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The Faculty of Medicine - Biochemistry and Molecular Biology: Chevion Mottie

Researchers

 Last updated June 2021 - School of Pharmacy

List of Publications

(1) Grievink H, Kuzmina N, Chevion M, Drenger B. Sevoflurane postconditioning is not mediated by ferritin accumulation and cannot be rescued by simvastatin in isolated streptozotocin-induced diabetic rat hearts. PLoS ONE 2019;14(1).

(2) Chevion M, Mager J, Glaser G. Naturally occurring food toxicants: Favismproducing agents. CRC Handbook of Naturally Occurring Food Toxicants; 2018. p. 63-80.

(3) Vinokur V, Weksler-Zangen S, Berenshtein E, Eliashar R, Chevion M. The loss of myocardial benefit following ischemic preconditioning is associated with dysregulation of iron homeostasis in diet-induced diabetes. PLoS ONE 2016;11(7).

(4) Grievink H, Zeltcer G, Drenger B, Berenshtein E, Chevion M. Protection by nitric oxide donors of isolated rat hearts is associated with activation of redox metabolism and ferritin accumulation. PLoS ONE 2016;11(7).

(5) Lederman M, Hagbi-Levi S, Grunin M, Obolensky A, Berenshtein E, Banin E, et al. Degeneration modulates retinal response to transient exogenous oxidative injury. PLoS ONE 2014;9(2).

(6) Bibi H, Vinokur V, Waisman D, Elenberg Y, Landesberg A, Faingersh A, et al. Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma. Redox Biol 2014;2(1):814-819.

(7) Vinokur V, Berenshtein E, Bulvik B, Grinberg L, Eliashar R, Chevion M. The Bitter Fate of the Sweet Heart: Impairment of Iron Homeostasis in Diabetic Heart Leads to Failure in Myocardial Protection by Preconditioning. PLoS ONE 2013;8(5).

(8) Goldich Y, Barkana Y, Zadok D, Avni I, Berenshtein E, Rosner M, et al. Use of amphoteric rinsing solution for treatment of ocular tissues exposed to nitrogen mustard. Acta Ophthalmol 2013;91(1):e35-e40.

(9) Parnas L, Chevion M, Berenshtein E, Faibis S, Moskovitz M. Are there metallic traces in black extrinsic dental stain? Quintessence Int 2013;44(5):427-432.

(10) Kurian GA, Berenshtein E, Kakhlon O, Chevion M. Energy status determines the distinct biochemical and physiological behavior of interfibrillar and sub-sarcolemmal mitochondria. Biochem Biophys Res Commun 2012;428(3):376-382.

(11) Bulvik BE, Berenshtein E, Meyron-Holtz EG, Konijn AM, Chevion M. Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins. PLoS ONE 2012;7(11).

(12) Bulvik BE, Berenshtein E, Konijn AM, Grinberg L, Vinokur V, Eliashar R, et al. Aging is an organ-specific process: Changes in homeostasis of iron and redox proteins in the rat. Age 2012;34(3):693-704.

(13) Kurian GA, Berenshtein E, Saada A, Chevion M. Rat cardiac mitochondrial sub-populations show distinct features of oxidative phosphorylation during ischemia, reperfusion and ischemic preconditioning. Cell Physiol Biochem 2012;30(1):83-94.

(14) Obolensky A, Berenshtein E, Lederman M, Bulvik B, Alper-Pinus R, Yaul R, et al. Zinc-desferrioxamine attenuates retinal degeneration in the rd10 mouse model of retinitis pigmentosa. Free Radic Biol Med 2011;51(8):1482-1491.

(15) Vinokur V, Berenshtein E, Chevion M, Eliashar R. Iron homeostasis and methionine-centred redox cycle in nasal polyposis. Free Radic Res 2011;45(3):366-373.

(16) Galbinur T, Obolensky A, Berenshtein E, Vinokur V, Chowers I, Chevion M, et al. Effect of para-aminobenzoic acid on the course of retinal degeneration in the rd10 mouse. J Ocul Pharmacol Ther 2009;25(6):475-482.

(17) Levy S, Chevion M. Synergistic cytotoxic effect of tetrachlorocatechol and sodium azide in Escherichia coli: Toxicity, metabolism, and mechanistic aspects. Environ Toxicol Chem 2009;28(7):1380-1389.

