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School of Pharmacy : Reich Reuven


 Last updated Septmber 2023 - School of Pharmacy

List of Publications


Onallah H, Mannully ST, Davidson B, Reich R. Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D. International Journal of Molecular Sciences [Internet]. 2022;23(21). Available from:


Davidson B, Reich R. Pathophysiology roles and translational opportunities of miRNAs in ovarian cancer [Internet]. MicroRNA in Human Malignancies. 2022. Available from:


Catane LJ, Moshel O, Smith Y, Davidson B, Reich R. Splice‐variant knock‐out of tgfβ receptors perturbates the proteome of ovarian carcinoma cells. International Journal of Molecular Sciences [Internet]. 2021;22(23). Available from:


Filippov-Levy N, Davidson B, Reich R. The Biological Role of the Long Non-coding RNA LINK-A in Ovarian Carcinoma. Anticancer Research [Internet]. 2020;40(12):6677–84. Available from:


Filippov-Levy N, Reich R, Davidson B. The biological and clinical role of the long non-coding rna loc642852 in ovarian carcinoma. International Journal of Molecular Sciences [Internet]. 2020;21(15):1–15. Available from:


Chehover M, Reich R, Davidson B. Expression of Wnt pathway molecules is associated with disease outcome in metastatic high-grade serous carcinoma. Virchows Archiv [Internet]. 2020;477(2):249–58. Available from:


Stern-Tal D, Achache H, Jacobs Catane L, Reich R, Tavor Re’em T. Novel 3D embryo implantation model within macroporous alginate scaffolds. Journal of Biological Engineering [Internet]. 2020;14(1). Available from:


Broner EC, Onallah H, Tavor Re’Em T, Davidson B, Reich R. Role of the Exosome Secretion Machinery in Ovarian Carcinoma: In Vitro and in Vivo Models. Journal of Oncology [Internet]. 2020;2020. Available from:


Sherman-Samis M, Onallah H, Holth A, Reich R, Davidson B. SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma. Gynecologic Oncology [Internet]. 2019;153(3):651–60. Available from:


Onallah H, Davidson B, Reich R. Diverse Effects of Lysophosphatidic Acid Receptors on Ovarian Cancer Signaling Pathways. Journal of Oncology [Internet]. 2019;2019. Available from:


Onallah H, Catane LJ, Tropé CG, Hetland Falkenthal TE, Reich R, Davidson B. Activity and clinical relevance of autotaxin and lysophosphatidic acid pathways in high-grade serous carcinoma. Virchows Archiv [Internet]. 2018;473(4):463–70. Available from:


Filippov-Levy N, Cohen-Schussheim H, Tropé CG, Hetland Falkenthal TE, Smith Y, Davidson B, et al. Expression and clinical role of long non-coding RNA in high-grade serous carcinoma. Gynecologic Oncology [Internet]. 2018;148(3):559–66. Available from:


Gutgold N, Davidson B, Catane LJ, Holth A, Hellesylt E, Tropé CG, et al. TGFβ splicing and canonical pathway activation in high-grade serous carcinoma. Virchows Archiv [Internet]. 2017;470(6):665–78. Available from:


Harel-Dassa K, Yedgar S, Tropé CG, Davidson B, Reich R. Phospholipase D messenger RNA expression and clinical role in high-grade serous carcinoma. Human Pathology [Internet]. 2017;62:115–21. Available from:


Broner EC, Tropé CG, Reich R, Davidson B. TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma. Human Pathology [Internet]. 2017;60:180–7. Available from:


Horwitz V, Davidson B, Stern D, Tropé CG, Re’Em TT, Reich R. Ezrin is associated with disease progression in ovarian carcinoma. PLoS ONE [Internet]. 2016;11(9). Available from:


Nymoen DA, Slipicevic A, Holth A, Emilsen E, Falkenthal TEH, Tropé CG, et al. Mir-29a is a candidate biomarker of better survival in metastatic high-grade serous carcinoma. Human Pathology [Internet]. 2016;54:74–81. Available from:


Ravid Y, Formanski M, Smith Y, Reich R, Davidson B. Uterine leiomyosarcoma and endometrial stromal sarcoma have unique miRNA signatures. Gynecologic Oncology [Internet]. 2016;140(3):512–7. Available from:


Davidson B, Holth A, Hellesylt E, Hadar R, Katz B, Tropé CG, et al. HUR mRNA expression in ovarian high-grade serous carcinoma effusions is associated with poor survival. Human Pathology [Internet]. 2016;48:95–101. Available from:


Reich R, Hoffman A, Suresh RR, Shai O, Frant J, Maresca A, et al. Carbamoylphosphonates inhibit autotaxin and metastasis formation in vivo. Journal of Enzyme Inhibition and Medicinal Chemistry [Internet]. 2015;30(5):767–72. Available from:


Katz B, Tropé CG, Reich R, Davidson B. MicroRNAs in Ovarian Cancer. Human Pathology [Internet]. 2015;46(9):1245–56. Available from:


Veerendhar A, Cohen S, Frant J, Supuran CT, Reich R, Breuer E. Synthesis of Enantiomeric Aminoalkylcarbamoylphosphonates and Their Evaluation as Dual-Action Anticancer MMP and Carbonic Anhydrase Inhibitors. Heteroatom Chemistry [Internet]. 2015;26(4):257–69. Available from:


Maimon A, Mogilevsky M, Shilo A, Golan-Gerstl R, Obiedat A, Ben-Hur V, et al. Mnk2 Alternative Splicing Modulates the p38-MAPK Pathway and Impacts Ras-Induced Transformation. Cell Reports [Internet]. 2014;7(2):501–13. Available from:


Reich R, Supuran CT, Breuer E. Tumor microenvironment as target in cancer therapy. Annual Reports in Medicinal Chemistry [Internet]. 2014;49:269–84. Available from:


Vaksman O, Tropé C, Davidson B, Reich R. Exosome-derived miRNAs and ovarian carcinoma progression. Carcinogenesis [Internet]. 2014;35(9):2113–20. Available from:


Davidson B, Trope CG, Reich R. The role of the tumor stroma in ovarian cancer. Frontiers in Oncology [Internet]. 2014;4 MAY. Available from:


Davidson B, Rosenfeld YBZ, Holth A, Hellesylt E, Tropé CG, Reich R, et al. VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival. Human Pathology [Internet]. 2014;45(7):1520–8. Available from:


Davidson B, Nymoen DA, Elgaaen BV, Staff AC, Tropé CG, Kærn J, et al. BUB1 mRNA is significantly co-expressed with AURKA and AURKB mRNA in advanced-stage ovarian serous carcinoma. Virchows Archiv [Internet]. 2014;464(6):701–7. Available from:


Davidson B, Tropé CG, Reich R. The clinical and diagnostic role of microRNAs in ovarian carcinoma. Gynecologic Oncology [Internet]. 2014;133(3):640–6. Available from:


Vaksman O, Davidson B, Tropé C, Reich R. Calreticulin expression is reduced in high-grade ovarian serous carcinoma effusions compared with primary tumors and solid metastases. Human Pathology [Internet]. 2013;44(12):2677–83. Available from:


Davidson B, Smith Y, Nesland JM, Kærn J, Reich R, Tropè CG. Defining a prognostic marker panel for patients with ovarian serous carcinoma effusion. Human Pathology [Internet]. 2013;44(11):2449–60. Available from:


Stavnes HT, Holth A, Don T, Kærn J, Vaksman O, Reich R, et al. HOXB8 expression in ovarian serous carcinoma effusions is associated with shorter survival. Gynecologic Oncology [Internet]. 2013;129(2):358–63. Available from:


Sebban S, Golan-Gerstl R, Karni R, Vaksman O, Davidson B, Reich R. Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer. Clinical and Experimental Metastasis [Internet]. 2013;30(1):103–17. Available from:


Davidson B, Tropé CG, Reich R. Epithelial-mesenchymal transition in ovarian carcinoma. Frontiers in Oncology [Internet]. 2012;2(APR). Available from:


Vaksman O, Hetland TE, Trope’ CG, Reich R, Davidson B. Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma. Human Pathology [Internet]. 2012;43(11):2062–9. Available from:


Momic T, Cohen G, Reich R, Arlinghaus FT, Eble JA, Marcinkiewicz C, et al. Vixapatin (VP12), a C-type lectin-protein from Vipera xantina palestinae venom: Characterization as a novel anti-angiogenic compound. Toxins [Internet]. 2012;4(10):862–77. Available from:


Reich R, Hoffman A, Veerendhar A, Maresca A, Innocenti A, Supuran CT, et al. Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment(1). Journal of Medicinal Chemistry [Internet]. 2012;55(17):7875–82. Available from:


Konstantinovsky S, Davidson B, Reich R. Ezrin and BCAR1/p130Cas mediate breast cancer growth as 3-D spheroids. Clinical and Experimental Metastasis [Internet]. 2012;29(6):527–40. Available from:


Brenne K, Nymoen DA, Reich R, Davidson B. PRAME (preferentially expressed antigen of melanoma) is a novel marker for differentiating serous carcinoma from malignant mesothelioma. American Journal of Clinical Pathology [Internet]. 2012;137(2):240–7. Available from:


Weiss I, Trope CG, Reich R, Davidson B. Hyaluronan synthase and hyaluronidase expression in serous ovarian carcinoma is related to anatomic site and chemotherapy exposure. International Journal of Molecular Sciences [Internet]. 2012;13(10):12925–38. Available from:


Frant J, Veerendhar A, Chernilovsky T, Nedvetzki S, Vaksman O, Hoffman A, et al. Orally Active, Antimetastatic, Nontoxic Diphenyl Ether-Derived Carbamoylphosphonate Matrix Metalloproteinase Inhibitors. ChemMedChem [Internet]. 2011;6(8):1471–7. Available from:


Yuan Y, Leszczynska M, Konstantinovsky S, Tropé CG, Reich R, Davidson B. Netrin-4 is upregulated in breast carcinoma effusions compared to corresponding solid tumors. Diagnostic Cytopathology [Internet]. 2011;39(8):562–6. Available from:


Vaksman O, Stavnes HT, Kærn J, Trope CG, Davidson B, Reich R. miRNA profiling along tumour progression in ovarian carcinoma. Journal of Cellular and Molecular Medicine [Internet]. 2011;15(7):1593–602. Available from:


Revel A, Achache H, Stevens J, Smith Y, Reich R. MicroRNAs are associated with human embryo implantation defects. Human Reproduction [Internet]. 2011;26(10):2830–40. Available from:


Reich R, Hadar S, Davidson B. Expression and clinical role of protein of regenerating liver (PRL) phosphatases in ovarian carcinoma. International Journal of Molecular Sciences [Internet]. 2011;12(2):1133–45. Available from:


Davidson B, Reich R, Trope CG, Wang TL, Shih IM. New determinates of disease progression and outcome in metastatic ovarian carcinoma. Histology and Histopathology [Internet]. 2010;25(12):1591–609. Available from:


Achache H, Tsafrir A, Prus D, Reich R, Revel A. Defective endometrial prostaglandin synthesis identified in patients with repeated implantation failure undergoing in vitro fertilization. Fertility and Sterility [Internet]. 2010;94(4):1271–8. Available from:


Lubetzky R, Mandel D, Mimouni FB, Herman L, Reich R, Reif S. MMP-2 and MMP-9 and their tissue inhibitor in preterm human milk. Journal of Pediatric Gastroenterology and Nutrition [Internet]. 2010;51(2):210–2. Available from:


Bunkholt Elstrand M, Dong HP, Ødegaard E, Holth A, Elloul S, Reich R, et al. Mammalian target of rapamycin is a biomarker of poor survival in metastatic serous ovarian carcinoma. Human Pathology [Internet]. 2010;41(6):794–804. Available from:


Elloul S, Vaksman O, Stavnes HT, Trope CG, Davidson B, Reich R. Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions. Clinical and Experimental Metastasis [Internet]. 2010;27(3):161–72. Available from:


Veerendhar A, Reich R, Breuer E. Phosphorus based inhibitors of matrix metalloproteinases. Comptes Rendus Chimie [Internet]. 2010;13(8–9):1191–202. Available from:


Shatz M, Lustig G, Reich R, Liscovitch M. Caveolin-1 mutants P132L and Y14F are dominant negative regulators of invasion, migration and aggregation in H1299 lung cancer cells. Experimental Cell Research [Internet]. 2010;316(10):1748–62. Available from:


Kohan M, Puxeddu I, Reich R, Levi-Schaffer F, Berkman N. Eotaxin-2/CCL24 and eotaxin-3/CCL26 exert differential profibrogenic effects on human lung fibroblasts. Annals of Allergy, Asthma and Immunology [Internet]. 2010;104(1):66–72. Available from:


Davidson B, Hadar R, Stavnes HT, Trope’ CG, Reich R. Expression of the peroxisome proliferator-activated receptors-α, -β, and -γ in ovarian carcinoma effusions is associated with poor chemoresponse and shorter survival. Human Pathology [Internet]. 2009;40(5):705–13. Available from:


Koler M, Achache H, Tsafrir A, Smith Y, Revel A, Reich R. Disrupted gene pattern in patients with repeated in vitro fertilization (IVF) failure. Human Reproduction [Internet]. 2009;24(10):2541–8. Available from:


Sebban S, Davidson B, Reich R. Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities. Virchows Archiv [Internet]. 2009;454(1):71–9. Available from:


Rayhman O, Klipper E, Muller L, Davidson B, Reich R, Meidan R. Small interfering RNA molecules targeting endothelin-converting enzyme-1 inhibit endothelin-1 synthesis and the invasive phenotype of ovarian carcinoma cells. Cancer Research [Internet]. 2008;68(22):9265–73. Available from:


Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M. Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration. Experimental Cell Research [Internet]. 2008;314(15):2762–73. Available from:


Hoffman A, Qadri B, Frant J, Katz Y, Bhusare SR, Breuer E, et al. Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor - Synthesis and pharmacodynamic and pharmacokinetic analysis (Journal of Medicinal Chemistry (2008) 51, (1408)). Journal of Medicinal Chemistry [Internet]. 2008;51(14):4357–8. Available from:


Kleinberg L, Holth A, Trope CG, Reich R, Davidson B. Claudin upregulation in ovarian carcinoma effusions is associated with poor survival. Human Pathology [Internet]. 2008;39(5):747–57. Available from:


Beylis I, Frant J, Mussai N, Reich R, Breuer E. Carbamoylphosphonates part 7. An efficient method for the synthesis of hindered carbamoylphosphonates using 4-nitrophenoxycarbonylphosphonate diesters. Tetrahedron Letters [Internet]. 2008;49(18):2875–7. Available from:


Hoffman A, Qadri B, Frant J, Katz Y, Bhusare SR, Breuer E, et al. Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor-synthesis and pharmacodynamic and pharmacokinetic analysis. Journal of Medicinal Chemistry [Internet]. 2008;51(5):1406–14. Available from:


Gorovetz M, Schwob O, Krimsky M, Yedgar S, Reich R. MMP production in human fibrosarcoma cells and their invasiveness are regulated by group IB secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2. Frontiers in Bioscience [Internet]. 2008;13(5):1917–25. Available from:


Davidson B, Hadar R, Schlossberg A, Sternlicht T, Slipicevic A, Skrede M, et al. Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma. Human Pathology [Internet]. 2008;39(1):87–95. Available from:


Davidson B, Shafat I, Risberg B, Ilan N, Trope’ CG, Vlodavsky I, et al. Heparanase expression correlates with poor survival in metastatic ovarian carcinoma. Gynecologic Oncology [Internet]. 2007;104(2):311–9. Available from:


Davidson B, Tropé CG, Reich R. Cell adhesion and matrixassociated proteins in ovarian carcinoma [Internet]. Prognostic and Predictive Factors in Gynecologic Cancers. 2007. Available from:


Gorovetz M, Baekelandt M, Berner A, Trope’ CG, Davidson B, Reich R. The clinical role of phospholipase A2 isoforms in advanced-stage ovarian carcinoma. Gynecologic Oncology [Internet]. 2006;103(3):831–40. Available from:


Sivertsen S, Hadar R, Elloul S, Vintman L, Bedrossian C, Reich R, et al. Expression of Snail, Slug and Sip1 in malignant mesothelioma effusions is associated with matrix metalloproteinase, but not with cadherin expression. Lung Cancer [Internet]. 2006;54(3):309–17. Available from:


Elloul S, Silins I, Tropé CG, Benshushan A, Davidson B, Reich R. Expression of E-cadherin transcriptional regulators in ovarian carcinoma. Virchows Archiv [Internet]. 2006;449(5):520–8. Available from:


Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MTP, Bassarova A, Kvalheim G, et al. The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma. Gynecologic Oncology [Internet]. 2006;102(3):453–61. Available from:


Cohen-Sela E, Rosenzweig O, Gao J, Epstein H, Gati I, Reich R, et al. Alendronate-loaded nanoparticles deplete monocytes and attenuate restenosis. Journal of Controlled Release [Internet]. 2006;113(1):23–30. Available from:


Rosenzweig T, Ziv-Av A, Xiang C, Lu W, Cazacu S, Taler D, et al. Related to testes-specific, vespid, and pathogenesis protein-1 (RTVP-1) is overexpressed in gliomas and regulates the growth, survival, and invasion of glioma cells. Cancer Research [Internet]. 2006;66(8):4139–48. Available from:


Alpert E, Gruzman A, Lardi-Studler B, Cohen G, Reich R, Sasson S. Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin-and AMPKα-independent manner. Diabetologia [Internet]. 2006;49(3):562–70. Available from:


Ødegaard E, Staff AC, Kærn J, Flørenes VA, Kopolovic J, Tropé CG, et al. The AP-2γ transcription factor is upregulated in advanced-stage ovarian carcinoma. Gynecologic Oncology [Internet]. 2006;100(3):462–8. Available from:


Davidson B, Risberg B, Berner A, Bedrossian CWM, Reich R. The biological differences between ovarian serous carcinoma and diffuse peritoneal malignant mesothelioma. Seminars in Diagnostic Pathology [Internet]. 2006;23(1):35–43. Available from:


Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. Journal of Allergy and Clinical Immunology [Internet]. 2006;117(1):103–10. Available from:


Tessone A, Feinberg MS, Barbash IM, Reich R, Holbova R, Richmann M, et al. Effect of matrix metalloproteinase inhibition by doxycycline on myocardial healing and remodeling after myocardial infarction. Cardiovascular Drugs and Therapy [Internet]. 2005;19(6):383–90. Available from:


Reich R, Vintman L, Nielsen S, Kærn J, Bedrossian C, Berner A, et al. Differential expression of the 67 kilodalton laminin receptor in epithelioid malignant mesothelioma and carcinomas that spread to serosal cavities. Diagnostic Cytopathology [Internet]. 2005;33(5):332–7. Available from:


Konstantinovsky S, Nielsen S, Vyberg M, Kvalheim G, Nesland JM, Reich R, et al. Angiogenic molecule expression is downregulated in effusions from breast cancer patients. Breast Cancer Research and Treatment [Internet]. 2005;94(1):71–80. Available from:


Cohen S, Katz Y, Reich R, Breuer E. Trans-(4-Methylcyclohexylcarbamoyl)phosphonic acid: A representative matrix metalloproteinase (MMP) inhibitor. Acta Crystallographica Section E: Structure Reports Online [Internet]. 2005;61(9):o3008–10. Available from:


Haimov-Kochman R, Ravhon A, Prus D, Greenfield C, Finci-Yeheskel Z, Goldman-Wohl DS, et al. Expression and regulation of Sprouty-2 in the granulosa-lutein cells of the corpus luteum. Molecular Human Reproduction [Internet]. 2005;11(8):537–42. Available from:


Schaner ME, Davidson B, Skrede M, Reich R, Flørenes VA, Risberg B, et al. Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients. Molecular Cancer [Internet]. 2005;4. Available from:


Haimov-Kochman R, Prus D, Zcharia E, Goldman-Wohl DS, Natanson-Yaron S, Greenfield C, et al. Spatiotemporal expression of heparanase during human and rodent ovarian folliculogenesis. Biology of Reproduction [Internet]. 2005;73(1):20–8. Available from:


Davidson B, Vintman L, Nielsen S, Reich R, Berner A. Site-related expression of metastasis-associated and signaling molecules in malignant mesothelioma - A new model for the study of tumor biology and disease progression. Lung Cancer [Internet]. 2005;49(SUPPL. 1):S89–93. Available from:


Givant-Horwitz V, Davidson B, Reich R. Laminin-induced signaling in tumor cells. Cancer Letters [Internet]. 2005;223(1):1–10. Available from:


Vintman L, Nielsen S, Berner A, Reich R, Davidson B. Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells. Cancer [Internet]. 2005;103(11):2427–33. Available from:


Reif S, Somech R, Brazovski E, Reich R, Belson A, Konikoff FM, et al. Matrix metalloproteinases 2 and 9 are markers of inflammation but not of the degree of fibrosis in chronic hepatitis C. Digestion [Internet]. 2005;71(2):124–30. Available from:


Reich R, Katz Y, Hadar R, Breuer E. Carbamoylphosphonate matrix metalloproteinase inhibitors 3: In vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis. Clinical Cancer Research [Internet]. 2005;11(10):3925–9. Available from:


Elloul S, Elstrand MB, Nesland JM, Tropé CG, Kvalheim G, Goldberg I, et al. Snail, slug, and smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer [Internet]. 2005;103(8):1631–43. Available from:


Breuer E, Frant J, Reich R. Recent non-hydroxamate matrix metalloproteinase inhibitors. Expert Opinion on Therapeutic Patents [Internet]. 2005;15(3):253–69. Available from:


Nedvetzki S, Gonen E, Assayag N, Reich R, Williams RO, Thurmond RL, et al. RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: A different interpretation of redundancy. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2004;101(52):18081–6. Available from:


Davidson B, Konstantinovsky S, Nielsen S, Dong HP, Berner A, Vyberg M, et al. Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: A novel model for tumor progression. Clinical Cancer Research [Internet]. 2004;10(21):7335–46. Available from:


Davidson B, Goldberg I, Tell L, Vigdorchik S, Baekelandt M, Berner A, et al. The clinical role of the PEA3 transcription factor in ovarian and breast carcinoma in effusions. Clinical and Experimental Metastasis [Internet]. 2004;21(3):191–9. Available from:


Breuer E, Katz Y, Hadar R, Reich R. Carbamoylphosphonate MMP inhibitors. Part 4: The influence of chirality and geometrical isomerism on the potency and selectivity of inhibition. Tetrahedron Asymmetry [Internet]. 2004;15(15):2415–20. Available from:


Reif S, Aeed H, Shilo Y, Reich R, Kloog Y, Kweon YO, et al. Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid. Journal of Hepatology [Internet]. 2004;41(2):235–41. Available from:


Offen D, Gilgun-Sherki Y, Barhum Y, Benhar M, Grinberg L, Reich R, et al. A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis. Journal of Neurochemistry [Internet]. 2004;89(5):1241–51. Available from:


Breuer E, Salomon CJ, Katz Y, Chen W, Lu S, Röschenthaler GV, et al. Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids. Journal of Medicinal Chemistry [Internet]. 2004;47(11):2826–32. Available from:


Givant-Horwitz V, Davidson B, Reich R. Laminin-induced signaling in tumor cells: The role of the Mr 67,000 laminin receptor. Cancer Research [Internet]. 2004;64(10):3572–9. Available from:


Givant-Horwitz V, Davidson B, Goderstad JM, Nesland JM, Tropé CG, Reich R. The PAC-1 dual specificity phosphatase predicts poor outcome in serous ovarian carcinoma. Gynecologic Oncology [Internet]. 2004;93(2):517–23. Available from:


Davidson B, Reich R, Lazarovici P, Flørenes VA, Risberg B, Nielsen S, et al. Expression of the nerve growth factor receptors TrkA and p75 in malignant mesothelioma. Lung Cancer [Internet]. 2004;44(2):159–65. Available from:


Ali HA, Berkovitz R, Reich R, Srebnik M. Matrix metallo-proteinase (MMP-2) organoboronate inhibitors. Archiv der Pharmazie [Internet]. 2004;337(4):183–7. Available from:


Farkas E, Katz Y, Bhusare S, Reich R, Röschenthaler GV, Königsmann M, et al. Carbamoylphosphonate-based matrix metalloproteinase inhibitor metal complexes: Solution studies and stability constants. Towards a zinc-selective binding group. Journal of Biological Inorganic Chemistry [Internet]. 2004;9(3):307–15. Available from:


Reichenstein M, Reich R, Lehoux JG, Hanukoglu I. ACTH induces TIMP-1 expression and inhibits collagenase in adrenal cortex cells. Molecular and Cellular Endocrinology [Internet]. 2004;215(1–2):109–14. Available from:


Al-Quntar AAA, Baum O, Reich R, Srebnik M. Recently synthesized class of vinylphosphonates as potent matrix metalloproteinase (MMP-2) inhibitors. Archiv der Pharmazie [Internet]. 2004;337(2):76–80. Available from:


Flørenes VA, Mælandsmo GM, Holm R, Reich R, Lazarovici P, Davidson B. Expression of activated TrkA protein in melanocytic tumors: Relationship to cell profileration and clinical outcome. American Journal of Clinical Pathology [Internet]. 2004;122(3):412–20. Available from:


Davidson B, Vintman L, Zcharia E, Bedrossian C, Berner A, Ielsen S, et al. Heparanase and basic fibroblast growth factor are co-expressed in malignant mesothelioma. Clinical and Experimental Metastasis [Internet]. 2004;21(5):469–76. Available from:


Davidson B, Reich R, Lazarovici P, Flørenes VA, Nielsen S, Nesland JM. Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma. Breast Cancer Research and Treatment [Internet]. 2004;83(2):119–28. Available from:


Givant-Horwitz V, Davidson B, Van De Putte G, Dong HP, Goldberg I, Amir S, et al. Expression of the 67 kDa laminin receptor and the α6 integrin subunit in serous ovarian carcinoma. Clinical and Experimental Metastasis [Internet]. 2003;20(7):599–609. Available from:


Davidson B, Givant-Horwitz V, Lazarovici P, Risberg B, Nesland JM, Trope CG, et al. Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): Co-expression in metastatic serous ovarian carcinoma. Clinical and Experimental Metastasis [Internet]. 2003;20(7):621–31. Available from:


Givant-Horwitz V, Davidson B, Lazarovici P, Schaefer E, Nesland JM, Tropé CG, et al. Mitogen-activated protein kinases (MAPK) as predictors of clinical outcome in serous ovarian carcinoma in effusions. Gynecologic Oncology [Internet]. 2003;91(1):160–72. Available from:


Davidson B, Goldberg I, Reich R, Tell L, Dong HP, Trope’ CG, et al. αv- and β1-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients. Gynecologic Oncology [Internet]. 2003;90(2):248–57. Available from:


Davidson B, Reich R, Lazarovici P, Nesland JM, Skrede M, Risberg B, et al. Expression and activation of the nerve growth factor receptor TrkA in serous ovarian carcinoma. Clinical Cancer Research [Internet]. 2003;9(6):2248–59. Available from:


Davidson B, Goldberg I, Berner A, Kristensen GB, Reich R. EMMPRIN (extracellular matrix metalloproteinase inducer) is a novel marker of poor outcome in serous ovarian carcinoma. Clinical and Experimental Metastasis [Internet]. 2003;20(2):161–9. Available from:


Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Ben-Baruch G, Reich R. PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma. Clinical Cancer Research [Internet]. 2003;9(4):1412–9. Available from:


Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Risberg B, Ben-Baruch G, et al. Coordinated expression of integrin subunits, matrix metalloproteinases (MMP), angiogenic genes and Ets transcription factors in advanced-stage ovarian carcinoma: A possible activation pathway? Cancer and Metastasis Reviews [Internet]. 2003;22(1):103–15. Available from:


Davidson B, Risberg B, Reich R, Berner A. Effusion cytology in ovarian cancer: New molecular methods as aids to diagnosis and prognosis. Clinics in Laboratory Medicine [Internet]. 2003;23(3):729–54. Available from:


Davidson B, Goldberg I, Givant-Horwitz V, Nesland JM, Berner A, Bryne M, et al. Caveolin-1 expression in ovarian carcinoma is MDR1 independent. American Journal of Clinical Pathology [Internet]. 2002;117(2):225–34. Available from:


Danenberg HD, Fishbein I, Gao J, Mönkkönen J, Reich R, Gati I, et al. Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits. Circulation [Internet]. 2002;106(5):599–605. Available from:


Garbuzenko E, Nagler A, Pickholtz D, Gillery P, Reich R, Maquart FX, et al. Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: A direct role for mast cells in skin fibrosis. Clinical and Experimental Allergy [Internet]. 2002;32(2):237–46. Available from:


Pergament I, Reich R, Srebnik M. Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors. Bioorganic and Medicinal Chemistry Letters [Internet]. 2002;12(8):1215–8. Available from:


Davidson B, Reich R, Kopolovic J, Berner A, Nesland JM, Kristensen GB, et al. Interleukin-8 and vascular endothelial growth factor mRNA and protein levels are down-regulated in ovarian carcinoma cells in serous effusions. Clinical and Experimental Metastasis [Internet]. 2002;19(2):135–44. Available from:


Wormser U, Brodsky B, Reich R. Topical treatment with povidone iodine reduces nitrogen mustard-induced skin collagenolytic activity. Archives of Toxicology [Internet]. 2002;76(2):119–21. Available from:


Alpert E, Gruzman A, Totary H, Kaiser N, Reich R, Sasson S. A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: Role of glucose and 12-hydroxyeicosatetraenoic acid. Biochemical Journal [Internet]. 2002;362(2):413–22. Available from:


Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Ben-Baruch G, Nesland JM, et al. The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma. Molecular and Cellular Endocrinology [Internet]. 2002;187(1–2):39–45. Available from:


Davidson B, Reich R, Risberg B, Nesland JM. The biological role and regulation of matrix metalloproteinases (MMP) in cancer. Arkhiv patologii [Internet]. 2002;64(3):47–53. Available from:


Fiucci G, Ravid D, Reich R, Liscovitch M. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene [Internet]. 2002;21(15):2365–75. Available from:


Margolin L, Fishbein I, Banai S, Golomb G, Reich R, Perez LS, et al. Metalloproteinase inhibitor attenuates neointima formation and constrictive remodeling after angioplasty in rats: Augmentative effect of αvβ3 receptor blockade. Atherosclerosis [Internet]. 2002;163(2):269–77. Available from:


Davidson B, Risberg B, Goldberg I, Nesland JM, Berner A, Tropé CG, et al. Ets-1 mRNA expression in effusions of serous ovarian carcinoma patients is a marker of poor outcome. American Journal of Surgical Pathology [Internet]. 2001;25(12):1493–500. Available from:


Davidson B, Reich R, Berner A, Givant-Horwitz V, Goldberg I, Risberg B, et al. Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels. European Journal of Cancer [Internet]. 2001;37(16):2040–9. Available from:


Micera A, Vigneti E, Pickholtz D, Reich R, Pappo O, Bonini S, et al. Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2001;98(11):6162–7. Available from:


Even-Ram SC, Maoz M, Pokroy E, Reich R, Katz BZ, Gutwein P, et al. Tumor Cell Invasion Is Promoted by Activation of Protease Activated Receptor-1 in Cooperation with the αvβ5 Integrin. Journal of Biological Chemistry [Internet]. 2001;276(14):10952–62. Available from:


Davidson B, Goldberg I, Berner A, Nesland JM, Givant-Horwitz V, Bryne M, et al. Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions. American Journal of Clinical Pathology [Internet]. 2001;115(4):517–24. Available from:


Goldberg I, Kopolovic J, Gotlieb WH, Ben-Baruch G, Davidson B, Berner A, et al. αv integrin expression is a novel marker of poor prognosis in advanced-stage ovarian carcinoma. Clinical Cancer Research [Internet]. 2001;7(12):4073–9. Available from:


Davidson B, Nesland JM, Berner A, Risberg B, Goscinski M, Tropé CG, et al. Expression levels of the nerve growth factor receptors TrkA and p75 in effusions and solid tumors of serous ovarian carcinoma patients. Clinical Cancer Research [Internet]. 2001;7(11):3457–64. Available from:


Davidson B, Nesland JM, Goldberg I, Kopolovic J, Gotlieb WH, Bryne M, et al. Caveolin-1 expression in advanced-stage ovarian carcinoma - A clinicopathologic study. Gynecologic Oncology [Internet]. 2001;81(2):166–71. Available from:


Davidson B, Berner A, Nesland JM, Davidson B, Berner A, Nesland JM, et al. Ets-1 messenger RNA expression is a novel marker of poor survival in ovarian carcinoma. Clinical Cancer Research [Internet]. 2001;7(3):551–7. Available from:


Sasson S, Davarashvili A, Reich R. Role of lipoxygenase in the regulation of glucose transport in aortic vascular cells. Advances in Experimental Medicine and Biology [Internet]. 2000;469:377–83. Available from:


Davidson B, Goldberg I, Kopolovic J, Gotlieb WH, Givant-Horwitz V, Nesland JM, et al. Expression of angiogenesis-related genes in ovarian carcinoma - A clinicopathologic study. Clinical and Experimental Metastasis [Internet]. 2000;18(6):501–8. Available from:


Elkin M, Miao HQ, Nagler A, Aingorn E, Reich R, Hemo I, et al. Halofuginone: A potent inhibitor of critical steps in angiogenesis progression. FASEB Journal [Internet]. 2000;14(15):2477–85. Available from:


Davidson B, Goldberg I, Gotlieb WH, Kopolovic J, Ben-Baruch G, Nesland JM, et al. High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma. Clinical and Experimental Metastasis [Internet]. 1999;17(10):799–808. Available from:


Levi-Schaffer F, Garbuzenko E, Rubin A, Reich R, Pickholz D, Gillery P, et al. Human eosinophils regulate human lung- and skin-derived fibroblast properties in vitro: A role for transforming growth factor β (TGF-β). Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1999;96(17):9660–5. Available from:


Elkin M, Reich R, Nagler A, Aingorn E, Pines M, De-Groot N, et al. Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone. Clinical Cancer Research [Internet]. 1999;5(8):1982–8. Available from:


Davidson B, Goldberg I, Kopolovic J, Lerner-Geva L, Gotlieb WH, Ben-Baruch G, et al. MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma - A clinicopathologic study using immunohistochemistry and mRNA in situ hybridization. Gynecologic Oncology [Internet]. 1999;73(3):372–82. Available from:


Tsafriri A, Reich R. Molecular aspects of mammalian ovulation. Experimental and Clinical Endocrinology and Diabetes [Internet]. 1999;107(1):1–11. Available from:


Davidson B, Goldberg I, Kopolovic J, Lerner-Geva L, Gotlieb WH, Weis B, et al. Expression of matrix metalloproteinase-9 in squamous cell carcinoma of the uterine cervix - Clinicopathologic study using immunohistochemistry and mRNA in situ hybridization. Gynecologic Oncology [Internet]. 1999;72(3):380–6. Available from:


Migdal M, Huppertz B, Tessler S, Comforti A, Shibuya M, Reich R, et al. Neuropilin-1 is a placenta growth factor-2 receptor. Journal of Biological Chemistry [Internet]. 1998;273(35):22272–8. Available from:


Even-Ram S, Uziely B, Cohen P, Grisaru-Granovsky S, Maoz M, Ginzburg Y, et al. Thrombin receptor overexpression in malignant and physiological invasion processes. Nature Medicine [Internet]. 1998;4(8):909–14. Available from:


Abramovitch R, Neeman M, Reich R, Stein I, Keshet E, Abraham J, et al. Intercellular communication between vascular smooth muscle and endothelial cells mediated by heparin-binding epidermal growth factor-like growth factor and vascular endothelial growth factor. FEBS Letters [Internet]. 1998;425(3):441–7. Available from:


Dinney CPN, Bielenberg DR, Perrotte P, Reich R, Eve BY, Bucana CD, et al. Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-α administration. Cancer Research [Internet]. 1998;58(4):808–14. Available from:


Davidson B, Goldberg I, Liokumovich P, Kopolovic J, Gotlieb WH, Lerner-Geva L, et al. Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix. International Journal of Gynecological Pathology [Internet]. 1998;17(4):295–301. Available from:


Luca M, Huang S, Gershenwald JE, Singh RK, Reich R, Bar-Eli M. Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. American Journal of Pathology [Internet]. 1997;151(4):1105–13. Available from:


Xie S, Luca M, Huang S, Gutman M, Reich R, Johnson JP, et al. Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis. Cancer Research [Internet]. 1997;57(11):2295–303. Available from:


Sasson S, Kredy-Farahan L, Kaiser N, Reich R. Bovine vascular cells and extracellular matrix interactions: Dual effect of hyperglycemia. Experimental and Clinical Endocrinology and Diabetes [Internet]. 1997;105(SUPPL. 3):54–6. Available from:


Singh RK, Reich R, Radinsky R, Berry KK, Dave BJ, Fidler IJ. Expression of basic fibroblast growth factor is necessary but insufficient for production of metastasis. International Journal of Oncology [Internet]. 1997;10(1):23–31. Available from:


Tsafrin A, Reich R. Tissue remodeling in ovulation: Molecular regulation. Gynecological Endocrinology [Internet]. 1996;10(SUPPL. 4):61–3. Available from:


Reich R, Martin GR. Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells. Prostaglandins [Internet]. 1996;51(1):1–17. Available from:


Williger BT, Reich R, Neeman M, Bercovici T, Liscovitch M. Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells. Journal of Biological Chemistry [Internet]. 1995;270(50):29656–9. Available from:


Singh RK, Gutman M, Reich R, Bar-Eli M. Ultraviolet B Irradiation Promotes Tumorigenic and Metastatic Properties in Primary Cutaneous Melanoma via Induction of Interleukin 8. Cancer Research [Internet]. 1995;55(16):3669–74. Available from:


Reich R, Blumenthal M, Liscovitch M. Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells. Clinical & Experimental Metastasis [Internet]. 1995;13(2):134–40. Available from:


Iwamoto Y, Reich R, Nemeth G, Yamada Y, Martin GR. Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts. Clinical & Experimental Metastasis [Internet]. 1993;11(6):492–501. Available from:


Yagel S, Geva TE, Solomon H, Shimonovitz S, Reich R, Finci-Yeheskel Z, et al. High levels of human chorionic gonadotropin retard first trimester trophoblast invasion in vitro by decreasing urokinase plasminogen activator and collagenase activities. Journal of Clinical Endocrinology and Metabolism [Internet]. 1993;77(6):1506–11. Available from:


Hirsch B, Leonhardt S, Jarry H, Reich R, Tsafriri A, Wuttke W. In vivo measurement of rat ovarian collagenolytic activities. Endocrinology [Internet]. 1993;133(6):2761–5. Available from:


Young CS, Reich R, Spiess S, Pitzel L, Wuttke W, Tsafriri A. Localization of interstitial collagenase gene expression in gilt preovulatory follicles. Endocrine [Internet]. 1993;1(6):481–6. Available from:


Chun SY, Popliker M, Reich R, Tsafriri A. Localization of preovulatory expression of plasminogen activator inhibitor type-1 and tissue inhibitor of metalloproteinase type-1 mRNAs in the rat ovary. Biology of Reproduction [Internet]. 1992;47(2):245–53. Available from:


Brodt P, Reich R, Moroz LA, Chambers AF. Differences in the repertoires of basement membrane degrading enzymes in two carcinoma sublines with distinct patterns of site-selective metastasis. BBA - Molecular Basis of Disease [Internet]. 1992;1139(1–2):77–83. Available from:


Pluznik DH, Fridman R, Reich R. Correlation in the expression of type IV collagenase and the invasive and chemotactic abilities of mylomonocytic cells during differentiation into macrophages. Experimental Hematology [Internet]. 1992;20(1):57–63. Available from:


Kranzfelder D, Reich R, Abisogun AO, Tsafriri A. Preovulatory changes in the perifollicular capillary network in the rat: Role of eicosanoids. Biology of Reproduction [Internet]. 1992;46(3):379–85. Available from:


Reich R, Daphna-Iken D, Chun SY, Popliker M, Slager R, Adelmann-Grill BC, et al. Preovulatory changes in ovarian expression of collagenases and tissue metalloproteinase inhibitor messenger ribonucleic acid: Role of eicosanoids. Endocrinology [Internet]. 1991;129(4):1869–75. Available from:


Frisch SM, Reich R, Collier IE, Genrich LT, Martin B, Goldberg GI. Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells. Oncogene [Internet]. 1990;5(1):75–83. Available from:


GOLDBERG GI, FRISCH SM, HE C, WILHELM SM, REICH R, COLLIER IE. Secreted Proteases: Regulation of Their Activity and Their Possible Role in Metastasis. Annals of the New York Academy of Sciences [Internet]. 1990;580(1):375–84. Available from:


Kanemoto T, Reich R, Royce L, Greatorex D, Adler SH, Shiraishi N, et al. Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1990;87(6):2279–83. Available from:


Fridman R, Scott AF, Muller D, Reich R, Penno MB. The role of cell adhesion and migration in the in vitro invasiveness of mouse adrenal carcinoma cells. Invasion and Metastasis [Internet]. 1990;10(4):208–24. Available from:


Fridman R, Lacal JC, Reich R, Bonfil DR, Ahn C ‐H. Differential effects of phorbol ester on the in vitro invasiveness of malignant and non‐malignant human fibroblast cells. Journal of Cellular Physiology [Internet]. 1990;142(1):55–60. Available from:


Sank AC, Chi M, Shima T, Reich R, Martin GR. Collagenase and PDGF modulate chronic wound repair. Surgical Forum [Internet]. 1989;40:624–7. Available from:


Bonfil RD, Momiki S, Fridman R, Reich R, Reddel R, Harris CC, et al. Enhancement of the invasive ability of a transformed human bronchial epithelial cell line by 12-o-tetra-decanoyl-phorbol-13-acetate and diacylglycerol. Carcinogenesis [Internet]. 1989;10(12):2335–8. Available from:


Ura H, Bonfil RD, Reich R, Reddel R, Pfeifer A, Harris CC, et al. Expression of Type IV Collagenase and Procollagen Genes and Its Correlation with the Tumorigenic, Invasive, and Metastatic Abilities of Oncogene-transformed Human Bronchial Epithelial Cells. Cancer Research [Internet]. 1989;49(16):4615–21. Available from:


Reich R, Royce L, Martin GR. Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells. Biochemical and Biophysical Research Communications [Internet]. 1989;160(2):559–64. Available from:


Bonfil RD, Reddel RR, Ura H, Reich R, Fridman R, Harris CC, et al. Invasive and metastatic potential of a v-ha-ras-transformed human bronchial epithelial cell line. Journal of the National Cancer Institute [Internet]. 1989;81(8):587–94. Available from:


Axelrod JH, Reich R, Miskin R. Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells. Molecular and Cellular Biology [Internet]. 1989;9(5):2133–41. Available from:


Sank A, Chi M, Shima T, Reich R, Martin GR. Increased calcium levels alter cellular and molecular events in wound healing. Surgery [Internet]. 1989;106(6):1141–8. Available from:


Thompson EW, Reich R, Shima TB, Albini A, Graf J, Martin GR, et al. Differential Regulation of Growth and Invasiveness of MCF-7 Breast Cancer Cells by Antiestrogens. Cancer Research [Internet]. 1988;48(23):6764–8. Available from:


Reich R, Stratford B, Klein K, Martin GR, Mueller RA, Fuller GC. Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells. Ciba Foundation symposium [Internet]. 1988;141:193–210. Available from:


Thompson EW, Reich R, Martin GR, Albini A. Factors regulating basement membrane invasion by tumor cells. Cancer treatment and research [Internet]. 1988;40:239–49. Available from:


Reich R, Thompson EW, Iwamoto Y, Martin GR, Deason JR, Fuller GC, et al. Effects of Inhibitors of Plasminogen Activator, Serine Proteinases, and Collagenase IV on the Invasion of Basement Membranes by Metastatic Cells. Cancer Research [Internet]. 1988;48(12):3307–12. Available from:


Abisogun AO, Daphna-Iken D, Reich R, Kranzfelder D, Tsafriri A. Modulatory role of eicosanoids in vascular changes during the preovulatory period in the rat. Biology of Reproduction [Internet]. 1988;38(4):756–62. Available from:


Tsafriri A, Abisogun AO, Reich R. Steroids and follicular rupture at ovulation. Journal of Steroid Biochemistry [Internet]. 1987;27(1–3):359–63. Available from:


Feldman E, Haberman S, Abisogun AO, Reich R, Levran D, Maschiach S, et al. Arachidonic acid metabolism in human granulosa cells: Evidence for cyclooxygenase and lipoxygenase activity in vitro. Human Reproduction [Internet]. 1986;1(6):353–6. Available from:


Reich R, Miskin R, Tsafriri A. Intrafollicular distribution of plasminogen activators and their hormonal regulation in vitro. Endocrinology [Internet]. 1986;119(4):1588–93. Available from:


Reich R, Kohen F, Slager R, Tsafriri A. Ovarian lipoxygenase activity and its regulation by gonadotropin in the rat. Prostaglandins [Internet]. 1985;30(4):581–90. Available from:


Reich R, Miskin R, Tsafriri A. Follicular plasminogen activator: Involvement in ovulation. Endocrinology [Internet]. 1985;116(2):516–21. Available from:


Reich R, Tsafriri A, Mechanic GL. The involvement of collagenolysis in ovulation in the rat. Endocrinology [Internet]. 1985;116(2):522–7. Available from:


Reich R, Kohen F, Naor Z, Tsafriri A. Possible involvement of lipoxygenase products of arachidonic acid pathway in ovulation. Prostaglandins [Internet]. 1983;26(6):1011–20. Available from:


Laufer N, Reich R, Braw R, Shenker JG, Tsafriri A. Effect of clomiphene citrate on preovulatory rat follicles in culture. Biology of Reproduction [Internet]. 1982;27(2):463–71. Available from:


Reich R, Laufer N, Lewysohn O, Cordova T, Ayalon D, Tsafriri A. In vitro effects of cannabinoids on follicular function in the rat. Biology of Reproduction [Internet]. 1982;27(1):223–31. Available from:


Ben-Jonathan N, Braw RH, Laufer N, Reich R, Bahr JM, Tsafriri A. Norepinephrine in graafian follicles is depleted by follicle-stimulating hormone. Endocrinology [Internet]. 1982;110(2):457–61. Available from: