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School of Pharmacy : Ringel Israel

Researchers

 Last updated Septmber 2023 - School of Pharmacy

List of Publications

1.

Shemesh A, Ghareeb H, Dharan R, Levi-Kalisman Y, Metanis N, Ringel I, et al. Effect of tubulin self-association on GTP hydrolysis and nucleotide exchange reactions. Biochimica et Biophysica Acta - Proteins and Proteomics [Internet]. 2023;1871(2). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85143617886&doi=10.1016%252fj.bbapap.2022.140869&partnerID=40&md5=9265da1d712e3e4b2a990da53652593b

2.

Shemesh A, Dharan N, Ginsburg A, Dharan R, Levi-Kalisman Y, Ringel I, et al. Mechanism of the Initial Tubulin Nucleation Phase. Journal of Physical Chemistry Letters [Internet]. 2022;13(41):9725–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140415950&doi=10.1021%252facs.jpclett.2c02619&partnerID=40&md5=deb2fcb5f71820717e464ac201125a32

3.

Shemesh A, Ginsburg A, Dharan R, Levi-Kalisman Y, Ringel I, Raviv U. Mechanism of Tubulin Oligomers and Single-Ring Disassembly Catastrophe. Journal of Physical Chemistry Letters [Internet]. 2022;13:5246–52. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85140814462&doi=10.1021%252facs.jpclett.2c00947&partnerID=40&md5=83942c74f407aa7a7b6caa6352b8e8e9

4.

Shemesh A, Ginsburg A, Dharan R, Levi-Kalisman Y, Ringel I, Raviv U. Structure and Energetics of GTP- And GDP-Tubulin Isodesmic Self-Association. ACS Chemical Biology [Internet]. 2021;16(11):2212–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118204684&doi=10.1021%252facschembio.1c00369&partnerID=40&md5=e03d3798da1afdfc447f220739c902c3

5.

Dharan R, Shemesh A, Millgram A, Zalk R, Frank GA, Levi-Kalisman Y, et al. Hierarchical Assembly Pathways of Spermine-Induced Tubulin Conical-Spiral Architectures. ACS Nano [Internet]. 2021;15(5):8836–47. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106480862&doi=10.1021%252facsnano.1c01374&partnerID=40&md5=96eb9f34acf732157812dfcda6caf612

6.

Shemesh A, Ginsburg A, Levi-Kalisman Y, Ringel I, Raviv U. Structure, Assembly, and Disassembly of Tubulin Single Rings. Biochemistry [Internet]. 2018;57(43):6153–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054839693&doi=10.1021%252facs.biochem.8b00560&partnerID=40&md5=83a3703d9005ebfa64ac032aba363e72

7.

Ginsburg A, Shemesh A, Millgram A, Dharan R, Levi-Kalisman Y, Ringel I, et al. Structure of Dynamic, Taxol-Stabilized, and GMPPCP-Stabilized Microtubule. Journal of Physical Chemistry B [Internet]. 2017;121(36):8427–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029570651&doi=10.1021%252facs.jpcb.7b01057&partnerID=40&md5=4a6ab4b84751fe350d9ce744d60cca3c

8.

Ginsburg A, Ben-Nun T, Asor R, Shemesh A, Ringel I, Raviv U. Reciprocal Grids: A Hierarchical Algorithm for Computing Solution X-ray Scattering Curves from Supramolecular Complexes at High Resolution. Journal of Chemical Information and Modeling [Internet]. 2016;56(8):1518–27. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983479194&doi=10.1021%252facs.jcim.6b00159&partnerID=40&md5=19e0c3a48464d30deca2c145cd608742

9.

Abramov Y, Carmi S, Anteby SO, Ringel I. Characterization of ovarian cancer cell metabolism and response to chemotherapy by 31P magnetic resonance spectroscopy. Oncology Research [Internet]. 2013;20(11):529–36. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84886923818&doi=10.3727%252f096504013X13747716581372&partnerID=40&md5=9d06b45420d61356127b34f676200d44

10.

Abramov Y, Carmi S, Anteby SO, Ringel I. Ex vivo 1H and 31P magnetic resonance spectroscopy as a means for tumor characterization in ovarian cancer patients. Oncology Reports [Internet]. 2013;29(1):321–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872867449&doi=10.3892%252for.2012.2071&partnerID=40&md5=87a01cc4ddd43bddf5207d02292e41f0

11.