(18) Bulvik B, Grinberg L, Eliashar R, Berenshtein E, Chevion M(). Iron, ferritin and proteins of the methionine-centered redox cycle in young and old rat hearts. Mech Ageing Dev 2009;130(3):139-144.

(19) Deleon E, Lederman M, Berenstein E, Meir T, Chevion M, Chowers I. Alteration in iron metabolism during retinal degeneration in rd10 mouse. Invest Ophthalmol Vis Sci 2009;50(3):1360-1365.

(20) Vinokur V, Grinberg L, Berenshtein E, Gross M, Moskovitz J, Reznick AZ, et al. Methionine-centered redox cycle in organs of the aero-digestive tract of young and old rats. Biogerontology 2009;10(1):43-52.

(21) Chevion M, Leibowitz S, Aye NN, Novogrodsky O, Singer A, Avizemer O, et al. Heart protection by ischemic preconditioning: A novel pathway initiated by iron and mediated by ferritin. J Mol Cell Cardiol 2008;45(6):839-845.

(22) Banin E, Lozinski A, Brady KM, Berenshtein E, Butterfield PW, Moshe M, et al. The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent. Proc Natl Acad Sci U S A 2008;105(43):16761-16766.

(23) Drenger B, Gilon D, Chevion M, Elami A, Meroz Y, Milgalter E, et al. Myocardial Metabolism Altered by Ischemic Preconditioning and Enflurane in Off-Pump Coronary Artery Surgery. J Cardiothorac Vasc Anesth 2008;22(3):369-376.

(24) Obolensky A, Berenshtein E, Konijn AM, Banin E, Chevion M. Ischemic preconditioning of the rat retina: Protective role of ferritin. Free Radic Biol Med 2008;44(7):1286-1294.

(25) Israeli E, Hershcovici T, Berenshtein E, Zannineli G, Wengrower D, Weiss O, et al. The effect of restraint stress on the normal colon and on intestinal inflammation in a model of experimental colitis. Dig Dis Sci 2008;53(1):88-94.

(26) Vinokur V, Leibowitz G, Grinberg L, Eliashar R, Berenshtein E, Chevion M. Diabetes and the heart: Could the diabetic myocardium be protected by preconditioning? Redox Rep 2007;12(6):246-256.

(27) Schaal S, Beiran I, Bormusov E, Chevion M, Dovrat A. Zinc-desferrioxamine reduces damage to lenses exposed to hyperbaric oxygen and has an ameliorative effect on catalase and Na, K-ATPase activities. Exp Eye Res 2007;84(3):455-463.

(28) Schaal S, Beiran I, Rozner H, Rubinstein I, Chevion M, Miller B, et al. Desferrioxamine and zinc-desferrioxamine reduce lens oxidative damage. Exp Eye Res 2007;84(3):561-568.

(29) Levy S, Shechtman S, Zhu B-, Stadtman ER, Stadler R, Chevion M. Synergism between the toxicity of chlorophenols and iron complexes. Environ Toxicol Chem 2007;26(2):218-224.

(30) Kogan NM, Schlesinger M, Priel E, Rabinowitz R, Berenshtein E, Chevion M, et al. HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor. Mol Cancer Ther 2007;6(1):173-183.

(31) Rivo J, Raphael J, Drenger B, Berenshtein E, Chevion M, Gozal Y. Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion. Anesthesiology 2006;105(1):65-71.

(32) Ta-Shma R, Torres A, Chevion M, Breuer E, Quntar AAA, Enk CD, et al. An autoxidation study of C2 substituted pyrimidine amino reductones. Tetrahedron 2006;62(23):5469-5473.

(33) Morad Y, Banin E, Averbukh E, Berenshtein E, Obolensky A, Chevion M. Treatment of ocular tissues exposed to nitrogen mustard: Beneficial effect of zinc desferrioxamine combined with steroids. Invest Ophthalmol Vis Sci 2005;46(5):1640-1646.

(34) Raphael J, Drenger B, Rivo J, Berenshtein E, Chevion M, Gozal Y. Ischemic preconditioning decreases the reperfusion-related formation of hydroxyl radicals in a rabbit model of regional myocardial ischemia and reperfusion: The role of KATP channels. Free Radic Res 2005;39(7):747-754.

(35) Gozal Y, Raphael J, Rivo J, Berenshtein E, Chevion M, Drenger B. Isoflurane does not mimic ischaemic preconditioning in decreasing hydroxyl radical production in the rabbit. Br J Anaesth 2005;95(4):442-447.

