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The Faculty of Medicine - Biochemistry and Molecular Biology: Razin Ehud


 Last updated September 2023 - Biochemistry and Molecular Biology 

List of Publications


Hidmi S, Nechushtan H, Razin E, Tshori S. Role of Nudt2 in Anchorage-Independent Growth and Cell Migration of Human Melanoma. International Journal of Molecular Sciences [Internet]. 2023;24(13). Available from:


Pavlyuchenkova AN, Chelombitko MA, Fedorov AV, Kuznetsova MK, Zinovkin RA, Razin E. The Distinct Effects of the Mitochondria-Targeted STAT3 Inhibitors Mitocur-1 and Mitocur-3 on Mast Cell and Mitochondrial Functions. International Journal of Molecular Sciences [Internet]. 2023;24(2). Available from:


Paruchuru LB, Govindaraj S, Razin E. The Critical Role Played by Mitochondrial MITF Serine 73 Phosphorylation in Immunologically Activated Mast Cells. Cells [Internet]. 2022;11(3). Available from:


Govindaraj S, Paruchuru LB, Razin E. The pLysRS-Ap4A pathway in mast cells regulates the switch from host defense to a pathological state. International Journal of Molecular Sciences [Internet]. 2021;22(11). Available from:


Rishiq A, Islam O, Golomb E, Gilon D, Smith Y, Savchenko I, et al. The role played by transcription factor e3 in modulating cardiac hypertrophy. International Heart Journal [Internet]. 2021;62(6):1358–68. Available from:


Chelombitko MA, Chernyak BV, Fedorov AV, Zinovkin RA, Razin E, Paruchuru LB. The Role Played by Mitochondria in FcεRI-Dependent Mast Cell Activation. Frontiers in Immunology [Internet]. 2020;11. Available from:


Yu J, Liu Z, Liang Y, Luo F, Zhang J, Tian C, et al. Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells. Nature Communications [Internet]. 2019;10(1). Available from:


La Shu S, Paruchuru LB, Tay NQ, Chua YL, Yun Foo AS, Yang CM, et al. Ap4A Regulates Directional Mobility and Antigen Presentation in Dendritic Cells. iScience [Internet]. 2019;16:524–34. Available from:


Boulos S, Park MC, Zeibak M, Foo SY, Jeon YK, Kim YT, et al. Erratum: Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma (Oncotarget (2017) 8 (65186-65198) DOI:10.18632/oncotarget.18053). Oncotarget [Internet]. 2018;9(90):36250. Available from:


Erlich TH, Sharkia I, Landolina N, Assayag M, Goldberger O, Berkman N, et al. Modulation of allergic responses by mitochondrial STAT3 inhibitors. Allergy: European Journal of Allergy and Clinical Immunology [Internet]. 2018;73(11):2160–71. Available from:


Motzik A, Amir E, Erlich T, Wang J, Kim BG, Han JM, et al. Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells. Oncogene [Internet]. 2017;36(33):4732–8. Available from:


Sharkia I, Hadad Erlich T, Landolina N, Assayag M, Motzik A, Rachmin I, et al. Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor. Journal of Allergy and Clinical Immunology [Internet]. 2017;140(1):204-214.e8. Available from:


Boulos S, Park MC, Zeibak M, Foo SY, Jeon YK, Kim YT, et al. Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma. Oncotarget [Internet]. 2017;8(39):65186–98. Available from:


Wang J, Fang P, Chase P, Tshori S, Razin E, Spicer TP, et al. Development of an HTS-Compatible Assay for Discovery of Melanoma-Related Microphthalmia Transcription Factor Disruptors Using AlphaScreen Technology. Journal of Biomolecular Screening [Internet]. 2017;22(1):58–66. Available from:


Boulos S, Razin E, Nechushtan H, Rachmin I. Diadenosine Tetraphosphate (Ap4A) in Health and Disease. RNA Technologies [Internet]. 2016;207–19. Available from:


