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School of Pharmacy : Sasson Shlomo

Researchers

 Last updated Septmber 2023 - School of Pharmacy

List of Publications

1.

Lepechkin-Zilbermintz V, Bareket D, Gonnord V, Steffen A, Morice C, Michaut M, et al. Moderately lipophilic 2-(Het)aryl-6-dithioacetals, 2-phenyl-1,4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators. Bioorganic and Medicinal Chemistry [Internet]. 2023;87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85158908997&doi=10.1016%252fj.bmc.2023.117303&partnerID=40&md5=9d5260bc7c2b536b80c595d22b60d37d

2.

Bianchetti G, Clementi ME, Sampaolese B, Serantoni C, Abeltino A, De Spirito M, et al. Metabolic Imaging and Molecular Biology Reveal the Interplay between Lipid Metabolism and DHA-Induced Modulation of Redox Homeostasis in RPE Cells. Antioxidants [Internet]. 2023;12(2). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149245043&doi=10.3390%252fantiox12020339&partnerID=40&md5=d977366f6b00ae05acd65e4a74c40044

3.

Bianchetti G, Clementi ME, Sampaolese B, Serantoni C, Abeltino A, De Spirito M, et al. Investigation of DHA-Induced Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells through the Combination of Metabolic Imaging and Molecular Biology. Antioxidants [Internet]. 2022;11(6). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130732626&doi=10.3390%252fantiox11061072&partnerID=40&md5=df5756c594dcafe37bd887fde79163a3

4.

Bianchetti G, Azoulay-Ginsburg S, Keshet-Levy NY, Malka A, Zilber S, Korshin EE, et al. Investigation of the membrane fluidity regulation of fatty acid intracellular distribution by fluorescence lifetime imaging of novel polarity sensitive fluorescent derivatives. International Journal of Molecular Sciences [Internet]. 2021;22(6):1–17. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102654874&doi=10.3390%252fijms22063106&partnerID=40&md5=c2060093694937b854f080aca52bab4a

5.

Daniel B, Livne A, Cohen G, Kahremany S, Sasson S. Endothelial Cell-Derived Triosephosphate Isomerase Attenuates Insulin Secretion from Pancreatic Beta Cells of Male Rats. Endocrinology (United States) [Internet]. 2021;162(3). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100125870&doi=10.1210%252fendocr%252fbqaa234&partnerID=40&md5=99b0dd8baddbde8e08488b5d99133cb2

6.

Robinson EL, da Costa Gomes CP, Potočnjak I, Hellemans J, Betsou F, de Gonzalo-Calvo D, et al. A year in the life of the EU-CardioRNA COST action: CA17129 catalysing transcriptomics research in cardiovascular disease. Non-coding RNA [Internet]. 2020;6(2). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086089216&doi=10.3390%252fNCRNA6020017&partnerID=40&md5=28b18f4c01dd8f05e8a1704cefbbe268

7.

Maulucci G, Cohen O, Daniel B, Ferreri C, Sasson S. The combination of whole cell lipidomics analysis and single cell confocal imaging of fluidity and micropolarity provides insight into stress-induced lipid turnover in subcellular organelles of pancreatic beta cells. Molecules [Internet]. 2019;24(20). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073635552&doi=10.3390%252fmolecules24203742&partnerID=40&md5=928f23846f13cc94183df0f1c6e9846e

8.

Parchem K, Sasson S, Ferreri C, Bartoszek A. Qualitative analysis of phospholipids and their oxidised derivatives–used techniques and examples of their applications related to lipidomic research and food analysis. Free Radical Research [Internet]. 2019;53(sup1):1068–100. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071984657&doi=10.1080%252f10715762.2019.1657573&partnerID=40&md5=4ee99c2117bc4d1584d28b3382de8a6d

9.

Cordelli E, Merone M, Di Giacinto F, Daniel B, Maulucciy G, Sasson S, et al. Early experiences in 4D quantitative analysis of insulin granules in living beta-cells. In: Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 [Internet]. 2019. p. 2009–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062519261&doi=10.1109%252fBIBM.2018.8621293&partnerID=40&md5=89bec2ca8018bdd92bf835ad36a5d6bb

10.

