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School of Pharmacy : Weinstock-Rosin Marta

Researchers

 Last updated Septmber 2023 - School of Pharmacy

List of Publications

1.            Reichert, F. et al. Ladostigil Reduces the Adenoside Triphosphate/Lipopolysaccharide-Induced Secretion of Pro-Inflammatory Cytokines from Microglia and Modulate-Immune Regulators, TNFAIP3, and EGR1. Biomolecules 14, (2024).

2.            Dan, R., Weinstock, M. & Goelman, G. Emotional states as distinct configurations of functional brain networks. Cereb. Cortex 33, 5727–5739 (2023).

3.            Yehezkel, A. S. et al. AN1284 attenuates steatosis, lipogenesis, and fibrosis in mice with pre-existing non-alcoholic steatohepatitis and directly affects aryl hydrocarbon receptor in a hepatic cell line. Front. Endocrinol. (Lausanne). 14, (2023).

4.            Zohar, K. et al. Coordinated Transcriptional Waves Define the Inflammatory Response of Primary Microglial Culture. Int. J. Mol. Sci. 24, (2023).

5.            Weitman, M. et al. Comparison of the tissue distribution and metabolism of AN1284, a potent anti-inflammatory agent, after subcutaneous and oral administration in mice. Naunyn. Schmiedebergs. Arch. Pharmacol. 394, 2077–2089 (2021).

6.            Weinstock, M. Linking citalopram, serotonin reuptake inhibitors, and depressed pregnant women. in The Neuroscience of Depression, 1st Edition: Volume 1-2 vols 1–2 V1-325-V1-336 (Elsevier, 2021).

7.            Weinstock, M. Linking citalopram, serotonin reuptake inhibitors, and depressed pregnant women. in The Neuroscience of Depression: Features, Diagnosis, and Treatment 325–336 (Elsevier, 2021). doi:10.1016/B978-0-12-817933-8.00092-X.

8.            Linial, M., Stern, A. & Weinstock, M. Effect of ladostigil treatment of aging rats on gene expression in four brain areas associated with regulation of memory: Selective changes by ladostigil in gene expression in aging brain. Neuropharmacology 177, (2020).

9.            Dan, R. et al. Trait-related changes in brain network topology in premenstrual dysphoric disorder. Horm. Behav. 124, (2020).

10.          Permyakova, A. et al. A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities. Front. Endocrinol. (Lausanne). 11, (2020).

11.          Schneider, L. S. et al. Low-dose ladostigil for mild cognitive impairment: A phase 2 placebo-controlled clinical trial. Neurology 93, e1474–e1484 (2019).

12.          Shoham, S., Linial, M. & Weinstock, M. Age-Induced Spatial Memory Deficits in Rats Are Correlated with Specific Brain Region Alterations in Microglial Morphology and Gene Expression. J. Neuroimmune Pharmacol. 14, 251–262 (2019).

13.          Dan, R. et al. Sex differences during emotion processing are dependent on the menstrual cycle phase. Psychoneuroendocrinology 100, 85–95 (2019).

14.          Zeeli, S. et al. Synthesis and Biological Evaluation of Derivatives of Indoline as Highly Potent Antioxidant and Anti-inflammatory Agents. J. Med. Chem. 61, 4004–4019 (2018).

15.          Finkin-Groner, E., Finkin, S., Zeeli, S. & Weinstock, M. Indoline derivatives mitigate liver damage in a mouse model of acute liver injury. Pharmacol. Reports 69, 894–902 (2017).

16.          Shifrin, H., Mouhadeb, O., Gluck, N., Varol, C. & Weinstock, M. Cholinergic Anti-Inflammatory Pathway Does Not Contribute to Prevention of Ulcerative Colitis by Novel Indoline Carbamates. J. Neuroimmune Pharmacol. 12, 484–491 (2017).

17.          Weinstock, M. Prenatal stressors in rodents: Effects on behavior. Neurobiol. Stress 6, 3–13 (2017).

18.          Shifrin, H., Moradov, D., Bejar, C., Schorer-Apelbaum, D. & Weinstock, M. Novel indoline derivatives prevent inflammation and ulceration in dinitro-benzene sulfonic acid-induced colitis in rats. Pharmacol. Reports 68, 1312–1318 (2016).

19.          Barbie-Shoshani, Y., Shoham, S., Bejar, C. & Weinstock, M. Sex-Specific Effects of Prenatal Stress on Memory and Markers of Neuronal Activity in Juvenile Rats. Dev. Neurosci. 38, 206–219 (2016).

20.          Zohar, I., Shoham, S. & Weinstock, M. Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive-like behaviour and serotonergic transmission in adult rat offspring. Eur. J. Neurosci. 43, 590–600 (2016).

21.          Zohar, I., Dosoretz-Abittan, L., Shoham, S. & Weinstock, M. Sex dependent reduction by prenatal stress of the expression of 5HT1A receptors in the prefrontal cortex and CRF type 2 receptors in the raphe nucleus in rats: Reversal by citalopram. Psychopharmacology (Berl). 232, 1643–1653 (2015).

22.          Moradov, D. et al. Dose-limiting inhibition of acetylcholinesterase by ladostigil results from the rapid formation and fast hydrolysis of the drug-enzyme complex formed by its major metabolite, R-MCPAI. Biochem. Pharmacol. 94, 164–172 (2015).

23.          Moradov, D. et al. The anti-inflammatory activity of a novel fused-cyclopentenone phosphonate and its potential in the local treatment of experimental colitis. Gastroenterol. Res. Pract. 2015, (2015).

24.          Weinstock, M. Changes induced by prenatal stress in behavior and brain morphology: Can they be prevented or reversed? Advances in Neurobiology vol. 10 3–25 (2015).

25.          Finkin-Groner, E. et al. Indoline-3-propionate and 3-aminopropyl carbamates reduce lung injury and pro-inflammatory cytokines induced in mice by LPS. Br. J. Pharmacol. 172, 1101–1113 (2015).

26.          Goelman, G., Ilinca, R., Zohar, I. & Weinstock, M. Functional connectivity in prenatally stressed rats with and without maternal treatment with ladostigil, a brain-selective monoamine oxidase inhibitor. Eur. J. Neurosci. 40, 2734–2743 (2014).

27.          Furman, S. et al. Synthesis and in vitro evaluation of anti-inflammatory activity of ester and amine derivatives of indoline in RAW 264.7 and peritoneal macrophages. Bioorganic Med. Chem. Lett. 24, 2283–2287 (2014).

28.          Weinstock, M. et al. Dose-dependent effects of ladostigil on microglial activation and cognition in aged rats. J. Neuroimmune Pharmacol. 8, 345–355 (2013).

29.          Shifrin, H., Nadler-Milbauer, M., Shoham, S. & Weinstock, M. Rivastigmine Alleviates Experimentally Induced Colitis in Mice and Rats by Acting at Central and Peripheral Sites to Modulate Immune Responses. PLoS One 8, (2013).

30.          Yanovsky, I. et al. Carbamate derivatives of indolines as cholinesterase inhibitors and antioxidants for the treatment of Alzheimer’s disease. J. Med. Chem. 55, 10700–10715 (2012).

31.          Panarsky, R., Luques, L. & Weinstock, M. Anti-inflammatory effects of ladostigil and its metabolites in aged rat brain and in microglial cells. J. Neuroimmune Pharmacol. 7, 488–498 (2012).

32.          Weinstock, M. Sex-dependent changes induced by prenatal stress in cortical and hippocampal morphology and behaviour in rats: An update. Stress 14, 604–613 (2011).

33.          Bock, J., Murmu, M. S., Biala, Y., Weinstock, M. & Braun, K. Prenatal stress and neonatal handling induce sex-specific changes in dendritic complexity and dendritic spine density in hippocampal subregions of prepubertal rats. Neuroscience 193, 34–43 (2011).

34.          Biala, Y. N., Bogoch, Y., Bejar, C., Linial, M. & Weinstock, M. Prenatal stress diminishes gender differences in behavior and in expression of hippocampal synaptic genes and proteins in rats. Hippocampus 21, 1114–1125 (2011).

35.          Weinstock, M., Luques, L., Poltyrev, T., Bejar, C. & Shoham, S. Ladostigil prevents age-related glial activation and spatial memory deficits in rats. Neurobiol. Aging 32, 1069–1078 (2011).

36.          Zohar, I. & Weinstock, M. Differential Effect of Prenatal Stress on the Expression of Cortiocotrophin-Releasing Hormone and its Receptors in the Hypothalamus and Amygdala in Male and Female Rats. J. Neuroendocrinol. 23, 320–328 (2011).

37.          Salomon, S., Bejar, C., Schorer-Apelbaum, D. & Weinstock, M. Corticosterone Mediates Some but Not Other Behavioural Changes Induced by Prenatal Stress in Rats. J. Neuroendocrinol. 23, 118–128 (2011).

38.          Weinstock, M. Intrauterine factors as determinants of depressive disorder. Isr. J. Psychiatry Relat. Sci. 47, 36–45 (2010).

39.          Weinstock, M. Contribution of Early Life Stress to Anxiety Disorder. in Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses 189–205 (John Wiley and Sons, 2009). doi:10.1002/9783527628346.ch10.

40.          Nizri, E. et al. Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine. J. Neuroimmunol. 203, 12–22 (2008).

41.          Weinstock, M. & Groner, E. Rational design of a drug for Alzheimer’s disease with cholinesterase inhibitory and neuroprotective activity. Chem. Biol. Interact. 175, 216–221 (2008).

42.          Weinstock, M. The long-term behavioural consequences of prenatal stress. Neurosci. Biobehav. Rev. 32, 1073–1086 (2008).

43.          Weinstock, M. Gender differences in the effects of prenatal stress on brain development and behaviour. Neurochem. Res. 32, 1730–1740 (2007).

44.          Luques, L., Shoham, S. & Weinstock, M. Chronic brain cytochrome oxidase inhibition selectively alters hippocampal cholinergic innervation and impairs memory: Prevention by ladostigil. Exp. Neurol. 206, 209–219 (2007).

45.          Groner, E. et al. The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates. Mol. Pharmacol. 71, 1610–1617 (2007).

46.          Bogoch, Y., Biala, Y. N., Linial, M. & Weinstock, M. Anxiety induced by prenatal stress is associated with suppression of hippocampal genes involved in synaptic function. J. Neurochem. 101, 1018–1030 (2007).

47.          Yaka, R., Salomon, S., Matzner, H. & Weinstock, M. Effect of varied gestational stress on acquisition of spatial memory, hippocampal LTP and synaptic proteins in juvenile male rats. Behav. Brain Res. 179, 126–132 (2007).

48.          Shoham, S., Bejar, C., Kovalev, E., Schorer-Apelbaum, D. & Weinstock, M. Ladostigil prevents gliosis, oxidative-nitrative stress and memory deficits induced by intracerebroventricular injection of streptozotocin in rats. Neuropharmacology 52, 836–843 (2007).

49.          Zagron, G. & Weinstock, M. Maternal adrenal hormone secretion mediates behavioural alterations induced by prenatal stress in male and female rats. Behav. Brain Res. 175, 323–328 (2006).

50.          Murmu, M. S. et al. Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy. Eur. J. Neurosci. 24, 1477–1487 (2006).

51.          Weinstock, M., Luques, L., Bejar, C. & Shoham, S. Ladostigil, a novel multifunctional drug for the treatment of dementia co-morbid with depression. Journal of Neural Transmission, Supplement 443–446 (2006) doi:10.1007/978-3-211-45295-0_67.

52.          Poltyrev, T., Gorodetsky, E., Bejar, C., Schorer-Apelbaum, D. & Weinstock, M. Effect of chronic treatment with ladostigil (TV-3326) on anxiogenic and depressive-like behaviour and on activity of the hypothalamic-pituitary-adrenal axis in male and female prenatally stressed rats. Psychopharmacology (Berl). 181, 118–125 (2005).

53.          Weinstock, M. The potential influence of maternal stress hormones on development and mental health of the offspring. Brain. Behav. Immun. 19, 296–308 (2005).

54.          Beilin, B., Bessler, H., Papismedov, L., Weinstock, M. & Shavit, Y. Continuous physostigmine combined with morphine-based patient-controlled analgesia in the postoperative period. Acta Anaesthesiol. Scand. 49, 78–84 (2005).

55.          Lerman, L., Weinstock-Rosin, M. & Nudelman, A. An improved synthesis of hydroxyindoles. Synthesis (Stuttg). 3043–3046 (2004) doi:10.1055/s-2004-834924.

56.          Weinstock, M. & Shoham, S. Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J. Neural Transm. 111, 347–366 (2004).

57.          Poltyrev, T. & Weinstock, M. Gender difference in the prevention of hyperanxiety in adult prenatally stressed rats by chronic treatment with amitriptyline. Psychopharmacology (Berl). 171, 270–276 (2004).

58.          Youdim, M. B. H. & Weinstock, M. Therapeutic Applications of Selective and Non-Selective Inhibitors of Monoamine Oxidase A and B that do not Cause Significant Tyramine Potentiation. Neurotoxicology 25, 243–250 (2004).

59.          Drigues, N., Poltyrev, T., Bejar, C., Weinstock, M. & Youdim, M. B. H. cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs. J. Neural Transm. 110, 1413–1436 (2003).

60.          Sagi, Y., Weinstock, M. & Youdim, M. B. H. Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor. J. Neurochem. 86, 290–297 (2003).

61.          Maruyama, W., Weinstock, M., Youdim, M. B. H., Nagai, M. & Naoi, M. Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor. Neurosci. Lett. 341, 233–236 (2003).

62.          Shoham, S., Bejar, C., Kovalev, E. & Weinstock, M. Intracerebroventricular injection of streptozotocin causes neurotoxicity to myelin that contributes to spatial memory deficits in rats. Exp. Neurol. 184, 1043–1052 (2003).

63.          Youdim, M. B. H., Amit, T., Bar-Am, O., Weinstock, M. & Yogev-Falach, M. Amyloid processing and signal transduction properties of antiparkinson-antialzheimer neuroprotective drugs rasagiline and TV3326. Annals of the New York Academy of Sciences vol. 993 378–386 (2003).

64.          Weinstock, M. et al. A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson’s disease. Prog. Neuro-Psychopharmacology Biol. Psychiatry 27, 555–561 (2003).

65.          Sterling, J. et al. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer’s disease. J. Med. Chem. 45, 5260–5279 (2002).

66.          Weinstock, M. et al. Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits. Neuropharmacology 43, 999–1005 (2002).

67.          Weinstock, M. Can the behaviour abnormalities induced by gestational stress in rats be prevented or reversed? Stress 5, 167–176 (2002).

68.          Youdim, M. B. H. & Weinstock, M. Novel neuroprotective anti-Alzheimer drugs with anti-depressant activity derived from the anti-Parkinson drug, rasagiline. Mech. Ageing Dev. 123, 1081–1086 (2002).

69.          Weinstock, M., Poltyrev, T., Bejar, C. & Youdim, M. B. Effect of TV3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression. Psychopharmacology (Berl). 160, 318–324 (2002).

70.          Yogev-Falach, M., Amit, T., Bar-Am, O., Weinstock, M. & Youdim, M. B. Involvement of MAP kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline. FASEB J. 16, 1674–1676 (2002).

71.          Wang, R.-H., Schorer-Apelbaum, D. & Weinstock, M. Testosterone mediates sex difference in hypothermia and cholinesterase inhibition by rivastigmine. Eur. J. Pharmacol. 433, 73–79 (2001).

72.          Youdim, M. B. H. & Weinstock, M. Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. Cell. Mol. Neurobiol. 21, 555–573 (2001).

73.          Weinstock, M. Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog. Neurobiol. 65, 427–451 (2001).

74.          Wang, R. H. & Weinstock, M. Steroid hormones mediate sex difference in brain levels of tacrine and its hypothermic effect in the rat. Neuropharmacology 41, 887–894 (2001).

75.          Weinstock, M. Effects of maternal stress on development and behaviour in rat offspring. Stress 4, 157–167 (2001).

76.          Youdim, M. B. H., Wadia, A., Tatton, W. & Weinstock, M. The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo. Annals of the New York Academy of Sciences vol. 939 450–458 (2001).

77.          Weinstock, M. et al. Neuroprotective effects of novel cholinesterase inhibitors derived from rasagiline as potential anti-Alzheimer drugs. Annals of the New York Academy of Sciences vol. 939 148–161 (2001).

78.          Wang, R. H., Bejar, C. & Weinstock, M. Gender differences in the effect of rivastigmine on brain cholinesterase activity and cognitive function in rats. Neuropharmacology 39, 497–506 (2000).

79.          Weinstock, M. et al. TV3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activities for the treatment of Alzheimer’s disease. J. Neural Transm. Suppl. 60, 157–169 (2000).

80.          Weinstock, M., Goren, T. & Youdim, M. B. H. Development of a novel neuroprotective drug (TV3326) for the treatment of Alzheimer’s disease, with cholinesterase and monoamine oxidase inhibitory activities. Drug Dev. Res. 50, 216–222 (2000).

81.          Weinstock, M. Selectivity of cholinesterase inhibition: Clinical implications for the treatment of Alzheimer’s disease. CNS Drugs 12, 307–323 (1999).

82.          Bejar, C., Wang, R.-H. & Weinstock, M. Effect of rivastigmine on scopolamine-induced memory impairment in rats. Eur. J. Pharmacol. 383, 231–240 (1999).

83.          Poltyrev, T. & Weinstock, M. Effect of Gestational Stress pa Maternal Behavior in Response to Cage Transfer and Handling of Pups in Two Strains of Rat. Stress 3, 85–95 (1999).

84.          Finberg, J. P., Lamensdorf, I., Weinstock, M., Schwartz, M. & Youdim, M. B. Pharmacology of rasagiline (N-propargyl-1R-aminoindan). Adv. Neurol. 80, 495–499 (1999).

85.          Huang, W., Chen, Y., Shohami, E. & Weinstock, M. Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse. Eur. J. Pharmacol. 366, 127–135 (1999).

86.          Weinstock, M., Poltyrev, T., Schorer-Apelbaum, D., Men, D. & McCarty, R. Effect of prenatal stress on plasma corticosterone and catecholamines in response to footshock in rats. Physiol. Behav. 64, 439–444 (1998).

87.          Weinstock, M., Razin, M., Schorer-apelbaum, D., Men, D. & Mccarty, R. Gender differences in sympathoadrenal activity in rats at rest and in response to footshock stress. Int. J. Dev. Neurosci. 16, 289–295 (1998).

88.          Kay, G., Tarcic, N., Poltyrev, T. & Weinstock, M. Prenatal stress depresses immune function in rats. Physiol. Behav. 63, 397–402 (1998).

89.          Maybaum, N., Gorodetsky, E. & Weinstock, M. Relationship between arterial baroreflex, cardiopulmonary vagal reflex and renal natriuretic response to saline in conscious rabbits. Clin. Sci. 95, 693–699 (1998).

90.          Maybaum, N., Gorodetsky, E., Kalman, R. & Weinstock, M. Role of renal nerves in hemodynamic and natriuretic responses to saline in rabbits with impaired baroreflex sensitivity. Ren. Fail. 20, 219–228 (1998).

91.          Chapman, S. et al. The cognitive and neurochemical effects of the acetylcholinesterase inhibitor ENA713 on apolipoprotein E-deficient mice. Int. J. Geriatr. Psychopharmacol. 1, 171–175 (1998).

92.          Chen, Y., Shohami, E., Bass, R. & Weinstock, M. Cerebro-protective effects of ENA713, a novel acetylcholinesterase inhibitor, in closed head injury in the rat. Brain Res. 784, 18–24 (1998).

93.          Chen, Y., Shohami, E., Constantini, S. & Weinstock, M. Rivastigmine, a Brain-Selective Acetylcholinesterase Inhibitor, Ameliorates Cognitive and Motor Deficits Induced by Closed-Head Injury in the Mouse. J. Neurotrauma 15, 231–237 (1998).

94.          Chapman, S. et al. The effects of the acetylcholinesterase inhibitor ENA713 and the M1 agonist AF150(S) on apolipoprotein E deficient mice. J. Physiol. Paris 92, 299–303 (1998).

95.          Poltyrev, T. & Weinstock, M. Effect of prenatal stress on opioid component of exploration in different experimental situations. Pharmacol. Biochem. Behav. 58, 387–393 (1997).

96.          Weinstock, M. Does prenatal stress impair coping and regulation of hypothalamic- pituitary-adrenal axis? Neurosci. Biobehav. Rev. 21, 1–10 (1997).

97.          Weinstock, M. Possible role of the cholinergic system and disease models. Journal of Neural Transmission, Supplement 93–102 (1997) doi:10.1007/978-3-7091-6844-8_10.

98.          Poltyrev, T., Keshet, G. I., Kay, G. & Weinstock, M. Role of experimental conditions in determining differences in exploratory behavior of prenatally stressed rats. Dev. Psychobiol. 29, 453–462 (1996).

99.          Cohen, E., Keshet, G., Shavit, Y. & Weinstock, M. Prenatal naltrexone facilitates male sexual behavior in the rat. Pharmacol. Biochem. Behav. 54, 183–188 (1996).

100.        Weinstock, M., Gorodetsky, E. & Kalman, R. Renal denervation prevents sodium retention and hypertension in salt-sensitive rabbits with genetic baroreflex impairment. Clin. Sci. 90, 287–293 (1996).

101.        Chen, Y., Constantini, S., Trembovler, V., Weinstock, M. & Shohami, E. An experimental model of closed head injury in mice: Pathophysiology, histopathology, and cognitive deficits. J. Neurotrauma 13, 557–568 (1996).

102.        Weinstock, M. The pharmacotherapy of Alzheimer’s disease based on the cholinergic hypothesis: An update. Neurodegeneration 4, 349–356 (1995).

103.        Kaczmarczyk, G., Koch, L., Mohnhaupt, R., Vogel, T. & Weinstock, M. Cardiac baroreflex sensitivity and sodium excretion are reduced both by a deficit and an excess of dietary salt in the conscious dog. J. Lab. Clin. Med. 125, 120–126 (1995).

104.        Keshet, G. I. & Weinstock, M. Maternal naltrexone prevents morphological and behavioral alterations induced in rats by prenatal stress. Pharmacol. Biochem. Behav. 50, 413–419 (1995).

105.        Weinstock, M. & Gorodetsky, E. Comparison of the effects of Angiotensin II, losartan, and enalapril on baroreflex control of heart rate in conscious rabbits. J. Cardiovasc. Pharmacol. 25, 501–507 (1995).

106.        Keshet, G. I. & Weinstock, M. Maternal naltrexone reverses abnormalities induced by prenatal stress in rats. Regul. Pept. 53, S181–S182 (1994).

107.        Weinstock, M., Razin, M., Chorev, M. & Enz, A. Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors. J. Neural Transm. Suppl. 43, 219–225 (1994).

108.        Weinstock, M. & Borosh, M. Low baroreflex sensitivity predisposes to salt-sensitive hypertension in the rabbit. Am. J. Physiol. - Hear. Circ. Physiol. 264, H505–H511 (1993).

109.        Razin, M., Borosh, M. & Weinstock, M. Rabbits with a genetic impairment in baroreceptor reflex sensitivity show abnormal renal haemodynamics and proximal tubular sodium reabsorption in response to a saline infusion. J. Hypertens. 11, 799–804 (1993).

110.        Weinstock, M., Matlina, E., Maor, G. I., Rosen, H. & McEwen, B. S. Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat. Brain Res. 595, 195–200 (1992).

111.        Weksler-Zangen, S., Chorev, M. & Weinstock, M. Contrasting Influences of Central and Peripheral Opioids on Cardiac Baroreflex Sensitivity in Rabbits. J. Cardiovasc. Pharmacol. 20, 688–693 (1992).

112.        Elmalem, E., Chorev, M. & Weinstock, M. Antagonism of morphine-induced respiratory depression by novel anticholinesterase agents. Neuropharmacology 30, 1059–1064 (1991).

113.        Weinstock, M., Borosh, M., Kafri, O. & Kaczmarczyk, G. Relationship between baroreflex sensitivity, renin suppression and natriuresis in salt-sensitive rabbits. J. Hypertens. 9, 799–804 (1991).

114.        Weinstock, M. & Weksler‐Zangen, S. OPIOID PEPTIDES MEDIATE SYMPATHETIC INHIBITION IN RESPONSE TO BARORECEPTOR ACTIVATION IN A DISTINCT GENETIC STRAIN OF RABBIT. Clin. Exp. Pharmacol. Physiol. 16, 97–101 (1989).

115.        Fride, E. & Weinstock, M. Alterations in behavioral and striatal dopamine asymmetries induced by prenatal stress. Pharmacol. Biochem. Behav. 32, 425–430 (1989).

116.        Ben-Ishay, D. et al. Inherited resistance to salt-induced hypertension. Which mechanisms? . Nephrologie 9, 15–20 (1988).

117.        Fride, E. & Weinstock, M. Prenatal stress increase anxiety related behavior and alters cerebral lateralization of dopamine activity. Life Sci. 42, 1059–1065 (1988).

118.        Weinstock, M., Fride, E. & Hertzberg, R. Prenatal stress effects on functional development of the offspring. Progress in Brain Research vol. 73 319–331 (1988).

119.        Weinstock, M., Korner, P. I., Head, G. A. & Dorward, P. K. Differentiation of cardiac baroreflex properties by cuff and drug methods in two rabbit strains. Am. J. Physiol. - Regul. Integr. Comp. Physiol. 255, (1988).

120.        MELMED, R. N., ROTH, D., WEINSTOCK‐ROSIN, M. & EDELSTEIN, E. L. The Influence of Emotional State on the Mobilization of Marginal Pool Leukocytes after Insulin‐Induced Hypoglycemia. A Possible Role for Eicosanoids as Major Mediators of Psychosomatic Processes. Annals of the New York Academy of Sciences vol. 496 467–476 (1987).

121.        Hovav, E. & WeinstocK, M. Temporal factors influencing the development of acute tolerance to opiates. J. Pharmacol. Exp. Ther. 242, 251–256 (1987).

122.        Fride, E. & Weinstock, M. Increased interhemispheric coupling of the dopamine systems induced by prenatal stress. Brain Res. Bull. 18, 457–461 (1987).

123.        Fride, E., Soreq, H. & Weinstock, M. Are the effects of gestational stress on motor development and cerebellar cholinesterase activity mediated prenatally? Int. J. Dev. Neurosci. 4, 407–413 (1986).

124.        Benita, S., Friedman, D. & Weinstock, M. Physostigmine emulsion: a new injectable controlled release delivery system. Int. J. Pharm. 30, 47–55 (1986).

125.        Vatashsky, E., Beilin, B., Razin, M. & Weinstock, M. Mechanism of antagonism by physostigmine of acute flunitrazepam intoxication. Anesthesiology 64, 248–252 (1986).

126.        Benita, S., Friedman, D. & Weinstock, M. Pharmacological evaluation of an injectable prolonged release emulsion of physostigmine in rabbits. J. Pharm. Pharmacol. 38, 653–658 (1986).

127.        Manoach, M. et al. Factors influencing spontaneous initiation and termination of ventricular fibrillation. Jpn. Heart J. 27, 365–375 (1986).

128.        Fride, E., Dan, Y., Feldon, J., Halevy, G. & Weinstock, M. Effects of prenatal stress on vulnerability to stress in prepubertal and adult rats. Physiol. Behav. 37, 681–687 (1986).

129.        Shohami, E., Evron, S., Weinstock, M., Soffer, D. & Carmon, A. A new animal model for action myoclonus. Adv. Neurol. 43, 545–552 (1986).

130.        Weinstock, M., Blotnick, S. & Segel, M. Seasonal variation in the development of stress-induced systolic hypertension in the rat. J. Hypertens. 3, S107–S109 (1985).

131.        Beilin, B., Vatashsky, E. & Weinstock, M. Physostigmine as an antidote for poisoning by combination of thioridazine and trihexyphenidyl. Br. J. Clin. Pract. 39, 400–401 (1985).

132.        Fride, E., Dan, Y., Gavish, M. & Weinstock, M. Prenatal stress impairs maternal behavior in a conflict situation and reduces hippocampal benzodiazepine receptors. Life Sci. 36, 2103–2109 (1985).

133.        Beilin, B., Vatashsky, E., Aronson, H. B. & Weinstock, M. Naloxone reversal of postoperative apnea in a premature infant. Anesthesiology 63, 317–318 (1985).

134.        Weinstock, M. & Schorer-Apelbaum, D. Impaired baroreflex sensitivity in the aetiology of salt hypertension in the rabbit. Clin. Sci. 68, 489–493 (1985).

135.        Chrubasik, J. et al. SOMATOSTATIN, A POTENT ANALGESIC. Lancet 324, 1208–1209 (1984).

136.        Amitzur, G., Manoach, M. & Weinstock, M. The influence of cardiac cholinergic activation on the induction and maintenace of ventricular fibrillation. Basic Res. Cardiol. 79, 690–697 (1984).

137.        Vatashsky, E., Beilin, B., Aronson, H. B. & Weinstock, M. Oral flunitrazepam in the prevention of local anaesthetic-induced convulsions in mice. Can. Anaesth. Soc. J. 31, 646–649 (1984).

138.        Weinstock, M., Schorer-Apelbaum, D. & Ben-Ishay, D. Baroreflex sensitivity and susceptibility to systolic hypertension induced by DOCA-salt in the Sabra rat. Am. J. Physiol. - Hear. Circ. Physiol. 15, H448–H452 (1984).

139.        Freide, E. & Weinstock, M. The effects of prenatal exposure to predictable or unpredictable stress on early development in the rat. Dev. Psychobiol. 17, 651–660 (1984).

140.        Weinstock, M., Schorer-Apelbaum, D. & Rosin, A. J. Endogenous opiates mediate cardiac sympathetic inhibition in response to a pressor stimulus in rabbits. J. Hypertens. 2, 639–646 (1984).

141.        Weinstock, M. & Rosin, A. J. RELATIVE CONTRIBUTIONS OF VAGAL AND CARDIAC SYMPATHETIC NERVES TO THE REFLEX BRADYCARDIA INDUCED BY A PRESSOR STIMULUS IN THE CONSCIOUS RABBIT: COMPARISON OF ‘STEADY STATE’ AND ‘RAMP’ METHODS. Clin. Exp. Pharmacol. Physiol. 11, 133–141 (1984).

142.        Schorer-Apelbaum, D., Weinstock, M. & Ben-Lshay, D. Sympathetic component of baroreflex control of heart rate is impaired in hypertension-prone (SBH) sabra rats. J. Hypertens. 2, 257–260 (1984).

143.        Weinstock, M. MEPTAZINOL. Lancet 322, 1027 (1983).

144.        Blum, B. et al. A pharmacological analysis of autonomic pathways mediating myocardial disturbances originating in a lateral hypothalamic area of the cat. Eur. J. Pharmacol. 88, 301–310 (1983).

145.        Segal, M. & Weinstock, M. Differential effects of 5-hydroxytryptamine antagonists on behaviors resulting from activation of different pathways arising from the raphe nuclei. Psychopharmacology (Berl). 79, 72–78 (1983).

146.        Weinstock, M. & Mccarty, R. Vasodilator Responses to Cholinergic and Adrenergic Stimulants in Spontaneously Hypertensive (SHR) and Wistar-Kyoto (WKY) Normotensive Rats. Proc. Soc. Exp. Biol. Med. 172, 194–201 (1983).

147.        Snir Mor, I., Weinstock, M., Davidson, J. T. & Bahar, M. Physostigmine antagonizes morphine-induced respiratory depression in human subjects. Anesthesiology 59, 6–9 (1983).

148.        Weinstock, M., Dalith, M. & Shohami, E. Hypersensitivity of morphine-tolerant rabbits to the respiratory stimulant effect of a cholinergic agonist. J. Pharmacol. Exp. Ther. 226, 232–237 (1983).

149.        Bai, T. R. et al. Sudden-Infant-Death Syndrome. N. Engl. J. Med. 307, 891–893 (1982).

150.        Weinstock, M., Davidson, J. T., Rosin, A. J. & Schnieden, H. Effect of physostigmine on morphine-induced postoperative pain and somnolence. Br. J. Anaesth. 54, 429–434 (1982).

151.        WEINSTOCK, M. ACTIVATION OF CENTRAL MUSCARINIC RECEPTORS CAUSES RESPIRATORY STIMULATION IN CONSCIOUS ANIMALS. Br. J. Pharmacol. 74, 587–592 (1981).

152.        Weinstock, M., Erez, E. & Roll, D. Antagonism of the cardiovascular and respiratory depressant effects of morphine in the conscious rabbit by physostigmine. J. Pharmacol. Exp. Ther. 218, 504–508 (1981).

153.        Weinstock, M., Roll, D. & Zilberman, Y. AN ANALYSIS OF THE RESPIRATORY STIMULANT EFFECT OF PHYSOSTIGMINE AND NEOSTIGMINE DM THE CONSCIOUS RABBIT. Clin. Exp. Pharmacol. Physiol. 8, 151–158 (1981).

154.        Weinstock, M. et al. Evidence that noradrenaline modulates the increase in striatal dopamine metabolism induced by muscarinic receptor stimulation. Eur. J. Pharmacol. 68, 427–435 (1980).

155.        Weinstock, M., Zavadil 3rd., A. P. & Kopin, I. J. Peripheral catecholamines mediate certain responses to central cholinergic receptor stimulation by oxotremorine. Monogr. Neural Sci. 7, 138–145 (1980).

156.        Manoach, M., Netz, H., Erez, M. & Weinstock, M. Ventricular self-defibrillation in mammals: Age and drug dependence. Age Ageing 9, 112–116 (1980).

157.        Weinstock, M., Roll, D., Erez, E. & Bahar, M. Physostigmine antagonizes morphine-induced respiratory depression but not analgesia in dogs and rabbits. Br. J. Anaesth. 52, 1171–1176 (1980).

158.        Weinstock, M. & Weiss, C. Antagonism by propranolol of isolation-induced aggression in mice: Correlation with 5-hydroxytryptamine receptor blockade. Neuropharmacology 19, 653–656 (1980).

159.        Manoach, M., Aygen, M. & Weinstock, M. Influence of drugs on transient and sustained ventricular fibrillation in different species. Isr. J. Med. Sci. 16, 224 (1980).

160.        Weinstock, M., Zavadil III, A. P. & Kopin, I. J. Differential effects of d- and l-propranolol on dopamine turnover stimulated by oxotremorine in striatal and mesolimbic areas of rat brain. Eur. J. Pharmacol. 59, 187–193 (1979).

161.        Weinstock, M., Zavadil III, A. P., Chiueh, C. C. & Kopin, I. J. The effect of oxotremorine on blood pressure and plasma catecholamines in conscious and anesthetized rats. Life Sci. 24, 301–309 (1979).

162.        WEINSTOCK, M. & WEISS, C. EFFECTS OF PROCAINE AND EXTRACELLULAR CALCIUM CONCENTRATION ON RESPONSE OF RAT STOMACH FUNDUS MUSCLE TO ACETYLCHOLINE AND 5‐HYDROXYTRYPTAMINE. Br. J. Pharmacol. 65, 593–599 (1979).

163.        Weinstock, M., Zavadil, A. P., Rosin, A. J., Chiueh, C. C. & Kopin, I. J. The role of peripheral catecholamines in oxotremorine tremor in the rat and its antagonism by beta adrenoceptor blocking agents. J. Pharmacol. Exp. Ther. 206, 91–96 (1978).

164.        Weinstock, M., Thoa, N. B. & Kopin, I. J. β-Adrenoceptors modulate noradrenaline release from axonal sprouts in cultured rat superior cervical ganglia. Eur. J. Pharmacol. 47, 297–302 (1978).

165.        Zatz, M. & Weinstock, M. Electric field stimulation releases norepinephrine and cyclic GMP from the rat pineal gland. Life Sci. 22, 767–772 (1978).

166.        Erez, M., Shtacher, G. & Weinstock, M. Cardioselectivity as a Function of Molecular Structure in β-Adrenoceptor Blocking Agents of the 1-(Para-substituted aryloxy)-3-(isopropylamino)propan-2-ol Type. J. Med. Chem. 21, 982–984 (1978).

167.        Weinstock, M., Speiser, Z. & Ashkenazi, R. Changes in brain catecholamine turnover and receptor sensitivity induced by social deprivation in rats. Psychopharmacology (Berl). 56, 205–209 (1978).

168.        Shoham-Moshonov, S. R. & Weinstock, M. Nature of seasonal variation in development of acute tolerance to morphine. Eur. J. Pharmacol. 43, 153–161 (1977).

169.        Weinstock, M., Shoham-Moshonov, S., Teitelbaum, D. & Arnon, R. Inactivation of neurogenic 5-hydroxytryptamine receptors in guinea pigs with experimental allergic encephalomyelitis (EAE) induced paralysis. Brain Res. 125, 192–195 (1977).

170.        Fisher, A., Weinstock, M., Eliash, S., Gitter, S. & Cohen, S. Prevention by drugs of tachyphylaxis at nicotinic receptors in the cat superior cervical ganglion in situ. Eur. J. Pharmacol. 42, 11–20 (1977).

171.        Weinstock, M., Weiss, C. & Gitter, S. Blockade of 5-hydroxytryptamine receptors in the central nervous system by β-adrenoceptor antagonists. Neuropharmacology 16, 273–276 (1977).

172.        Weinstock, M., Zavadil, A. P. & Rosin, A. J. Peripheral catecholamines released by oxotremorine modulate tremor in the rat. Pharmacologist 19, (1977).

173.        Blum, B., Weinstock, M. & Davidovich, Z. A. Effect of β-adrenoceptor antagonists on centrally induced changes in ECG and blood pressure. Fed. Proc. 36, (1977).

174.        Weinstock, M. The presynaptic effect of β-adrenoceptor antagonists on noradrenergic neurones. Life Sci. 19, 1453–1466 (1976).

175.        Fisher, A., Grunfeld, Y., Weinstock, M., Gitter, S. & Cohen, S. A study of muscarinic receptor heterogeneity with weak antagonists. Eur. J. Pharmacol. 38, 131–139 (1976).

176.        Weinstock, M. & Cohen, D. Tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia. Eur. J. Pharmacol. 40, 321–328 (1976).

177.        Fisher, A., Weinstock, M., Gitter, S. & Cohen, S. A new probe for heterogeneity in muscarinic receptors: 2-methyl-spiro-(1,3-dioxolane-4,3′)-quinuclidine. Eur. J. Pharmacol. 37, 329–338 (1976).

178.        Speiser, Z. & Weinstock, M. Reduction by propranolol of raised urinary output of MHPG in hyperactive rats. Pharmacol. Biochem. Behav. 4, 531–534 (1976).

179.        Weiss, C. & Weinstock, M. Interaction of β adrenoceptor antagonists, 5 hydroxytryptamine and calcium ions in rat stomach smooth muscle. Isr. J. Med. Sci. 12, 1517 (1976).

180.        Weinstock, M. & Shoham Moshonov, S. Seasonal variation in development of tolerance to morphine. Isr. J. Med. Sci. 12, 1521 (1976).

181.        Cohen, D. & Weinstock, M. Evidence in favor of an anticholinergic mechanism of action of tricyclic antidepressant drugs. Isr. J. Med. Sci. 12, 1516–1517 (1976).

182.        Ashkenazi, R. & Weinstock, M. Behavioral effects of paramethoxyphenylethylamine: a pharmacological study. Isr. J. Med. Sci. 12, 1518 (1976).

183.        Erez, M., Weinstock, M., Cohen, S. & Shtacher, G. Potential probe for isolation of the β-adrenoceptor, chloropractolol. Nature 255, 635–636 (1975).

184.        Weinstock, M. & Schechter Harari, Y. Effect of D and L propranolol on ganglion stimulation by 5 hydroxytryptamine and dimethyl phenyl piperizinium in the cat. Isr. J. Med. Sci. 11, 863–864 (1975).

185.        Fisher, A., Weinstock, M. & Cohen, S. Action of specific new rigid agonists and antagonists on muscarinic receptors. Isr. J. Med. Sci. 11, 861 (1975).

186.        Weinstock, M. & Schechter, Y. Antagonism by propranolol of the ganglion stimulant action of 5-hydroxytryptamine. Eur. J. Pharmacol. 32, 293–301 (1975).

187.        Weinstock, M. & Shoham, S. Seasonal variation in sensitivity of guinea pig tissues to agonists. Nature 251, 427–428 (1974).

188.        SCHECHTER, Y. & WEINSTOCK, M. β‐ADRENOCEPTOR BLOCKING AGENTS AND RESPONSES TO ADRENALINE AND 5‐HYDROXYTRYPTAMINE IN RAT ISOLATED STOMACH AND UTERUS. Br. J. Pharmacol. 52, 283–287 (1974).

189.        SPEISER, Z. & WEINSTOCK, M. SUPERSENSITIVITY TO ISOPRENALINE INDUCED IN RATS BY PROLONGED ISOLATION. Br. J. Pharmacol. 52, 605–608 (1974).

190.        Weinstock, M., Schechter, Y., Erez, M. & Shtacher, G. Changes in β-adrenoceptor-blocking activity produced by chemical modifications in the practolol molecule. Eur. J. Pharmacol. 26, 191–197 (1974).

191.        SHOHAM, S. & WEINSTOCK, M. THE ROLE OF SUPERSENSITIVITY TO ACETYLCHOLINE IN THE PRODUCTION OF TOLERANCE TO MORPHINE IN STIMULATED GUINEA‐PIG ILEUM. Br. J. Pharmacol. 52, 597–603 (1974).

192.        Weinstock, M. & Speiser, Z. Modification by propranolol and related compounds of motor activity and stereotype behaviour induced in the rat by amphetamine. Eur. J. Pharmacol. 25, 29–35 (1974).

193.        Speizer, Z. & Weinstock, M. The influence of propranolol on abnormal behavior induced in rats by prolonged isolation: an animal model for mania? BRIT.J.PHARMACOL. 48, 348P-349P (1973).

194.        Weinstock, M. & Speiser, Z. The effect of dl-propranolol, d-propranolol and practolol on the hyperactivity induced in rats by prolonged isolation. Psychopharmacologia 30, 241–250 (1973).

195.        ELIASH, S. & WEINSTOCK, M. Factors influencing the adrenergic neurone blocking action of propranolol. Br. J. Pharmacol. 45, 630–634 (1972).

196.        Marshall, I. & Weinstock, M. Quantitative method for assessing one symptom of the withdrawal syndrome in mice after chronic morphine administration [12]. Nature 234, 223–224 (1971).

197.        ELIASH, S. & WEINSTOCK, M. Role of adrenergic neurone blockade in the hypotensive action of propranolol. Br. J. Pharmacol. 43, 287–294 (1971).

198.        Starr, M. S. & Weinstock, M. Relationship between blocking antibody titres and symptomatic relief in hay-fever subjects treated with allpyral. Int. Arch. Allergy Appl. Immunol. 41, 157–159 (1971).

199.        Starr, M. S. & Weinstock, M. Studies in pollen allergy. 3. The relationship between blocking antibody levels and symptomatic relief following hyposensitisation with allpyral in hay fever subjects. Int. Arch. Allergy Appl. Immunol. 38, 514–521 (1970).

200.        Weinstock, M. & Starr, M. S. Studies in pollen allergy. II. Comparison of leucocyte sensitivity and levels of blocking antibody in hay fever subjects administered allpyral or pollaccine. Int. Arch. Allergy Appl. Immunol. 37, 385–392 (1970).

201.        Starr, M. S. & Weinstock, M. Studies in pollen allergy: I. A method for estimating histamine release from sensitised leucocytes in the presence of serum. Int. Arch. Allergy Immunol. 37, 239–247 (1970).

202.        Weinstock, M. & Marshall, A. S. Factors influencing the incidence of reversible lens opacities in solitary and aggregated mice. J. Pharmacol. Exp. Ther. 170, 168–172 (1969).

203.        Marshall, I. & Weinstock, M. A quantitative method for the assessment of physical dependence on narcotic analgesics in mice. Br. J. Pharmacol. 37, 505P-506P (1969).

204.        Weinstock, M. & Marshall, A. S. The influence of the sympathetic nervous system on the action of drugs on the lens. J. Pharmacol. Exp. Ther. 166, 8–13 (1969).

205.        Weinstock, M. The role of the sympathetic nervous system in mediating the action of analgesic drugs on the lens. Naunyn. Schmiedebergs. Arch. Pharmakol. Exp. Pathol. 259, 201–202 (1968).

206.        Weinstock, M. & Scott, J. D. Effect of various agents on drug-induced opacities of the lens. Exp. Eye Res. 6, 368-370,IN13,371-375 (1967).

207.        COX, B. M. & WEINSTOCK, M. THE EFFECT OF ANALGESIC DRUGS ON THE RELEASE OF ACETYLCHOLINE FROM ELECTRICALLY STIMULATED GUINEA‐PIG ILEUM. Br. J. Pharmacol. Chemother. 27, 81–92 (1966).

208.        COX, B. M. & WEINSTOCK, M. QUANTITATIVE STUDIES OF THE ANTAGONISM BY NALORPHINE OF SOME OF THE ACTIONS OF MORPHINE‐LIKE ANALGESIC DRUGS. Br. J. Pharmacol. Chemother. 22, 289–300 (1964).

209.        Weinstock, M., Stewart, H. C. & Butterworth, K. R. The action of drugs on the formation of transient lens opacities. Exp. Eye Res. 2, 28–32 (1963).

210.        WEINSTOCK, M. SIMILARITY BETWEEN RECEPTORS RESPONSIBLE FOR THE PRODUCTION OF ANALGESIA AND LENTICULAR OPACITY. Br. J. Pharmacol. Chemother. 17, 433–441 (1961).

211.        Weinstock, M. & Stewart, H. C. OCCURRENCE IN RODENTS OF REVERSIBLE DRUG-INDUCED OPACITIES OF THE LENS. Br. J. Ophthalmol. 45, 408–414 (1961).

212.        Weinstock, M., Stewart, H. C. & Butterworth, K. R. Lenticular effect in mice of some morphine-like drugs. Nature 182, 1519–1520 (1958).