Freikman I, Ringel I, Fibach E. Shedding of phosphatidylserine from developing erythroid cells involves microtubule depolymerization and affects membrane lipid composition. Journal of Membrane Biology [Internet]. 2012;245(12):779–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871274666&doi=10.1007%252fs00232-012-9478-7&partnerID=40&md5=52a66026029b00c62aee1323257e2540

12.

Abramov Y, Carmi S, Cohen JS, Anteby SO, Ringel I. 31P-Magnetic resonance spectra of ovarian cancer cells exposed to chemotherapy within a three-dimensional Matrigel construct. Oncology Reports [Internet]. 2012;28(2):735–41. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863464639&doi=10.3892%252for.2012.1810&partnerID=40&md5=eb1559f4cd576aefb4a2eb98f952c5a8

13.

Kolevzon N, Kuflik U, Shmuel M, Benhamron S, Ringel I, Yavin E. Multiple triphenylphosphonium cations as a platform for the delivery of a pro-apoptotic peptide. Pharmaceutical Research [Internet]. 2011;28(11):2780–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856217682&doi=10.1007%252fs11095-011-0494-6&partnerID=40&md5=26e1da4b78358681fd0db6edfc57df09

14.

Freikman I, Ringel I, Fibach E. Oxidative stress-induced membrane shedding from RBCs is Ca flux-mediated and affects membrane lipid composition. Journal of Membrane Biology [Internet]. 2011;240(2):73–82. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79953682511&doi=10.1007%252fs00232-011-9345-y&partnerID=40&md5=eaf018c5b0072972d8771341d757aacb

15.

Freikman I, Amer J, Ringel I, Fibach E. A flow cytometry approach for quantitative analysis of cellular phosphatidylserine distribution and shedding. Analytical Biochemistry [Internet]. 2009;393(1):111–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-67650957548&doi=10.1016%252fj.ab.2009.06.011&partnerID=40&md5=edc3b3b71d638cc3dc773c493952cabf

16.

Abu-Gosh SE, Kolvazon N, Tirosh B, Ringel I, Yavin E. Multiple triphenylphosphonium cations shuttle a hydrophilic peptide into mitochondria. Molecular Pharmaceutics [Internet]. 2009;6(4):1138–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-68249112286&doi=10.1021%252fmp900032r&partnerID=40&md5=d782b5c016684debc149915187b8c7a1

17.

Goldfinger M, Laviad EL, Hadar R, Shmuel M, Dagan A, Park H, et al. De novo ceramide synthesis is required for n-linked glycosylation in plasma cells. Journal of Immunology [Internet]. 2009;182(11):7038–47. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-67449146868&doi=10.4049%252fjimmunol.0802990&partnerID=40&md5=72e412283daa50793a39e6d6e94c2d89

18.

Ringel I, Lecht S, Sterin M, Lelkes PI, Lazarovici P. 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: II. The effect of anti-inflammatory drugs on phosphometabolite levels. Endothelium: Journal of Endothelial Cell Research [Internet]. 2008;15(5–6):299–307. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-60549104849&doi=10.1080%252f10623320802487874&partnerID=40&md5=169070ef18076ba9806178dedff56667

19.

Sterin M, Ringel I, Lecht S, Lelkes PI, Lazarovici P. 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: I. The effect of glial cells and valporic acid on phosphometabolite levels. Endothelium: Journal of Endothelial Cell Research [Internet]. 2008;15(5–6):288–98. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-60549091627&doi=10.1080%252f10623320802487841&partnerID=40&md5=b0b61173006076fa163468e4de53ff0c

20.

Freikman I, Amer J, Cohen JS, Ringel I, Fibach E. Oxidative stress causes membrane phospholipid rearrangement and shedding from RBC membranes-An NMR study. Biochimica et Biophysica Acta - Biomembranes [Internet]. 2008;1778(10):2388–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-52049090128&doi=10.1016%252fj.bbamem.2008.06.008&partnerID=40&md5=ba72086fe0cee503e3781f4c6b5988f9

21.

Muhlrad A, Ringel I, Pavlov D, Peyser TM, Reisler E. Antagonistic effects of cofilin, beryllium fluoride complex, and phalloidin on subdomain 2 and nucleotide-binding cleft in F-actin. Biophysical Journal [Internet]. 2006;91(12):4490–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33845414566&doi=10.1529%252fbiophysj.106.087767&partnerID=40&md5=61066b2a0e379c2abf1e7fefaa98288b

22.