Uchida K, Shibata T, Toyokuni S, Daniel B, Zarkovic K, Zarkovic N, et al. Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo. Free Radical Biology and Medicine [Internet]. 2018;124:12–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047791506&doi=10.1016%252fj.freeradbiomed.2018.05.079&partnerID=40&md5=04db641d714b825dc7228e5c55d01ff8

11.

Maulucci G, Di Giacinto F, De Angelis C, Cohen O, Daniel B, Ferreri C, et al. Real time quantitative analysis of lipid storage and lipolysis pathways by confocal spectral imaging of intracellular micropolarity. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids [Internet]. 2018;1863(7):783–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046029118&doi=10.1016%252fj.bbalip.2018.04.004&partnerID=40&md5=af9a58d7dff97c2d3f1598d2412c8ba2

12.

Rozentul N, Avrahami Y, Shubely M, Levy L, Munder A, Cohen G, et al. A Novel Phenylchromane Derivative Increases the Rate of Glucose Uptake in L6 Myotubes and Augments Insulin Secretion from Pancreatic Beta-Cells by Activating AMPK. Pharmaceutical Research [Internet]. 2017;34(12):2873–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030673632&doi=10.1007%252fs11095-017-2271-7&partnerID=40&md5=cb9b215a539f7b317713abe9bea3ee8a

13.

Shamni O, Cohen G, Gruzman A, Zaid H, Klip A, Cerasi E, et al. Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose. Data in Brief [Internet]. 2017;14:329–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026782636&doi=10.1016%252fj.dib.2017.07.069&partnerID=40&md5=47c72d1d2cc0c857f7c65f0d7fb0716f

14.

Shamni O, Cohen G, Gruzman A, Zaid H, Klip A, Cerasi E, et al. Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose. Biochimica et Biophysica Acta - Biomembranes [Internet]. 2017;1859(10):1900–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021655084&doi=10.1016%252fj.bbamem.2017.06.013&partnerID=40&md5=5863878ba860f61007e949e2f1df4c58

15.

Sasson S. Nutrient overload, lipid peroxidation and pancreatic beta cell function. Free Radical Biology and Medicine [Internet]. 2017;111:102–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011088506&doi=10.1016%252fj.freeradbiomed.2016.09.003&partnerID=40&md5=df619adfe93826a4dfb2fc116b05ad1a

16.

Sasson S. 4-Hydroxyalkenal-activated PPARδ mediates hormetic interactions in diabetes. Biochimie [Internet]. 2017;136:85–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006137745&doi=10.1016%252fj.biochi.2016.10.007&partnerID=40&md5=7c9acb8b8da9a157914eefaddf70579f

17.

Ridker PM, Revkin J, Amarenco P, Brunell R, Curto M, Civeira F, et al. Cardiovascular efficacy and safety of bococizumab in high-risk patients. New England Journal of Medicine [Internet]. 2017;376(16):1527–39. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018314556&doi=10.1056%252fNEJMoa1701488&partnerID=40&md5=f2d49739539922b8a7b9b7461e8be08d

18.

Maulucci G, Cohen O, Daniel B, Sansone A, Petropoulou PI, Filou S, et al. Fatty acid-related modulations of membrane fluidity in cells: detection and implications. Free Radical Research [Internet]. 2016;50:S40–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992401765&doi=10.1080%252f10715762.2016.1231403&partnerID=40&md5=d6f96587287f752e5e02fb0c6335888c

19.

Maulucci G, Daniel B, Cohen O, Avrahami Y, Sasson S. Hormetic and regulatory effects of lipid peroxidation mediators in pancreatic beta cells. Molecular Aspects of Medicine [Internet]. 2016;49:49–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962045930&doi=10.1016%252fj.mam.2016.03.001&partnerID=40&md5=de3d088c1d2f90d66cb16c538f9c1ebf

20.

