Last updated June 2021 - Hadassah Medical Center
1. Gileles-Hillel, A., Bhattacharjee, R., Gorelik, M. & Narang, I. Advances in Sleep-Disordered Breathing in Children. Clin. Chest Med. 45, 651–662 (2024).
2. Guzikevits, M. et al. Sex bias in pain management decisions. Proc. Natl. Acad. Sci. U. S. A. 121, (2024).
3. Levin, S., Mayer, D., Puius, Y. A., Arora, S. & Gileles-Hillel, A. Things We Do for No ReasonTM: Routine respiratory pathogen panels for emergency department and hospitalized patients. J. Hosp. Med. (2024) doi:10.1002/jhm.13365.
4. Yelov, L., Reiter, J., Cruz, M. M. E. & Gileles-Hillel, A. The association of obstructive sleep apnea and behavioral insomnia in children ages 10 and under. J. Clin. Sleep Med. 20, 245–251 (2024).
5. Cohen-Cymberknoh, M. et al. Changes in Sleep in Children and Adults with Cystic Fibrosis and Primary Ciliary Dyskinesia over Time and after CFTR Modulator Therapy. J. Clin. Med. 12, (2023).
6. Sadras, I. et al. Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation. J. Cyst. Fibros. 22, 1062–1069 (2023).
7. Adler-Haltovsky, T., Gileles-Hillel, A., Erlichman, I. & Eventov-Friedman, S. Changes in ventilation modes in the last decade and their impact on the prevalence of bronchopulmonary dysplasia in preterm infants. Pediatr. Pulmonol. 58, 1959–1966 (2023).
8. Reiter, J. et al. Sleep disorders in children with celiac disease: a prospective study. J. Clin. Sleep Med. 19, 591–594 (2023).
9. Gileles-Hillel, A. et al. The clinical yield of bronchoscopy in the management of cystic fibrosis: A retrospective multicenter study. Pediatr. Pulmonol. 58, 500–506 (2023).
10. Dahan, T. et al. Chronic Intermittent Hypoxia during Sleep Causes Browning of Interscapular Adipose Tissue Accompanied by Local Insulin Resistance in Mice. Int. J. Mol. Sci. 23, (2022).
11. Gileles-Hillel, A. et al. The utility of glucose area under the curve from the oral glucose tolerance test as a screening tool for cystic fibrosis-related diabetes. Pediatr. Pulmonol. 57, 2774–2780 (2022).
12. Reiter, J., Breuer, O., Cohen-Cymberknoh, M., Forno, E. & Gileles-Hillel, A. Sleep in children with cystic fibrosis: More under the covers. Pediatr. Pulmonol. 57, 1944–1951 (2022).
13. Reiter, J., Ramagopal, M., Gileles-Hillel, A. & Forno, E. Sleep disorders in children with asthma. Pediatr. Pulmonol. 57, 1851–1859 (2022).
14. Choshen-Hillel, S. et al. Physicians prescribe fewer analgesics during night shifts than day shifts. Proc. Natl. Acad. Sci. U. S. A. 119, (2022).
15. Gileles-Hillel, A. & Dahan, T. Intermittent by day, sustained by night - the worst of both hypoxias? Sleep 45, (2022).
16. Israeli, T. et al. Respiratory physiotherapy in patients with cystic fibrosis and upper limb deep vein thrombosis. Pediatr. Pulmonol. 57, 1552–1554 (2022).
17. Biro, O., Gileles-Hillel, A., Dor-Wollman, T., Eisenstein, E. M. & Berkun, Y. Neurological and neurodevelopmental symptoms in children with familial Mediterranean fever and their siblings. Eur. J. Pediatr. 181, 973–978 (2022).
18. van der Vaart, J. et al. Modelling of primary ciliary dyskinesia using patient-derived airway organoids. EMBO Rep. 22, (2021).
19. Choshen-Hillel, S. & Gileles-Hillel, A. A wake-up call: Time to raise physicians’ awareness of the consequences of fatigue. Med. Educ. 55, 1342–1344 (2021).
20. Paltiel, O. et al. Academic activism on behalf of children during the COVID-19 pandemic in Israel; beyond public health advocacy. Isr. J. Health Policy Res. 10, (2021).
21. Bar-Or, R. L. et al. Associations of exposure to nitrogen oxides with prevalent asthma and other atopic diseases in Israel. Environ. - MDPI 8, (2021).
22. Khalyfa, A. et al. Heterogeneity of melanoma cell responses to sleep apnea-derived plasma exosomes and to intermittent hypoxia. Cancers (Basel). 13, (2021).
