School of Pharmacy : Gibson Dan

1.

Babu T, Ghareeb H, Basu U, Schueffl H, Theiner S, Heffeter P, et al. Oral Anticancer Heterobimetallic PtIV−AuI Complexes Show High In Vivo Activity and Low Toxicity. Angewandte Chemie - International Edition [Internet]. 2023;62(10). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147098113&doi=10.1002%252fanie.202217233&partnerID=40&md5=43feb63c69b46014d2f1a662c050a409

2.

Mendrina T, Poetsch I, Schueffl H, Baier D, Pirker C, Ries A, et al. Influence of the Fatty Acid Metabolism on the Mode of Action of a Cisplatin(IV) Complex with Phenylbutyrate as Axial Ligands. Pharmaceutics [Internet]. 2023;15(2). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149120482&doi=10.3390%252fpharmaceutics15020677&partnerID=40&md5=57bf307d75d906460b0ed5063921192b

3.

Sarkar A, Novohradsky V, Maji M, Babu T, Markova L, Kostrhunova H, et al. Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death. Angewandte Chemie - International Edition [Internet]. 2023; Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85170356579&doi=10.1002%252fanie.202310774&partnerID=40&md5=7fdc2c259606c02ad9655031705e2857

4.

Liu X, Barth MC, Cseh K, Kowol CR, Jakupec MA, Keppler BK, et al. Oxoplatin-Based Pt(IV) Lipoate Complexes and Their Biological Activity. Chemistry and Biodiversity [Internet]. 2022;19(10). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138300768&doi=10.1002%252fcbdv.202200695&partnerID=40&md5=02bda26f24291e51fd75927a21d5083d

5.

Liu X, Wenisch D, Barth MC, Cseh K, Kowol CR, Jakupec MA, et al. Novel oxaliplatin(iv) complexes conjugated with ligands bearing pendant 1,2-dithiolane/1,2-diselenolane/cyclopentyl motifs. Dalton Transactions [Internet]. 2022;51(44):16824–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140452614&doi=10.1039%252fd2dt02217f&partnerID=40&md5=2208c8cee0fc9fa0140dc85a6f5e384f

6.

Lachowicz JI, Mateddu A, Coni P, Caltagirone C, Murgia S, Gibson D, et al. Study of the DNA binding mechanism and in vitro activity against cancer cells of iron(iii) and aluminium(iii) kojic acid derivative complexes. Dalton Transactions [Internet]. 2022; Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128800025&doi=10.1039%252fd2dt00111j&partnerID=40&md5=f7553f2c43a07397541baed7a61566da

7.

Schmidt C, Babu T, Kostrhunova H, Timm A, Basu U, Ott I, et al. Are Pt(IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs? Journal of Medicinal Chemistry [Internet]. 2021;64(15):11364–78. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113672481&doi=10.1021%252facs.jmedchem.1c00706&partnerID=40&md5=a7315309d4c2c16a77e9575e027765d4

8.

Gibson D. Pt(IV) Anticancer Prodrugs – A Tale of Mice and Men. ChemMedChem [Internet]. 2021;16(14):2188–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105611906&doi=10.1002%252fcmdc.202100115&partnerID=40&md5=e89be8bfd0ef6cc38dd8113e4e7136a8

9.

Gibson D. Platinum(IV) anticancer agents; are we en route to the holy grail or to a dead end? Journal of Inorganic Biochemistry [Internet]. 2021;217. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100032319&doi=10.1016%252fj.jinorgbio.2020.111353&partnerID=40&md5=9bc67a5787c877d165e07b46acb45eea

10.

Karmakar S, Kostrhunova H, Ctvrtlikova T, Novohradsky V, Gibson D, Brabec V. Platinum(IV)-Estramustine Multiaction Prodrugs Are Effective Antiproliferative Agents against Prostate Cancer Cells. Journal of Medicinal Chemistry [Internet]. 2020;63(22):13861–77. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096562338&doi=10.1021%252facs.jmedchem.0c01400&partnerID=40&md5=2222665b1b8162596aa6f478aa31f8a1

11.

Khattib D, Ishan M, Karmakar S, Kostrhunova H, Brabec V, Gibson D. Oxidation of cis-Diamminediacetato PtII with Hydrogen Peroxide Can Give Rise to Two Isomeric PtIV Products. Chemistry - A European Journal [Internet]. 2020;26(43):9475–80. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087647512&doi=10.1002%252fchem.202001472&partnerID=40&md5=d3963b29e94275ebe1a998812f9d21e1

12.

Chen CKJ, Kappen P, Gibson D, Hambley TW. trans-Platinum(iv) pro-drugs that exhibit unusual resistance to reduction by endogenous reductants and blood serum but are rapidly activated inside cells:1H NMR and XANES spectroscopy study. Dalton Transactions [Internet]. 2020;49(23):7722–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086509747&doi=10.1039%252fd0dt01622e&partnerID=40&md5=e144fc853a240197660b1f69360a37eb

13.

Karges J, Yempala T, Tharaud M, Gibson D, Gasser G. A Multi-action and Multi-target RuII–PtIV Conjugate Combining Cancer-Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers. Angewandte Chemie - International Edition [Internet]. 2020;59(18):7069–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081330898&doi=10.1002%252fanie.201916400&partnerID=40&md5=6ef37aea5c6f83f4e432050462c46fd9

14.

Babu T, Sarkar A, Karmakar S, Schmidt C, Gibson D. Multiaction Pt(IV) Carbamate Complexes Can Codeliver Pt(II) Drugs and Amine Containing Bioactive Molecules. Inorganic Chemistry [Internet]. 2020;59(7):5182–93. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85082663652&doi=10.1021%252facs.inorgchem.0c00445&partnerID=40&md5=6edc06fe657b411e5f68ba74d294143f

15.

Yempala T, Babu T, Gibson D, Cassels BK. Dibenzofuran annulated 1-azepines: Synthesis and cytotoxicity. Synthetic Communications [Internet]. 2020;50(3):438–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077395274&doi=10.1080%252f00397911.2019.1703001&partnerID=40&md5=36d76405872da076342a48e0e5216af4

16.

Karmakar S, Poetsch I, Kowol CR, Heffeter P, Gibson D. Synthesis and Cytotoxicity of Water-Soluble Dual- A nd Triple-Action Satraplatin Derivatives: Replacement of Equatorial Chlorides of Satraplatin by Acetates. Inorganic Chemistry [Internet]. 2019;58(24):16676–88. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076291112&doi=10.1021%252facs.inorgchem.9b02796&partnerID=40&md5=c9f62ddf2d11ec4ebeff08b3425f8f20

17.

Yempala T, Babu T, Karmakar S, Nemirovski A, Ishan M, Gandin V, et al. Expanding the Arsenal of PtIV Anticancer Agents: Multi-action PtIV Anticancer Agents with Bioactive Ligands Possessing a Hydroxy Functional Group. Angewandte Chemie - International Edition [Internet]. 2019;58(50):18218–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074600212&doi=10.1002%252fanie.201910014&partnerID=40&md5=53aa3038de89018e7b252a6e578c5bb1

18.

Babak MV, Zhi Y, Czarny B, Toh TB, Hooi L, Chow EKH, et al. Dual-Targeting Dual-Action Platinum(IV) Platform for Enhanced Anticancer Activity and Reduced Nephrotoxicity. Angewandte Chemie - International Edition [Internet]. 2019;58(24):8109–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064594336&doi=10.1002%252fanie.201903112&partnerID=40&md5=d15ff7d28ee4f979491f2f5e61481eb4

19.

Kostrhunova H, Zajac J, Novohradsky V, Kasparkova J, Malina J, Aldrich-Wright JR, et al. A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton. Journal of Medicinal Chemistry [Internet]. 2019;62(10):5176–90. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066013834&doi=10.1021%252facs.jmedchem.9b00489&partnerID=40&md5=f77f458f3a9b4d5a2a3a1da1c8397edb

20.

Kostrhunova H, Petruzzella E, Gibson D, Kasparkova J, Brabec V. An Anticancer Pt IV Prodrug That Acts by Mechanisms Involving DNA Damage and Different Epigenetic Effects. Chemistry - A European Journal [Internet]. 2019;25(20):5235–45. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063990925&doi=10.1002%252fchem.201805626&partnerID=40&md5=041826055472b11032484f606e0face7

21.

Gibson D. Multi-action Pt(IV) anticancer agents; do we understand how they work? Journal of Inorganic Biochemistry [Internet]. 2019;191:77–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056876933&doi=10.1016%252fj.jinorgbio.2018.11.008&partnerID=40&md5=7f5457ca92c745b509b860050fc36a58

22.

Petruzzella E, Sirota R, Solazzo I, Gandin V, Gibson D. Triple action Pt(iv) derivatives of cisplatin: A new class of potent anticancer agents that overcome resistance. Chemical Science [Internet]. 2018;9(18):4299–307. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046843728&doi=10.1039%252fc8sc00428e&partnerID=40&md5=fad3d059d4cdde75189460ebf94a0404

23.

Novohradsky V, Zanellato I, Marzano C, Pracharova J, Kasparkova J, Gibson D, et al. Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates. Scientific Reports [Internet]. 2017;7(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020869193&doi=10.1038%252fs41598-017-03864-w&partnerID=40&md5=caa3411f62aa077d0e881569c5035179

24.

Petruzzella E, Braude JP, Aldrich-Wright JR, Gandin V, Gibson D. A Quadruple-Action Platinum(IV) Prodrug with Anticancer Activity Against KRAS Mutated Cancer Cell Lines. Angewandte Chemie - International Edition [Internet]. 2017;56(38):11539–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028890149&doi=10.1002%252fanie.201706739&partnerID=40&md5=388a7abbc7d84c5f8461c5e8a101581e

25.

Harper BWJ, Friedman-Ezra A, Sirota R, Petruzzella E, Aldrich-Wright JR, Gibson D. Probing the Interactions of Cytotoxic [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)] and Its PtIV Derivatives with Human Serum. ChemMedChem [Internet]. 2017;12(7):510–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017009482&doi=10.1002%252fcmdc.201700092&partnerID=40&md5=71f81a88485d6476c09e280191ec03e7

26.

Sirota R, Gibson D, Kohen R. The timing of caffeic acid treatment with cisplatin determines sensitization or resistance of ovarian carcinoma cell lines. Redox Biology [Internet]. 2017;11:170–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85003794167&doi=10.1016%252fj.redox.2016.12.006&partnerID=40&md5=9e8c24695cd48ed48ce1d19475a4af75

27.

Harper BWJ, Petruzzella E, Sirota R, Faccioli FF, Aldrich-Wright JR, Gandin V, et al. Synthesis, characterization and: In vitro and in vIVo anticancer actIVity of Pt(IV) derIVatIVes of [Pt(1 S,2 S -DACH)(5,6-dimethyl-1,10-phenanthroline)]. Dalton Transactions [Internet]. 2017;46(21):7005–19. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021754694&doi=10.1039%252fc7dt01054k&partnerID=40&md5=3fdb154ac150e8a141a095b5e505c4c0

28.

Abu Ammar A, Raveendran R, Gibson D, Nassar T, Benita S. A Lipophilic Pt(IV) Oxaliplatin Derivative Enhances Antitumor Activity. Journal of Medicinal Chemistry [Internet]. 2016;59(19):9035–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84991369096&doi=10.1021%252facs.jmedchem.6b00955&partnerID=40&md5=916654582e1c7faa33e6c7cf7b835622

29.

Raveendran R, Braude JP, Wexselblatt E, Novohradsky V, Stuchlikova O, Brabec V, et al. Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action. Chemical Science [Internet]. 2016;7(3):2381–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959377689&doi=10.1039%252fc5sc04205d&partnerID=40&md5=15ab31bc68a2935e70cbcdc70e93eb37

30.

Zajac J, Kostrhunova H, Novohradsky V, Vrana O, Raveendran R, Gibson D, et al. Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin. Journal of Inorganic Biochemistry [Internet]. 2016;156:89–97. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954415054&doi=10.1016%252fj.jinorgbio.2015.12.003&partnerID=40&md5=dfe1930db2d178663dd7499e622e1e63

31.

Gibson D. Platinum(IV) anticancer prodrugs-hypotheses and facts. Dalton Transactions [Internet]. 2016;45(33):12983–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983315614&doi=10.1039%252fc6dt01414c&partnerID=40&md5=63df6da8307e2084ecebc095e699b03f

32.

Novohradsky V, Zerzankova L, Stepankova J, Vrana O, Raveendran R, Gibson D, et al. New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells. Biochemical Pharmacology [Internet]. 2015;95(3):133–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84936756705&doi=10.1016%252fj.bcp.2015.04.003&partnerID=40&md5=2546888a2a577f2ce811b5c420133f5f

33.