Karavia EA, Hatziri A, Kalogeropoulou C, Papachristou NI, Xepapadaki E, Constantinou C, et al. Deficiency in apolipoprotein A-I ablates the pharmacological effects of metformin on plasma glucose homeostasis and hepatic lipid deposition. European Journal of Pharmacology [Internet]. 2015;766:76–85. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944730284&doi=10.1016%252fj.ejphar.2015.09.040&partnerID=40&md5=a9956f1d28d97709c39fdd462bf5938d

21.

Stancu CS, Carnuta MG, Sanda GM, Toma L, Deleanu M, Niculescu LS, et al. Hyperlipidemia-induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian hamsters. Molecular Nutrition and Food Research [Internet]. 2015;59(11):2293–302. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941711251&doi=10.1002%252fmnfr.201500422&partnerID=40&md5=bb211e42fef2ff25a3f22d262e62f01e

22.

Riahi Y, Kaiser N, Cohen G, Abd-Elrahman I, Blum G, Shapira OM, et al. Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner. Journal of Cellular and Molecular Medicine [Internet]. 2015;19(8):1887–99. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938216645&doi=10.1111%252fjcmm.12561&partnerID=40&md5=bbd9d63834e1fac121dc34571859e6cd

23.

Manea SA, Constantin A, Manda G, Sasson S, Manea A. Regulation of Nox enzymes expression in vascular pathophysiology: Focusing on transcription factors and epigenetic mechanisms. Redox Biology [Internet]. 2015;5:358–66. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84933514292&doi=10.1016%252fj.redox.2015.06.012&partnerID=40&md5=d7427355943bd116e256a9f169db7517

24.

Cohen G, Shamni O, Avrahami Y, Cohen O, Broner EC, Filippov-Levy N, et al. Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation. Diabetologia [Internet]. 2015;58(6):1333–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939938054&doi=10.1007%252fs00125-015-3566-z&partnerID=40&md5=8c7b98063dec288aeecb00a7345e99c5

25.

Kahremany S, Livne A, Gruzman A, Senderowitz H, Sasson S. Activation of PPARδ: From computer modelling to biological effects. British Journal of Pharmacology [Internet]. 2015;172(3):754–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920774079&doi=10.1111%252fbph.12950&partnerID=40&md5=ccf6384efa04712e8df0c8f0c120b0ae

26.

Pasternak L, Meltzer-Mats E, Babai-Shani G, Cohen G, Viskind O, Eckel J, et al. Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via ampk activation. Chemical Communications [Internet]. 2014;50(76):11222–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84906675670&doi=10.1039%252fc4cc03310h&partnerID=40&md5=abc1476252564ea61b7779bc33df9881

27.

Cohen G, Riahi Y, Sunda V, Deplano S, Chatgilialoglu C, Ferreri C, et al. Signaling properties of 4-hydroxyalkenals formed by lipid peroxidation in diabetes. Free Radical Biology and Medicine [Internet]. 2013;65:978–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884373560&doi=10.1016%252fj.freeradbiomed.2013.08.163&partnerID=40&md5=701e90eea5bd279087ffb3a2c09c6c4a

28.

Jaganjac M, Tirosh O, Cohen G, Sasson S, Zarkovic N. Reactive aldehydes-second messengers of free radicals in diabetes mellitus. Free Radical Research [Internet]. 2013;47(S1):39–48. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881230708&doi=10.3109%252f10715762.2013.789136&partnerID=40&md5=30cb290d8ab4b033d9e8fbac44889997

29.

Meltzer-Mats E, Babai-Shani G, Pasternak L, Uritsky N, Getter T, Viskind O, et al. Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives. Journal of Medicinal Chemistry [Internet]. 2013;56(13):5335–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880147061&doi=10.1021%252fjm4001488&partnerID=40&md5=8c6e9ac801a34d2492a9a9f910f8c75d

30.

Kapitulnik J, Benaim C, Sasson S. Endothelial cells derived from the blood-brain barrier and islets of Langerhans differ in their response to the effects of bilirubin on oxidative stress under hyperglycemic conditions. Frontiers in Pharmacology [Internet]. 2012;3 JUL. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84866176709&doi=10.3389%252ffphar.2012.00131&partnerID=40&md5=1df1d8117f5bbec19f2fb0d3046dca93

31.