(36) Gozal Y, Chevion M, Elami A, Berenshtein E, Kitrossky N, Drenger B. Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion. Eur J Anaesthesiol 2005;22(1):49-55.

(37) Khaliulin I, Borman JB, Chevion M, Schwalb H. Cardioprotective and antioxidant effects of apomorphine. Free Radic Res 2003;37(7):721-730.

(38) Banin E, Morad Y, Berenshtein E, Obolensky A, Yahalom C, Goldich J, et al. Injury induced by chemical warfare agents: Characterization and treatment of ocular tissues exposed to nitrogen mustard. Invest Ophthalmol Vis Sci 2003;44(7):2966-2972.

(39) Zeltcer G, Berenshtein E, Kitrossky N, Chevion M, Samuni A. Time window of nitroxide effect on myocardial ischemic-reperfusion injury potentiated by iron. Free Radic Biol Med 2002;32(9):912-919.

(40) Berenshtein E, Vaisman B, Goldberg-Langerman C, Kitrossky N, Konijn AM, Chevion M. Roles of ferritin and iron in ischemic preconditioning of the heart. Mol Cell Biochem 2002;234-235:283-292.

(41) Zhu B-, Shechtman S, Chevion M. Synergistic cytotoxicity between pentachlorophenol and copper in a bacterial model. Chemosphere 2001;45(4-5):463-470.

(42) Karck M, Tanaka S, Berenshtein E, Sturm C, Haverich A, Chevion M. The push-and-pull mechanism to scavenge redox-active transition metals: A novel concept in myocardial protection. J Thorac Cardiovasc Surg 2001;121(6):1169-1178.

(43) Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, et al. Redox-active iron mediates amyloid-β toxicity. Free Radic Biol Med 2001;30(4):447-450.

(44) Berlett BS, Levine RL, Chock PB, Chevion M, Stadtman ER. Antioxidant activity of Ferrozine-iron-amino acid complexes. Proc Natl Acad Sci U S A 2001;98(2):451-456.

(45) Samuni Y, DeGraff W, Chevion M, Mitchell JB, Cook JA. Radiation sensitization of mammalian cells by metal chelators. Radiat Res 2001;155(2):304-310.

(46) Zhu B-, Chevion M. Mechanism of the synergistic cytotoxicity between pentachlorophenol and copper-1,10-phenanthroline complex: The formation of a lipophilic ternary complex. Chem -Biol Interact 2000;129(3):249-261.

(47) Chevion M, Berenshtein E, Stadtman ER. Human studies related to protein oxidation: Protein carbonyl content as a marker of damage. Free Radic Res 2000;33(SUPPL.):S99-S108.

(48) Zhu B-, Chevion M. Copper-mediated toxicity of 2,4,5-trichlorophenol: Biphasic effect of the copper(I)-specific chelator neocuproine. Arch Biochem Biophys 2000;380(2):267-273.

(49) Amor Y, Chevion M, Levine A. Anoxia pretreatment protects soybean cells against H2O2-induced cell death: Possible involvement of peroxidases and of alternative oxidase. FEBS Lett 2000;477(3):175-180.

(50) Zhu B-, Kitrossky N, Chevion M. Evidence for production of hydroxyl radicals by pentachlorophenol metabolites and hydrogen peroxide: A metal-independent organic Fenton reaction. Biochem Biophys Res Commun 2000;270(3):942-946.

(51) Chevion S, Roberts MA, Chevion M. The use of cyclic voltammetry for the evaluation of antioxidant capacity. Free Radic Biol Med 2000;28(6):860-870.

(52) Witte I, Zhu B-, Lueken A, Magnani D, Stossberg H, Chevion M. Protection by desferrioxamine and other hydroxamic acids against tetrachlorohydroquinone-induced cyto- and genotoxicity in human fibroblasts. Free Radic Biol Med 2000;28(5):693-700.

(53) Banin E, Berenshtein E, Kitrossky N, Pe'Er J, Chevion M. Gallium-desferrioxamine protects the cat retina against injury after ischemia and reperfusion. Free Radic Biol Med 2000;28(3):315-323.

(54) Chevion S, Chevion M. Antioxidant status and human health. Use of cyclic voltammetry for the evaluation of the antioxidant capacity of plasma and of edible plants. Ann New York Acad Sci 2000;899:308-325.

