Skip to Main Content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

The Faculty of Medicine - Microbiology and Molecular Genetics: Samuni Amram


 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Assayag M, Goldstein S, Samuni A, Berkman N. 3-Carbamoyl-proxyl nitroxide radicals attenuate bleomycin-induced pulmonary fibrosis in mice. Free Radic Biol Med 2021;171:135-142.

(2) Samuni A, Goldstein S. Hydroxylamines inhibit tyrosine oxidation and nitration: The role of their respective nitroxide radicals. Free Radic Biol Med 2020;160:837-844.

(3) Maimon E, Samuni A, Goldstein S. Mechanistic insight into the catalytic inhibition by nitroxides of tyrosine oxidation and nitration. Biochim Biophys Acta Gen Subj 2019;1863(11).

(4) Maimon E, Lerner A, Samuni A, Goldstein S. Direct Observation of Acyl Nitroso Compounds in Aqueous Solution and the Kinetics of Their Reactions with Amines, Thiols, and Hydroxamic Acids. J Phys Chem A 2018;122(35):7006-7013.

(5) Maimon E, Samuni A, Goldstein S. Nitrogen Dioxide Reaction with Nitroxide Radical Derived from Hydroxamic Acids: The Intermediacy of Acyl Nitroso and Nitroxyl (HNO). J Phys Chem A 2018;122(15):3747-3753.

(6) Samuni A, Maimon E, Goldstein S. Nitroxides protect horseradish peroxidase from H2O2-induced inactivation and modulate its catalase-like activity. Biochim Biophys Acta Gen Subj 2017;1861(8):2060-2069.

(7) Samuni A, Maimon E, Goldstein S. Mechanism of HRP-catalyzed nitrite oxidation by H2O2 revisited: Effect of nitroxides on enzyme inactivation and its catalytic activity. Free Radic Biol Med 2017;108:832-839.

(8) Samuni A, Maimon E, Goldstein S. Nitroxides catalytically inhibit nitrite oxidation and heme inactivation induced by H2O2, nitrite and metmyoglobin or methemoglobin. Free Radic Biol Med 2016;101:491-499.

(9) Assayag M, Goldstein S, Samuni A, Berkman N. Cyclic nitroxide radicals attenuate inflammation and Hyper-responsiveness in a mouse model of allergic asthma. Free Radic Biol Med 2015;87:148-156.

(10) Goldstein S, Samuni A. Oxidation mechanism of hydroxamic acids forming HNO and NO. implications for biological activity. Adv Inorg Chem 2015;67:315-333.

(11) Samuni A, Goldstein S. Redox properties of benzoquinone ansamycins in aqueous solutions. Isr J Chem 2014;54(3):316-320.

(12) Samuni A, Goldstein S. Redox properties and thiol reactivity of geldanamycin and its analogues in aqueous solutions. J Phys Chem B 2012;116(22):6404-6410.

(13) Samuni A, Goldstein S. One-electron oxidation of acetohydroxamic acid: The intermediacy of nitroxyl and peroxynitrite. J Phys Chem A 2011;115(14):3022-3028.

(14) Goldstein S, Samuni A. Biologically Relevant Chemistry Of Nitroxides. Stable Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds; 2010. p. 567-578.

(15) Goldstein S, Samuni A, Merenyi G. Kinetics of the reaction between nitroxide and thiyl radicals: Nitroxides as antioxidants in the presence of thiols. J Phys Chem A 2008;112(37):8600-8605.

(16) Ryu S, Ornoy A, Samuni A, Zangen S, Kohen R. Oxidative stress in Cohen diabetic rat model by high-sucrose, low-copper diet: inducing pancreatic damage and diabetes. Metab Clin Exp 2008;57(9):1253-1261.

(17) Ryu S, Kohen R, Samuni A, Ornoy A. Nitroxide radicals protect cultured rat embryos and yolk sacs from diabetic-induced damage. Birth Defects Res Part A Clin Mol Teratol 2007;79(8):604-611.