Gruzman A, Elgart A, Viskind O, Billauer H, Dotan S, Cohen G, et al. Antihyperglycaemic activity of 2,4:3,5-dibenzylidene-D-xylose-diethyl dithioacetal in diabetic mice. Journal of Cellular and Molecular Medicine [Internet]. 2012;16(3):593–603. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857019474&doi=10.1111%252fj.1582-4934.2011.01340.x&partnerID=40&md5=087b245ac640d416a748073f761413be

32.

Cohen G, Riahi Y, Shamni O, Guichardant M, Chatgilialoglu C, Ferreri C, et al. Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion. Diabetes [Internet]. 2011;60(11):2830–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80755152865&doi=10.2337%252fdb11-0347&partnerID=40&md5=b6b8f59aad022d2ba95829794dd0d768

33.

Lamers D, Schlich R, Greulich S, Sasson S, Sell H, Eckel J. Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells. Journal of Cellular and Molecular Medicine [Internet]. 2011;15(5):1177–88. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79957581507&doi=10.1111%252fj.1582-4934.2010.01099.x&partnerID=40&md5=709c2472930e6ae32a1d4408ed23bacc

34.

Riahi Y, Cohen G, Shamni O, Sasson S. Signaling and cytotoxic functions of 4-hydroxyalkenals. American Journal of Physiology - Endocrinology and Metabolism [Internet]. 2010;299(6):E879–86. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649676178&doi=10.1152%252fajpendo.00508.2010&partnerID=40&md5=b9c7442b65adb8e76a93ecb38e54922a

35.

Negre-Salvayre A, Auge N, Ayala V, Basaga H, Boada J, Brenke R, et al. Pathological aspects of lipid peroxidation. Free Radical Research [Internet]. 2010;44(10):1125–71. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956574773&doi=10.3109%252f10715762.2010.498478&partnerID=40&md5=05d23832dd0263bbcc4c88e3c3915bbf

36.

Riahi Y, Sin-Malia Y, Cohen G, Alpert E, Gruzman A, Eckel J, et al. The natural protective mechanism against hyperglycemia in vascular endothelial cells: Roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor δ. Diabetes [Internet]. 2010;59(4):808–18. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77951197658&doi=10.2337%252fdb09-1207&partnerID=40&md5=60fb3c1c7e9766c63b9a9c3b7f3c9c3a

37.

Gruzman A, Shamni O, Yakir MB, Sandovski D, Elgart A, Alpert E, et al. Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase α. Journal of Medicinal Chemistry [Internet]. 2008;51(24):8096–108. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-58149095366&doi=10.1021%252fjm8008713&partnerID=40&md5=cd3e15ff4604cc207138fa008206cb92

38.

Yakir MB, Katzhendler Y, Sasson S. The search for potent alpha-lipoic acid derivatives: Chemical and pharmacological aspects [Internet]. Lipoic Acid: Energy Production, Antioxidant Activity and Health Effects. 2008. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84912055078&partnerID=40&md5=59ba933edf7f65fa09212cecb8ffce5f

39.

Alpert E, Gruzman A, Tennenbaum T, Sasson S. Selective cyclooxygenase-2 inhibitors stimulate glucose transport in L6 myotubes in a protein kinase Cδ-dependent manner. Biochemical Pharmacology [Internet]. 2007;73(3):368–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845635702&doi=10.1016%252fj.bcp.2006.10.008&partnerID=40&md5=c17a32bd832fe091a6f419d8946af3c8

40.

Vahsen S, Rakowski K, Ledwig D, Dietze-Schroeder D, Swifka J, Sasson S, et al. Altered GLUT4 translocation in skeletal muscle of 12/15-lipoxygenase knockout mice. Hormone and Metabolic Research [Internet]. 2006;38(6):391–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745917065&doi=10.1055%252fs-2006-944531&partnerID=40&md5=ab6e65ede21408cc0222dcf943503256

41.