(55) Bar-On P, Mohsen M, Zhang R, Feigin E, Chevion M, Samuni A. Kinetics of nitroxide reaction with iron(II). J Am Chem Soc 1999;121(35):8070-8073.

(56) Samuni Y, Coffin D, DeLuca AM, DeGraff WG, Venson DJ, Ambudkar I, et al. The use of Zn-desferrioxamine for radioprotection in mice, tissue culture, and isolated DNA. Cancer Res 1999;59(2):405-409.

(57) Chevion S, Chevion M, Chock PB, Beecher GR. Antioxidant capacity of edible plants: Extraction protocol and direct evaluation by cyclic voltammetry. J Med Food 1999;2(1):1-10.

(58) Nagler R, Marmary Y, Golan E, Chevion M. Novel protection strategy against X-ray-induced damage to salivary glands. Radiat Res 1998;149(3):271-276.

(59) Zhu B-, Har-El R, Kitrossky N, Chevion M. Erratum: New modes of action of desferrioxamine: Scavenging of semiquinone radical and stimulation of hydrolysis of tetrachlorohydroquinone (Free Radical Biology and Medicine (1997) 24 (360-369)). Free Radic Biol Med 1998;24(5):880.

(60) Zhu B-, Har-El R, Kitrossky N, Chevion M. New modes of action of desferrioxamine: Scavenging of semiquinone radical and stimulation of hydrolysis of tetrachlorohydroquinone. Free Radic Biol Med 1998;24(2):360-369.

(61) Siganos CS, Frucht-Pery J, Muallem MS, Berenshtein E, Naoumidi I, Ever-Hadani P, et al. Topical use of zinc desferrioxamine for corneal alkali injury in a rabbit model. Cornea 1998;17(2):191-195.

(62) Grinberg LN, Newmark H, Kitrossky N, Rahamim E, Chevion M, Rachmilewitz EA. Protective effects of tea polyphenols against oxidative damage to red blood cells. Biochem Pharmacol 1997;54(9):973-978.

(63) Nagler R, Marmary Y, Fox PC, Baum BJ, Har-El R, Chevion M. Irradiation-induced damage to the salivary glands: The role of redox- active iron and copper. Radiat Res 1997;147(4):468-475.

(64) Glantz L, Ginosar Y, Chevion M, Gozal Y, Elami A, Navot N, et al. Halothane prevents postischemic production of hydroxyl radicals in the canine heart. Anesthesiology 1997;86(2):440-447.

(65) Nagler RM, Kitrossky N, Chevion M. Antioxidant activity of rat parotid saliva. ARCH OTOLARYNGOL HEAD NECK SURG 1997;123(9):989-993.

(66) Zeltcer G, Berenshtein E, Samuni A, Chevion M. Nitroxide radicals prevent metal-aggravated reperfusion injury in isolated rat heart. Free Radic Res 1997;27(6):627-636.

(67) Chevion S, Hofmann M, Ziegler R, Chevion M, Nawroth PP. The antioxidant properties of thioctic acid: Characterization by cyclic voltammetry. Biochem Mol Biol Int 1997;41(2):317-327.

(68) Berenshtein E, Mayer B, Goldberg C, Kitrossky N, Chevion M. Patterns of mobilization of copper and iron following myocardial ischemia: Possible predictive criteria for tissue injury. J Mol Cell Cardiol 1997;29(11):3025-3034.

(69) Bierhaus A, Chevion S, Chevion M, Hofmann M, Quehenberger P, Illmer T, et al. Advanced glycation end product-induced activation of NF-κB is suppressed by α-lipoic acid in cultured endothelial cells. Diabetes 1997;46(9):1481-1490.

(70) Schrammel A, Koesling D, Gorren ACF, Chevion M, Schmidt K, Mayer B. Inhibition of purified soluble guanylyl cyclase by copper ions. Biochem Pharmacol 1996;52(7):1041-1045.

(71) Surbek DV, Holzgreve W, Reubinoff BE, Lewin A, Chevion M. Infertility in β-thalassemia major [8]. AM J OBSTET GYNECOL 1996;175(4 I):1080-1081.