(18) Aronovitch Y, Godinger D, Israeli A, Krishna MC, Samuni A, Goldstein S. Dual activity of nitroxides as pro- and antioxidants: Catalysis of copper-mediated DNA breakage and H2O2 dismutation. Free Radic Biol Med 2007;42(9):1317-1325.

(19) Goldstein S, Samuni A. Kinetics and mechanism of peroxyl radical reactions with nitroxides. J Phys Chem A 2007;111(6):1066-1072.

(20) Goldstein S, Samuni A, Hideg K, Merenyi G. Structure - Activity relationship of cyclic nitroxides as SOD mimics and scavengers of nitrogen dioxide and carbonate radicals. J Phys Chem A 2006;110(10):3679-3685.

(21) Goldstein S, Samuni A. Intra- and intermolecular oxidation of oxymyoglobin and oxyhemoglobin induced by hydroxyl and carbonate radicals. Free Radic Biol Med 2005;39(4):511-519.

(22) Israeli A, Patt M, Oron M, Samuni A, Kohen R, Goldstein S. Kinetics and mechanism of the comproportionation reaction between oxoammonium cation and hydroxylamine derived from cyclic nitroxides. Free Radic Biol Med 2005;38(3):317-324.

(23) Goldstein S, Merenyi G, Samuni A. Kinetics and mechanism of •NO2 reacting with various oxidation states of myoglobin. J Am Chem Soc 2004;126(48):15694-15701.

(24) Lavi R, Sinyakov M, Samuni A, Shatz S, Friedmann H, Shainberg A, et al. ESR detection of 1O2 reveals enhanced redox activity in illuminated cell cultures. Free Radic Res 2004;38(9):893-902.

(25) Goldstern S, Rosen GM, Russo A, Samuni A. Kinetics of spin trapping superoxide, hydroxyl, and aliphatic radicals by cyclic nitrones. J Phys Chem A 2004;108(32):6679-6685.

(26) Goldstein S, Samuni A, Merenyi G. Reactions of Nitric Oxide, Peroxynitrite, and Carbonate Radicals with Nitroxides and Their Corresponding Oxoammonium Cations. Chem Res Toxicol 2004;17(2):250-257.

(27) Goldstein S, Samuni A, Merenyi G. Erratum: Reactions of nitric oxide, peroxynitrite and carbonate radicals with nitroxides and their corresponding oxoammonium cations (Chemical Research in Toxicology (February 2004) 17, 2 (250-257)). Chem Res Toxicol 2004;17(11):1549.

(28) Goldstein S, Russo A, Samuni A. Reactions of PTIO and Carboxy-PTIO with .NO, .NO 2, and O2.-. J Biol Chem 2003;278(51):50949-50955.

(29) Hoffman A, Goldstein S, Samuni A, Borman JB, Schwalb H. Effect of nitric oxide and nitroxide SOD-mimic on the recovery of isolated rat heart following ischemia and reperfusion. Biochem Pharmacol 2003;66(7):1279-1286.

(30) Lurie Z, Offer T, Russo A, Samuni A, Nitzan D. Do stable nitroxide radicals catalyze or inhibit the degradation of hyaluronic acid? Free Radic Biol Med 2003;35(2):169-178.

(31) Goldstein S, Samuni A, Russo A. Reaction of cyclic nitroxides with nitrogen dioxide: The intermediacy of the oxoammonium cations. J Am Chem Soc 2003;125(27):8364-8370.

(32) Goldstein S, Merenyi G, Russo A, Samuni A. The role of oxoammonium cation in the SOD-mimic activity of cyclic nitroxides. J Am Chem Soc 2003;125(3):789-795.

(33) Xavier S, Yamada K-, Samuni AM, Samuni A, DeGraff W, Krishna MC, et al. Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage. Biochim Biophys Acta Gen Subj 2002;1573(2):109-120.

(34) Samuni A, Goldstein S, Russo A, Mitchell JB, Krishna MC, Neta P. Kinetics and mechanism of hydroxyl radical and OH-adduct radical reactions with nitroxides and with their hydroxylamines. J Am Chem Soc 2002;124(29):8719-8724.