Alpert E, Gruzman A, Lardi-Studler B, Cohen G, Reich R, Sasson S. Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin-and AMPKα-independent manner. Diabetologia [Internet]. 2006;49(3):562–70. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33244485463&doi=10.1007%252fs00125-005-0122-2&partnerID=40&md5=135ed8a2bf29dd03f13e3ddae9f7a633

42.

Totary-Jain H, Naveh-Many T, Riahi Y, Kaiser N, Eckel J, Sasson S. Calreticulin destabilizes glucose transporter-1 mRNA in vascular endothelial and smooth muscle cells under high-glucose conditions. Circulation Research [Internet]. 2005;97(10):1001–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-27944477788&doi=10.1161%252f01.RES.0000189260.46084.e5&partnerID=40&md5=ab6c75fb577eeb76d8ecd2fd8cb134c0

43.

Alpert E, Gruzman A, Riahi Y, Blejter R, Aharoni P, Weisinger G, et al. Delayed autoregulation of glucose transport in vascular endothelial cells. Diabetologia [Internet]. 2005;48(4):752–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-17844369493&doi=10.1007%252fs00125-005-1681-y&partnerID=40&md5=de63799a913f11e9dc5965b1d7d96a1b

44.

Alpert E, Altman H, Totary H, Gruzman A, Barnea D, Barash V, et al. 4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells. Biochemical Pharmacology [Internet]. 2004;67(10):1985–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-2342575652&doi=10.1016%252fj.bcp.2004.02.005&partnerID=40&md5=94ad0a622ee1a2c1dad1403cac4725fa

45.

Gruzman A, Hidmi A, Katzhendler J, Haj-Yehie A, Sasson S. Synthesis and characterization of new and potent α-lipoic acid derivatives. Bioorganic and Medicinal Chemistry [Internet]. 2004;12(5):1183–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-1342343121&doi=10.1016%252fj.bmc.2003.11.025&partnerID=40&md5=70470b959d13227dfd81b80c031d85fe

46.

Krimsky M, Yedgar S, Aptekar L, Schwob O, Goshen G, Gruzman A, et al. Amelioration of TNBS-induced colon inflammation in rats by phospholipase A2 inhibitor. American Journal of Physiology - Gastrointestinal and Liver Physiology [Internet]. 2003;285(3 48-3):G586–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0041464463&doi=10.1152%252fajpgi.00463.2002&partnerID=40&md5=3dbd1e1a01f749449de0840ab1cfd456

47.

Noyman I, Marikovsky M, Sasson S, Stark AH, Bernath K, Seger R, et al. Hyperglycemia reduces nitric oxide synthase and glycogen synthase activity in endothelial cells. Nitric Oxide - Biology and Chemistry [Internet]. 2002;7(3):187–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-1842867750&doi=10.1016%2fS1089-8603%2802%2900106-4&partnerID=40&md5=b94c3effa886054cbeb44d78ccd4d7ce

48.

Alpert E, Gruzman A, Totary H, Kaiser N, Reich R, Sasson S. A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: Role of glucose and 12-hydroxyeicosatetraenoic acid. Biochemical Journal [Internet]. 2002;362(2):413–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036499692&doi=10.1042%252f0264-6021%253a3620413&partnerID=40&md5=a8ff11217fc7cc91c5beb40f889985af

49.

Dransfeld O, Rakatzi I, Sasson S, Eckel J. Eicosanoids and the regulation of cardiac glucose transport. Annals of the New York Academy of Sciences [Internet]. 2002;967:208–16. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036297757&doi=10.1111%252fj.1749-6632.2002.tb04277.x&partnerID=40&md5=e017ab3065a5d488e60ac6c1b2613a88

50.

Dransfeld O, Rakatzi I, Sasson S, Gruzman A, Schmitt M, Häussinger D, et al. Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements. Biochemical Journal [Internet]. 2001;359(1):47–54. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035476416&doi=10.1042%252f0264-6021%253a3590047&partnerID=40&md5=fc803db5438dfa3b0374121f17e717d7

51.