(72) Reubinoff BE, Har-El R, Kitrossky N, Friedler S, Levi R, Lewin A, et al. Increased levels of redox-active iron in follicular fluid: A possible cause of free radical-mediated infertility in β-thalassemia major. AM J OBSTET GYNECOL 1996;174(3):914-918.

(73) Schubert D, Chevion M. The role of iron in beta amyloid toxicity. Biochem Biophys Res Commun 1995;216(2):702-707.

(74) Chevion M, Chuang L, Golenser J. Effects of zinc-desferrioxamine on Plasmodium falciparum in culture. Antimicrob Agents Chemother 1995;39(8):1902-1905.

(75) Grinberg LN, Rachmilewitz EA, Kitrossky N, Chevion M. Hydroxyl radical generation in β-thalassemic red blood cells. Free Radic Biol Med 1995;18(3):611-615.

(76) Zer H, Peleg I, Chevion M. The protective effect of desferrioxamine on paraquat‐treated pea Pisum sativum. Physiol Plant 1994;92(3):437-442.

(77) Chevion M, Jiang Y, Har-El R, Berenshtein E, Uretzky G, Kitrossky N. Copper and iron are mobilized following myocardial ischemia: Possible predictive criteria for tissue injury. Proc Natl Acad Sci U S A 1993;90(3):1102-1106.

(78) Zer H, Chevion M, Goldberg I. Effect of paraquat on dark-grown Phaseolus vulgaris cells. Weed Sci 1993;41(4):528-533.

(79) Har-el R, Marva E, Chevion M, Golenser J. Is hemin responsible for the susceptibility of plasmodia to oxidant stress? Free Radic Res 1993;18(5):279-290.

(80) Malkiel S, Har-el R, Schwalb H, Uretzky G, Borman JB, Chevion M. Interaction between allopurinol and copper: Possible role in myocardial protection. Free Radic Res 1993;18(1):7-15.

(81) Ophir A, Berenshtein E, Kitrossky N, Berman ER, Photiou S, Rothman Z, et al. Hydroxyl Radical Generation in the Cat Retina During Reperfusion Following Ischemia. Exp Eye Res 1993;57(3):351-357.

(82) Ophir A, Chevion M. A possible role of free radicals in the transplantation of retinal pigment epithelial cells. Ophthalmic Surg 1992;23(4):284-287.

(83) Peleg I, Zer H, Chevion M. Paraquat toxicity in Pisum sativum: Effects on soluble and membrane‐bound proteins. Physiol Plant 1992;86(1):131-135.

(84) Zusman I, Chevion M, Kitrosski N. Effects of N'methyl-N'-nitro-N-nitrosoguanidine and deoxycholic acid on the content of free radicals in rat serum. Exp Toxicol Pathol 1992;44(4):187-189.

(85) Karck M, Appelbaum Y, Schwalb H, Haverich A, Chevion M, Uretzky G. TPEN, a transition metal chelator, improves myocardial protection during prolonged ischemia. J Heart Lung Transplant 1992;11(5):979-985.

(86) Marva E, Golenser J, Cohen A, Kitrossky N, Har-El R, Chevion M. The effects of ascorbate-induced free radicals on Plasmodium falciparum. Trop Med Parasitol 1992;43(1):17-23.

(87) Golenser J, Kamyl M, Tsafack A, Marva E, Cohen A, Kitrossky N, et al. Correlation between destruction of malarial parasites by polymorphonuclear leucocytes and oxidative stress. Free Radic Res 1992;17(4):249-262.

(88) Powell SR, Chevion M. The effect of chronic administration of doxorubicin on the rat cardiac and hepatic glutathione redox system. Res Commun Chem Pathol Pharmacol 1991;74(3):273-286.

(89) Chevion M. Protection against free radical-induced and transition metal-mediated damage: The use of "pull" and "push" mechanisms. Free Radic Res 1991;13(1):691-696.

(90) Har-el R, Chevion M. Zinc(II) protects against metal-mediated free radical induced damage: Studies on single and double-Strand DNA breakage. Free Radic Res 1991;13(1):509-515.

(91) Cao GW, Chevion M. Bleomycin-detectable iron in brain tissue. Free Radic Res 1991;11(6):317-320.

(92) Haskel Y, Udassin R, Chevion M. MPP+ toxicity in E. Coli under aerobic and anaerobic conditions. Free Radic Res 1991;13(1):697-702.

(93) Karpel R, Marx G, Chevion M. Free radical-induced fibrinogen coagulation: Modulation of neofibe formation by concentration, pH and temperature. Isr J Med Sci 1991;27(2):61-66.

(94) Marva E, Chevion M, Golenser J. The effect of free radicals induced by paraquat and copper on the in vitro development of plasmodium falciparum. Free Radic Res 1991;12(1):137-146.

(95) Golenser J, Marva E, Chevion M. The survival of Plasmodium Under oxidant stress. Parasitol Today 1991;7(6):142-146.

(96) Haskel Y, Udassin R, Chevion M. Mechanistic aspects of 1-methyl-4-phenyl pyridinium iodide toxicity in Escherichia coli: The role of oxygen and hydrogen peroxide. Isr J Med Sci 1991;27(4):207-212.

(97) Golenser J, Marva E, Har-el R, Chevion M. Induction of oxidant stress by iron available in advanced forms of plasmodium falciparum. Free Radic Res 1991;13(1):639-643.

(98) Zer H, Freedman JH, Peisach J, Chevion M. Inverse correlation between resistance towards copper and towards the redox-cycling compound paraquat: A study in copper-tolerant hepatocytes in tissue culture. Free Radic Biol Med 1991;11(1):9-16.

(99) Udassin R, Arieli I, Haskel Y, Kitrossky N, Chevion M. Direct evidence for the involvement of free radicals in ischemic insult to the intestine. Free Radic Res 1991;13(1):721-724.

(100) Udassin R, Ariel I, Haskel Y, Kitrossky N, Chevion M. Salicylate as an in vivo free radical trap: Studies on ischemic insult to the rat intestine. Free Radic Biol Med 1991;10(1):1-6.

(101) Powell S, Saltman P, Uretzky G, Chevion M. Erratum: The effect of zinc on reperfusion arrhythmias in the isolated perfused heart (Free Radical Biology and Medicine 8: (33-46)). Free Radic Biol Med 1990;8(3):307.

(102) Chevion M, Korbashi P, Katzhandler J, Saltman P. Zinc - a redox-inactive metal provides a novel approach for protection against metal-mediated free radical induced injury: Study of paraquat toxicity in E. coli. ADV EXP MED BIOL 1990;264:217-222.

(103) Powell S, Saltman P, Uretzky G, Chevion M. The effect of zinc on reperfusion arrhythmias in the isolated perfused rat heart. Free Radic Biol Med 1990;8(1):33-46.

(104) Appelbaum YJ, Kuvin J, Borman JB, Uretzky G, Chevion M. The protective role of neocuproine against cardiac damage in isolated perfused rat hearts. Free Radic Biol Med 1990;8(2):133-143.

(105) Sion A, Samuni A, Chevion M. Mechanistic aspects of paraquat toxicity in E. coli. A spin trapping study. Biochem Pharmacol 1989;38(22):3903-3907.

(106) Golenser J, Chevion M. Oxidant stress and malaria: host-parasite interrelationships in normal and abnormal erythrocytes. Semin Hematol 1989;26(4):313-325.

(107) Korbashi P, Katzhendler J, Saltman P, Chevion M. Zinc protects Escherichia coli against copper-mediated paraquat-induced damage. J Biol Chem 1989;264(15):8479-8482.

(108) Marva E, Cohen A, Saltman P, Chevion M, Golenser J. Deleterious synergistic effects of ascorbate and copper on the development of Plasmodium falciparum: An in vitro study in normal and in G6PD-deficient erythrocytes. Int J Parasitol 1989;19(7):779-785.

(109) Cao W, Carney JM, Duchon A, Floyd RA, Chevion M. Oxygen free radical involvement in ischemia and reperfusion injury to brain. Neurosci Lett 1988;88(2):233-238.

(110) Kohen R, Chevion M. Cytoplasmic Membrane Is the Target Organelle for Transition Metal Mediated Damage Induced by Paraquat in Escherichia coli. Biochemistry 1988;27(7):2597-2603.

(111) Chevion M. The role of free radicals and transition metals in biological aberrations: The relevance to ageing of the skin. BIOENG SKIN 1988;4(1):39-52.

(112) Chevion M. A site-specific mechanism for free radical induced biological damage: The essential role of redox-active transition metals. Free Radic Biol Med 1988;5(1):27-37.

(113) Higson FK, Kohen R, Chevion M. Iron enhancement of ascorbate toxicity. Free Radic Res 1988;5(2):107-115.

(114) Korbashi P, Kohen R, Katzhendler J, Chevion M. Iron mediates paraquat toxicity in Escherichia coli. J Biol Chem 1986;261(27):12472-12476.

(115) Kohen R, Szyf M, Chevion M. Quantitation of single- and double-strand DNA breaks in vitro and in vivo. Anal Biochem 1986;154(2):485-491.

(116) Marx G, Chevion M. Site-specific modification of albumin by free radicals. Reaction with copper(II) and ascorbate. Biochem J 1986;236(2):397-400.

(117) Kohen R, Chevion M. Involvement of iron and copper in biological damage that is induced by oxygen free radicals. J Free Radic Biol Med 1985;1(5-6):339-340.

(118) Marx G, Chevion M. Fibrinogen coagulation without thrombin: Reaction with vitamin C and copper(II). Thromb Res 1985;40(1):11-18.

(119) Kohen R, Chevion M. Paraquat toxicity is enhanced by iron and reduced by desferrioxamine in laboratory mice. Biochem Pharmacol 1985;34(10):1841-1843.

(120) Kohen R, Chevion M. Letter to the editor. J Free Radic Biol Med 1985;1(5-6):339.

(121) Kohen R, Chevion M, Czapski G. Transition metals potentiate paraquat toxicity. Free Radic Res 1985;1(2):79-88.

(122) Navok T, Chevion M. Transition metals mediate enzymatic inactivation caused by favism-inducing agents. Biochem Biophys Res Commun 1984;122(1):297-303.

(123) Chevion M, Navok T, Pfafferott C, Meiselman HJ, Hochstein P. The effects of isouramil on erythrocyte mechanics: implications for favism. Microcirc Endothelium Lymphatics 1984;1(3):295-306.

(124) Globerman H, Navok T, Chevion M. Haemolysis in a G6PD‐deficient child induced by eating unripe peaches. Scand J Haematol 1984;33(4):337-341.

(125) Kohen R, Friedman M, Chevion M. Iron-treated hydroxyapatite: Structure and function. Pharm Acta Helv 1984;59(8):228-234.

(126) Samuni A, Chevion M, Czapski G. Roles of copper and O2 in the radiation-induced inactivation of T7 bacteriophage. Radiat Res 1984;99(3):562-572.

(127) Shinar E, Navok T, Chevion M. The analogous mechanisms of enzymatic inactivation induced by ascorbate and superoxide in the presence of copper. J Biol Chem 1983;258(24):14778-14783.

(128) Chevion M, Navok T. A novel method for quantitation of favism-inducing agents in legumes. Anal Biochem 1983;128(1):152-158.

(129) Margalioth EJ, Schenker JG, Chevion M. Copper and Zinc levels in normal and malignant tissues. Cancer 1983;52(5):868-872.

(130) Sharma VS, Isaacson RA, John ME, Waterman MR, Chevion M. Reaction of Nitric Oxide with Heme Proteins: Studies on Metmyoglobin, Opossum Methemoglobin, and Microperoxidase. Biochemistry 1983;22(16):3897-3902.

(131) SAMUNI A, ARONOVITCH J, GODINGER D, CHEVION M, CZAPSKI G. On the cytotoxicity of vitamin C and metal ions: A site‐specific Fenton mechanism. Eur J Biochem 1983;137(1-2):119-124.

(132) Golenser J, Miller J, Spira DT, Navok T, Chevion M. Inhibitory effect of a fava bean component on the in vitro development of Plasmodium falciparum in normal and glucose-6-phosphate dehydrogenase deficient erythrocytes. Blood 1983;61(3):507-510.

(133) CHEVION M, NAVOK T, GLASER G, MAGER J. The Chemistry of Favism‐Inducing Compounds: The Properties of Isouramil and Divicine and Their Reaction with Glutathione. Eur J Biochem 1982;127(2):405-409.

(134) Samuni A, Chevion M, Czapski G. Unusual copper-induced sensitization of the biological damage due to superoxide radicals. J Biol Chem 1981;256(24):12632-12635.

(135) Fujita S, Chevion M, Peisach J. Influence of Sex Hormones on Relative Quantities of Multiple Species of Cytochrome P‐450 in Rat Liver Microsomes: A Possible Answer to the Sexual Differences in Metabolic Activities of Rat Liver Microsomes. Isr J Chem 1981;21(1):87-90.

(136) Chevion M, Ilan YA, Navok T, Czapski G. Quaternary Structure and Spin State of Human Fetal Methemoglobin. Isr J Chem 1981;21(1):61-66.

(137) ILAN YA, ILAN Y, CHEVION M, CZAPSKI G. Chain Inequivalence in Bovine Methemoglobin. Eur J Biochem 1980;103(1):161-167.

(138) Chevion M, Ilan YA, Samuni A, Navok T, Czapski G. Quaternary structure of methemoglobin. Pulse radiolysis study of the binding of oxygen to the valence hybrid. J Biol Chem 1979;254(14):6370-6374.

(139) Chevion M, Peisach J, Blumberg WE. Electron paramagnetic resonance study of nitrosyl haemoglobin M Iwate. Int J Biol Macromol 1979;1(5):208-210.

(140) Garfunkel A, Kantzuker M, Gedalia I, Chevion M. Iron concentration in teeth of patients with and without beta-thalassaemia major. Arch Oral Biol 1979;24(10-11):829-831.

(141) Samuni A, Chevion M, Halpern YS, Ilan YA, Czapski G. Radiation-induced damage in T4 bacteriophage: The effect of superoxide radicals and molecular oxygen. Radiat Res 1978;75(3):489-496.

(142) Ilan YA, Samuni A, Chevion M, Czapski G. Quaternary states of methemoglobin and its valence-hybrid. A pulse radiolysis study. J Biol Chem 1978;253(1):82-86.

(143) Rav-Acha C, Chevion M, Katzhendler J, Sarel S. Dipolar Micelles. 6. Catalytic Effects of Betaine-Like Micelles on the Hydrolysis of Substituted Phenyl Esters. J Org Chem 1978;43(4):591-595.

(144) Chevion M, Stern A, Peisach J, Blumberg WE, Simon S. Analogous Effect of Protons and Inositol Hexaphosphate on the Alteration of Structure of Nitrosyl Fetal Human Hemoglobin. Biochemistry 1978;17(9):1745-1750.

(145) Shiffman R, Rav-Acha C, Chevion M, Katzhendler J, Sarel S. Dipolar Micelles. 5. Micellar Effects on the Hydrolysis of Neutral and Charged Esters. J Org Chem 1977;42(20):3279-3284.

(146) Chevion M, Stegeman JJ, Peisach J, Blumberg WE. Electron paramagnetic resonance studies on hepatic microsomal cytochrome P-450 from a marine teleost fish. Life Sci 1977;20(5):895-899.

(147) Chevion M, Traum MM, Blumberg WE, Peisach J. High resolution EPR studies of the fine structure of heme proteins. Third harmonic detection approach. BBA - Protein Structure 1977;490(2):272-278.

(148) Chevion M, Peisach J, Blumberg WE. Imidazole, the ligand trans to mercaptide in ferric cytochrome P 450. An EPR study of proteins and model compounds. J Biol Chem 1977;252(11):3637-3645.

(149) Shiffman R, Chevion M, Katzhendler J, Rav-Acha C, Sarel S. Catalytic Dipolar Micelles. 3. Substrate and Surfactant Structural Effects in the Hydrolyses of Substituted Phenyl Esters in Presence and in Absence of Dipolar Cationic Micelles: Mechanistic Considerations. J Org Chem 1977;42(5):856-863.

(150) Chevion M, Panos C, Paxton J. Membrane Studies of Streptococcus pyogenes and its L-form growing in hypertonic and physiologically isotonic media. An electron spin resonance spectroscopy approach. Biochim Biophys Acta Biomembr 1976;426(2):288-301.

(151) Chevion M, Salhany JM, Peisach J, Castillo CL, Blumberg WE. Iron‐Nitrosyl Bond Configuration in Nitrosyl‐Hemoproteins: A Comparative EPR Study of Hemoglobin A and Hemoglobin Kansas. Isr J Chem 1976;15(3-4):311-317.

(152) Chevion M, Panos C, Linzer R, Neuhaus FC. Incorporation of D-alanine into the membrane of Streptococcus pyogenes and its stabilized L-form. J Bacteriol 1974;120(3):1026-1032.

(153) Chevion M, Katzhendler J, Sarel S. Catalytic Micelles II: Catalysis in Dipolar Micelles. Isr J Chem 1972;10(5):975-978.