Sterin M, Cohen JS, Ringel I. Hormone sensitivity is reflected in the phospholipid profiles of breast cancer cell lines. Breast Cancer Research and Treatment [Internet]. 2004;87(1):1–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-4544278657&doi=10.1023%252fB%253aBREA.0000041572.07837.ec&partnerID=40&md5=c31306223450371cfe482cd87a4339da

23.

Cohen JS, Motiei M, Carmi S, Shiperto D, Yefet O, Ringel I. Determination of Intracellular pH and Compartmentation Using Diffusion-Weighted NMR Spectroscopy with pH-Sensitive Indicators. Magnetic Resonance in Medicine [Internet]. 2004;51(5):900–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-2342522713&doi=10.1002%252fmrm.20034&partnerID=40&md5=4ee5bbf648f3711b97d28a30d699a5ed

24.

Sterin M, Ringel I, Ringel I, Berman E, Cohen JS, Mardor Y. Levels of phospholipid metabolites in breast cancer cells treated with antimitotic drugs: A 31P-magnetic resonance spectroscopy study. Cancer Research [Internet]. 2001;61(20):7536–43. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035887490&partnerID=40&md5=8b9e046751f1388341361fd4328346de

25.

Mardor Y, Kaplan O, Sterin M, Ruiz-Cabello J, Ash E, Roth Y, et al. Noninvasive real-time monitoring of intracellular cancer cell metabolism and response to lonidmnine treatment using diffusion weighted proton magnetic resonance spectroscopy. Cancer Research [Internet]. 2000;60(18):5179–86. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034665565&partnerID=40&md5=a73b81034514d7cf125d98c869eb6496

26.

Epstein E, Sela-Brown A, Ringel I, Kilav R, King SM, Benashski SE, et al. Dynein light chain binding to a 3’-untranslated sequence mediates parathyroid hormone mRNA association with microtubules. Journal of Clinical Investigation [Internet]. 2000;105(4):505–12. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034000792&doi=10.1172%252fJCI8557&partnerID=40&md5=a6122892d5a690d3248da032c4755f78

27.

Barasch D, Zipori O, Ringel I, Ginsburg I, Samuni A, Katzhendler J. Novel anthraquinone derivatives with redox-active functional groups capable of producing free radicals by metabolism: Are free radicals essential for cytotoxicity? European Journal of Medicinal Chemistry [Internet]. 1999;34(7–8):597–615. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032710427&doi=10.1016%2fS0223-5234%2800%2980029-X&partnerID=40&md5=40626a72d7364344f918ff49f10e630b

28.

Gorodetsky R, Levdansky L, Ringel I, Vexler A. Paclitaxel-induced modification of the effects of radiation and alterations in the cell cycle in normal and tumor mammalian cells. Radiation Research [Internet]. 1998;150(3):283–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031657209&doi=10.2307%252f3579977&partnerID=40&md5=1dce2096528059ceb0291775bddaf09f

29.

Moyna G, Williams HJ, Scott AI, Ringel I, Gorodetsky R, Swindell CS. Conformational studies of paclitaxel analogs modified at the C-2’ position in hydrophobic and hydrophilic solvent systems. Journal of Medicinal Chemistry [Internet]. 1997;40(20):3305–11. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030846178&doi=10.1021%252fjm970026%252b&partnerID=40&md5=767b51d69349960a873e5e2932ab96a2

30.

Nativ O, Aronson M, Medalia O, Moldavsky T, Sabo E, Ringel I, et al. Anti-neoplastic activity of paclitaxel on experimental superficial bladder cancer: In vivo and in vitro studies. International Journal of Cancer [Internet]. 1997;70(3):297–301. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031053304&doi=10.1002%2f%28SICI%291097-0215%2819970127%2970%3a3%3c297%3a%3aAID-IJC9%3e3.0.CO%3b2-S&partnerID=40&md5=97e49b761c7e976f136c6a47a955bc1d

31.

Gibson D, Binyamin I, Haj M, Ringel I, Ramu A, Katzhendler J. Anthraquinone intercalators as carrier molecules for second-generation platinum anticancer drugs. European Journal of Medicinal Chemistry [Internet]. 1997;32(10):823–31. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030736636&doi=10.1016%2fS0223-5234%2899%2980068-3&partnerID=40&md5=696872320996f3754d2619a723c4823b

32.