Von Der Crone S, Deppe C, Barthel A, Sasson S, Joost HG, Schürmann A. Glucose deprivation induces Akt-dependent synthesis and incorporation of GLUT1, but not of GLUT4, into the plasma membrane of 3T3-L1 adipocytes. European Journal of Cell Biology [Internet]. 2000;79(12):943–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034532663&doi=10.1078%252f0171-9335-00118&partnerID=40&md5=ea7719896df24cdc4bc37f4cb6a6eb21

52.

Dransfeld O, Uphues I, Sasson S, Schürmann A, Joost HG, Eckel J. Regulation of subcellular distribution of GLUT4 in cardiomyocytes: Rab4A reduces basal glucose transport and augments insulin responsiveness. Experimental and Clinical Endocrinology and Diabetes [Internet]. 2000;108(1):26–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034102592&doi=10.1055%252fs-0032-1329212&partnerID=40&md5=d679b0c7c2e872efdd2f618524fd0da9

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Yudt MR, Vorojeikina D, Zhong L, Skafar DF, Sasson S, Gasiewicz TA, et al. Function of estrogen receptor tyrosine 537 in hormone binding, DNA binding, and transactivation. Biochemistry [Internet]. 1999;38(43):14146–56. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033607306&doi=10.1021%252fbi9911132&partnerID=40&md5=79431a9596118745e93d9053277bc1f6

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Dimitriadis G, Leighton B, Parry-Billings M, Sasson S, Young M, Krause U, et al. Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle. Biochemical Journal [Internet]. 1997;321(3):707–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031059756&doi=10.1042%252fbj3210707&partnerID=40&md5=dedea08ca2c122498c13f8ba618ee88e

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Sasson S, Kaiser N, Dan-Goor M, Oron R, Koren S, Wertheimer E, et al. Substrate autoregulation of glucose transport: Hexose 6-phosphate mediates the cellular distribution of glucose transporters. Diabetologia [Internet]. 1997;40(1):30–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031012995&doi=10.1007%252fs001250050639&partnerID=40&md5=aaeadd866157ebe8cfcf44311e9a7af7

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Arnold SF, Melamed M, Vorojeikina DP, Notides AC, Sasson S. Estradiol-binding mechanism and binding capacity of the human estrogen receptor is regulated by tyrosine phosphorylation. Molecular Endocrinology [Internet]. 1997;11(1):48–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031036099&doi=10.1210%252fmend.11.1.9876&partnerID=40&md5=338c32c8564614ab2ef4d8dc0a0a894f

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Melamed M, Castaño E, Notides AC, Sasson S. Molecular and kinetic basis for the mixed agonist/antagonist activity of estriol. Molecular Endocrinology [Internet]. 1997;11(12):1868–78. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030685806&doi=10.1210%252fmend.11.12.0025&partnerID=40&md5=ea71920df03f92606ee92a33daddd530

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Melamed M, Arnold SF, Notides AC, Sasson S. Kinetic analysis of the interaction of human estrogen receptor with an estrogen response element. Journal of Steroid Biochemistry and Molecular Biology [Internet]. 1996;57(3–4):153–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029890415&doi=10.1016%2f0960-0760%2895%2900264-2&partnerID=40&md5=ecbbb9b161abb0fa1a03c3a78fc92ac7

59.

Sasson S, Gorowits N, Joost HG, King GL, Cerasi E, Kaiser N. Regulation by metformin of the hexose transport system in vascular endothelial and smooth muscle cells. British Journal of Pharmacology [Internet]. 1996;117(6):1318–24. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029867131&doi=10.1111%252fj.1476-5381.1996.tb16731.x&partnerID=40&md5=1d9805765b81147722cce223dcfaac1e

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Youngren JF, Maddux BA, Sasson S, Sbraccia P, Tapscott EB, Swanson MS, et al. Skeletal muscle content of membrane glycoprotein PC-1 in obesity: Relationship to muscle glucose transport. Diabetes [Internet]. 1996;45(10):1324–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029742448&doi=10.2337%252fdiab.45.10.1324&partnerID=40&md5=47a3bb5884c0950be273b76799dc2304