Sirota R, Gibson D, Kohen R. The role of the catecholic and the electrophilic moieties of caffeic acid in Nrf2/Keap1 pathway activation in ovarian carcinoma cell lines. Redox Biology [Internet]. 2015;4:48–59. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84917710616&doi=10.1016%252fj.redox.2014.11.012&partnerID=40&md5=5c012c6f9baec94bf786271bd8bc7de4

34.

Brabec V, Pracharova J, Novakova O, Gibson D, Kasparkova J. The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions. Dalton Transactions [Internet]. 2015;44(8):3573–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922800848&doi=10.1039%252fc4dt02603a&partnerID=40&md5=6d615c86c5bfc1a1728d29f75565c4e3

35.

Wexselblatt E, Raveendran R, Salameh S, Friedman-Ezra A, Yavin E, Gibson D. On the stability of PtIV pro-drugs with haloacetato ligands in the axial positions. Chemistry - A European Journal [Internet]. 2015;21(7):3108–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84921880258&doi=10.1002%252fchem.201405467&partnerID=40&md5=e9c98037a5689b3ab7ea8c55f330e437

36.

Li J, Pant A, Chin CF, Ang WH, Ménard-Moyon C, Nayak TR, et al. In vivo biodistribution of platinum-based drugs encapsulated into multi-walled carbon nanotubes. Nanomedicine: Nanotechnology, Biology, and Medicine [Internet]. 2014;10(7):1465–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84912150496&doi=10.1016%252fj.nano.2014.01.004&partnerID=40&md5=f437f109613c922adb54d98b10959e2a

37.

Novohradsky V, Zerzankova L, Stepankova J, Vrana O, Raveendran R, Gibson D, et al. Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands. Journal of Inorganic Biochemistry [Internet]. 2014;140:72–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904988798&doi=10.1016%252fj.jinorgbio.2014.07.004&partnerID=40&md5=b47ec56feb0987755a8f7d12433b7667

38.

Zivi E, Barash D, Aizenman E, Gibson D, Shufaro Y. Zygote serine decreased uptake from the fertilization medium is associated with implantation and pregnancy. Journal of Assisted Reproduction and Genetics [Internet]. 2014;31(7):889–97. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904381490&doi=10.1007%252fs10815-014-0231-2&partnerID=40&md5=34fca9e9bf0b5bf5b22d30e990cc8ce9

39.

Wexselblatt E, Yavin E, Gibson D. Platinum(IV) prodrugs with haloacetato ligands in the axial positions can undergo hydrolysis under biologically relevant conditions. Angewandte Chemie - International Edition [Internet]. 2013;52(23):6059–62. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84878392879&doi=10.1002%252fanie.201300640&partnerID=40&md5=7985d864a9415f8a922fa57549ef7fc7

40.

Prachařová J, Nováková O, Kašpárková J, Gibson D, Brabec V. Toxicity in tumor cells, DNA binding mode, and resistance to decomposition by sulfur nucleophiles of new dinuclear bifunctional trans-PtII complexes containing long alkane linkers. Pure and Applied Chemistry [Internet]. 2013;85(2):343–54. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873200270&doi=10.1351%252fPAC-CON-12-07-08&partnerID=40&md5=647345b134b8d569cff79ae8d3232f6d

41.

Zhang JZ, Bonnitcha P, Wexselblatt E, Klein AV, Najajreh Y, Gibson D, et al. Facile preparation of mono-, Di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design. Chemistry - A European Journal [Internet]. 2013;19(5):1672–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872729647&doi=10.1002%252fchem.201203159&partnerID=40&md5=3b16911aa9db077912e5f3595d9b0eb8

42.

Frybortova M, Novakova O, Stepankova J, Novohradsky V, Gibson D, Kasparkova J, et al. Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand. Journal of Inorganic Biochemistry [Internet]. 2013;126:46–54. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885346915&doi=10.1016%252fj.jinorgbio.2013.05.009&partnerID=40&md5=bfbe19c516d099db38af1610590dd40c

43.

Zhang JZ, Wexselblatt E, Hambley TW, Gibson D. Pt(iv) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate. Chemical Communications [Internet]. 2012;48(6):847–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84055197756&doi=10.1039%252fc1cc16647f&partnerID=40&md5=ae6d81728ec9e60993eec09a22c277ea

44.

Wexselblatt E, Gibson D. What do we know about the reduction of Pt(IV) pro-drugs? Journal of Inorganic Biochemistry [Internet]. 2012;117:220–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84869086138&doi=10.1016%252fj.jinorgbio.2012.06.013&partnerID=40&md5=a12956021ad6324caefebbd64151961d

45.

Wexselblatt E, Yavin E, Gibson D. Cellular interactions of platinum drugs. Inorganica Chimica Acta [Internet]. 2012;393:75–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84868580018&doi=10.1016%252fj.ica.2012.07.013&partnerID=40&md5=1d7c6be8a9b18dadc88d58b96151d00f

46.

Kostrhunova H, Kasparkova J, Gibson D, Brabec V. Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione. Molecular Pharmaceutics [Internet]. 2010;7(6):2093–102. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649968332&doi=10.1021%252fmp100080e&partnerID=40&md5=e027a0c19d5347f0bfd5c846cb2f2b23

47.

Kostrhunova H, Vrana O, Suchankova T, Gibson D, Kasparkova J, Brabec V. Different features of the DNA binding mode of antitumor cis -amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro. Chemical Research in Toxicology [Internet]. 2010;23(11):1833–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649257602&doi=10.1021%252ftx1002904&partnerID=40&md5=d575dec609b152ba45b3d37c8fa7244e

48.

Nemirovski A, Vinograd I, Takrouri K, Mijovilovich A, Rompel A, Gibson D. New reduction pathways for ctc-[PtCl2(CH3CO 2)2(NH3)(Am)] anticancer prodrugs. Chemical Communications [Internet]. 2010;46(11):1842–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949397213&doi=10.1039%252fb925721g&partnerID=40&md5=a00b2ce49cbdc342eef842d3377912c1

49.

Gibson D. The mechanism of action of platinum anticancer agents - What do we really know about it? Dalton Transactions [Internet]. 2009;(48):10681–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-71549136812&doi=10.1039%252fb918871c&partnerID=40&md5=cf1cab661138e82ea6c40d5bdd82b4ef

50.

Kasherman Y, Sturup S, Gibson D. Is glutathione the major cellular target of cisplatin? A study of the interactions of cisplatin with cancer cell extracts. Journal of Medicinal Chemistry [Internet]. 2009;52(14):4319–28. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-67650723128&doi=10.1021%252fjm900138u&partnerID=40&md5=8b50b566a3570c549778967e0054bda6

51.

Kasherman Y, Sturup S, Gibson D. Trans labilization of am(m)ine ligands from platinum(II) complexes by cancer cell extracts. Journal of Biological Inorganic Chemistry [Internet]. 2009;14(3):387–99. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-62049083507&doi=10.1007%252fs00775-008-0456-6&partnerID=40&md5=eff2676e3d9df25f6e90f47e98597636

52.

Gabbiani C, Casini A, Mastrobuoni G, Kirshenbaum N, Moshel O, Pieraccini G, et al. Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis. Journal of Biological Inorganic Chemistry [Internet]. 2008;13(5):755–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-44549084093&doi=10.1007%252fs00775-008-0361-z&partnerID=40&md5=6ea9f0f0cfda7373b22c961fd13cd506

53.

Halámiková A, Heringová P, Kašpárková J, Intini FP, Natile G, Nemirovski A, et al. Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine. Journal of Inorganic Biochemistry [Internet]. 2008;102(5–6):1077–89. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-41949095467&doi=10.1016%252fj.jinorgbio.2007.12.015&partnerID=40&md5=fb928ce3e57257b1512814911673dd05

54.

Narang S, Gibson D, Wasan AD, Ross EL, Michna E, Nedeljkovic SS, et al. Efficacy of Dronabinol as an Adjuvant Treatment for Chronic Pain Patients on Opioid Therapy. Journal of Pain [Internet]. 2008;9(3):254–64. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-39549091694&doi=10.1016%252fj.jpain.2007.10.018&partnerID=40&md5=2009443909929bb9e8033fd788867ec4

55.

Nemirovski A, Kasherman Y, Tzaraf Y, Gibson D. Reduction of cis,trans,cis-[PtCl2(OCOCH3) 2(NH3)2] by aqueous extracts of cancer cells. Journal of Medicinal Chemistry [Internet]. 2007;50(23):5554–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-36148961569&doi=10.1021%252fjm070740j&partnerID=40&md5=a6bb1779a31215f92019fd3d39bb1f59

56.

Brabec V, Christofis P, Slámová M, Kostrhunová H, Nováková O, Najajreh Y, et al. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[PtCl2(NH3)2(piperazine)]. Biochemical Pharmacology [Internet]. 2007;73(12):1887–900. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-34247611426&doi=10.1016%252fj.bcp.2007.03.003&partnerID=40&md5=f517a560f67b32c33d3c4ce75ff5c13d

57.

Najajreh Y, Khazanov E, Jawbry S, Ardeli-Tzaraf Y, Perez JM, Kasparkova J, et al. Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies. Journal of Medicinal Chemistry [Internet]. 2006;49(15):4665–73. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746765017&doi=10.1021%252fjm060237r&partnerID=40&md5=89622aedd1c8050c19405d20db51dc9f

58.

Najajreh Y, Ardeli-Tzaraf Y, Kasparkova J, Heringova P, Prilutski D, Balter L, et al. Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles. Journal of Medicinal Chemistry [Internet]. 2006;49(15):4674–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746714979&doi=10.1021%252fjm060238j&partnerID=40&md5=f7536051bce0e7bf412e0447ff9d76ac

59.

Anzellotti A, Stefan S, Gibson D, Farrell N. Donor atom preferences in substitution reactions of trans-platinum mononucleobase compounds: Implications for DNA-protein selectivity. Inorganica Chimica Acta [Internet]. 2006;359(9):3014–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646510074&doi=10.1016%252fj.ica.2005.12.060&partnerID=40&md5=b958f4f9a5597611d07692e2ef9f6372

60.

Gibson D, Kasherman Y, Kowarski D, Freikman I. The trans labilization of cis-[PtCl2(13CH 3NH2)2] by glutathione can be monitored at physiological pH by [1H,13C] HSQC NMR. Journal of Biological Inorganic Chemistry [Internet]. 2006;11(2):179–88. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-32444433747&doi=10.1007%252fs00775-005-0064-7&partnerID=40&md5=72b7be9ba0cb5ab9f4879d7c72a5bee8

61.

Najajreh Y, Kasparkova J, Marini V, Gibson D, Brabec V. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand. Journal of Biological Inorganic Chemistry [Internet]. 2005;10(7):722–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-27744569946&doi=10.1007%252fs00775-005-0024-2&partnerID=40&md5=b15b48d6431bf175ac0d579113121a68

62.

Jawbry S, Freikman I, Najajreh Y, Perez JM, Gibson D. Preparation, cytotoxicity and interactions with nucleophiles of three isomeric transplatinum complexes containing methylpiperidine ligands. Journal of Inorganic Biochemistry [Internet]. 2005;99(10):1983–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-26044447448&doi=10.1016%252fj.jinorgbio.2005.06.011&partnerID=40&md5=d8042c65c3725966c885c27bdf0e04c9

63.

Sobol E, Yagen B, Winkler I, Britzi M, Gibson D, Bialer M. Pharmacokinetics and metabolism of a new potent antiepileptic drug, 2,2,3,3-tetramethycyclopropanecarbonylurea, in rats. Drug Metabolism and Disposition [Internet]. 2005;33(10):1538–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-24944565232&doi=10.1124%252fdmd.105.005637&partnerID=40&md5=eda95308b728dfb16b506c9f8577b241

64.

Najajreh Y, Prilutski D, Ardeli-Tzaraf Y, Perez JM, Khazanov E, Barenholz Y, et al. Structure and unique interactions with DNA of a cationic Trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand. Angewandte Chemie - International Edition [Internet]. 2005;44(19):2885–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-18844372028&doi=10.1002%252fanie.200462389&partnerID=40&md5=236a00c0db9df2bb4a1a0fbfb71fe50b

65.

Balter L, Gibson D. Mass spectrometric studies of the formation and reactivity of trans-[PtCl2(Am)(piperidinopiperidine)]·HCl complexes with ubiquitin. Rapid Communications in Mass Spectrometry [Internet]. 2005;19(24):3666–72. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-29144445367&doi=10.1002%252frcm.2244&partnerID=40&md5=f769097d533ef9c3c9f43203b131418a

66.