Rachmin I, Amsalem E, Golomb E, Beeri R, Gilon D, Fang P, et al. FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. International Journal of Cardiology [Internet]. 2015;195:85–94. Available from:


Cohen-Saidon C, Nechushtan H, Kahlon S, Livni N, Nissim A, Razin E. Errata: A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival (Blood (2003) 102, 7 (2506-2512)). Blood [Internet]. 2015;125(15):2451. Available from:


Rachmin I, Tshori S, Smith Y, Oppenheim A, Marchetto S, Kay G, et al. Erbin is a negative modulator of cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2014;111(16):5902–7. Available from:


Tshori S, Razin E, Nechushtan H. Amino-acyl tRNA synthetases generate dinucleotide polyphosphates as second messengers: functional implications. Topics in current chemistry [Internet]. 2014;344:189–206. Available from:


Erlich TH, Yagil Z, Kay G, Peretz A, Migalovich-Sheikhet H, Tshori S, et al. Mitochondrial STAT3 plays a major role in IgE-antigen-mediated mast cell exocytosis. Journal of Allergy and Clinical Immunology [Internet]. 2014;134(2):460-469.e10. Available from:


Motzik A, Nechushtan H, Foo SY, Razin E. Non-canonical roles of lysyl-tRNA synthetase in health and disease. Trends in Molecular Medicine [Internet]. 2013;19(12):726–31. Available from:


Ofir-Birin Y, Fang P, Bennett SP, Zhang HM, Wang J, Rachmin I, et al. Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription. Molecular Cell [Internet]. 2013;49(1):30–42. Available from:


Kim DG, Choi JW, Lee JY, Kim H, Oh YS, Lee JW, et al. Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration. FASEB Journal [Internet]. 2012;26(10):4142–59. Available from:


Yagil Z, Hadad Erlich T, Ofir-Birin Y, Tshori S, Kay G, Yekhtin Z, et al. Transcription factor E3, a major regulator of mast cell-mediated allergic response. Journal of Allergy and Clinical Immunology [Internet]. 2012;129(5):1357-1366.e5. Available from:


Carmi-Levy I, Motzik A, Ofir-Birin Y, Yagil Z, Yang CM, Kemeny DM, et al. Importin beta plays an essential role in the regulation of the LysRS-Ap4A pathway in immunologically activated mast cells. Molecular and Cellular Biology [Internet]. 2011;31(10):2111–21. Available from:


Tshori S, Razin E. Editorial: Mast cell degranulation and calcium entry - The Fyn-calcium store connection. Journal of Leukocyte Biology [Internet]. 2010;88(5):837–8. Available from:


Yagil Z, Nechushtan H, Kay G, Yang CM, Kemeny DM, Razin E. The enigma of the role of Protein inhibitor of Activated STAT3 (PIAS3) in the immune response. Trends in Immunology [Internet]. 2010;31(5):199–204. Available from:


Shapira SC, Vinker S, Razin E, Ash N. Military tract of medicine–the need and the vision. Harefuah [Internet]. 2010;149(2):89–90, 124. Available from:


Nechushtan H, Kim S, Kay G, Razin E. Chapter 1 The Physiological Role of Lysyl tRNA Synthetase in the Immune System. Advances in Immunology [Internet]. 2009;103:1–27. Available from:


Yannay-Cohen N, Carmi-Levy I, Kay G, Yang CM, Han JM, Kemeny DM, et al. LysRS Serves as a Key Signaling Molecule in the Immune Response by Regulating Gene Expression. Molecular Cell [Internet]. 2009;34(5):603–11. Available from:


Yagil Z, Kay G, Nechushtan H, Razin E. A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells. Journal of Immunology [Internet]. 2009;182(4):2168–75. Available from:


Carmi-Levy I, Yannay-Cohen N, Kay G, Razin E, Nechushtan H. Diadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cells. Molecular and Cellular Biology [Internet]. 2008;28(18):5777–84. Available from:


Textor B, Licht AH, Tuckermann JP, Jessberger R, Razin E, Angel P, et al. JunB is required for IgE-mediated degranulation and cytokine release of mast cells. Journal of Immunology [Internet]. 2007;179(10):6873–80. Available from:


Tshori S, Sonnenblick A, Yannay-Cohen N, Kay G, Nechushtan H, Razin E. Microphthalmia transcription factor isoforms in mast cells and the heart. Molecular and Cellular Biology [Internet]. 2007;27(11):3911–9. Available from:


Carmi I, Razin E. The role played by key transcription factors in activated mast cells. Immunological Reviews [Internet]. 2007;217(1):280–91. Available from:


Jung MH, Min JL, Sang GP, Sun HL, Razin E, Choi EC, et al. Hierarchical network between the components of the multi-tRNA synthetase complex: Implications for complex formation. Journal of Biological Chemistry [Internet]. 2006;281(50):38663–7. Available from:


Tshori S, Gilon D, Beeri R, Nechushtan H, Kaluzhny D, Pikarsky E, et al. Transcription factor MITF regulates cardiac growth and hypertrophy. Journal of Clinical Investigation [Internet]. 2006;116(10):2673–81. Available from:


Yannay-Cohen N, Razin E. Translation and transcription: The dual functionality of LysRS in mast cells. Molecules and Cells [Internet]. 2006;22(2):127–32. Available from:


Levy C, Lee YN, Nechushtan H, Schueler-Furman O, Sonnenblick A, Hacohen S, et al. Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3. Blood [Internet]. 2006;107(7):2839–45. Available from:


Cohen-Saidon C, Carmi I, Keren A, Razin E. Antiapoptotic function of Bcl-2 in mast cells is dependent on its association with heat shock protein 90β. Blood [Internet]. 2006;107(4):1413–20. Available from:


Nechushtan H, Razin E. Mast cells: Must they always be different? Blood [Internet]. 2006;107(1):1–2. Available from:


MacGlashan D, Galli SJ, Austen KF, Pecht I, Kawakami T, Brown M, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:89–94. Available from:


Stevens R, Kitamura Y, Koyasu S, Rao A, Galli SJ, Ono SJ, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:11–4. Available from:


Metcalfe DD, Oettgen H, Metzger H, Marshall JS, Rivera J, Galli SJ, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:24–38. Available from:


Pecht I, Razin E, Metcalfe DD, Koyasu S, Rivera J, Walls A, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:195–7. Available from:


Austen KF, Galli SJ, Rivera J, Oettgen H, Brown M, Koffer A, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:124–30. Available from:


Ono SJ, Stevens R, Razin E, Kitamura Y, Austen KF, Rivera J, et al. General discussion I. Novartis Foundation Symposium [Internet]. 2005;271:95–9. Available from:


Rivera J, Stevens R, Metcalfe DD, Razin E, Rao A, Ono SJ, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:68–77. Available from:


Koffer A, Rivera J, Stevens R, Razin E, MacGlashan D, Koyasu S, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:47–53. Available from:


Razin E, Monticelli S, Rao A, Rivera J, Stevens R, Brown M, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:187–90. Available from:


Razin E, Austen KF, Rivera J, Marshall JS, Koyasu S, Metcalfe DD, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:176–8. Available from:


Pecht I, Kawakami T, Rivera J, Stevens R, MacDonald SM, Koyasu S, et al. Discussion. Novartis Foundation Symposium [Internet]. 2005;271:108–14. Available from:


Cohen-Saidon C, Razin E. The involvement of Bcl-2 in mast cell apoptosis. Novartis Foundation Symposium [Internet]. 2005;271:191–5. Available from:


Lee YN, Razin E. Nonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcεRI-activated mast cells. Molecular and Cellular Biology [Internet]. 2005;25(20):8904–12. Available from:


Sonnenblick A, Levy C, Razin E. Immunological trigger of mast cells by monomeric IgE: Effect on microphthalmia transcription factor, STAT3 network of interactions. Journal of Immunology [Internet]. 2005;175(3):1450–5. Available from:


Miller AJ, Levy C, Davis IJ, Razin E, Fisher DE. Sumoylation of MITF and its related family members TFE3 and TFEB. Journal of Biological Chemistry [Internet]. 2005;280(1):146–55. Available from:


Sonnenblick A, Levy C, Razin E. Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes. Molecular and Cellular Biology [Internet]. 2004;24(24):10584–92. Available from:


Lee YN, Tuckerman J, Nechushtan H, Schutz G, Razin E, Angel P. c-Fos as a regulator of degranulation and cytokine production in FcεRI-activated mast cells. Journal of Immunology [Internet]. 2004;173(4):2571–7. Available from:


Lee YN, Nechushtan H, Figov N, Razin E. The Function of Lysyl-tRNA Synthetase and Ap4A as Signaling Regulators of MITF Activity in FcεRI-Activated Mast Cells. Immunity [Internet]. 2004;20(2):145–51. Available from:


Levy C, Sonnenblick A, Razin E. Role Played by Microphthalmia Transcription Factor Phosphorylation and Its Zip Domain in Its Transcriptional Inhibition by PIAS3. Molecular and Cellular Biology [Internet]. 2003;23(24):9073–80. Available from:


Cohen-Saidon C, Nechushtan H, Kahlon S, Livni N, Nissim A, Razin E. A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival. Blood [Internet]. 2003;102(7):2506–12. Available from:


Nechushtan H, Razin E. The function of MITF and associated proteins in mast cells. Molecular Immunology [Internet]. 2002;38(16–18):1177–80. Available from:


Levy C, Nechushtan H, Razin E. A new role for the STAT3 inhibitor, PIAS3: A repressor of microphthalmia transcription factor. Journal of Biological Chemistry [Internet]. 2002;277(3):1962–6. Available from:


Nechushtan H, Razin E. Studies of different aspects of the role of protein kinase C in mast cells. International Archives of Allergy and Immunology [Internet]. 2001;124(1–3):130–2. Available from:


Nechushtan H, Leitges M, Cohen C, Kay G, Razin E. Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cβ. Blood [Internet]. 2000;95(5):1752–7. Available from:


Bauer O, Razin E. Mast cell-nerve interactions. News in Physiological Sciences [Internet]. 2000;15(5):213–8. Available from:


Razin E, Zhang ZC, Nechushtan H, Frenkel S, Lee YN, Arudchandran R, et al. Suppression of microphthalmia transcriptional activity by its association with protein kinase C-interacting protein 1 in mast cells. Journal of Biological Chemistry [Internet]. 1999;274(48):34272–6. Available from:


Frenkel S, Kay G, Nechushtan H, Razin E. Nuclear translocation of upstream stimulating factor 2 (USF2) in activated mast cells: A possible role in their survival. Journal of Immunology [Internet]. 1998;161(6):2881–7. Available from:


Zhang ZC, Nechushtan H, Jacob-Hirsch J, Avni D, Meyuhas O, Razin E. Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells. Oncogene [Internet]. 1998;16(6):763–9. Available from:


Nechushtan H, Razin E. Deciphering the early-response transcription factor networks in mast cells. Immunology Today [Internet]. 1998;19(10):441–4. Available from:


Ligumsky M, Kuperstein V, Nechushtan H, Zhang Z, Razin E. Analysis of cytokine profile in human colonic mucosal FcεRI-positive cells by single cell PCR: Inhibition of IL-3 expression in steroid-treated IBD patients. FEBS Letters [Internet]. 1997;413(3):436–40. Available from:


Nechushtan H, Zhang Z, Razin E. Microphthalmia (mi) in murine mast cells: Regulation of its stimuli- mediated expression on the translational level. Blood [Internet]. 1997;89(8):2999–3008. Available from:


Razin E, Lewin I, Zang ZC, Kupershtein V, Jacob-Hirsch J, Nechushtan H, et al. Translational regulation of mast cell USF-2 (fos-interacting protein) synthesis by cytokines and IgE-Ag: The dependency on PKC-β. FASEB Journal [Internet]. 1996;10(6):A1214. Available from:


Necbushtan H, Soreq H, Kuperstein V, Tshoritf S, Razin E. Murine and human mast cells express acetylcholinesterase. FASEB Journal [Internet]. 1996;10(6):A1307. Available from:


Nechushtan H, Soreq H, Kuperstein V, Tshori S, Razin E. Murine and human mast cell express acetylcholinesterase. FEBS Letters [Internet]. 1996;379(1):1–6. Available from:


Lewin I, Jacob-Hirsch J, Zang ZC, Kupershtein V, Szallasi Z, Rivera J, et al. Aggregation of the FcεRI in mast cells induces the synthesis of Fos-interacting protein and increases its DNA binding activity: The dependence on protein kinase C-β. Journal of Biological Chemistry [Internet]. 1996;271(3):1514–9. Available from:


Nechushtan H, Razin E. Regulation of mast cell growth and proliferation. Critical Reviews in Oncology/Hematology [Internet]. 1996;23(2):131–50. Available from:


Chaikin E, Hakeem I, Razin E. The incapability of lnterleukin-4 to induce AP-1 activity in murine mast cells. International Archives of Allergy and Immunology [Internet]. 1995;107(1–3):57–9. Available from:


Cruz JR, Cano F, Razin E, Acheson DWK, Keusch GT. Fecal excretion of leukotriene C4 during human disease due to shigella dysenteriae. Journal of Pediatric Gastroenterology and Nutrition [Internet]. 1995;20(2):179–83. Available from:


Razin E, Pecht I, Rivera J. Signal transduction in the activation of mast cells and basophils. Immunology Today [Internet]. 1995;16(8):370–3. Available from:


Razin E, Szallasi Z, Kazanietz MG, Blumberg PM, Rivera J. Protein kinases C-β and C-ε link the mast cell high-affinity receptor for IgE to the expression of c-fos and c-jun. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1994;91(16):7722–6. Available from:


Chaikin E, Hakeem I, Razin E. Enhancement of interleukin-3-dependent mast cell proliferation by suppression of c-jun expression. Journal of Biological Chemistry [Internet]. 1994;269(11):8498–503. Available from:


Ophir A, Berenshtein E, Ziltener HJ, Razin E. 5-Fluorouracil and mast cell precursors in mice. Experimental Hematology [Internet]. 1993;21(12):1558–62. Available from:


Baranes D, Lewin I, Razin E. Serum modulates mast cell responses to IgE antigen stimulation. European Journal of Immunology [Internet]. 1993;23(1):291–4. Available from:


Lewin I, Nechushtan H, Ke Q, Razin E. Regulation of AP-1 expression and activity in antigen-stimulated mast cells: The role played by protein kinase C and the possible involvement of Fos interacting protein. Blood [Internet]. 1993;82(12):3745–51. Available from:


Razin E, Leslie KB, Schrader JW. Connective tissue mast cells in contact with fibroblasts express IL-3 mRNA. Analysis of single cells by polymerase chain reaction. Journal of Immunology [Internet]. 1991;146(3):981–7. Available from:


Baranes D, Razin E. Protein kinase C regulates proliferation of mast cells and the expression of the mRNAs of fos and jun proto-oncogenes during activation by IgE-Ag or calcium ionophore A23187. Blood [Internet]. 1991;78(9):2354–64. Available from:


Chaikin E, Ziltener HJ, Razin E. Protein kinase C plays an inhibitory role in interleukin 3- and interleukin 4-mediated mast cell proliferation. Journal of Biological Chemistry [Internet]. 1990;265(36):22109–16. Available from:


Davidson S, Gilead L, Amira M, Ginsburg H, Razin E. Synthesis of chondroitin sulfate D and heparin proteoglycans in murine lymph node-derived mast cells. The dependence on fibroblasts. Journal of Biological Chemistry [Internet]. 1990;265(21):12324–30. Available from:


Bashkin P, Razin E, Eldor A, Vlodavsky I. Degranulating mast cells secrete an endoglycosidase that degrades heparan sulfate in subendothelial extracellular matrix. Blood [Internet]. 1990;75(11):2204–12. Available from:


Gilead L, Bibi O, Razin E. Fibroblasts induce heparin synthesis in chondroitin sulfate E containing human bone marrow-derived mast cells. Blood [Internet]. 1990;76(6):1188–95. Available from:


Razin E. Culture of bone marrow-derived mast cells: A model for studying oxidative metabolism of arachidonic acid and synthesis of other molecules derived from membrane phospholipids. Methods in Enzymology [Internet]. 1990;187(C):514–20. Available from:


Matzner Y, Cohn M, Hyam E, Razin E, Fuks Z, Buchanan MR, et al. Generation of lipid neutrophil chemoattractant by irradiated bovine aortic endothelial cells. Journal of Immunology [Internet]. 1988;140(8):2681–5. Available from:


Gilead L, Rahamim E, Ziv I, Or R, Razin E. Cultured human bone marrow-derived mast cells, their similarities to cultured murine E-mast cells. Immunology [Internet]. 1988;63(4):669–75. Available from:


Eliakim R, Karmeli F, Razin E, Rachmilewitz D. Role of platelet-activating factor in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine and prednisolone. Gastroenterology [Internet]. 1988;95(5):1167–72. Available from:


Gilead L, Livni N, Eliakim R, Ligumsky M, Fich A, Okon E, et al. Human gastric mucosal mast cells are chondroitin sulphate E-containing mast cells. Immunology [Internet]. 1987;62(1):23–8. Available from:


Lerner M, Samuni A, Razin E. Stimulation of murine cultured mast cells under anaerobic conditions: inhibition of arachidonic acid release. Immunology Letters [Internet]. 1987;16(2):121–4. Available from:


Baranes D, Matzner J, Razin E. Thrombin-induced calcium-independent degranulation of human neutrophils. Inflammation [Internet]. 1986;10(4):455–61. Available from:


Razin E, Baranes D. Thrombin-induced lysozyme release from human neutrophils and phosphatidylinositol breakdown in cultured mouse E mast cells. Advances in prostaglandin, thromboxane, and leukotriene research [Internet]. 1986;16:135–40. Available from:


Baranes D, Liu FT, Razin E. Thrombin and IgE antigen induce formation of inositol phosphates by mouse E-mast cells. FEBS Letters [Internet]. 1986;206(1):64–8. Available from:


Shalit M, Shoam H, Seno N, Razin E. New role for heparan sulfate: Regulator of leukotriene generation in mouse E-mast cells. Life Sciences [Internet]. 1986;39(10):903–10. Available from:


Eliakim R, Gilead L, Ligumsky M, Okon E, Rachmilewitz D, Razin E. Histamine and chondroitin sulfate E proteoglycan released by cultured human cell colonic mucosa: Indication for possible presence of E mast cells. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1986;83(2):461–4. Available from:


Baranes D, Liu FT, Marx G, Shalit M, Razin E. Regulation of thrombin-induced mast cell degranulation by zinc and manganese. Immunology Letters [Internet]. 1986;12(2–3):95–9. Available from:


Pervin R, Kanner BI, Marx G, Razin E. Thrombin-induced degranulation of cultured bone marrow-derived mast cells: Effect on calcium uptake. Immunology [Internet]. 1985;56(4):667–72. Available from:


Shoam H, Razin E. BW755C inhibits the 5-lipoxygenase in E-mast cells without affecting degranulation. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism [Internet]. 1985;837(1):1–5. Available from:


Razin E, Baranes D, Marx G. Thrombin-Mast cell interactions. Binding and cell activation. Experimental Cell Research [Internet]. 1985;160(2):380–6. Available from:


Marx G, Barnes D, Razin E. Thrombin selective activation of mast cells. Federation Proceedings [Internet]. 1985;44(4):No. 5340. Available from:


Razin E. Activation of the 5-lipoxygenase pathway in E-mast cells by peanut agglutinin. Journal of Immunology [Internet]. 1985;134(2):1142–5. Available from:


Stevens RL, Bloes WF, Seldin DC, Razin E, Katz HR, Austen KF. Inhibition of proliferation of mouse T cell-dependent bone marrow-derived mast cells by rat serum does not change their unique phenotype. Journal of Immunology [Internet]. 1984;133(5):2674–80. Available from:


Razin E, Marx G. Thrombin-induced degranulation of cultured bone marrow-derived mast cells. Journal of Immunology [Internet]. 1984;133(6):3282–5. Available from:


Razin E, Romeo LC, Krilis S, Liu FT, Lewis RA, Corey EJ, et al. An analysis of the relationship between 5-lipoxygenase product generation and the secretion of preformed mediators from mouse bone marrow-derived mast cells. Journal of Immunology [Internet]. 1984;133(2):938–45. Available from:


Razin E, Stevens RL, Austen KF, Caulfield JP, Hein A, Liu FT, et al. Cloned mouse mast cells derived from immunized lymph node cells and from foetal liver cells exhibit characteristics of bone marrow-derived mast cells containing chondroitin sulphate E proteoglycan. Immunology [Internet]. 1984;52(3):563–75. Available from:


Razin E, Ihle JN, Seldin D, Mencia-Huerta JM, Katz HR, LeBlanc PA, et al. Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan. Journal of Immunology [Internet]. 1984;132(3):1479–86. Available from:


Razin E, Lewis RA, Corey EJ, Austen KF. Separation of 5-lipoxygenase product generation and secretion of preformed mediators from mouse bone marrow-derived mast cells (BMMC). Federation Proceedings [Internet]. 1984;43(6):no. 1452. Available from:


Mencia Huerta JM, Lewis RA, Razin E, Austen KF. Antigen-initiated release of platelet-activating factor (PAF-acether) from mouse bone marrow-derived mast cells sensitized with monoclonal IgE. Journal of Immunology [Internet]. 1983;131(6):2958–64. Available from:


Stevens RL, Razin E, Austen KF, Hein A, Caulfield JP, Seno N, et al. Synthesis of chondroitin sulfate E glycosaminoglycan onto p-nitrophenyl-β-D-xyloside and its localization to the secretory granules of rat serosal mast cells and mouse bone marrow-derived mast cells. Journal of Biological Chemistry [Internet]. 1983;258(9):5977–84. Available from:


Mencia-Huerta JM, Razin E, Ringel EW, Corey EJ, Hoover D, Austen KF, et al. Immunologic and ionophore-induced generation of leukotriene B4 from mouse bone marrow-derived mast cells. Journal of Immunology [Internet]. 1983;130(4):1885–90. Available from:


Razin E, Mencia-Huerta JM, Stevens RL, Lewis RA, Liu FT, Corey EJ, et al. IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, β-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cells. Journal of Experimental Medicine [Internet]. 1983;157(1):189–201. Available from:


Razin E, Stevens RL, Akiyama F, Schmid K, Austen KF. Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate. Journal of Biological Chemistry [Internet]. 1982;257(12):7229–36. Available from:


Razin E, Mencia-Huerta JM, Lewis RA, Corey EJ, Austen KF. Generation of leukotriene C4 from a subclass of mast cells differentiated in vitro from mouse bone marrow. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1982;79(15):4665–7. Available from:


Razin E, Cordon-Cardo A, Minick CR, Good RA. Studies on the exocytosis of cultured mast cells derived from mouse bone marrow. Experimental Hematology [Internet]. 1982;10(6):524–32. Available from:


Razin E, Rifkind AB, Cordon-Cardo C, Good RA. Selective growth of a population of human basophil cells in vitro. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1981;78(9 II):5793–6. Available from:


Razin E, Cordon-Cardo C, Good RA. Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1981;78(4 II):2559–61. Available from: