan, R. I. & Katz-Brull, R. Real-time non-invasive and direct determination of lactate dehydrogenase activity in cerebral organoids—a new method to characterize the metabolism of brain organoids? Pharmaceuticals 14, (2021).

9.            Shaul, D. et al. The metabolic representation of ischemia in rat brain slices: A hyperpolarized 13C magnetic resonance study. NMR Biomed. 34, (2021).

10.          Sapir, G. et al. Ldh and pdh activities in the ischemic brain and the effect of reperfusion—an ex vivo mr study in rat brain slices using hyperpolarized [1-13 c]pyruvate. Metabolites 11, (2021).

11.          Lev-Cohain, N. et al. Differentiation of Heterogeneous Mouse Liver from HCC by Hyperpolarized 13C Magnetic Resonance. Sci 3, (2021).

12.          Shaul, D. et al. Correlation between lactate dehydrogenase/pyruvate dehydrogenase activities ratio and tissue pH in the perfused mouse heart: A potential noninvasive indicator of cardiac pH provided by hyperpolarized magnetic resonance. NMR Biomed. 34, (2021).

13.          Uppala, S. et al. Observation of glucose-6-phosphate anomeric exchange in real-time using dDNP hyperpolarised NMR. RSC Adv. 10, 41197–41201 (2020).

14.          Kreis, F., Wright, A. J., Somai, V., Katz-Brull, R. & Brindle, K. M. Increasing the sensitivity of hyperpolarized [15N2]urea detection by serial transfer of polarization to spin-coupled protons. Magn. Reson. Med. 84, 1844–1856 (2020).

15.          Lev-Cohain, N. et al. Erratum to: Real-time ALT and LDH activities determined in viable precision-cut mouse liver slices using hyperpolarized [1- 13 C]pyruvate-Implications for studies on biopsied liver tissues (NMR in Biomedicine, (2019), 32, 2, (e4043), 10.1002/nbm.4043). NMR Biomed. 33, (2020).

16.          Harris, T. et al. The Effect of Gadolinium Doping in [13C6,2H7]Glucose Formulations on 13C Dynamic Nuclear Polarization at 3.35 T. ChemPhysChem 21, 251–256 (2020).

17.          Harris, T. et al. Hyperpolarized product selective saturating-excitations for determination of changes in metabolic reaction rates in real-time. NMR Biomed. 33, (2020).

18.          Sapir, G. et al. [13C6,D8]2-deoxyglucose phosphorylation by hexokinase shows selectivity for the β-anomer. Sci. Rep. 9, (2019).

19.          Uppala, S. et al. 1H-decoupling and Isotopic Labeling for the Measurement of the Longitudinal Relaxation Time of Hyperpolarized 13C-Methylenes in Choline Analogs. Isr. J. Chem. 59, 1014–1019 (2019).

20.          Adler-Levy, Y. et al. In-cell determination of lactate dehydrogenase activity in a luminal breast cancer model – ex vivo investigation of excised xenograft tumor slices using dDNP hyperpolarized [1-13C]pyruvate. Sensors (Switzerland) 19, (2019).

21.          Gamliel, A. et al. Hyperpolarized [ 15 N]nitrate as a potential long lived hyperpolarized contrast agent for MRI. J. Magn. Reson. 299, 188–195 (2019).

22.          Lev-Cohain, N. et al. Real-time ALT and LDH activities determined in viable precision-cut mouse liver slices using hyperpolarized [1-13C]pyruvate—Implications for studies on biopsied liver tissues. NMR Biomed. 32, (2019).

23.          Harris, T. et al. Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-13C]pyruvate. Sci. Rep. 8, (2018).

24.          Nardi-Schreiber, A. et al. Correction: Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions (Nature Communications (2017) DOI: 10.1038/s41467-017-00364-3). Nat. Commun. 9, (2018).

25.          Harris, T., Gamliel, A., Sosna, J., Gomori, J. M. & Katz-Brull, R. Impurities of [1-13C]Pyruvic Acid and a Method to Minimize Their Signals for Hyperpolarized Pyruvate Metabolism Studies. Appl. Magn. Reson. 49, 1085–1098 (2018).

26.          Harris, T. et al. Long-lived 15N Hyperpolarization and Rapid Relaxation as a Potential Basis for Repeated First Pass Perfusion Imaging – Marked Effects of Deuteration and Temperature. ChemPhysChem 19, 2148–2152 (2018).

27.          Hövener, J.-B. et al. Parahydrogen-Based Hyperpolarization for Biomedicine. Angew. Chemie - Int. Ed. 57, 11140–11162 (2018).

28.          Nardi-Schreiber, A. et al. Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions. Nat. Commun. 8, (2017).

29.          Grigoletto, J. et al. Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss. Acta Neuropathol. Commun. 5, 37 (2017).

30.          Nardi-Schreiber, A. et al. Defective ATP breakdown activity related to an: ENTPD1 gene mutation demonstrated using 31P NMR spectroscopy. Chem. Commun. 53, 9121–9124 (2017).

31.          Banne, E. et al. Transaldolase deficiency: A new case expands the phenotypic spectrum. JIMD Reports vol. 26 31–36 (2016).

32.          Gamliel, A., Chendler, N., Moshe Gomori, J., Sosna, J. & Katz-Brull, R. The Sensitivity of Phosphocholine 13C Chemical Shifts to pH. Appl. Magn. Reson. 47, 111–120 (2016).

33.          Friesen-Waldner, L. J. et al. Hyperpolarized choline as an MR imaging molecular probe: Feasibility of in vivo imaging in a rat model. J. Magn. Reson. Imaging 41, 917–923 (2015).

34.          Friesen-Waldner, L. J. et al. Direct enzyme-substrate affinity determination by real-time hyperpolarized 13C-MRS. Chem. Commun. 50, 13801–13804 (2014).

35.          Allouche-Arnon, H., Arazi-Kleinman, T., Fraifeld, S., Uziely, B. & Katz-Brull, R. MRS of the Breast. in Comprehensive Biomedical Physics vol. 3 299–314 (Elsevier, 2014).

36.          Allouche-Arnon, H. et al. Quantification of rate constants for successive enzymatic reactions with DNP hyperpolarized MR. NMR Biomed. 27, 656–662 (2014).

37.          Allouche-Arnon, H., Gamliel, A., Sosna, J., Moshe Gomori, J. & Katz-Brull, R. In vitro visualization of betaine aldehyde synthesis and oxidation using hyperpolarized magnetic resonance spectroscopy. Chem. Commun. 49, 7076–7078 (2013).

38.          Allouche-Arnon, H. et al. In vivo magnetic resonance imaging of glucose - initial experience. Contrast Media Mol. Imaging 8, 72–82 (2013).

39.          Allouche-Arnon, H., Lerche, M. H., Karlsson, M., Lenkinski, R. E. & Katz-Brull, R. Deuteration of a molecular probe for DNP hyperpolarization - A new approach and validation for choline chloride. Contrast Media Mol. Imaging 6, 499–506 (2011).

40.          Allouche-Arnon, H. et al. A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis. Contrast Media Mol. Imaging 6, 139–147 (2011).

41.          Gamliel, A. et al. An Apparatus for Production of Isotopically and Spin-Enriched Hydrogen for Induced Polarization Studies. Appl. Magn. Reson. 39, 329–345 (2010).

42.          Edvardson, S. et al. L-arginine:glycine amidinotransferase (AGAT) deficiency: Clinical presentation and response to treatment in two patients with a novel mutation. Mol. Genet. Metab. 101, 228–232 (2010).

43.          Lima, M. A. et al. Remission of progressive multifocal leukoencephalopathy and primary central nervous system lymphoma in an HIV-infected patient. Eur. J. Neurol. 14, 598–602 (2007).

44.          Katz-Brull, R., Alsop, D. C., Marquis, R. P. & Lenkinski, R. E. Limits on activation-induced temperature and metabolic changes in the human primary visual cortex. Magn. Reson. Med. 56, 348–355 (2006).

45.          Katz-Brull, R., Koudinov, A. R. & Degani, H. Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy. Brain Res. 1048, 202–210 (2005).

46.          Katz-Brull, R. et al. Decreases in free cholesterol and fatty acid unsaturation in renal cell carcinoma demonstrated by breath-hold magnetic resonance spectroscopy. Am. J. Physiol. - Ren. Physiol. 288, F637–F641 (2005).

47.          Katz-Brull, R., Lenkinski, R. E., Du Pasquier, R. A. & Koralnik, I. J. Elevation of myoinositol is associated with disease containment in progressive multifocal leukoencephalopathy. Neurology 63, 897–900 (2004).

48.          Katz-Brull, R. & Lenkinski, R. E. Frame-by-Frame PRESS 1H-MRS of the Brain at 3 T: The Effects of Physiological Motion. Magn. Reson. Med. 51, 184–187 (2004).

49.          Katz-Brull, R., Rofsky, N. M. & Lenkinski, R. E. Breathhold abdominal and thoracic proton MR spectroscopy at 3T. Magn. Reson. Med. 50, 461–467 (2003).

50.          Katz-Brull, R., Koudinov, A. R. & Degani, H. Choline in the aging brain. Brain Res. 951, 158–165 (2002).

51.          Katz-Brull, R., Lavin, P. T. & Lenkinski, R. E. Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions. J. Natl. Cancer Inst. 94, 1197–1203 (2002).

52.          Katz-Brull, R., Seger, D., Rivenson-Segal, D., Rushkin, E. & Degani, H. Metabolic markers of breast cancer: Enhanced choline metabolism and reduced choline-ether-phospholipid synthesis. Cancer Res. 62, 1966–1970 (2002).

53.          Katz-Brull, R., Margalit, R. & Degani, H. Differential routing of choline in implanted breast cancer and normal organs. Magn. Reson. Med. 46, 31–38 (2001).

54.          Katz-Brull, R., Margalit, R., Bendel, P. & Degani, H. Choline metabolism in breast cancer; 2H-, 13C- and 31P-NMR studies of cells and tumors. Magn. Reson. Mater. Physics, Biol. Med. 6, 44–52 (1998).

55.          Katz-Brull, R. & Degani, H. Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method. Anticancer Res. 16, 1375–1379 (1996).