Katzhendler J, Ringel I, Karaman R, Zaher H, Breuer E. Acylphosphonate hemiketals - Formation rate and equilibrium. The electron-withdrawing effect of dimethoxyphosphinyl group. Journal of the Chemical Society Perkin Transactions 2 [Internet]. 1997;(2):341–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000734283&doi=10.1039%252fa604196e&partnerID=40&md5=f4f17b6c07ff5155ad3722602e38f85f

33.

Ringel I, Gottfried V, Levdansky L, Winkelman JW, Kimel S. Photodynamic activity of porphines on tubulin assembly. In: Proceedings of SPIE - The International Society for Optical Engineering [Internet]. 1996. p. 156–63. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029710227&partnerID=40&md5=98ced51b30f6316d26b10712710f35ef

34.

Doungdee P, Sarel S, Ringel I, Gibson D, Wongvisetsirikul N, Avramovici-Grisaru S. Iron chelators of the pyridoxal 2-pyridyl hydrazone class. part III.1 Ionisation and conformational characteristics of the ligands. Heterocycles [Internet]. 1995;40(1):241–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33745484074&doi=10.3987%252fcom-94-s16&partnerID=40&md5=fa6928b5a8eefe44f58c81f0b8a79941

35.

Muhlrad A, Ringel I. Use of vanadate-induced photocleavage for detecting phosphate binding sites in proteins. Metal ions in biological systems [Internet]. 1995;31:211–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029436612&partnerID=40&md5=458db47e3495441263ad34d4ed47dad9

36.

Elisha Z, Havin L, Ringel I, K.yisraeli J. Vg1 RNA binding protein mediates the association of Vg1 RNA with microtubules in Xenopus oocytes. EMBO Journal [Internet]. 1995;14(20):5109–14. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028822529&doi=10.1002%252fj.1460-2075.1995.tb00193.x&partnerID=40&md5=580598575d1cefd552dc57b4ddd6c401

37.

Rao S, Krauss NE, Heerding JM, Swindell CS, Ringel I, Orr GA, et al. 3’-(p-Azidobenzamido)taxol photolabels the N-terminal 31 amino acids of β-tubulin. Journal of Biological Chemistry [Internet]. 1994;269(5):3132–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028169689&partnerID=40&md5=534de475f7691e3ba43c593dba452dc0

38.

Swindell CS, Heerding JM, Krauss NE, Horwitz SB, Ringel I. Characterization of the taxol structure-activity profile for the locus of the A-ring side chain. Bioorganic and Medicinal Chemistry Letters [Internet]. 1994;4(12):1531–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028283518&doi=10.1016%2fS0960-894X%2801%2980527-8&partnerID=40&md5=81ef5b30f147b3792b9dad92a13c3467

39.

Swindell CS, Heerding JM, Krauss NE, Horwitz SB, Rao S, Ringel I. Characterization of Two Taxol Photoaffinity Analogues Bearing Azide and Benzophenone-Related Photoreactive Substituents in the A-Ring Side Chain. Journal of Medicinal Chemistry [Internet]. 1994;37(10):1446–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028200190&doi=10.1021%252fjm00036a009&partnerID=40&md5=34e45755accde4b1a64a89a57e87f155

40.

Domb AJ, Ringel I. Polymeric Drug Carrier Systems in the Brain. Methods in Neurosciences [Internet]. 1994;21(C):169–83. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011588639&doi=10.1016%252fB978-0-12-185291-7.50016-3&partnerID=40&md5=db1708379be19c8fb10eb3629846b627

41.

Rasouly D, Rahamim E, Ringel I, Ginzburg I, Muarakata C, Matsuda Y, et al. Neurites induced by staurosporine in PC12 cells are resistant to colchicine and express high levels of tau proteins. Molecular Pharmacology [Internet]. 1994;45(1):29–35. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028081945&partnerID=40&md5=195b33001d926196435f6d51e6ff56cb

42.

Horwitz SB, Cohen D, Rao S, Ringel I, Shen HJ, Yang CP. Taxol: mechanisms of action and resistance. Journal of the National Cancer Institute Monographs [Internet]. 1993;(15):55–61. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027829631&partnerID=40&md5=e7617fcf517f84494b6d41da2e0384e2

43.

Carboni JM, Farina V, Rao S, Hauck SI, Horwitz SB, Ringel I. Synthesis of a Photoaffinity Analog of Taxol as an Approach To Identify the Taxol Binding Site on Microtubules. Journal of Medicinal Chemistry [Internet]. 1993;36(4):513–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0027475555&doi=10.1021%252fjm00056a013&partnerID=40&md5=6e7bd8ad63f13b62afd7f236b8141b46

44.

Rao S, Horwitz SB, Ringel I. Direct photoaffinity labeling of tubulin with taxol. Journal of the National Cancer Institute [Internet]. 1992;84(10):785–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026747827&doi=10.1093%252fjnci%252f84.10.785&partnerID=40&md5=efe6ca38038fb321638b4fe2ad519061

45.

Ringel I, Horwitz SB. Effect of alkaline pH on taxol-microtubule interactions. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1991;259(2):855–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026347760&partnerID=40&md5=75dacf6ba29ecbaa2b6fdcae9863d483

46.

Ringel I, Jaffe D, Alerhand S, Boye O, Muzaffar A, Brossi A. Fluorinated Colchicinoids: Antitubulin and Cytotoxic Properties. Journal of Medicinal Chemistry [Internet]. 1991;34(11):3334–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026351383&doi=10.1021%252fjm00115a026&partnerID=40&md5=a7f4d8d86651b1de3272d7a1e0da11e0

47.

Osei AA, Everett GW, Ringel I, Himes RH. The interaction of [13C]-enriched colchicine with tubulin as determined by NMR spectroscopy. Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular [Internet]. 1991;1078(3):339–44. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026423011&doi=10.1016%2f0167-4838%2891%2990154-R&partnerID=40&md5=09d196411b58df632c29a2d7d42eb4a5

48.

Swindell CS, Krauss NE, Horwitz SB, Ringel I. Biologically Active Taxol Analogues with Deleted A-Ring Side Chain Substituents and Variable C-2′ Configurations. Journal of Medicinal Chemistry [Internet]. 1991;34(3):1176–84. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025827992&doi=10.1021%252fjm00107a042&partnerID=40&md5=dfb3eab9ff2e1766ecdc00b6adf77fea

49.

Ringel I, Horwitz SB. Studies with RP 56976 (taxotere): A semisynthetic analogue of taxol. Journal of the National Cancer Institute [Internet]. 1991;83(4):288–91. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026428123&doi=10.1093%252fjnci%252f83.4.288&partnerID=40&md5=c598abe32717d9e8bd782efdfb907769

50.

Gibson D, Gean KF, Ben-Shoshan R, Katzhendler J, Ramu A, Ringel I. Preparation, Characterization, and Anticancer Activity of a Series of cis-PtCl2 Complexes Linked to Anthraquinone Intercalators. Journal of Medicinal Chemistry [Internet]. 1991;34(1):414–20. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026087006&doi=10.1021%252fjm00105a063&partnerID=40&md5=eeff68de4db9bcff08c80b4337971ee9

51.

Muhlrad A, Michael Peyser Y, Ringel I. Effect of Actin, ATP, Phosphates, and pH on Vanadate-Induced Photocleavage of Myosin Subfragment 1. Biochemistry [Internet]. 1991;30(4):958–65. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026062348&doi=10.1021%252fbi00218a011&partnerID=40&md5=8d8df843986c2ac059749d161874ddda

52.

Gean K, Ben-Shoshan R, Ramu A, Ringel I, Katzhendler J, Gibson D. Preparation, characterization and the anticancer activity of a novel series of triaminemonochloroplatinum(II) cations linked to anthraquinone intercalators. European Journal of Medicinal Chemistry [Internet]. 1991;26(6):593–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026003002&doi=10.1016%2f0223-5234%2891%2990193-Q&partnerID=40&md5=be3168f16ef05177d9e5a4567320ab0c

53.

MUHLRAD A, PEYSER YM, RINGEL I. Effects of ions on vanadate‐induced photocleavage of myosin subfragment 1. European Journal of Biochemistry [Internet]. 1991;201(2):409–15. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025939552&doi=10.1111%252fj.1432-1033.1991.tb16298.x&partnerID=40&md5=a807937118ea600391d0d39ee3f0f1d3

54.

Ringel I, Peyser YM, Muhlrad A. 51V NMR Study of Vanadate Binding to Myosin and Its Subfragment 1. Biochemistry [Internet]. 1990;29(38):9091–6. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025196786&doi=10.1021%252fbi00490a029&partnerID=40&md5=93d795138e2b5b84226fe93729413cbc

55.

Katzhendler J, Ringel I, Goldblum A, Gibson D, Tashma Z. Conformational studies of substituted five-membered cyclic carbonates and related compounds by MNDO, and the X-ray crystal structure of 4-chlorophenyloxymethyl-1,3-dioxolan-2-one. Journal of the Chemical Society, Perkin Transactions 2 [Internet]. 1989;(11):1729–39. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049078411&partnerID=40&md5=2437002a0b4d9628d705147d4611be7b

56.

Katzhendler J, Gean KF, Bar-Ad G, Tashma Z, Ben-Shoshan R, Ringel I, et al. Synthesis of aminoanthraquinone derivatives and their in vitro evaluation as potential anti-cancer drugs. European Journal of Medicinal Chemistry [Internet]. 1989;24(1):23–30. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024578824&doi=10.1016%2f0223-5234%2889%2990159-1&partnerID=40&md5=cf74134bcefede8f7652b3a5cb99e153

57.

Katzhendler J, Cohen S, Rahamim E, Weisz M, Ringel I, Deutsch J. The effect of spacer, linkage and solid support on the synthesis of oligonucleotides. Tetrahedron [Internet]. 1989;45(9):2777–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024573830&doi=10.1016%2fS0040-4020%2801%2980108-3&partnerID=40&md5=93e4169292748d416c785f2fe3beacd7

58.

Katzhendler J, Bar-Ad G, Haran M, Gean KF, Tashma Z, Ringel I, et al. The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells. Drug Design and Delivery [Internet]. 1989;4(4):289–94. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024363288&partnerID=40&md5=efa7cfa3336c5c3134d639a2bd4a72b0

59.

Ringel I, Bakshi O, Mellado W, Ramu A, Gibson D, Katzhendler J. N-Alkyl colchiceineamides: their inhibition of GTP or taxol-induced assembly of tubulin. Biochemical Pharmacology [Internet]. 1988;37(12):2487–9. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023922647&doi=10.1016%2f0006-2952%2888%2990380-2&partnerID=40&md5=38e961657809b5cecc01c5e91064c71b

60.

Katzhendler J, Goldblum A, Ringel I. Kinetic and theoretical considerations in the hydrolysis of iminocarbonates. Journal of the Chemical Society, Perkin Transactions 2 [Internet]. 1988;(9):1653–60. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049068424&doi=10.1039%252fP29880001653&partnerID=40&md5=7a29f85aa15905df0947cf74ee5a6768

61.

Kitov S, Ben-Shoshan R, Ringel I, Gibson D, Katzhendler J. The effect of cis-platin analogues derived from aminoalkylaminoanthraquinones on DNA cleavage: an electron microscopy study. European Journal of Medicinal Chemistry [Internet]. 1988;23(4):381–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023772990&doi=10.1016%2f0223-5234%2888%2990213-9&partnerID=40&md5=f8a5aab82509339722dbf2b109e4c4d4

62.

Rav-Acha Ch, Ringel I, Sarel S, Katzhendler J. The catalytic effect of catiohic amino micelles on the hydrolysis of substituted phenyl esters. Tetrahedron [Internet]. 1988;44(18):5879–92. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0003658150&doi=10.1016%2fS0040-4020%2801%2981445-9&partnerID=40&md5=d1c3b25856447da2a4b9063c75ea8810

63.

Tashma Z, Deutsch J, Cohen S, Weisz M, Katzhendler J, Ringel I. An improved method for the preparation of methyl dichlorophosphite. A key reagent in the phosphite method of oligonucleotide synthesis. Nucleosides and Nucleotides [Internet]. 1987;6(3):589–95. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953486346&doi=10.1080%252f07328318708069988&partnerID=40&md5=f440d3ac9f4b22e8b2ad0541906fa897

64.

Ringel I, Horwitz SB. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. Journal of Pharmacology and Experimental Therapeutics [Internet]. 1987;242(2):692–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023199652&partnerID=40&md5=372132e28cd64f8810b906fa1d01cd6f

65.

Katzhendler J, Cohen S, Weisz M, Ringel I, Camerini-Oterio RD, Deutsch J. Spacer effect on the synthesis of oligodeoxynucleotides by the phosphite method. Reactive Polymers, Ion Exchangers, Sorbents [Internet]. 1987;6(2–3):175–87. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022797655&doi=10.1016%2f0167-6989%2887%2990087-0&partnerID=40&md5=3a93b12a323afe72daf1aee5fc84899f

66.