Kogan NM, Rabinowitz R, Levi P, Gibson D, Sandor P, Schlesinger M, et al. Synthesis and antitumor activity of quinonoid derivatives of cannabinoids. Journal of Medicinal Chemistry [Internet]. 2004;47(15):3800–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3142618434&doi=10.1021%252fjm040042o&partnerID=40&md5=72c0dcd4667700cde4e5e69d4c434288

67.

Aronov O, Horowitz AT, Gabizon A, Fuertes MA, Pérez JM, Gibson D. Nuclear localization signal-targeted poly(ethylene glycol) conjugates as potential carriers and nuclear localizing agents for carboplatin analogues. Bioconjugate Chemistry [Internet]. 2004;15(4):814–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242745979&doi=10.1021%252fbc0499331&partnerID=40&md5=8c84658897acdd26b638863507576648

68.

Kasparkova J, Novakova O, Marini V, Najajreh Y, Gibson D, Perez JM, et al. Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action. Journal of Biological Chemistry [Internet]. 2003;278(48):47516–25. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0347481385&doi=10.1074%252fjbc.M304720200&partnerID=40&md5=ad545908637c8e7023e45266b106ef72

69.

Kasparkova J, Novakova O, Najajreh Y, Gibson D, Perez JM, Brabec V. Effects of a Piperidine Ligand on DNA Modification by Antitumor Cisplatin Analogues. Chemical Research in Toxicology [Internet]. 2003;16(11):1424–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0345283279&doi=10.1021%252ftx034128g&partnerID=40&md5=fa1f5c346ad802a78b58278e4615fd53

70.

Kasparkova J, Marini V, Najajreh Y, Gibson D, Brabec V. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines. Biochemistry [Internet]. 2003;42(20):6321–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037845097&doi=10.1021%252fbi0342315&partnerID=40&md5=8c6b0b86cb0c65941434f18cf8891988

71.

Aronov O, Horowitz AT, Gabizon A, Gibson D. Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjugate Chemistry [Internet]. 2003;14(3):563–74. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0038246506&doi=10.1021%252fbc025642l&partnerID=40&md5=c6f352a65571d83ed06293ef6d709917

72.

Najajreh Y, Peleg-Shulman T, Moshel O, Farrel N, Gibson D. Ligand effects on the binding of cis- and trans-[PtCl2Am1Am2 to proteins. Journal of Biological Inorganic Chemistry [Internet]. 2003;8(1–2):167–75. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037260410&doi=10.1007%252fs00775-002-0402-y&partnerID=40&md5=4f67547464699b154e344c84920d5e2d

73.

Najajreh Y, Perez JM, Navarro-Ranninger C, Gibson D. Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines. Journal of Medicinal Chemistry [Internet]. 2002;45(24):5189–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037153219&doi=10.1021%252fjm0201969&partnerID=40&md5=d8182b197c540841a9941c8334fbde40

74.

Khazanov E, Barenholz Y, Gibson D, Najajreh Y. Novel apoptosis-inducing trans-platinum piperidine derivatives: Synthesis and biological characterization. Journal of Medicinal Chemistry [Internet]. 2002;45(24):5196–204. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037153213&doi=10.1021%252fjm020817y&partnerID=40&md5=4a12ed09da74abb818b28f44c4f70882

75.

Peleg-Shulman T, Najajreh Y, Gibson D. Interactions of cisplatin and transplatin with proteins.Comparison of binding kinetics, binding sites and reactivity of the Pt-protein adducts of cisplatin and transplatin towards biological nucleophiles. Journal of Inorganic Biochemistry [Internet]. 2002;91(1):306–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037173594&doi=10.1016%2fS0162-0134%2802%2900362-8&partnerID=40&md5=bef9a366b1bca25a2f11d79f9102f179

76.

Gibson D. Drug-DNA interactions and novel drug design. Pharmacogenomics Journal [Internet]. 2002;2(5):275–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036448484&doi=10.1038%252fsj.tpj.6500133&partnerID=40&md5=8df5f59e59e5e481e247d40a99c171f7

77.

Peleg-Shulman T, Gibson D. Cisplatin-protein adducts are efficiently removed by glutathione but not by 5′-guanosine monophosphate. Journal of the American Chemical Society [Internet]. 2001;123(13):3171–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034822680&doi=10.1021%252fja005854y&partnerID=40&md5=3c98318137041380125682e240fe6d2b

78.

Peleg-Shulman T, Gibson D, Cohen R, Abra R, Barenholz Y. Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance. Biochimica et Biophysica Acta - Biomembranes [Internet]. 2001;1510(1–2):278–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035830628&doi=10.1016%2fS0005-2736%2800%2900359-X&partnerID=40&md5=3a090a2a183005d41f9c8dfd7af1bcbd

79.

Peleg-Shulman T, Katzhendler J, Gibson D. Effects of monofunctional platinum binding on the thermal stability and conformation of a self-complementary 22-mer. Journal of Inorganic Biochemistry [Internet]. 2000;81(4):313–23. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034307084&doi=10.1016%2fS0162-0134%2800%2900120-3&partnerID=40&md5=d99b162868e87a34ab691b37da968c51

80.

Gibson D, Costello CE. Mass spectrometry of biomolecules. Separation Science and Technology [Internet]. 2000;2(C):299–327. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79151473130&doi=10.1016%2fS0149-6395%2800%2980053-7&partnerID=40&md5=c25c65b8ad1b4cae7aa76e265e15b12a

81.

Gibson D, Costello CE. A mass spectral study of the binding of the anticancer drug cisplatin to ubiquitin. European Journal of Mass Spectrometry [Internet]. 1999;5(6):501–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001165693&doi=10.1255%252fejms.314&partnerID=40&md5=236f80b802f086ea9459ee63eb7a3f27

82.

Bauer C, Peleg-Shulman T, Gibson D, Wang AHJ. Monofunctional platinum amine complexes destabilize DNA significantly. European Journal of Biochemistry [Internet]. 1998;256(2):253–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031718788&doi=10.1046%252fj.1432-1327.1998.2560253.x&partnerID=40&md5=8c9f5efa092e8f7fcc46ea4a879ce4e7

83.

Ferreira ADQ, Bino A, Gibson D. Preparation, Structure and Stability of cis-Cr(phen)2[OP(O)(OC6H5)2](H 2O)2+ as a Model for Cr(III)-DNA Adducts. Inorganic Chemistry [Internet]. 1998;37(26):6560–1. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000681834&doi=10.1021%252fic981095x&partnerID=40&md5=3556b9808237ec74b6c53a8e74a07eec

84.

Ferreira ADQ, Bino A, Gibson D. Novel carboplatin analogs containing flexible and potentially intercalating ligands: Preparation and X-ray crystal structures of di-2-pyridyl ketone cyclobutanedicarboxylate platinum(II) and of 2,3-bis(2-pyridyl)pyrazine cyclobutane dicarboxylate platinum(II). Inorganica Chimica Acta [Internet]. 1997;265(1-2 PART II):155–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000033441&doi=10.1016%2fs0020-1693%2897%2905742-3&partnerID=40&md5=69ea68c1742b2a4d11d4678122c49fb1

85.

Gibson D, Binyamin I, Haj M, Ringel I, Ramu A, Katzhendler J. Anthraquinone intercalators as carrier molecules for second-generation platinum anticancer drugs. European Journal of Medicinal Chemistry [Internet]. 1997;32(10):823–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030736636&doi=10.1016%2fS0223-5234%2899%2980068-3&partnerID=40&md5=696872320996f3754d2619a723c4823b

86.

Breuer E, Zaher H, Tashma Z, Gibson D. Acylphosphonamidates and α-hydroxyiminophosphonamidates. Synthesis of N-acylphosphordiamidates by Beckmann rearrangement. Crystal structure of (E)-α-hydroxyiminobenzyl-1-pyrrolidinylphosphinate. Heteroatom Chemistry [Internet]. 1996;7(6):515–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0010785013&doi=10.1002%2f%28SICI%291098-1071%28199611%297%3a6%3c515%3a%3aAID-HC13%3e3.0.CO%3b2-T&partnerID=40&md5=3b78a76bb27f757129a5790426165cc5

87.

Gibson D, Mansur N, Gean KF. Preparation, characterization, and antitumor properties of cis-PtCl2 complexes linked to anthraquinones through position number 2. Journal of Inorganic Biochemistry [Internet]. 1995;58(2):79–88. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028951468&doi=10.1016%2f0162-0134%2894%2900103-H&partnerID=40&md5=19f7eb2421da3d8d7123976e4883b8d0

88.

Doungdee P, Sarel S, Ringel I, Gibson D, Wongvisetsirikul N, Avramovici-Grisaru S. Iron chelators of the pyridoxal 2-pyridyl hydrazone class. part III.1 Ionisation and conformational characteristics of the ligands. Heterocycles [Internet]. 1995;40(1):241–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745484074&doi=10.3987%252fcom-94-s16&partnerID=40&md5=fa6928b5a8eefe44f58c81f0b8a79941

89.

Arvanitis GM, Gibson D, Emge TJ, Berman HM. Platinum(II) triamine complexes: cis-[PtCl(NH3)2(C10H13N5O5)]NO3.2H2O and [PtCl(C2H8N2)(C4H6N2)]NO3. Acta crystallographica Section C, Crystal structure communications [Internet]. 1994;50 ( Pt 8):1217–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028774141&doi=10.1107%252fs010827019301073x&partnerID=40&md5=4af3ff1fc031871afaf8abd6b0a4041f

90.

Gibson D, Arvanitis GM, Berman HM. Ternary Pt(II)-amino acid-nucleotide complexes: kinetics of formation. Inorganica Chimica Acta [Internet]. 1994;218(1–2):11–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0002226105&doi=10.1016%2f0020-1693%2894%2903797-3&partnerID=40&md5=fbe10b380a46f0b96be7e3c526a921fa

91.

Rosenfeld A, Blum J, Gibson D, Ramu A. Preparation, characterization and antileukemic properties of diaminemalonatoplatinum(II) complexes tethered to ferrocene. Inorganica Chimica Acta [Internet]. 1992;201(2):219–21. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-4243690028&doi=10.1016%2fS0020-1693%2800%2985336-0&partnerID=40&md5=9ed0e9b5981acc503fdf055826e6e061

92.

Devane WA, Hanuš L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science [Internet]. 1992;258(5090):1946–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027078685&doi=10.1126%252fscience.1470919&partnerID=40&md5=dc9c5517bc0458f9fa1d18dd6fd09b57

93.

Breuer E, Safadi M, Chorev M, Gibson D. Evaluation of the n-phthaloyl moiety as protecting group in aminoacylphosphonic derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements [Internet]. 1991;60(3–4):239–46. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-80051950001&doi=10.1080%252f10426509108036787&partnerID=40&md5=1670ff25842232a40e70f3ed824301e7

94.

Gibson D, Gean KF, Ben-Shoshan R, Katzhendler J, Ramu A, Ringel I. Preparation, Characterization, and Anticancer Activity of a Series of cis-PtCl2 Complexes Linked to Anthraquinone Intercalators. Journal of Medicinal Chemistry [Internet]. 1991;34(1):414–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026087006&doi=10.1021%252fjm00105a063&partnerID=40&md5=eeff68de4db9bcff08c80b4337971ee9

95.

Gean K, Ben-Shoshan R, Ramu A, Ringel I, Katzhendler J, Gibson D. Preparation, characterization and the anticancer activity of a novel series of triaminemonochloroplatinum(II) cations linked to anthraquinone intercalators. European Journal of Medicinal Chemistry [Internet]. 1991;26(6):593–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026003002&doi=10.1016%2f0223-5234%2891%2990193-Q&partnerID=40&md5=be3168f16ef05177d9e5a4567320ab0c

96.

Schlossman A, Gibson D, Breuer E. Rearrangement and fragmentation reactions of α-hydroxyiminophoshinates. On the nature of the metaphosphonate intermediate involved in phosphonylations by α-hydroxyiminophosphinate. Phosphorus, Sulfur, and Silicon and the Related Elements [Internet]. 1990;49–50(1–4):81–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84972808996&doi=10.1080%252f10426509008038912&partnerID=40&md5=8b0cc137878ac1c1e506b1af5a184cc5

97.

Breuer E, Schlossman A, Safadi M, Gibson D, Chorev M, Leader H. Stereoselectivity in fragmentation and rearrangement of α-hydroxyimino-phosphinates and -phosphonates. A synthetic approach to acylphosphon- and phosphor-amidates. Crystal structures of methyl (E)-α-hydroxyimino-benzylphenylphosphinate and methyl benzoylphenylphosphonamidate. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1990;(12):3263–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049073703&doi=10.1039%252fp19900003263&partnerID=40&md5=30d7e0e12d0ad78d84ab8ad6c6d42473

98.

Gibson D, Rosenfeld A, Apfelbaum H, Blum J. Multinuclear (195Pt, 15N, 13C) NMR studies of the reactions between cis-diaminediaquaplatinum(ii) complexes and aminomalonate. Inorganic Chemistry [Internet]. 1990;29(25):5125–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0346964901&doi=10.1021%252fic00350a021&partnerID=40&md5=0042276f3449dfbf602b45bc00cc52c4

99.

Breuer E, Safadi M, Chorev M, Gibson D. Novel Amino Acid Derivatives. Preparation and Properties of Aminoacylphosphonates and Amino Hydroxyimino Phosphonates. Journal of Organic Chemistry [Internet]. 1990;55(25):6147–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025641566&doi=10.1021%252fjo00312a021&partnerID=40&md5=d0b26be56383bd986bba3fc03c6de107

100.

Coll M, Sherman SE, Gibson D, Lippard SJ, Wang AHJ. Molecular structure of the complex formed between the anticancer drug cisplatin and d(PGpG): C2221 crystal form. Journal of Biomolecular Structure and Dynamics [Internet]. 1990;8(2):315–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025110405&doi=10.1080%252f07391102.1990.10507808&partnerID=40&md5=9bdfc8b6e2b06d992c8f3a353765dc68

101.

Breuer E, Karaman R, Goldblum A, Gibson D, Leader H, Potter BVL, et al. Erratum: α-Oxyiminophosphonates: Chemical and physical properties. Reactions, theoretical calculations and crystal structures of (E)- And (Z)-dimethyl α-Hydroxyiminobenzylphosphonates (Journal of the Chemical Society, Perkin Transactions 1 (1988) 3047). Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1989;(7):1367. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049087653&partnerID=40&md5=67463a0379af1984593034f865618515

102.

Katzhendler J, Ringel I, Goldblum A, Gibson D, Tashma Z. Conformational studies of substituted five-membered cyclic carbonates and related compounds by MNDO, and the X-ray crystal structure of 4-chlorophenyloxymethyl-1,3-dioxolan-2-one. Journal of the Chemical Society, Perkin Transactions 2 [Internet]. 1989;(11):1729–39. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049078411&partnerID=40&md5=2437002a0b4d9628d705147d4611be7b

103.

Breuer E, Karaman R, Gibson D, Goldblum A. Structure and reactivity of 2-hydroxyiminobenzyl-2-oxo-4,4,5,5-tetramethyl[1,3,2]dioxaphospholanes. Phosphorus, Sulfur, and Silicon and the Related Elements [Internet]. 1989;41(3–4):433–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973065376&doi=10.1080%252f10426508908039733&partnerID=40&md5=7232f27d3a01e146e4ee946654dff9ba

104.

Gibson D, Karaman R. Metal complexes of α-hydroxyiminophosphonic acid derivatives. Preparation and crystal structures of calcium and cadmium complexes of methyl (E)-α-hydroxyiminobenzylphosphonate. Journal of the Chemical Society, Dalton Transactions [Internet]. 1989;(10):1911–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049077706&doi=10.1039%252fDT9890001911&partnerID=40&md5=cbb666e02db18213e6ee7ee8219f0d9f

105.

Katzhendler J, Karaman R, Gibson D, Breuer E, Leader H. Fragmentation of methyl hydrogen α-hydroxyiminophosphonates to monomeric methyl metaphosphate: Stereochemistry and mechanism. Journal of the Chemical Society, Perkin Transactions 2 [Internet]. 1989;(6):589–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049074347&doi=10.1039%252fp29890000589&partnerID=40&md5=48919b7533f414bf8e1d01bd3f6783fd

106.

Gibson D, Karaman R. Metal complexes of α-hydroxyimino phosphonic acid derivatives. Separation of the E and Z isomers by metal chelation and the preparation and characterization of copper bis[-(α-(hydroxyimino)benzyl)phosphonate]-water. Inorganic Chemistry [Internet]. 1989;28(10):1928–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0009492533&doi=10.1021%252fic00309a031&partnerID=40&md5=78d34159d2791bdd2964b444bce2bd4d

107.

Ringel I, Bakshi O, Mellado W, Ramu A, Gibson D, Katzhendler J. N-Alkyl colchiceineamides: their inhibition of GTP or taxol-induced assembly of tubulin. Biochemical Pharmacology [Internet]. 1988;37(12):2487–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023922647&doi=10.1016%2f0006-2952%2888%2990380-2&partnerID=40&md5=38e961657809b5cecc01c5e91064c71b

108.

Breuer E, Karaman R, Goldblum A, Gibson D, Leader H, Potter BVL, et al. α-Oxyiminophosphonates: Chemical and physical properties. Reactions, theoretical calculations, and x-ray crystal structures of (E) and (Z)-dimethyl α-hydroxyiminobenzylphosphonates. Journal of the Chemical Society, Perkin Transactions 1 [Internet]. 1988;(11):3047–57. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049088990&doi=10.1039%252fp19880003047&partnerID=40&md5=3ae53626e54143b0759e11bc5d9f2396

109.

Breuer E, Karaman R, Gibson D, Leader H, Goldblum A. α-hydroxyiminophosphonic acids. New types of phosphorylating agents through monomeric metaphosphate. Journal of the Chemical Society, Chemical Communications [Internet]. 1988;(7):504–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049087674&doi=10.1039%252fC39880000504&partnerID=40&md5=4511ee3e878146cf488b1396a9ed45e8

110.

Kitov S, Ben-Shoshan R, Ringel I, Gibson D, Katzhendler J. The effect of cis-platin analogues derived from aminoalkylaminoanthraquinones on DNA cleavage: an electron microscopy study. European Journal of Medicinal Chemistry [Internet]. 1988;23(4):381–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023772990&doi=10.1016%2f0223-5234%2888%2990213-9&partnerID=40&md5=f8a5aab82509339722dbf2b109e4c4d4

111.

Sherman SE, Gibson D, Lippard SJ, Wang AHJ. Crystal and Molecular Structure of cis-[Pt(NH3)2d(pGpG)], the Principal Adduct Formed by cis-Diamminedichloroplatinum(II) with DNA. Journal of the American Chemical Society [Internet]. 1988;110(22):7368–81. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023709418&doi=10.1021%252fja00230a017&partnerID=40&md5=207698ec3de2a13699d2f4ed1575dc10

112.

Villacorta GM, Gibson D, Williams ID, Whang E, Lippard SJ. Alkyne-Bridged Dicopper(I) Complexes of the Tropocoronand Macrocycles. Organometallics [Internet]. 1987;6(11):2426–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001680381&doi=10.1021%252fom00154a025&partnerID=40&md5=cd32586a1ca72a7df9ca621902acd1f7

113.

Gibson D, Lippard SJ. Synthesis and NMR Structural Studies of the Adduct of trans -Diamminedichloroplatinum(II) with the DNA Fragment d(GpCpG). Inorganic Chemistry [Internet]. 1987;26(14):2275–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0005473225&doi=10.1021%252fic00261a022&partnerID=40&md5=4e6af718308ce3a593831d24f53e039c

114.

Gibson D, Lippard SJ. Preparation and Structural Characterization of a Novel Hexanuclear Complex of Platinum(II) with 2-Aminoethanethiolate. Inorganic Chemistry [Internet]. 1986;25(2):219–22. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022577842&doi=10.1021%252fic00222a025&partnerID=40&md5=7905f13d91e185a423a960c183c18ca2

115.

Bino A, Gibson D. Tritungsten(IV) cluster compounds with hydroxo ligands. Preparation and structure of [W3O2(O2CCH3)6(H2O)(OH)2]·16H2O and [W3O2(O2CCH3)6(H2O)(OH)2]·KBr·15H2O. Inorganica Chimica Acta [Internet]. 1985;104(3):155–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-46549094439&doi=10.1016%2fS0020-1693%2800%2986765-1&partnerID=40&md5=9b45a67db16f1f0caf461250b96e5bcd

116.

Shamir J, Luski S, Bino A, Cohen S, Gibson D. Tetrachloro-phosphonium salts of hexachloro antimonate and niobate and their solvates. Preparation and structure by vibrational spectroscopy and x-ray crystallography. Inorganica Chimica Acta [Internet]. 1985;104(2):91–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-46549090588&doi=10.1016%2fS0020-1693%2800%2986422-1&partnerID=40&md5=abf4ed7d8a2110300aa76b437c7373f8

117.

Shamir J, Luski S, Bino A, Cohen S, Gibson D. Reactions of Phosphorus Pentachloride with Tin Tetrachloride. Tetrachlorophosphonium Salts with SnCl62-, Sn2Cl102-, and SnCl5- Anions: Preparation and Structure by Vibrational Spectra and X-ray Crystallography. Inorganic Chemistry [Internet]. 1985;24(14):2301–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001761581&doi=10.1021%252fic00208a035&partnerID=40&md5=302feea8f6a8cdc25947c6f726b78038

118.

Bino A, Gibson D. Hydrogen oxide (H3O2) bridge formation in trinuclear metal cluster systems. The structure of [W3O2(O2CCH3)6(H2O)(H3O2)] NCS·H2O. Inorganica Chimica Acta [Internet]. 1985;101(1):L9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-46549091775&doi=10.1016%2fS0020-1693%2800%2985615-7&partnerID=40&md5=55fefad91a24f1b8845f23d57af43d51

119.

Benory E, Bino A, Gibson D, Cotton FA, Dori Z. Oxalato complexes of the trinuclear aquo ion of molybdenum(IV), [Mo3O4]4+. Inorganica Chimica Acta [Internet]. 1985;99(2):137–42. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000340631&doi=10.1016%2fS0020-1693%2800%2987959-1&partnerID=40&md5=668f42e02b59d2e5cdcc3d4df881609e

120.

Sherman SE, Gibson D, Wang AHJ, Lippard SJ. X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2d(pGpG)]. Science [Internet]. 1985;230(4724):412–7. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022345333&doi=10.1126%252fscience.4048939&partnerID=40&md5=28cc1e10f1683c9f562fb6efd49f6d9a

121.

Villacorta GM, Gibson D, Williams ID, Lippard SJ. Dicopper(I) Tropocoronands: Synthesis, X-ray Crystal Structure, and Spectral Properties of Neutral Binuclear Copper(I) Complexes Bridged by Symmetrically Substituted Alkynes. Journal of the American Chemical Society [Internet]. 1985;107(23):6732–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0011652660&doi=10.1021%252fja00309a064&partnerID=40&md5=49dec8cc0623fb8bac6130e1a1b62d1a

122.

Feinstein-Jaffe I, Gibson D, Lippard SJ, Schrock RR, Spool A. A Molecule Containing the OWOWO Unit. Synthesis, Structure, and Spectroscopy of W2O3(CH2CMe3)6. Journal of the American Chemical Society [Internet]. 1984;106(21):6305–10. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0006109149&doi=10.1021%252fja00333a032&partnerID=40&md5=55ac5f0c11ad3a6371263ee172a3cded

123.

Bino A, Gibson D. The Hydrogen Oxide Bridging Ligand (H302-). 2. Effect of the Hydrogen Ion Concentration. Inorganic Chemistry [Internet]. 1984;23(1):109–15. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0001414351&doi=10.1021%252fic00169a023&partnerID=40&md5=c01e05f75254b5e8ef6c129bac30c656

124.

Bino A, Gibson D. Trinuclear Mo(IV) cluster ion with a propylidyne cap. Inorganica Chimica Acta [Internet]. 1982;65(C):L37–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-24444463675&doi=10.1016%2fS0020-1693%2800%2993486-8&partnerID=40&md5=e233a473b629ed14d287deda277959ca

125.

Bino A, Gibson D. The Hydrogen Oxide Bridging Ligand (H3O2−). 1. Dimerization and Polymerization of Hydrolyzed Trinuclear Metal Cluster Ions. Journal of the American Chemical Society [Internet]. 1982;104(16):4383–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000127326&doi=10.1021%252fja00380a012&partnerID=40&md5=44fe4a90dcaa922f8d4be7c1f780455d

126.

Bino A, Gibson D. A New Bridging Ligand, the Hydrogen Oxide Ion (H302−). Journal of the American Chemical Society [Internet]. 1981;103(22):6741–2. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000507060&doi=10.1021%252fja00412a035&partnerID=40&md5=4ee0f64a5a975e306f7f95c5f9836225

127.

Bino A, Gibson D. A New, Convenient, and Efficient Route to Dimolybdenum(II) Compounds from MoO3. Journal of the American Chemical Society [Internet]. 1980;102(12):4277–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0442271391&doi=10.1021%252fja00532a058&partnerID=40&md5=fbb919c7af8c28dba3ab9a64ff6bca1a