23. Grunewald, M. et al. Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span. Science 373, (2021).
24. Kaditis, A. G. et al. Effects of the COVID-19 lockdown on sleep duration in children and adolescents: A survey across different continents. Pediatr. Pulmonol. 56, 2265–2273 (2021).
25. Cohen-Cymberknoh, M. et al. How abnormal is the normal? Clinical characteristics of CF patients with normal FEV1. Pediatr. Pulmonol. 56, 2007–2013 (2021).
26. Barak-Corren, Y., Barak-Corren, N., Gileles-Hillel, A. & Heiman, E. The effect of C-reactive protein on chest X-ray interpretation: A decision-making experiment among pediatricians. Pediatr. Pulmonol. 56, 1644–1650 (2021).
27. Gileles-Hillel, A. et al. Betamethasone versus dexamethasone for inpatient preschool wheezing—A case-control study. Pediatr. Pulmonol. 56, 875–882 (2021).
28. Raz, R. et al. Associations between exposure to industrial air pollution and prevalence of asthma and atopic diseases in haifa bay area. Atmosphere (Basel). 12, (2021).
29. Kerem, E. et al. Ivacaftor in People with Cystic Fibrosis and a 3849110kb C→T or D1152H Residual Function Mutation. Ann. Am. Thorac. Soc. 18, 433–441 (2021).
30. Gileles-Hillel, A. Sickle cell disease and obstructive sleep apnea-bad news for the brain. Sleep 44, (2021).
31. Choshen-Hillel, S. et al. Acute and chronic sleep deprivation in residents: Cognition and stress biomarkers. Med. Educ. 55, 174–184 (2021).
32. Mandelkorn, U. et al. Escalation of sleep disturbances amid the COVID-19 pandemic: A cross-sectional international study. J. Clin. Sleep Med. 17, 45–53 (2021).
33. Ryan, S. et al. Understanding the pathophysiological mechanisms of cardiometabolic complications in obstructive sleep apnoea: Towards personalised treatment approaches. Eur. Respir. J. 56, (2020).
34. Yogev, D. et al. Hijab pin ingestions. Pediatrics 145, (2020).
35. Reiter, J. et al. Sleep disorders in cystic fibrosis: A systematic review and meta-analysis. Sleep Med. Rev. 51, (2020).
36. Gileles-Hillel, A. et al. Whole-exome sequencing accuracy in the diagnosis of primary ciliary dyskinesia. ERJ Open Res. 6, (2020).
37. Lavi, E., Gileles-Hillel, A. & Zangen, D. Somatic growth in cystic fibrosis. Curr. Opin. Endocrinol. Diabetes Obes. 27, 38–46 (2020).
38. Sadras, I. et al. Prematurity as a risk factor of sleep-disordered breathing in children younger than two years: A retrospective case-control study. J. Clin. Sleep Med. 15, 1731–1736 (2019).
39. Gross, I. et al. Giant lung cysts following necrotizing pneumonia: Resolution with conservative treatment. Pediatr. Pulmonol. 54, 901–906 (2019).
40. Cohen-Cymberknoh, M., Atia, O., Gileles-Hillel, A., Kerem, E. & Reiter, J. Sleep disorders in patients with primary ciliary dyskinesia, cystic fibrosis with and without pancreatic insufficiency. Respir. Med. 151, 96–101 (2019).
41. Palma, J.-A., Gileles-Hillel, A., Norcliffe-Kaufmann, L. & Kaufmann, H. Chemoreflex failure and sleep-disordered breathing in familial dysautonomia: Implications for sudden death during sleep. Auton. Neurosci. Basic Clin. 218, 10–15 (2019).
42. Lavi, E. et al. Pyogenic sacroiliitis in children: don’t forget the very young. Eur. J. Pediatr. 178, 575–579 (2019).
43. Gileles-Hillel, A., Erlichman, I. & Reiter, J. Apnea of Prematurity: An Update. J. Child Sci. 9, E50–E58 (2019).
44. Khalyfa, A. et al. Exosomes and metabolic function in mice exposed to alternating dark-light cycles mimicking night shift work schedules. Front. Physiol. 8, (2017).
45. Khalyfa, A. et al. Activation of the integrated stress response and metabolic dysfunction in a murine model of sleep apnea. Am. J. Respir. Cell Mol. Biol. 57, 477–486 (2017).
46. Cohen-Cymberknoh, M. et al. Clinical impact of Pseudomonas aeruginosa colonization in patients with Primary Ciliary Dyskinesia. Respir. Med. 131, 241–246 (2017).