(35) Goldstein S, Samuni A, Aronovitch Y, Godinger D, Russo A, Mitchell JB. Kinetics of paraquat and copper reactions with nitroxides: The effects of nitroxides on the aerobic and anoxic toxicity of paraquat. Chem Res Toxicol 2002;15(5):686-691.

(36) Offer T, Samuni A. Nitroxides inhibit peroxyl radical-mediated DNA scission and enzyme inactivation. Free Radic Biol Med 2002;32(9):872-881.

(37) Zeltcer G, Berenshtein E, Kitrossky N, Chevion M, Samuni A. Time window of nitroxide effect on myocardial ischemic-reperfusion injury potentiated by iron. Free Radic Biol Med 2002;32(9):912-919.

(38) Czapski G, Samuni A, Goldstein S. Superoxide dismutase mimics: Antioxidative and adverse effects. Methods Enzymol 2002;349:234-242.

(39) Offer T, Russo A, Samuni A. The pro-oxidative activity of SOD and nitroxide SOD mimics. FASEB J 2000;14(9):1215-1223.

(40) Bar-On P, Mohsen M, Zhang R, Feigin E, Chevion M, Samuni A. Kinetics of nitroxide reaction with iron(II). J Am Chem Soc 1999;121(35):8070-8073.

(41) Schwartz E, Samuni A, Friedman I, Hempelmann E, Golenser J. The role of superoxide dismutation in malaria parasites. Inflammation 1999;23(4):361-370.

(42) Zamir E, Zhang R, Samuni A, Kogan M, Pe'er J. Nitroxide stable radical suppresses autoimmune uveitis in rats. Free Radic Biol Med 1999;27(1-2):7-15.

(43) Zhang R, Goldstein S, Samuni A. Kinetics of superoxide-induced exchange among nitroxide antioxidants and their oxidized and reduced forms. Free Radic Biol Med 1999;26(9-10):1245-1252.

(44) Samuni A, Karmeli F, Moshen M, Rachmilewitz D. Mechanisms underlying gastric antiulcerative activity of nitroxides in rats. Free Radic Res 1999;30(2):133-140.

(45) Barasch D, Zipori O, Ringel I, Ginsburg I, Samuni A, Katzhendler J. Novel anthraquinone derivatives with redox-active functional groups capable of producing free radicals by metabolism: Are free radicals essential for cytotoxicity? Eur J Med Chem 1999;34(7-8):597-615.

(46) Offer T, Mohsen M, Samuni A. An SOD-mimicry mechanism underlies the role of nitroxides in protecting papain from oxidative inactivation. Free Radic Biol Med 1998;25(7):832-838.

(47) Zhang R, Shohami E, Beit-Yannai E, Bass R, Trembovler V, Samuni A. Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury. Free Radic Biol Med 1998;24(2):332-340.

(48) Zhang R, Pinson A, Samuni A. Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress. Free Radic Biol Med 1998;24(1):66-75.

(49) Udassin R, Haskel Y, Samuni A. Nitroxide radical attenuates ischaemia/reperfusion injury to the rat small intestine. Gut 1998;42(5):623-627.

(50) Zhang R, Shohami E, Beit-Yannai E, Bass R, Trembovler V, Samuni A. Erratum: Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury (Free Radical and Biology Medicine (1998) 24 (332-3410)). Free Radic Biol Med 1998;25(6):753.

(51) Zeltcer G, Berenshtein E, Samuni A, Chevion M. Nitroxide radicals prevent metal-aggravated reperfusion injury in isolated rat heart. Free Radic Res 1997;27(6):627-636.

(52) Krishna MC, Samuni A, Taira J, Goldstein S, Mitchell JB, Russo A. Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism. J Biol Chem 1996;271(42):26018-26025.

(53) Krishna MC, Russo A, Mitchell JB, Goldstein S, Dafni H, Samuni A. Do nitroxide antioxidants act as scavengers of O2/-· or as SOD mimics? J Biol Chem 1996;271(42):26026-26031.

(54) Beit-Yannai E, Zhang R, Trembovler V, Samuni A, Shohami E. Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat. Brain Res 1996;717(1-2):22-28.

(55) Wang G, Godinger D, Aronovitch J, Samuni A. Opposing effects of nitroxide free radicals in Escherichia coli mutants deficient in DNA repair. BIOCHIM BIOPHYS ACTA GENE STRUCT EXPR 1996;1305(1-2):71-78.

(56) Pacelli R, Wink DA, Cook JA, Krishna MC, DeGraff W, Friedman N, et al. Nitric oxide potentiates hydrogen peroxide-induced killing of escherichia coli. J Exp Med 1995;182(5):1469-1479.

(57) Mohsen M, Pinson A, Zhang R, Samuni A. Do nitroxides protect cardiomyocytes from hydrogen peroxide or superoxide? Mol Cell Biochem 1995;145(2):103-110.

(58) Karmeli F, Eliakim R, Okon E, Samuni A, Rachmilewitz D. A stable nitroxide radical effectively decreases mucosal damage in experimental colitis. Gut 1995;37(3):386-393.

(59) Grinberg LN, Samuni A. Nitroxide stable radical prevents primaquine-induced lysis of red blood cells. Biochim Biophys Acta Gen Subj 1994;1201(2):284-288.

(60) Barasch D, Katzhendler J, Krishna MC, Russo A, Samuni A. Novel DMPO-Derived 13C-Labeled Spin Traps Yield Identifiable Stable Nitroxides. J Am Chem Soc 1994;116(16):7319-7324.

(61) Hahn SM, Krishna CM, Samuni A, DeGraff W, Cuscela DO, Johnstone P, et al. Potential use of nitroxides in radiation oncology. Cancer Res 1994;54(7 SUPPL.):2006s-2010s.

(62) Krishna MC, Samuni A. Nitroxides as antioxidants. Methods Enzymol 1994;234(C):580-589.

(63) Rachmilewitz D, Karmeli F, Okon E, Samuni A. A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats. Gut 1994;35(9):1181-1188.

(64) Zhang RL, Hirsch O, Mohsen M, Samuni A. Effects of nitroxide stable radicals on juglone cytotoxicity. Arch Biochem Biophys 1994;312(2):385-391.

(65) Krishna MC, Halevy RF, Zhang R, Gutierrez PL, Samuni A. Modulation of streptonigrin cytotoxicity by nitroxide sod mimics. Free Radic Biol Med 1994;17(5):379-388.

(66) Krishna MC, Samuni A. The effect of oxygen at physiological levels on the detection of free radical intermediates by electron paramagnetic resonance. Free Radic Res 1993;18(4):239-247.

(67) Barenholz Y, Amselem S, Goren D, Cohen R, Gelvan D, Samuni A, et al. Stability of liposomal doxorubicin formulations: Problems and prospects. Med Res Rev 1993;13(4):449-491.

(68) Ginsburg I, Misgav R, Samuni A, Gibbs DF, Varani J, Kohen R. Human neutrophils stimulated by cetyltrimethyl ammonium bromide generate luminol-amplified and non-amplified chemiluminescence but no superoxide production: A paradox. Inflammopharmacology 1992;1(4):337-351.

(69) Krishna MC, Grahame DA, Samuni A, Mitchell JB, Russo A. Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide. Proc Natl Acad Sci U S A 1992;89(12):5537-5541.

(70) Mitchell JB, DeGraff W, Kaufman D, Krishna MC, Samuni A, Finkelstein E, et al. Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, Tempol. Arch Biochem Biophys 1991;289(1):62-70.

(71) Black CDV, Cook OA, Russo A, Samuni A. Superoxide production by stimulated neutrophils: Temperature effect. Free Radic Res 1991;12(1):27-37.

(72) Samuni A, Godinger D, Aronovitch J, Russo A, Mitchell JB. Nitroxides Block DNA Scission and Protect Cells from Oxidative Damage. Biochemistry 1991;30(2):555-561.

(73) Iheanacho EN, Sarel S, Samuni A, Avramovici-Grisaru S, Spira DT. Fe (ii)-chelates based on redox-active pyridoxal-betaines as c-centered radicals causing single- and double-Strand scissions to dna. Free Radic Res 1991;11(6):307-315.