Ringel I, Sternlicht H. Carbon-13 Nuclear Magnetic Resonance Study of Microtubule Protein: Evidence for a Second Colchicine Site Involved in the Inhibition of Microtubule Assembly. Biochemistry [Internet]. 1984;23(23):5644–53. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021710174&doi=10.1021%252fbi00318a040&partnerID=40&md5=5d7386b42d60a2c2cb390c2f8a7bb782

67.

Sternlicht H, Ringel I, Szasz J. Theory for modeling the copolymerization of tubulin and tubulin-colchicine complex. Biophysical Journal [Internet]. 1983;42(3):255–67. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020572319&doi=10.1016%2fS0006-3495%2883%2984393-8&partnerID=40&md5=1b4cd8499deccf02e517b70ec33e2fce

68.

Sternlicht H, Ringel I, Szasz J. The co-polymerization of tubulin and tubulin chochicine complex in the absence and presence of associated proteins. Journal of Biological Chemistry [Internet]. 1980;255(19):9138–48. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019321642&partnerID=40&md5=6af9d50fc4ff4dc914b44d0f0f48c70d

69.

Sternlicht H, Ringel I, Szasz J. A kinetic model for colchicine inhibition of microtubule assembly. Biophysical Journal [Internet]. 1980;32(1):445–8. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019137727&doi=10.1016%2fS0006-3495%2880%2984976-9&partnerID=40&md5=05ea331d4f5a3a802826db51588b77c8

70.

Sarel S, Langbeheim M, Ringel I. Trieneiron tricarbonyl and bisallyldi-iron hexacarbonyl π-complexes from photolysis of divinylcyclopropanes induced by iron pentacarbonyl. Journal of the Chemical Society, Chemical Communications [Internet]. 1979;(2):73–5. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049106465&doi=10.1039%252fC39790000073&partnerID=40&md5=52b9f4302171e23501325c1cdd1686d8

71.

Sternlicht H, Ringel I. Colchicine inhibition of microtubule assembly via copolymer formation. Journal of Biological Chemistry [Internet]. 1979;254(20):10540–50. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018622376&partnerID=40&md5=32a9192e750aa811ba01e5cd54113567

72.

Sternlicht H, Ringel I, Szasz J. Colchicine inhibition of microtubule assembly via copolymer formation. Journal of Cell Biology [Internet]. 1979;83(2 II):No. MT1845. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0018568514&partnerID=40&md5=fb1b5a0f79d03df5b30fe894816c44fc

73.

Victor R, Ringel I. 1H and 13C n.m.r. study of butatriene‐bis‐tricarbonyliron complexes. Assignment of geometric orientation by comparative J(CCCH) values. Organic Magnetic Resonance [Internet]. 1978;11(1):31–3. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84913796977&doi=10.1002%252fmrc.1270110108&partnerID=40&md5=b868f672d42b6e23a93ad064489e3c4a

74.

Sternlicht H, Ringel I. Colchicine inhibition of microtubule assembly. Federation Proceedings [Internet]. 1978;37(6):No. 2861. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0017852018&partnerID=40&md5=41d4fdb56873ca667004132229bf9477

75.

Breuer E, Somekh L, Ringel I. N.m.r. spectra of cyclic amines. II—Factors influencing the chemical shifts of α‐protons in aziridines. Organic Magnetic Resonance [Internet]. 1977;9(6):328–32. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84986840349&doi=10.1002%252fmrc.1270090609&partnerID=40&md5=05cc70b27fe706cd070dd0872d8f44ee

76.

Katzhendler J, Ringel I, Sarel S. Organic carbonates. Part XIV. Polar and steric effects of substituents influencing the modes of ring-opening of highly-branched ethylene and trimethylene carbonates by various nucleophiles: A nuclear magnetic resonance study. Journal of the Chemical Society, Perkin Transactions 2 [Internet]. 1972;(14):2019–25. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-37049123150&doi=10.1039%252fp29720002019&partnerID=40&md5=a68c34f34d109d706da49be39a1678d7

77.

Lichtenberg D, Bergmann F, Ringel I. Assignment of individual signals of aromatic protons in the NMR spectrum of 6-substituted purines. Journal of Magnetic Resonance (1969) [Internet]. 1972;6(4):600–4. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0348067600&doi=10.1016%2f0022-2364%2872%2990170-9&partnerID=40&md5=02e98454c0bdef104ba4523044435bfa