The Faculty of Medicine - Biochemistry and Molecular Biology: Shpilka Tomer

1.

Popugailo A, Rotfogel Z, Levy M, Turgeman O, Hillman D, Levy R, et al. The homodimer interfaces of costimulatory receptors B7 and CD28 control their engagement and pro-inflammatory signaling. Journal of Biomedical Science [Internet]. 2023;30(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163653152&doi=10.1186%252fs12929-023-00941-3&partnerID=40&md5=1bbb5c803045bf4c44cf4ca6490b0cba

2.

Uma Naresh N, Kim S, Shpilka T, Yang Q, Du Y, Haynes CM. Mitochondrial genome recovery by ATFS-1 is essential for development after starvation. Cell Reports [Internet]. 2022;41(13). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144413259&doi=10.1016%252fj.celrep.2022.111875&partnerID=40&md5=879c7371b5971cfa44f3b73efd5ec90b

3.

Yang Q, Liu P, Anderson NS, Shpilka T, Du YG, Naresh NU, et al. LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria. Nature Cell Biology [Internet]. 2022;24(2):181–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85124680419&doi=10.1038%252fs41556-021-00840-5&partnerID=40&md5=9d161086c07d0918f3dbe59c5b9c06ed

4.

Shpilka T, Du YG, Yang Q, Melber A, Uma Naresh N, Lavelle J, et al. UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nature Communications [Internet]. 2021;12(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099681825&doi=10.1038%252fs41467-020-20784-y&partnerID=40&md5=cf8e24b6d872916e140fbbfdd4466ead

5.

Milstone ZJ, Saheera S, Bourke LM, Shpilka T, Haynes CM, Trivedi CM. Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis. Science Advances [Internet]. 2020;6(15). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083170709&doi=10.1126%252fsciadv.aax5150&partnerID=40&md5=6c59fe6b7560a0d2da62b05136a9c895

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Shpilka T, Haynes CM. The mitochondrial UPR: Mechanisms, physiological functions and implications in ageing. Nature Reviews Molecular Cell Biology [Internet]. 2018;19(2):109–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85041138005&doi=10.1038%252fnrm.2017.110&partnerID=40&md5=247bfdbc2f38304f92ba7a7436b61d03

7.

Arad G, Levy R, Nasie I, Hillman D, Rotfogel Z, Barash U, et al. Correction to Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock [PLoS Biol, (2015), 13, 8]. PLoS Biology [Internet]. 2015;13(8). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955560812&doi=10.1371%252fjournal.pbio.1002237&partnerID=40&md5=ee10f205aad0e6fec26a7e368b81fee9

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Shpilka T, Welter E, Borovsky N, Amar N, Mari M, Reggiori F, et al. Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis. EMBO Journal [Internet]. 2015;34(16):2117–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939209368&doi=10.15252%252fembj.201490315&partnerID=40&md5=bc19e6e968c19517ef8a7674c7f2fb38

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Shpilka T, Welter E, Borovsky N, Amar N, Shimron F, Peleg Y, et al. Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2015;112(5):1434–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922311450&doi=10.1073%252fpnas.1409476112&partnerID=40&md5=7e94451e2ddb80e75537e6f0e0bf5ad9

10.

Shpilka T, Elazar Z. Lipid droplets regulate autophagosome biogenesis. Autophagy [Internet]. 2015;11(11):2130–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964265562&doi=10.1080%252f15548627.2015.1093719&partnerID=40&md5=ddb55f4a0f5852d59bdd4b0cb7c5e228

11.

Shpilka T, Elazar Z. Essential Role for the Mammalian ATG8 Isoform LC3C in Xenophagy. Molecular Cell [Internet]. 2012;48(3):325–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84869008557&doi=10.1016%252fj.molcel.2012.10.020&partnerID=40&md5=91c3750d647c77de674888a99890e5a6

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Shpilka T, Mizushima N, Elazar Z. Ubiquitin-like proteins and autophagy at a glance. Journal of Cell Science [Internet]. 2012;125(10):2343–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864809503&doi=10.1242%252fjcs.093757&partnerID=40&md5=bcbc373d5dc12f131c4b1478e0916c3b

13.

Rubinsztein DC, Shpilka T, Elazar Z. Mechanisms of autophagosome biogenesis. Current Biology [Internet]. 2012;22(1):R29–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855645313&doi=10.1016%252fj.cub.2011.11.034&partnerID=40&md5=bf73d0195faffcb8e09a469283a53f88

14.

Arad G, Levy R, Nasie I, Hillman D, Rotfogel Z, Barash U, et al. Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock. PLoS Biology [Internet]. 2011;9(9). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80053319600&doi=10.1371%252fjournal.pbio.1001149&partnerID=40&md5=8af1b8badd473e5c1a53f3fdf40cbe62

15.

Shpilka T, Weidberg H, Pietrokovski S, Elazar Z. Atg8: An autophagy-related ubiquitin-like protein family. Genome Biology [Internet]. 2011;12(7). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960878784&doi=10.1186%252fgb-2011-12-7-226&partnerID=40&md5=5d1636f8af4448bb43bb19a2b6a8bfc6

16.

Weidberg H, Shpilka T, Shvets E, Abada A, Shimron F, Elazar Z. LC3 and GATE-16 N Termini Mediate Membrane Fusion Processes Required for Autophagosome Biogenesis. Developmental Cell [Internet]. 2011;20(4):444–54. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79954544250&doi=10.1016%252fj.devcel.2011.02.006&partnerID=40&md5=cf2e252775f2e978632ca92ed24235f5

17.

Shpilka T, Elazar Z. Shedding Light on Mammalian Microautophagy. Developmental Cell [Internet]. 2011;20(1):1–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78651417707&doi=10.1016%252fj.devcel.2010.12.010&partnerID=40&md5=7afa35a005f4dd834d6d850ed4b344d3

18.

Weidberg H, Shpilka T, Shvets E, Elazar Z. Mammalian Atg8s: One is simply not enough. Autophagy [Internet]. 2010;6(6):808–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955901762&doi=10.4161%252fauto.6.6.12579&partnerID=40&md5=b3b9863082aa646f82944dca5d271963

19.

Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z. LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO Journal [Internet]. 2010;29(11):1792–802. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953122645&doi=10.1038%252femboj.2010.74&partnerID=40&md5=01f94ba6ae0902b0fccab9e356fb365b