47. Gozal, D. et al. Visceral white adipose tissue after chronic intermittent and sustained hypoxia in mice. Am. J. Respir. Cell Mol. Biol. 56, 477–487 (2017).
48. Gileles-Hillel, A. et al. Prolonged exposures to intermittent hypoxia promote visceral white adipose tissue inflammation in a murine model of severe sleep apnea: Effect of normoxic recovery. Sleep 40, (2017).
49. Cortese, R. et al. Aorta macrophage inflammatory and epigenetic changes in a murine model of obstructive sleep apnea: Potential role of CD36. Sci. Rep. 7, (2017).
50. Akbarpour, M. et al. Altered CD8+ t-cell lymphocyte function and tc1 cell stemness contribute to enhanced malignant tumor properties in murine models of sleep apnea. Sleep 40, (2017).
51. Gemel, J. et al. Intermittent hypoxia causes NOX2-dependent remodeling of atrial connexins. BMC Cell Biol. 18, (2017).
52. Almendros, I. et al. Tumor Cell Malignant Properties Are Enhanced by Circulating Exosomes in Sleep Apnea. Chest 150, 1030–1041 (2016).
53. Poroyko, V. A. et al. Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice. Sci. Rep. 6, (2016).
54. Khalyfa, A., Gileles-Hillel, A. & Gozal, D. The Challenges of Precision Medicine in Obstructive Sleep Apnea. Sleep Med. Clin. 11, 213–226 (2016).
55. Gileles-Hillel, A., Kheirandish-Gozal, L. & Gozal, D. Biological plausibility linking sleep apnoea and metabolic dysfunction. Nat. Rev. Endocrinol. 12, 290–298 (2016).
56. Khalyfa, A. et al. Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation. Oncotarget 7, 54676–54690 (2016).
57. Gileles-Hillel, A., Kheirandish-Gozal, L. & Gozal, D. Hemoglobinopathies and sleep - The road less traveled. Sleep Med. Rev. 24, 57–70 (2015).
58. Gileles-Hillel, A. et al. Association of chronic Candida albicans respiratory infection with a more severe lung disease in patients with cystic fibrosis. Pediatr. Pulmonol. 50, 1082–1089 (2015).
59. Alkhouri, N. et al. Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea. Sleep Med. 16, 1031–1035 (2015).
60. Kheirandish-Gozal, L. et al. Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study. Int. J. Obes. 39, 1094–1100 (2015).
61. Gileles-Hillel, A., Philby, M. F. & Lapping-Carr, G. Insights into selected aspects of pediatric sleep medicine. Am. J. Respir. Crit. Care Med. 191, 1459–1461 (2015).
62. Almendros, I. et al. Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: Effect of tumor microenvironment. Cancer Lett. 361, 233–239 (2015).
63. Carreras, A. et al. Chronic sleep fragmentation induces endothelial dysfunction and structural vascular changes in mice. Sleep 37, 1817–1824 (2014).
64. Gileles-Hillel, A. et al. Early intermittent hypoxia induces proatherogenic changes in aortic wall macrophages in a murine model of obstructive sleep apnea. Am. J. Respir. Crit. Care Med. 190, 958–961 (2014).
65. Gileles-Hillel, A. et al. Inflammatory markers and obstructive sleep apnea in obese children: The NANOS study. Mediators Inflamm. 2014, (2014).
66. Cohen-Cymberknoh, M. et al. Differences in disease expression between primary ciliary dyskinesia and cystic fibrosis with and without pancreatic insufficiency. Chest 145, 738–744 (2014).
67. Milgrom, Y., Goldman, G., Gileles Hillel, A., Pojurovsky, S. & Ackerman, Z. Tuberculosis: A rare cause of peri-anal disease. Isr. Med. Assoc. J. 15, 782–783 (2013).
68. Simanovsky, N., Gileles-Hillel, A., Frenkel, R., Shosayov, D. & Hiller, N. Correlation between computed tomography expression of pulmonary hypertension and severity of lung disease in cystic fibrosis patients. J. Thorac. Imaging 28, 383–387 (2013).
69. Hiller, N., Schor-Bardach, R., Gileles-Hillel, A., Stroumsa, D. & Simanovsky, N. CT appearance of the pelvis after Cesarean delivery-what is considered normal? Clin. Imaging 37, 514–519 (2013).
70. Simanovsky, N. et al. Differences in the pattern of structural abnormalities on CT scan in patients with cystic fibrosis and pancreatic sufficiency or insufficiency. Chest 144, 208–214 (2013).