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School of Pharmacy : Golomb Gershon

Researchers

 Last updated Septmber 2023 - School of Pharmacy

List of Publications

1.

Agbaria M, Jbara-Agbaria D, Grad E, Ben-David-Naim M, Aizik G, Golomb G. Nanoparticles of VAV1 siRNA combined with LL37 peptide for the treatment of pancreatic cancer. Journal of Controlled Release [Internet]. 2023;355:312–26. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147544706&doi=10.1016%252fj.jconrel.2023.01.084&partnerID=40&md5=e2983fbba8078a02a6db3190f9fa3073

2.

Hirsch S, Hinden L, Naim MBD, Baraghithy S, Permyakova A, Azar S, et al. Hepatic targeting of the centrally active cannabinoid 1 receptor (CB1R) blocker rimonabant via PLGA nanoparticles for treating fatty liver disease and diabetes. Journal of Controlled Release [Internet]. 2023;353:254–69. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85143528111&doi=10.1016%252fj.jconrel.2022.11.040&partnerID=40&md5=e2edaefdd17e2f721e5487deb7fc7946

3.

Biswas S, Rust LN, Wettengel JM, Yusova S, Fischer M, Carson JN, et al. Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity. Nature Communications [Internet]. 2022;13(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130895830&doi=10.1038%252fs41467-022-30593-0&partnerID=40&md5=5d7995eed7972f87ed085641d33c7282

4.

Jbara-Agbaria D, Blondzik S, Burger-Kentischer A, Agbaria M, Nordling-David MM, Giterman A, et al. Liposomal siRNA Formulations for the Treatment of Herpes Simplex Virus-1: In Vitro Characterization of Physicochemical Properties and Activity, and In Vivo Biodistribution and Toxicity Studies. Pharmaceutics [Internet]. 2022;14(3). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127097172&doi=10.3390%252fpharmaceutics14030633&partnerID=40&md5=0d89d08cbdef64f01ff509d66acc6775

5.

Shvindelman O, Nordling-David MM, Grad E, Golomb G. Harnessing Monocytes for a Liposomal Rosiglitazone-Mediated Anti-Inflammatory Effect. Precision Nanomedicine [Internet]. 2022;5(4):930–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159659208&doi=10.33218%252f001c.38312&partnerID=40&md5=d659848576cd7d431bc45d1d460755e2

6.

Aizik G, Waiskopf N, Agbaria M, Ben-David-Naim M, Nordling-David MM, Jbara-Agbaria D, et al. Targeting and imaging of monocyte-derived macrophages in rat’s injured artery following local delivery of liposomal quantum dots. Journal of Controlled Release [Internet]. 2020;318:145–57. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076559543&doi=10.1016%252fj.jconrel.2019.12.009&partnerID=40&md5=ef72c87b8c964db6191dfb3ff972eafa

7.

Aizik G, Waiskopf N, Agbaria M, Ben-David-Naim M, Levi-Kalisman Y, Shahar A, et al. Liposomes of Quantum Dots Configured for Passive and Active Delivery to Tumor Tissue. Nano Letters [Internet]. 2019;19(9):5844–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072134106&doi=10.1021%252facs.nanolett.9b01027&partnerID=40&md5=48afce524f29a42454895a0b48f09f0d

8.

Grad E, Gutman D, Golomb M, Efraim R, Oppenheim A, Richter I, et al. Monocyte Modulation by Liposomal Alendronate Improves Cardiac Healing in a Rat Model of Myocardial Infarction. Regenerative Engineering and Translational Medicine [Internet]. 2019;5(3):280–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073012050&doi=10.1007%252fs40883-019-00103-8&partnerID=40&md5=9c8fdd05443b5f68f950b593e38531b9

9.

Ben-David-Naim M, Dagan A, Grad E, Aizik G, Nordling-David MM, Clyne AM, et al. Targeted siRNA nanoparticles for mammary carcinoma therapy. Cancers [Internet]. 2019;11(4). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065305603&doi=10.3390%252fcancers11040442&partnerID=40&md5=e78ea2b3d0c526b738a6e41ee6101096

10.

Chorny M, Levy RJ, Golomb G. Cardiovascular delivery of drugs and biotherapeutics. Drug Delivery and Translational Research [Internet]. 2018;8(4):865–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049243020&doi=10.1007%252fs13346-018-0483-y&partnerID=40&md5=b0b79a202b1b159cbe54ff2ab032b1b6

11.

Aizik G, Grad E, Golomb G. Monocyte-mediated drug delivery systems for the treatment of cardiovascular diseases. Drug Delivery and Translational Research [Internet]. 2018;8(4):868–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049169246&doi=10.1007%252fs13346-017-0431-2&partnerID=40&md5=f43fcc1ba5bd3c3019d6ec945eba4ae7

12.

Grad E, Zolotarevsky K, Danenberg HD, Nordling-David MM, Gutman D, Golomb G. The role of monocyte subpopulations in vascular injury following partial and transient depletion. Drug Delivery and Translational Research [Internet]. 2018;8(4):945–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043480488&doi=10.1007%252fs13346-017-0404-5&partnerID=40&md5=ff1ca1f2a55074302dd237dba2d3824d

13.

Ben David-Naim M, Grad E, Aizik G, Nordling-David MM, Moshel O, Granot Z, et al. Polymeric nanoparticles of siRNA prepared by a double-emulsion solvent-diffusion technique: Physicochemical properties, toxicity, biodistribution and efficacy in a mammary carcinoma mice model. Biomaterials [Internet]. 2017;145:154–67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028427631&doi=10.1016%252fj.biomaterials.2017.08.036&partnerID=40&md5=912aa8cf30ff0530d3157f8246347388

14.

Nordling-David MM, Yaffe R, Guez D, Meirow H, Last D, Grad E, et al. Liposomal temozolomide drug delivery using convection enhanced delivery. Journal of Controlled Release [Internet]. 2017;261:138–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021446059&doi=10.1016%252fj.jconrel.2017.06.028&partnerID=40&md5=1a0de4135ee5b08cffe4b2ec899d57fe

15.

Aizik G, Waiskopf N, Agbaria M, Levi-Kalisman Y, Banin U, Golomb G. Delivery of Liposomal Quantum Dots via Monocytes for Imaging of Inflamed Tissue. ACS Nano [Internet]. 2017;11(3):3038–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85016393733&doi=10.1021%252facsnano.7b00016&partnerID=40&md5=b2292ba5caedfcee0f07fe28fca20bcc

16.

Ron-Doitch S, Sawodny B, Kühbacher A, David MMN, Samanta A, Phopase J, et al. Reduced cytotoxicity and enhanced bioactivity of cationic antimicrobial peptides liposomes in cell cultures and 3D epidermis model against HSV. Journal of Controlled Release [Internet]. 2016;229:163–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962415123&doi=10.1016%252fj.jconrel.2016.03.025&partnerID=40&md5=9f598ff14a8e02564e0e2123a090e48e

17.

Epstein H, Afergan E, Koroukhov N, Eisenberg G, Gutman D, Golomb G. Liposomal bisphosphonates for the treatment of restenosis [Internet]. Vol. 2, Liposome Technology: Third Edition. 2016. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85052168926&partnerID=40&md5=755ed7354233f9e4a27ea58069ab1b3b

18.

Lurier E, Levy R, Barbee K, Golomb G, Spiller KL. Effects of radical oxygen species and antioxidants on macrophage polarization. In: 2015 41st Annual Northeast Biomedical Engineering Conference, NEBEC 2015 [Internet]. 2015. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941101646&doi=10.1109%252fNEBEC.2015.7117113&partnerID=40&md5=10d7037d664cf0322d44d096b0fdb452

19.

Burwitz BJ, Reed JS, Hammond KB, Ohme MA, Planer SL, Legasse AW, et al. Technical advance: Liposomal alendronate depletes monocytes and macrophages in the nonhuman primate model of human disease. Journal of Leukocyte Biology [Internet]. 2014;96(3):491–501. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907358202&doi=10.1189%252fjlb.5TA0713-373R&partnerID=40&md5=3cf8cc5314eb02de4267b997c6259617

20.

Nordling-David MM, Golomb G. Gene delivery by liposomes. Israel Journal of Chemistry [Internet]. 2013;53(9–10):737–47. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84894634150&doi=10.1002%252fijch.201300055&partnerID=40&md5=07043d9d6513b61b87d7fc7981256e6b

21.

Gutman D, Golomb G. Liposomal alendronate for the treatment of restenosis. Journal of Controlled Release [Internet]. 2012;161(2):619–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862688093&doi=10.1016%252fj.jconrel.2011.11.037&partnerID=40&md5=ab73885832d584ce7e813e7d35fe35a9

22.

Reufsteck C, Lifshitz-Shovali R, Zepp M, Bäuerle T, Kübler D, Golomb G, et al. Silencing of skeletal metastasis-associated genes impairs migration of breast cancer cells and reduces osteolytic bone lesions. Clinical and Experimental Metastasis [Internet]. 2012;29(5):441–56. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862335808&doi=10.1007%252fs10585-012-9462-8&partnerID=40&md5=9d6384bb46de92153833e8dca3fa5c77

23.

Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R, et al. In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2011;108(48):19347–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-82755187704&doi=10.1073%252fpnas.1115945108&partnerID=40&md5=d3fcc1726bab70902b314b750c396d52

24.

Gutman D, Epstein-Barash H, Tsuriel M, Golomb G. Alendronate liposomes for antitumor therapy: Activation of γδ T cells and inhibition of tumor growth. Advances in Experimental Medicine and Biology [Internet]. 2011;733:165–79. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934442719&doi=10.1007%252f978-94-7-2555-3_16&partnerID=40&md5=d5618d32459def31ea2ac0a1d47881d0

25.

Afergan E, Najajreh Y, Gutman D, Epstein H, Elmalak O, Golomb G. 31P-NMR and differential scanning calorimetry studies for determining vesicle’s drug physical state and fraction in alendronate liposomes. Journal of Bioanalysis and Biomedicine [Internet]. 2010;2(6):125–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952585735&doi=10.4172%252f1948-593X.1000035&partnerID=40&md5=10a068791d6d68215f975e8c613b274d

26.

Haber E, Afergan E, Epstein H, Gutman D, Koroukhov N, Ben-David M, et al. Route of administration-dependent anti-inflammatory effect of liposomal alendronate. Journal of Controlled Release [Internet]. 2010;148(2):226–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649323529&doi=10.1016%252fj.jconrel.2010.08.030&partnerID=40&md5=9be7fbc64737ca31d38e7e8ea0f312e2

27.

Epstein-Barash H, Gutman D, Markovsky E, Mishan-Eisenberg G, Koroukhov N, Szebeni J, et al. Physicochemical parameters affecting liposomal bisphosphonates bioactivity for restenosis therapy: Internalization, cell inhibition, activation of cytokines and complement, and mechanism of cell death. Journal of Controlled Release [Internet]. 2010;146(2):182–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955416877&doi=10.1016%252fj.jconrel.2010.03.011&partnerID=40&md5=52c22ecc9d1bf5e66c4508c012313372

28.

Afergan E, David MB, Epstein H, Koroukhov N, Gilhar D, Rohekar K, et al. Liposomal simvastatin attenuates neointimal hyperplasia in rats. AAPS Journal [Internet]. 2010;12(2):181–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950685982&doi=10.1208%252fs12248-010-9173-5&partnerID=40&md5=1415639735e2af4725e69cdb52caba9d

29.

Elazar V, Adwan H, Bäuerle T, Rohekar K, Golomb G, Berger MR. Sustained delivery and efficacy of polymeric nanoparticles containing osteopontin and bone sialoprotein antisenses in rats with breast cancer bone metastasis. International Journal of Cancer [Internet]. 2010;126(7):1749–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77449113087&doi=10.1002%252fijc.24890&partnerID=40&md5=a1f3851042833be3cc93844ff42a3c27

30.

Chan JM, Zhang L, Tong R, Ghosh D, Gao W, Liao G, et al. Spatiotemporal controlled delivery of nanoparticles to injured vasculature. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2010;107(5):2213–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-76649118810&doi=10.1073%252fpnas.0914585107&partnerID=40&md5=ee5d5f0cf878744a032c314f14afee47

31.

Cohen-Sela E, Chorny M, Gutman D, Komemi S, Koroukhov N, Golomb G. Characterization of monocytes-targeted nanocarriers biodistribution in leukocytes in ex-vivo and in-vivo models. Nano Biomedicine and Engineering [Internet]. 2010;2(2):91–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649325465&doi=10.5101%252fnbe.v2i2.p91-99&partnerID=40&md5=53882baea70e97c03c50067166c6a687

32.

Elazar V, Adwan H, Rohekar K, Zepp M, Lifshitz-Shovali R, Berger MR, et al. Biodistribution of antisense nanoparticles in mammary carcinoma rat model. Drug Delivery [Internet]. 2010;17(6):408–18. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954273248&doi=10.3109%252f10717541003777225&partnerID=40&md5=6ab01753b2cb33537854f28e198a2d51

33.

Breuer E, Chorghade MS, Fischer J, Golomb G. Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009). Pure and Applied Chemistry [Internet]. 2009;81(5):971–99. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-67649363798&doi=10.1351%252fPAC-REC-04-10-14&partnerID=40&md5=de89df948b1d584271e8be384f15d37d

34.

Cohen-Sela E, Chorny M, Koroukhov N, Danenberg HD, Golomb G. A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. Journal of Controlled Release [Internet]. 2009;133(2):90–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-57349143801&doi=10.1016%252fj.jconrel.2008.09.073&partnerID=40&md5=965461d94cc786db31d84447ab8cbdf6

35.

Afergan E, Epstein H, Koroukhov N, Klein M, Litchi A, Mishani E, et al. Biodistribution and imaging studies of 67Ga-labeled liposomes in rabbits with a vascular injury. Journal of Drug Delivery Science and Technology [Internet]. 2009;19(4):263–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249113493&doi=10.1016%2fS1773-2247%2809%2950050-0&partnerID=40&md5=22d7ad7dc1f9f16f0bcfcb5a2e83f87f

36.

Gutman D, Epstein H, Koroukhov N, Golomb G. Liposomal delivery system of adenosine for modulating inflammation. Journal of Drug Delivery Science and Technology [Internet]. 2009;19(4):257–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249084975&doi=10.1016%2fS1773-2247%2809%2950049-4&partnerID=40&md5=7bd611d69653e8bb6729e1a9eb6ba7a0

37.

Cohen-Sela E, Teitlboim S, Chorny M, Koroukhov N, Danenberc HD, Gao J, et al. Single and double emulsion manufacturing techniques of an amphiphilic drug in PLGA nanoparticles: Formulations of mithramycin and bioactivity. Journal of Pharmaceutical Sciences [Internet]. 2009;98(4):1452–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-67449168069&doi=10.1002%252fjps.21527&partnerID=40&md5=7e1825e4882147bc4673d17a55d80505

38.

Haber E, Danenberg HD, Koroukhov N, Ron-El R, Golomb G, Schachter M. Peritoneal macrophage depletion by liposomal bisphosphonate attenuates endometriosis in the rat model. Human Reproduction [Internet]. 2009;24(2):398–407. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-58449108637&doi=10.1093%252fhumrep%252fden375&partnerID=40&md5=2d7a2b84b68188c511f7dfdd7505285e

39.

Afergan E, Epstein H, Dahan R, Koroukhov N, Rohekar K, Danenberg HD, et al. Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes. Journal of Controlled Release [Internet]. 2008;132(2):84–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-56349113764&doi=10.1016%252fj.jconrel.2008.08.017&partnerID=40&md5=57702b81965a71013f275818dbe24d7d

40.

Epstein H, Gutman D, Cohen-Sela E, Haber E, Elmalak O, Koroukhov N, et al. Preparation of alendronate liposomes for enhanced stability and bioactivity: In vitro and in vivo characterization. AAPS Journal [Internet]. 2008;10(4):505–15. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-65549118918&doi=10.1208%252fs12248-008-9060-5&partnerID=40&md5=d24e5007d9d4b3e80d9535e72541162b

41.

Epstein H, Grad E, Golomb M, Koroukhov N, Edelman ER, Golomb G, et al. Innate immunity has a dual effect on vascular healing: Suppression and aggravation of neointimal formation and remodeling post-endotoxin challenge. Atherosclerosis [Internet]. 2008;199(1):41–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-45449103496&doi=10.1016%252fj.atherosclerosis.2007.10.034&partnerID=40&md5=93792d45294de985c67cafcea0a696bb

42.

Markovsky E, Koroukhov N, Golomb G. Additive-free albumin nanoparticles of alendronate for attenuating inflammation through monocyte inhibition. Nanomedicine [Internet]. 2007;2(4):545–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548406554&doi=10.2217%252f17435889.2.4.545&partnerID=40&md5=9d1f8b0563379ea2ed34a2fb33a4a93b

43.

Cohen-Sela E, Elazar V, Epstein-Barash H, Golomb G. Nano-Carriers of drugs and genes for the treatment of restenosis [Internet]. Nanoparticulate Drug Delivery Systems. 2007. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015888227&partnerID=40&md5=47666313a38b94f7b65b2fa34cf03f22

44.

Epstein H, Berger V, Levi I, Eisenberg G, Koroukhov N, Gao J, et al. Nanosuspensions of alendronate with gallium or gadolinium attenuate neointimal hyperplasia in rats. Journal of Controlled Release [Internet]. 2007;117(3):322–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846796351&doi=10.1016%252fj.jconrel.2006.10.030&partnerID=40&md5=412258e314017519688596066906cf26

45.

Cohen-Sela E, Dangoor D, Epstein H, Gati I, Danenberg HD, Golomb G, et al. Nanospheres of a bisphosphonate attenuate intimal hyperplasia. Journal of Nanoscience and Nanotechnology [Internet]. 2006;6(9–10):3226–34. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33750067376&doi=10.1166%252fjnn.2006.428&partnerID=40&md5=500c656c62b4d17a930d842ee29ff9f7

46.

Chorny M, Mishaly D, Leibowitz A, Domb AJ, Golomb G. Site-specific delivery of dexamethasone from biodegradable implants reduces formation of pericardial adhesions in rabbits. Journal of Biomedical Materials Research - Part A [Internet]. 2006;78(2):276–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745938553&doi=10.1002%252fjbm.a.30755&partnerID=40&md5=b6029fb0b0d8398d560d1b7fe7bf1a41

47.

Cohen-Sela E, Rosenzweig O, Gao J, Epstein H, Gati I, Reich R, et al. Alendronate-loaded nanoparticles deplete monocytes and attenuate restenosis. Journal of Controlled Release [Internet]. 2006;113(1):23–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33744535630&doi=10.1016%252fj.jconrel.2006.03.010&partnerID=40&md5=5e473c53fd5454b794e1508443217afb

48.

Epstein H, Afergan E, Moise T, Richter Y, Rudich Y, Golomb G. Number-concentration of nanoparticles in liposomal and polymeric multiparticulate preparations: Empirical and calculation methods. Biomaterials [Internet]. 2006;27(4):651–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-26844457912&doi=10.1016%252fj.biomaterials.2005.06.006&partnerID=40&md5=14f2169cb7efe6379f1e7e6ffedea473

49.

Banai S, Chorny M, Gertz SD, Fishbein I, Gao J, Perez L, et al. Erratum: Locally delivered nanoencapsulated tyrphostin (AGL-2043) reduces neointima formation in balloon-injured rat carotid and stented porcine coronary arteries (Biomaterials (2005) 26 (451-461) DOI: 10.1016/j.biomaterials.2004.02. 040). Biomaterials [Internet]. 2005;26(23):4898–901. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-20044372876&doi=10.1016%252fj.biomaterials.2005.01.032&partnerID=40&md5=b25a1375a8e896e14cec7caecaf654fa

50.

Bejjani RA, BenEzra D, Cohen H, Rieger J, Andrieu C, Jeanny JC, et al. Nanoparticles for gene delivery to retinal pigment epithelial cells. Molecular Vision [Internet]. 2005;11:124–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-21644468948&partnerID=40&md5=ee23bf9e47ffd773c40afcdee02377b9

51.

Banai S, Chorny M, Gertz SD, Fishbein I, Gao J, Perez L, et al. Locally delivered nanoencapsulated tyrphostin (AGL-2043) reduces neointima formation in balloon-injured rat carotid and stented porcine coronary arteries. Biomaterials [Internet]. 2005;26(4):451–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242716834&doi=10.1016%252fj.biomaterials.2004.02.040&partnerID=40&md5=00a227f7fb5ae5b5a7280bdae450de42

52.

Banai S, Gertz SD, Gavish L, Chorny M, Perez LS, Lazarovichi G, et al. Tyrphostin AGL-2043 eluting stent reduces neointima formation in porcine coronary arteries. Cardiovascular Research [Internet]. 2004;64(1):165–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-4444231182&doi=10.1016%252fj.cardiores.2004.06.013&partnerID=40&md5=816c96dd4981ba2a88016185df56588d

53.

Cohen-Sacks H, Elazar V, Gao J, Golomb A, Adwan H, Korchov N, et al. Delivery and expression of pDNA embedded in collagen matrices. Journal of Controlled Release [Internet]. 2004;95(2):309–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-1242271280&doi=10.1016%252fj.jconrel.2003.11.001&partnerID=40&md5=0fdea78f76f166cc917d9f9e196bdf39

54.

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Teomim D, Fishbien I, Golomb G, Orloff L, Mayberg M, Domb AJ. Perivascular delivery of heparin for the reduction of smooth muscle cell proliferation after endothelial injury. Journal of Controlled Release [Internet]. 1999;60(1):129–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033019739&doi=10.1016%2fS0168-3659%2899%2900071-1&partnerID=40&md5=fbfb7e0049c89afb6da1aa6f1960f8ab

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Mathew M, Fowler BO, Breuer E, Golomb G, Alferiev IS, Eidelman N. Synthesis, Characterization, and Crystal Structure of Dicalcium Glutarylbis(phosphonate) Dihydrate: A Covalently Pillared Layer Structure with the Potential for Epitaxial Growth on Hydroxyapatite. Inorganic Chemistry [Internet]. 1998;37(25):6485–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000574294&doi=10.1021%252fic980374h&partnerID=40&md5=160985812547c731e88b813fbf705ff7

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Orloff LA, Domb AJ, Teomim D, Fishbein I, Golomb G. Biodegradable implant strategies for inhibition of restenosis. Advanced Drug Delivery Reviews [Internet]. 1997;24(1):3–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031568915&doi=10.1016%2fS0169-409X%2896%2900478-4&partnerID=40&md5=4af833a746e7d00c34986eff84b21962

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Mishaly D, Fishbein I, Moscovitz D, Golomb G. Site-specific delivery of colchicine in rat carotid artery model of restenosis. Journal of Controlled Release [Internet]. 1997;45(1):65–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031015567&doi=10.1016%2fS0168-3659%2896%2901546-5&partnerID=40&md5=4092331737e7d5d8c076b81a26c61172

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Muller DWM, Gordon D, Topol EJ, Levy RJ, Golomb G. Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting. American Heart Journal [Internet]. 1996;131(2):211–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030065126&doi=10.1016%2fS0002-8703%2896%2990343-9&partnerID=40&md5=6cf4cf56ab451ee913eda3be4754e735

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Golomb G. Contemporary approaches for calcitonin therapy. Proceedings of the Controlled Release Society [Internet]. 1996;(23):176–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029810483&partnerID=40&md5=036d9cf18e52126f259c958f1949de27

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Ezra A, Breuer E, Amidon G, Hoffman A, Ornoy A, Patlas N, et al. Peptidyl prodrug of bisphosphonates for improved oral absorption. Proceedings of the Controlled Release Society [Internet]. 1996;(23):83–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029790564&partnerID=40&md5=0188da4715da696c506c80abcae44150

109.

Huffman A, Shaked I, Avramoff A, Golomb G. Pharmacokinetics and pharmacodynamics of trans-endometrial administered peptides and macromolecules. Advanced Drug Delivery Reviews [Internet]. 1995;17(2):191–203. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029394918&doi=10.1016%2f0169-409X%2895%2900087-N&partnerID=40&md5=0d5699446bbfd23e39a85d25fa2f1065

110.

Golomb G, Shaked I, Hoffman A. Intrauterine administration of peptide drugs for systemic effect. Advanced Drug Delivery Reviews [Internet]. 1995;17(2):179–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029394877&doi=10.1016%2f0169-409X%2895%2900086-M&partnerID=40&md5=0c7c59c68996f39e7bbd94e5dbd661a0

111.

Golomb G. Preface. Advanced Drug Delivery Reviews [Internet]. 1995;17(2):149–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028871646&doi=10.1016%2f0169-409X%2895%2990010-S&partnerID=40&md5=f46dfcd32dcf622501f99d3ccd85d117

112.

Van Gelder JM, Breuer E, Ornoy A, Schlossman A, Patlas N, Golomb G. Anticalcification and antiresorption effects of bisacylphosphonates. Bone [Internet]. 1995;16(5):511–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029162805&doi=10.1016%2f8756-3282%2895%2900081-N&partnerID=40&md5=c0a31af7a13947e846e9f94d01cefc7e

113.

Golomb G, Fishbein I, Banai S, Moscovitz D, Mishaly D, Gertz SD, et al. Inhibition of restenosis in a rat model by perivascular delivery of a tyrphostin compound. Proceedings of the Controlled Release Society [Internet]. 1995;(22):151–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029155810&partnerID=40&md5=001dcd41101a92e748e98089dca5e081

114.

Hoffman A, Shaked I, Nyska A, Avramoff A, Golomb G. Trans-endometrial route of drug administration: In-vitro and in-vivo evaluation. Proceedings of the Controlled Release Society [Internet]. 1995;(22):568–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029091041&partnerID=40&md5=657dad9f4905c3f3ffdba75e5ee600a2

115.

Hoffman A, Nyska A, Avramoff A, Golomb G. Continuous versus pulsatile administration of erythropoietin (EPO) via the uterus in anemic rats. International Journal of Pharmaceutics [Internet]. 1994;111(2):197–202. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027933349&doi=10.1016%2f0378-5173%2894%2900144-8&partnerID=40&md5=2aba816c891fc3662416e84cb9b294f0

116.

Villa AE, Guzman LA, Chen W, Golomb G, Levy RJ, Topol EJ. Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty. Journal of Clinical Investigation [Internet]. 1994;93(3):1243–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028223999&doi=10.1172%252fJCI117078&partnerID=40&md5=b87ccfc104412cd4cd39c3c3961add63

117.

Muller DWM, Golomb G, Gordon D, Levy RJ. Site-specific dexamethasone delivery for the prevention of neointimal thickening after vascular stent implantation. Coronary Artery Disease [Internet]. 1994;5(5):435–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028223812&doi=10.1097%252f00019501-199405000-00010&partnerID=40&md5=331621697a3092863317c9bd051a9af5

118.

Golomb G, Niska A, Avramoff A, Shaked I, Hoffman A. Intrauterine controlled delivery of peptides for systemic effect. Proceedings of the Controlled Release Society [Internet]. 1994;(21):38–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028091535&partnerID=40&md5=a7bfdf0d1a60a7e5b10ad5deef2a4eb5

119.

Bialer M, Hadad S, Golomb G, Barel S, Samara E, Salach OA, et al. Pharmacokinetic analysis of two new sustained‐release products of diltiazem designed for twice‐and once‐daily treatment. Biopharmaceutics & Drug Disposition [Internet]. 1994;15(1):45–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028053169&doi=10.1002%252fbdd.2510150104&partnerID=40&md5=9539d7c01955580b55054583f239bc5c

120.

Breuer E, Golomb G, Hoffman A, Schlossman A, Van Gelder JM, Saadeh H, et al. In Vitro and In Vivo Inhibition of Hydroxyapatite Formation and Dissolution by Bisacylphosphonates and Bishydroxyiminophosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements [Internet]. 1993;76(1–4):167–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84950071810&doi=10.1080%252f10426509308032385&partnerID=40&md5=e717dd6dabd9cccf2f56a6ea98714f78

121.

Golomb G, Barashi A, Wagner D, Nachmias O. In-vitro and in-vivo models for the study of the relationship between hydrophilicity and calcification of polymeric and collageneous biornaterials. Clinical Materials [Internet]. 1993;13(1–4):61–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027272430&doi=10.1016%2f0267-6605%2893%2990092-L&partnerID=40&md5=e045117c9b9ba59bd0b763130571e480

122.

Golomb G, Avramoff A, Hoffman A. A New Route of Drug Administration: Intrauterine Delivery of Insulin and Calcitonin. Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists [Internet]. 1993;10(6):828–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027155556&doi=10.1023%252fA%253a1018948924992&partnerID=40&md5=d721de2e8b0fb607e15228ab34860934

123.

Levy RJ, Golomb G, Labhasetwar V. New frontiers in cardiovascular polymeric controlled release. In: Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering [Internet]. 1992. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026993034&partnerID=40&md5=a6acbfe27f1656b31bbcb9d84ef993e8

124.

Schoen FJ, Golomb G, Levy RJ. Calcification of bioprosthetic heart valves: a perspective on models. The Journal of heart valve disease [Internet]. 1992;1(1):110–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026911171&partnerID=40&md5=b275c481db924e8baa5c7d7409346106

125.

Golomb G. Calcification of polyurethane-based biomaterials implanted subcutaneously in rats: role of porosity and fluid absorption in the mechanism of mineralization. Journal of Materials Science: Materials in Medicine [Internet]. 1992;3(4):272–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0008505120&doi=10.1007%252fBF00705292&partnerID=40&md5=b6edb5c040fef7721d028e598a0b4367

126.

Golomb G, Schlossman A, Eitan Y, Saadeh H, Van Gelder JM, Breuer E. In vitro and in vivo anticalcification effects of novel bishydroxyiminophosphonates. Journal of Pharmaceutical Sciences [Internet]. 1992;81(10):1004–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027080882&doi=10.1002%252fjps.2600811009&partnerID=40&md5=4fbb250683850ee1e7a4cd5192a56cd0

127.

Golomb G, Eitan Y, Hoffman A. Measurement of Serum [3H]Tetracycline Kinetics and Indices of Kidney Function Facilitate Study of the Activity and Toxic Effects of Bisphosphonates in Bone Resorption. Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists [Internet]. 1992;9(8):1018–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026611382&doi=10.1023%252fA%253a1015898226519&partnerID=40&md5=31a50c4f0b2ce481cf2c15782072d103

128.

Golomb G, Lewinstein I, Ezra V, Schoen FJ. Mechanical properties and histology of charge modified bioprosthetic tissue resistant to calcification. Biomaterials [Internet]. 1992;13(6):353–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026573356&doi=10.1016%2f0142-9612%2892%2990039-Q&partnerID=40&md5=6ba9e40e3342d32c280b59f2c775e033

129.

Golomb G, Ezra V. Covalent binding of protamine by glutaraldehyde to bioprosthetic tissue: Characterization and anticalcification effect. Biomaterials, Artificial Cells and Immobilization Biotechnology [Internet]. 1992;20(1):31–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026554920&doi=10.3109%252f10731199209117856&partnerID=40&md5=305348ead1ba66ede1ccac058f7e6dd5

130.

Golomb G, Schlossman A, Saadeh H, Levi M, Van Gelder JM, Breuer E. Bisacylphosphonates Inhibit Hydroxyapatite Formation and Dissolution in Vitro and Dystrophic Calcification in Vivo. Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists [Internet]. 1992;9(1):143–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026542421&doi=10.1023%252fA%253a1018956516640&partnerID=40&md5=864c0e8fdc45a43cd71b91cd1678d232

131.

Golomb G, Wagner D. Characterization and anticalcification effects of implantable polyurethane matrices containing amorphous dispersion of bisphosphonic acid. Clinical Materials [Internet]. 1991;8(1–2):33–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026348758&doi=10.1016%2f0267-6605%2891%2990007-3&partnerID=40&md5=f263737016597986975e00a30245beeb

132.

Golomb G, Shpigelman A. Prevention of bacterial colonization on polyurethane in vitro by incorporated antibacterial agent. Journal of Biomedical Materials Research [Internet]. 1991;25(8):937–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026205070&doi=10.1002%252fjbm.820250803&partnerID=40&md5=abffe5cb2a67d12b7885044d39e4bce1

133.

Golomb G, Ezra V. Prevention of bioprosthetic heart valve tissue calcification by charge modification: Effects of protamine binding by formaldehyde3. Journal of Biomedical Materials Research [Internet]. 1991;25(1):85–98. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026083870&doi=10.1002%252fjbm.820250107&partnerID=40&md5=fb537e6467738b6c0d477d2304e6c215

134.

Golomb G, Wagner D. Development of a new in vitro model for studying implantable polyurethane calcification. Biomaterials [Internet]. 1991;12(4):397–405. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025803939&doi=10.1016%2f0142-9612%2891%2990008-X&partnerID=40&md5=5e41b347f6c1e66b89f23cbc24759970

135.

Golomb G, Fisher P, Rahamim E. The relationship between drug release rate, particle size and swelling of silicone matrices. Journal of Controlled Release [Internet]. 1990;12(2):121–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025269842&doi=10.1016%2f0168-3659%2890%2990088-B&partnerID=40&md5=3f9dde625bc74afa4b6348e88f963160

136.

Levy RJ, Johnston TP, Sintov A, Golomb G. Controlled release implants for cardiovascular disease. Journal of Controlled Release [Internet]. 1990;11(1–3):245–54. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025159222&doi=10.1016%2f0168-3659%2890%2990137-I&partnerID=40&md5=00a10bbed85f5331aa42c59937eeab0f

137.

Johnston TP, Bove EL, Bolling SF, Schoen FJ, Boyd JA, Golomb G, et al. Local controlled release of 1-hydroxyethylidene diphosphonate using silicone-rubber matrices. Effects of sterilization on in vitro release and in vivo efficacy. ASAIO Transactions [Internet]. 1988;34(3):835–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023816714&partnerID=40&md5=6c4ab16516c9962640a450a8436cad41

138.

Golomb G, Schoen FJ, Smith MS, Linden J, Dixon M, Levy RJ. The role of glutaraldehyde-induced cross-links in calcification of bovine pericardium used in cardiac valve bioprostheses. American Journal of Pathology [Internet]. 1987;127(1):122–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023184262&partnerID=40&md5=08f343ade0631013771067b661bd18ab

139.

Golomb G. Controlled Release of Diphosphonates from Synthetic Polymers to Inhibit Calcification. Journal of Biomaterials Applications [Internet]. 1987;2(2):266–89. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023434534&doi=10.1177%252f088532828700200205&partnerID=40&md5=336f2aeee95697d82e15499a109b6f09

140.

Golomb G, Dixon M, Smith MS, Schoen FJ, Levy RJ. Controlled‐release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: Release rate modulation with silicone matrices via drug solubility and membrane coating. Journal of Pharmaceutical Sciences [Internet]. 1987;76(4):271–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023227630&doi=10.1002%252fjps.2600760402&partnerID=40&md5=75322368c46ab88fcb2e82ba700c3014

141.

Golomb G, Dixon M, Smith MS, Schoen FJ, Levy RJ. Inhibition of bioprosthetic heart valve calcification by sustained local delivery of Ca and Na diphosphonate via controlled release matrices. ASAIO transactions / American Society for Artificial Internal Organs [Internet]. 1986;32(1):587–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022753544&partnerID=40&md5=2d1492133b369c70784d6df87b511ea7

142.

Golomb G, Langer R, Schoen FJ, Smith MS, Choi YM, Levy RJ. Controlled release of diphosphonate to inhibit bioprosthetic heart valve calcification: Dose-response and mechanistic studies. Journal of Controlled Release [Internet]. 1986;4(3):181–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023035506&doi=10.1016%2f0168-3659%2886%2990002-7&partnerID=40&md5=b941b93ff1a19086b9d497cb2c659eec

143.

Stabholz A, Sela MN, Friedman M, Golomb G, Soskolne A. Clinical and microbiological effects of sustained release chlorhexidine in periodontal pockets. Journal of Clinical Periodontology [Internet]. 1986;13(8):783–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023013474&doi=10.1111%252fj.1600-051X.1986.tb00882.x&partnerID=40&md5=51e44b21f665f86f48bdbd2517e4e9f9

144.

Levy RJ, Shoen FJ, Golomb G. Bioprosthetic heart valve calcification: Clinical features, pathobiology, and prospects for prevention. Critical Reviews in Biocompatibility [Internet]. 1986;2(2):147–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022966729&partnerID=40&md5=c6de8d8dbbbd9f29f53a8b63784ee91a

145.

Levy RJ, Golomb G, Wolfrum J, Lund SA, Schoen FJ, Langer R. Local controlled-release of diphosphonates from ethylenevinylacetate matrices prevents bioprosthetic heart valve calcification. Transactions - American Society for Artificial Internal Organs [Internet]. 1985;31:459–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022177375&partnerID=40&md5=cbde27adfb3d0cec9e86f5b60542f39f

146.

Friedman M, Brayer L, Golomb G, Hiller H. Prevention of plaque accumulation by local application of a sustained release delivery system of chlorhexidine. Journal of Controlled Release [Internet]. 1984;1(2):157–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021673293&doi=10.1016%2f0168-3659%2884%2990009-9&partnerID=40&md5=e5276d26e48f7a7c194dcf81df4e7df3

147.

HIRSCHFELD Z, FRIEDMAN M, GOLOMB G, BEN‐YAACOV D. New sustained release dosage form of chlorhexidine for dental use: use for plaque control in partial denture wearers. Journal of Oral Rehabilitation [Internet]. 1984;11(5):477–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021200290&doi=10.1111%252fj.1365-2842.1984.tb00600.x&partnerID=40&md5=ec51014663c33548f11184fe9ee79587

148.

Golomb G, Friedman M, Soskolne A, Stabholz A, Sela MN. Sustained Release Device Containing Metronidazole for Periodontal Use. Journal of Dental Research [Internet]. 1984;63(9):1149–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021144771&doi=10.1177%252f00220345840630091101&partnerID=40&md5=0d13344341a3f91c39bfa210829d6274

149.

Soskolne A, Golomb G, Friedman M, Sela MN. New sustained release dosage form of chlorhexidine for dental use: II. Use in periodontal therapy. Journal of Periodontal Research [Internet]. 1983;18(3):330–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020602007&doi=10.1111%252fj.1600-0765.1983.tb00368.x&partnerID=40&md5=e62d831fd088154b6da8b969b92ec9c5

150.

Friedman M, Golomb G. New sustained release dosage form of chlorhexidine for dental use: I. Development and kinetics of release. Journal of Periodontal Research [Internet]. 1982;17(3):323–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020408104&doi=10.1111%252fj.1600-0765.1982.tb01160.x&partnerID=40&md5=1adc8d264173a9ddb19a8f6f93b8b34e

151.

Soskolne WA, Friedman M, Golomb G, Sela M. Sustained release reservoirs of chlorhexidine in periodontal pockets. Journal of Dental Research [Internet]. 1982;61(Abs.):No. 856. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020047917&partnerID=40&md5=c9d222791310cd4c889ae19a39915dd0

152.

Friedman M, Golomb G. Dissolution rate of fluorides: Quality test of dentifrices. Journal of Dental Research [Internet]. 1980;59(SPEC.1SS. DI):1879. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019296129&partnerID=40&md5=70a09ca673d7937be56c86817670788c

153.

Friedman M, Golomb G, Brayer L, Ch. H. Sustained release chlorhexidine preparations for topical use. Journal of Dental Research [Internet]. 1980;59(SPEC. ISSUE B):No. 72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019194934&partnerID=40&md5=da44a1bad30204908d472de21a96c4cf