(74) Hahn SM, Krishna CM, Samuni A, Mitchell JB, Russo A. Mn(III)-desferrioxamine superoxide dismutase-mimic: Alternative modes of action. Arch Biochem Biophys 1991;288(1):215-219.

(75) Iheanacho EN, Sarel S, Samuni A, Avramovici-grisaru S, Spira DT. Growth inhibition of plasmodium falciparum involving carbon centered iron-chelate radical (l., x-)-fe(III) based on pyridoxal-betaine. A novel type of antimalarials active against chloroquine-resistant parasites. Free Radic Res 1991;15(1):1-10.

(76) Samuni A, Murali Krishna C, Cook J, Black CDV, Russo A. On radical production by PMA-stimulated neutrophils as monitored by luminol-amplified chemiluminescence. Free Radic Biol Med 1991;10(5):305-313.

(77) Samuni A, Mitchel JB, Degraff W, Krishna CM, Samuni U, Russo A. Nitroxide sod-mimics: Modes of action. Free Radic Res 1991;12(1):187-194.

(78) Samuni A, Winkelsberg D, Pinson A, Hahn SM, Mitchell JB, Russo A. Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage. J Clin Invest 1991;87(5):1526-1530.

(79) Black CDV, Cook JA, Krishna CM, Kaufman DC, Russo A, Samuni A, et al. Kinetics of superoxide production by stimulated neutrophils. Arch Biochem Biophys 1991;286(1):126-131.

(80) Gelvan D, Berg E, Saltman P, Samuni A. Time-dependent modifications of ferric-Adriamycin. Biochem Pharmacol 1990;39(8):1289-1295.

(81) Mitchell JB, Samuni A, Krishna MC, DeGraff WG, Ahn MS, Samuni U, et al. Biologically Active Metal-Independent Superoxide Dismutase Mimics. Biochemistry 1990;29(11):2802-2807.

(82) Iheanacho EN, Samuni A, Avramovici-Grisaru S, Sarel S, Spira DT. Inhibition of Plasmodium falciparum growth by a synthetic iron chelator. Trans R Soc Trop Med Hyg 1990;84(2):213-216.

(83) Samuni A, Min A, Krishna CM, Mitchell JB, Russo A. SOD-like activity of 5-membered ring nitroxide spin labels. ADV EXP MED BIOL 1990;264:85-92.

(84) Samuni A, Krishna CM, Mitchell JB, Collins CR, Russo A. Superoxide reaction with nitroxides. Free Radic Res 1990;9(3-6):241-249.

(85) Sion A, Samuni A, Chevion M. Mechanistic aspects of paraquat toxicity in E. coli. A spin trapping study. Biochem Pharmacol 1989;38(22):3903-3907.

(86) Samuni A, Samuni A, Swartz HM. The cellular-induced decay of DMPO spin adducts of ·OH and ·O2-. Free Radic Biol Med 1989;6(2):179-183.

(87) Samuni A, Samuni A, Swartz HM. Evaluation of dibromonitrosobenzene sulfonate as a spin trap in biological systems. Free Radic Biol Med 1989;7(1):37-43.

(88) Samuni A, Krishna CM, Riesz P, Finkelstein E, Russo A. Superoxide reaction with nitroxide spin-adducts. Free Radic Biol Med 1989;6(2):141-148.

(89) Alegria AE, Samuni A, Mitchell JB, Riesz P, Russo A. Free Radicals Induced by Adriamycin-Sensitive and Adriamycin-Resistant Cells: A Spin-Trapping Study. Biochemistry 1989;28(21):8653-8658.

(90) Samuni A, Krishna CM, Riesz P, Finkelstein E, Russo A. A novel metal-free low molecular weight superoxide dismutase mimic. J Biol Chem 1988;263(34):17921-17924.

(91) Gelvan D, Samuni A. Reappraisal of the Association Between Adriamycin and Iron. Cancer Res 1988;48(20):5645-5649.

(92) Samuni A, Black CDV, Krishna CM, Malech HL, Bernstein EF, Russo A. Hydroxyl radical production by stimulated neutrophils reappraised. J Biol Chem 1988;263(27):13797-13801.

(93) Lerner M, Samuni A, Razin E. Stimulation of murine cultured mast cells under anaerobic conditions: inhibition of arachidonic acid release. Immunol Lett 1987;16(2):121-124.

(94) Aronovitch J, Godinger D, Samuni A, Czapski G. Ascorbic acid oxidation and DNA scission catalyzed by iron and copper chelates. Free Radic Res 1987;2(4-6):241-258.

(95) Samuni A, Carmichael AJ, Russo A, Mitchell JB, Riesz P. On the spin trapping and ESR detection of oxygen-derived radicals generated inside cells. Proc Natl Acad Sci U S A 1986;83(20):7593-7597.

(96) Gelvan D, Samuni A. Cellular targets of adriamycin-induced damage in Escherichia coli. Biochem Pharmacol 1986;35(19):3267-3275.

(97) Samuni A, Chong PL-, Barenholz Y, Thompson TE. Physical and Chemical Modifications of Adriamycin:Lron Complex by Phospholipid Bilayers. Cancer Res 1986;46(2):594-599.


(99) Jacobs GP, Samuni A, Czapski G. The contribution of endogenous and exogenous effects to radiation-induced damage in the bacterial spore. Int J Radiat Biol 1985;47(6):621-627.

(100) Samuni A, Bump EA, Mitchell JB, Brown JM. Enhancement of misonidazole cytotoxicity by iron. Int J Radiat Biol 1985;49(1):77-83.

(101) Samuni A, Chevion M, Czapski G. Roles of copper and O2 in the radiation-induced inactivation of T7 bacteriophage. Radiat Res 1984;99(3):562-572.

(102) CITRI N, KALKSTEIN A, SAMUNI A, ZYK N. Conformational adaptation of RTEM β‐lactamase to cefoxitin. Eur J Biochem 1984;144(2):333-338.

(103) SAMUNI A, ARONOVITCH J, GODINGER D, CHEVION M, CZAPSKI G. On the cytotoxicity of vitamin C and metal ions: A site‐specific Fenton mechanism. Eur J Biochem 1983;137(1-2):119-124.

(104) Samuni A, Chevion M, Czapski G. Unusual copper-induced sensitization of the biological damage due to superoxide radicals. J Biol Chem 1981;256(24):12632-12635.

(105) Finkelstein M, Weidenfeld J, Ne’eman Y, Samuni A, Mizrachi Y, Ben-Uzilio R. Comparative studies of the aromatization of testosterone and epitestosterone by human placental aromatase. Endocrinology 1981;108(3):943-947.

(106) Samuni A, Kalkstein A, Czapski G. Does oxygen enhance the radiation-induced inactivation of penicillinase? Radiat Res 1980;82(1):65-73.

(107) Samuni A, Citri N. How specific is the effect of penicillins on the conformation of penicillinase? An experimental model. Mol Pharmacol 1979;16(1):250-255.

(108) Chevion M, Ilan YA, Samuni A, Navok T, Czapski G. Quaternary structure of methemoglobin. Pulse radiolysis study of the binding of oxygen to the valence hybrid. J Biol Chem 1979;254(14):6370-6374.

(109) Druckmann S, Samuni A, Ottolenghi M. Dynamics of pH-induced spectral changes in bacteriorhodopsin. Biophys J 1979;26(1):143-145.

(110) Samuni A, Meyer AY. Conformation patterns in penicillins and the penicillin-penicillinase interaction. Mol Pharmacol 1978;14(4):704-709.

(111) Samuni A, Chevion M, Halpern YS, Ilan YA, Czapski G. Radiation-induced damage in T4 bacteriophage: The effect of superoxide radicals and molecular oxygen. Radiat Res 1978;75(3):489-496.

(112) Ilan YA, Samuni A, Chevion M, Czapski G. Quaternary states of methemoglobin and its valence-hybrid. A pulse radiolysis study. J Biol Chem 1978;253(1):82-86.

(113) Samuni A, Czapski G. Radiation-induced damage in Escherichia coli B: The effect of superoxide radicals and molecular oxygen. Radiat Res 1978;76(3):624-632.

(114) Samuni A, Meyer AY. Theoretical conformation of penicillins as related to their interaction with penicillinase. Isr J Med Sci 1977;13(9):930.

(115) Citri N, Samuni A, Zyk N. Acquisition of substrate specific parameters during the catalytic reaction of penicillinase. Proc Natl Acad Sci U S A 1976;73(4):1048-1052.

(116) Samuni A, Citri N. Biphasic kinetics induced by modified substrates of penicillinase. Biochem Biophys Res Commun 1975;62(1):7-11.

(117) Samuni A. A direct spectrophotometric assay and determination of Michaelis constants for the β-lactamase reaction. Anal Biochem 1975;63(1):17-26.

(118) Bachrach U, Levin R, Samuni A. Specific effect of T2 internal proteins on the viscosity of T2 DNA. Biochem Biophys Res Commun 1974;60(2):801-806.

(119) Samuni A, Czapski G. Reaction of cerium(IV) perchlorate with hydrogen peroxide. Journal of the Chemical Society, Dalton Transactions 1973(5):487-488.

(120) Behar D, Samuni A. The oxidation of Ti(III) by hydrogen atoms. Chem Phys Lett 1973;22(1):105-106.

(121) Rottem S, Samuni A. Effect of proteins on the motion of spin-labeled fatty acids in mycoplasma membranes. Biochim Biophys Acta Biomembr 1973;298(1):32-38.

(122) Samuni A, Neta P. Hydroxyl radical reaction with phosphate esters and the mechanism of phosphate cleavage. J Phys Chem 1973;77(20):2425-2429.

(123) Samuni A, Neta P. Electron spin resonance study of the reaction of hydroxyl radicals with pyrrole, imidazole, and related compounds. J Phys Chem 1973;77(13):1629-1635.

(124) Meisel D, Czapski G, Samuni A. On the use of the electron spin resonance-flow technique in the study of short-lived radicals. Journal of the Chemical Society, Perkin Transactions 2 1973(12):1702-1708.

(125) Samuni A, Behar D, Fessenden RW. An electron spin resonance study of radicals produced in the photolysis of -keto acids and esters. J Phys Chem 1973;77(6):777-780.

(126) Behar D, Samuni A, Fessenden RW. Reactions of iron(II) and titanium(III) with organic radicals. J Phys Chem 1973;77(17):2055-2059.

(127) Samuni A, Meisel D, Czapski G. The kinetics of the oxidation of chromium(II), titanium(III), and vanadium(IV) by hydrogen peroxide and hydroxyl radicals. Journal of the Chemical Society, Dalton Transactions 1972(12):1273-1277.

(128) Samuni A. The precursors of the metal-complexed hydroperoxyl radical. J Phys Chem 1972;76(16):2207-2213.

(129) Czapski G, Samuni A, Meisel D. The reactions of organic radicals formed by some "fenton-like" reagents. J Phys Chem 1971;75(21):3271-3280.

(130) Samuni A, Czapski G. Oxidation of Ce3+ by HO2 Radical and Ce3+‐HO2 Complex Formation. Isr J Chem 1970;8(3):551-561.

(131) Samuni A, Czapski G. ESR Study of a Complex Formation Between HO2 Radical and Peroxy‐Vanadium (V) Ion. Isr J Chem 1970;8(3):563-573.

(132) Samuni A, Czapski G. Complexes of peroxy radical with transition metal ions. J Phys Chem 1970;74(26):4592-4594.

(133) Czapski G, Samuni A. The Kinetics of Complexed and Free Ho2 Radical in the Reaction of Ce+4 and H2O2. Isr J Chem 1969;7(3):361-373.

(134) Czapski G, Levanon H, Samuni A. ESR Studies of Uncomplexed and Complexed HO2 Radical Formed in the Reaction of H2O2 with Ce4+, Fe2+ and Ti3+ Ions. Isr J Chem 1969;7(3):375-386.

(135) Czapski G, Samuni A, Yelin R. The Disappearance of Ozone in Alkaline Solution. Isr J Chem 1968;6(6):969-971.