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Maddux BA, Sbraccia P, Kumakura S, Sasson S, Youngren J, Fisher A, et al. Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature [Internet]. 1995;373(6513):448–51. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028795761&doi=10.1038%252f373448a0&partnerID=40&md5=a923d9950a135a640ed31f89399923fb

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Sasson S, Ashhab Y, Melloul D, Cerasi E. Autoregulation of glucose transport: Effects of glucose on glucose transporter expression and cellular location in muscle. Advances in Experimental Medicine and Biology [Internet]. 1993;334:113–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027483683&doi=10.1007%252f978-1-4615-2910-1_9&partnerID=40&md5=04f58d5c51698e3f400dadbd6986a49e

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Sasson S, Oron R, Cerasi E. Enzymatic assay of 2-deoxyglucose 6-phosphate for assessing hexose uptake rates in cultured cells. Analytical Biochemistry [Internet]. 1993;215(2):309–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027438887&doi=10.1006%252fabio.1993.1594&partnerID=40&md5=86e13a53370b44d05d16c01ad8e149e3

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Kaiser N, Sasson S, Feener EP, Boukobza-Vardi N, Higashi S, Moller DE, et al. Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells. Diabetes [Internet]. 1993;42(1):80–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027395183&doi=10.2337%252fdiab.42.1.80&partnerID=40&md5=c820d38cec691d473bb31d98d8bd0e5d

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Bond JP, Sasson S, Notides AC. The binding of estrogen and estrogen antagonists to the estrogen receptor. Archives of Biochemistry and Biophysics [Internet]. 1992;296(2):583–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026667650&doi=10.1016%2f0003-9861%2892%2990614-3&partnerID=40&md5=ae1c8c965498efe3d90b2ac5796415b3

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Greco-Perotto R, Wertheimer E, Jeanrenaud B, Cerasi E, Sasson S. Glucose regulates its transport in L8 myocytes by modulating cellular trafficking of the transporter GLUT-1. Biochemical Journal [Internet]. 1992;286(1):157–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026649530&doi=10.1042%252fbj2860157&partnerID=40&md5=ecb8d178c3878e5cc6b023907835efd8

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Wertheimer E, Sasson S, Cerasi E, Ben-Neriah Y. The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1991;88(6):2525–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026019757&doi=10.1073%252fpnas.88.6.2525&partnerID=40&md5=f7a7e261a2bace792ce4c77276207461

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Sasson S. Equilibrium binding analysis of estrogen agonists and antagonists: relation to the activation of the estrogen receptor. Pathologie Biologie [Internet]. 1991;39(1):59–69. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025963493&partnerID=40&md5=cb6bdfe0edfb99170d9b6925d7b8f9f8

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Sasson S, Kunievsky B, Nathan C, Ceras E. On the role of 5-hydroxytryptamine in the peripheral action of fenfluramine: studies with the isolated rat soleus muscle. Biochemical Pharmacology [Internet]. 1990;39(5):965–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025060160&doi=10.1016%2f0006-2952%2890%2990215-7&partnerID=40&md5=8279797c7a74e1489a0d06b11c6b9865

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Wertheimer E, Sasson S, Cerasi E. Regulation of hexose transport in L8 myocytes by glucose: Possible sites of interaction. Journal of Cellular Physiology [Internet]. 1990;143(2):330–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025364056&doi=10.1002%252fjcp.1041430217&partnerID=40&md5=300b222df60539c8058c7a1c1f7b1f94

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Sasson S, Kunievsky B, Nathan C, Cerasi E. Failure of fenfluramine to affect basal and insulin-stimulated hexose transport in rat skeletal muscle. Biochemical Pharmacology [Internet]. 1989;38(16):2655–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024322161&doi=10.1016%2f0006-2952%2889%2990551-0&partnerID=40&md5=4cde61e579ba81ce039cbb41a08197cf

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Sasson S, Katzenellenbooen JA. Reversible, positive cooperative interaction of 11β-chloromethyl-[3H]estradiol-17β with the calf uterine estrogen receptor. Journal of Steroid Biochemistry [Internet]. 1989;33(5):859–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024792392&doi=10.1016%2f0022-4731%2889%2990233-1&partnerID=40&md5=cdc62a71119657c32806bb0795096836

