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School of Pharmacy : Domb Avi

Researchers

 Last updated Septmber 2023 - School of Pharmacy

List of Publications

1.            Shapira-Furman, T., Bar-Hai, A., Hoffman, A. & Domb, A. J. The Synthesis of SNAC Phenolate Salts and the Effect on Oral Bioavailability of Semaglutide. Molecules 29, (2024).

2.            Mandal, M. K. & Domb, A. J. Antimicrobial Activities of Natural Bioactive Polyphenols. Pharmaceutics 16, (2024).

3.            Avraham, Y. et al. Sustained insulin treatment restoring metabolic status, body weight, and cognition in an anorexia nervosa-like animal model in mice. Behav. Brain Res. 466, (2024).

4.            Shapira-Furman, T. & Domb, A. J. Insulin Extended Release from PLA-PEG Stereocomplex Nanoparticles. Macromol. Biosci. 24, (2024).

5.            Saklani, R. & Domb, A. J. Peptide and Protein Stereocomplexes. ACS Omega 9, 17726–17740 (2024).

6.            Levinson, J., Buchnik, E., Ariel, B. & Domb, A. J. Scientific evidence in courts of law: An overview. in Judicial Independence: Cornerstone of Democracy 140–163 (Brill, 2024). doi:10.1163/9789004535091_012.

7.            Shapira-Furman, T., Nyska, A. & Domb, A. J. Biocompatibility of insulin-PLA stereocomplex. J. Bioact. Compat. Polym. (2024) doi:10.1177/08839115241241047.

8.            Kumar, A., Lamberti, Y., Lewis, R. Y., Marco, E. & Domb, A. J. Analysis of fabrics obtained during the archeological excavation sites in Israel. Polym. Adv. Technol. 35, (2024).

9.            Kumar, A. et al. A method for cleaning of used disposable plastic parts from automated RNA extraction system. Polym. Adv. Technol. 35, (2024).

10.          Ramot, Y. et al. Assessment of Bioprotect’s Biodegradable Balloon System as a Rectal Spacer in Radiotherapy: An Animal Study on Tissue Response and Biocompatibility. Pharmaceutics 15, (2023).

11.          Guruprasad Reddy, P., Bar-Hai, A., Hoffman, A., Marc Feldmann, S. & Domb, A. J. Novel phenolate salts of bioactive agents: Cannabidiol phenolate salts. Bioorg. Chem. 141, (2023).

12.          Abdel-Haq, M. et al. Effects of extended-release 7-nitroindazole gel formulation treatment on the behavior of Shank3 mouse model of autism. Nitric Oxide - Biol. Chem. 140–141, 41–49 (2023).

13.          Abtew, E. & Domb, A. J. Synthesis of Polypeptides and Poly(α-hydroxy esters) from Aldehydes Using Strecker Synthesis. ACS Omega 8, 40407–40416 (2023).

14.          Buchnik, E., Ariel, B., Domb, A., Treves, N. & Gafny, R. The role of DNA in criminal indictments in Israel. J. Forensic Sci. 68, 1755–1758 (2023).

15.          AbdEl-haq, M. et al. Paclitaxel Delivery to the Brain for Glioblastoma Treatment. Int. J. Mol. Sci. 24, (2023).

16.          Ramot, Y. et al. Preclinical In-Vivo Safety of a Novel Thyrotropin-Releasing Hormone-Loaded Biodegradable Nanoparticles After Intranasal Administration in Rats and Primates. Int. J. Toxicol. 42, 334–344 (2023).

17.          Reddy, P. G. & Domb, A. J. Bioactive Phenolate Salts: Thymol Salts. ChemMedChem 18, (2023).

18.          Guruprasad Reddy, P., Hu, T., Reches, M. & Domb, A. J. Antimicrobial dichloroisocyanurate-salts for controlled release of chlorine. Org. Biomol. Chem. 21, 5440–5450 (2023).

19.          Yuce-Erarslan, E., Domb, A. J., Kasem, H., Uversky, V. N. & Coskuner-Weber, O. Intrinsically Disordered Synthetic Polymers in Biomedical Applications. Polymers (Basel). 15, (2023).

20.          Nam-Cha, S. H. et al. Methacrylate Cationic Nanoparticles Activity against Different Gram-Positive Bacteria. Antibiotics 12, (2023).

21.          Hosseinkhani, H., Domb, A. J., Sharifzadeh, G. & Nahum, V. Gene Therapy for Regenerative Medicine. Pharmaceutics 15, (2023).

22.          Klein, E. et al. A Novel Platform for Root Protection Applies New Root-Coating Technologies to Mitigate Soil-Borne Tomato Brown Rugose Fruit Virus Disease. Viruses 15, (2023).

23.          Kommineni, N. et al. SNAC for Enhanced Oral Bioavailability: An Updated Review. Pharm. Res. 40, 633–650 (2023).

24.          Reddy, P. G. & Domb, A. J. Polyanhydride Chemistry. Biomacromolecules 23, 4959–4984 (2022).

25.          Ghosh, R., Siman, P. & Domb, A. J. Poly(ester-anhydrides) with controlled molecular weight and structure. Polym. Adv. Technol. 33, 3774–3781 (2022).

26.          Haim Zada, M., Rottenberg, Y. & Domb, A. J. Peptide loaded polymeric nanoparticles by non-aqueous nanoprecipitation. J. Colloid Interface Sci. 622, 904–913 (2022).

27.          Arun, Y., Ghosh, R. & Domb, A. J. Poly(ester-anhydrides) Derived from Esters of Hydroxy Acid and Cyclic Anhydrides. Biomacromolecules 23, 3417–3428 (2022).

28.          Ghosh, R., Arun, Y., Siman, P. & Domb, A. J. Synthesis of Aliphatic Polyanhydrides with Controllable and Reproducible Molecular Weight. Pharmaceutics 14, (2022).

29.          Nahum, V. & Domb, A. J. Solid lipid microspheres decorated nanoparticles as drug carriers. Int. J. Pharm. 621, (2022).

30.          Feng, Y., He, B., Li, W. & Domb, A. J. Editorial: Multifunctional Polymeric Materials for Drug and Gene Delivery. Front. Bioeng. Biotechnol. 10, (2022).

31.          Ben-David, E. et al. Characterization and Evaluation of Injectable Biodegradable Polymer Multimodality Radiologic Markers in an In Vivo Murine Model. Biomacromolecules 23, 1672–1679 (2022).

32.          Bar-Hai, A., Domb, A. J. & Hoffman, A. Strategies for enhancing the oral bioavailability of cannabinoids. Expert Opin. Drug Metab. Toxicol. 18, 313–322 (2022).

33.          Serra, R. et al. Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model. Eur. J. Pharm. Biopharm. 170, 179–186 (2022).

34.          Steinman, N. Y. & Domb, A. J. Instantaneous degelling thermoresponsive hydrogel. Gels 7, (2021).

35.          Steinman, N. Y., Hu, T., Dombrovsky, A., Reches, M. & Domb, A. J. Antiviral Polymers Based on N-Halamine Polyurea. Biomacromolecules 22, 4357–4364 (2021).

36.          Domb, A. J., Sharifzadeh, G., Nahum, V. & Hosseinkhani, H. Safety evaluation of nanotechnology products. Pharmaceutics 13, (2021).

37.          Guruprasad Reddy, P. & Domb, A. J. Formation of micro/nanoparticles and microspheres from polyesters by dispersion ring-opening polymerization. Polym. Adv. Technol. 32, 3835–3856 (2021).

38.          Tekale, S. U., Rottenberg, Y., Ingle, R. D., Domb, A. J. & Pawar, R. P. Recent developments in biodegradable block copolymers. Polym. Adv. Technol. 32, 3877–3899 (2021).

39.          Kumar, A. & Domb, A. J. Polymerization Enhancers for Cyanoacrylate Skin Adhesive. Macromol. Biosci. 21, (2021).

40.          Arun, Y., Ghosh, R. & Domb, A. J. Biodegradable Hydrophobic Injectable Polymers for Drug Delivery and Regenerative Medicine. Adv. Funct. Mater. 31, (2021).

41.          Klein, H. et al. Covalent immobilization of polyaniline doped with ag+ or cu2+ on carbon nanotubes for ethylene chemical sensing. Nanomaterials 11, (2021).

42.          Itin, C., Domb, A. J. & Hoffman, A. On the Suitability of Porcine Labial Mucosa as a Model for Buccal Mucosal Drug Delivery Research. J. Pharm. Sci. 110, 1863–1864 (2021).

43.          Itin, C., Komargodski, R., Barasch, D., Domb, A. J. & Hoffman, A. Prolonged Delivery of Apomorphine Through the Buccal Mucosa, Towards a Noninvasive Sustained Administration Method in Parkinson’s Disease: In Vivo Investigations in Pigs. J. Pharm. Sci. 110, 1824–1833 (2021).

44.          Gore, V. A. et al. Synthesis and Biological Evaluation of Novel Thiazole Hydrazines as Antimicrobial and Antimalarial Agents. Lett. Appl. NanoBioScience 10, 1846–1855 (2021).

45.          Rakedzon, S., Neuberger, A., Domb, A. J., Petersiel, N. & Schwartz, E. From hydroxychloroquine to ivermectin: what are the anti-viral properties of anti-parasitic drugs to combat SARS-CoV-2? J. Travel Med. 28, (2021).

46.          Nahum, V. & Domb, A. J. Recent developments in solid lipid microparticles for food ingredients delivery. Foods 10, 1–25 (2021).

47.          Arun, Y., Daifa, M. & Domb, A. J. Polyhydroxamic acid as an efficient metal chelator and flocculant for wastewater treatment. Polym. Adv. Technol. 32, 842–852 (2021).

48.          Duo, X. et al. Erratum to: Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating and nuclear accumulation (Frontiers of Chemical Science and Engineering, (2020), 14, 5, (889-901), 10.1007/s11705-020-1919-8). Front. Chem. Sci. Eng. 15, 220 (2021).

49.          Ramot, Y. et al. Treatment of contaminated radial fracture in sprague-dawley rats by application of a degradable polymer releasing gentamicin. J. Toxicol. Pathol. 34, 11–22 (2021).

50.          Basu, A. & Domb, A. J. Ion Exchange Nanoparticles for Ophthalmic Drug Delivery. Bioconjug. Chem. 31, 2726–2736 (2020).

51.          Haim Zada, M., Gallimidi, Z., Schlesinger-Laufer, M., Nyska, A. & Domb, A. J. Biodegradable Breast Tissue Marker Clip. ACS Appl. Bio Mater. 3, 7439–7453 (2020).

52.          Steinman, N. Y., Bentolila, N. Y. & Domb, A. J. Effect of molecular weight on gelling and viscoelastic properties of poly(Caprolactone)–b‐ poly(ethylene glycol)–b‐poly(caprolactone) (PCL– PEG–PCL) hydrogels. Polymers (Basel). 12, 1–12 (2020).

53.          Duo, X. et al. Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating and nuclear accumulation. Front. Chem. Sci. Eng. 14, 889–901 (2020).

54.          Belay, C. et al. Asymmetric trisalkylamine cyclopropenium derivatives with antimicrobial activity. Bioorg. Chem. 102, (2020).

55.          Izgelov, D. et al. Pharmacokinetic investigation of synthetic cannabidiol oral formulations in healthy volunteers. Eur. J. Pharm. Biopharm. 154, 108–115 (2020).

56.          Itin, C., Komargodski, R., Domb, A. J. & Hoffman, A. Controlled Delivery of Apomorphine Through Buccal Mucosa, Towards a Noninvasive Administration Method in Parkinson’s Disease: A Preclinical Mechanistic Study. J. Pharm. Sci. 109, 2729–2734 (2020).

57.          Steinman, N. Y., Campos, L. M., Feng, Y., Domb, A. J. & Hosseinkhani, H. Cyclopropenium nanoparticles and gene transfection in cells. Pharmaceutics 12, 1–12 (2020).

58.          Golenser, J. et al. Treatment of Experimental Cerebral Malaria by Slow Release of Artemisone From Injectable Pasty Formulation. Front. Pharmacol. 11, (2020).

59.          Izgelov, D., Regev, A., Domb, A. J. & Hoffman, A. Using the Absorption Cocktail Approach to Assess Differential Absorption Kinetics of Cannabidiol Administered in Lipid-Based Vehicles in Rats. Mol. Pharm. 17, 1979–1986 (2020).

60.          Kommineni, N., Pandi, P., Chella, N., Domb, A. J. & Khan, W. Antibody drug conjugates: Development, characterization, and regulatory considerations. Polym. Adv. Technol. 31, 1177–1193 (2020).

61.          Izgelov, D., Domb, A. J. & Hoffman, A. The effect of piperine on oral absorption of cannabidiol following acute vs. chronic administration. Eur. J. Pharm. Sci. 148, (2020).

62.          Itin, C., Barasch, D., Domb, A. J. & Hoffman, A. Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol. Int. J. Pharm. 581, (2020).

63.          Izgelov, D., Shmoeli, E., Domb, A. J. & Hoffman, A. The effect of medium chain and long chain triglycerides incorporated in self-nano emulsifying drug delivery systems on oral absorption of cannabinoids in rats. Int. J. Pharm. 580, (2020).

64.          Haim Zada, M. et al. In vitro and in vivo degradation behavior and the long-term performance of biodegradable PLCL balloon implants. Int. J. Pharm. 574, (2020).

65.          Manoukian, O. S. et al. Functional polymeric nerve guidance conduits and drug delivery strategies for peripheral nerve repair and regeneration. J. Control. Release 317, 78–95 (2020).

66.          Doppalapudi, S., Jain, A., Khan, W. & Domb, A. J. Fenoldopam mesylate for treating psoriasis: A new indication for an old drug. Int. J. Pharm. 573, (2020).

67.          Domb, A. A. J. Foreword. Artif. Protein Pept. Nanofibers Des. Fabr. Charact. Appl. xix (2020) doi:10.1016/B978-0-08-102850-6.09998-8.

68.          Madhumanchi, S., Srichana, T. & Domb, A. J. Polymeric Biomaterials. in Biomedical Materials: Second Edition 49–100 (Springer International Publishing, 2020). doi:10.1007/978-3-030-49206-9_2.

69.          Sarda, S. R., Tekale, S. U., Kótai, L., Domb, A. J. & Pawar, R. P. COVID-19: A global pandemic. Eur. Chem. Bull. 9, 266–272 (2020).

70.          Haim Zada, M., Kumar, A., Elmalak, O., Mechrez, G. & Domb, A. J. Effect of Ethylene Oxide and Gamma (γ-) Sterilization on the Properties of a PLCL Polymer Material in Balloon Implants. ACS Omega 4, 21319–21326 (2019).

71.          Haim Zada, M. et al. Biodegradable implantable balloons: Mechanical stability under physiological conditions. J. Mech. Behav. Biomed. Mater. 100, (2019).

72.          Zada, M. H., Goldberg, S. N., Nissenbaum, Y., Domb, A. J. & Ben-David, E. Injectable Biodegradable Multimodal Mammography Marker. ACS Appl. Bio Mater. 2, 5069–5076 (2019).

73.          Keren, A. et al. Instantaneous depolarization of T cells via dopamine receptors, and inhibition of activated T cells of Psoriasis patients and inflamed human skin, by D1-like receptor agonist: Fenoldopam. Immunology 158, 171–193 (2019).

74.          Itin, C., Domb, A. J. & Hoffman, A. A meta-opinion: cannabinoids delivered to oral mucosa by a spray for systemic absorption are rather ingested into gastro-intestinal tract: the influences of fed / fasting states. Expert Opin. Drug Deliv. 16, 1031–1035 (2019).

75.          Daifa, M., Shmoeli, E. & Domb, A. J. Enhanced flocculation activity of polyacrylamide-based flocculant for purification of industrial wastewater. Polym. Adv. Technol. 30, 2636–2646 (2019).

76.          Kompella, U. B. et al. ISOPT Clinical Hot Topic Panel Discussion on Ocular Drug Delivery. J. Ocul. Pharmacol. Ther. 35, 457–465 (2019).

77.          SreeHarsha, N. et al. Paclitaxel loaded poly (DL lactic acid co castor oil) 60:40 with poloxamer-F68 rod shape cylindrical nanoparticle preparation and in vitro cytotoxicity studies. Polym. Adv. Technol. 30, 2613–2622 (2019).

78.          Domb, A. Functional polymers for human health. Polym. Adv. Technol. 30, 2492 (2019).

79.          Hosseinkhani, H. & Domb, A. J. Biodegradable polymers in gene-silencing technology. Polym. Adv. Technol. 30, 2647–2655 (2019).

80.          Abtew, E., Ezra, A. F., Basu, A. & Domb, A. J. Biodegradable Poly(Acetonide Gluconic Acid) for Controlled Drug Delivery. Biomacromolecules 20, 2934–2941 (2019).

81.          Kasem, H. et al. Rubber plunger surface texturing for friction reduction in medical syringes. Friction 7, 351–358 (2019).

82.          Steinman, N. Y. et al. Cyclopropenium-Based Biodegradable Polymers. Macromolecules 52, 3543–3550 (2019).

83.          Kommineni, N., Mahira, S., Domb, A. J. & Khan, W. Cabazitaxel-loaded nanocarriers for cancer therapy with reduced side effects. Pharmaceutics 11, 1–22 (2019).

84.          Zada, M. H., Kubek, M., Khan, W., Kumar, A. & Domb, A. Dispersible hydrolytically sensitive nanoparticles for nasal delivery of thyrotropin releasing hormone (TRH). J. Control. Release 295, 278–289 (2019).

85.          Shapira-Furman, T. et al. Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer. J. Control. Release 295, 93–101 (2019).

86.          Rathi, S., Saka, R., Domb, A. J. & Khan, W. Protein-based bioadhesives and bioglues. Polym. Adv. Technol. 30, 217–234 (2019).

87.          Steinman, N. Y. & Domb, A. J. Injectable pasty biodegradable polyesters derived from castor oil and hydroxyl-acid lactones. J. Pharmacol. Exp. Ther. 370, 736–741 (2019).

88.          Bulbake, U., Singh, A., Domb, A. J. & Khan, W. Therapeutic macromolecular iron chelators. Curr. Med. Chem. 26, 323–334 (2019).

89.          Steinman, N. Y. et al. Effect of PLGA block molecular weight on gelling temperature of PLGA-PEG-PLGA thermoresponsive copolymers. J. Polym. Sci. Part A Polym. Chem. 57, 35–39 (2019).

90.          Khan, W., Abtew, E., Modani, S. & Domb, A. J. Polysaccharide Based Nanoparticles. Isr. J. Chem. 58, 1315–1329 (2018).

91.          Brucks, S. D., Steinman, N. Y., Starr, R. L., Domb, A. J. & Campos, L. M. Crosslinked colloids with cyclopropenium cations. J. Polym. Sci. Part A Polym. Chem. 56, 2641–2645 (2018).

92.          Basu, A. & Domb, A. J. Recent Advances in Polyanhydride Based Biomaterials. Adv. Mater. 30, (2018).

93.          Abedini, F., Ebrahimi, M., Roozbehani, A. H., Domb, A. J. & Hosseinkhani, H. Overview on natural hydrophilic polysaccharide polymers in drug delivery. Polym. Adv. Technol. 29, 2564–2573 (2018).

94.          Kommineni, N., Saka, R., Khan, W. & Domb, A. J. Non-polymer drug-eluting coronary stents. Drug Deliv. Transl. Res. 8, 903–917 (2018).

95.          Popilski, H., Abtew, E., Schwendeman, S., Domb, A. & Stepensky, D. Efficacy of paclitaxel/dexamethasone intra-tumoral delivery in treating orthotopic mouse breast cancer. J. Control. Release 279, 1–7 (2018).

96.          Atsmon, J. et al. PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers. J. Pharm. Sci. 107, 1423–1429 (2018).

97.          Izgelov, D., Cherniakov, I., Aldouby Bier, G., Domb, A. J. & Hoffman, A. The Effect of Piperine Pro-Nano Lipospheres on Direct Intestinal Phase II Metabolism: The Raloxifene Paradigm of Enhanced Oral Bioavailability. Mol. Pharm. 15, 1548–1555 (2018).

98.          Farah, S. & Domb, A. J. Crystalline paclitaxel coated DES with bioactive protective layer development. J. Control. Release 271, 107–117 (2018).

99.          Shadmon, H., Basu, A., Eckhard, L. H., Domb, A. J. & Beyth, N. Synthesis, characterization and antibacterial activity of heterocyclic quaternary ammonium polymers. New J. Chem. 42, 15427–15435 (2018).

100.        Beyth, N., Yudovin-Farber, I., Basu, A., Weiss, E. I. & Domb, A. J. Antimicrobial nanoparticles in restorative composites. in Emerging Nanotechnologies in Dentistry: Second Edition 41–58 (Elsevier, 2018). doi:10.1016/B978-0-12-812291-4.00003-0.

101.        Cherniakov, I. et al. Piperine-pro-nanolipospheres as a novel oral delivery system of cannabinoids: Pharmacokinetic evaluation in healthy volunteers in comparison to buccal spray administration. J. Control. Release 266, 1–7 (2017).

102.        Cherniakov, I., Izgelov, D., Domb, A. J. & Hoffman, A. The effect of Pro NanoLipospheres (PNL) formulation containing natural absorption enhancers on the oral bioavailability of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in a rat model. Eur. J. Pharm. Sci. 109, 21–30 (2017).

103.        Aviv, O. et al. Cationic antimicrobial copolymer poly (methylmethacrylate-co-PHMG) decontaminates water. Polym. Adv. Technol. 28, 1334–1338 (2017).

104.        Abtew, E., Domb, A. J. & Basu, A. Synthesis of glycopeptides from glucosaminic acid. J. Polym. Sci. Part A Polym. Chem. 55, 2657–2662 (2017).

105.        Gold, D. et al. Elimination of Schistosoma mansoni in infected mice by slow release of artemisone. Int. J. Parasitol. Drugs Drug Resist. 7, 241–247 (2017).

106.        Basu, A., Nazarkovsky, M., Ghadi, R., Khan, W. & Domb, A. J. Poly(lactic acid)-based nanocomposites. Polym. Adv. Technol. 28, 919–930 (2017).

107.        Haim-Zada, M. et al. Stable polyanhydride synthesized from sebacic acid and ricinoleic acid. J. Control. Release 257, 156–162 (2017).

108.        Kagan, S., Ickowicz, D. E., Domb, A. J., Dagan, A. & Polacheck, I. Unique aggregation of conjugated amphotericin B and its interaction with lipid membranes. Med. Mycol. 55, 414–421 (2017).

109.        Barkan, Y. et al. Comparative evaluation of polycyanoacrylates. Acta Biomater. 48, 390–400 (2017).

110.        Kunduru, K. R. et al. Nanotechnology for water purification: applications of nanotechnology methods in wastewater treatment. in Water Purification 33–74 (Elsevier, 2017). doi:10.1016/B978-0-12-804300-4.00002-2.

111.        Beyth, N., Yudovin-Farber, I., Basu, A., Weiss, E. I. & Domb, A. J. Antimicrobial nanoparticles in restorative composites. in Emerging Nanotechnologies in Dentistry 41–58 (Elsevier, 2017). doi:10.1016/B978-0-12-812291-4.00003-0.

112.        Ghadi, R., Muntimadugu, E., Domb, A. J., Khan, W. & Zhang, X. Synthetic biodegradable medical polymer: Polyanhydrides. in Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties 153–188 (Elsevier Inc., 2017). doi:10.1016/B978-0-08-100372-5.00005-2.

113.        Kunduru, K. R., Basu, A., Tsah, T. & Domb, A. J. Polymer with pendant diazo-coupling functionality for colorimetric detection of nitrates. Sensors Actuators, B Chem. 251, 21–26 (2017).

114.        Kunduru, K. R., Basu, A., Abtew, E., Tsach, T. & Domb, A. J. Polymeric sensors containing P-dimethylaminocinnamaldehyde: Colorimetric detection of urea nitrate. Sensors Actuators, B Chem. 238, 387–391 (2017).

115.        Basu, A. et al. Discovering Novel and Diverse Iron-Chelators in Silico. J. Chem. Inf. Model. 56, 2476–2485 (2016).

116.        Langer, R., Basu, A. & Domb, A. J. Special issue: Polylactide (PLA) Based Biopolymers. Adv. Drug Deliv. Rev. 107, 1–2 (2016).

117.        Jain, A. et al. Injectable formulations of poly(lactic acid) and its copolymers in clinical use. Adv. Drug Deliv. Rev. 107, 213–227 (2016).

118.        Basu, A., Kunduru, K. R., Katzhendler, J. & Domb, A. J. Poly(α-hydroxy acid)s and poly(α-hydroxy acid-co-α-amino acid)s derived from amino acid. Adv. Drug Deliv. Rev. 107, 82–96 (2016).

119.        Basu, A., Kunduru, K. R., Doppalapudi, S., Domb, A. J. & Khan, W. Poly(lactic acid) based hydrogels. Adv. Drug Deliv. Rev. 107, 192–205 (2016).

120.        Ramot, Y., Haim-Zada, M., Domb, A. J. & Nyska, A. Biocompatibility and safety of PLA and its copolymers. Adv. Drug Deliv. Rev. 107, 153–162 (2016).

121.        Jain, A., Doppalapudi, S., Domb, A. J. & Khan, W. Tacrolimus and curcumin co-loaded liposphere gel: Synergistic combination towards management of psoriasis. J. Control. Release 243, 132–145 (2016).

122.        Basu, A., Haim-Zada, M. & Domb, A. J. Biodegradable inflatable balloons for tissue separation. Biomaterials 105, 109–116 (2016).

123.        Katiyar, S. S., Muntimadugu, E., Rafeeqi, T. A., Domb, A. J. & Khan, W. Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment. Drug Deliv. 23, 2608–2616 (2016).

124.        Eckhard, L. H. et al. Sustained release of antibacterial lipopeptides from biodegradable polymers against oral pathogens. PLoS One 11, (2016).

125.        Ramot, Y. et al. Preclinical Safety Evaluation in Rats of a Polymeric Matrix Containing an siRNA Drug Used as a Local and Prolonged Delivery System for Pancreatic Cancer Therapy. Toxicol. Pathol. 44, 856–865 (2016).

126.        Abtew, E., Domb, A. J. & Basu, A. Glycopeptides derived from glucosaminic acid. Polym. Chem. 7, 4447–4452 (2016).

127.        Aviv, O. et al. Poly(hexamethylene guanidine)-poly(ethylene glycol) solid blend for water microbial deactivation. Polym. Degrad. Stab. 129, 239–245 (2016).

128.        Haim-Zada, M. et al. Alternating Poly(ester-anhydride) by Insertion Polycondensation. Biomacromolecules 17, 2253–2259 (2016).

129.        Kunduru, K. R., Basu, A. & Domb, A. J. Biodegradable fatty acid polyesters. in Handbook of Polyester Drug Delivery Systems 33–59 (Pan Stanford Publishing Pte. Ltd., 2016). doi:10.4032/9789814669665.

130.        Doppalapudi, S., Jain, A., Domb, A. J. & Khan, W. Biodegradable polymers for targeted delivery of anti-cancer drugs. Expert Opin. Drug Deliv. 13, 891–909 (2016).

131.        Ghadi, R., Jain, A., Khan, W. & Domb, A. J. Microparticulate polymers and hydrogels for wound healing. in Wound Healing Biomaterials vol. 2 203–225 (Elsevier Inc., 2016).

132.        Basu, A., Kunduru, K. R., Abtew, E. & Domb, A. J. Erratum: Polysaccharide-Based Conjugates for Biomedical Applications (Bioconjugate Chemistry (2015) 26:8 (1396-1412) DOI: 10.1021/acs.bioconjchem.5b00242). Bioconjug. Chem. 27, 1427–1428 (2016).

133.        Ickowicz, D. E. et al. Poly(ester-anhydride) for controlled delivery of hydrophilic drugs. J. Bioact. Compat. Polym. 31, 127–139 (2016).

134.        Farah, S. et al. N-bromo-hydantoin grafted polystyrene beads: Synthesis and nano-micro beads characteristics for achieving controlled release of active oxidative bromine and extended microbial inactivation efficiency. J. Polym. Sci. Part A Polym. Chem. 54, 596–610 (2016).

135.        Basu, A. et al. Polyurethanes for Controlled Drug Delivery. in Advances in Polyurethane Biomaterials 217–246 (Elsevier Inc., 2016). doi:10.1016/B978-0-08-100614-6.00008-1.

136.        Basu, A. et al. PEG-Biscyanoacrylate Crosslinker for Octyl Cyanoacrylate Bioadhesive. Macromol. Rapid Commun. 37, 251–256 (2016).

137.        Ortega, A. et al. Antimicrobial evaluation of quaternary ammonium polyethyleneimine nanoparticles against clinical isolates of pathogenic bacteria. IET Nanobiotechnology 9, 342–348 (2015).

138.        Ramot, Y. et al. Long-term local and systemic safety of poly(l -lactide-co-epsilon-caprolactone) after subcutaneous and intra-articular implantation in rats. Toxicol. Pathol. 43, 1127–1140 (2015).

139.        Farah, S., Aviv, O., Laout, N., Ratner, S. & Domb, A. J. Antimicrobial N-brominated hydantoin and uracil grafted polystyrene beads. J. Control. Release 216, 18–29 (2015).

140.        Kunduru, K. R., Basu, A., Haim Zada, M. & Domb, A. J. Castor Oil-Based Biodegradable Polyesters. Biomacromolecules 16, 2572–2587 (2015).

141.        Farah, S., Kunduru, K. R., Basu, A. & Domb, A. J. Molecular Weight Determination of Polyethylene Terephthalate. in Poly(Ethylene Terephthalate) Based Blends, Composites and Nanocomposites 143–165 (Elsevier Inc., 2015). doi:10.1016/B978-0-323-31306-3.00008-7.

142.        Basu, A., Kunduru, K. R., Abtew, E. & Domb, A. J. Polysaccharide-Based Conjugates for Biomedical Applications. Bioconjug. Chem. 26, 1396–1412 (2015).

143.        Farah, S., Kunduru, K. R., Tsach, T., Bentolila, A. & Domb, A. J. Forensic comparison of synthetic fibers. Polym. Adv. Technol. 26, 785–796 (2015).

144.        Cherniakov, I., Domb, A. J. & Hoffman, A. Self-nano-emulsifying drug delivery systems: An update of the biopharmaceutical aspects. Expert Opin. Drug Deliv. 12, 1121–1133 (2015).

145.        Aviv, O. et al. N-Bromo-dimethylhydantoin Polystyrene Resin for Water Microbial Decontamination. Biomacromolecules 16, 1442–1447 (2015).

146.        Farah, S. et al. Quaternary ammonium poly(diethylaminoethyl methacrylate) possessing antimicrobial activity. Colloids Surfaces B Biointerfaces 128, 608–613 (2015).

147.        Farah, S. et al. Quaternary ammonium polyethylenimine nanoparticles for treating bacterial contaminated water. Colloids Surfaces B Biointerfaces 128, 614–619 (2015).

148.        Atar-Froyman, L. et al. Anti-biofilm properties of wound dressing incorporating nonrelease polycationic antimicrobials. Biomaterials 46, 141–148 (2015).

149.        Domb, A. J. Letter from the editor. Polym. Adv. Technol. 26, 213 (2015).

150.        Ramot, Y. et al. Interspecies differences in reaction to a biodegradable subcutaneous tissue filler: Severe inflammatory granulomatous reaction in the sinclair minipig. Toxicol. Pathol. 43, 267–271 (2015).

151.        Hosseinkhani, H., Abedini, F., Ou, K.-L. & Domb, A. J. Polymers in gene therapy technology. Polym. Adv. Technol. 26, 198–211 (2015).

152.        Gaikwad, D. D. et al. Synthesis of indazole motifs and their medicinal importance: An overview. Eur. J. Med. Chem. 90, 707–731 (2015).

153.        Shemi, A., Khvalevsky, E. Z., Gabai, R. M., Domb, A. & Barenholz, Y. Multistep, effective drug distribution within solid tumors. Oncotarget 6, 39564–39577 (2015).

154.        Jain, A., Hosseinkhani, H., Domb, A. J. & Khan, W. Cationic polymers for the delivery of therapeutic nucleotides. in Polysaccharides: Bioactivity and Biotechnology 1969–1990 (Springer International Publishing, 2015). doi:10.1007/978-3-319-16298-0_44.

155.        Golan, T. et al. RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients. Oncotarget 6, 24560–24570 (2015).

156.        Jain, A., Muntimadugu, E., Domb, A. J. & Khan, W. Cationic polysaccharides in gene delivery. RSC Polymer Chemistry Series vols 2015-January 228–248 (2015).

157.        Beyth, N., Houri-Haddad, Y., Domb, A., Khan, W. & Hazan, R. Alternative antimicrobial approach: Nano-antimicrobial materials. Evidence-based Complement. Altern. Med. 2015, (2015).

158.        Golovanevski, L., Ickowicz, D., Sokolsky-Papkov, M., Domb, A. & Weiniger, C. F. In vivo study of an extended release bupivacaine formulation following site-directed nerve injection. J. Bioact. Compat. Polym. 30, 114–125 (2015).

159.        Levinson, J. & Domb, A. J. RELIGION AND DISASTER VICTIM IDENTIFICATION. Med. Law 33, 55–60 (2014).

160.        Jain, A. et al. Antimicrobial Polymers. Adv. Healthc. Mater. 3, 1969–1985 (2014).

161.        Lendlein, A., Domb, A. J., Baudis, S. & Behl, M. From macromolecules to materials to systems. Polym. Adv. Technol. 25, 1187–1188 (2014).

162.        Ickowicz, D. E. et al. Castor oil-citric acid copolyester for tissue augmentation. Polym. Adv. Technol. 25, 1323–1328 (2014).

163.        He, W. et al. Polymeric nanoparticles for therapy and imaging. Polym. Adv. Technol. 25, 1216–1225 (2014).

164.        Lendlein, A., Behl, M. & Domb, A. J. Preface. Macromol. Symp. 345, 7 (2014).

165.        Eckhard, L. H. et al. Biohybrid Polymer-Antimicrobial Peptide Medium against Enterococcus faecalis. PLoS One 9, (2014).

166.        Ickowicz, D. E., Golovanevski, L., Domb, A. J. & Weiniger, C. F. Extended duration local anesthetic agent in a rat paw model. Int. J. Pharm. 468, 152–157 (2014).

167.        Ickowicz, D. E. et al. Activity, reduced toxicity, and scale-up synthesis of amphotericin B-conjugated polysaccharide. Biomacromolecules 15, 2079–2089 (2014).

168.        Farah, S. et al. Antimicrobial silica particles loaded with quaternary ammonium polyethyleneimine network. Polym. Adv. Technol. 25, 689–692 (2014).

169.        Lecht, S. et al. Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids. J. Biomater. Sci. Polym. Ed. 25, 608–624 (2014).

170.        Beyth, N., Farah, S., Domb, A. J. & Weiss, E. I. Antibacterial dental resin composites. React. Funct. Polym. 75, 81–88 (2014).

171.        Domb, A. J. Biodegradable polymers in medicine. Polym. Adv. Technol. 25, 425–426 (2014).

172.        Doppalapudi, S., Jain, A., Khan, W. & Domb, A. J. Biodegradable polymers-an overview. Polym. Adv. Technol. 25, 427–435 (2014).

173.        Eameema, M., Duvvuri, L. S., Khan, W. & Domb, A. J. Polyanhydrides. in Natural and Synthetic Biomedical Polymers 181–192 (Elsevier Inc., 2014). doi:10.1016/B978-0-12-396983-5.00010-7.

174.        Farber, S. et al. Surface functionalization of magnetic nanoparticles formed by self-associating hydrophobized oxidized dextrans. J. Nanoparticle Res. 16, (2014).

175.        Pawar, R. P., Tekale, S. U., Shisodia, S. U., Totre, J. T. & Domb, A. J. Biomedical applications of poly(lactic acid). Rec. Pat. Regen. Med. 4, 40–51 (2014).

176.        Yeo, W. W. Y. et al. Safety profile of dextran-spermine gene delivery vector in mouse lungs. J. Nanosci. Nanotechnol. 14, 3328–3336 (2014).

177.        Sosna, J. et al. Computed tomography of Lipiodol-loaded biodegradable pasty polymer for implant visualization. Contrast Media Mol. Imaging 9, 246–251 (2014).

178.        Farah, S., Tsach, T., Bentolila, A. & Domb, A. J. Morphological, spectral and chromatography analysis and forensic comparison of PET fibers. Talanta 123, 54–62 (2014).

179.        Ickowicz, D. E., Golovanevski, L., Haze, A., Domb, A. J. & Weiniger, C. F. Extended release local anesthetic agents in a postoperative arthritic pain model. J. Pharm. Sci. 103, 185–190 (2014).

180.        Khvalevsky, E. Z. et al. Mutant KRAS is a druggable target for pancreatic cancer. Proc. Natl. Acad. Sci. U. S. A. 110, 20723–20728 (2013).

181.        Muntimadugu, E., Ickowicz, D. E., Domb, A. J. & Khan, W. Polysaccharide biomaterials. Isr. J. Chem. 53, 787–794 (2013).

182.        Elgart, A., Cherniakov, I., Aldouby, Y., Domb, A. J. & Hoffman, A. Improved oral bioavailability of BCS class 2 compounds by self nano-emulsifying drug delivery systems (SNEDDS): The underlying mechanisms for amiodarone and talinolol. Pharm. Res. 30, 3029–3044 (2013).

183.        Cohen-Arazi, N., Domb, A. J. & Katzhendler, J. Poly(α-hydroxy alkanoic acid)s derived from α-amino acids. Macromol. Biosci. 13, 1689–1699 (2013).

184.        Aviv, O. et al. Controlled iodine release from polyurethane sponges for water decontamination. J. Control. Release 172, 634–640 (2013).

185.        Kuklev, D. V, Domb, A. J. & Dembitsky, V. M. Bioactive acetylenic metabolites. Phytomedicine 20, 1145–1159 (2013).

186.        Saravanan, M. & Domb, A. J. A contemporary review on - Polymer stereocomplexes and its biomedical application. Eur. J. Nanomedicine 5, 81–96 (2013).

187.        Hosseinkhani, H. et al. Biodegradable nanoparticles for gene therapy technology. J. Nanoparticle Res. 15, (2013).

188.        Han, J., Farah, S., Domb, A. J. & Lelkes, P. I. Electrospun Rapamycin-Eluting Polyurethane Fibers for Vascular Grafts. Pharm. Res. 30, 1735–1748 (2013).

189.        Bentolila, A., Totre, J., Zozulia, I., Levin-Elad, M. & Domb, A. J. Fluorescent cyanoacrylate monomers and polymers for fingermark development. Macromolecules 46, 4822–4828 (2013).

190.        Amini, R. et al. Dynamics of PEGylated-dextran-spermine nanoparticles for gene delivery to leukemic cells. Appl. Biochem. Biotechnol. 170, 841–853 (2013).

191.        Khan, W., Farah, S., Nyska, A. & Domb, A. J. Carrier free rapamycin loaded drug eluting stent: In vitro and in vivo evaluation. J. Control. Release 168, 70–76 (2013).

192.        Vaisman, B. et al. In vivo degradation and elimination of injectable ricinoleic acid-based poly(ester-anhydride). Biomacromolecules 14, 1465–1473 (2013).

193.        Wiesner, S., Izraeli, E., Shor, Y. & Domb, A. Lifting Bloody Footwear Impressions Using Alginate Casts Followed by Chemical Enhancement. J. Forensic Sci. 58, 782–788 (2013).

194.        Farah, S. et al. Crosslinked QA-PEI nanoparticles: Synthesis reproducibility, chemical modifications, and stability study. Polym. Adv. Technol. 24, 446–452 (2013).

195.        Khan, W., Muthupandian, S. & Domb, A. J. Cationic polymers for the delivery of therapeutic nucleotides. in Nanotechnology for the Delivery of Therapeutic Nucleic Acids 27–56 (Pan Stanford Publishing Pte. Ltd., 2013). doi:10.4032/9789814411059.

196.        Farah, S., Khan, W. & Domb, A. J. Crystalline coating of rapamycin onto a stent: Process development and characterization. Int. J. Pharm. 445, 20–28 (2013).

197.        Domb, A. J., Beyth, N. & Farah, S. Quaternary ammonium antimicrobial polymers. in 2013 MRS Spring Meeting vol. 1569 (Materials Research Society, 2013).

198.        Ameta, K. L., Pawar, R. P. & Domb, A. J. Preface. Bioact. Heterocycles Synth. Biol. Eval. (2013).

199.        Ameta, K. L., Pawar, R. P. & Domb, A. J. Bioactive heterocycles: Synthesis and biological evaluation. Bioactive Heterocycles: Synthesis and Biological Evaluation (Nova Science Publishers, Inc., 2013).

200.        Sarda, S. R. et al. Synthesis and biological evaluation of flavones. in Bioactive Heterocycles: Synthesis and Biological Evaluation 235–258 (Nova Science Publishers, Inc., 2013).

201.        Domb, A. J. & Khan, W. Biodegradable polymers as drug carrier systems. in Polymeric Biomaterials: Structure and Function vol. 1 135–165 (CRC Press, 2013).

202.        Hiremath, J. G., Rajeshkumar, A., Ickowicz, D. & Domb, A. J. Preparation and in vitro characterization of paclitaxel containing poly(lactic acid co-castor oil)-based nanodispersions. J. Drug Deliv. Sci. Technol. 23, 439–444 (2013).

203.        Thipparaboina, R., Khan, W. & Domb, A. J. Eluting combination drugs from stents. Int. J. Pharm. 454, 4–10 (2013).

204.        Levinson, J. & Domb, A. Disaster victim identification In Israel: A multi-disciplinary approach. Anil Aggrawal’s Internet J. Forensic Med. Toxicol. 14, (2013).

205.        Hosseinkhani, H. et al. Engineering of magnetic DNA nanoparticles for tumor-targeted therapy. J. Nanoparticle Res. 15, (2013).

206.        Abedini, F. et al. Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer. Int. J. Nanomedicine 7, 4159–4168 (2012).

207.        Hosseinkhani, H. et al. Development of 3D in vitro platform technology to engineer mesenchymal stem cells. Int. J. Nanomedicine 7, 3035–3043 (2012).

208.        Beyth, N., Yudovin-Farber, I., Weiss, E. I. & Domb, A. J. Antimicrobial Nanoparticles in Restorative Composites. in Emerging Nanotechnologies in Dentistry 35–47 (Elsevier Inc., 2012). doi:10.1016/B978-1-4557-7862-1.00003-1.

209.        Gref, R. et al. The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres. Adv. Drug Deliv. Rev. 64, 316–326 (2012).

210.        Kagan, S. et al. Toxicity mechanisms of amphotericin B and its neutralization by conjugation with arabinogalactan. Antimicrob. Agents Chemother. 56, 5603–5611 (2012).

211.        Khan, W., Aldouby, Y. H., Avramoff, A. & Domb, A. J. Cyclosporin nanosphere formulation for ophthalmic administration. Int. J. Pharm. 437, 275–276 (2012).

212.        Avramoff, A., Khan, W., Mizrahi, B. & Domb, A. J. Preparation and characterization of a novel once-daily formulation of diltiazem using arabinogalactan as a channeling agent. J. Appl. Polym. Sci. 126, E197–E203 (2012).

213.        Levy-Nissenbaum, E. et al. Pharmacokinetic and efficacy study of cisplatin and paclitaxel formulated in a new injectable poly(sebacic-co-ricinoleic acid) polymer. Eur. J. Pharm. Biopharm. 82, 85–93 (2012).

214.        Weiniger, C. F., Golovanevski, L., Domb, A. J. & Ickowicz, D. Extended release formulations for local anaesthetic agents. Anaesthesia 67, 906–916 (2012).

215.        Khan, W., Farah, S. & Domb, A. J. Drug eluting stents: Developments and current status. J. Control. Release 161, 703–712 (2012).

216.        Hiremath, J. G., Rudani, C. G., Domb, A. J., Suthar, R. V & Khamar, N. S. Preparation and in vitro characterization of poly(sebacic acid-co-ricinoleic acid)-based tamoxifen citrate-loaded microparticles for breast cancer. J. Appl. Polym. Sci. 124, 4747–4754 (2012).

217.        Avramoff, A. et al. Cyclosporin pro-dispersion liposphere formulation. J. Control. Release 160, 401–406 (2012).

218.        Elgart, A., Cherniakov, I., Aldouby, Y., Domb, A. J. & Hoffman, A. Lipospheres and pro-nano lipospheres for delivery of poorly water soluble compounds. Chem. Phys. Lipids 165, 438–453 (2012).

219.        Levy, Y., Khan, W., Farah, S. & Domb, A. J. Surface crystallization of rapamycin on stents using a temperature induced process. Langmuir 28, 6207–6210 (2012).

220.        Khan, W. et al. Polysaccharide gene transfection agents. Acta Biomater. 8, 4224–4232 (2012).

221.        Sokolsky-Papkov, M., Golovanevski, L., Domb, A. J. & Weiniger, C. F. Erratum: Sokolsky-Papkov M, Golovanevski L, Domb A, Weiniger C. 2010. Poly(d,l:lactic-acid-castor oil) 3:7-bupivacaine formulation: Reducing burst effect prolongs efficacy in vivo. J Pharm Sci 99:2732-2738. J. Pharm. Sci. 101, 884 (2012).

222.        Khan, W., Muthupandian, S., Farah, S., Kumar, N. & Domb, A. J. Biodegradable polymers derived from amino acids. Macromol. Biosci. 11, 1625–1636 (2011).

223.        Sokolsky-Papkov, M., Golovanevski, L., Domb, A. J. & Weiniger, C. F. Long-acting poly(DL:lactic acid-castor oil) 3:7-bupivacaine formulation: Effect of hydrophobic additives. Pharm. Res. 28, 3265–3273 (2011).

224.        Beyth, N., Yudovin-Farber, I., Weiss, E. I. & Domb, A. J. Antimicrobial Nanoparticles in Restorative Composites. in Emerging Nanotechnologies in Dentistry: Processes, Materials and Applications 35–47 (Elsevier, 2011). doi:10.1016/B978-1-4557-7862-1.00003-1.

225.        Abedini, F. et al. Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver. Cancer Manag. Res. 3, 301–309 (2011).

226.        Domb, A., Jain, J. P. & Kumar, N. Polyanhydrides. in Handbook of Biodegradable Polymers: Isolation, Synthesis, Characterization and Applications 45–75 (Wiley-VCH, 2011). doi:10.1002/9783527635818.ch3.

227.        Domb, A. J., Kumar, N. & Ezra, A. Biodegradable Polymers in Clinical Use and Clinical Development. Biodegradable Polymers in Clinical Use and Clinical Development (John Wiley and Sons, 2011). doi:10.1002/9781118015810.

228.        Pawar, R. P. et al. Arabinogalactan in Clinical Use. in Biodegradable Polymers in Clinical Use and Clinical Development 217–245 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch7.

229.        Khan, W., Yadav, D., Domb, A. J. & Kumar, N. Collagen. in Biodegradable Polymers in Clinical Use and Clinical Development 59–89 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch2.

230.        Borade, R. M., Domb, A. J., Sawale, A. A., Pawar, R. P. & Kharat, K. R. Polyanhydrides-Poly(CPP-SA), Fatty-Acid-Based Polyanhydrides. in Biodegradable Polymers in Clinical Use and Clinical Development 367–400 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch10.

231.        Totre, J., Ickowicz, D. & Domb, A. J. Properties and Hemostatic Application of Gelatin. in Biodegradable Polymers in Clinical Use and Clinical Development 91–109 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch3.

232.        Jain, J. P., Yenet Ayen, W., Domb, A. J. & Kumar, N. Biodegradable Polymers in Drug Delivery. in Biodegradable Polymers in Clinical Use and Clinical Development 1–58 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch1.

233.        Pawar, R. P., Jadhav, A. E., Tathe, S. B., Khade, B. C. & Domb, A. J. Medicinal Applications of Cyanoacrylate. in Biodegradable Polymers in Clinical Use and Clinical Development 417–449 (John Wiley and Sons, 2011). doi:10.1002/9781118015810.ch12.

234.        Sokolsky-Papkov, M., Langer, R. & Domb, A. J. Synthesis of aliphatic polyesters by polycondensation using inorganic acid as catalyst. Polym. Adv. Technol. 22, 502–511 (2011).

235.        Hiremath, J. G., Rudani, C. G., Suthar, R. V & Domb, A. J. Tamoxifen citrate loaded biodegradable poly(sebacic acid-co-ricinoleic acid) microparticles, in vitro characterization. J. Drug Deliv. Sci. Technol. 21, 417–422 (2011).

236.        Abedini, F. et al. In vitro intracellular trafficking of biodegradable nanoparticles dextran-spermine in cancer cell lines. Int. J. Nanotechnol. 8, 712–723 (2011).

237.        Hosseinkhani, H., Hosseinkhani, M., Chen, Y.-R., Subramani, K. & Domb, A. J. Innovative technology of engineering magnetic DNA nanoparticles for gene therapy. Int. J. Nanotechnol. 8, 724–735 (2011).

238.        Yudovin-Farber, I., Eliyahu, H. & Domb, A. J. Synthesis of cationic polysaccharides and use for in vitro transfection. Cold Spring Harb. Protoc. 6, (2011).

239.        Domb, A. J. Tenth PAT symposium, Jerusalem, 2009: In honor of Professor Menachem Lewin’s 90th birthday. Polym. Adv. Technol. 22, 1–2 (2011).

240.        Farber, S. et al. Galactomannan-amphotericin B conjugate: Synthesis and biological activity. Polym. Adv. Technol. 22, 119–125 (2011).

241.        Havivi, E., Farber, S. & Domb, A. J. Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for delivery of tamsulosin hydrochloride. Polym. Adv. Technol. 22, 114–118 (2011).

242.        Verma, S., Domb, A. J. & Kumar, N. Nanomaterials for regenerative medicine. Nanomedicine 6, 157–181 (2011).

243.        Beyth, N., Yudovin-Farber, I., Perez-Davidi, M., Domb, A. J. & Weiss, E. I. Polyethyleneimine nanoparticles incorporated into resin composite cause cell death and trigger biofilm stress in vivo. Proc. Natl. Acad. Sci. U. S. A. 107, 22038–22043 (2010).

244.        Okner, R., Favaro, G., Radko, A., Domb, A. J. & Mandler, D. Electrochemical codeposition of sol-gel films on stainless steel: Controlling the chemical and physical coating properties of biomedical implants. Phys. Chem. Chem. Phys. 12, 15265–15273 (2010).

245.        Cohen-Arazi, N., Domb, A. J. & Katzhendler, J. New biocompatible polyesters derived from α-amino acids: Hydrolytic degradation behavior. Polymers (Basel). 2, 418–439 (2010).

246.        Abdullah, S. et al. Gene transfer into the lung by nanoparticle dextran-spermine/plasmid DNA complexes. J. Biomed. Biotechnol. 2010, (2010).

247.        Domb, A. J., Yudovin-Farber, I., Golenser, J., Beyth, N. & Weiss, E. I. Quaternary ammonium polyethyleneimine: Antibacterial activity. J. Nanomater. 2010, (2010).

248.        Elgart, A., Farber, S., Domb, A. J., Polacheck, I. & Hoffman, A. Polysaccharide pharmacokinetics: Amphotericin B arabinogalactan conjugate-A drug delivery system or a new pharmaceutical entity? Biomacromolecules 11, 1972–1977 (2010).

249.        Łukaszczyk, J., Jelonek, P., Trzebicka, B. & Domb, A. J. Stereocomplexes formation from enantiomeric star-shaped block copolymers of ε-caprolactone and lactide. E-Polymers (2010) doi:10.1515/epoly.2010.10.1.798.

250.        Pawar, R. P., Kharat, K. R. & Domb, A. J. Pasty polymers in cancer drug therapy. Isr. J. Chem. 50, 233–238 (2010).

251.        Zhang, J., Li, C., Duan, Y., Domb, A. J. & Ozaki, Y. Glass transition and disorder-to-order phase transition behavior of poly(l-lactic acid) revealed by infrared spectroscopy. Vib. Spectrosc. 53, 307–310 (2010).

252.        Weiniger, C. F., Golovanevski, M., Sokolsky-Papkov, M. & Domb, A. J. Review of prolonged local anesthetic action. Expert Opin. Drug Deliv. 7, 737–752 (2010).

253.        Zhang, J., Duan, Y., Domb, A. J. & Ozaki, Y. PLLA mesophase and its phase transition behavior in the PLLA-PEG-PLLA copolymer as revealed by infrared spectroscopy. Macromolecules 43, 4240–4246 (2010).

254.        Eljarrat-Binstock, E., Pe’er, J. & Domb, A. J. New techniques for drug delivery to the posterior eye segment. Pharm. Res. 27, 530–543 (2010).

255.        Shikanov, A., Vaisman, B., Shikanov, S. & Domb, A. J. Efficacy of poly(sebacic acid-co-ricinoleic acid) biodegradable delivery system for intratumoral delivery of paclitaxel. J. Biomed. Mater. Res. - Part A 92, 1283–1291 (2010).

256.        Vaisman, B., Motiei, M., Nyska, A. & Domb, A. J. Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats. J. Biomed. Mater. Res. - Part A 92, 419–431 (2010).

257.        Pinhassi, R. I. et al. Arabinogalactan-folic acid-drug conjugate for targeted delivery and target-activated release of anticancer drugs to folate receptor-overexpressing cells. Biomacromolecules 11, 294–303 (2010).

258.        Pawar, R. P., Shinde, N. R., Andurkar, N. M., Dake, S. A. & Domb, A. J. Injectable polymers for regional drug delivery. in Targeted Delivery of Small and Macromolecular Drugs 457–480 (CRC Press, 2010). doi:10.1201/9781420087734.

259.        Beyth, N., Yudovin-Fearber, I., Domb, A. J. & Weiss, E. I. Long-term antibacterial surface properties of composite resin incorporating polyethyleneimine nanoparticles. Quintessence Int. (Berl). 41, 827–835 (2010).

260.        Yudovin-Farber, I., Beyth, N., Weiss, E. I. & Domb, A. J. Antibacterial effect of composite resins containing quaternary ammonium polyethyleneimine nanoparticles. J. Nanoparticle Res. 12, 591–603 (2010).

261.        Aframian, D. J., Mizrahi, B., Granot, I. & Domb, A. J. Evaluation of a mucoadhesive lipid-based bioerodable tablet compared with Biotène mouthwash for dry mouth relief-A pilot study. Quintessence Int. (Berl). 41, e36–e42 (2010).

262.        Sokolsky-Papkov, M., Golovanevski, L., Domb, A. J. & Weiniger, C. F. Poly(DL:lactic acid-castor oil) 3:7-bupivacaine formulation: Reducing burst effect prolongs efficacy in vivo. J. Pharm. Sci. 99, 2732–2738 (2010).

263.        Avramoff, A. & Domb, A. J. In-vitro and in-vivo characteristics of a modified-release double-pulse formulation for a water soluble drug. Int. J. Clin. Pharmacol. Ther. 48, 250–258 (2010).

264.        Srichana, T. & Domb, A. J. Polymeric biomaterials. in Biomedical Materials 83–119 (Springer US, 2009). doi:10.1007/978-0-387-84872-3_3.

265.        Shaulov, Y. et al. Poly(methyl methacrylate) grafting onto stainless steel surfaces: Application to drug-eluting stents. ACS Appl. Mater. Interfaces 1, 2519–2528 (2009).

266.        Veronesi, M. C., Aldouby, Y., Domb, A. J. & Kubek, M. J. Thyrotropin-releasing hormone d,l polylactide nanoparticles (TRH-NPs) protect against glutamate toxicity in vitro and kindling development in vivo. Brain Res. 1303, 151–160 (2009).

267.        Yudovin-Farber, I., Gurt, I., Hope, R., Domb, A. J. & Katz, E. Inhibition of herpes simplex virus by polyamines. Antivir. Chem. Chemother. 20, 87–98 (2009).

268.        Levy, Y. et al. Biodegradable inflatable balloon for reducing radiation adverse effects in prostate cancer. J. Biomed. Mater. Res. - Part B Appl. Biomater. 91, 855–867 (2009).

269.        Levy, Y. et al. Drug-eluting stent with improved durability and controllability properties, obtained via electrocoated adhesive promotion layer. J. Biomed. Mater. Res. - Part B Appl. Biomater. 91, 819–830 (2009).

270.        Farber, S., Green, B. S. & Domb, A. J. Selective 17-β-estradiol molecular imprinting. J. Polym. Sci. Part A Polym. Chem. 47, 5534–5542 (2009).

271.        Levy, Y., Mandler, D., Weinberger, J. & Domb, A. J. Evaluation of drug-eluting stents’ coating durability - Clinical and regulatory implications. J. Biomed. Mater. Res. - Part B Appl. Biomater. 91, 441–451 (2009).

272.        Slager, J. et al. Local controlled delivery of anti-neoplastic RNAse to the brain. Pharm. Res. 26, 1838–1846 (2009).

273.        Kolitz, M., Cohen-Arazi, N., Hagag, H., Katzhendler, J. & Domb, A. J. Biodegradable polyesters derived from amino acids. Macromolecules 42, 4520–4530 (2009).

274.        Okner, R. et al. Electropolymerized tricopolymer based on N-pyrrole derivatives as a primer coating for improving the performance of a drug-eluting stent. ACS Appl. Mater. Interfaces 1, 758–767 (2009).

275.        Mizrahi, B. & Domb, A. J. Anhydride prodrug of ibuprofen and acrylic polymers. AAPS PharmSciTech 10, 453–458 (2009).

276.        Brin, Y. S. et al. Biocompatibility of a polymeric implant for the treatment of osteomyelitis. J. Biomater. Sci. Polym. Ed. 20, 1081–1090 (2009).

277.        Kubek, M. J., Domb, A. J. & Veronesi, M. C. Attenuation of Kindled Seizures by Intranasal Delivery of Neuropeptide-Loaded Nanoparticles. Neurotherapeutics 6, 359–371 (2009).

278.        Ben-Yosef, R. et al. A Novel Device for Protecting Rectum During Prostate Cancer Irradiation: In Vivo Data on a Large Mammal Model. J. Urol. 181, 1401–1406 (2009).

279.        Okner, R. et al. Electrocoating of stainless steel coronary stents for extended release of paclitaxel. J. Biomed. Mater. Res. - Part A 88, 427–436 (2009).

280.        Sokolsky-Papkov, M., Shikanov, A., Ezra, A., Vaisman, B. & Domb, A. J. Fatty acid-based biodegradable polymers: Synthesis and applications. ACS Symposium Series vol. 1004 60–69 (2009).

281.        Okner, R., Domb, A. J. & Mandler, D. Electrochemically deposited poly(ethylene glycol)-based sol-gel thin films on stainless steel stents. New J. Chem. 33, 1596–1604 (2009).

282.        Shikanov, S. et al. Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer. J. Pharm. Sci. 98, 1005–1014 (2009).

283.        Sokolsky-Papkov, M., Golovanevski, L., Domb, A. J. & Weiniger, C. F. Prolonged local anesthetic action through slow release from poly(lactic acid co castor oil). Pharm. Res. 26, 32–39 (2009).

284.        Eljarrat-Binstock, E. et al. In vitro and in vivo evaluation of carboplatin delivery to the eye using hydrogel-iontophoresis. Curr. Eye Res. 33, 269–275 (2008).

285.        Yudovin-Farber, I. et al. Surface characterization and biocompatibility of restorative resin containing nanoparticles. Biomacromolecules 9, 3044–3050 (2008).

286.        Beyth, N. et al. Surface antimicrobial activity and biocompatibility of incorporated polyethylenimine nanoparticles. Biomaterials 29, 4157–4163 (2008).

287.        Cohen-Arazi, N., Katzhendler, J., Kolitz, M. & Domb, A. J. Preparation of new α-hydroxy acids derived from amino acids and their corresponding polyesters. Macromolecules 41, 7259–7263 (2008).

288.        Brin, Y. S. et al. Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin. J. Control. Release 131, 121–127 (2008).

289.        Perez Davidi, M. et al. The effect of a mild increase in temperature on tooth bleaching. Quintessence Int. (Berl). 39, 771–775 (2008).

290.        Mizrahi, B., Shavit, R. & Domb, A. J. Synthesis and characterization of polymeric implant for kyphoplasty. J. Biomed. Mater. Res. - Part B Appl. Biomater. 86, 466–473 (2008).

291.        Sterer, N. et al. Oral malodor reduction by a palatal mucoadhesive tablet containing herbal formulation. J. Dent. 36, 535–539 (2008).

292.        Shikanov, A., Shikanov, S., Vaisman, B., Golenser, J. & Domb, A. J. Paclitaxel tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant. Int. J. Pharm. 358, 114–120 (2008).

293.        Mizrahi, B. & Domb, A. J. Mucoadhesive polymers for delivery of drugs to the oral cavity. Recent Patents Drug Deliv. Formul. 2, 108–119 (2008).

294.        Sokolsky-Papkov, M. & Domb, A. J. Stereoisomeric effect on in vitro drug release from injectable poly(lactic acid co castor oil) polyesters. Polym. Adv. Technol. 19, 671–679 (2008).

295.        Eljarrat-Binstock, E., Orucov, F., Frucht-Pery, J., Pe’er, J. & Domb, A. J. Methylprednisolone delivery to the back of the eye using hydrogel iontophoresis. J. Ocul. Pharmacol. Ther. 24, 344–350 (2008).

296.        Beyth, N., Bahir, R., Matalon, S., Domb, A. J. & Weiss, E. I. Streptococcus mutans biofilm changes surface-topography of resin composites. Dent. Mater. 24, 732–736 (2008).

297.        Hiremath, J. G., Kusum Devi, V., Devi, K. & Domb, A. J. Biodegradable poly(sebacic acid-co-ricinoleic-ester anhydride) tamoxifen citrate implants: Preparation and in vitro characterization. J. Appl. Polym. Sci. 107, 2745–2754 (2008).

298.        Eljarrat-Binstock, E., Orucov, F., Aldouby, Y., Frucht-Pery, J. & Domb, A. J. Charged nanoparticles delivery to the eye using hydrogel iontophoresis. J. Control. Release 126, 156–161 (2008).

299.        Zhang, J., Tashiro, K., Tsuji, H. & Domb, A. J. Disorder-to-order phase transition and multiple melting behavior of poly(L-lactide) investigated by simultaneous measurements of WAXD and DSC. Macromolecules 41, 1352–1357 (2008).

300.        Vaisman, B., Shikanov, A. & Domb, A. J. The isolation of ricinoleic acid from castor oil by salt-solubility-based fractionation for the biopharmaceutical applications. JAOCS, J. Am. Oil Chem. Soc. 85, 169–184 (2008).

301.        Pawar, R. et al. Polysaccharides as carriers of bioactive agents for medical applications. in Natural-Based Polymers for Biomedical Applications 3–53 (Elsevier Ltd., 2008). doi:10.1533/9781845694814.1.3.

302.        Berger, R. et al. Cyclosporine safety and bioavailability with two second-generation softgel capsules using serum concentrations/TDM and modeling in transplant patients - A retrospective, parallel, comparative evaluation study. Int. J. Clin. Pharmacol. Ther. 46, 165–171 (2008).

303.        Jain, J. P., Sokolsky, M., Kumar, N. & Domb, A. J. Fatty acid based biodegradable polymer. Polym. Rev. 48, 156–191 (2008).

304.        Shemer, A. et al. Efficacy of a mucoadhesive patch compared with an oral solution for treatment of aphthous stomatitis. Drugs R D 9, 29–35 (2008).

305.        Krasko, M. Y. & Domb, A. J. Pasty injectable biodegradable polymers derived from natural acids. J. Biomed. Mater. Res. - Part A 83, 1138–1145 (2007).

306.        Fay, F. et al. Protecting biodegradable coatings releasing antimicrobial agents. J. Appl. Polym. Sci. 106, 3768–3777 (2007).

307.        Okner, R., Domb, A. J. & Mandler, D. Electrochemical formation and characterization of copolymers based on N-pyrrole derivatives. Biomacromolecules 8, 2928–2935 (2007).

308.        Eljarrat-Binstock, E., Bentolila, A., Kumar, N., Harel, H. & Domb, A. J. Preparation, characterization, and sterilization of hydrogel sponges for iontophoretic drug-delivery use. Polym. Adv. Technol. 18, 720–730 (2007).

309.        Marom, G. & Domb, A. J. In memory of Professor Yair Avny (1937-2006). Polym. Adv. Technol. 18, 679–680 (2007).

310.        Shustak, G., Shaulov, Y., Domb, A. J. & Mandler, D. Electrostatic attachment of gold and poly(lactic acid) nanoparticles onto ω-aminoalkanoic acid self-assembled monolayers on 316l stainless steel. Chem. - A Eur. J. 13, 6402–6407 (2007).

311.        Eljarrat-Binstock, E., Domb, A. J., Orucov, F., Frucht-Pery, J. & Pe’er, J. Methotrexate delivery to the eye using transscleral hydrogel iontophoresis. Curr. Eye Res. 32, 639–646 (2007).

312.        Zhang, J., Beshra, A., Domb, A. J. & Ozaki, Y. d-Poly(lactide) and LHRH decapeptide stereointeractions investigated by vibrational spectroscopy. Eur. Polym. J. 43, 3016–3027 (2007).

313.        Sokolsky-Papkov, M., Agashi, K., Olaye, A., Shakesheff, K. & Domb, A. J. Polymer carriers for drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 59, 187–206 (2007).

314.        Domb, A. & Mikos, A. G. Matrices and scaffolds for drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 59, 185–186 (2007).

315.        Eliyahu, H. et al. Characterization and in vivo performance of dextran-spermine polyplexes and DOTAP/cholesterol lipoplexes administered locally and systemically. Biomaterials 28, 2339–2349 (2007).

316.        Yudovin-Farber, I. & Domb, A. J. Cationic polysaccharides for gene delivery. Mater. Sci. Eng. C 27, 595–598 (2007).

317.        Okner, R., Oron, M., Tal, N., Mandler, D. & Domb, A. J. Electrocoating of stainless steel coronary stents for extended release of Paclitaxel. Mater. Sci. Eng. C 27, 510–513 (2007).

318.        Schumacher, I. et al. Quality and stability evaluation of disposable medical equipment. Polym. Adv. Technol. 18, 207–212 (2007).

319.        Beyth, N., Domb, A. J. & Weiss, E. I. An in vitro quantitative antibacterial analysis of amalgam and composite resins. J. Dent. 35, 201–206 (2007).

320.        Zhang, J., Tashiro, K., Tsuji, H. & Domb, A. J. Investigation of phase transitional behavior of poly(L-lactide)/ poly(D-lactide) blend used to prepare the highly-oriented stereocomplex. Macromolecules 40, 1049–1054 (2007).

321.        Krasko, M. Y. et al. Gentamicin extended release from an injectable polymeric implant. J. Control. Release 117, 90–96 (2007).

322.        Shikanov, A., Domb, A. J. & Weiniger, C. F. Long acting local anesthetic-polymer formulation to prolong the effect of analgesia. J. Control. Release 117, 97–103 (2007).

323.        Mittal, A. et al. Polymeric Carriers for Regional Drug Therapy. in Smart Polymers: Applications in Biotechnology and Biomedicine 359–400 (CRC Press, 2007). doi:10.1201/9781420008623-17.

324.        Mizrahi, B. & Domb, A. J. Mucoadhesive tablet releasing iodine for treating oral infections. J. Pharm. Sci. 96, 3144–3150 (2007).

325.        Raiskup-Wolf, F., Eljarrat-Binstock, E., Rehák, M., Domb, A. & Frucht-Pery, J. Transcorneal and transscleral iontophoresis of the dexamethasone phosphate into the rabbit eye . Ces. a Slov. Oftalmol. 63, 360–368 (2007).

326.        Avramoff, A., Laor, A., Kitzes-Cohen, R., Farin, D. & Domb, A. J. Comparative in vivo bioequivalence and in vitro dissolution of two cyclosporin A soft gelatin capsule formulations. Int. J. Clin. Pharmacol. Ther. 45, 126–132 (2007).

327.        Shustak, G., Gadzinowski, M., Slomkowski, S., Domb, A. J. & Mandler, D. A novel electrochemically synthesized biodegradable thin film of polypyrrole-polyethyleneglycol-polylactic acid nanoparticles. New J. Chem. 31, 163–168 (2007).

328.        Zhang, J., Tashiro, K., Domb, A. J. & Tsuji, H. Confirmation of disorder α form of poly(L-lactic acid) by the X-ray fiber pattern and polarized IR/Raman spectra measured for uniaxially-oriented samples. Macromol. Symp. 242, 274–278 (2006).

329.        Chitkara, D., Shikanov, A., Kumar, N. & Domb, A. J. Biodegradable injectable in situ depot-forming drug delivery systems. Macromol. Biosci. 6, 977–990 (2006).

330.        Ben-Shabat, S., Kumar, N. & Domb, A. J. PEG-PLA block copolymer as potential drug carrier: Preparation and characterization. Macromol. Biosci. 6, 1019–1025 (2006).

331.        Frucht-Pery, J. et al. Iontophoretic treatment of experimental pseudomonas keratitis in rabbit eyes using gentamicin-loaded hydrogels. Cornea 25, 1182–1186 (2006).

332.        Modi, S., Jain, J. P., Domb, A. J. & Kumar, N. Exploiting EPR in polymer drug conjugate delivery for tumor targeting. Curr. Pharm. Des. 12, 4785–4796 (2006).

333.        Gafni, Y. et al. Design of a filamentous polymeric scaffold for in vivo guided angiogenesis. Tissue Eng. 12, 3021–3034 (2006).

334.        Modi, S., Jain, J. P., Domb, A. J. & Kumar, N. Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility. Eur. J. Pharm. Biopharm. 64, 277–286 (2006).

335.        Ben-Shabat, S. & Domb, A. J. Synthesis of pendent carbonate ester groups onto aliphatic polycarbonates. J. Bioact. Compat. Polym. 21, 385–397 (2006).

336.        Krasko, M. Y., Kumar, N. & Domb, A. J. Protein and peptide release from in situ gelling polymer. Biomacromolecules 7, 2461–2463 (2006).

337.        Hosseinkhani, H. et al. Combination of 3D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells. Biomaterials 27, 4269–4278 (2006).

338.        Chorny, M., Mishaly, D., Leibowitz, A., Domb, A. J. & Golomb, G. Site-specific delivery of dexamethasone from biodegradable implants reduces formation of pericardial adhesions in rabbits. J. Biomed. Mater. Res. - Part A 78, 276–282 (2006).

339.        Beyth, N., Yudovin-Farber, I., Bahir, R., Domb, A. J. & Weiss, E. I. Antibacterial activity of dental composites containing quaternary ammonium polyethylenimine nanoparticles against Streptococcus mutans. Biomaterials 27, 3995–4002 (2006).

340.        Shustak, G., Domb, A. J. & Mandler, D. n-Alkanoic acid monolayers on 316L stainless steel promote the adhesion of electropolymerized polypyrrole films. Langmuir 22, 5237–5240 (2006).

341.        Mizrahi, B., Shapira, L., Domb, A. J. & Houri-Haddad, Y. Citrus oil and MgCl2 as antibacterial and anti-inflammatory agents. J. Periodontol. 77, 963–968 (2006).

342.        Slivniak, R., Ezra, A. & Domb, A. J. Hydrolytic degradation and drug release of ricinoleic acid-lactic acid copolyesters. Pharm. Res. 23, 1306–1312 (2006).

343.        Sokolsky-Papkov, M., Domb, A. J. & Golenser, J. Impact of aldehyde content on amphotericin B - Dextran imine conjugate toxicity. Biomacromolecules 7, 1529–1535 (2006).

344.        Eliyahu, H., Joseph, A., Azzam, T., Barenholz, Y. & Domb, A. J. Dextran-spermine-based polyplexes - Evaluation of transgene expression and of local and systemic toxicity in mice. Biomaterials 27, 1636–1645 (2006).

345.        Eliyahu, H., Siani, S., Azzam, T., Domb, A. J. & Barenholz, Y. Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates. Biomaterials 27, 1646–1655 (2006).

346.        Eljarrat-Binstock, E. & Domb, A. J. Iontophoresis: A non-invasive ocular drug delivery. J. Control. Release 110, 479–489 (2006).

347.        Golenser, J. & Domb, A. New formulations and derivatives of Amphotericin B for treatment of leishmaniasis. Mini-Reviews Med. Chem. 6, 153–162 (2006).

348.        Golenser, J. et al. Iron chelators: Correlation between effects on Plasmodium spp. and immune functions. J. Parasitol. 92, 170–177 (2006).

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350.        Raiskup-Wolf, F., Eljarrat-Binstock, E., Rehak, M., Domb, A. & Frucht-Pery, J. Delivery of the gentamicin to the eye via iontophoresis . Ces. a Slov. Oftalmol. 62, 175–181 (2006).

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353.        Ben-Shabat, S., Elmalak, O., Nyska, A. & Domb, A. J. Synthesis and characterization of biodegradable copolyesters and copolyanhydrides prepared from fumaric and succinic acid trimers and oligomers. Isr. J. Chem. 45, 411–420 (2005).

354.        Shikanov, A., Kumar, N. & Domb, A. J. Biodegradable polymers: An update. Isr. J. Chem. 45, 393–399 (2005).

355.        Bishara, A. & Domb, A. J. PLA stereocomplexes for controlled release of somatostatin analogue. J. Control. Release 107, 474–483 (2005).

356.        Eljarrat-Binstock, E., Raiskup, F., Frucht-Pery, J. & Domb, A. J. Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel. J. Control. Release 106, 386–390 (2005).

357.        Slager, J., Brizzolara, D., Cantow, H. J. & Domb, A. J. Crystallization and stereocomplexation governed self-assembling of poly(lactide)-b-poly(ethylene glycol) to mesoscale structures. Polym. Adv. Technol. 16, 667–674 (2005).

358.        Kricheldorf, H. R., Rost, S., Wutz, C. & Domb, A. Stereocomplexes of A-B-A triblock copolymers based on poly(L-lactide) and poly(D-lactide) A blocks. Macromolecules 38, 7018–7025 (2005).

359.        Tyr’yan, Y. I., Gorenbein, P. & Domb, A. J. Analysis of the kinetics and current efficiency of pyrrole galvanostatic electropolymerization. J. Appl. Polym. Sci. 97, 1167–1169 (2005).

360.        Layre, A.-M. et al. Nanoencapsulation of a crystalline drug. Int. J. Pharm. 298, 323–327 (2005).

361.        Eljarrat-Binstock, E., Raiskup, F., Frucht-Pery, J. & Domb, A. J. Hydrogel iontophoresis for gentamicin administration to the rabbit eye. in Ophtalmic Technologies XV (eds. F., M., P.G., S., A., H., B.E., S. & M., B.) vol. 5688 234–239 (2005).

362.        Krasko, M. Y. & Domb, A. J. Hydrolytic degradation of ricinoleic-sebacic-ester-anhydride copolymers. Biomacromolecules 6, 1877–1884 (2005).

363.        Slivniak, R. & Domb, A. J. Lactic acid and ricinoleic acid based copolyesters. Macromolecules 38, 5545–5553 (2005).

364.        Slivniak, R., Langer, R. & Domb, A. J. Lactic and ricinoleic acid based copolyesters stereocomplexation. Macromolecules 38, 5634–5639 (2005).

365.        Shikanov, A., Ezra, A. & Domb, A. J. Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel - Effect of additives. J. Control. Release 105, 52–67 (2005).

366.        Bishara, A., Kricheldorf, H. R. & Domb, A. J. Stereocomplexes of triblock poly(lactide- PEG2000-lactide) as carrier of drugs. Macromol. Symp. 225, 17–30 (2005).

367.        Slivniak, R. & Domb, A. J. Macrolactones and polyesters from ricinoleic acid. Biomacromolecules 6, 1679–1688 (2005).

368.        Falk, R. et al. Induction of interleukin-1β, tumour necrosis factor-α and apoptosis in mouse organs by amphotericin B is neutralized by conjugation with arabinogalactan. J. Antimicrob. Chemother. 55, 713–720 (2005).

369.        Kumar, N., Bentolila, A. & Domb, A. J. Structure and biological activity of heparinoid. Mini-Reviews Med. Chem. 5, 441–447 (2005).

370.        Jain, J. P., Modi, S., Domb, A. J. & Kumar, N. Role of polyanhydrides as localized drug carriers. J. Control. Release 103, 541–563 (2005).

371.        Yudovin-Farber, I., Azzam, T., Metzer, E., Taraboulos, A. & Domb, A. J. Cationic polysaccharides as antiprion agents. J. Med. Chem. 48, 1414–1420 (2005).

372.        Eliyahu, H. et al. Novel dextran - Spermine conjugates as transfecting agents: Comparing water-soluble and micellar polymers. Gene Ther. 12, 494–503 (2005).

373.        Ehrenfreund-Kleinman, T. et al. The effect of amphotericin B derivatives on Leishmania and immune functions. J. Parasitol. 91, 158–163 (2005).

374.        Vaisman, B., Shikanov, A. & Domb, A. J. Normal phase high performance liquid chromatography for determination of paclitaxel incorporated in a lipophilic polymer matrix. J. Chromatogr. A 1064, 85–95 (2005).

375.        Ehrenfreund-Kleinman, T., Golenser, J. & Domb, A. J. Polysaccharide scaffolds for tissue engineering. in Scaffolding in Tissue Engineering 27–44 (CRC Press, 2005).

376.        Yudovin-Farber, I., Yanay, C., Azzam, T., Linial, M. & Domb, A. J. Quaternary ammonium polysaccharides for gene delivery. Bioconjug. Chem. 16, 1196–1203 (2005).

377.        Eliyahu, H., Barenholz, Y. & Domb, A. J. Polymers for DNA delivery. Molecules 10, 34–64 (2005).

378.        Kumar, M. N. V. R., Muzzarelli, R. A. A., Muzzarelli, C., Sashiwa, H. & Domb, A. J. Chitosan chemistry and pharmaceutical perspectives. Chem. Rev. 104, 6017–6084 (2004).

379.        Slager, J. & Domb, A. J. Hetero-stereocomplexes of D-poly(lactic acid) and the LHRH analogue leuprolide. Application in controlled release. Eur. J. Pharm. Biopharm. 58, 461–469 (2004).

380.        Falk, R., Grunwald, J., Hoffman, A., Domb, A. J. & Polacheck, I. Distribution of amphotericin B-arabinogalactan conjugate in mouse tissue and its therapeutic efficacy against murine aspergillosis. Antimicrob. Agents Chemother. 48, 3606–3609 (2004).

381.        Shustak, G., Domb, A. J. & Mandler, D. Preparation and characterization of n-alkanoic acid self-assembled monolayers adsorbed on 316L stainless steel. Langmuir 20, 7499–7506 (2004).

382.        Pawar, R., Ben-Ari, A. & Domb, A. J. Protein and peptide parenteral controlled delivery. Expert Opin. Biol. Ther. 4, 1203–1212 (2004).

383.        Eljarrat-Binstock, E., Raiskup, F., Stepensky, D., Domb, A. J. & Frucht-Pery, J. Delivery of gentamicin to the rabbit eye by drug-loaded hydrogel iontophoresis. Investig. Ophthalmol. Vis. Sci. 45, 2543–2548 (2004).

384.        Eljarrat-Binstock, E., Raiskup, F., Frucht-Pery, J. & Domb, A. J. Hydrogel probe for iontophoresis drug delivery to the eye. J. Biomater. Sci. Polym. Ed. 15, 397–413 (2004).

385.        Azzam, T., Eliyahu, H., Makovitzki, A., Linial, M. & Domb, A. J. Hydrophobized dextran-spermine conjugate as potential vector for in vitro gene transfection. J. Control. Release 96, 309–323 (2004).

386.        Shikanov, A., Vaisman, B., Krasko, M. Y., Nyska, A. & Domb, A. J. Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel: In vitro release and in vivo toxicity. J. Biomed. Mater. Res. - Part A 69, 47–54 (2004).

387.        Weiss, Z., Mandler, D., Shustak, G. & Domb, A. J. Pyrrole Derivatives for Electrochemical Coating of Metallic Medical Devices. J. Polym. Sci. Part A Polym. Chem. 42, 1658–1667 (2004).

388.        Pawar, R., Shikanov, A., Vaisman, B. & Domb, A. J. Intravenous and regional paclitaxel formulations. Curr. Med. Chem. 11, 397–402 (2004).

389.        Domb, A. J., Ezra, A. & Mizrahi, B. Lipospheres for vaccine delivery. in Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications 87–99 (CRC Press, 2004). doi:10.1201/9780203505281.

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391.        Azzam, T. & Domb, A. J. Cationic polysaccharides for gene delivery. in Polymeric Gene Delivery: Principles and Applications 279–299 (CRC Press, 2004). doi:10.1201/9780203500477.

392.        Azzam, T. & Domb, A. J. Current developments in gene transfection agents. Curr. Drug Deliv. 1, 165–193 (2004).

393.        Bekerman, T., Golenser, J. & Domb, A. Cyclosporin Nanoparticulate Lipospheres for Oral Administration. J. Pharm. Sci. 93, 1264–1270 (2004).

394.        Wolnerman, J. S. et al. A new gel for topical use in treating severe periodontal disease--clinical observations. Refuat ha-peh eha-shinayim (1993) 21, 72-77,99 (2004).

395.        Le Bon, B. et al. AMD3100 Conjugates as Components of Targeted Nonviral Gene Delivery Systems: Synthesis and in Vitro Transfection Efficiency of CXCR4-Expressing Cells. Bioconjug. Chem. 15, 413–423 (2004).

396.        Ehrenfreund-Kleinman, T., Golenser, J. & Domb, A. J. Conjugation of amino-containing drugs to polysaccharides by tosylation: Amphotericin B-arabinogalactan conjugates. Biomaterials 25, 3049–3057 (2004).

397.        Mizrahi, B., Golenser, J., Wolnerman, J. S. & Domb, A. J. Adhesive tablet effective for treating canker sores in humans. J. Pharm. Sci. 93, 2927–2935 (2004).

398.        Frucht-Pery, J. et al. Iontophoresis-gentamicin delivery into the rabbit cornea, using a hydrogel delivery probe. Exp. Eye Res. 78, 745–749 (2004).

399.        Hosseinkhani, H., Azzam, T., Tabata, Y. & Domb, A. J. Dextran-spermine polycation: An efficient nonviral vector for in vitro and in vivo gene transfection. Gene Ther. 11, 194–203 (2004).

400.        Golenser, J., Domb, A., Leshem, B., Kremsner, P. & Luty, A. Iron chelators as drugs against malaria pose a potential risk. Redox Rep. 8, 268–271 (2003).

401.        Ben-Shabat, S., Abuganima, E., Raziel, A. & Domb, A. J. Biodegradable polycaprolactone-polyanhydrides blends. J. Polym. Sci. Part A Polym. Chem. 41, 3781–3787 (2003).

402.        Ehrenfreund-Kleinman, T., Domb, A. J. & Golenser, J. Polysaccharide Scaffolds Prepared by Crosslinking of Polysaccharides with Chitosan or Proteins for Cell Growth. J. Bioact. Compat. Polym. 18, 323–338 (2003).

403.        Slager, J. & Domb, A. J. Heterostereocomplexes prepared from D-PLA and L-PLA and leuprolide. II. Release of leuprolide. Biomacromolecules 4, 1316–1320 (2003).

404.        Slager, J. & Domb, A. J. Heterostereocomplexes prepared from D-poly(lactide) and leuprolide. I. Characterization. Biomacromolecules 4, 1308–1315 (2003).

405.        Pradilla, G., Azzam, T., Wang, P. P., Domb, A. J. & Brem, H. Gene therapy for malignant brain tumors. Expert Rev. Neurother. 3, 685–701 (2003).

406.        Kricheldorf, H. R., Fechner, B., Shikanov, A. & Domb, A. Polylactones 57. Biodegradable networks based on A - B - A triblock segments containing poly(ethylene glycol)s - Syntheses and drug release properties. Biomacromolecules 4, 950–955 (2003).

407.        Slager, J., Cohen, Y., Khalfin, R., Talmon, Y. & Domb, A. J. Peptides form stereoselective complexes with chiral polymers. Macromolecules 36, 2999–3000 (2003).

408.        Heller, J. & Domb, A. J. Recent developments with biodegradable polymers. Adv. Drug Deliv. Rev. 55, 445–446 (2003).

409.        Slager, J. & Domb, A. J. Biopolymer stereocomplexes. Adv. Drug Deliv. Rev. 55, 549–583 (2003).

410.        Krasko, M. Y., Shikanov, A., Ezra, A. & Domb, A. J. Poly(ester anhydride)s prepared by the insertion of ricinoleic acid into poly(sebacic acid). J. Polym. Sci. Part A Polym. Chem. 41, 1059–1069 (2003).

411.        Shaaya, O., Magora, A., Sheskin, T., Kumar, N. & Domb, A. J. Anhydride prodrugs for nonsteroidal anti-inflammatory drugs. Pharm. Res. 20, 205–211 (2003).

412.        Krasko, M. Y., Ezra, A. & Domb, A. J. Lithocholic-acid-containing poly (ester-anhydride)s. Polym. Adv. Technol. 14, 832–838 (2003).

413.        Azzam, T., Eliyahu, H., Makovitzki, A. & Domb, A. J. Dextran-spermine conjugate: An efficient vector for gene delivery. Macromol. Symp. 195, 247–262 (2003).

414.        Azzam, T. et al. Cationic polysaccharides for gene delivery. Macromolecules 35, 9947–9953 (2002).

415.        Domb, A. J. & Slager, J. Sixth International Symposium on Polymers for Advanced Technologies (PAT-2001). Polym. News 27, 138–142 (2002).

416.        Ehrenfreund-Kleinman, T. et al. Synthesis and biodegradation of arabinogalactan sponges prepared by reductive amination. Biomaterials 23, 4621–4631 (2002).

417.        Hazra, B. et al. Inhibitory activity of diospyrin derivatives against Leishmania major parasites in vitro. Indian J. Pharmacol. 34, 422–427 (2002).

418.        Kumar, N., Langer, R. S. & Domb, A. J. Polyanhydrides: An overview. Adv. Drug Deliv. Rev. 54, 889–910 (2002).

419.        Heller, J., Domb, A. J. & Kumar, N. Polyanhydrides and poly(ortho esters). Adv. Drug Deliv. Rev. 54, 887–888 (2002).

420.        Slivniak, R. & Domb, A. J. Stereocomplexes of enantiomeric lactic acid and sebacic acid ester-anhydride triblock copolymers. Biomacromolecules 3, 754–760 (2002).

421.        Slager, J. & Domb, A. J. Stereocomplexes based on poly(lactic acid) and insulin: Formulation and release studies. Biomaterials 23, 4389–4396 (2002).

422.        Kumar, N. et al. Analysis of fatty acid anhydrides and polyanhydrides. Anal. Chim. Acta 465, 257–272 (2002).

423.        Azzam, T. et al. Polysaccharide-oligoamine based conjugates for gene delivery. J. Med. Chem. 45, 1817–1824 (2002).

424.        Ehrenfreund-Kleinman, T. et al. Synthesis and characterization of novel water soluble amphotericin B-arabinogalactan conjugates. Biomaterials 23, 1327–1335 (2002).

425.        Rasiel, A., Sheskin, T., Bergelson, L. & Domb, A. J. Phospholipid coated poly(lactic acid) microspheres for the delivery of LHRH analogues. Polym. Adv. Technol. 13, 127–136 (2002).

426.        Azzam, T. et al. Cationic polysaccharides as vectors for gene delivery. in 224th ACS National Meeting vol. 43 671–672 (Polymer Preprints ACS, 2002).

427.        Ehrenfreund-Kleinman, T. et al. Arabinogalactan based sponges for tissue engineering. in 224th ACS National Meeting vol. 43 730–731 (Polymer Preprints ACS, 2002).

428.        Eliyahu, N., Servel, N., Domb, A. J. & Barenholz, Y. Magnetic properties of iron-containing particles in a quartz matrix after mechanochemical processing. Inorg. Mater. 38, 132–136 (2002).

429.        Krasko, M. Y., Shikanov, A., Kumar, N. & Domb, A. J. Polyanhydrides with hydrophobic terminals. Polym. Adv. Technol. 13, 960–968 (2002).

430.        Kumar, N., Azzam, T. & Domb, A. J. Molecular mass distribution of polycations and dextrans by high-performance size exclusion chromatography. Polym. Adv. Technol. 13, 1071–1077 (2002).

431.        Azzam, T., Peppas, N. A., Slomkowski, S. & Domb, A. J. ‘Length and breadth’ Polyrotaxane structures - A new concept in three-dimensional polymeric systems. Polym. Adv. Technol. 13, 788–797 (2002).

432.        Eliyahu, N., Servel, N., Domb, A. J. & Barenholz, Y. Lipoplex-induced hemagglutination: Potential involvement in intravenous gene delivery. Gene Ther. 9, 850–858 (2002).

433.        Ravi Kumar, M. N. V, Kumar, N., Domb, A. J. & Arora, M. Pharmaceutical polymeric controlled drug delivery systems. Adv. Polym. Sci. 160, 45–117 (2002).

434.        Kumar, N., Ravikumar, M. N. V & Domb, A. J. Biodegradable block copolymers. Adv. Drug Deliv. Rev. 53, 23–44 (2001).

435.        Pines, M. et al. Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone. Biochem. Pharmacol. 62, 1221–1227 (2001).

436.        Teomim, D., Mäder, K., Bentolila, A., Magora, A. & Domb, A. J. γ-irradiation stability of saturated and unsaturated aliphatic polyanhydrides-ricinoleic acid based polymers. Biomacromolecules 2, 1015–1022 (2001).

437.        Teomim, D. & Domb, A. J. Nonlinear fatty acid terminated polyanhydrides. Biomacromolecules 2, 37–44 (2001).

438.        Slager, J., Gladnikoff, M. & Domb, A. J. Stereocomplexes, based on biodegradable polymers and bioactive macromolecules. Macromol. Symp. 175, 105–116 (2001).

439.        Bentolila, A., Vlodavsky, I., Haloun, C. & Domb, A. J. Synthesis and heparin-like biological activity of amino acid-based polymers. Polym. Adv. Technol. 11, 377–387 (2000).

440.        Bledi, Y., Domb, A. J. & Linial, M. Culturing neuronal cells on surfaces coated by a novel polyethyleneimine-based polymer. Brain Res. Protoc. 5, 282–289 (2000).

441.        Bentolila, A. et al. Poly(n-acryl amino acids): A new class of biologically active polyanions. J. Med. Chem. 43, 2591–2600 (2000).

442.        Byrd, K. E., Yang, L., Yancey, K. W., Teomim, D. & Domb, A. J. Increased in vivo levels of neurotransmitters to trigeminal motoneurons: Effects on craniofacial bone and TMJ. Anat. Rec. 258, 369–383 (2000).

443.        Shikani, A. H. & Domb, A. J. Polymer chemotherapy for head and neck cancer. Laryngoscope 110, 907–917 (2000).

444.        Teomim, D. & Domb, A. J. Fatty acid terminated polyanhydrides. J. Polym. Sci. Part A Polym. Chem. 37, 3337–3344 (1999).

445.        Domb, A. Gliadel--a preparation for the supplementary treatment of brain cancer. Harefuah 137, 127–131 (1999).

446.        Teomim, D. et al. Perivascular delivery of heparin for the reduction of smooth muscle cell proliferation after endothelial injury. J. Control. Release 60, 129–142 (1999).

447.        Domb, A. J., Israel, Z. H., Elmalak, O., Teomim, D. & Bentolila, A. Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors. Pharm. Res. 16, 762–765 (1999).

448.        Teomim, D., Nyska, A. & Domb, A. J. Ricinoleic acid-based biopolymers. J. Biomed. Mater. Res. 45, 258–267 (1999).

449.        Golenser, J., Frankenburg, S., Ehrenfreund, T. & Domb, A. J. Efficacious treatment of experimental leishmaniasis with amphotericin B- arabinogalactan water-soluble derivatives. Antimicrob. Agents Chemother. 43, 2209–2214 (1999).

450.        Falk, R., Domb, A. J. & Polacheck, I. A novel injectable water-soluble amphotericin B-arabinogalactan conjugate. Antimicrob. Agents Chemother. 43, 1975–1981 (1999).

451.        Teomim, D. & Domb, A. J. Synthesis and characterization of fatty acid terminated poly(sebacic anhydride). Proc. Control. Release Soc. 699–700 (1999).

452.        Leadley, S. R. et al. Analysis of the surface chemical structure of copolymers of poly(sebacic anhydride) with ricinoleic acid maleate using XPS and ToF-SIMS. Macromolecules 31, 8957–8965 (1998).

453.        Kubek, M. J., Liang, D., Byrd, K. E. & Domb, A. J. Prolonged seizure suppression by a single implantable polymeric-TRH microdisk preparation. Brain Res. 809, 189–197 (1998).

454.        Masters, D. B. & Domb, A. J. Liposphere local anesthetic timed-release for perineural site application. Pharm. Res. 15, 1038–1045 (1998).

455.        Chen, X. et al. Chemical and morphological analysis of surface enrichment in a biodegradable polymer blend by phase-detection imaging atomic force microscopy. Macromolecules 31, 2278–2283 (1998).

456.        Domb, A. J., Bentolila, A. & Teomin, D. Biopolymers as drug carriers and bioactive macromolecules. Acta Polym. 49, 526–533 (1998).

457.        Israel, Z. H. & Domb, A. J. Polymers in gene therapy: Antisense delivery systems. Polym. Adv. Technol. 9, 799–805 (1998).

458.        Teomim, D., Mader, K. & Domb, A. J. Stability of ricinoleic acid based polymers to gamma sterilization. Proc. Control. Release Soc. 701–702 (1998).

459.        Mäder, K., Crémmilleux, Y., Domb, A. J., Dunn, J. F. & Swartz, H. M. In vitro/in vivo comparison of drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides - A noninvasive approach by the combined use of electron paramagnetic resonance spectroscopy and nuclear magnetic resonance imaging. Pharm. Res. 14, 820–826 (1997).

460.        Peracchia, M. T. et al. PEG-coated nanospheres from amphiphilic diblock and multiblock copolymers: Investigation of their drug encapsulation and release characteristics. J. Control. Release 46, 223–231 (1997).

461.        Golenser, J. et al. The treatment of animal models of malaria with iron chelators by use of a novel polymeric device for slow drug release. J. Pharmacol. Exp. Ther. 281, 1127–1135 (1997).

462.        Orloff, L. A., Domb, A. J., Teomim, D., Fishbein, I. & Golomb, G. Biodegradable implant strategies for inhibition of restenosis. Adv. Drug Deliv. Rev. 24, 3–9 (1997).

463.        Mäder, K., Nitschke, S., Stösser, R., Borchert, H.-H. & Domb, A. Non-destructive and localized assessment of acidic microenvironments inside biodegradable polyanhydrides by spectral spatial electron paramagnetic resonance imaging. Polymer (Guildf). 38, 4785–4794 (1997).

464.        Byrd, K. E. et al. Craniofacial and TMJ effects after glutamate and TRH microsphere implantation in proximity to trigeminal motoneurons of growing rats. J. Dent. Res. 76, 1437–1452 (1997).

465.        Hrkach, J. S., Peracchia, M. T., Domb, A., Lotan, N. & Langer, R. Nanotechnology for biomaterials engineering: Structural characterization of amphiphilic polymeric nanoparticles by 1H NMR spectroscopy. Biomaterials 18, 27–30 (1997).

466.        Mader, K., Nitschke, S., Borchert, H. H., Stosser, R. & Domb, A. Noninvasive monitoring of pH-gradients and free radical distributions in polyanhydrides by Spectral-Spatial-EPRI. Proc. Control. Release Soc. 109–110 (1997).

467.        Teomim, D. & Domb, A. J. Ricinoleic acid based biopolymers. Proc. Control. Release Soc. 539–540 (1997).

468.        McGurk, S. L. et al. Rapid screening of biodegradable polymers by AFM and SPR. Proc. Control. Release Soc. 947–948 (1997).

469.        Bentolila, A. & Domb, A. J. Biologically active poly(N-acryl amino acids). Proc. Control. Release Soc. 541–542 (1997).

470.        Mäder, K. et al. Noninvasive in Vivo Monitoring of Drug Release and Polymer Erosion from Biodegradable Polymers by EPR Spectroscopy and NMR Imaging. J. Pharm. Sci. 86, 126–134 (1997).

471.        Gref, R. et al. Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration. Pharm. Biotechnol. 10, 167–198 (1997).

472.        Olivi, A. et al. Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat. Cancer Chemother. Pharmacol. 39, 90–96 (1996).

473.        Byrd, K. E., Dowlinq, J. R., Sukav, M. J., Thorne, G. D. & Domb, A. J. Effects of trh implants in proximity to trigeminal motoneurons upon the craniofacial complex. FASEB J. 10, (1996).

474.        Mäder, K., Domb, A. & Swartz, H. M. Gamma-sterilization-induced radicals in biodegradable drug delivery systems. Proc. 1995 4th Int. Symp. ESR Dosim. Appl. 47, 1669–1674 (1996).

475.        Shikani, A. H., Clair, M. S. & Domb, A. Polymer-iodine inactivation of the human immunodeficiency virus. J. Am. Coll. Surg. 183, 195–200 (1996).

476.        Davies, M. C. et al. Surface analysis of biodegradable polymer blends of poly(sebacic anhydride) and poly(DL-lactic acid). Macromolecules 29, 2205–2212 (1996).

477.        Weiss, A. M., Khayutin, L., Bentolila, A. & Domb, A. Noninvasive optical characterization OP hydrogels. Macromol. Symp. 109, 67–75 (1996).

478.        Brizzolara, D., Cantow, H. J., Mülhaupt, R. & Domb, A. J. Novel materials through stereocomplexation. J. Comput. Mater. Des. 3, 341–350 (1996).

479.        Domb, A. J., Linden, G., Polacheck, I. & Benita, S. Nystatin-dextran conjugates: Synthesis and characterization. J. Polym. Sci. Part A Polym. Chem. 34, 1229–1236 (1996).

480.        Domb, A. J., Manor, N. & Elmalak, O. Biodegradable bone cement compositions based on acrylate and epoxide terminated poly(propylene fumarate) oligomers and calcium salt compositions. Biomaterials 17, 411–417 (1996).

481.        Elmalak, O. & Domb, A. J. Synthesis and reactions of bromoalkylcarbonates. Proc. Control. Release Soc. 753–754 (1996).

482.        Brizzolara, D., Cantow, H.-J., Diederichs, K., Keller, E. & Domb, A. J. Mechanism of the stereocomplex formation between enantiomeric poly(lactide)s. Macromolecules 29, 191–197 (1996).

483.        Domb, A. J. Long acting injectable oxytetracycline-liposphere formulations. Int. J. Pharm. 124, 271–278 (1995).

484.        Crämer, K., Wawkuschewski, A., Domb, A., Cantow, H.-J. & Magonov, S. N. Atomic force microscopy of polyethylene and poly-(d-lactide) single crystals. Polym. Bull. 35, 457–464 (1995).

485.        Shakesheff, K. M. et al. Relating the Phase Morphology of a Biodegradable Polymer Blend to Erosion Kinetics Using Simultaneous in Situ Atomic Force Microscopy and Surface Plasmon Resonance Analysis. Langmuir 11, 3921–3927 (1995).

486.        Shakesheff, K. M. et al. In Situ Atomic Force Microscopy Visualization of the Degradation of Melt-Crystallized Poly(sebacic anhydride). Macromolecules 28, 1108–1114 (1995).

487.        Domb, A. J. & Nudelman, R. Biodegradable polymers derived from natural fatty acids. J. Polym. Sci. Part A Polym. Chem. 33, 717–725 (1995).

488.        Gref, R. et al. The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres. Adv. Drug Deliv. Rev. 16, 215–233 (1995).

489.        Domb, A. J. Polymericcarriers for regional drug therapy. Mol. Med. Today 1, 134–139 (1995).

490.        Domb, A. J., Marlinsky, A., Maniar, M. & Teomim, L. Insect repellent formulations of N,N-diethyl-m-toluamide (deet) in a liposphere system: efficacy and skin uptake. J. Am. Mosq. Control Assoc. 11, 29–34 (1995).

491.        Domb, A. J. & Nudelman, R. In vivo and in vitro elimination of aliphatic polyanhydrides. Biomaterials 16, 319–323 (1995).

492.        Domb, A. J., Manor, N. & Elmalak, O. Biodegradable composites based on epoxide and acrylate terminated poly(propylene fumarate) oligomers and calcium salt compositions. Proc. Control. Release Soc. 782–783 (1995).

493.        Domb, A. J. et al. Excretion of a radiolabelled anticancer biodegradable polymeric implant from the rabbit brain. Biomaterials 16, 1069–1072 (1995).

494.        Shakesheff, K. M. et al. The characterization of polymer biodegradation by in situ atomic force microscopy and surface plasmon resonance analysis. Proc. Control. Release Soc. 384–385 (1995).

495.        Mader, K., Bacic, G., Domb, A., Langer, R. & Swartz, H. M. Noninvasive in vivo characterization of biodegradable polymers by EPR spectroscopy and NMR imaging. Proc. Control. Release Soc. 77–78 (1995).

496.        Mader, K., Bacic, G., Domb, A. & Swartz, H. M. Characterization of microstructures in drug delivery systems by EPR spectroscopy. Proc. Control. Release Soc. 780–781 (1995).

497.        Domb, A. J., Linden, G., Polacheck, I. & Benita, S. Synthesis and biological activity of nystatin-dextran conjugates. Proc. Control. Release Soc. 744–745 (1995).

498.        Orloff, L. A., Glenn, M. G., Domb, A. J. & Esclamado, R. A. Prevention of venous thrombosis in microvascular surgery by transmural release of heparin from a polyanhydride polymer. Surgery 117, 554–559 (1995).

499.        Judy, K. D. et al. Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. J. Neurosurg. 82, 481–486 (1995).

500.        Peracchia, M. T., Gref, R., Minamitake, Y., Domb, A. & Langer, R. PEG-coated nanospheres for intravenous drug delivery and targeting. Proc. Control. Release Soc. 513–514 (1994).

501.        Shakesheff, K. M. et al. In Situ Atomic Force Microscopy Imaging of Polymer Degradation in an Aqueous Environment. Langmuir 10, 4417–4419 (1994).

502.        Domb, A. J. Quantitative analysis of mixtures of symmetric and mixed anhydrides. J. Chromatogr. A 673, 31–35 (1994).

503.        Domb, A. J. & Ringel, I. Polymeric Drug Carrier Systems in the Brain. Methods in Neurosciences vol. 21 169–183 (1994).

504.        Shieh, L. et al. Erosion of a new family of biodegradable polyanhydrides. J. Biomed. Mater. Res. 28, 1465–1475 (1994).

505.        Domb, A. J. & Wartenfeld, R. Methotrexate polymer implant for the treatment of head and neck cancer. Polym. Adv. Technol. 5, 577–581 (1994).

506.        Walter, K. A. et al. Interstitial Taxol Delivered from a Biodegradable Polymer Implant against Experimental Malignant Glioma1. Cancer Res. 54, 2207–2212 (1994).

507.        Maniar, M., Domb, A., Haffer, A. & Shah, J. Controlled release of a local anesthetic from fatty acid dimer based polyanhydride. J. Control. Release 30, 233–239 (1994).

508.        Shieh, L., Tamada, J., Tabata, Y., Domb, A. & Langer, R. Drug release from a new family of biodegradable polyanhydrides. J. Control. Release 29, 73–82 (1994).

509.        Domb, A. J. et al. Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain. Biomaterials 15, 681–688 (1994).

510.        Domb, A. J., Turovsky, L. & Nudelman, R. Chemical Interactions Between Drugs Containing Reactive Amines with Hydrolyzable Insoluble Biopolymers in Aqueous Solutions. Pharm. Res. An Off. J. Am. Assoc. Pharm. Sci. 11, 865–868 (1994).

511.        Shakesheff, K. M. et al. Visualizing the degradation of polymer surfaces with an atomic force microscope. Proc. Control. Release Soc. 618–619 (1994).

512.        Tabata, Y., Domb, A. & Langer, R. Injectable polyanhydride granules provide controlled release of water‐soluble drugs with a reduced initial burst. J. Pharm. Sci. 83, 5–11 (1994).

513.        Domb, A. J., Turovsky, L. & Nudelman, R. Interactions between drugs and hydrolyzable biopolymers in aqueous solutions. Proc. Control. Release Soc. 517–518 (1994).

514.        Shikani, A. H., Eisele, D. W. & Domb, A. J. Polymer Delivery of Chemotherapy for Squamous Cell Carcinoma of the Head and Neck. Arch. Otolaryngol. Neck Surg. 120, 1242–1247 (1994).

515.        Domb, A. J., Amselem, S., Shah, J. & Maniar, M. Polyanhydrides: Synthesis and characterization. Advances in Polymer Science vol. 107 93–141 (1993).

516.        Domb, A. J. Degradable polymer blends. I. Screening of miscible polymers. J. Polym. Sci. Part A Polym. Chem. 31, 1973–1981 (1993).

517.        Domb, A. J. & Maniar, M. Absorbable biopolymers derived from dimer fatty acids. J. Polym. Sci. Part A Polym. Chem. 31, 1275–1285 (1993).

518.        Laurencin, C. T. et al. Bioerodible polyanhydrides for antibiotic drug delivery: In vivo osteomyelitis treatment in a rat model system. J. Orthop. Res. 11, 256–262 (1993).

519.        Shieh, L., Tamada, J., Tabata, Y., Domb, A. & Langer, R. Drug release from a new family of biodegradable polyanhydrides. Proc. Control. Release Soc. 470–471 (1993).

520.        Domb, A. J. Liposphere parenteral delivery system. Proc. Control. Release Soc. 121–122 (1993).

521.        Byrd, K. E., Domb, A. J., Sokoloff, A. J. & Hamilton‐Byrd, E. L. Stimulation of trigeminal motoneurons by in vivo implantation of glutamate‐impregnated microspheres. Polym. Adv. Technol. 3, 337–344 (1992).

522.        Amselem, S., Alving, C. R. & Domb, A. J. Polymeric biodegradable lipospheresTM as vaccine delivery systems. Polym. Adv. Technol. 3, 351–357 (1992).

523.        Buahin, K. G. et al. Controlled release of 4‐hydroperoxycyclophosphamide from the fatty acid dimer‐sebacic acid copolymer. Polym. Adv. Technol. 3, 311–316 (1992).

524.        Domb, A., Maniar, M. & Langer, R. Editorial—absorbable polymers for site‐specific drug delivery. Polym. Adv. Technol. 3, 277 (1992).

525.        Domb, A., Amselem, S., Shah, J. & Maniar, M. Degradable polymers for site‐specific drug delivery. Polym. Adv. Technol. 3, 279–292 (1992).

526.        Domb, A. J. Synthesis and Characterization of Biodegradable Aromatic Anhydride Copolymers. Macromolecules 25, 12–17 (1992).

527.        D’Emanuele, A., Hill, J., Tamada, J. A., Domb, A. J. & Langer, R. Molecular Weight Changes in Polymer Erosion. Pharm. Res. An Off. J. Am. Assoc. Pharm. Sci. 9, 1279–1283 (1992).

528.        Brem, H. et al. Brain biocompatibility of a biodegradable controlled release polymer consisting of anhydride copolymer of fatty acid dimer and sebacic acid. J. Control. Release 19, 325–329 (1992).

529.        Langer, R., Ron, E., Mathiowitz, E., Mathiowitz, G. & Domb, A. NMR Characterization of Erodible Copolymers. Macromolecules 24, 2278–2282 (1991).

530.        Tudor, A. M. et al. The application of Fourier transform Raman spectroscopy to the analysis of poly(anhydride) homo- and co-polymers. Spectrochim. Acta Part A Mol. Spectrosc. 47, 1335–1343 (1991).

531.        Domb, A. J., Mathiowitz, E., Ron, E., Giannos, S. & Langer, R. Polyanhydrides. IV. Unsaturated and crosslinked polyanhydrides. J. Polym. Sci. Part A Polym. Chem. 29, 571–579 (1991).

532.        Davies, M. C. et al. The analysis of the surface chemical structure of biomedical aliphatic polyanhydrides using XPS and ToF‐SIMS. J. Appl. Polym. Sci. 42, 1597–1605 (1991).

533.        Domb, A., Maniar, M., Bogdansky, S. & Chasin, M. Drug delivery to the brain using polymers. Crit. Rev. Ther. Drug Carrier Syst. 8, 1–17 (1991).

534.        Domb, A. J. Synthesis of new biodegradable polymers. in Papers Presented at the Boston, Massachusetts Meeting of ACS 1989 vol. 31 252 (Publ by ACS, 1990).

535.        Maniar, M., Xie, X. & Domb, A. J. Polyanhydrides. V. Branched polyanhydrides. Biomaterials 11, 690–694 (1990).

536.        Tudor, A. M. et al. THE ANALYSIS OF POLY(ANHYDRIDES) AND THEIR DEGRADATION BY NIR/FT RAMAN SPECTROSCOPY. J. Pharm. Pharmacol. 42, 115P (1990).

537.        Domb, A. J. Biodegradable polymers derived from amino acids. Biomaterials 11, 686–689 (1990).

538.        Laurencin, C. et al. Poly(anhydride) administration in high doses in vivo: Studies of biocompatibility and toxicology. J. Biomed. Mater. Res. 24, 1463–1481 (1990).

539.        Lucas, P. A. et al. Ectopic induction of cartilage and bone by water‐soluble proteins from bovine bone using a polyanhydride delivery vehicle. J. Biomed. Mater. Res. 24, 901–911 (1990).

540.        Domb, A. J., Laurencin, C. T., Israeli, O., Gerhart, T. N. & Langer, R. The formation of propylene fumarate oligomers for use in bioerodible bone cement composites. J. Polym. Sci. Part A Polym. Chem. 28, 973–985 (1990).

541.        Davis, M. C., Lynn, R. A. P., Langer, R. & Domb, A. Surface analysis of biodegradable poly(anhydride) copolymers by ToF-SIMS. in Proceedings of the ACS Division of Polymeric Materials: Science and Engineering vol. 62 888 (Publ by ACS, 1990).

542.        Domb, A., Davidson III, G. W. R. & Sanders, L. M. Diffusion of peptides through hydrogel membranes. J. Control. Release 14, 133–144 (1990).

543.        Domb, A. J. & Langer, R. Biodegradable polymers derived from amino acids. in Papers Presented at the Miami Beach, FL Meeting: Polymer Preprints vol. 30 189–190 (Publ by ACS, 1989).

544.        Domb, A. J. & Langer, R. Solid-State and Solution Stability of Poly(anhydrides) and Poly(esters). Macromolecules 22, 2117–2122 (1989).

545.        Domb, A. J., Gallardo, C. F. & Langer, R. Poly (anhydrides). 3. Poly (anhydrides) Based on Aliphatic—Aromatic Diacids. Macromolecules 22, 3200–3204 (1989).

546.        Laurencin, C. et al. Crystallinity of polyanhydride copolymers: theoretical and experimental development. in Papers Presented at the Dallas, Texas Meeting vol. 30 466–467 (Publ by ACS, 1989).

547.        Brem, H. et al. Biocompatibility of a Biodegradable, Controlled-Release Polymer in the Rabbit Brain. Sel. Cancer Ther. 5, 55–65 (1989).

548.        Domb, A. & Langer, R. Polyanhydrides: Stability and novel composition. Makromol. Chemie. Macromol. Symp. 19, 189–200 (1988).

549.        Domb, A. J., Cravalho, E. G. & Langer, R. The synthesis of poly(hydroxamic acid) from poly(acrylamide). J. Polym. Sci. Part A Polym. Chem. 26, 2623–2630 (1988).

550.        Domb, A. J., Ron, E. & Langer, R. Poly (anhydrides). 2. One-Step Polymerization Using Phosgene or Diphosgene as Coupling Agents. Macromolecules 21, 1925–1929 (1988).

551.        Mathiowitz, E., Saltzman, W. M., Domb, A., Dor, P. & Langer, R. Polyanhydride microspheres as drug carriers. II. Microencapsulation by solvent removal. J. Appl. Polym. Sci. 35, 755–774 (1988).

552.        Vacanti, J. P. et al. Selective cell transplantation using bioabsorbable artificial polymers as matrices. J. Pediatr. Surg. 23, 3–9 (1988).

553.        Domb, A. J. & Langer, R. Polyanhydrides. I. Preparation of high molecular weight polyanhydrides. J. Polym. Sci. Part A Polym. Chem. 25, 3373–3386 (1987).

554.        Domb, A. J. & Langer, R. PREPARATION AND STABILITY OF HIGH MW POLYANHYDRIDES. in Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials: Science and Engineering. Symposia Held at the 192nd National Meeting of the American Chemistry Society. vol. 55 746–750 (ACS, 1986).

555.        Marcelis, L. et al. Hyperamylasemia in breast cancer . Presse Med. 15, 761 (1986).

556.        Domb, A. & Avny, Y. Reduction and hydroboration with borane and haloborane complexes of poly(propylene sulfide) grafted on crosslinked polystyrene. J. Appl. Polym. Sci. 30, 3589–3604 (1985).

557.        Domb, A. & Avny, Y. Reduction of Carbonyl Compounds by Cross-Linked Poly(4-vinylpyridine)-Borane in Acidic Media. J. Macromol. Sci. Part A - Chem. 22, 183–201 (1985).

558.        Domb, A. & Avny, Y. Preparation and Hydrolytic Stability of Cross-Linked Poly(4-vinylpryridine)-Borane. J. Macromol. Sci. Part A - Chem. 22, 167–181 (1985).

559.        Domb, A. & Avny, Y. Graft polymerization of propylene sulfide on crosslinked polystyrene. J. Appl. Polym. Sci. 29, 2517–2528 (1984).