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Sasson S, Notides AC. The effects of dimethylformamide on the interaction of the estrogen receptor with estradiol. Journal of Steroid Biochemistry [Internet]. 1988;29(5):491–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023934015&doi=10.1016%2f0022-4731%2888%2990183-5&partnerID=40&md5=9888a80775f9bb3a7801474d740b3741

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Sasson S, Notides AC. Mechanism of the estrogen receptor interaction with 4-hydroxytamoxifen. Molecular Endocrinology [Internet]. 1988;2(4):307–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023878971&doi=10.1210%252fmend-2-4-307&partnerID=40&md5=63da9c34f213c193530552a176bec4fd

75.

Amir S, Sasson S, Kaiser N, Meyerovitch J, Shechter Y. Polymyxin B is an inhibitor of insulin-induced hypoglycemia in the whole animal model. Studies on the mode of inhibitory action. Journal of Biological Chemistry [Internet]. 1987;262(14):6663–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023278991&partnerID=40&md5=7291f434dcdd615b65b1f010d35ec088

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Sasson S, Edelson D, Cerasi E. In vitro autoregulation of glucose utilization in rat soleus muscle. Diabetes [Internet]. 1987;36(9):1041–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023200469&doi=10.2337%252fdiab.36.9.1041&partnerID=40&md5=10865ee530300f92f34495caef4491fc

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Sasson S, Cerasi E. Substrate regulation of the glucose transport system in rat skeletal muscle. Characterization and kinetic analysis in isolated soleus muscle and skeletal muscle cells in culture. Journal of Biological Chemistry [Internet]. 1986;261(36):16827–33. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023034661&partnerID=40&md5=57b6fd2c8512df10fde9f13d5adbc19b

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Sasson S, Notides AC. Inability of [3H]estriol to induce maximal cooperativity of the estrogen receptor. Journal of Steroid Biochemistry [Internet]. 1984;20(4 PART 2):1027–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021287681&doi=10.1016%2f0022-4731%2884%2990014-1&partnerID=40&md5=cec20b551135f3f9a573a14559941bb2

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Sasson S, Notides AC. The estriol-induced inhibition of the estrogen receptor’s positive cooperativity. Journal of Steroid Biochemistry [Internet]. 1984;20(4 PART 2):1021–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021262759&doi=10.1016%2f0022-4731%2884%2990013-X&partnerID=40&md5=4649a26b4301c6f7b8c8c75c0041bbe1

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Sasson S, Notides AC. Estriol and estrone interaction with the estrogen receptor. II. Estriol and estrone-induced inhibition of the cooperative binding of [3H]estradiol to the estrogen receptor. Journal of Biological Chemistry [Internet]. 1983;258(13):8118–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020957920&partnerID=40&md5=3826c099d5143cfecf4fbca543a9e70a

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Sasson S, Notides AC. The inhibition of the estrogen receptor’s positive cooperative [3H]estradiol binding by the antagonist, clomiphene. Journal of Biological Chemistry [Internet]. 1982;257(19):11540–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020395816&partnerID=40&md5=1e2392a58750465b348c0ea87ef3d545

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Sasson S, Mayer M. Interactions of androgenic steroids with thymus cells in vivo and in vitro. Israel Journal of Medical Sciences [Internet]. 1982;17(12):1198–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019965552&partnerID=40&md5=784675129533d41e0329decc9354d197

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Sasson S, Mayer M. Resistance to androgen in murine lymphosarcoma lines resistant or sensitive to glucocorticoid hormone. British Journal of Cancer [Internet]. 1981;44(1):127–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019464054&doi=10.1038%252fbjc.1981.158&partnerID=40&md5=85d586fed46686d71438f931e18ed666

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Sasson S, Mayer M. Effect of androgenic steroids on rat thymus and thymocytes in suspension. Journal of Steroid Biochemistry [Internet]. 1981;14(6):509–17. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019446235&doi=10.1016%2f0022-4731%2881%2990023-6&partnerID=40&md5=1234333f5e955c44d81931fc72ed43b4